AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
SleepSleep, REMSleep DisordersSleep Apnea, ObstructiveSleep Apnea SyndromesSleep Initiation and Maintenance DisordersPolysomnographyWakefulnessElectroencephalographyActigraphyArousalSleep Apnea, CentralCircadian RhythmDisorders of Excessive SomnolenceSleep BruxismSleep Disorders, IntrinsicElectrooculographySleep Medicine SpecialtySleep Arousal DisordersSnoringNarcolepsyDelta RhythmSleep ParalysisDreamsREM Sleep Behavior DisorderNocturnal Myoclonus SyndromeContinuous Positive Airway PressureElectromyographyQuestionnairesTime FactorsFatigueHypnotics and SedativesHabitsMelatoninSeverity of Illness IndexCataplexyRestless Legs SyndromeAnalysis of VarianceSleep Phase ChronotherapyRespirationBody TemperatureCross-Sectional StudiesMandibular AdvancementSomnambulismAdenoidectomyTonsillectomyPharynxUvulaHomeostasisPonsPalate, SoftBrain WavesActivity CyclesAzabicyclo CompoundsRisk FactorsComorbidityChronobiology DisordersPositive-Pressure RespirationPrevalenceBody Mass IndexMonitoring, AmbulatoryCross-Over StudiesPharyngeal MusclesBrainRespiratory Mechanics
Sleep: A readily reversible suspension of sensorimotor interaction with the environment, usually associated with recumbency and immobility.Sleep, REM: A stage of sleep characterized by rapid movements of the eye and low voltage fast pattern EEG. It is usually associated with dreaming.Sleep Disorders: Conditions characterized by disturbances of usual sleep patterns or behaviors. Sleep disorders may be divided into three major categories: DYSSOMNIAS (i.e. disorders characterized by insomnia or hypersomnia), PARASOMNIAS (abnormal sleep behaviors), and sleep disorders secondary to medical or psychiatric disorders. (From Thorpy, Sleep Disorders Medicine, 1994, p187)Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.Polysomnography: Simultaneous and continuous monitoring of several parameters during sleep to study normal and abnormal sleep. The study includes monitoring of brain waves, to assess sleep stages, and other physiological variables such as breathing, eye movements, and blood oxygen levels which exhibit a disrupted pattern with sleep disturbances.Wakefulness: A state in which there is an enhanced potential for sensitivity and an efficient responsiveness to external stimuli.Electroencephalography: Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.Actigraphy: The measurement and recording of MOTOR ACTIVITY to assess rest/activity cycles.Arousal: Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.Sleep Apnea, Central: A condition associated with multiple episodes of sleep apnea which are distinguished from obstructive sleep apnea (SLEEP APNEA, OBSTRUCTIVE) by the complete cessation of efforts to breathe. This disorder is associated with dysfunction of central nervous system centers that regulate respiration.Circadian Rhythm: The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs and stimuli, hormone secretion, sleeping, and feeding.Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)Sleep Bruxism: A sleep disorder characterized by grinding and clenching of the teeth and forceful lateral or protrusive jaw movements. Sleep bruxism may be associated with TOOTH INJURIES; TEMPOROMANDIBULAR JOINT DISORDERS; sleep disturbances; and other conditions.Sleep Disorders, Intrinsic: Dyssomnias (i.e., insomnias or hypersomnias) associated with dysfunction of internal sleep mechanisms or secondary to a sleep-related medical disorder (e.g., sleep apnea, post-traumatic sleep disorders, etc.). (From Thorpy, Sleep Disorders Medicine, 1994, p187)Electrooculography: Recording of the average amplitude of the resting potential arising between the cornea and the retina in light and dark adaptation as the eyes turn a standard distance to the right and the left. The increase in potential with light adaptation is used to evaluate the condition of the retinal pigment epithelium.Sleep Medicine Specialty: A medical specialty concerned with the diagnosis and treatment of SLEEP WAKE DISORDERS and their causes.Sleep Arousal Disorders: Sleep disorders characterized by impaired arousal from the deeper stages of sleep (generally stage III or IV sleep).Snoring: Rough, noisy breathing during sleep, due to vibration of the uvula and soft palate.Narcolepsy: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)Delta Rhythm: Brain waves seen on EEG characterized by a high amplitude and a frequency of 4 Hz and below. They are considered the "deep sleep waves" observed during sleep in dreamless states, infancy, and in some brain disorders.Sleep Paralysis: A common condition characterized by transient partial or total paralysis of skeletal muscles and areflexia that occurs upon awakening from sleep or less often while falling asleep. Stimuli such as touch or sound may terminate the episode, which usually has a duration of seconds to minutes. This condition may occur in normal subjects or be associated with NARCOLEPSY; CATAPLEXY; and hypnagogic HALLUCINATIONS. The pathophysiology of this condition is closely related to the normal hypotonia that occur during REM sleep. (From Adv Neurol 1995;67:245-271)Dreams: A series of thoughts, images, or emotions occurring during sleep which are dissociated from the usual stream of consciousness of the waking state.REM Sleep Behavior Disorder: A disorder characterized by episodes of vigorous and often violent motor activity during REM sleep (SLEEP, REM). The affected individual may inflict self injury or harm others, and is difficult to awaken from this condition. Episodes are usually followed by a vivid recollection of a dream that is consistent with the aggressive behavior. This condition primarily affects adult males. (From Adams et al., Principles of Neurology, 6th ed, p393)Nocturnal Myoclonus Syndrome: Excessive periodic leg movements during sleep that cause micro-arousals and interfere with the maintenance of sleep. This condition induces a state of relative sleep deprivation which manifests as excessive daytime hypersomnolence. The movements are characterized by repetitive contractions of the tibialis anterior muscle, extension of the toe, and intermittent flexion of the hip, knee and ankle. (Adams et al., Principles of Neurology, 6th ed, p387)Continuous Positive Airway Pressure: A technique of respiratory therapy, in either spontaneously breathing or mechanically ventilated patients, in which airway pressure is maintained above atmospheric pressure throughout the respiratory cycle by pressurization of the ventilatory circuit. (On-Line Medical Dictionary [Internet]. Newcastle upon Tyne(UK): The University Dept. of Medical Oncology: The CancerWEB Project; c1997-2003 [cited 2003 Apr 17]. Available from: http://cancerweb.ncl.ac.uk/omd/)Electromyography: Recording of the changes in electric potential of muscle by means of surface or needle electrodes.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.Hypnotics and Sedatives: Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.Habits: Acquired or learned responses which are regularly manifested.Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Cataplexy: A condition characterized by transient weakness or paralysis of somatic musculature triggered by an emotional stimulus or physical exertion. Cataplexy is frequently associated with NARCOLEPSY. During a cataplectic attack, there is a marked reduction in muscle tone similar to the normal physiologic hypotonia that accompanies rapid eye movement sleep (SLEEP, REM). (From Adams et al., Principles of Neurology, 6th ed, p396)Restless Legs Syndrome: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Sleep Phase Chronotherapy: A progressive advance or delay of bedtime until the desired bedtime is achieved.Respiration: The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).Body Temperature: The measure of the level of heat of a human or animal.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Mandibular Advancement: Moving a retruded mandible forward to a normal position. It is commonly performed for malocclusion and retrognathia. (From Jablonski's Dictionary of Dentistry, 1992)Somnambulism: A parasomnia characterized by a partial arousal that occurs during stage IV of non-REM sleep. Affected individuals exhibit semipurposeful behaviors such as ambulation and are difficult to fully awaken. Children are primarily affected, with a peak age range of 4-6 years.Adenoidectomy: Excision of the adenoids. (Dorland, 28th ed)Tonsillectomy: Surgical removal of a tonsil or tonsils. (Dorland, 28th ed)Pharynx: A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx).Uvula: A fleshy extension at the back of the soft palate that hangs above the opening of the throat.Homeostasis: The processes whereby the internal environment of an organism tends to remain balanced and stable.Pons: The front part of the hindbrain (RHOMBENCEPHALON) that lies between the MEDULLA and the midbrain (MESENCEPHALON) ventral to the cerebellum. It is composed of two parts, the dorsal and the ventral. The pons serves as a relay station for neural pathways between the CEREBELLUM to the CEREBRUM.Palate, Soft: A movable fold suspended from the posterior border of the hard palate. The uvula hangs from the middle of the lower border.Brain Waves: Wave-like oscillations of electric potential between parts of the brain recorded by EEG.Activity Cycles: Bouts of physical irritability or movement alternating with periods of quiescence. It includes biochemical activity and hormonal activity which may be cellular. These cycles are shorter than 24 hours and include sleep-wakefulness cycles and the periodic activation of the digestive system.Azabicyclo Compounds: Bicyclic bridged compounds that contain a nitrogen which has three bonds. The nomenclature indicates the number of atoms in each path around the rings, such as [2.2.2] for three equal length paths. Some members are TROPANES and BETA LACTAMS.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Chronobiology Disorders: Disruptions of the rhythmic cycle of bodily functions or activities.Positive-Pressure Respiration: A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Body Mass Index: An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)Monitoring, Ambulatory: The use of electronic equipment to observe or record physiologic processes while the patient undergoes normal daily activities.Cross-Over Studies: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)Pharyngeal Muscles: The muscles of the PHARYNX are voluntary muscles arranged in two layers. The external circular layer consists of three constrictors (superior, middle, and inferior). The internal longitudinal layer consists of the palatopharyngeus, the salpingopharyngeus, and the stylopharyngeus. During swallowing, the outer layer constricts the pharyngeal wall and the inner layer elevates pharynx and LARYNX.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Respiratory Mechanics: The physical or mechanical action of the LUNGS; DIAPHRAGM; RIBS; and CHEST WALL during respiration. It includes airflow, lung volume, neural and reflex controls, mechanoreceptors, breathing patterns, etc.

Quantitative aspects in the assessment of liver injury. (1/4912)

Liver function data are usually difficult to use in their original form when one wishes to compare the hepatotoxic properties of several chemical substances. However, procedures are available for the conversion of liver function data into quantal responses. These permit the elaboration of dose-response lines for the substances in question, the calculation of median effective doses and the statistical analysis of differences in liver-damaging potency. These same procedures can be utilized for estimating the relative hazard involved if one compares the liver-damaging potency to the median effective dose for some other pharmacologie parameter. Alterations in hepatic triglycerides, lipid peroxidation, and the activities of various hepatic enzymes can also be quantitiated in a dose-related manner. This permits the selection of equitoxic doses required for certain comparative studies and the selection of doses in chemical interaction studies. The quantitative problems involved in low-frequency adverse reactions and the difficulty these present in the detection of liver injury in laboratory animals are discussed.  (+info)

Physiological properties of raphe magnus neurons during sleep and waking. (2/4912)

Neurons in the medullary raphe magnus (RM) that are important in the descending modulation of nociceptive transmission are classified by their response to noxious tail heat as ON, OFF, or NEUTRAL cells. Experiments in anesthetized animals demonstrate that RM ON cells facilitate and OFF cells inhibit nociceptive transmission. Yet little is known of the physiology of these cells in the unanesthetized animal. The first aim of the present experiments was to determine whether cells with ON- and OFF-like responses to noxious heat exist in the unanesthetized rat. Second, to determine if RM cells have state-dependent discharge, the activity of RM neurons was recorded during waking and sleeping states. Noxious heat applied during waking and slow wave sleep excited one group of cells (ON-U) in unanesthetized rats. Other cells were inhibited by noxious heat (OFF-U) applied during waking and slow wave sleep states in unanesthetized rats. NEUTRAL-U cells did not respond to noxious thermal stimulation applied during either slow wave sleep or waking. ON-U and OFF-U cells were more likely to respond to noxious heat during slow wave sleep than during waking and were least likely to respond when the animal was eating or drinking. Although RM cells rarely respond to innocuous stimulation applied during anesthesia, ON-U and OFF-U cells were excited and inhibited, respectively, by innocuous somatosensory stimulation in the unanesthetized rat. The spontaneous activity of >90% of the RM neurons recorded in the unanesthetized rat was influenced by behavioral state. OFF-U cells discharged sporadically during waking but were continuously active during slow wave sleep. By contrast, ON-U and NEUTRAL-U cells discharged in bursts during waking and either ceased to discharge entirely or discharged at a low rate during slow wave sleep. We suggest that OFF cell discharge functions to suppress pain-evoked reactions during sleep, whereas ON cell discharge facilitates pain-evoked responses during waking.  (+info)

Arousal from sleep shortens sympathetic burst latency in humans. (3/4912)

1. Bursts of sympathetic activity in muscle nerves are phase-locked to the cardiac cycle by the sinoaortic baroreflexes. Acoustic arousal from non-rapid eye movement (NREM) sleep reduces the normally invariant interval between the R-wave of the electrocardiogram (ECG) and the peak of the corresponding sympathetic burst; however, the effects of other forms of sleep disruption (i.e. spontaneous arousals and apnoea-induced arousals) on this temporal relationship are unknown. 2. We simultaneously recorded muscle sympathetic nerve activity in the peroneal nerve (intraneural electrodes) and the ECG (surface electrodes) in seven healthy humans and three patients with sleep apnoea syndrome during NREM sleep. 3. In seven subjects, burst latencies were shortened subsequent to spontaneous K complexes (1.297 +/- 0.024 s, mean +/- s. e.m.) and spontaneous arousals (1.268 +/- 0.044 s) compared with latencies during periods of stable NREM sleep (1.369 +/- 0.023 s). In six subjects who demonstrated spontaneous apnoeas during sleep, apnoea per se did not alter burst latency relative to sleep with stable electroencephalogram (EEG) and breathing (1.313 +/- 0.038 vs. 1.342 +/- 0.026 s); however, following apnoea-induced EEG perturbations, burst latencies were reduced (1.214 +/- 0.034 s). 4. Arousal-induced reduction in sympathetic burst latency may reflect a temporary diminution of baroreflex buffering of sympathetic outflow. If so, the magnitude of arterial pressure perturbations during sleep (e.g. those caused by sleep disordered breathing and periodic leg movements) may be augmented by arousal.  (+info)

Effects of truss mattress upon sleep and bed climate. (4/4912)

The purpose of this study was to examine the effects of a truss mattress upon sleep and bed climate. The truss mattress which has been designed to decrease the pressure and bed climate humidity was tested. Six healthy female volunteers with a mean age of 23.3 years, served as subjects. The experiment was carried out under two conditions: a truss mattress (T) and a futon (F) (Japanese bedding). The ambient temperature and relative humidity were controlled at 19-20 degrees C, and RH 50-60% respectively. Sleep was monitored by an EEG machine and the rectal temperature, skin temperature and bed climate were also measured continuously. Subjective evaluations of bed and sleep were obtained before and after the recording sessions. No significant difference was observed in the sleep parameters and time spent in each sleep stage. Rectal temperature was significantly lower in T than F. Although there was no significant difference in bed climate over the T/F, the temperature under T/F was significantly higher in T. No significant difference was observed in subjective sleep evaluation. The subjective feeling of the mattress was significantly warmer in F than T before sleep. These results suggest that although T does not disturb the sleep parameters and the bed climate is maintained at the same level as with F, it may affect rectal temperature which can be due to low thermal insulation.  (+info)

Effect of working hours on cardiovascular-autonomic nervous functions in engineers in an electronics manufacturing company. (5/4912)

A field survey of 147 engineers (23-49 years) in an electronics manufacturing company was conducted to investigate the effect of working hours on cardiovascular-autonomic nervous functions (urinary catecholamines, heart rate variability and blood pressure). The subjects were divided into 3 groups by age: 23-29 (n = 49), 30-39 (n = 74) and 40-49 (n = 24) year groups. Subjects in each age group were further divided into shorter (SWH) and longer (LWH) working hour subgroups according to the median of weekly working hours. In the 30-39 year group, urinary noradrenaline in the afternoon for LWH was significantly lower than that for SWH and a similar tendency was found in the LF/HF ratio of heart rate variability at rest. Because these two autonomic nervous indices are related to sympathetic nervous activity, the findings suggested that sympathetic nervous activity for LWH was lower than that for SWH in the 30-39 year group. Furthermore, there were significant relationships both between long working hours and short sleeping hours, and between short sleeping hours and high complaint rates of "drowsiness and dullness" in the morning in this age group. Summarizing these results, it appeared that long working hours might lower sympathetic nervous activity due to chronic sleep deprivation.  (+info)

Ethanol as a hypnotic in insomniacs: self administration and effects on sleep and mood. (6/4912)

The purpose of this study was to assess the effects of low ethanol doses on sleep and mood and to assess its reinforcing effects used as a hypnotic. Twenty healthy adults, aged 21-45 yrs, all moderate social drinkers, were studied: eleven subjects had insomnia and nine were normal sleepers, as documented by clinical polysomnography. On two sampling nights each, ethanol (0.5 g/kg) or placebo was administered before sleep in color-coded cups presented in three doses (0.2, 0.2, and 0.1 g/kg) separated by 15 min. On three subsequent nights subjects chose their preferred presleep beverage (0.2 g/kg ethanol or placebo) based on cup color and were given an opportunity for 3 additional refills (0.2 g/kg each) of the chosen beverage at 15 min intervals, yielding a total possible dose of 0.8 g/kg. Insomniacs chose ethanol 67% of nights and normals 22%. Insomniacs chose significantly more ethanol refills than normals for an average nightly dose of 0.45 g/kg and normals took significantly more placebo refills. On the sampling nights 0.5 g/kg ethanol reduced REM sleep for both groups for the 8-hr sleep period and in insomniacs increased stage 3-4 sleep and reduced stage 1 sleep during the first half of the night to the level seen in the normals. Other sleep variables were not altered in either group or halves of the night. Presleep improvements in the Profile of Mood States tension and concentration factors were also associated with ethanol administration. Thus, acutely, both sleep and mood effects appear to be associated with the reinforcing effects of ethanol as a hypnotic for insomniacs.  (+info)

Intrapreoptic microinjection of GHRH or its antagonist alters sleep in rats. (7/4912)

Previous reports indicate that growth hormone-releasing hormone (GHRH) is involved in sleep regulation. The site of action mediating the nonrapid eye movement sleep (NREMS)-promoting effects of GHRH is not known, but it is independent from the pituitary. GHRH (0.001, 0. 01, and 0.1 nmol/kg) or a competitive antagonist of GHRH (0.003, 0.3, and 14 nmol/kg) was microinjected into the preoptic area, and the sleep-wake activity was recorded for 23 hr after injection in rats. GHRH elicited dose-dependent increases in the duration and in the intensity of NREMS compared with that in control records after intrapreoptic injection of physiological saline. The antagonist decreased the duration and intensity of NREMS and prolonged sleep latency. Consistent alterations in rapid eye movement sleep (REMS) and in brain temperature were not found. The GHRH antagonist also attenuated the enhancements in NREMS elicited by 3 hr of sleep deprivation. Histological verification of the injection sites showed that the majority of the effective injections were in the preoptic area and the diagonal band of Broca. The results indicate that the preoptic area mediates the sleep-promoting activity of GHRH.  (+info)

Energy intake, not energy output, is a determinant of body size in infants. (8/4912)

BACKGROUND: It has been proposed that the primary determinants of body weight at 1 y of age are genetic background, as represented by parental obesity, and low total energy expenditure. OBJECTIVE: The objective was to determine the relative contributions of genetic background and energy intake and expenditure as determinants of body weight at 1 y of age. DESIGN: Forty infants of obese and 38 infants of lean mothers, half boys and half girls, were assessed at 3 mo of age for 10 risk factors for obesity: sex, risk group (obese or nonobese mothers), maternal and paternal body mass index, body weight, feeding mode (breast, bottle, or both), 3-d energy intake, nutritive sucking behavior during a test meal, total energy expenditure, sleeping energy expenditure, and interactions among them. RESULTS: The only difference between risk groups at baseline was that the high-risk group sucked more vigorously during the test meal. Four measures accounted for 62% of the variability in weight at 12 mo: 3-mo weight (41%, P = 0.0001), nutritive sucking behavior (9%, P = 0.0002), 3-d food intake (8%, P = 0.0002), and male sex (3%, P = 0.05). Food intake and sucking behavior at 3 mo accounted for similar amounts of variability in weight-for-length, body fat, fat-free mass, and skinfold thickness at 12 mo. Contrary to expectations, neither total nor sleeping energy expenditure at 3 mo nor maternal obesity contributed to measures of body size at 12 mo. CONCLUSIONS: Energy intake contributes significantly to measures of body weight and composition at 1 y of age; parental obesity and energy expenditure do not.  (+info)

Sleep in women : Normal values for sleep stages and position and the effect of age, obesity, sleep apnea, smoking, alcohol and...Sleep in women : Normal values for sleep stages and position and the effect of age, obesity, sleep apnea, smoking, alcohol and...
OBJECTIVES: To define normal values for total sleep time, sleep latency, sleep efficiency, sleep stages and sleeping positions in women and to investigate how sleep is affected by age, obesity, sleep apnea, smoking, alcohol dependency and hypertension. METHODS: In a population-based study, 400 Swedish women aged 20-70 years with over-sampling of snorers were investigated using overnight in-home polysomnography. All results are weighted. RESULTS: The mean normal total sleep time was 392 min, sleep latency 22 min and sleep efficiency 82%. Women spent 31 min in sleep stage 1, 244 min in stage 2, 41 min in stage 3/4 and 76 min in rapid eye movement (REM) sleep. They spent 41% of their sleep time in the supine position, 50% in the lateral position and 9% in the prone position. Multivariate analyses revealed that sleep efficiency was lower in older women and in women with hypertension. Sleep latency was short in women with severe sleep apnea and long in smokers, alcohol-dependent and hypertensive ...
Late sleep - definition of late sleep by The Free DictionaryLate sleep - definition of late sleep by The Free Dictionary
Define late sleep. late sleep synonyms, late sleep pronunciation, late sleep translation, English dictionary definition of late sleep. late sleep. Translations. Spanish / Español: quedarse en cama. French / Français: grasse matinée. German / Deutsch: Ausschlafen. + 18 more languages
Poor sleep quality and obstructive sleep apnea in patients with GERD and Barretts esophagus<...Poor sleep quality and obstructive sleep apnea in patients with GERD and Barrett's esophagus<...
TY - JOUR. T1 - Poor sleep quality and obstructive sleep apnea in patients with GERD and Barretts esophagus. AU - Vela, M. F.. AU - Kramer, J. R.. AU - Richardson, P. A.. AU - Dodge, R.. AU - El-Serag, H. B.. PY - 2014/3/1. Y1 - 2014/3/1. N2 - Background: Gastroesophageal reflux disease (GERD) reduces sleep quality. Whether Barretts esophagus (BE) affects sleep differently is unknown. Obstructive sleep apnea (OSA) often coexists with GERD and may disrupt sleep; whether GERD reduces sleep quality independently of OSA is unknown. Our aims were to compare the effect of GERD and BE on sleep quality, and assess the impact of OSA on this association. Methods: Validated questionnaires for GERD symptoms, sleep quality, and OSA risk were prospectively administered to subjects undergoing upper endoscopy. GERD was defined by erosive esophagitis and/or reflux symptoms ,1/week. BE was defined histologically. Controls had normal endoscopy and were asymptomatic. Poor sleep quality was defined by a Pittsburgh ...
Sleep duration and chronic kidney disease: The Korean Genome and Epidemiology Study (KoGES)-Kangwha studySleep duration and chronic kidney disease: The Korean Genome and Epidemiology Study (KoGES)-Kangwha study
We investigated the associations between sleep duration and CKD in a Korean adult population. Herein, sleeping more than 9 hours was significantly associated with CKD in women; however, sleep duration was not significantly associated with CKD in men.. In recent decades, the average sleep duration in most individuals has reduced, and many studies have investigated shorter sleep durations and their effects on health. In particular, the average sleep duration of Koreans was 7 hours and 49 minutes per day, which was the lowest among 18 OECD (Organisation for Economic Co-operation and Development) member countries [19]. Notwithstanding, epidemiological evidence of associations between sleep duration and CKD is insufficient. Previous studies reported that sleeping less than 5 hours was associated with proteinuria in the Japanese population [8,20] and higher risk of CKD among the shift workers [13]. More recently, an increasing number of studies have linked prolonged sleep duration with poor health ...
For a good nights sleep | Beauty and Personal GroomingFor a good night's sleep | Beauty and Personal Grooming
Some of the major health benefits of good sleep are as below -. A proper sleep is necessary for good eye sight (vision). If you do not sleep properly at night then you will have defective vision. Emaciation, weakness, impotency, sterility, lack of knowledge and death may be result of poor sleep. A good night sleep strengthens the presence of your mind and consciousness. It makes you feel energized and physically more alert. It enhances your memory and learning capacity. Getting adequate sleep will help you remember and process things better. Good sleep strengthens your immune system and makes you less prone to various illnesses. It reduces stress, tension and anxiety. A proper sleep allows your body to rest and relax. When your body lacks sleep it goes into a state of stress. Good night sleep helps to lose weight. Sleep deficient individuals are more likely to be overweight or obese. Good night sleep keeps your heart healthy. Lack of proper sleep has been associated with increasing blood ...
For a good nights sleep | Beauty and Personal GroomingFor a good night's sleep | Beauty and Personal Grooming
Some of the major health benefits of good sleep are as below -. A proper sleep is necessary for good eye sight (vision). If you do not sleep properly at night then you will have defective vision. Emaciation, weakness, impotency, sterility, lack of knowledge and death may be result of poor sleep. A good night sleep strengthens the presence of your mind and consciousness. It makes you feel energized and physically more alert. It enhances your memory and learning capacity. Getting adequate sleep will help you remember and process things better. Good sleep strengthens your immune system and makes you less prone to various illnesses. It reduces stress, tension and anxiety. A proper sleep allows your body to rest and relax. When your body lacks sleep it goes into a state of stress. Good night sleep helps to lose weight. Sleep deficient individuals are more likely to be overweight or obese. Good night sleep keeps your heart healthy. Lack of proper sleep has been associated with increasing blood ...
Effects of sleep apnea and kidney dysfunction on objective sleep quality in nondialyzed patients with chronic kidney disease:...Effects of sleep apnea and kidney dysfunction on objective sleep quality in nondialyzed patients with chronic kidney disease:...
STUDY OBJECTIVES: Patients with chronic kidney disease (CKD) often report poor sleep quality, but they commonly exhibit OSA. The aim of this study was to evaluate the influence of OSA severity and of estimated glomerular filtration rate impairment on objective sleep quality in nondialyzed patients with CKD, defined as an estimated glomerular filtration rate <60 mL/min/1.73m². METHODS: Polysomnographic sleep characteristics were compared between patients with (n = 430) and without CKD (n = 6,639) in the European Sleep Apnea Database cohort. Comparisons were repeated in 375 patients with CKD and 375 control patients without CKD matched for sleep center, age, sex, and AHI, and in 310 matched CKD and non-CKD patients without psychiatric disturbances. RESULTS: Among all patients with and without CKD, total sleep time was similar but sleep stage N1 (median 8.7% [IQR 4.8-18.0] vs 6.7% [3.6-12.7], respectively) and sleep stage R (12.6% [6.8-17.7] vs 14.2% [8.8-19.8], respectively) significantly ...
Examining the Biological Factors That Affect Sleep Duration - Full Text View - ClinicalTrials.govExamining the Biological Factors That Affect Sleep Duration - Full Text View - ClinicalTrials.gov
The amount of sleep people require depends on many factors, including age, but experts agree that most adults need 7 to 8 hours of sleep a night. People who sleep for shorter or longer amounts of time may be at risk of developing memory problems, heart disease, obesity, and diabetes. The duration and timing of sleep are regulated by an interaction between the circadian pacemaker, or biological clock, and the sleep homeostat, which is an internal account of the amount of sleep a person has received recently. It is unknown whether there is a biological or genetic basis for the amount of sleep a person needs. This inpatient study will examine two extreme sleep groups: short sleepers who sleep 6.5 or less hours a night and long sleepers who sleep 9 or more hours a night. Participants will be exposed to identical sleep opportunities and living conditions. Using hormone analysis to examine participants circadian rhythms, researchers will evaluate the biological differences that people undergo during ...
Sleep Science - Subjective sleep quality, unstimulated sexual arousal, and sexual frequencySleep Science - Subjective sleep quality, unstimulated sexual arousal, and sexual frequency
DISCUSSION. The present study confirmed that poorer subjective sleep quality is related to greater unstimulated sexual arousal, and that this relation was mostly driven by men with higher T levels and women with higher T levels not taking oral contraception. These findings extend previous ones showing that 1) severity of womens subjective sleep problems correlated with greater fantasy-induced subjective sexual arousal25, 2) perceived genital arousal was greater, when the duration of sleep was shorter in the previous night26, and 3) sleep deprivation in men increased erections in response to erotica23 and visual attention to images of women24. Our findings are also consistent with studies in male rats showing that unstimulated erections are facilitated by REM sleep deprivation11,12, a consequence of general sleep deprivation.. As predicted, severity of sleep problems correlated with unstimulated arousal only in the male and female groups with higher T levels. The facilitating role of T in ...
Sleep Science - Subjective sleep quality, unstimulated sexual arousal, and sexual frequencySleep Science - Subjective sleep quality, unstimulated sexual arousal, and sexual frequency
DISCUSSION. The present study confirmed that poorer subjective sleep quality is related to greater unstimulated sexual arousal, and that this relation was mostly driven by men with higher T levels and women with higher T levels not taking oral contraception. These findings extend previous ones showing that 1) severity of womens subjective sleep problems correlated with greater fantasy-induced subjective sexual arousal25, 2) perceived genital arousal was greater, when the duration of sleep was shorter in the previous night26, and 3) sleep deprivation in men increased erections in response to erotica23 and visual attention to images of women24. Our findings are also consistent with studies in male rats showing that unstimulated erections are facilitated by REM sleep deprivation11,12, a consequence of general sleep deprivation.. As predicted, severity of sleep problems correlated with unstimulated arousal only in the male and female groups with higher T levels. The facilitating role of T in ...
Sustained mental workload does not affect subsequent sleep intensity - De Bruin - 2002 - Journal of Sleep Research - Wiley...Sustained mental workload does not affect subsequent sleep intensity - De Bruin - 2002 - Journal of Sleep Research - Wiley...
Our experiments aimed to investigate whether different degrees of mental activity have a distinct effect on recovery processes during subsequent sleep. Sleep EEGs of 13 subjects, experiencing different degrees of mental activity, were scored visually. Also, the amount of SWA in the sleep EEG was calculated. The results indicate that light and heavy mental activity do not differentially affect sleep stages except for wakefulness after sleep onset. Subjects were less often awake shortly after sleep onset following heavy workload than after light mental activity. However, SWA, an indicator of sleep depth, did not reveal any difference between the light (A) and heavy condition (B). Neither the total amount of SWA expressed during the night, nor the amount of SWA in the first 120 min of NREM sleep, when recovery processes supposedly peak, showed a difference between the conditions. Even when the time course of SWA during sleep was studied in detail, the nights following light and heavy mental ...
SNORING/SLEEP APNOEA | Family Dental On CollinsSNORING/SLEEP APNOEA | Family Dental On Collins
We suggest patients to do overnight sleep studies to diagnose sleep disorders such as sleep apnoea. The sleep study will determine the level of severity of sleep apnoea.. Other sleep disorders can be diagnosed through sleep study such as restless leg syndrome and insomnia.. The sleep study can be done in the hospital or in the home. The home sleep study gives patients the comfort of sleeping in a natural environment. However, in some complex cases we suggest the patient to do an overnight sleep test in a hospital.. After analysing the data by a sleep physician, based on the degree of sleep apnea we suggest the sleep appliance or CPAP machine.. ...
Factors responsible for poor sleep quality in patients with chronic obstructive pulmonary disease | BMC Pulmonary Medicine |...Factors responsible for poor sleep quality in patients with chronic obstructive pulmonary disease | BMC Pulmonary Medicine |...
Our study demonstrated that 53 % of patients with COPD in our cohort had poor sleep quality (PSQI score , 5). A high prevalence of poor sleep quality in patients with COPD has been reported in previous studies [1, 2, 8]. In a recent real-world study, 78 % of patients with COPD reported night time disturbances as measured by the Jenkins Sleep Questionnaire [21]. In a telephone study, Ohayon reported COPD subjects had higher insomnia symptoms than non-COPD subjects (48.1 versus 27.6 % respectively) [22].. Our study also confirmed sleep disturbances, as well as cough and dyspnea, as major concerns in patients with COPD. Some researchers suggest that poor sleep quality might result in cognitive dysfunction, depression, anxiety, poor survival and poor quality of life [7]. Determining which factors are associated with sleep disturbances in patients with COPD may improve their treatment strategy.. A high prevalence of sleep symptoms among patients with COPD was discovered approximately thirty years ago ...
Sleepiness, quality of life, and sleep maintenance in REM versus non-REM sleep-disordered breathing<...Sleepiness, quality of life, and sleep maintenance in REM versus non-REM sleep-disordered breathing<...
TY - JOUR. T1 - Sleepiness, quality of life, and sleep maintenance in REM versus non-REM sleep-disordered breathing. AU - Chami, Hassan A.. AU - Baldwin, Carol M.. AU - Silverman, Angela. AU - Zhang, Ying. AU - Rapoport, David. AU - Punjabi, Naresh M.. AU - Gottlieb, Daniel J.. PY - 2010/5/1. Y1 - 2010/5/1. N2 - Rationale: The impact of REM-predominant sleep-disordered breathing (SDB) on sleepiness, quality of life (QOL), and sleep maintenance is uncertain. Objective: To evaluate the association of SDB during REM sleep with daytime sleepiness, health-related QOL, and difficulty maintaining sleep, in comparison to their association with SDB during non-REM sleep in a community-based cohort. Methods: Cross-sectional analysis of 5,649 Sleep Heart Health Study participants (mean age 62.5 [SD = 10.9], 52.6% women, 22.6% ethnic minorities). SDB during REM and non-REM sleep was quantified using polysomnographically derived apnea-hypopnea index in REM (AHIREM) and non-REM (AHINREM) sleep. Sleepiness, ...
i cant sleep at night because of that video vine home remedy sleep aid | maintenance insomnia i cant sleep the night before...i can't sleep at night because of that video vine home remedy sleep aid | maintenance insomnia i can't sleep the night before...
Genes may play a significant role in how much sleep we need. Scientists have identified several genes involved with sleep and sleep disorders, including genes that control the excitability of neurons, and "clock" genes such as Per, tim, and Cry that influence our circadian rhythms and the timing of sleep. Genome-wide association studies have identified sites on various chromosomes that increase our susceptibility to sleep disorders. Also, different genes have been identified with such sleep disorders as familial advanced sleep-phase disorder, narcolepsy, and restless legs syndrome. Some of the genes expressed in the cerebral cortex and other brain areas change their level of expression between sleep and wake. Several genetic models-including the worm, fruit fly, and zebrafish-are helping scientists to identify molecular mechanisms and genetic variants involved in normal sleep and sleep disorders. Additional research will provide better understand of inherited sleep patterns and risks of ...
PDF] Healthy Sleep Habits Download Read EPUB Online | Download PDF for FreePDF] Healthy Sleep Habits Download Read EPUB Online | Download PDF for Free
Becoming a parent is, without question, a major life event. Caring for your new baby is at once exciting, joyful, and exhausting. Now to help with your bundle of joy is this bundle of four indispensable books. The Essential Library for New Moms gathers top experts to answer all your questions, from sleeping to eating to health and wellness. HEALTHY SLEEP HABITS, HAPPY CHILD Marc Weissbluth, M.D. In this perennial favorite, Dr. Marc Weissbluth, one of the countrys leading pediatricians, shares his groundbreaking approach to solving and preventing your childrens sleep problems, from infancy through adolescence. Healthy Sleep Habits, Happy Child is a step-by-step resource for instituting beneficial behaviors within the framework of your childs natural sleep cycles. It includes information on the prevention and treatment of sleep problems, ways to naturally get your baby to fall asleep, help for working moms and children with sleep issues, the benefits and drawbacks of allowing kids to sleep in ...
Stress and dream sleep are linked to pathways of brain cell death and survivalStress and dream sleep are linked to pathways of brain cell death and survival
Monitoring their sleeping patterns, researchers identified an increase in the duration and continuity of REM sleep and specific brain oscillations characteristic of REM sleep, whereas deep sleep, or non-REM sleep, did not change. The changes in REM sleep were very tightly linked to deficiency in the regulation of the stress hormone corticosterone. Mild stress also caused changes in gene expression in the brain. The first and most distinct consequence of daily mild stress is an increase in rapid-eye-movement (REM) sleep, a new study in the journal PNAS reports. The research also demonstrated that this increase is associated with genes involved in cell death and survival. REM sleep, also known as paradoxical sleep, is the sleep state during which we have most of our dreams and is involved in the regulation of emotions and memory consolidation. REM sleep disturbances are common in mood disorders, such as depression. However, little was known about how sleep changes are linked to molecular changes in the
Sleep loss in early childhood may contribute to the development of ADH... ( DARIEN IL Short sleep duration may ...)Sleep loss in early childhood may contribute to the development of ADH... ( DARIEN IL Short sleep duration may ...)
Health, ...DARIEN IL Short sleep duration may contribute to the development or ...Results show that less sleep in preschool-age children significantly p... Children who were reported to sleep less in preschool were rated by t...According to the authors attention-deficit/hyperactivity disorder is ...,Sleep,loss,in,early,childhood,may,contribute,to,the,development,of,ADHD,symptoms,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Tips for Infant and Parent Sleep (TIPS) - Full Text View - ClinicalTrials.govTips for Infant and Parent Sleep (TIPS) - Full Text View - ClinicalTrials.gov
Infant and maternal sleep in the postpartum are related, and influenced by the mothers understanding of infant sleep behavior, the environmental and social cues for sleep presented to the infant, development of the infants sleep physiology, maternal sleep habits and behaviors, and maternal feelings related to her sleep and her babys sleep. These factors may be modifiable through the use of behavioral-educational interventions. A randomized controlled trial design will be used to answer whether a behavioral-educational sleep intervention and support from a nurse in the immediate postpartum improves maternal and infant sleep 6 weeks later. Sleep-wake patterns will be analyzed through the use of actigraphy, a wristwatch-like device that measures sleep-wake activity. This is a pilot study which will test the usefulness and practicality of this type of program, so that a larger scale study can be developed ...
Sleep Apnea :: Sleep Apnea CenterSleep Apnea :: Sleep Apnea Center
There are two ways to conduct a sleep study in order to obtain a diagnosis of sleep disordered breathing. Either a study done at a sleep lab or home sleep testing. A sleep study can be recommended by either a physician or in my case a dentist. Sleep studies are recommended after an interview with a patient that has yielded a high pre-test probability of having some form of sleep disorded breathing. Risk factors to name a few are as follows: Daytime sleepiness, disrupted sleep, habitual snoring, obesity, observed chocking and gasping, high blood pressure, acid reflux during sleep. These listed symptoms are some but not all of the negative health effects of sleep apnea. Outside of serious health conditions home sleep testing is appropriate for most people. If you would like to undergo a sleep study in the privacy of your home give my office a call today and be on your way to quality sleep and a healthier longer life. ...
Healthy Sleep Habits | Go Ask Alice!Healthy Sleep Habits | Go Ask Alice!
Sleep plays an integral role in maintaining physical and mental health. Not getting enough quality sleep can interfere with a persons ability to store newly learned information, potentially leading to a negative impact on academic performance. In addition, sleep deprivation is associated with daytime sleepiness, depressed mood, impaired concentration and memory, and a weakened immune system. Practicing healthy sleep habits (also known as good sleep hygiene) can make a big difference in a persons quality of life. A considerable amount of research has demonstrated that practicing sleep hygiene strategies such as the ones listed below, improves sleep quality and prevents sleep disturbances among university students.. ...
Sleep cycleSleep cycle
Sleep is an essential part of good health, as important as a balanced diet and regular exercise. Unfortunately, most Americans view sleep as a waste of time. We as a society don t place enough value on sleep, says Steve Gardner, director of marketing for the Sleep Wellness Institute and executive director of the Reggie White Sleep Disorders Foundation.. Dr. Rose Franco, associate director of the Sleep Disorders Program at the Medical College of Wisconsin, says people don t make sleep a priority. We need to do a better job of making time to sleep, she says.. A study by the National Sleep Foundation indicates that 60 to 70 percent of the population in the United States doesn t get enough sleep at night. Adults need seven to nine hours of sleep every night, but most people average just six and one-half hours. When you don t get enough sleep, your body develops a sleep debt one of the hardest debts to repay, Gardner says. It keeps accumulating and you feel more and more exhausted.. Although ...
Sleep at Altitude | High Altitude HealthSleep at Altitude | High Altitude Health
Change in Breathing Pattern. Many theories state that the "periodic breathing pattern," common during sleep at high altitude, is a potential cause of sleep disturbances. Periodic breathing is a form of Cheyne-Stokes respiration and reflects changes in neural signaling due to hypoxia and alkalosis during sleep.4 Hypoxia is a respiratory stimulant while alkalosis is a respiratory depressant.4 This mixed signaling is the source of the altered breathing during non-REM sleep encountered at altitudes over 2500 m. The frequency of periodic breathing during sleep increases as the altitude increases.3,4,7. Decreased Sleep Efficiency Compared with sea level, several studies have depicted that sleep at higher altitude is characterized by decreased sleep efficiency, prolonged superficial stages of sleep, and reduced stages of deep sleep.12 The image below is a qualitative representation of sleep structure recorded at sea level and at high altitude. The area encircled by the outer line reflects the time in ...
natural sleep aid starts with a i cant sleep at night so i sleep all day | i cant sleep early at night i cant sleep at...natural sleep aid starts with a i can't sleep at night so i sleep all day | i can't sleep early at night i can't sleep at...
This third one is what I study. The "synaptic homeostasis hypothesis" is this idea that during the day, we make all these connections with the world around us. It used to be like, "Dont go over there-the lions live there now." Now its like, "What did Barbara say to me in the office?" These excitatory connections we make during the day result in the neurons in our brains getting overall higher activation. Then during the nighttime when we sleep, we have a downregulating process where the things that didnt really matter to your survival sink to the bottom, and the things that are most relevant to your survival rise to the top. What deep sleep does is all the neural processing, and what REM sleep [rapid-eye-movement sleep] and light sleep do is basically integrate that into your long-term personality and understanding of the world. ...
How sleep can balance your hormones | Maggie Chilton BA (Hons), RHNHow sleep can balance your hormones | Maggie Chilton BA (Hons), RHN
How sleep can balance your hormones.. Are you getting enough? Think you can "survive" on 5-6 hours? There is strong evidence to say that anything less than 7 hours will have a dramatic impact on your immune system and affect your amygdala (a section of the brain that is responsible for detecting fear and preparing for emergency events) which in turn will affect your cortisol levels, making you age more rapidly and making you gain weight and throw other hormones out of whack - and these are just some of the examples!. On a basic level we sleep in 90 minute cycles which run from REM (rapid eye movement) to light sleep to deep sleep, with deep sleep generally coming at the end of the cycle.. During our light sleep we fall into a slow mantra*, a rhymic flow of data processing and compartmentalizing. This stage is particularly important for those with high blood pressure.. The part of sleep that eluded me the most over the past year was deep sleep. I was falling well below the amount I needed to get ...
Quit Drinking Alcohol and Youll Sleep BetterQuit Drinking Alcohol and You'll Sleep Better
There is no question that a cocktail or a glass of wine is relaxing at the end of a long day. You might even think that drinking alcohol helps you sleep.. While it is true that alcohol has a sedative effect which promotes sleep. What you might not know is that if you drink alcohol to help you sleep, you will not only get less sleep, but the quality of your sleep is significantly diminished.. Alcohol Interrupts Normal Sleep Rhythms. In a report released in 2004 by Science Daily.com, medical researchers at Wake Forest University Baptist Medical Center in San Diego, California studied the relationship between alcohol consumption and sleep in order to find out why alcoholics who have quit drinking return to alcohol to help them sleep.. Researchers saw that while the sedative effects of alcohol promote sleep, in the second half of sleep cycles, the brain waves involved in normal sleep rhythms are disrupted, resulting in poor sleep quality . Furthermore, the brain eventually builds up a tolerance to ...
Effect of sleep/wake state on arterial blood pressure in genetically identical mice<...Effect of sleep/wake state on arterial blood pressure in genetically identical mice<...
TY - JOUR. T1 - Effect of sleep/wake state on arterial blood pressure in genetically identical mice. AU - Schaub, C. D.. AU - Tankersley, C.. AU - Schwartz, A. R.. AU - Smith, P. L.. AU - Robotham, J. L.. AU - ODonnell, C. P.. PY - 1998/7. Y1 - 1998/7. N2 - Genetic determinants may contribute to the large variability in arterial blood pressure responses to changes in sleep/wake state in humans. In this study, we developed techniques to examine the relationship between sleep/wake state and mean arterial pressure (MAP) in unrestrained, genetically identical mice (C57BL/6J; n = 9). The left common carotid artery was catheterized, and arterial blood gases were analyzed 24-48 h postsurgery to verify normal respiratory and metabolic function. The animals were then allowed to cycle naturally through sleep/wake states over a 3- to 4-h period while continuous polysomnography and arterial pressure measurements were made. The MAP decreased from quiet wakefulness to non-rapid-eye-movement sleep (9.8 ± 1.3 ...
Outcomes of Infant Sleep Problems: A Longitudinal Study of Sleep, Behavior, and Maternal Well-Being | ELECTRONIC ARTICLES |...Outcomes of Infant Sleep Problems: A Longitudinal Study of Sleep, Behavior, and Maternal Well-Being | ELECTRONIC ARTICLES |...
This is the first study to examine the long-term outcomes of sleep problems in a community sample of infants, together with the long-term impact of a behavioral sleep intervention on infant sleep problems. Sleep problems were identified in approximately one third of the 3- to 4-year-old children surveyed, all of whom had had significant sleep problems as infants. These children at 3 to 4 years were more likely to need an adult to nurse them to sleep. They also had higher Internalizing and Externalizing Scores and Aggressive Behavior and Somatic Problems subscale scores of the CBCL than children without sleep problems. Their mothers had higher EPDS scores as well as difficulties with their partner undermining the management of their child. Despite this, the children and their families were generally functioning well, and 69% of mothers reported that their childs sleep problem had resolved from infancy. The resolution of sleep problems in children who had received an infant sleep intervention was ...
Faculty Profile: Paul A. Rosenberg, MD, PhD | Division of Sleep Medicine @ Harvard Medical SchoolFaculty Profile: Paul A. Rosenberg, MD, PhD | Division of Sleep Medicine @ Harvard Medical School
In collaboration with Dr. Tarja Porkka-Heiskanen, we tested the role of nitric oxide (NO) in sleep homeostasis by using in vivo microdialysis to administer compounds into the rat basal forebrain that increase or decrease concentrations of NO. Consistent with our hypothesis, we found that nitric oxide production is required for the production of NREM recovery sleep following sleep deprivation. However, using specific inhibitors of nitric oxide synthases, we found that iNOS rather than nNOS produced the nitric oxide involved in homeostatic sleep regulation. The generation of NREM recovery sleep was tightly associated with increases in adenosine levels in the BF: when adenosine concentration was not elevated, recovery sleep was not induced while all cases of recovery sleep induction were preceded by adenosine increases. These results suggest that the elevation of NO in the BF during prolonged wakefulness is a specific mechanism for producing NREM recovery sleep. We are now interested in the ...
CDC - How Much Sleep Do I Need? - Sleep and Sleep DisordersCDC - How Much Sleep Do I Need? - Sleep and Sleep Disorders
Although the amount of sleep you get each day is important, other aspects of your sleep also contribute to your health and well-being. Good sleep quality is also essential. Signs of poor sleep quality include not feeling rested even after getting enough sleep, repeatedly waking up during the night, and experiencing symptoms of sleep disorders (such as snoring or gasping for air). Improving sleep quality may be helped by better sleep habits or being diagnosed and treated for any sleep disorder you may have.. ...
Silent Sleep Training Is Ready To Revolutionize Sleep Apnea Treatment | Daily HeraldSilent Sleep Training Is Ready To Revolutionize Sleep Apnea Treatment | Daily Herald
Get rid of your sleep apnea with only 15 minutes of daily fun training. With Silent Sleep Training®, you can train away obstructive sleep apnea and snoring and soon sleep without sleep equipment.. SWITZERLAND, October 23, 2020 /EINPresswire.com/ -- "Silent Sleep Training®" is now available in Europe and the U.S.A. with further countries to follow early 2021. The proven therapeutic approach alleviates and demonstrably eliminates obstructive sleep apnea and snoring by strengthening the throat muscles, as scientific studies at the University Hospital of Zurich have shown. Silent Sleep Training consists of a "Medical Didgeridoo®" and an app. This revolutionary therapeutic approach is being launched with an Indiegogo campaign at an introductory price. Sleep apnea is a dangerous and restrictive condition. Currently it is estimated that close to a billion people worldwide suffer from sleep apnea. Until now, many have had to put up with conventional sleep aids and sleep equipment - all without any ...
Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index - Burwood ChiropracticShort Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index - Burwood Chiropractic
Study participants were 1,024 volunteers from the Wisconsin Sleep Cohort Study, a population-based longitudinal study of sleep disorders. Participants underwent nocturnal polysomnography and reported on their sleep habits through questionnaires and sleep diaries. Following polysomnography, morning, fasted blood samples were evaluated for serum leptin and ghrelin (two key opposing hormones in appetite regulation), adiponectin, insulin, glucose, and lipid profile. Relationships among these measures, BMI, and sleep duration (habitual and immediately prior to blood sampling) were examined using multiple variable regressions with control for confounding factors.. A U-shaped curvilinear association between sleep duration and BMI was observed. In persons sleeping less than 8 h (74.4% of the sample), increased BMI was proportional to decreased sleep. Short sleep was associated with low leptin (p for slope = 0.01), with a predicted 15.5% lower leptin for habitual sleep of 5 h versus 8 h, and high ghrelin ...
Sleep Duration, Sleep Quality, and Markers of Subclinical Arterial Disease in Healthy Men and WomenSleep Duration, Sleep Quality, and Markers of Subclinical Arterial Disease in Healthy Men and Women
OBJECTIVE: Short and long sleep duration are associated with increased risk of clinical cardiovascular events, but the association between sleep duration and subclinical cardiovascular disease is not well established. We examined the association between sleep duration and sleep quality with coronary artery calcification (CAC) and with brachial-ankle pulse wave velocity (PWV) in a large sample of young and middle-aged asymptomatic adults. APPROACH AND RESULTS: We conducted a cross-sectional study of adult men and women who underwent a health checkup examination, including assessment of sleep duration and quality and coupled with either CAC (n=29 203) or brachial-ankle PWV (n=18 106). The multivariate-adjusted CAC score ratios (95% confidence interval) comparing sleep durations of /=9 hours with 7 hours of sleep were 1.50 (1.17- 1.93), 1.34 (1.10-1.63), 1.37 (0.99-1.89), and 1.72 (0.90-3.28), respectively (P for quadratic trend=0.002). The corresponding average differences in ...
Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila - CSHL...Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila - CSHL...
Our understanding of the molecular mechanisms underlying sleep homeostasis is limited. We have taken a systematic approach to study neural signaling by the transmitter 5-hydroxytryptamine (5-HT) in drosophila. We have generated knockout and knockin lines for Trh, the 5-HT synthesizing enzyme and all five 5-HT receptors, making it possible for us to determine their expression patterns and to investigate their functional roles. Loss of the Trh, 5HT1a or 5HT2b gene decreased sleep time whereas loss of the Trh or 5HT2b gene diminished sleep rebound after sleep deprivation. 5HT2b expression in a small subset of, probably a single pair of, neurons in the dorsal fan-shaped body (dFB) is functionally essential: elimination of the 5HT2b gene from these neurons led to loss of sleep homeostasis. Genetic ablation of 5HT2b neurons in the dFB decreased sleep and impaired sleep homeostasis. Our results have shown that serotonergic signaling in specific neurons is required for the regulation of sleep ...
Frontiers | Neuroendocrine and Peptidergic Regulation of Stress-Induced REM Sleep Rebound | EndocrinologyFrontiers | Neuroendocrine and Peptidergic Regulation of Stress-Induced REM Sleep Rebound | Endocrinology
Sleep homeostasis depends on the length and quality (occurrence of stressful events, for instance) of the preceding waking time. Forced wakefulness (sleep deprivation or sleep restriction) is one of the main tools used for the understanding of mechanisms that play a role in homeostatic processes involved in sleep regulation and their interrelations. Interestingly, forced wakefulness for periods longer than 24 h activates stress response systems, whereas stressful events impact on sleep pattern. Hypothalamic peptides (CRH, prolactin and the CLIP/ACTH18-39) play an important role in the expression of stress-induced sleep effects, essentially by modulating REM sleep, which has been claimed to affect the organism resilience to the deleterious effects of stress. Some of the mechanisms involved in the generation and regulation of sleep and the main peptides/hypothalamic hormones involved in these responses will be discussed in this review.
Clinical Services - Sleep NeurologyClinical Services - Sleep Neurology
Sleep Medicine is a relatively new field of medicine spanning multiple disciplines. The range of healthcare professionals involved in the management of sleep disorders includes Neurologists, Respiratory physicians, Psychiatrists, Psychologists, ENT surgeons, Sleep Technologists and Respiratory Therapists.. Sleep disorders are conditions occurring around and during sleep which disturb normal sleep. Sleep is an important time for rest and restoration of the mind and body. When sleep is disrupted, our health is impaired. Sleep disorders affect the brain and physical functioning, and often worsen existing conditions such as diabetes, high blood pressure, heart disease, stroke and depression. People who do not get enough sleep are also at risk of more frequent accidents, and poorer performance at school or work.. People at risk for sleep problems include those with irregular work and sleep schedules, poorly managed stress, depression and anxiety, chronic pain, and diseases of the brain such as ...
Sleep MedicineSleep Medicine
The Sleep Center at Westchester Medical Center is a full-service, state-of-the-art laboratory equipped to treat a wide range of sleep disorders in both adults and children.. Nearly 1 in 10 people will experience a sleep disorder, with the majority going undiagnosed and untreated. Advances in sleep medicine and technology have made it possible to restore the good nights sleep that is fundamental to health and well-being. The Sleep Center at Westchester Medical Center is a full service, state-of-the-art laboratory equipped to treat a wide range of sleep disorders in both adults and children.. The Sleep Centers experienced team of adult and pediatric physicians and sleep specialists employ state-of-the-art technology to diagnose and manage a wide variety of sleep disorders. As part of a major academic medical center, the Sleep Center works in concert with on-site specialists in such adult and pediatric disciplines as neurology, sleep medicine, cardiology, otolaryngology, pulmonology and oral and ...
Different Types Of Sleep Apnea Treatments - Hume Health & LifestyleDifferent Types Of Sleep Apnea Treatments - Hume Health & Lifestyle
Sleep is an important factor in our health. Without the right amount of sleep, the body mechanisms fail to perform their functions due to fewer reactions of hormones leading to poorer health conditions as well as frequent illnesses. A maximum amount of 7 hours of sleep is needed four bodies to complete the 24-hour cycle.. An individual can go through stages of sleep such as mild sleep to deep sleep states, but in between the sleep cycles, there are sleep disorders than an individual might experience, yet be completely unaware of it. One of the most common talked sleep disorder that young adults and older persons face is the sleep Apnea sleep disorder than is followed with many other side effects in sleep duration as well as day to day life.. ...
Sleep disturbance in post-traumatic stress disorder (PTSD): a systematic review and meta-analysis of actigraphy studiesSleep disturbance in post-traumatic stress disorder (PTSD): a systematic review and meta-analysis of actigraphy studies
European Journal of Psychotraumatology. Catrin Lewis, Katie Lewis, Neil Kitchiner, Samantha Isaac , Ian Jones & Jonathan I. Bisson. https://doi.org/10.1080/20008198.2020.1767349. Abstract. Background: Sleep disturbance has been described as a hallmark symptom of posttraumatic stress disorder (PTSD). Although there are robust findings of self-reported sleep disturbance in PTSD, evidence of sleep disturbance measured using actigraphy is less certain.. Objective: To conduct a systematic review and meta-analysis to determine whether there are any significant differences between individuals with and without PTSD in actigraph-derived sleep measures.. Method: Case-control studies comparing participants with current PTSD to those without PTSD were eligible for inclusion. Sleep parameters of interest were: (1) total sleep time; (2) sleep onset latency; (3) wake after sleep onset (WASO); and (4) sleep efficiency. Data were meta-analysed as standardised mean differences (SMDs) and potential sources of ...
Heart rate variability during waking and sleep in healthy males and females | Read by QxMDHeart rate variability during waking and sleep in healthy males and females | Read by QxMD
STUDY OBJECTIVES: The study goal was to investigate autonomic activity with heart rate variability analysis during different sleep stages in males and females.. DESIGN: The study utilized a 2 Groups (males, females) x 4 States (waking, stage 2 sleep, stage 4 sleep, rapid-eye movement sleep) mixed design with one repeated, within-subjects factor (i.e., state).. SETTING: The study was carried out in the sleep laboratory of the Thomas N. Lynn Institute for Healthcare Research.. PARTICIPANTS: Twenty-four healthy adults (fourteen females and ten males).. INTERVENTIONS: NA.. MEASUREMENTS AND RESULTS: All participants underwent polysomnographic monitoring and electrocardiogram recordings during pre-sleep waking and one night of sleep. Fifteen-minute segments of beat-to-beat heart rate intervals during waking, stage 2 sleep, stage 4 sleep, and REM sleep were subjected to spectral analysis. Compared to NREM sleep, REM sleep was associated with decreased high frequency (HF) band power, and significantly ...
Study: Maternal Sleep Positions may Influence Pregnancy OutcomesStudy: Maternal Sleep Positions may Influence Pregnancy Outcomes
Pregnant women in Ghana who slept on their back (supine sleep) were at an increased risk of stillbirth compared to women who did not sleep on their back, according to new research led by a University of Michigan researcher.. "Association of maternal sleep practices with pre-eclampsia, low birth weight, and stillbirth among Ghanaian women" is published in the International Journal of Gynecology and Obstetrics.. Read Abstract.. In the study, researchers found that supine sleep increased the risk of low birth weight by a factor of 5 and that it was the low birth weight that explained the high risk for stillbirth in these women.. The studys senior author, Louise OBrien, Ph.D., M.S., associate professor in U-Ms Sleep Disorders Center, says that although this study was conducted in a maternity hospital in Ghana - a country that has high perinatal mortality - a recent case-control study from New Zealand also found a link between maternal supine sleep and stillbirth.. Stillbirth is a traumatic event ...
Better sleep Archives - In Good Health CoachBetter sleep Archives - In Good Health Coach
For a good nights sleep try these healthy sleep habits, by optimizing your sleep sanctuary. To improve your sleep, you may need to modify some of your lifestyle choices, including diet and exercise. When your circadian rhythms are disrupted your body produces less melatonin (a hormone and an anti-oxidant) and has less ability to fight disease, since melatonin helps suppress free radicals.. Impaired sleep an also increase stress-related disorder, including: Heart Disease, Stomach Ulcers, Constipation, Mood Disorders. One study has even shown that people with chronic insomnia have a three times greater risk of dying from any cause. Lost sleep is lost forever, and persistent lack of sleep has a cumulative effect when it comes to disrupting your health. Whether you have trouble falling asleep, waking up too often, or feeling inadequately rested when you wake up in the morning-or maybe you simply want to improve the quality of your sleep-Try these healthy sleep habits:. 1. Sleep in complete ...
ways to get better sleep - ways to get better sleep online Wholesalersways to get better sleep - ways to get better sleep online Wholesalers
ways to get better sleep & ways to get better sleep online Wholesalers - choose ways to get better sleep from 4213 list of China ways to get better sleep Manufacturers.
J Clin Psychiatry/Sleep Changes After 4 Consecutive Days of Venlafaxine Administration in Normal VolunteersJ Clin Psychiatry/Sleep Changes After 4 Consecutive Days of Venlafaxine Administration in Normal Volunteers
Background: The purpose was to examine the effect of the antidepressant drug venlafaxine on sleep architecture and periodic leg movements of sleep (PLMS) in normal volunteers.. Method: Eight normal volunteers were studied under laboratory sleep conditions as follows: 1 acclimatization night, 1 baseline night, and 4 consecutive nights of venlafaxine p.o. administration (75 mg during the first 2 nights and 150 mg the last 2 nights). Results: Venlafaxine increased both wake time and sleep stage I. Sleep stages II and III were reduced. REM sleep time was reduced after the first venlafaxine dose, and, by the fourth night, REM sleep was completely suppressed in all volunteers. Six of the eight volunteers showed PLMS at a frequency above 25 per hour. Conclusion: Venlafaxine produces several sleep disturbances, which include abnormal leg movements. ...
Sleep, Pain, and Breathing : Anesthesia & AnalgesiaSleep, Pain, and Breathing : Anesthesia & Analgesia
Sleep and pain have a difficult, multidimensional relationship. Pain disturbs sleep.1-4 Disturbed sleep aggravates pain.5-8 Treatment of sleep disorders can reduce pain.9 Relieving pain can improve sleep although, as shown by Correa and colleagues10 in this issue of Anesthesia & Analgesia, where opioids are involved this is not uniformly the case.. Sleep is a vulnerable state for breathing. Ventilatory drive is reduced because of loss of the stimulatory effects of wakefulness, accompanied by reduction in hypercapnic and hypoxic responsiveness. Sleep depresses muscle activation, reflex gain, and arousal responses. These changes are more prominent in rapid eye movement than non-rapid eye movement sleep. Upper airway obstruction and/or hypoventilation occur in predisposed subjects.11 This makes sleep of enormous relevance to anesthesiologists, as these state-related physiological changes are also present during anesthesia. Knowledge of breathing behavior during sleep is helpful in predicting likely ...
Serval - Age-related changes in sleep in inbred mice are genotype dependent.Serval - Age-related changes in sleep in inbred mice are genotype dependent.
Aging produces major changes in sleep structure and intensity which might be linked to cognitive impairment in the elderly. In this study, the genetic contribution to age-related changes in sleep was assessed in three inbred mouse strains of various ages. Baseline sleep and the response to 6 hours sleep deprivation (SD) achieved by gentle handling were quantified in young, middle-aged, and older male mice using electroencephalography. Total sleep time initially increased with age but then decreased in the oldest group mainly due to changes in sleep duration during the active phase. The effect of age on electroencephalographic (EEG) delta power depends on genotype and sleep pressure level with SD increasing the age-related differences. The strong effect of age upon the spectral profile of the different behavioral states was modulated by genetic background. Overall, our results suggest that sleep pressure can modulate the effect of age, that most sleep variables do not monotonically chan
Sleep Apnea | RemSleepSleep Apnea | RemSleep
Chronic snoring is a strong indicator of sleep apnea and should be evaluated by a health professional. Since people with sleep apnea tend to be sleep deprived, they may suffer from sleeplessness and a wide range of other symptoms such as difficulty concentrating, depression, irritability, sexual dysfunction, learning and memory difficulties, and falling asleep while at work, on the phone, or driving. Left untreated, symptoms of sleep apnea can include disturbed sleep, excessive sleepiness during the day, high blood pressure, heart attack, congestive heart failure, cardiac arrhythmia, stroke or depression.. ​One of the most common methods used to diagnose sleep apnea is a sleep study, which may require an overnight stay at a sleep center. The sleep study monitors a variety of functions during sleep including sleep state, eye movement, muscle activity, heart rate, respiratory effort, airflow, and blood oxygen levels. ...
Factor analysis of the pittsburgh sleep quality index in breast cancer survivors<...Factor analysis of the pittsburgh sleep quality index in breast cancer survivors<...
TY - JOUR. T1 - Factor analysis of the pittsburgh sleep quality index in breast cancer survivors. AU - Otte, Julie L.. AU - Rand, Kevin L.. AU - Carpenter, Janet S.. AU - Russell, Kathleen M.. AU - Champion, Victoria L.. PY - 2013/3/1. Y1 - 2013/3/1. N2 - Context: Sleep is a significant problem in breast cancer survivors (BCS) and measured frequently using the Pittsburgh Sleep Quality Index (PSQI). Thus, it is important to evaluate its factor structure. The two-process model of sleep regulation was the theoretical framework for this study. Objectives: To perform a confirmatory factor analysis of the PSQI in BCS and compare results between African-American and Caucasian BCS. Methods: This was a secondary analysis of cross-sectional data using local and regional health care facilities and Eastern Cooperative Oncology Group referrals. The study included 1174 nondepressed BCS (90% Caucasian), with a mean age of 57 years and median PSQI global scores at the cutoff for poor sleep (median = 6.00, ...
Effects of insomnia symptoms and objective short sleep duration on memory performance in youths. - Nuffield Department of...Effects of insomnia symptoms and objective short sleep duration on memory performance in youths. - Nuffield Department of...
Sleep quantity and quality are both important for optimal development and functioning during youth. Yet few studies have examined the effects of insomnia symptoms and objective short sleep duration on memory performance among adolescents and young adults. One-hundred and ninety participants (female: 61.6%) aged from 12 to 24 years completed this study. All participants underwent a clinical interview, a 7-day actigraphic assessment, a battery of self-report questionnaires and cognitive tests to assess working memory and episodic memory. Insomnia symptoms were defined as a score ≥ 9 on the Insomnia Severity Index, and objective short sleep duration was defined as average total sleep time less than 7 hr for those aged 12-17 years, and 6 hr for those aged 18 years and above as assessed by actigraphy. Insomnia symptoms were significantly associated with worse self-perceived memory (p | .05) and poorer performance on the digit span task (p | .01), but not the dual N-back task and verbal learning task. There
Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: empirical data and simulations. - Semantic ScholarEffects of sleep deprivation on sleep and sleep EEG in three mouse strains: empirical data and simulations. - Semantic Scholar
Gene targeted mice can be used as models to investigate the mechanisms underlying sleep regulation. Three commonly used background strains for gene targeting (129/Ola, 129/SvJ and C57BL/6J) were subjected to 4-h and 6-h sleep deprivation (SD), and their sleep and sleep EEG were continuously recorded. The two-process model of sleep regulation has predicted the time course of slow-wave activity (SWA) in nonREM sleep after several sleep-wake manipulations in humans and the rat [3] [9]. We tested the capacity of the model to predict SWA in nonREM sleep on the basis of the temporal organization of sleep in mice. The strains differed in the amount and distribution of sleep and the time course of SWA. After spontaneous waking episodes of 10-30 min as well as after SD, SWA was invariably increased. Simulations of the time course of SWA were successful for 129/SvJ and C57BL/6J, but were not satisfactory for 129/Ola. Since the time constants are assumed to reflect the dynamics of the physiological processes
The cognitive cost of sleep lost. | Department of AnesthesiologyThe cognitive cost of sleep lost. | Department of Anesthesiology
A substantial body of literature supports the intuitive notion that a good nights sleep can facilitate human cognitive performance the next day. Deficits in attention, learning & memory, emotional reactivity, and higher-order cognitive processes, such as executive function and decision making, have all been documented following sleep disruption in humans. Thus, whilst numerous clinical and experimental studies link human sleep disturbance to cognitive deficits, attempts to develop valid and reliable rodent models of these phenomena are fewer, and relatively more recent. This review focuses primarily on the cognitive impairments produced by sleep disruption in rodent models of several human patterns of sleep loss/sleep disturbance. Though not an exclusive list, this review will focus on four specific types of sleep disturbance: total sleep deprivation, experimental sleep fragmentation, selective REM sleep deprivation, and chronic sleep restriction. The use of rodent models can provide greater ...
Sleep Apnea ScreeningSleep Apnea Screening
... This month CNN.com had an article that was on screening for sleep apnea. The article discusses how sleep apnea cant usually be detected by doctors during routine office visits but screening from your dentist may help. Recent studies have shown that teeth grinding is a major indicator for obstructive sleep apnea. Dentists can screen for teeth grinding. The article clarifies that a dentist can tell you definitively if you grind your teeth or not but they do not diagnose sleep apnea. Medical specialists are the only medical providers who can officially diagnose and treat sleep apnea. The article highlights that sufferers of sleep apnea may never get the benefits of the deep sleep. Symptoms of untreated sleep apnea include feeling sleepy or tired during waking hours, grinding teeth and snoring. Sleep apnea is a condition that affects an estimated one in fifteen Americans, but often goes unnoticed. Sleep apnea can range from mild to severe. The most common sleep apnea is ...
Rapid eye movement sleep promotes cortical plasticity in the developing brain - Surrey Research Insight Open AccessRapid eye movement sleep promotes cortical plasticity in the developing brain - Surrey Research Insight Open Access
Rapid eye movement sleep is maximal during early life, but its function in the developing brain is unknown. We investigated the role of rapid eye movement sleep in a canonical model of developmental plasticity in vivo (ocular dominance plasticity in the cat) induced by monocular deprivation. Preventing rapid eye movement sleep after monocular deprivation reduced ocular dominance plasticity and inhibited activation of a kinase critical for this plasticity (extracellular signal-regulated kinase). Chronic single-neuron recording in freely behaving cats further revealed that cortical activity during rapid eye movement sleep resembled activity present during monocular deprivation. This corresponded to times of maximal extracellular signal-regulated kinase activation. These findings indicate that rapid eye movement sleep promotes molecular and network adaptations that consolidate waking experience in the developing brain.. ...
Rapid eye movement sleep promotes cortical plasticity in the developing brain | Science AdvancesRapid eye movement sleep promotes cortical plasticity in the developing brain | Science Advances
Rapid eye movement sleep is maximal during early life, but its function in the developing brain is unknown. We investigated the role of rapid eye movement sleep in a canonical model of developmental plasticity in vivo (ocular dominance plasticity in the cat) induced by monocular deprivation. Preventing rapid eye movement sleep after monocular deprivation reduced ocular dominance plasticity and inhibited activation of a kinase critical for this plasticity (extracellular signal-regulated kinase). Chronic single-neuron recording in freely behaving cats further revealed that cortical activity during rapid eye movement sleep resembled activity present during monocular deprivation. This corresponded to times of maximal extracellular signal-regulated kinase activation. These findings indicate that rapid eye movement sleep promotes molecular and network adaptations that consolidate waking experience in the developing brain. ...
childhood sleep disorders - antone4755s blogchildhood sleep disorders - antone4755's blog
obstructive sleep apnea vs central sleep apnea obstructive sleep apnea syndrome video sleep disorder center detroit mi childhood sleep disorders apnea monitor childhood sleep disorders sleep apnea symptoms sleep apnea treatment europe snore aids childhood sleep disorders Many childhood sleep problems are related to poor sleep habits or to anxiety...
Self-reported sleep disturbances in renal transplant recipients - Zurich Open Repository and ArchiveSelf-reported sleep disturbances in renal transplant recipients - Zurich Open Repository and Archive
BACKGROUND: Poor sleep quality (SQ) and daytime sleepiness (DS) are common in renal transplant (RTx) recipients; however, related data are rare. This study describes the prevalence and frequency of self-reported sleep disturbances in RTx recipients. METHODS: This cross-sectional study included 249 RTx recipients transplanted at three Swiss transplant centers. All had reported poor SQ and / or DS in a previous study. With the Survey of Sleep (SOS) self-report questionnaire, we screened for sleep and health habits, sleep history, main sleep problems and sleep-related disturbances. To determine a basis for preliminary sleep diagnoses according to the International Classification of Sleep Disorders (ICSD), 164 subjects were interviewed (48 in person, 116 via telephone and 85 refused). Descriptive statistics were used to analyze the data and to determine the frequencies and prevalences of specific sleep disorders. RESULTS: The sample had a mean age of 59.1 ± 11.6 years (60.2% male); mean time since ...
Yoga for Insomnia - Sleep Disorder, Deep Relaxation, Anxiety & Stress Relief | The World Of Yoga - Sleep Aid Research...Yoga for Insomnia - Sleep Disorder, Deep Relaxation, Anxiety & Stress Relief | The World Of Yoga - Sleep Aid Research...
In the United States as many as forty million people suffer from chronic long term sleep disorders while as many as twenty million have occasional sleep disorders. Good health requires sleep, even though this phenomenon is not completely understood by scientists and medical professionals yet. Sleeps disorders have three major types and one of them is insomnia sleep disorder.. Insomnia is a very common sleep problem that is experienced by millions on occasion and it means a person is not able to fall asleep. A person with insomnia will have a disruption of normal daily life and they will often feel tired most of the time and end up worrying about their lack of sleep. Insomnia sleep disorder can be caused by a number of factors including excessive intake of caffeine or alcohol, emotional difficulties, stress and other underlying diseases. Lack of sleep isnt a disorder in itself, but it is an indication of inadequate sleep and can harm the immune system.. There are three categories of insomnia ...
DMOZ - Health: Conditions and Diseases: Sleep DisordersDMOZ - Health: Conditions and Diseases: Sleep Disorders
Sleep research and sleep medicine have grown rapidly over the last thirty years, partly as a result of the discovery that REM (rapid eye movement) sleep coincided with dreaming and partly because of the discovery of sleep apnea (breathing stopping during sleep). Countries vary in how they deal with sleep disorders; in the U.S. sleep medicine is recognised as a field and it is looked after by the National Heart, Lung and Blood Institute; other medical specialities e.g. neurology, pulmonology, psychiatry, may be influential in other countries. The sleep disorders category is broadly divided into sub-categories that deal with the specific sleep disorders as well as the institutions that regulate, diagnose and treat these disorders. Sleep is affected by the brains biological clock and so is included in this category. Shift-work sleep disorder and jet-lag are well-known problems that reflect the activity of the biological clock. This category consists of some of the major omnibus sites (SleepNet,
Mercy Healths Inspire Therapy treats Obstructive Sleep ApneaMercy Health's 'Inspire Therapy' treats Obstructive Sleep Apnea
Over 22 million Americans suffer from sleep apnea. The causes and intensity of symptoms of sleep apnea vary person to person, so its important to be aware of the treatment options available. Fortunately, Mercy Health has a new treatment for those who suffer from Obstructive Sleep Apnea called the Inspire Therapy.. Medical Director of Sleep Medicine Dr. Christopher Morgan stopped by to explain what sleep apnea is, what symptoms to look out for, and the technology behind new treatment options.. Obstructive sleep apnea is a potentially serious sleep disorder, causing breathing to repeatedly stop and start during sleep. Symptoms include excessive daytime sleepiness, snoring, stopping breathing during sleep, insomnia, excessive nighttime urination, awakening with a dry mouth or sore throat, morning headache, high blood pressure and nighttime sweating.. Patients should treat their sleep apnea so they dont experience daytime fatigue and sleepiness, which can increase the risk for car accidents and ...
Can t sleep wake up breathless - I sleep for 30 60 minutes then wake up coughing for a few minutes what causes this :: Xmms...Can t sleep wake up breathless - I sleep for 30 60 minutes then wake up coughing for a few minutes what causes this :: Xmms...
Waking up at night and feeling like you were unable to breathe properly is the symptom of sleep apnea. A person having sleep apnea is hardly aware of his problem, even during awakening. A person may be having symptoms present for years. Symptoms may be chronic and loud snoring, choking during sleep, and long pauses in breathing. Less common symptoms of sleep apnea are: headaches in the morning, dry mouth, restless. Further sleep apnea is divided in to two types, obstructive and central sleep apnea: In obstructive sleep apnea airway of throat can obstruct breathing during sleep. Central sleep apnea is less common type of sleep apnea ...
Medical Sleep Apnea Devices Market forecasts (2017-2022) with industry chain structure, competitive landscape, new projects and...Medical Sleep Apnea Devices Market forecasts (2017-2022) with industry chain structure, competitive landscape, new projects and...
And Many Others……. Get a PDF Sample of Medical Sleep Apnea Devices Market Research Report. After the basic information, the Medical Sleep Apnea Devices Market report sheds light on the production. Production plants, their capacities, global production and revenue are studied. Also, the Medical Sleep Apnea Devices Market growth in various regions and R&D status are also covered.. Following are Major Table of Content of Medical Sleep Apnea Devices Industry:. • Medical Sleep Apnea Devices Market Competition by Manufacturers. • Medical Sleep Apnea Devices Production, Revenue (Value) by Region (2017-2022). • Medical Sleep Apnea Devices Supply (Production), Consumption, Export, Import by Regions (2017-2022). • Medical Sleep Apnea Devices Production, Revenue (Value), Price Trend by Type. • Medical Sleep Apnea Devices Market Analysis by Application. • Medical Sleep Apnea Devices Manufacturers Profiles/Analysis. • Medical Sleep Apnea Devices Manufacturing Cost Analysis. • Industrial ...
JCSM - Periodic Leg Movements Are Associated with Reduced Sleep Quality in Older Men: The MrOS Sleep StudyJCSM - Periodic Leg Movements Are Associated with Reduced Sleep Quality in Older Men: The MrOS Sleep Study
The results of this study in 2,872 subjects demonstrate that periodic limb movements in sleep are common in elderly men. Overall, we found a strikingly high prevalence of PLMS when using a PLMI threshold of 5 (71%) or 15 (60%). When using a PLMA threshold of 5 (27%) or 15 (6%) as a disease-defining metric, PLMS was common but less prevalent. Importantly, both metrics were associated with poorer sleep outcomes after multivariate adjustment for various possible confounders. A higher PLMA was consistently associated with more frequent arousals, lower sleep efficiency, and a pattern of altered sleep stages suggesting lighter sleep (more stage 1 and 2 and less stage 3-4 and REM). Except for stage 1, REM and sleep efficiency, similar findings were consistently observed for PLMI. These results suggest that leg movements that do not cause arousals as well as those that do cause arousals are associated with perturbed sleep quality, although on average, these associations are modest in this sample with ...
Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in ratsEffects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats
Sleep loss is both common and critically relevant to our society and might lead to the abuse of psychostimulants such as amphetamines, cocaine and modafinil. Since psychoactive substance abuse often occurs within a scenario of sleep deficit, the purpose of this investigation was to compare the sleep patterns of rats challenged with cocaine (7 mg/kg, ip), methamphetamine (7 mg/kg, ip), or modafinil (100 mg/kg, ip) subsequent to paradoxical sleep deprivation (PSD) for 96 h. Our results show that, immediately after 96 h of PSD, rats (10 per group) that were injected with a psychostimulant presented lower percentages of paradoxical sleep compared to those injected with saline (P , 0.01). Regarding slow wave sleep (SWS), rats injected with psychostimulants after PSD presented a late rebound (on the second night subsequent to the injection) in the percentage of this phase of sleep when compared to PSD rats injected with saline (P , 0.05). In addition, the current study has produced evidence of the ...
Acute Sleep Deprivation Enhances the Brains Response to Hedonic Food Stimuli : An fMRI StudyAcute Sleep Deprivation Enhances the Brain's Response to Hedonic Food Stimuli : An fMRI Study
Context:. There is growing recognition that a large number of individuals living in Western society are chronically sleep deprived. Sleep deprivation is associated with an increase in food consumption and appetite. However, the brain regions that are most susceptible to sleep deprivation-induced changes when processing food stimuli are unknown.. Objective:. Our objective was to examine brain activation after sleep and sleep deprivation in response to images of food.. Intervention:. Twelve normal-weight male subjects were examined on two sessions in a counterbalanced fashion: after one night of total sleep deprivation and one night of sleep. On the morning after either total sleep deprivation or sleep, neural activation was measured by functional magnetic resonance imaging in a block design alternating between high- and low-calorie food items. Hunger ratings and morning fasting plasma glucose concentrations were assessed before the scan, as were appetite ratings in response to food images after ...
Improved Sleep a Benefit of Virta Diabetes Treatment - RTSleepWorldImproved Sleep a Benefit of Virta Diabetes Treatment - RTSleepWorld
14% and 21% decrease in their respective global PSQI scores. The proportion of Virta patients characterized as poor sleepers decreased by 12% and 29% in the type 2 diabetes and prediabetes groups, respectively. Patients who continued their usual care had no significant changes in self-reported sleep.. "Sleep has a substantial impact on the overall health of people with type 2 diabetes," said Dr. Christa Van Dort, Assistant Professor of Anesthesia at Harvard Medical School, the studys senior author. "With that in mind, it is promising that the Virta Treatment improved patients subjective sleep as indicated by significantly lower global PSQI scores in addition to improving their diabetes.". The Centers for Disease Control and Prevention has declared insufficient sleep a public health epidemic. T2D and obesity are frequently associated with poor sleep quality as well as obstructive sleep apnea (OSA), and improvement in sleep is associated with increased insulin sensitivity and glucose tolerance ...
Sleep Deprivation - Back to Wellness ChiropracticSleep Deprivation - Back to Wellness Chiropractic
Far too many Americans dont get enough sleep. When we feel pressed for time and have too much to do, we often sacrifice hours of sleep in order to cope. Maybe youre someone who actually boasts about how little sleep you need each night. But many of us dont understand just how vitally important that sleep is to our overall well-being. In fact, long-term sleep deprivation can be toxic to our health.. Without enough hours of sleep, we may wake up a little cranky and less focused than usual. But consistently getting insufficient sleep has larger, very real consequences to our physical health, too. Here are some of the harmful effects that sleep deprivation can have:. Lowered Immune Response. Studies report that people who arent getting enough sleep are at an increased chance of getting sick after being exposed to a virus. A persistent lack of sleep reduces the production of cytokines which are a type of protein that targets infection and inflammation.. Increased Risk of Type 2 Diabetes. Skimping ...
Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome.Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome.
BACKGROUND AND AIMS: Orexins/hypocretins are orexigenic peptides implicated in the regulation of feeding behavior and the sleep/wake cycle. Little is known about the functioning of these peptides in anorexia nervosa (AN). The aims of the current study were to evaluate the extent to which orexin-A might be linked to sleep and treatment outcome in AN.METHOD: Fasting plasma orexin-A concentrations were measured in 48 females with AN at the start of a day hospital treatment and in 98 normal-eater/healthy-weight controls. The Pittsburgh Sleep Quality Index was administered at the beginning of the treatment as a measure of sleep quality. Other psychopathological variables were evaluated with the Symptom Checklist-Revised (SCL90R) and the Eating Disorder Inventory-2 (EDI). Patients were assessed at the start and end of treatment by means of commonly used diagnostic criteria and clinical questionnaires.RESULTS: The AN patients presented more sleep disturbances and poorer overall sleep quality than did ...
Sleep paralysis - Sleep Medicine - Euroform HealthcareSleep paralysis - Sleep Medicine - Euroform Healthcare
This occurs occasionally in around 50% of normal subjects and frequently in around 6%, usually in adolescents and the elderly, especially with REM sleep rebound following sleep deprivation and jet lag following east-west travel which induces sleep-onset REM sleep. There is also a familial tendency to sleep paralysis.. Table 6.9 Differential diagnosis of cataplexy.. Sleep attack. Epilepsy, especially gelastic and atonic. Vertebro-basilar insufficiency. Cardiac dysrhythmias. Drop attacks. Myasthenia gravis. Periodic paralysis. Faints. Gelastic syncope Hysteria. Table 6.10 Differential diagnosis of vivid dreams in narcolepsy.. Sleep paralysis should be distinguished from the generalized fatigue on waking which is common in the chronic fatigue syndrome and depression and is due to a lack of motivation rather than true paralysis. This lasts longer than sleep paralysis and small movements, for instance of the fingers, are possible. Sleep paralysis may also be confused with atonic seizures, transient ...
Chicago, Illinois: Eliminate Atrial Fibrillation Caused Sleep Apnea with Comfortable Oral Appliances - Sleep and Health Journal...Chicago, Illinois: Eliminate Atrial Fibrillation Caused Sleep Apnea with Comfortable Oral Appliances - Sleep and Health Journal...
Atrial fibrillation can be caused by sleep apnea therefore 100% of patients with SAtrial Fibrillation should be evaluated for sleep apnea. Patients with Atrial Fibrillation should be tested even if they have none of the commonly seen symptoms of apnea such as snoring, excessive tirednedd, weight gain or hypertension. Many patients have sleep apnea but do not fit picture often associated with apnea. Unfortunately while the percentage of patients with sleep apnea in cardiology offices may be as high as 70% it is estimated only 10-20% are ever diagnosed. I have recently created a new company Sleep Well Illinois to set up UNIVERSAL SLEEP APNEA SCREENING IN CARDIOLOGY PRACTICES AND INTERNAL MEDICINE OFFICES. https://www.sleepandhealth.com/node/653. Universal screening for sleep apnea can be done with a simple questionnaire and at risk patients can have a portable sleep test in the comfort of their own home in their own bed. Most patients have mild to moderate sleep apnea and do not require CPAP. ...
Safe t sleep instructionsSafe t sleep instructions
Safe T Sleep Sleepwrap Babywrap Swaddle CLASSIC Model. Safe T Sleep Sleepwrap Babywrap Swaddle: CLASSIC Model Fits: Bassinets, Cribs/Cots, and Standard Single Beds, for Babies, Help PLEASE! How to stop using Safe T Sleep - posted in Sleeping: My 8 month DS has been wrapped in his Safe T Sleep since around 2 months of age and it has been. Safe T Sleep, Classic model This made all of us sleep easy! Although the instructions say hand wash only I was it on gentle cycle and dry on low heat and it You must check to make sure that it is safe for you to take Nytol (diphenhydramine (sleep Use Nytol (diphenhydramine (sleep aid) Follow all instructions closely.. Safe T Sleep Sleepwrap Classic Helps prevent flat heads, in combo with the little Safe T SleepHEADwedge, Safer co-sleeping, Allows natural, You must check to make sure that it is safe for you to take Nytol (diphenhydramine (sleep Use Nytol (diphenhydramine (sleep aid) Follow all instructions closely.. eco living friendly (elfbrands) green ...
The effect of yoga on sleep quality and insomnia in women with sleep problems: a systematic review and meta-analysis | BMC...The effect of yoga on sleep quality and insomnia in women with sleep problems: a systematic review and meta-analysis | BMC...
To examine the effectiveness and safety of yoga of women with sleep problems by performing a systematic review and meta-analysis. Medline/PubMed, ClinicalKey, ScienceDirect, Embase, PsycINFO, and the Cochrane Library were searched throughout the month of June, 2019. Randomized controlled trials comparing yoga groups with control groups in women with sleep problems were included. Two reviewers independently evaluated risk of bias by using the risk of bias tool suggested by the Cochrane Collaboration for programming and conducting systematic reviews and meta-analyses. The main outcome measure was sleep quality or the severity of insomnia, which was measured using subjective instruments, such as the Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), or objective instruments such as polysomnography, actigraphy, and safety of the intervention. For each outcome, a standardized mean difference (SMD) and confidence intervals (CIs) of 95% were determined. Nineteen studies in this systematic
Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver...Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver...
BACKGROUND & AIMS: Sleep disturbance is associated with the development of obesity, diabetes and hepatic steatosis in murine models. Hepatic triglyceride accumulation oscillates in a circadian rhythm regulated by clock genes, light-dark cycle and feeding time in mice. The role of the sleep-wake cycle in the pathogenesis of human non-alcoholic fatty liver disease (NAFLD) is indeterminate. We sought to detail sleep characteristics, daytime sleepiness and meal times in relation to disease severity in patients with NAFLD. METHODS: Basic Sleep duration and latency, daytime sleepiness (Epworth sleepiness scale), Pittsburgh sleep quality index, positive and negative affect scale, Munich Chronotype Questionnaire and an eating habit questionnaire were assessed in 46 patients with biopsy-proven NAFLD and 22 healthy controls, and correlated with biochemical and histological parameters. RESULTS: In NAFLD compared to healthy controls, time to fall asleep was vastly prolonged (26.9 vs. 9.8 min., p = ...
Its A Dreamers World: Sleep ParalysisIt's A Dreamer's World: Sleep Paralysis
During sleep, your body alternates between REM (rapid eye movement) and NREM (non-rapid eye movement) sleep. One cycle of REM and NREM sleep lasts about 90 minutes. NREM sleep occurs first and takes up to 75% of your overall sleep time. During NREM sleep, your body relaxes and restores itself. At the end of NREM, your sleep shifts to REM. Your eyes move quickly and dreams occur, but the rest of your body remains very relaxed. Your muscles are "turned off" during REM sleep. If you become aware before the REM cycle has finished, you may notice that you cannot move or speak ...
Sleep Apnea - World Sleep FoundationSleep Apnea - World Sleep Foundation
Sleep apnea is a common disorder in which breathing stops during sleep for 10 seconds or more, sometimes more than 300 times a night. The hallmark of the disorder is excessive daytime sleepiness and compromised quality of life, including significant social and emotional problems. There are two main types of sleep apnea. "Obstructive sleep apnea" may represent cessation of breathing due to mechanical blockage of the airway; "central sleep apnea" appears to be related to a malfunction of the brains normal signal to breathe. Symptoms of sleep apnea may include restless sleep, loud, heavy snoring (often interrupted by silence and then gasps), falling asleep while driving and/or during the day (at work, watching TV, etc.), morning headaches, loss of energy, trouble concentrating, irritability, forgetfulness, mood or behavior changes, anxiety or depression, obesity, and decreased interest in sex. Not all people with sleep apnea experience all of these symptoms and not everyone who has these symptoms ...
Snoring | Redwood City Sleep Apnea Dentist | Dr. Mark AbramsonSnoring | Redwood City Sleep Apnea Dentist | Dr. Mark Abramson
Snoring and Sleep Apnea are very often linked. Sleep Apnea Syndromes by nature affect how one breathes in sleep. Because of this, many peoples bed partners will have witnessed different breathing patterns that will result in further evaluation for sleep apnea conditions. Snoring is the most common respiratory disturbance in sleep. It results from a partial airway obstruction that serves as a "whistle" causing the snoring noises. Snoring however does not confirm Obstructive Sleep Apnea syndrome, however, as snoring can exist without any sleep disruption, apneas, or hypopneas. The important point is that if a partial obstruction exists and is causing snoring, then the same obstruction may be causing a sleep apnea condition.. Other breathing patterns that are described during sleep include actual periods where the individual is noted to pause in breathing. Also, gasping for air after a pause is common, and can be frightening for the observer. Noises can range from a soft snore to a coarse loud ...
Acute Sleep Restriction Reduces Insulin Sensitivity in Adolescent BoysAcute Sleep Restriction Reduces Insulin Sensitivity in Adolescent Boys
Background: Short sleep duration has been linked to impaired glucose metabolism in many experimental studies. Moreover, studies have reported indications of an increased metabolic stress following sleep restriction. Objective: We aimed to investigate the effects of partial sleep deprivation on markers of glucose metabolism. Additionally, we aimed to investigate if short sleep duration induces a state of endocrine stress. Design: A randomized crossover design, with 2 experimental conditions: 3 consecutive nights of short sleep (SS, 4 h/night) and long sleep (LS, 9 h/night) duration. Subjects and Measurements: In 21 healthy, normal-weight male adolescents (mean +/- SD age: 16.8 +/- 1.3 y) we measured pre- and post-prandial glucose, insulin, C-peptide, and glucagon concentrations. Furthermore, we measured fasting cortisol, 24-h catecholamines, and sympathovagal balance. Results: Fasting insulin was 59% higher (P = 0.001) in the SS than the LS condition as was both fasting (24%, P , 0.001) and ...
Poor Sleep Quality and Progression of Gait Impairment in an Incident Parkinsons Disease Cohort - ePrints - Newcastle UniversityPoor Sleep Quality and Progression of Gait Impairment in an Incident Parkinson's Disease Cohort - ePrints - Newcastle University
Abnormal sleep may associate with cognitive decline in Parkinsons disease (PD). Furthermore, sleep dysfunction may associate with worse motor outcome. We hypothesised that PD patients with poor quality sleep would have greater progression in gait dysfunction, due to structural and functional overlap in networks subserving sleep and gait regulation. 12 PD patients and 12 age-matched controls completed longitudinal follow-up over 36 months. Poor sleep efficiency and greater sleep fragmentation correlated significantly with progression of step-width variability, a gait characteristic mediated by postural control, providing evidence that poor sleep in PD is associated with a more rapid deterioration in gait.. ...
The Debate Over Sleep Apnea Treatment | Fire Station 8The Debate Over Sleep Apnea Treatment | Fire Station 8
Occasionally its possible to have sleep apnea prior to being conscious of it. Sleep apnea is significantly more serious than many realize. Severe sleep apnea can triple your odds of stroke.. Sleep Apnea is extremely common among American adults. It is a major sleep disorder wherein a person abruptly wakes up in the middle of sleep because of blockage in the airway. While its not normally thought of as a serious disease it can have a very negative impact on your life and,if left untreated,could lead to death. If youre aware that you have got sleep apnea,or even suspect that,then speak to your physician about assembling a sleep study so you can get fitted for a CPAP. Therefore,in case you have severe sleep apnea and other therapies have not helped,you want to be certain to speak with your healthcare provider about operation as a possible choice.. } Staying at a wholesome weight is 1 approach to reduce apnea. Sleeping apnea is just among the most frequently encountered problems prevailing around ...
A Combined Sleep Hygiene and Mindfulness Intervention to Improve Sleep and Well-Being During High-Performance Youth Tennis...A Combined Sleep Hygiene and Mindfulness Intervention to Improve Sleep and Well-Being During High-Performance Youth Tennis...
Purpose: To investigate the effects of combined sleep hygiene recommendations and mindfulness on actigraphy-based sleep parameters, perceptual well-being, anxiety, and match outcomes during high-performance junior tennis tournaments. Methods: In a randomized crossover design, 17 high-performance junior tennis players completed the baseline, control, and intervention (INT) conditions across 3 separate weeks. The baseline consisted of unassisted, habitual sleep during a regular training week, and the control was unassisted sleep during a tournament week. The players attended a sleep education workshop and completed a nightly sleep hygiene protocol during a tournament week for the INT. Analysis was performed on the weekly means and on the night prior to the first match of the tournament (T-1). Results: Significant differences were observed for increased time in bed, total sleep time, and an earlier bedtime (P , .05) across the INT week. These parameters also significantly improved on T-1 of the ...
The clinical relevance of early identification and treatment of sleep disorders in mental health care: protocol of a randomized...The clinical relevance of early identification and treatment of sleep disorders in mental health care: protocol of a randomized...
Sleep disorders are a risk factor for developing a variety of mental disorders, have a negative impact on their remission rates and increase the risk of relapse. Early identification and treatment of sleep disorders is therefore of paramount importance. Unfortunately, in mental health care sleep disorders are often poorly recognized and specific treatment frequently occurs late or not at all. This protocol-paper presents a randomized controlled trial investigating the clinical relevance of early detection and treatment of sleep disorders in mental health care. The two aims of this project are 1) to determine the prevalence of sleep disorders in different mental disorders, and 2) to investigate the contribution of early identification and adequate treatment of sleep disorders in individuals with mental disorders to their sleep, mental disorder symptoms, general functioning, and quality of life. Patients newly referred to a Dutch mental health institute for psychiatric treatment will be screened for sleep
Psychometric properties of the Adolescent Sleep Hygiene Scale - Storfer-Isser - 2013 - Journal of Sleep Research - Wiley Online...Psychometric properties of the Adolescent Sleep Hygiene Scale - Storfer-Isser - 2013 - Journal of Sleep Research - Wiley Online...
Evidence-based assessment of the psychometric properties of available paediatric sleep instruments is needed (Lewandowski et al., 2011; Spruyt and Gozal, 2011). The current study examined the factor structure, internal consistency reliability and concurrent validity of the ASHS using a community-based urban sample of 16-19-year-old adolescents. The empirical factor structure of the revised 24-item scale (ASHSr) is largely consistent with the theoretically based structure proposed initially (LeBourgeois et al., 2005), with the exceptions that the cognitive and emotional domains were combined into one factor and a new behavioural arousal construct was identified. Internal consistency reliability of the ASHSr as well as concurrent validity with objective measures of sleep and convergent validity with behavioural outcomes indicate that the ASHSr has satisfactory psychometric properties for a research instrument to assess adolescent sleep hygiene.. Sleep hygiene was correlated modestly with objective ...
Music for sleep - Music and Wellbeing - Projects - Music and Wellbeing - Research Centres - Research - Music - The University...Music for sleep - Music and Wellbeing - Projects - Music and Wellbeing - Research Centres - Research - Music - The University...
The power of music to aid sleep is evidenced in the existence of music for sleep CDs and radio stations. Despite their popularity, there is little evidence-based research on how sleep quantity or quality is impacted by music.. In particular, no study to date has combined music with sleep measures for long enough to be effective and most studies take place in hospitals not in peoples own beds.. Our research will redress this situation by first, carrying out a large-scale Internet survey on music and sleep, to determine how people are currently using music when they encounter sleep difficulties in their day-to-day life. Using the results of this survey we will then carry out an informed, long-term music for sleep intervention study in peoples own homes using new sleep monitoring technologies.. Our research team combines different expertise to explore new pathways to impact for music and sleep research. We also aim to train postgraduate students in the UK in the use of sleep technologies and ...
Hypnogram - WikipediaHypnogram - Wikipedia
A hypnogram is a form of polysomnography; it is a graph that represents the stages of sleep as a function of time. It was developed as an easy way to present the recordings of the brain wave activity from an electroencephalogram (EEG) during a period of sleep. It allows the different stages of sleep: rapid eye movement sleep (REM) and non-rapid eye movement sleep (NREM) to be identified during the sleep cycle. NREM sleep can be further classified into NREM stage 1, 2 and 3. The previously considered 4th stage of NREM sleep has been included within stage 3; this stage is also called slow wave sleep (SWS) and is the deepest stage of sleep. Each of the three NREM stages as well as the period of REM sleep and the awake state can be determined and displayed on a hypnogram. Hypnograms are usually obtained by visually scoring the recordings from electroencephalogram (EEGs), electrooculography (EOGs) and electromyography (EMGs). The output from these three sources is recorded simultaneously on a graph ...
Sleep Disorders | Mercy Health | Toledo, OHSleep Disorders | Mercy Health | Toledo, OH
Our Childrens Sleep Disorders Program is the only program in Northwest Ohio to provide comprehensive diagnosis, treatment, consultation and referral for children with sleep disorders such as sleep apnea, sleepwalking, insomnia, disturbed sleep/wake rhythms, nocturnal seizures and bedwetting. Our team approach includes professionals in pediatric pulmonology, specialists in psychology and development, and pediatric sleep specialists.. Diagnostic Services. Polysomnographic evaluation at either the Mercy Health - St. Anne Sleep Center or the Mercy Health - St. Charles Sleep Center. Both Centers are fully accredited by the American Academy of Sleep Medicine insuring that they adhere to the highest standards of professional care ...
Sleep ApneaSleep Apnea
your life.. So what is the difference between snoring and and Apnea? Sleep Apnea is a breathing obstruction which would require the individual to wake up in order to breathe again. Snoring is just simply a loud noise a person makes while sleeping. If you experience sleep apnea, you would usually wake up at nights to regain breathing but have no recollection about them the next morning.. Common signs of this disease are disrupted breathing, gagging and gasping during sleep and frequent episodes of waking during the night. Usually a diagnosis is made after the bed partner provides the information to the doctor about the sleeping disorder so that the doctor can make a diagnosis on the individual.. During diagnosis, a doctor will perform an exam of your mouth and most likely recommend a sleep study at a clinic to do some monitoring.. The 3 types of sleep apnea that exist are: Obstructive Sleep Apnea, Central Sleep Apnea and Mixed Sleep Apnea.. Causes of this disorder are obstructed airways, chronic ...
sleep disorder - madieas blogsleep disorder - madiea's blog
sleep disorder centers des moines ia sleep apnea aids central apnea sleep disorders in adults dr. maas sleep disorders stop snoring hypnosis sleep disorder child sleep disorder questionnaire sleep disorders uk ways to stop snoring Sleep disorders can be effectively treated or managed once correctly diagnosed . Using Research and...
SLEEP DEPRIVATION IN THE SUMMER - The Leader NewspaperSLEEP DEPRIVATION IN THE SUMMER - The Leader Newspaper
The heat and the longer hours of sunshine are the main causes for sleep deprivation. For that reason many people turn to sleeping with air conditioning, open windows or use fans that also provide good benefits for a healthy sleep, as say the experts at the Sleep Unit of Hospital Quirónsalud Murcia, Torrevieja and Valencia. According to Dr. Gonzalo Pin, coordinator of the Sleep Unit for Hospital Quirónsalud Valencia, in summer there are four circumstances that could affect our sleep, in the case of high summer temperatures, "if the temperature is greater than 22 degrees the onset of sleep is difficult therefore more movements and night time awakenings. Also the increased noise levels from outside when we open windows, more people on the street, the noise from the air conditioning machine etc. Our hearing is in "waking activity" hindering the depth and continuity of our sleep.". The second cause that affects our sleep in the summer is the duration of light-dark natural cycle: as the daylight ...
Ventrolateral preoptic nucleus - WikipediaVentrolateral preoptic nucleus - Wikipedia
The ventrolateral preoptic nucleus (VLPO), also known as the intermediate nucleus of the preoptic area (IPA), is a small cluster of neurons situated in the anterior hypothalamus, sitting just above and to the side of the optic chiasm in the brain of humans and other animals. The VLPO, together with the reticular activating system and the widely projecting orexin neuronal system that originates in the lateral hypothalamus, are the interconnected neural systems which control states of arousal, sleep, and transitions between these two states. The VLPO is active during sleep, primarily during non-rapid eye movement sleep (NREM sleep), and releases inhibitory neurotransmitters, mainly GABA and galanin, which inhibit neurons of the reticular activating system that are involved in wakefulness and arousal. The VLPO is in turn innervated by neurons from the aforementioned neural systems. The VLPO is activated by the sleep-inducing neurotransmitters serotonin and adenosine and endosomnogen Prostaglandin ...
Incident diabetes mellitus may explain the association between sleep duration and incident coronary heart diseaseIncident diabetes mellitus may explain the association between sleep duration and incident coronary heart disease
article{f963b6fc-e756-4df4-ac43-a0f6062f09ae, abstract = {,p,Aims/hypothesis: Sleep duration is a risk factor for incident diabetes mellitus and CHD. The primary aim of the present study was to investigate, in sex-specific analyses, the role of incident diabetes as the possible biological mechanism for the reported association between short/long sleep duration and incident CHD. Considering that diabetes is a major risk factor for CHD, we hypothesised that any association with sleep duration would not hold for cases of incident CHD occurring before incident diabetes (non-diabetes CHD) but would hold true for cases of incident CHD following incident diabetes (diabetes-CHD). Methods: A total of 6966 men and 9378 women aged 45-73 years from the Malmö Diet Cancer Study, a population-based, prospective cohort, who had answered questions on habitual sleep duration and did not have a history of prevalent diabetes or CHD were included in the analyses. Incident cases of diabetes and CHD were ...
Sleep Disruption Among Older Men and Risk of Prostate Cancer | Cancer Epidemiology, Biomarkers & PreventionSleep Disruption Among Older Men and Risk of Prostate Cancer | Cancer Epidemiology, Biomarkers & Prevention
In this prospective cohort study, we found that men with sleep disruption were at increased risk of prostate cancer, particularly advanced prostate cancer, when compared with men who did not report any sleep problems.. The association between sleep disruption and prostate cancer was stronger for advanced disease than for overall prostate cancer. This may be a chance finding due to limited number of cases in the analyses for advanced cases. It is also possible that underlying mechanisms of sleep disturbance, such as circadian disruption and reduced melatonin levels, affect prostate cancer progression to a greater extent than prostate cancer initiation (19). Nonetheless, our data support the hypothesis that some aspect related to sleep disruption may confer an increased risk of prostate cancer.. Most epidemiologic studies to date on the effect of sleep or circadian rhythm disruption have focused on the impact of shift work on cancer risk. Consistent with the hypotheses for sleep disruption, 4 ...
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AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
SleepSleep, REMSleep DisordersSleep Apnea, ObstructiveSleep Apnea SyndromesSleep Initiation and Maintenance DisordersPolysomnographyWakefulnessElectroencephalographyActigraphyArousalSleep Apnea, CentralCircadian RhythmDisorders of Excessive SomnolenceSleep BruxismSleep Disorders, IntrinsicElectrooculographySleep Medicine SpecialtySleep Arousal DisordersSnoringNarcolepsyDelta RhythmSleep ParalysisDreamsREM Sleep Behavior DisorderNocturnal Myoclonus SyndromeContinuous Positive Airway PressureElectromyographyQuestionnairesTime FactorsFatigueHypnotics and SedativesHabitsMelatoninSeverity of Illness IndexCataplexyRestless Legs SyndromeAnalysis of VarianceSleep Phase ChronotherapyRespirationBody TemperatureCross-Sectional StudiesMandibular AdvancementSomnambulismAdenoidectomyTonsillectomyPharynxUvulaHomeostasisPonsPalate, SoftBrain WavesActivity CyclesAzabicyclo CompoundsRisk FactorsComorbidityChronobiology DisordersPositive-Pressure RespirationPrevalenceBody Mass IndexMonitoring, AmbulatoryCross-Over StudiesPharyngeal MusclesBrainRespiratory Mechanics
ApneaDeprivationDisorderDisturbanceDurationAsleepWakefulnessDaytimeDisturbancesNight'sHabitsChronicPrevalenceBehaviorLatencyPatternsAdultsBehaviorsDisruptionNREMAbstractOccursCentersStudyNightPolysomnographyAffectsDifficultyTimeQualityPediatricStagesCyclesProblemsCycleConsistentTreatmentBehavioralRapidPatients
Apnea28
Deprivation3
Disorder2
Disturbance1
Duration1
Asleep6
  • In this sample, 11.5% of participants met the criteria for Delayed Sleep Phase Syndrome as indicated by late sleep onset times, little or no difficulty staying asleep, and significantly later sleep and awakening times during the weekend than during the week. (thefreedictionary.com)
  • The specialist uses your sleep history to evaluate symptoms such as difficulty falling asleep, difficulty staying asleep, daytime sleepiness or fatigue, breathing problems during sleep, restless legs at night and other various troublesome behaviors. (providence.org)
  • Before you fall asleep, the sleep technologist will place the CPAP mask and make sure it is a comfortable fit. (providence.org)
  • Individuals who experience excessive daytime sleepiness or who fall asleep at inappropriate times may be referred by their physician to a sleep center for a Multiple Sleep Latency Test or a Maintenance of Wakefulness Test. (providence.org)
  • Develop environmental cues to help you associate bed-time and your bed with sleep, for example: Do not use your bed as an activity centre, No TV in bed room Go to bed only when you are sleepy If you don't fall asleep within 10 - 15 minutes, get out of bed and go into another room. (speakingtree.in)
  • Do not return to bed until you are sleepy Repeat as often as necessary until you fall asleep within 15 - 20 minutes Get up the same time each morning, regardless of how little sleep you had. (speakingtree.in)
Wakefulness1
  • The results presented here suggest that NE promotes wakefulness during transitions between sleep and wake under conditions involving mild stress and SD, but not under baseline circumstances. (modafinil.com)
Daytime1
  • Having a late sleep pattern puts you at odds with the standard societal days, which can lead to a range of adverse outcomes - from daytime sleepiness to poorer mental wellbeing," study co-author Dr Andrew Bagshaw said. (thefreedictionary.com)
Disturbances1
  • Studies have shown that following a Mediterranean diet plus exercise can reduce sleep disturbances in those with OSA during the rapid eye movement stage of sleep, which accounts for about 25% of sleep time. (whittierdailynews.com)
Night's2
Habits1
Chronic2
Prevalence2
Behavior1
Latency7
Patterns3
  • A sleep study, or Polysomnogram (PSG), is an overnight recording of sleep patterns and behaviors associated with sleep. (providence.org)
  • During these naps, a sleep technologist monitors the patient's sleep/wake patterns. (providence.org)
  • In his book, Walker, who heads up U.C. Berkeley's Center for Human Sleep Science, dives into his own research into sleep as well as the work of others with the aim of finding answers to questions like what really happens during REM sleep, and how substances like alcohol and caffeine affect our sleep patterns. (scpr.org)
Adults1
  • Numerous studies have documented the potential health benefits of the Mediterranean diet in the general population, which include better sleep quality among normal weight and overweight adults. (whittierdailynews.com)
Behaviors1
Disruption1
NREM1
  • Arousal threshold was measured by recording the number of decibels of white noise required to wake each mouse from NREM sleep after 0, 3 and 3 + 3 h SD (3 h SD followed by (modafinil.com)
Abstract1
  • abstract = "Genetic determinants may contribute to the large variability in arterial blood pressure responses to changes in sleep/wake state in humans. (elsevier.com)
Occurs1
  • REM Sleep : This occurs about 90 minutes after Stage 1 of Non-REM Sleep and reoccurs every 90 minutes. (speakingtree.in)
Centers2
  • As with most centers who are accredited by the American Academy of Sleep Medicine, there is always a physician on call at night for the technologists and there are two patients per one technologist. (ocregister.com)
  • Our sleep centers are set up like bedrooms and are furnished with select comfort beds. (providence.org)
Study10
Night8
  • However, some patients may return for a treatment visit if they had trouble sleeping the first night and we were unable to establish an effective therapy. (ocregister.com)
  • A trained sleep technologist explains the procedure, operates the diagnostic equipment and is stationed all night in an adjacent control room. (providence.org)
  • This waking is often a pattern of snoring, choking and gasping that can last all night, leading to poor quality sleep. (whittierdailynews.com)
  • However, many people experience problems getting to sleep, waking in the middle of the night, or waking early and not being able to get back to sleep. (speakingtree.in)
  • We move in and out of between 4 and 5 cycles of specific sleep stages each night. (speakingtree.in)
  • Overall 25% of our night-time sleeping is spent in REM sleep. (speakingtree.in)
  • Studies have shown that napping cannot substitute for a solid night of good sleep. (speakingtree.in)
  • The ability to sleep through the night usually does not develop until at least 3 to 6 months of age. (aappublications.org)
Polysomnography1
  • The animals were then allowed to cycle naturally through sleep/wake states over a 3- to 4-h period while continuous polysomnography and arterial pressure measurements were made. (elsevier.com)
Affects1
  • During the holy month, the drivers may suffer from fatigue because of late sleep , which directly affects their attention, focus and the ability to control the vehicle. (thefreedictionary.com)
Difficulty1
Time4
  • Having a late sleep pattern puts you at odds with the standard societal days, which can lead to a range of adverse outcomes-from day time sleepiness to poorer mental well-being" (https://www.medicalnewstoday.com/articles/325429.php) explained Andrew Bagshaw, Ph.D. (thefreedictionary.com)
  • Develop a routine of going to sleep and waking up the same time every day. (speakingtree.in)
  • A consistent wake-up time will help your body develop a regular sleep pattern Do not nap. (speakingtree.in)
  • Establish a regular bed-time routine so that your body knows that you are going to sleep. (speakingtree.in)
Quality1
  • Further high-quality research is required to determine whether there is a true difference in sleep between those with and without PTSD. (ntvp.nl)
Pediatric1
Stages2
  • Sleep studies help determine what stages of sleep an individual achieves and whether any sleep-related abnormalities are present. (providence.org)
  • An individual can go through stages of sleep such as mild sleep to deep sleep states, but in between the sleep cycles, there are sleep disorders than an individual might experience, yet be completely unaware of it. (humehealth.com.au)
Cycles1
  • As you progress through cycles of NON-REM and REM sleep, deep sleep becomes increasingly shorter and REM sleep becomes increasingly longer (it is longest after 12pm), which is why you can often recall dreams just after waking. (speakingtree.in)
Problems2
Cycle2
Consistent2
Treatment1
  • The findings are integrated with your sleep history to determine a diagnosis and make the appropriate treatment recommendations. (providence.org)
Behavioral1
Rapid1
  • Non-REM (Rapid Eye Movement) Sleep Stage 1 - During this stage you become drowsy, your thoughts become incoherent and you may feel like your are floating or falling. (speakingtree.in)
Patients1
Neuroscience of sleep - Wikipedia
Neuroscience of sleep - Wikipedia (en.wikipedia.org)
How to sleep better: 37 hacks - CNN
How to sleep better: 37 hacks - CNN (cnn.com)
Lack of sleep may shrink your brain - CNN
Lack of sleep may shrink your brain - CNN (cnn.com)
Sleep apnea: Treatment is crucial, experts say - CNN
Sleep apnea: Treatment is crucial, experts say - CNN (cnn.com)
Dreamlight: The World's Smartest Sleep Mask | Indiegogo
Dreamlight: The World's Smartest Sleep Mask | Indiegogo (indiegogo.com)
Amazfit ZenBuds: Fit Right, Sleep Tight | Indiegogo
Amazfit ZenBuds: Fit Right, Sleep Tight | Indiegogo (indiegogo.com)
Neuroon Open: World's Smartest Sleep Tracker | Indiegogo
Neuroon Open: World's Smartest Sleep Tracker | Indiegogo (indiegogo.com)
Beddit - Automatic sleep and wellness tracker. | Indiegogo
Beddit - Automatic sleep and wellness tracker. | Indiegogo (indiegogo.com)
Circular Smart Ring: Sleep, Energy, Performance. | Indiegogo
Circular Smart Ring: Sleep, Energy, Performance. | Indiegogo (indiegogo.com)
Disruptive Sleep Disorder Affects the Left-Handed Differently
Disruptive Sleep Disorder Affects the Left-Handed Differently (livescience.com)
Matt Walker: Sleep is your superpower | TED Talk
Matt Walker: Sleep is your superpower | TED Talk (ted.com)
Russell Foster: Why do we sleep? | TED Talk
Russell Foster: Why do we sleep? | TED Talk (ted.com)
Sleep Review - April 2013 digital edition
Sleep Review - April 2013 digital edition (edition.pagesuite-professional.co.uk)
Love ASMR Colors Relax & Sleep Now 😴💤15min🙏 ZEN Music - YouTube
Love ASMR Colors Relax & Sleep Now 😴💤15min🙏 ZEN Music - YouTube (youtube.com)
Critical Care, Pulmonary and Sleep Associates Careers | Monster.com
Critical Care, Pulmonary and Sleep Associates Careers | Monster.com (monster.com)
Aging Americans Sleep More, Work Less, Survey Finds - WSJ
Aging Americans Sleep More, Work Less, Survey Finds - WSJ (wsj.com)
MGM Signature Luxury Suite StripView (Sleep... - HomeAway
MGM Signature Luxury Suite StripView (Sleep... - HomeAway (homeaway.com)
Drug InfoNet - Actos - [sleep-disorder]
Drug InfoNet - Actos - [sleep-disorder] (druginfonet.com)
Pauole: 2 BR / 1 BA house in Hanalei, Sleep... - VRBO
Pauole: 2 BR / 1 BA house in Hanalei, Sleep... - VRBO (vrbo.com)
Arianna Huffington: How to succeed? Get more sleep | TED Talk
Arianna Huffington: How to succeed? Get more sleep | TED Talk (ted.com)
How to Sleep Your Way to Weight Loss
How to Sleep Your Way to Weight Loss (lifehack.org)
Pre-existing conditions: Pregnancy, sleep apnea could make you pay more - CNN
Pre-existing conditions: Pregnancy, sleep apnea could make you pay more - CNN (cnn.com)
Manila ph cityguide sleep
Manila ph cityguide sleep (toryburch.com)
Why so many people sleep in McDonald's in Hong Kong - CNN
Why so many people sleep in McDonald's in Hong Kong - CNN (edition.cnn.com)
Sleep Music 安心舒眠 - playlist by Filtr Taiwan | Spotify
Sleep Music 安心舒眠 - playlist by Filtr Taiwan | Spotify (open.spotify.com)
Myths about baby sleep and SIDS, debunked by an expert - CNN
Myths about baby sleep and SIDS, debunked by an expert - CNN (edition.cnn.com)
Lavender & Acacia Good Night Sleep Pillow Mist
Lavender & Acacia Good Night Sleep Pillow Mist (ulta.com)
Sleep positions during pregnancy - American Pregnancy Association
Sleep positions during pregnancy - American Pregnancy Association (americanpregnancy.org)
Nothing much happens; bedtime stories to help you sleep | Podcast on Spotify
Nothing much happens; bedtime stories to help you sleep | Podcast on Spotify (open.spotify.com)
Kids' pajama set in sheep : Girl sleep sets | J.Crew
Kids' pajama set in sheep : Girl sleep sets | J.Crew (jcrew.com)
Does Vitamin C Affect Your Sleep? | Livestrong.com
Does Vitamin C Affect Your Sleep? | Livestrong.com (livestrong.com)
Girodet, The Sleep of Endymion (video) | Khan Academy
Girodet, The Sleep of Endymion (video) | Khan Academy (khanacademy.org)