"Eastern Europe," in a geomedical context, often refers to a region including countries that were once part of the Soviet Union or influenced by its culture and healthcare system, such as Russia, Ukraine, Belarus, and sometimes including countries in the Balkan Peninsula and Baltic states."
Created 1 January 1993 as a result of the division of Czechoslovakia into the Czech Republic and Slovakia.
A filarial parasite primarily affecting dogs and cats, but causing an emerging zoonosis in humans involving subcutaneous lesions. It is transmitted by MOSQUITOES.
Ethnic group originating in India and entering Europe in the 14th or 15th century.
Created as a republic in 1918 by Czechs and Slovaks from territories formerly part of the Austro-Hungarian Empire. The country split into the Czech Republic and Slovakia 1 January 1993.
A plant family of the order Violales, subclass Dilleniidae, class Magnoliopsida. The common name of rock rose is used with several plants of this family.
A subclass of segmented worms comprising the tapeworms.
Created 1 January 1993 as a result of the division of Czechoslovakia into the Czech Republic and Slovakia.
The science of developing, caring for, or cultivating forests.
I'm sorry for any confusion, but "Romania" is a country located in southeastern Europe, not a medical term. It is not possible to provide a medical definition for it.
A species of gram-negative bacteria in the genus ANAPLASMA, family ANAPLASMATACEAE, formerly called Ehrlichia phagocytophila or Ehrlichia equi. This organism is tick-borne (IXODES) and causes disease in horses and sheep. In humans, it causes human granulocytic EHRLICHIOSIS.
An incision of the posterior vaginal wall and a portion of the pudenda which enlarges the vaginal introitus to facilitate delivery and prevent lacerations.
I'm sorry for any confusion, but "Hungary" is not a medical term; it is a country located in Central Europe, and its name should not be used in the context of medical definitions.
I'm sorry for any confusion, but 'Europe' is a geographical continent and not a medical term; therefore, it doesn't have a medical definition.
Onset of HYPERREFLEXIA; SEIZURES; or COMA in a previously diagnosed pre-eclamptic patient (PRE-ECLAMPSIA).
A genus of the family BUNYAVIRIDAE causing HANTAVIRUS INFECTIONS, first identified during the Korean war. Infection is found primarily in rodents and humans. Transmission does not appear to involve arthropods. HANTAAN VIRUS is the type species.
Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.
Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.
The largest genus of TICKS in the family IXODIDAE, containing over 200 species. Many infest humans and other mammals and several are vectors of diseases such as LYME DISEASE, tick-borne encephalitis (ENCEPHALITIS, TICK-BORNE), and KYASANUR FOREST DISEASE.
A species of gram-negative bacteria that grows preferentially in the vacuoles of the host cell. It is the etiological agent of Q FEVER.
An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of FEVER; HEADACHE; malaise; and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals (ANIMALS, DOMESTIC).
Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.
An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.
EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.
The science dealing with the earth and its life, especially the description of land, sea, and air and the distribution of plant and animal life, including humanity and human industries with reference to the mutual relations of these elements. (From Webster, 3d ed)
The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
An infant during the first month after birth.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Q fever in Bulgaria and Slovakia. (1/167)

As a result of dramatic political and economic changes in the beginning of the 1990s, Q-fever epidemiology in Bulgaria has changed. The number of goats almost tripled; contact between goat owners (and their families) and goats, as well as goats and other animals, increased; consumption of raw goat milk and its products increased; and goats replaced cattle and sheep as the main source of human Coxiella burnetii infections. Hundreds of overt, serologically confirmed human cases of acute Q fever have occurred. Chronic forms of Q fever manifesting as endocarditis were also observed. In contrast, in Slovakia, Q fever does not pose a serious public health problem, and the chronic form of infection has not been found either in follow-ups of a Q-fever epidemic connected with goats imported from Bulgaria and other previous Q-fever outbreaks or in a serologic survey. Serologic diagnosis as well as control and prevention of Q fever are discussed.  (+info)

Short report: simultaneous occurrence of Dobrava, Puumala, and Tula Hantaviruses in Slovakia. (2/167)

The prevalence of antibody to hantaviruses in Slovakia (serum panel n = 2,133) was lower in the western part (0.54%) and higher in the eastern part (1.91%) of the country and was found to be significantly enhanced in a group of forest workers from eastern Slovakia (5.88%). One-third of the IgM-negative convalescent phase sera from patients with hemorrhagic fever with renal syndrome exhibited antibodies reacting predominantly with Puumala virus antigen, while two-thirds had antibodies directed mainly against Hantaan virus antigen. Fine analysis of two Hantaan virus-reactive sera by a focus reduction neutralization test showed that Dobrava hantavirus was the source of these human infections. Initial results of rodent screening indicated the circulation of Dobrava virus in populations of striped field mice (Apodemus agrarius) in eastern Slovakia.  (+info)

Analysis of the SMN and NAIP genes in slovak spinal muscular atrophy patients. (3/167)

We identified homozygous absence of exon 7 of the telomeric copy of the survival motor neuron gene (telSMN) in 88.4% (38/43) of spinal muscular atrophy (SMA) patients from Slovakia. Additional deletions within the neuronal apoptosis inhibitory protein (NAIP) gene were found in 38.5% of type I, 12.5% of type II and never in type III SMA patients. Neither the SMN nor the NAIP gene was deleted in 81 healthy relatives and 25 controls tested. In one family, pseudodominant inheritance was identified. Both the type III SMA father and type II SMA son carried the homozygous deletion of the telSMN gene. One SMA I patient showed an SMN hybrid gene, probably created by intrachromosomal deletion. In two haploidentical type II SMA sibs, the telSMN exon 7 was absent on one chromosome, while the other carried an A-->G transition 96 bp upstream of exon 7 of the telSMN gene, a potential disease-causing mutation in these patients.  (+info)

High frequency of alkaptonuria in Slovakia: evidence for the appearance of multiple mutations in HGO involving different mutational hot spots. (4/167)

Alkaptonuria (AKU) is an autosomal recessive disorder caused by the deficiency of homogentisate 1,2 dioxygenase (HGO) activity. AKU shows a very low prevalence (1:100,000-250,000) in most ethnic groups. One notable exception is in Slovakia, where the incidence of AKU rises to 1:19,000. This high incidence is difficult to explain by a classical founder effect, because as many as 10 different AKU mutations have been identified in this relatively small country. We have determined the allelic associations of 11 HGO intragenic polymorphisms for 44 AKU chromosomes from 20 Slovak pedigrees. These data were compared to the HGO haplotype data available in our laboratory for >80 AKU chromosomes from different European and non-European countries. The results show that common European AKU chromosomes have had only a marginal contribution to the Slovak AKU gene pool. Six of the ten Slovak AKU mutations, including the prevalent G152fs, G161R, G270R, and P370fs mutations, most likely originated in Slovakia. Data available for 17 Slovak AKU pedigrees indicate that most of the AKU chromosomes have their origins in a single very small region in the Carpathian mountains, in the northwestern part of the country. Since all six Slovak AKU mutations are associated with HGO mutational hot spots, we suggest that an increased mutation rate at the HGO gene is responsible for the clustering of AKU mutations in such a small geographical region.  (+info)

Effect of diet and 677 C-->T 5, 10-methylenetetrahydrofolate reductase genotypes on plasma homocyst(e)ine concentrations in slovak adolescent population. (5/167)

The objective of this study was to evaluate the effect of diet and 677 C-->T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene on plasma homocyst(e)ine concentrations in an adolescent population (113 males, age: 14.2+/-2.4 years; 202 females, age: 14.9+/-2.1 years) from a region characterized by high cardiovascular mortality. Homocyst(e)ine levels did not differ between males and females (9.4+/-3.5 and 8.9+/-3.1 micromol/l, respectively). The homozygosity for the 677 C-->T MTHFR mutation was found in 4.6 % of subjects. No differences in homocyst(e)ine levels were found between MTHFR genotypes. Analysis of the diet composition which was performed on a 24-hour daily recall basis and a food frequency questionnaire showed a low daily intake of vitamin B6 (males: 1.13 mg/66% RDA; females: 0.92 mg/61% RDA). Daily folic acid intake was 0.21 g/105% RDA in males and 0.23 g/115% RDA in females. The results of our study show that the high homocyst(e)ine levels in the adolescent population were not affected by the 677 C-->T MTHFR mutation. We conclude that an insufficient dietary intake of vitamin B6 and folic acid is responsible for this finding. This is in accord with the recommendation that the dietary allowances for folate should be reset to the originally prescribed levels of 0.4 g/day which should be sufficient to control the homocysteine levels.  (+info)

A new geographical gradient in vole population dynamics. (6/167)

A new geographical gradient in the dynamics of small rodents is demonstrated by analysing 29 time series of density indices of the common vole (Microtus arvalis) from Poland, the Czech Republic and the Slovak Republic. This gradient extends from more stable northerly populations in coastal Poland to more variable and cyclic populations in the southernmost parts of the Slovak Republic, and is hence a reversal of the Fennoscandian gradient. All studied variables (such as mean density, cycle amplitude, density variability and the coefficients in a second-order autoregressive model) exhibit consistent latitudinal variation. Possible underlying factors are discussed. In particular, we suggest that seasonality may be a key element in explaining the observed new gradient.  (+info)

Lactate dehydrogenase activity in human placenta following exposure to environmental pollutants. (7/167)

The impact of environmental pollution at the place of residence of pregnant women and of their smoking habits on the cellular energy metabolism of placental tissue was investigated. Samples of full-term placentas were randomly collected from two environmentally different regions of Slovakia (Bratislava, Stara Lubovna) and the activity of lactate dehydrogenase (LDH) was measured. Our results showed enhanced LDH activity in the placenta that was dependent on both the type of environmental pollutants at the place of residence and the smoking habits during pregnancy. The enhanced LDH activity may reflect hypoxic conditions due to the accumulation of heavy metals and toxic compounds of tobacco smoke in the placental tissue. A high content of heavy metal particles, found in placental samples from Stara Lubovna in our previous studies, might contribute to the increased LDH activity in placentas from this region. We hypothesize that fine metal particles deposited in the placental tissue might be phagocytozed by the syncytiotrophoblast, thus contributing to the decreased oxygen level in placental tissue.  (+info)

Epidemiological survey of human borreliosis diagnosed in Eastern Slovakia. (8/167)

439 sera of patients from eastern Slovakia suspected of Lyme borreliosis were examined for anti-Borrelia IgG and IgM antibodies by ELISA (Ezygnost, Dade Behring, Germany). Out of the total number of 64 sera, e.g. in 14.6% found anti-Borrelia antibodies were. Among seropositive patients, 54.7% were women and 45.3% men. The highest incidence of the disease was diagnosed in the group of women aged 55-64 and men aged 45-54. Out of 29 positive sera of men, 55.2% had IgG antibodies, 27.6% IgM antibodies and 17.2% both types of antibodies. Out of 35 positive sera of women, 48.6% had IgG antibodies, 40.0% IgM antibodies and 11.4% both types of antibodies. Erythema Chronicum Migrans--ECM (31.3%) and arthritis (25.0%) prevailed among clinical symptoms, in contrast with only 7.8% of neurological cases. In men, arthritis most frequently occurred (27.6%), while in women erythema migrans forms (37.1%). Other manifestations of the disease appeared in 13 patients (20.3%), and 10 patients (15.6%) had no record of clinical manifestations. As shown by patients' records, 32.8% reported attachment of tick, 20.3% insect bites and 29.7% were not aware of being bitten by vectors. Seasonal dynamics of diagnosed cases reached three peaks with the highest numbers in February, May and October.  (+info)

Eastern Europe is a geographical and political region of the European continent. The exact definition of Eastern Europe varies, but it generally includes the countries in Central and Eastern Europe that were part of the Soviet Union or aligned with the Soviet Union during the Cold War. These countries include:

* Belarus
* Bulgaria
* Czech Republic
* Hungary
* Moldova
* Poland
* Romania
* Russia (European portion)
* Slovakia
* Ukraine

Some definitions of Eastern Europe also include the Baltic states (Estonia, Latvia, and Lithuania), which were part of the Soviet Union but are now independent countries. Other definitions may also include Albania, Bosnia and Herzegovina, Croatia, Montenegro, North Macedonia, Serbia, and Slovenia, which were part of the Eastern Bloc but not part of the Soviet Union.

It is important to note that the term "Eastern Europe" can be seen as problematic and outdated, as it is often associated with negative stereotypes and historical connotations from the Cold War era. Many people prefer to use more specific terms, such as "Central Europe," "Eastern Bloc," or "Soviet Union," to describe the region.

The Czech Republic is a country located in Central Europe. It is not a medical term or concept, so it does not have a specific medical definition. However, like any other country, the Czech Republic has its own healthcare system and medical facilities that provide various health services to its population. The Czech Republic is known for its high-quality healthcare and medical education, with many institutions being recognized worldwide.

Dirofilaria repens is a species of parasitic roundworm that can infect various mammals, including humans. It is primarily transmitted through the bite of infected mosquitoes. The adult worms typically reside in the subcutaneous tissues or within body cavities of the definitive host (usually dogs and other canids), where they can cause a condition known as dirofilariasis.

In humans, D. repens infections are often asymptomatic or may present with non-specific symptoms such as localized swelling, itching, or pain at the site of infection. Occasionally, more severe complications like blindness can occur if the worms invade the eye. Treatment typically involves surgical removal of the worms and sometimes medication to eliminate any remaining larvae. Preventive measures include avoiding mosquito bites and administering preventative treatments to pets in endemic areas.

I believe there may be some confusion in your question. "Gypsies" is a term often used to refer to the Romani people, who are an ethnic group with a unique language and culture. It's important to note that using the term "Gypsy" as a medical label or definition can be considered pejorative and disrespectful, as it has been historically associated with discrimination and negative stereotypes.

If you're asking for a medical definition related to Romani people, there isn't one, as they are an ethnic group and not a medical condition. However, if you have any specific medical concerns or conditions in mind, I would be happy to help provide a definition or explanation for those.

Czechoslovakia was a sovereign state in Central Europe that existed from October 28, 1918, when it declared its independence from the Austro-Hungarian Empire, until January 1, 1993. On that date, Czechoslovakia underwent a "velvet divorce" into two separate countries, the Czech Republic and Slovakia.

The medical definition of 'Czechoslovakia' is not applicable as it was a country and not a medical term or condition.

Cistaceae is a family of flowering plants, also known as the rock-rose family. It includes around 20 genera and 200 species of herbaceous plants, shrubs, and small trees that are native to Europe, Africa, and Asia. These plants are characterized by their showy, often pink or purple, flowers and their sticky, resinous leaves. Some well-known members of this family include the common rock-rose (Cistus salvifolius) and the blue-eyed grass (Sisyrinchium bellum).

Cestoda is a class of parasitic worms belonging to the phylum Platyhelminthes, also known as flatworms. Cestodes are commonly known as tapeworms and have a long, flat, segmented body that can grow to considerable length in their adult form. They lack a digestive system and absorb nutrients through their body surface.

Cestodes have a complex life cycle involving one or two intermediate hosts, usually insects or crustaceans, and a definitive host, which is typically a mammal, including humans. The tapeworm's larval stage develops in the intermediate host, and when the definitive host consumes the infected intermediate host, the larvae mature into adults in the host's intestine.

Humans can become infected with tapeworms by eating raw or undercooked meat from infected animals or through accidental ingestion of contaminated water or food containing tapeworm eggs or larvae. Infection with tapeworms can cause various symptoms, including abdominal pain, diarrhea, weight loss, and vitamin deficiencies.

I'm sorry for any confusion, but "Slovakia" is not a medical term. It is a country located in Central Europe. If you have any questions about medical terms or concepts, I would be happy to help answer those for you.

I'm sorry for any confusion, but "Forestry" is not a medical term. Forestry is the science and practice of managing forests, plantations, and associated resources for timber, wildlife, recreation, conservation, and other benefits. It involves the application of ecological principles, silvicultural techniques, and management strategies to ensure the sustainability and health of forest ecosystems.

I'm sorry for any confusion, but "Romania" is not a medical term. It is a country located in southeastern Europe. If you have any questions about medical terminology or health-related topics, I would be happy to help. Could you please clarify your question?

'Anaplasma phagocytophilum' is a gram-negative bacterium that causes Anaplasmosis, a tick-borne disease in humans. It infects and survives within granulocytes, a type of white blood cell, leading to symptoms such as fever, headache, muscle pain, and chills. In severe cases, it can cause complications like respiratory failure, disseminated intravascular coagulation, and even death. It is transmitted through the bite of infected ticks, primarily the black-legged tick (Ixodes scapularis) in the United States and the sheep tick (Ixodes ricinus) in Europe. Proper diagnosis and treatment with antibiotics are crucial for managing this infection.

An episiotomy is a surgical incision made in the perineum, the area between the vagina and the anus, during childbirth to widen the opening of the vagina and facilitate the delivery of the baby. It is typically performed when there is a risk of severe tearing or if the baby is showing signs of distress and needs to be delivered quickly. The incision is usually made with scissors or a scalpel, and it can be either midline (cut along the midline of the perineum) or mediolateral (cut diagonally from the vaginal opening toward the side of the buttocks). After delivery, the incision is stitched up.

Episiotomy was once a routine procedure during childbirth, but its use has become less common in recent years due to increasing evidence that it may not provide any significant benefits and can actually increase the risk of complications such as pain, infection, and difficulty with urination or bowel movements. Current guidelines recommend that episiotomies should only be performed when medically necessary and after informed consent from the mother.

I'm sorry for any confusion, but "Hungary" is not a medical term or concept. It is a country located in Central Europe, known for its rich history, culture, and natural beauty. If you have any questions about medical topics or definitions, I would be happy to help!

I'm sorry for any confusion, but the term "Europe" is a geographical and political designation, rather than a medical one. It refers to the continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere. It is bordered by the Arctic Ocean to the north, the Atlantic Ocean to the west, and the Mediterranean Sea to the south. Europe is made up of approximately 50 countries, depending on how one defines a "country."

If you have any questions related to medical terminology or health-related topics, I'd be happy to help answer them!

Eclampsia is a serious pregnancy complication characterized by the onset of seizures or convulsions in a woman who has already developed preeclampsia, which is a condition marked by high blood pressure and damage to organs such as the liver and kidneys. Eclampsia can occur before, during, or after delivery and is considered a medical emergency that requires immediate treatment. It can pose significant risks to both the mother and the baby, including premature birth, fetal growth restriction, and even maternal and fetal death.

The exact causes of eclampsia are not fully understood, but it is thought to be related to problems with the placenta and abnormal blood vessel development in the uterus. Risk factors for developing eclampsia include preexisting medical conditions such as chronic hypertension or diabetes, a history of preeclampsia or eclampsia in previous pregnancies, multiple gestation (carrying more than one baby), and certain genetic factors.

Treatment for eclampsia typically involves delivering the baby as soon as possible to prevent further complications. In some cases, medication may be given to manage seizures and prevent their recurrence. Close monitoring of both the mother and the baby is essential to ensure the best possible outcomes.

Hantavirus is an etiologic agent for several clinical syndromes, including hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). It's a single-stranded RNA virus belonging to the family Bunyaviridae, genus Orthohantavirus.

These viruses are primarily transmitted to humans by inhalation of aerosolized excreta from infected rodents. The symptoms can range from flu-like illness to severe respiratory distress and renal failure, depending upon the specific hantavirus species. There are no known treatments for HFRS, but early recognition and supportive care can significantly improve outcomes. Ribavirin has been used in some cases of HPS with apparent benefit, although its general efficacy is not well-established

(References: CDC, NIH, WHO)

Polychlorinated biphenyls (PCBs) are a group of man-made organic chemicals consisting of 209 individual compounds, known as congeners. The congeners are formed by the combination of two benzene rings with varying numbers and positions of chlorine atoms.

PCBs were widely used in electrical equipment, such as transformers and capacitors, due to their non-flammability, chemical stability, and insulating properties. They were also used in other applications, including coolants and lubricants, plasticizers, pigments, and copy oils. Although PCBs were banned in many countries in the 1970s and 1980s due to their toxicity and environmental persistence, they still pose significant health and environmental concerns because of their continued presence in the environment and in products manufactured before the ban.

PCBs are known to have various adverse health effects on humans and animals, including cancer, immune system suppression, reproductive and developmental toxicity, and endocrine disruption. They can also cause neurological damage and learning and memory impairment in both human and animal populations. PCBs are highly persistent in the environment and can accumulate in the food chain, leading to higher concentrations in animals at the top of the food chain, including humans.

A disease reservoir refers to a population or group of living organisms, including humans, animals, and even plants, that can naturally carry and transmit a particular pathogen (disease-causing agent) without necessarily showing symptoms of the disease themselves. These hosts serve as a source of infection for other susceptible individuals, allowing the pathogen to persist and circulate within a community or environment.

Disease reservoirs can be further classified into:

1. **Primary (or Main) Reservoir**: This refers to the species that primarily harbors and transmits the pathogen, contributing significantly to its natural ecology and maintaining its transmission cycle. For example, mosquitoes are the primary reservoirs for many arboviruses like dengue, Zika, and chikungunya viruses.

2. **Amplifying Hosts**: These hosts can become infected with the pathogen and experience a high rate of replication, leading to an increased concentration of the pathogen in their bodies. This allows for efficient transmission to other susceptible hosts or vectors. For instance, birds are amplifying hosts for West Nile virus, as they can become viremic (have high levels of virus in their blood) and infect feeding mosquitoes that then transmit the virus to other animals and humans.

3. **Dead-end Hosts**: These hosts may become infected with the pathogen but do not contribute significantly to its transmission cycle, as they either do not develop sufficient quantities of the pathogen to transmit it or do not come into contact with potential vectors or susceptible hosts. For example, humans are dead-end hosts for many zoonotic diseases like rabies, as they cannot transmit the virus to other humans.

Understanding disease reservoirs is crucial in developing effective strategies for controlling and preventing infectious diseases, as it helps identify key species and environments that contribute to their persistence and transmission.

"Ixodes" is a genus of tick that includes several species known to transmit various diseases to humans and animals. These ticks are often referred to as "hard ticks" because of their hard, shield-like plate on their backs. Ixodes ticks have a complex life cycle involving three stages: larva, nymph, and adult. They feed on the blood of hosts during each stage, and can transmit diseases such as Lyme disease, Anaplasmosis, Babesiosis, and Powassan virus disease.

The most common Ixodes species in North America is Ixodes scapularis, also known as the black-legged tick or deer tick, which is the primary vector of Lyme disease in this region. In Europe, Ixodes ricinus, or the castor bean tick, is a widespread and important vector of diseases such as Lyme borreliosis, tick-borne encephalitis, and several other tick-borne pathogens.

Ixodes ticks are typically found in wooded or grassy areas with high humidity and moderate temperatures. They can be carried by various hosts, including mammals, birds, and reptiles, and can survive for long periods without feeding, making them efficient disease vectors.

Coxiella burnetii is a gram-negative, intracellular bacterium that causes Q fever, a zoonotic disease with various clinical manifestations ranging from asymptomatic seroconversion to acute and chronic forms. The bacterium is highly infectious and can be transmitted to humans through inhalation of contaminated aerosols or direct contact with infected animals or their products. C. burnetii has a unique ability to survive and replicate within host cells, particularly within phagocytic vacuoles, by inhibiting phagosome-lysosome fusion and altering the intracellular environment to promote its survival.

The bacterium exhibits a biphasic developmental cycle, consisting of small cell variants (SCVs) and large cell variants (LCVs). SCVs are metabolically inactive and highly resistant to environmental stressors, including heat, desiccation, and disinfectants. LCVs, on the other hand, are metabolically active and undergo replication within host cells. C. burnetii can form persistent infections, which may contribute to chronic Q fever and its associated complications, such as endocarditis and vascular infection.

Q fever is a worldwide distributed disease, with a higher incidence in rural areas where livestock farming is prevalent. The primary reservoirs for C. burnetii are domestic animals, including cattle, sheep, and goats, although wild animals and arthropods can also serve as potential hosts. Effective antibiotic treatment options for Q fever include doxycycline and fluoroquinolones, while vaccination with the phase I whole-cell vaccine is available in some countries to prevent infection in high-risk populations.

Q fever is a zoonotic disease caused by the bacterium Coxiella burnetii. It is characterized by acute or chronic flu-like symptoms, pneumonia, and hepatitis. The bacteria are primarily transmitted to humans through inhalation of contaminated dust or aerosols from infected animals such as cattle, sheep, and goats. Q fever can also be transmitted through consumption of unpasteurized milk or direct contact with infected animals. It is often asymptomatic or mildly symptomatic in animals but can cause severe disease in humans.

The acute form of Q fever typically presents with sudden onset of high fever, severe headache, fatigue, muscle pain, and cough. Some patients may also develop pneumonia or hepatitis. The chronic form of the disease is less common but more serious, often affecting people with compromised immune systems. Chronic Q fever can lead to endocarditis, an infection of the inner lining of the heart, which can be life-threatening if left untreated.

Diagnosis of Q fever typically involves a combination of clinical evaluation, serological testing, and PCR (polymerase chain reaction) assays. Treatment usually involves antibiotics such as doxycycline or fluoroquinolones for several weeks to months, depending on the severity and duration of the illness. Prevention measures include avoiding contact with infected animals, wearing protective clothing and masks when handling animal products, and pasteurizing milk before consumption.

Environmental pollutants are defined as any substances or energy (such as noise, heat, or light) that are present in the environment and can cause harm or discomfort to humans or other living organisms, or damage the natural ecosystems. These pollutants can come from a variety of sources, including industrial processes, transportation, agriculture, and household activities. They can be in the form of gases, liquids, solids, or radioactive materials, and can contaminate air, water, and soil. Examples include heavy metals, pesticides, volatile organic compounds (VOCs), particulate matter, and greenhouse gases.

It is important to note that the impact of environmental pollutants on human health and the environment can be acute (short-term) or chronic (long-term) and it depends on the type, concentration, duration and frequency of exposure. Some common effects of environmental pollutants include respiratory problems, cancer, neurological disorders, reproductive issues, and developmental delays in children.

It is important to monitor, control and reduce the emissions of these pollutants through regulations, technology advancements, and sustainable practices to protect human health and the environment.

Lyme disease is not a "medical definition" itself, but it is a medical condition named after the town of Lyme, Connecticut, where it was first identified in 1975. Medical definitions for this disease are provided by authoritative bodies such as the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC). According to the CDC, Lyme disease is a "infection caused by the bacterium Borrelia burgdorferi and is transmitted to humans through the bite of infected black-legged ticks."

The WHO defines Lyme borreliosis (LB), also known as Lyme disease, as "an infectious disease caused by spirochetes of the Borrelia burgdorferi sensu lato complex. It is transmitted to humans through the bite of infected Ixodes spp. ticks."

Both definitions highlight that Lyme disease is a bacterial infection spread by tick bites, specifically from black-legged ticks (Ixodes scapularis in the United States and Ixodes pacificus on the Pacific Coast) or deer ticks (Ixodes ricinus in Europe). The primary cause of the disease is the spirochete bacterium Borrelia burgdorferi.

Seroepidemiologic studies are a type of epidemiological study that measures the presence and levels of antibodies in a population's blood serum to investigate the prevalence, distribution, and transmission of infectious diseases. These studies help to identify patterns of infection and immunity within a population, which can inform public health policies and interventions.

Seroepidemiologic studies typically involve collecting blood samples from a representative sample of individuals in a population and testing them for the presence of antibodies against specific pathogens. The results are then analyzed to estimate the prevalence of infection and immunity within the population, as well as any factors associated with increased or decreased risk of infection.

These studies can provide valuable insights into the spread of infectious diseases, including emerging and re-emerging infections, and help to monitor the effectiveness of vaccination programs. Additionally, seroepidemiologic studies can also be used to investigate the transmission dynamics of infectious agents, such as identifying sources of infection or tracking the spread of antibiotic resistance.

I'm sorry for any confusion, but "geography" is not a term that has a medical definition. Geography is a field of study that deals with the location and distribution of physical and cultural features on Earth's surface, as well as how humans interact with and affect those features. It is not a concept that is typically used in a medical context. If you have any questions related to medicine or healthcare, I would be happy to try to help answer them for you!

Environmental exposure refers to the contact of an individual with any chemical, physical, or biological agent in the environment that can cause a harmful effect on health. These exposures can occur through various pathways such as inhalation, ingestion, or skin contact. Examples of environmental exposures include air pollution, water contamination, occupational chemicals, and allergens. The duration and level of exposure, as well as the susceptibility of the individual, can all contribute to the risk of developing an adverse health effect.

In epidemiology, the incidence of a disease is defined as the number of new cases of that disease within a specific population over a certain period of time. It is typically expressed as a rate, with the number of new cases in the numerator and the size of the population at risk in the denominator. Incidence provides information about the risk of developing a disease during a given time period and can be used to compare disease rates between different populations or to monitor trends in disease occurrence over time.

A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.

Medical Definition:

"Risk factors" are any attribute, characteristic or exposure of an individual that increases the likelihood of developing a disease or injury. They can be divided into modifiable and non-modifiable risk factors. Modifiable risk factors are those that can be changed through lifestyle choices or medical treatment, while non-modifiable risk factors are inherent traits such as age, gender, or genetic predisposition. Examples of modifiable risk factors include smoking, alcohol consumption, physical inactivity, and unhealthy diet, while non-modifiable risk factors include age, sex, and family history. It is important to note that having a risk factor does not guarantee that a person will develop the disease, but rather indicates an increased susceptibility.

  • The gross domestic product per capita in Slovakia was forecast to continuously increase between 2023 and 2028 by in total 7,829.2 U.S. dollars (+31.99 percent). (statista.com)
  • The world's largest per-capita car producer, Slovakia manufactured a total of 1.1 million cars in 2019, representing 43% of its total industrial output. (wikipedia.org)
  • Duration: 1 April 2022 - 31 March 2024 Country: Slovenia and Slovakia Community: Roma What is this programme about? (minorityrights.org)
  • Duration: 10 October 2017 - 31 March 2021 Countries: Bulgaria, Hungary, Poland, Slovakia Communities: Various What was this programme about? (minorityrights.org)
  • Slovakia became an independent state on 1 January 1993 after the peaceful dissolution of Czechoslovakia, sometimes known as the Velvet Divorce. (wikipedia.org)
  • Most foreign translations tend to stem from this newer form (Slovakia in English, Slowakei in German, Slovaquie in French, etc. (wikipedia.org)
  • BRATISLAVA, Slovakia - Slovakia's prosecutors have indicted four suspects for the slaying of an investigative reporter and his fiancee, a case that brought down the Slovak government. (nypost.com)
  • From the majestic Tatra Mountains to the charming capital city of Bratislava, Slovakia offers a diverse range of experiences for every type of traveler. (khaosanroad.com)
  • For references , please go to https://www.eea.europa.eu/themes/industry/industrial-pollution/industrial-pollution-country-profiles-2017/slovakia-industrial-pollution-profile-2017 or scan the QR code. (europa.eu)
  • Slovakia is overtaken by Albania, which was ranked number 66 at 14.03 Years and is followed by Romania with 13.84 Years. (nationmaster.com)
  • Slovakia is overtaken by Lithuania, which was ranked number 16 at 9,802 Full-Time Equivalent and is followed by New Zealand at 8,567.75 Full-Time Equivalent. (nationmaster.com)
  • Denmark, the Netherlands, and Finland lead the European Union in broadband penetration while Greece, Slovakia, and Poland trail according to a recent broadband survey by ECTA. (websiteoptimization.com)
  • Slovakia remains the largest per capita car producer in the world, with four major car producers and hundreds of suppliers. (state.gov)
  • Slovakia is a developed country with an advanced high-income economy. (wikipedia.org)
  • It is likely Slovakia will wait until the system is operational (the Ministry recommends to wait 3 years after beginning of operation with initiating the ratification process). (twobirds.com)
  • Slovakia joined both NATO and the EU in the spring of 2004. (travelblog.org)
  • Hockey players from Russia and Slovakia were involved in a brutal mass-brawl, forcing cops to be called to the rink on Saturday night. (nypost.com)
  • In a written statement today, SE spokeswoman Alena Melicharkova said the team of experts, with representatives from Austria, Germany, Russia, Switzerland and the U.S., is expected to stay in Slovakia for at least three days. (rferl.org)
  • Approximately 54.7 % of the total production of 27,149 GWh of electricity in Slovakia was obtained from nuclear power stations, 21 % from conventional power stations, 14.4 % from hydro stations and 8.9 % from renewable sources. (trade.gov)
  • European Union (EU) officials, meeting Slovakia official last week in Luxembourg, issued a statement, insisting that nuclear safety in Slovakia be strengthened. (rferl.org)
  • Slovakia is an attractive destination for foreign direct investment (FDI), with a favorable geographic location in the heart of Europe and an investment-friendly regulatory environment. (state.gov)
  • We are all experienced in Slovakia, but also in Europe. (gls-group.eu)
  • Slovakia is a hidden gem nestled in the heart of Europe, boasting a rich history, stunning natural beauty, and a vibrant culture. (khaosanroad.com)
  • Slovakia is a small, open, export-oriented economy with a population of 5.5 million people. (state.gov)
  • Slovakia currently imports about 15 percent of its electricity needs. (rferl.org)
  • Vaccine introduction status in Slovakia over time. (who.int)
  • For references , please go to https://www.eea.europa.eu/publications/many-eu-member-states/slovakia or scan the QR code. (europa.eu)
  • A woman performed oral sex on a gas station robber in Slovakia - distracting and delaying him until police arrived, according to a report. (nypost.com)
  • Slovakia has been plunged into political crisis by the killing of an investigative journalist who wrote about links between the government and Italy's notorious 'Ndrangheta mafia group. (rferl.org)
  • Since 2014, Slovakia Number of Physicians Employed in Hospitals jumped by 0.9% year on year. (nationmaster.com)
  • Implementation of the Unified Patent Agreement in Slovakia would not require to adopt/repeal any legal regulation. (twobirds.com)
  • Compared to its market share in other Central European countries, U.S. market share in Slovakia is relatively low. (trade.gov)
  • Slovakia is also home to numerous UNESCO World Heritage sites, including the Spiš Castle and the wooden churches of the Carpathian region. (khaosanroad.com)
  • Biomass has the largest technical potential 11,200 GWh per year, which is approximately 40 % of the total domestic production of energy in Slovakia. (trade.gov)
  • The technical potential of solar energy has been estimated at 5,200 GWh annually, which is about 20 % of the total technical potential of renewable power sources in Slovakia. (trade.gov)
  • Slovakia adopted a new clean energy and co-generation support scheme - introduced by an amendment to the Act on Support of Renewable Energy Sources and High Efficiency Combined Heat and Power (Act No. 309/2009 Coll). (trade.gov)
  • But, officials have said Slovakia will no longer have to import energy, once Mochovce's two reactors come into service. (rferl.org)
  • An 11-year-old Ukrainian boy traveled 600 miles to Slovakia on his own to escape the Russians - with a phone number scrawled on his hand. (nypost.com)
  • The total potential of renewable sources that Slovakia plans to utilize is approximately 27,000 GWh per year. (trade.gov)
  • Geothermal potential in Slovakia is approximately 6,300 GWh per year, but currently only 145 GWh are being used, which is only 2.6 % of the total potential. (trade.gov)
  • Since 2014, Slovakia School Life Expectancy for Men was down by 0.3% year on year. (nationmaster.com)
  • Slovakia struggled to work the ball out of the corner and Ireland's pressure saw the play worked along the edge of the box where O'Sullivan played McCabe into space. (rte.ie)
  • KEZMAROK, Slovakia - Monika Krcova did not want to follow the official guidelines and remain in the hospital in Slovakia for four days after her third baby's birth. (nypost.com)
  • Slovakia will very likely want to see and observe how the system functions before it ratifies. (twobirds.com)
  • Coming from Slovakia, I was part of the generation of students who was able to take part in Erasmus programs and broadened my horizons though the travel opportunities that were offered to me. (lu.se)
  • The Republic of Ireland battled back for a hard-fought 1-1 draw in their World Cup qualifier against Slovakia at Tallaght Stadium. (rte.ie)
  • Police in Slovakia alerted Austrian authorities in the summer that "suspicious people" had traveled to the country to try to buy high-power ammo a few months before the deadly attack. (nypost.com)
  • Alkaptonuria is more common in certain areas of Slovakia (where it has an incidence of about 1 in 19,000 people) and in the Dominican Republic. (medlineplus.gov)
  • Biden will survey a checkpoint at a border crossing in Vyšné Nemecké, Slovakia, where Ukrainian refugees receive basic assistance from humanitarian and Slovakian aid workers. (nypost.com)

No images available that match "slovakia"