AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
SinusitisMaxillary SinusitisSphenoid SinusitisEthmoid SinusitisFrontal SinusitisParanasal SinusesMaxillary SinusParanasal Sinus DiseasesEthmoid SinusOrbital DiseasesRhinitisTransilluminationBacteria, AerobicEndoscopyNasal PolypsCellulitisMycosesTomography Scanners, X-Ray ComputedAcute DiseaseNose DiseasesOtorhinolaryngologic Surgical ProceduresAmoxicillin-Potassium Clavulanate CombinationOtitisFrontal SinusNasal MucosaTurbinatesRespiratory Tract InfectionsExophthalmosMucoceleMucormycosisSphenoid SinusAspergillosisChronic DiseaseCiliary Motility DisordersOroantral FistulaCavernous Sinus ThrombosisAnti-Bacterial AgentsLaryngitisBacterial InfectionsTomography, X-Ray ComputedPorphyromonasEthmoid BoneRhinitis, Allergic, PerennialNasal DecongestantsSchizophyllumOtitis MediaBrain AbscessEpidural AbscessTrichosporonosisStomatognathic DiseasesEmpyema, SubduralCommon ColdParanasal Sinus NeoplasmsTonsillitisBacteria, AnaerobicRhizopusNasal ObstructionKartagener SyndromeNasal SeptumCefuroximeCyclacillinMoraxella (Branhamella) catarrhalisAmoxicillinIntubation, Gastrointestinal
Sinusitis
Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.
Maxillary Sinusitis
Inflammation of the NASAL MUCOSA in the MAXILLARY SINUS. In many cases, it is caused by an infection of the bacteria HAEMOPHILUS INFLUENZAE; STREPTOCOCCUS PNEUMONIAE; or STAPHYLOCOCCUS AUREUS.
Sphenoid Sinusitis
Inflammation of the NASAL MUCOSA in the SPHENOID SINUS. Isolated sphenoid sinusitis is uncommon. It usually occurs in conjunction with other paranasal sinusitis.
Ethmoid Sinusitis
Inflammation of the NASAL MUCOSA in the ETHMOID SINUS. It may present itself as an acute (infectious) or chronic (allergic) condition.
Frontal Sinusitis
Inflammation of the NASAL MUCOSA in the FRONTAL SINUS. In many cases, it is caused by an infection of the bacteria STREPTOCOCCUS PNEUMONIAE or HAEMOPHILUS INFLUENZAE.
Paranasal Sinuses
Air-filled spaces located within the bones around the NASAL CAVITY. They are extensions of the nasal cavity and lined by the ciliated NASAL MUCOSA. Each sinus is named for the cranial bone in which it is located, such as the ETHMOID SINUS; the FRONTAL SINUS; the MAXILLARY SINUS; and the SPHENOID SINUS.
Maxillary Sinus
The air space located in the body of the MAXILLARY BONE near each cheek. Each maxillary sinus communicates with the middle passage (meatus) of the NASAL CAVITY on the same side.
Paranasal Sinus Diseases
Diseases affecting or involving the PARANASAL SINUSES and generally manifesting as inflammation, abscesses, cysts, or tumors.
Ethmoid Sinus
The numerous (6-12) small thin-walled spaces or air cells in the ETHMOID BONE located between the eyes. These air cells form an ethmoidal labyrinth.
Orbital Diseases
Diseases of the bony orbit and contents except the eyeball.
Rhinitis
Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.
Transillumination
Passage of light through body tissues or cavities for examination of internal structures.
Bacteria, Aerobic
Endoscopy
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
Nasal Polyps
Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.
Cellulitis
An acute, diffuse, and suppurative inflammation of loose connective tissue, particularly the deep subcutaneous tissues, and sometimes muscle, which is most commonly seen as a result of infection of a wound, ulcer, or other skin lesions.
Mycoses
Tomography Scanners, X-Ray Computed
X-ray image-detecting devices that make a focused image of body structures lying in a predetermined plane from which more complex images are computed.
Acute Disease
Disease having a short and relatively severe course.
Nose Diseases
Disorders of the nose, general or unspecified.
Otorhinolaryngologic Surgical Procedures
Surgery performed on the ear and its parts, the nose and nasal cavity, or the throat, including surgery of the adenoids, tonsils, pharynx, and trachea.
Amoxicillin-Potassium Clavulanate Combination
A fixed-ratio combination of amoxicillin trihydrate and potassium clavulanate.
Otitis
Inflammation of the ear, which may be marked by pain (EARACHE), fever, HEARING DISORDERS, and VERTIGO. Inflammation of the external ear is OTITIS EXTERNA; of the middle ear, OTITIS MEDIA; of the inner ear, LABYRINTHITIS.
Frontal Sinus
One of the paired, but seldom symmetrical, air spaces located between the inner and outer compact layers of the FRONTAL BONE in the forehead.
Nasal Mucosa
The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells.
Turbinates
The scroll-like bony plates with curved margins on the lateral wall of the NASAL CAVITY. Turbinates, also called nasal concha, increase the surface area of nasal cavity thus providing a mechanism for rapid warming and humidification of air as it passes to the lung.
Respiratory Tract Infections
Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
Exophthalmos
Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye.
Mucocele
A retention cyst of the salivary gland, lacrimal sac, paranasal sinuses, appendix, or gallbladder. (Stedman, 26th ed)
Mucormycosis
Infection in humans and animals caused by any fungus in the order Mucorales (e.g., Absidia, Mucor, Rhizopus etc.) There are many clinical types associated with infection of the central nervous system, lung, gastrointestinal tract, skin, orbit and paranasal sinuses. In humans, it usually occurs as an opportunistic infection in patients with a chronic debilitating disease, particularly uncontrolled diabetes, or who are receiving immunosuppressive agents. (From Dorland, 28th ed)
Sphenoid Sinus
One of the paired air spaces located in the body of the SPHENOID BONE behind the ETHMOID BONE in the middle of the skull. Sphenoid sinus communicates with the posterosuperior part of NASAL CAVITY on the same side.
Aspergillosis
Infections with fungi of the genus ASPERGILLUS.
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Ciliary Motility Disorders
Conditions caused by abnormal CILIA movement in the body, usually causing KARTAGENER SYNDROME, chronic respiratory disorders, chronic SINUSITIS, and chronic OTITIS. Abnormal ciliary beating is likely due to defects in any of the 200 plus ciliary proteins, such as missing motor enzyme DYNEIN arms.
Oroantral Fistula
A fistula between the maxillary sinus and the oral cavity.
Cavernous Sinus Thrombosis
Formation or presence of a blood clot (THROMBUS) in the CAVERNOUS SINUS of the brain. Infections of the paranasal sinuses and adjacent structures, CRANIOCEREBRAL TRAUMA, and THROMBOPHILIA are associated conditions. Clinical manifestations include dysfunction of cranial nerves III, IV, V, and VI, marked periorbital swelling, chemosis, fever, and visual loss. (From Adams et al., Principles of Neurology, 6th ed, p711)
Anti-Bacterial Agents
Substances that reduce the growth or reproduction of BACTERIA.
Laryngitis
Inflammation of the LARYNGEAL MUCOSA, including the VOCAL CORDS. Laryngitis is characterized by irritation, edema, and reduced pliability of the mucosa leading to VOICE DISORDERS such as APHONIA and HOARSENESS.
Bacterial Infections
Infections by bacteria, general or unspecified.
Tomography, X-Ray Computed
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Porphyromonas
A genus of gram-negative, anaerobic, nonsporeforming, nonmotile rods or coccobacilli. Organisms in this genus had originally been classified as members of the BACTEROIDES genus but overwhelming biochemical and chemical findings indicated the need to separate them from other Bacteroides species, and hence, this new genus was created.
Ethmoid Bone
A light and spongy (pneumatized) bone that lies between the orbital part of FRONTAL BONE and the anterior of SPHENOID BONE. Ethmoid bone separates the ORBIT from the ETHMOID SINUS. It consists of a horizontal plate, a perpendicular plate, and two lateral labyrinths.
Rhinitis, Allergic, Perennial
Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.
Nasal Decongestants
Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)
Schizophyllum
A genus of fleshy shelf basidiomycetous fungi, family Schizophyllaceae, order POLYPORALES, growing on woody substrata. It is pathogenic in humans.
Otitis Media
Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
Brain Abscess
A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)
Epidural Abscess
Circumscribed collections of suppurative material occurring in the spinal or intracranial EPIDURAL SPACE. The majority of epidural abscesses occur in the spinal canal and are associated with OSTEOMYELITIS of a vertebral body; ANALGESIA, EPIDURAL; and other conditions. Clinical manifestations include local and radicular pain, weakness, sensory loss, URINARY INCONTINENCE, and FECAL INCONTINENCE. Cranial epidural abscesses are usually associated with OSTEOMYELITIS of a cranial bone, SINUSITIS, or OTITIS MEDIA. (From Adams et al., Principles of Neurology, 6th ed, p710 and pp1240-1; J Neurol Neurosurg Psychiatry 1998 Aug;65(2):209-12)
Trichosporonosis
Fungal infections caused by TRICHOSPORON that may become systemic especially in an IMMUNOCOMPROMISED HOST. Clinical manifestations range from superficial cutaneous infections to systemic lesions in multiple organs.
Stomatognathic Diseases
General or unspecified diseases of the stomatognathic system, comprising the mouth, teeth, jaws, and pharynx.
Empyema, Subdural
An intracranial or rarely intraspinal suppurative process invading the space between the inner surface of the DURA MATER and the outer surface of the ARACHNOID.
Common Cold
A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.
Paranasal Sinus Neoplasms
Tumors or cancer of the PARANASAL SINUSES.
Tonsillitis
Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.
Bacteria, Anaerobic
Rhizopus
A genus of zygomycetous fungi of the family Mucoraceae, order MUCORALES, a common saprophyte and facultative parasite of mature fruits and vegetables. It may cause cerebral mycoses in diabetes and cutaneous infection in severely burned patients.
Nasal Obstruction
Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.
Kartagener Syndrome
An autosomal recessive disorder characterized by a triad of DEXTROCARDIA; INFERTILITY; and SINUSITIS. The syndrome is caused by mutations of DYNEIN genes encoding motility proteins which are components of sperm tails, and CILIA in the respiratory and the reproductive tracts.
Nasal Septum
The partition separating the two NASAL CAVITIES in the midplane. It is formed by the SEPTAL NASAL CARTILAGE, parts of skull bones (ETHMOID BONE; VOMER), and membranous parts.
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
Cyclacillin
A cyclohexylamido analog of PENICILLANIC ACID.
Moraxella (Branhamella) catarrhalis
Gram-negative aerobic cocci of low virulence that colonize the nasopharynx and occasionally cause MENINGITIS; BACTEREMIA; EMPYEMA; PERICARDITIS; and PNEUMONIA.
Amoxicillin
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
Intubation, Gastrointestinal
The insertion of a tube into the stomach, intestines, or other portion of the gastrointestinal tract to allow for the passage of food products, etc.

Comparative in vitro activities of amoxicillin-clavulanate against aerobic and anaerobic bacteria isolated from antral puncture specimens from patients with sinusitis. (1/679)

By an agar dilution method, the antimicrobial susceptibilities of antral sinus puncture isolates were studied. Pneumococci were generally susceptible to amoxicillin, azithromycin, and clarithromycin, but 17% of pneumococcal isolates were resistant to cefuroxime. Haemophilus influenzae isolates were resistant to amoxicillin and clarithromycin. beta-Lactamase production occurred in 69% of Prevotella species. One-third of Peptostreptococcus magnus isolates were resistant to azithromycin and clarithromycin. Cefuroxime had limited activity against Prevotella species and P. magnus. Levofloxacin was active against most isolates except peptostreptococci. Amoxicillin-clavulanate was active against all isolates, with the MIC at which 90% of the isolates were inhibited being < or = 1 microgram/ml.  (+info)

Nasal nitric oxide concentration in paranasal sinus inflammatory diseases. (2/679)

In normal upper airways, nitric oxide is generated by the paranasal sinus epithelium and then diffuses into the nasal cavities. This study examined whether or not nasal NO concentration is affected by paranasal sinus inflammatory diseases. The influence of obstruction (nasal polyposis) and/or inflammation (allergy or chronic sinusitis) of the paranasal sinuses on nasal NO concentration was evaluated in nasal allergic (n=7 patients) or nonallergic (n=20) polyposis, nonallergic chronic sinusitis (n=10) and Kartagener's syndrome (n=6) and compared with control subjects (n=42). A score of alteration of the paranasal sinus (number of altered and occluded sinuses) was determined by a computed tomography scan. The nasal NO concentration in nasal nonallergic polyposis (150+/-20 parts per billion (ppb)) was significantly decreased compared with both controls (223+/-6 ppb, p=0.01) and polyposis with allergy (272+/-28 ppb, p<0.0001). In each group, the nasal NO concentration was inversely correlated with the extent of tomodensitometric alteration of the paranasal sinuses. In Kartagener's syndrome, the nasal NO concentration (14+/-2 ppb) was drastically decreased compared with all other groups, despite the presence of open paranasal sinuses. Thus, the nasal NO concentration in patients with nasal polyposis appeared to be dependent on both the allergic status and the degree of obstruction of the paranasal sinuses.  (+info)

IL-12 receptor beta2 and CD30 expression in paranasal sinus mucosa of patients with chronic sinusitis. (3/679)

The aetiology of chronic sinusitis is still poorly understood. The expression of T-helper 1 (Th1) and T-helper 2 (Th2) cell markers, interleukin (IL)-12 receptor beta2 subunit (IL-12Rbeta2) messenger ribonucleic acid (mRNA) and CD30, respectively, were investigated in the paranasal sinus mucosa of patients with chronic sinusitis in an attempt to elucidate the involvement of Th1 and Th2 cells in this disease. Anterior ethmoidal mucosae were surgically obtained from two groups of patients with chronic sinusitis: those who had allergic rhinitis (allergic group, n=11) and those without allergy (nonallergic group, n=11). IL-12Rbeta2 mRNA was quantified by means of the reverse transcription polymerase chain reaction, and CD30-positive cells were examined immunohistochemically. Both IL-12Rbeta2 mRNA and CD30 were expressed in the sinus mucosa of the allergic and nonallergic groups. The proportion of mononuclear cells which were CD30-positive in the sinus mucosa was significantly greater in the allergic than in the nonallergic group. The expression levels of IL-12Rbeta2 mRNA were virtually equivalent in both groups. These results suggest a T-helper 2-dominated mucosal reaction in the allergic compared to the nonallergic group, and indicate T-helper 1 activity in the sinus mucosa of both groups. The ubiquity of T-helper 1 cells suggests that they play a role in maintaining local mucosal defences against foreign antigens, which continually enter the upper respiratory tract.  (+info)

A possible mechanism of primary ciliary dyskinesia: a case of a segmental defect in ciliary microtubules. (4/679)

We report here a 13-year-old woman with cough, sputum and fever. The patient had both chronic sinusitis and bronchitis. Chest X-ray and computed tomographic scan of the chest revealed mucous bronchial filling and bronchiectasia in bronchi of bilateral lower lobes, right middle lobe and left upper lobe. Aerosol inhalation scintigraphy with 99mTechnetium demonstrated delays of the discharged tracer. On the basis of these findings, primary ciliary dyskinesia was suggested. This was confirmed by the findings from nasal biopsy with transmission electron microscopy where all of the microtubules were segmentally defected near the basal body in the cilia. On the basis of these findings, we diagnosed the patient with primary ciliary dyskinesia which may be due, at least in part, to segmental defect of ciliary microtubules.  (+info)

A locus for primary ciliary dyskinesia maps to chromosome 19q. (5/679)

Primary ciliary dyskinesia is an autosomal recessive condition characterised by chronic sinusitis, bronchiectasis, and subfertility. Situs inversus occurs in 50% of cases (Kartagener syndrome). It has an estimated incidence of 1 in 20 000 live births. The clinical phenotype is caused by defective ciliary function associated with a range of ultrastructural abnormalities including absent dynein arms, absent radial spokes, and disturbed ciliary orientation. The molecular genetic basis is unknown. A genome scan was performed in five Arabic families. Using GENEHUNTER, a maximal multipoint lod score (HLOD) of 4.4 was obtained on chromosome 19q13.3-qter at alpha (proportion of linked families) = 0.7. A 15 cM critical region is defined by recombinations at D19S572 and D19S218. These data provide significant evidence for a PCD locus on chromosome 19q and confirm locus heterogeneity.  (+info)

Invasive aspergillosis in a patient with MELAS syndrome. (6/679)

Invasive infection with the opportunistic fungus Aspergillus fumigatus predominantly affects people with impaired cell mediated immunity. The case of a 31 year old woman with no identified cause for immunosuppression who presented with severe refractory aspergillosis of the paranasal sinuses is reported. She subsequently developed clinical and molecular evidence of mitochondrial encephalomyopathy with lactic acidosis and stroke-like events (MELAS) syndrome. It is proposed that MELAS syndrome may represent an unusual risk factor for the development of invasive aspergillosis and mechanisms are supported by which mitochondrial dysfunction may predispose to this.  (+info)

The role of cytokines in rhinosinusitis. (7/679)

Since the last decade, new insights into inflammatory processes have become possible by investigating the pattern of cytokines in acute and chronic sinus diseases. This review aims to update and discuss the findings of in vitro and in vivo studies concerning the role of cytokines in sinusitis and nasal polyposis. The proinflammatory cytokines interleukin-1beta, interleukin-6 and the neutrophil-chemoattractant interleukin-8 may play a major role in acute sinusitis, as shown in viral and allergic rhinitis. In chronic sinusitis interleukin-3 dominates the cytokine profiles, giving support to a variety of inflammatory cells. Interleukin-5 is a key protein in the pathogenesis of nasal polyposis. Activation and survival of eosinophils in nasal polyps are thought to be regulated by interleukin-5. Further investigation of cytokine expression patterns in inflammatory sinus diseases will lead to a better understanding of their pathogenesis and to a development of new therapeutic modality.  (+info)

Report of successful prolonged antifungal therapy for refractory allergic fungal sinusitis. (8/679)

Allergic fungal sinusitis (AFS) is an increasingly recognized cause of refractory chronic sinusitis in the young immunocompetent host, analogous to allergic bronchopulmonary aspergillosis (ABPA), a related process in the lower respiratory tract. Most patients experience remittent disease despite corticosteroid therapy and aggressive sinus surgery. Because controlled trials have shown adjunctive antifungal therapy to be of benefit in treating ABPA, long-term oral itraconazole was used in a young man with remittent AFS, which was able to break the cycle of relapsing disease.  (+info)

Acute Bacterial Rhinosinusitis in Adults: Part I. Evaluation - American Family PhysicianAcute Bacterial Rhinosinusitis in Adults: Part I. Evaluation - American Family Physician
Acute rhinosinusitis is one of the most common conditions that physicians treat in ambulatory practice. Although often caused by viruses, it sometimes is caused by bacteria, a condition that is called acute bacterial rhinosinusitis. The signs and symptoms of acute bacterial rhinosinusitis and prolonged viral upper respiratory infection are similar, which makes accurate clinical diagnosis difficult. Because two thirds of patients with acute bacterial rhinosinusitis improve without antibiotic treatment and most patients with viral upper respiratory infection improve within seven d antibiotic therapy should be reserved for use in patients who have had symptoms for more than seven days and meet clinical criteria. Four signs and symptoms are the most helpful in predicting acute bacterial rhinosinusitis: purulent nasal discharge, maxillary tooth or facial pain (especially unilateral), unilateral maxillary sinus tenderness, and worsening symptoms after initial improvement. Sinus radiography and ultrasonography
http://www.aafp.org/afp/2004/1101/p1685.html
Rocklin Unified School District - Sinus Infection (Sinusitis)Rocklin Unified School District - Sinus Infection (Sinusitis)
Sinusitis, or a sinus infection, occurs when the sinuses and nasal passages become inflamed. If you or your child is diagnosed with sinusitis, the infection does not need to be treated with antibiotics unless you or your child has acute bacterial sinusitis, which is caused by bacteria. Acute bacterial sinusitis can last up to 4 weeks and subacute bacterial sinusitis can last 4 to 12 weeks, occurring less than 4 times per year.. Acute viral sinusitis, caused by a virus, typically lasts for less than 4 weeks and occurs less than 3 times per year. Acute viral sinusitis usually occurs after having an upper respiratory infection.. Chronic sinusitis typically lasts more than 4 weeks and occurs more than 4 times per year. If you are diagnosed with chronic sinusitis, you should visit a specialist for evaluation. Chronic sinusitis can be caused by nasal polyps or tumors, allergies, or respiratory tract infections (viral, bacterial, or fungal), among other reasons.. ...
http://www.rocklinusd.org/Departments/Health-Services/Common-Conditions/Sinus-Infection-Sinusitis/index.html
Sinusitis Bacterial - Chronic Sinus Infection Symptoms - Watch Out For Chronic Sinus Infection Symptoms
Treatment for chronic sinus infection symptoms Antibiotics and over-the-counter decongestants are widely used fro treating chronic sinus infection symptoms. Antibiotics may not be effective in chronic sinusitis because they target bacteria, not fungi. The antibiotic treatment usually takes 3 - 4 weeks. The over-the-counter medications may offer some relief from pain, but they do not have any effect on the inflammation. Clean and drain sinuses works in some cases. Oral pills may provide relief from stuffy nose and some nasal sprays can help in relieving chronic sinus infection symptoms caused by allergies. Patients of chronic sinus infection symptoms can find relief through Endoscopic Sinus Surgery (ESS). This is a noninvasive outpatient procedure. The study results suggest that ESS helps to reduce dependence on antibiotics and antihistamines for managing the symptoms. Deviated septum and nasal obstruction may be repaired surgically to prevent chronic sinus infection symptoms ...
http://sinustip.info/kqcz.aspx
Functional Endoscopic Sinus Surgery (FESS) | Sinusitis SurgeryFunctional Endoscopic Sinus Surgery (FESS) | Sinusitis Surgery
Your doctor has suggested you have functional endoscopic sinus surgery as part of your treatment. Functional endoscopic sinus surgery (FESS) has become the accepted standard approach and technique when surgical treatment of sinusitis is indicated.
https://www.nationaljewish.org/conditions/tests-procedures/adult-surgery-procedures/functional-endoscopic-sinus-surgery-fess
Prevention of Sinusitis Archives - SilvioumPrevention of Sinusitis Archives - Silvioum
Have you ever had an exceptionally severe or prolonged cold or allergy crisis? If so, there is a good chance that it was sinusitis. This number could be significantly higher since the symptoms of bacterial sinusitis often mimic those of a cold or allergy, and many patients never see a doctor for proper diagnosis and antibiotic treatment.. When acute sinusitis turns into chronic sinusitis. When you frequently suffer from sinusitis, and the infection lasts for three months or more, it could be chronic sinusitis whose symptoms may be less severe than those of acute sinusitis.. In chronic sinusitis, irreversible inflammatory changes may appear in the mucosa of the nose and perinasal sinuses, which may require surgery for repair.. Fungal allergies can also cause sinusitis. These pictures usually manifest as a predominantly chronic infection, rather than acute.. Prevention Of Sinusitis. As always, prevention is better than cure. To avoid sinusitis during a cold or allergic crisis, keep your sinuses ...
http://silvioum.com/category/prevention-of-sinusitis/
Clinical Practice Guideline for the Diagnosis and Management of Acute Bacterial Sinusitis in Children Aged 1 to 18 Years | From...Clinical Practice Guideline for the Diagnosis and Management of Acute Bacterial Sinusitis in Children Aged 1 to 18 Years | From...
The purpose of this key action statement is to guide the selection of antimicrobial therapy once the diagnosis of acute bacterial sinusitis has been made. The microbiology of acute bacterial sinusitis was determined nearly 30 years ago through direct maxillary sinus aspiration in children with compatible signs and symptoms. The major bacterial pathogens recovered at that time were Streptococcus pneumoniae in approximately 30% of children and nontypeable Haemophilus influenzae and Moraxella catarrhalis in approximately 20% each.16,40 Aspirates from the remaining 25% to 30% of children were sterile.. Maxillary sinus aspiration is rarely performed at the present time unless the course of the infection is unusually prolonged or severe. Although some authorities have recommended obtaining cultures from the middle meatus to determine the cause of a maxillary sinus infection, there are no data in children with acute bacterial sinusitis that have compared such cultures with cultures of a maxillary sinus ...
http://pediatrics.aappublications.org/content/132/1/e262.full
Chronic Rhinosinusitis Market 2020 Size, Share, Research Methodology, Revenue By 2027 - Juneau News UpdatesChronic Rhinosinusitis Market 2020 Size, Share, Research Methodology, Revenue By 2027 - Juneau News Updates
The global Chronic Rhinosinusitis Market was valued at USD 2132.5 million in 2019 and is expected to reach USD 3508.0 million by 2027, at a CAGR of 7.4%, According to the current analysis of Emergen Research. Development and manufacture of proficient sinusitis drugs are likely to be highly demanded for efficient treatment of chronic rhinosinusitis as, pollutants, fungal infections and allergies immensely contribute to the rising incidence of rhinosinusitis. Moreover, growing prevalence of growing prevalence of chronic asthma, inflammation of mucosal linings of the nasal passage, and cases of paranasal sinuses are expected to fuel the growth prospects of chronic rhinosinusitis market in the forecast period. Request a sample copy of the report @ https://www.emergenresearch.com/request-sample/74. Key Highlights From The Report. ...
http://news.juneaunewsupdates.com/story/310343/chronic-rhinosinusitis-market-2020-size-share-research-methodology-revenue-by-2027.html
Chronic Rhinosinusitis Market 2020 Size, Share, Research Methodology, Revenue By 2027 - Central India ChronicleChronic Rhinosinusitis Market 2020 Size, Share, Research Methodology, Revenue By 2027 - Central India Chronicle
The global Chronic Rhinosinusitis Market was valued at USD 2132.5 million in 2019 and is expected to reach USD 3508.0 million by 2027, at a CAGR of 7.4%, According to the current analysis of Emergen Research. Development and manufacture of proficient sinusitis drugs are likely to be highly demanded for efficient treatment of chronic rhinosinusitis as, pollutants, fungal infections and allergies immensely contribute to the rising incidence of rhinosinusitis. Moreover, growing prevalence of growing prevalence of chronic asthma, inflammation of mucosal linings of the nasal passage, and cases of paranasal sinuses are expected to fuel the growth prospects of chronic rhinosinusitis market in the forecast period. Request a sample copy of the report @ https://www.emergenresearch.com/request-sample/74. Key Highlights From The Report. ...
http://www.centralindiachronicle.com/story/90238/chronic-rhinosinusitis-market-2020-size-share-research-methodology-revenue-by-2027.html
Sinusitis Specialists In Miami - Chronic Sinus Infection Symptoms - Watch Out For Chronic Sinus Infection Symptoms
Although having acute sinusitis always causes discomfort, the condition usually does not take long for it to clear up. It is believed that the body immune system is strong enough to fight the infection on its own and only requires a few days for it to clear this condition. However, if the infection takes longer for it to come to an end, seeking a doctors advice is always the best option. During diagnosis, the doctor is usually able to distinguish between the various causes of acute sinusitis by mixing the patients rhinosinusitis (watery fluids that usually drains out of the nose when one has acute sinusitis) with a Gram stain. For viral acute sinusitis, the bacteria present in the nasal fluid are often seen in association with several clusters of epithelial cells while in bacterial acute sinusitis, the bacteria will be seen admixed with polymophonuclear leocucytes. After determining this, the doctor will be in a better position to prescribe a proper course of treatment that could end this ...
http://sinusitisrelief.info/kcjv.aspx
Biomolecules | Free Full-Text | Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma |...Biomolecules | Free Full-Text | Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma |...
Eosinophilic chronic rhinosinusitis (ECRS), a subgroup of chronic rhinosinusitis with nasal polyps, is recognized as a refractory eosinophilic disorder characterized by both upper and lower airway inflammation. In some severe cases, disease control is poor, likely due to local steroid insensitivity. In this study, we focused on protein phosphatase 2A (PP2A), a key factor regulating glucocorticoid receptor (GR) nuclear translocation, and examined its association with local responses to corticosteroids in eosinophilic airway inflammation. Our results indicated reduced responses to corticosteroids in nasal epithelial cells from ECRS patients with asthma, which were also associated with decreased PP2A mRNA expression. Eosinophil peroxidase stimulates elevated PP2A phosphorylation levels, reducing PP2A protein expression and activity. In addition, mRNA levels of inflammatory mediators (TSLP, IL-25, IL-33, CCL4, CCL5, CCL11, and CCL26) associated with eosinophilic airway inflammation in epithelial cells were
https://www.mdpi.com/2218-273X/10/2/326/htm
MUC8 mucin gene up-regulation in chronic rhinosinusitis<...
TY - JOUR. T1 - MUC8 mucin gene up-regulation in chronic rhinosinusitis. AU - Lee, Heung Man. AU - Kim, Dae Hoon. AU - Lee, Sang Hag. AU - Kim, Jung Min. AU - Hwang, Soon Jae. PY - 2004/8/1. Y1 - 2004/8/1. N2 - The primary mechanisms leading to mucus hypersecretion in chronic sinus inflammation are not well understood. This study aims to investigate the expression of MUC8 messenger RNA (mRNA) and protein and to compare between normal and chronically inflamed sinus mucosae in terms of the expression of MUC8 mRNA. Ten patients with chronic rhinosinusitis who were undergoing functional endoscopic sinus surgery were recruited for the study. Ten patients with no evidence of sinus disease were used as control subjects. RNAs were extracted from sinus mucosa, and semiquantitative reverse transcription-polymerase chain reaction was performed for MUC8. Localization of MUC8 protein was sought by immunohistochemical analysis. Messenger RNA encoding MUC8 was detected in human sinus mucosa. The level of MUC8 ...
https://koreauniv.pure.elsevier.com/en/publications/muc8-mucin-gene-up-regulation-in-chronic-rhinosinusitis
Systemic and topical antibiotics for chronic rhinosinusitis | CochraneSystemic and topical antibiotics for chronic rhinosinusitis | Cochrane
Review question We reviewed the evidence for the benefits and harms of systemic (given by mouth) or topical (given by nose) antibiotics for people with chronic rhinosinusitis.. Background Chronic rhinosinusitis is a common condition that is defined as inflammation of the nose and paranasal sinuses (a group of air-filled spaces behind the nose, eyes and cheeks). Patients experience at least two or more of the following symptoms for at least 12 weeks: blocked nose, discharge from their nose or runny nose, pain or pressure in their face and/or a reduced sense of smell (hyposmia). Some people will also have nasal polyps, which are grape-like swellings of the normal nasal lining inside the nasal passage and sinuses.. Study characteristics We included five randomised controlled trials (RCTs) with a total of 293 participants. The studies were small (43 to 79 participants). Four recruited adults and the fifth children. Three studies only included people with chronic rhinosinusitis without nasal polyps, ...
http://www.cochrane.org/CD011994/ENT_systemic-and-topical-antibiotics-chronic-rhinosinusitis
The sinuses : Otolaryngology and Head and Neck Surgery - oi
Anatomy of the paranasal sinuses - Rhinosinusitis: an overview - Acute rhinosinusitis - Maxillary sinus lavage - Chronic rhinosinusitis - Nasal polyps - Antrochoanal polyps - Fungal sinusitis 1 - Fungal sinusitis 2: treatment - Complications of sinusitis 1 - Complications of sinusitis 2 - Complications of sinusitis 3 - Intracranial complications - Mucocoeles and pyocoeles - Secondary effects of suppurative sinusitis - Functional endoscopic sinus surgery (FESS) - Endoscopic approach to the frontal sinus - Complications of functional endoscopic sinus surgery - Endoscopic dacrocystorhinostomy (DCR) - Frontal sinus trephine - External fronto-ethmoidectomy - CSF rhinorrhoea - Sinonasal malignancy - Lateral rhinotomy with medial maxillectomy - Total maxillectomy - Craniofacial resection ...
http://oxfordindex.oup.com/view/10.1093/med/9780199230228.003.0240
Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis - Full Text View - ClinicalTrials.govSubcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis - Full Text View - ClinicalTrials.gov
Title of study: Subcutaneous Xolair (omalizumab) for treatment of chronic rhinosinusitis with nasal polyposis (CRS/NP). Objectives: To compare the efficacy of subcutaneous Xolair (omalizumab) to placebo in treatment of CRS/NP in terms of: (a) the effect on polypoid mucosal thickening in the anterior ethmoid and maxillary sinuses as measured on sinus CT scan, (b) the effect on volume of polypoid mucosal tissue in the nose and sinuses on rhinoscopic examination, and (c) the effect on CRS symptoms as measured by total symptom score.. Study Rationale: Chronic rhinosinusitis (CRS) is a persistent inflammatory condition with periodic flares, affecting 14% of the United States population with an estimated annual health care expenditure of $3.4 billion. CRS patients with nasal polyposis (NP) are the most difficult to treat and the most likely to undergo sinus surgery. Tissue eosinophilia is the hallmark feature and is associated with specific IgE to inhalants, elevated total serum immunoglobulin E ...
https://clinicaltrials.gov/ct2/show/NCT01066104?recr=Open&cond=%22Nose+Diseases%22&rank=11
Acute Sinusitis | Annals of Internal Medicine | American College of PhysiciansAcute Sinusitis | Annals of Internal Medicine | American College of Physicians
Acute sinusitis affects millions of persons in the United States every year and is among the most common reasons for physician visits, prompting over 3 million visits annually (1). The more accurate term for this condition is acute rhinosinusitis, because symptoms involve both the nasal cavity and the sinuses. For simplicity, this review uses the term sinusitis for rhinosinusitis. There are 4 pairs of air-filled paranasal sinuses: the frontal, maxillary, ethmoid, and sphenoid sinuses. Acute sinusitis typically occurs in the maxillary sinuses (Figure). Sinusitis is characterized as acute when the duration of symptoms is shorter than 4 weeks, subacute when the duration is from 4 weeks to 12 weeks, and chronic when the duration is more than 12 weeks. Sinusitis seems to be due to congestion and blockage of the nasal passages, usually in response to viral infection or allergic rhinitis but occasionally to other stimuli. The paranasal sinuses become inflamed, and mucus cannot drain properly, ...
http://annals.org/aim/article-abstract/746052/acute-sinusitis
Sinus surgery and delivery method influence the effectiveness of topical corticosteroids for chronic rhinosinusitis: Systematic...Sinus surgery and delivery method influence the effectiveness of topical corticosteroids for chronic rhinosinusitis: Systematic...
TY - JOUR. T1 - Sinus surgery and delivery method influence the effectiveness of topical corticosteroids for chronic rhinosinusitis. T2 - Systematic review and meta-analysis. AU - Snidvongs, Kornkiat. AU - Kalish, Larry. AU - Sacks, Raymond. AU - Sivasubramaniam, Rahuram. AU - Cope, Daron. AU - Harvey, Richard J.. PY - 2013/5. Y1 - 2013/5. N2 - Background: Published randomized controlled trials (RCTs) on the efficacy of intranasal corticosteroid (INCS) in chronic rhinosinusitis (CRS) use either nasal delivery (nasal drop or nasal spray) or sinus delivery (sinus catheter or sinus irrigation) in patients with or without sinus surgery. This influences topical drug delivery and distribution. The effect of these factors on the published results of RCTs is assessed. This systematic review explores the strength of evidence supporting the influence of sinus surgery and delivery methods on the effectiveness of topical steroids in studies for CRS with meta-analyses. Methods: A systematic review was ...
https://researchers.mq.edu.au/en/publications/sinus-surgery-and-delivery-method-influence-the-effectiveness-of-
dreddyclinic.com - Chronic sinusitis
What is Sinusitis, Chronic - Chronic sinusitis is one of the more prevalent chronic illnesses in the United States, affecting persons of all age groups. Generally defined as a sinus infection persisting for more than 3 months, this condition usually manifests differently than acute sinusitis. Symptoms of chronic sinusitis include nasal stuffiness, postnasal drip, facial fullness, and malaise. Most cases are continuations of unresolved acute sinusitis. Allergic and nonallergic rhinitis, anatomic obstruction in the osteomeatal complex, and immunologic disorders are known risk ...
http://www.dreddyclinic.com/findinformation/ss/chronicsinusitis.php
Steroids for acute sinusitis | Read by QxMDSteroids for acute sinusitis | Read by QxMD
BACKGROUND: Acute sinusitis is a common reason for primary care visits. It causes significant symptoms and often results in time off work and school.. OBJECTIVES: We examined whether intranasal corticosteroids (INCS) are effective in relieving symptoms of acute sinusitis.. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 4, 2006), MEDLINE (January 1966 to December 2006), EMBASE (1990 to June 2006) and bibliographies of included studies.. SELECTION CRITERIA: Randomized controlled trials (RCTs) were considered eligible if they compared INCS treatment to placebo treatment of a control group for acute sinusitis; acute sinusitis was defined by clinical diagnosis and confirmed by radiological evidence or by nasal endoscopy. The primary outcome was the proportion of participants with either resolution or improvement of symptoms. Secondary outcomes were any adverse events that required discontinuation of treatment, drop-outs before the end of ...
https://read.qxmd.com/read/17443574/steroids-for-acute-sinusitis
Evolution of amoxicillin/clavulanate in the treatment of adults with acute bacterial rhinosinusitis and community-acquired...
Current treatment guidelines for community-acquired respiratory tract infections no longer depend solely on the characteristics of the patient and the clinical syndrome, but on those of the offending pathogen, including presence and level of antimicrobial resistance. The most common respiratory tract pathogens known to cause acute bacterial rhinosinusitis (ABRS) and community-acquired pneumonia (CAP) include Streptococcus pneumoniae and Haemophilus influenzae. The prevalence of antimicrobial resistance, especially b-lactum and macrolide resistance, among S pneumoniae and H influenzae has increased dramatically during the past 2 decades, diminishing the activity of many older antimicrobials against resistant organisms. A pharmacokinetically enhanced formulation of amoxicillin/clavulanate has been developed to fulfill the need for an oral b-lactam antimicrobial that achieves a greater time that the serum drug concentration exceeds the minimum inhibitory concentration (T \textgreater MIC) of ...
https://neomed.omeka.net/items/show/3530
Acute Bacterial Rhinosinusitis (ABRS) - Gundersen Health System - La Crosse, Wisconsin
Acute bacterial rhinosinusitis (ABRS) is an infection of your nasal cavity and sinuses. Its caused by bacteria. Acute means that youve had symptoms for less than 12 weeks.
http://healthinfo.gundersenhealth.org/Library/DiseasesConditions/Pediatric/Pregnancy/3,90261
Acute Bacterial Rhinosinusitis (ABRS)Acute Bacterial Rhinosinusitis (ABRS)
Acute bacterial rhinosinusitis (ABRS) is an infection of your nasal cavity and sinuses. Its caused by bacteria. Acute means that youve had symptoms for less than 12 weeks.
http://library.oumedicine.com/Library/DiseasesConditions/Pediatric/Allergy/3,90261
Low-stage computed tomography chronic rhinosinusitis: What is the role of endoscopic sinus surgery? - Rudmik - 2011 - The...Low-stage computed tomography chronic rhinosinusitis: What is the role of endoscopic sinus surgery? - Rudmik - 2011 - The...
A total of 778 patients with CRS were enrolled between January 2001 and April 2009 after electing ESS. For the purposes of this analysis, patients with nasal polyposis, history of prior sinus surgery, or follow-up ,6 months were excluded. Final study patients were categorized as low-stage CT CRS (Lund-Mackay ≤3; n = 17) and high-stage CT CRS (Lund-Mackay ,3; n = 207). Primary outcome measures included two disease-specific QoL instruments: the Rhinosinusitis Disability Index and the Chronic Sinusitis Survey. ...
http://onlinelibrary.wiley.com/doi/10.1002/lary.21382/abstract
Sinusitis | University of Maryland Medical CenterSinusitis | University of Maryland Medical Center
Sinusitis. Sinusitis is an inflammation or infection of the sinuses, the air-filled chambers in the skull that are located around the nose. Symptoms of sinusitis include thick nasal discharge, facial pain or pressure, fever, and reduced sense of smell. Depending on how long these symptoms last, sinusitis is classified as acute, subacute, chronic, or recurrent. Viruses are the most common cause of acute sinusitis, but bacteria are responsible for most of the serious cases.. Non-Drug Treatment of Sinusitis. Home remedies such as saline (salt) washes or sprays are helpful for removing mucus and relieving congestion. Steam inhalation is also beneficial. Patients with sinusitis should drink plenty of fluids to avoid dehydration. Water, which helps lubricate the mucous membranes, is the best fluid to drink.. Drug Treatment of Sinusitis. Medication depends on the type of sinusitis and its cause. Non-prescription pain relievers such as acetaminophen and ibuprofen can help mild-to-moderate pain symptoms. ...
http://www.umm.edu/health/medical/reports/articles/sinusitis
Sniffing out the problemSniffing out the problem
Sniffing out the problem Jonathan Hern Commissioning Guide for Chronic Rhinosinusitis • ENTUK and RCS • Based on European position paper on sinusitis • Guidance for primary and secondary care treatment of sinusitis Introduction • • • • • • Acute sinusitis Duration , 12 weeks Aetiology usually infective Chronic sinusitis Duration , 12 weeks Aetiology multifactorial including inflammatory, infective and obstructive (sinus ventilation and drainage) • 10% prevalence in UK Acute sinusitis • History • Presence of 2 or more symptoms for , 12 weeks • Either nasal obstruction and/or discharge • Facial pain/pressure • Reduced sense of smell Acute sinusitis Acute sinusitis Paediatric acute sinusitis Chronic Sinusitis in primary care • • • • • • History Presence of 2 or more symptoms for , 12 weeks Either nasal obstruction and/or discharge Facial pain/pressure Reduced sense of smell Subcategorised by presence or absence of nasal polyps • CRSwNP or CRSsNP • ...
http://slidegur.com/doc/176277/sniffing-out-the-problem
Sinusitis | Middleburg Hts, OH | Pediatric & Adolescent Health ProfessionalsSinusitis | Middleburg Hts, OH | Pediatric & Adolescent Health Professionals
Acute sinusitis can show up with either persistent (the most common form) or severe symptoms. Patients with persistent symptoms of acute sinusitis are differentiated from patients with simple colds solely on the basis of the duration of the symptoms. A simple cold usually lasts 5 to 7 days, and, even if symptoms linger, there should be improvement by 10 days. Cold symptoms that show no improvement after 10 days may be acute bacterial sinusitis.. The symptoms of cold viruses are indistinguishable from acute bacterial sinusitis. They usually include either nasal discharge (thin or thick; white, yellow, or green) or a cough (dry or wet) during both the day and the night. Some children also have bad breath, and/or swelling and darkening around the eyes. Complaints of a headache and facial pain are unusual until adolescence.. The second, less common appearance of acute sinusitis is a cold that seems more severe than usual. The severity is defined by the combination of a high fever (higher than ...
http://pediatricadolescenthealthprofessionals.rainbowbabies.org/Parent-Resources/Medical-Conditions/Sinusitis.aspx
Sinusitis | Lorain, OH | University Pediatrics of LorainSinusitis | Lorain, OH | University Pediatrics of Lorain
Acute sinusitis can show up with either persistent (the most common form) or severe symptoms. Patients with persistent symptoms of acute sinusitis are differentiated from patients with simple colds solely on the basis of the duration of the symptoms. A simple cold usually lasts 5 to 7 days, and, even if symptoms linger, there should be improvement by 10 days. Cold symptoms that show no improvement after 10 days may be acute bacterial sinusitis.. The symptoms of cold viruses are indistinguishable from acute bacterial sinusitis. They usually include either nasal discharge (thin or thick; white, yellow, or green) or a cough (dry or wet) during both the day and the night. Some children also have bad breath, and/or swelling and darkening around the eyes. Complaints of a headache and facial pain are unusual until adolescence.. The second, less common appearance of acute sinusitis is a cold that seems more severe than usual. The severity is defined by the combination of a high fever (higher than ...
http://universitypediatricsoflorain.rainbowbabies.org/Parent-Resources/Medical-Conditions/Sinusitis.aspx
Sinusitis | Bainbridge, Broadview, Garfield & Mayfield Hts, Twinsburg, OH | Pediatricenter
Acute sinusitis can show up with either persistent (the most common form) or severe symptoms. Patients with persistent symptoms of acute sinusitis are differentiated from patients with simple colds solely on the basis of the duration of the symptoms. A simple cold usually lasts 5 to 7 days, and, even if symptoms linger, there should be improvement by 10 days. Cold symptoms that show no improvement after 10 days may be acute bacterial sinusitis.. The symptoms of cold viruses are indistinguishable from acute bacterial sinusitis. They usually include either nasal discharge (thin or thick; white, yellow, or green) or a cough (dry or wet) during both the day and the night. Some children also have bad breath, and/or swelling and darkening around the eyes. Complaints of a headache and facial pain are unusual until adolescence.. The second, less common appearance of acute sinusitis is a cold that seems more severe than usual. The severity is defined by the combination of a high fever (higher than ...
http://pediatricenter.rainbowbabies.org/Parent-Resources/Medical-Conditions/Sinusitis.aspx
IL-19 Promotes Nasal Mucosal Tissue Remodeling in Chronic Rhinosinusitis Patients By Upregulating Fibronectin and Collagen Ι...IL-19 Promotes Nasal Mucosal Tissue Remodeling in Chronic Rhinosinusitis Patients By Upregulating Fibronectin and Collagen Ι...
BackgroundChronic sinusitis without nasal polyps (CRSsNP), a subtype of chronic rhinosinusitis, is characterized by tissue remodeling, mainly by interstitial fibrosis. Fibroblasts are essential effectors of tissue remodeling, mainly expressing fibronectin (FN), collagen...
https://www.researchsquare.com/article/rs-165739/v1
chronic sinus - Symptoms, Treatments and Resources for chronic sinuschronic sinus - Symptoms, Treatments and Resources for chronic sinus
chronic sinus - MedHelps chronic sinus Center for Information, Symptoms, Resources, Treatments and Tools for chronic sinus. Find chronic sinus information, treatments for chronic sinus and chronic sinus symptoms.
https://www.medhelp.org/tags/show/50305/chronic-sinus
Chronic sinusitis and GERD or extraesophageal reflux disease - acid reflux
Chronic sinusitis and GERD. chronic sinusitis is a common clinical condition. There is increasing evidence from observational studies that both paediatric and adult patients with chronic sinusitis frequently have associated GORD and EOR and that these patients may benefit from medical antireflux therapy. GORD and EOR may contribute to the pathogenesis of chronic sinusitis by causing sinonasal congestion, compromised sinus drainage, and inflammation.29 Otitis media Otitis media with effusion (OME) is a prevalent condition and the most common cause of hearing loss in childhood. Recently, Tasker et al reported high concentrations (up to a 1000-fold greater than serum levels) of pepsin/pepsinogen in 59 of 65 middle ear effusion samples from children with OME. The authors concluded that reflux of gastric juice into the middle ear may be the primary factor in the initiation of OME in children. Using upper gastrointestinal endoscopy and 24 hour pH monitoring, we prospectively assessed the coexistence ...
http://acidrefluxmed247.com/chronic-sinusitis-gerd-extraesophageal-reflux-disease/
Acute Sinusitis Homeopathy - Know the Symptoms of a Sinus Infection in an Instant
Take a look at these simple guidelines to help you differentiate a sinusitis from a common cold: 1. Duration of the condition Monitoring how long a common cold lasts is the most perceptible way to differentiate it from a sinusitis. The duration of a common cold actually varies but it usually lasts for not more than 10 days. On the other hand, a sinus infection lasts for approximately 10 to 14 days or more. Specifically, the symptoms of an acute sinusitis last for less than 4 weeks while those of a chronic sinusitis last for more than 8 weeks. In case the sinusitis recurs for about 3 or more acute episodes in a year, it is also classified as chronic ...
http://sinustip.info/kmgm.aspx
Health utility outcomes in patients undergoing medical management for chronic rhinosinusitis: A prospective multiinstitutional...Health utility outcomes in patients undergoing medical management for chronic rhinosinusitis: A prospective multiinstitutional...
TY - JOUR. T1 - Health utility outcomes in patients undergoing medical management for chronic rhinosinusitis. T2 - A prospective multiinstitutional study. AU - Luk, Lauren J.. AU - Steele, Toby. AU - Mace, Jess C.. AU - Soler, Zachary M.. AU - Rudmik, Luke. AU - Smith, Timothy. PY - 2015/11/1. Y1 - 2015/11/1. N2 - Background: A health utility value represents an individuals preference for living in a specific health state and is used in cost-utility analyses. This study investigates the impact of continuing medical therapy on health utility outcomes in patients with chronic rhinosinusitis (CRS). Methods: The Medical Outcomes Study Short Form-6D (SF-6D) questionnaire was administered to patients prospectively enrolled in a longitudinal study examining treatment outcomes for CRS. Patients were prescribed robust, initial medical therapy and then elected to continue with medical therapy (n = 40) or undergo endoscopic sinus surgery (ESS), followed by medical therapy (n = 152). Patients observed ...
https://ohsu.pure.elsevier.com/en/publications/health-utility-outcomes-in-patients-undergoing-medical-management-2
Clear Inflamed Sinuses - How To Avoid And Cure Sinus Infections And A Sinusitis Cough
If a person are suffering from a bad cough and your favorite cold medicine treatment does not seem to work at all, next what you are suffering from might be a sinusitis house remedies is due to sinusitis.. Simple sinus inflammation shouldnt be taken as a given as this usually comes with contamination. There are actually two basic kinds of sinus bacterial infections, acute and also chronic sinusitis.. Avoid exposure to chemicals, smoke and other toxic irritants -Avoiding flights -Avoid boating in chlorinated pools for years -Moisturizing the nose together with saline sprays -Avoid water diving -Avoid meals that may cause allergic reactions. There are some way of life modifications that may be required as well, to treatment and prevent the occurrence of sinus infections and sinusitis cough, these might include:. Mold -House dirt -Pets -Mites -Cockroaches Most experts believe that an infection is not the principal cause of chronic sinusitis fever. However frequent attacks of acute sinusitis may ...
http://glassd.msgserver.net/Clear_Inflamed_Sinuses_How.html
Health Sinusitis - Sinus Infection and Dizziness Symptoms
To better understand why a sinus infection can take place, one must know what are the causes. Sinuses are the small, empty holes in your bony skull. These caverns are lined by mucus and make the connection to the nasal passages. Some people have them even at birth, whereas other grow in time, in the first twenty years of your life. Those small holes are affected by sinus infection. Sinusitis is the term that is given to a sinus infection. When those sinuses are infected, the sinuses are swollen, red and very tender. Mucus is also a characteristic of a sinus infection. If you take things technical, any cold can also be a case of a sinus infection, cause by a virus. However, when doctors diagnose you with a sinus infection like sinusitis they actually refer to an infection caused by a bacteria. There are three types of sinus infection that are caused by a bacteria. Acute, subacute and chronic sinus infection caused by a bacteria are the three types of sinus infection that have different causes and ...
http://sinus-pressure.info/kiah.aspx
Allergic Fungal Sinusitis Emedicine - Holistic Healing Practices With a Chiropractor
What are sinus infection symptoms? Most of the times sinus infection symptoms start with a blocked nose or runny nose, flu, cough, headache, sore throat, pain around the nasal area, loss of taste or smell etc. Usual symptoms also include swelling around the nose and blockage of the nasal channels. Pain in the cheek or face, greenish discharge can also be found in some cases. Normally sinus infection symptoms will go away within three weeks. If it persists longer, it is acute sinusitis. When this continues for more than three months, it is known as chronic sinusitis. Sinus infections are caused mostly by viruses, bacteria and fungus. Environmental pollution, allergens cause non-infectious sinusitis. Severe headache and painful red eyes and sometimes with double vision are known sinus infection symptoms. In acute case temporary vision loss is also possible. Fatigue, fever and loss of smell or taste are found in many other cases if the infection is caused by bacteria. Bacterial infections are cured ...
http://sinus-remedy.info/kacv.aspx
Comparison of Olfactory Function before and After Endoscopic Sinus SurgeryComparison of Olfactory Function before and After Endoscopic Sinus Surgery
Introduction: Olfactory loss in patients with chronic rhinosinusitis has been measured by different methods. However, the results have been variable, and it is not clear whether endoscopic sinus surgery significantly improves olfactory function. This study was performed to evaluate the influence of endoscopic sinus surgery on olfactory function in patients with chronic rhinosinusitis. Materials and Methods: In this prospective analytic study, 73 patients (mean age, 39.63±12.94 years) with a diagnosis of polyps and sinusitis during 2011 were studied. The olfaction test was performed with three solutions; one with no odor (water) and two with phenylethyl alcohol (50% and 90% dilution, respectively). The patients olfaction state were graded as no olfaction, or low, moderate or good olfaction before and 1 and 3 months after surgery, and was given scores between 0 and 3 and evaluated quantitatively. Results: Right-side olfaction was improved in 68.5% and left side in 67.1% of patients. Mean olfaction
http://ijorl.mums.ac.ir/article_10041_1308.html
Mapping and comparing bacterial microbiota in the sinonasal cavity of healthy, allergic rhinitis, and chronic rhinosinusitis...
TY - JOUR. T1 - Mapping and comparing bacterial microbiota in the sinonasal cavity of healthy, allergic rhinitis, and chronic rhinosinusitis subjects. AU - Lal, Devyani. AU - Keim, Paul. AU - Delisle, Josie. AU - Barker, Bridget. AU - Rank, Matthew A. AU - Chia, Nicholas D. AU - Schupp, James M.. AU - Gillece, John D.. AU - Cope, Emily K.. PY - 2017/6/1. Y1 - 2017/6/1. N2 - Background: The role of microbiota in sinonasal inflammation can be further understood by targeted sampling of healthy and diseased subjects. We compared the microbiota of the middle meatus (MM) and inferior meatus (IM) in healthy, allergic rhinitis (AR), and chronic rhinosinusitis (CRS) subjects to characterize intrasubject, intersubject, and intergroup differences. Methods: Subjects were recruited in the office, and characterized into healthy, AR, and CRS groups. Endoscopically-guided swab samples were obtained from the MM and IM bilaterally. Bacterial microbiota were characterized by sequencing the V3-V4 region of the 16S ...
https://mayoclinic.pure.elsevier.com/en/publications/mapping-and-comparing-bacterial-microbiota-in-the-sinonasal-cavit
The Role of Ubiquitous Airborne Fungi in Chronic Rhinosinusitis - Doug Kaufmanns Know the CauseThe Role of Ubiquitous Airborne Fungi in Chronic Rhinosinusitis - Doug Kaufmanns Know the Cause
Chronic rhinosinusitis (CRS) is a confusing disease for both allergists and otorhino- laryngologists, partly because of its poorly understood pathophysiology and partly because of its limited treatment options. Several recent reports have provided evidence for a better under- standing of the etiology and the relationship of CRS to airborne fungi-es…. Chronic rhinosinusitis (CRS) is a confusing disease for both allergists and otorhino- laryngologists, partly because of its poorly understood pathophysiology and partly because of its limited treatment options. Several recent reports have provided evidence for a better under- standing of the etiology and the relationship of CRS to airborne fungi-especially to Alternaria. First, the development of novel methods enables detection of certain fungi in mucus from the nasal and paranasal sinus cavities. Second, a non-IgE-mediated immunological mechanism for reactivity of patients with CRS to certain common fungi has been described. Third, these fungi ...
https://knowthecause.com/informational-article-2/
Chronic sinusitis patients experience improved quality of life after endoscopic sinus surgery | EurekAlert! Science NewsChronic sinusitis patients experience improved quality of life after endoscopic sinus surgery | EurekAlert! Science News
Upwards of 76 percent of patients with chronic rhinosinusitis experienced significant quality of life improvements after undergoing endoscopic sinus surgery, according to new research in the January 2010 issue of Otolaryngology -- Head and Neck Surgery.
https://www.eurekalert.org/pub_releases/2010-01/aaoo-csp122809.php
A Comparison of the Safety and Efficacy of Two Different Regimens of Levofloxacin in the Treatment of Acute Bacterial Sinusitis...A Comparison of the Safety and Efficacy of Two Different Regimens of Levofloxacin in the Treatment of Acute Bacterial Sinusitis...
When treating sinus infections (sinusitis) caused by bacteria, the traditional duration of therapy is between 10 and 14 days. In this randomized, double-blind study, 5 days of 750 milligrams of levofloxacin given once daily will be compared to 10 days of 500 milligrams of levofloxacin in the treatment of non-hospitalized adult patients who have acute bacterial sinusitis. To prevent the study doctor, study staff and patients from knowing which study drug they are taking, all study drug will manufactured to look the same and patients on the 5-day regimen will be given placebo for the last 5 days of their participation in the study. Patients will have a sinus specimen collected at the first visit. Safety evaluations will be conducted. The objective of the study is to demonstrate that, in the treatment of acute bacterial sinus infections, a 5-day course of 750 milligrams of levofloxacin given once daily is at least as effective as a 10-day course of 500 milligrams of levofloxacin given once daily ...
https://clinicaltrials.gov/ct2/show/NCT00236522?term=sinusitis&rank=3
Chronic Sinusitis - Humboldt Alumni Wine ClubChronic Sinusitis - Humboldt Alumni Wine Club
The symptoms of sinusitis, better known as sinus infection the symptoms, which occurs when a sinusitis - better known under the name sinus infection -, with different symptoms go hand in hand. Runny nose and nasal but usually include. But also headaches and in some cases, even dental pain may indicate a sinusitis. The acute sinus infection subsides generally within a few days back. This is not the case, a doctor should be consulted be sure as the sinusitis can be otherwise also chronic. This applies of course to avoid it, and a visit to the doctor too much is not enough this better than one. Only if clarifies, the form is the paranasal sinus inflammation and also, which it was born, a successful treatment can be initiate. At each acute sinusitis it comes first, accordingly to reduce the inflammation and fade away. A nasal spray can support work, but also means plant-based are used again and again. The severity of the nose side caves inflammation is decisive. The patient suffers from severe pain ...
http://www.humboldtalumniwineclub.com/chronic-sinusitis/
SinusitisSinusitis
The term sinusitis has now been officially replaced by rhinosinusitis in the Otolaryngology literature. Rhinosinusitis is divided into two main categories: acute (sinus infection lasting less than four weeks) and chronic (sinus infection lasting greater than twelve weeks). Sub-acute rhinosinusitis refers to a sinus infection lasting between four and twelve weeks.. Rhinosinusitis usually begins after obstruction of the sinus drainage pathways secondary to a viral URTI, or some other cause, resulting in stagnation of secretions within the sinus. Bacteria from the nasal cavity invade the mucus filled sinuses if the obstruction does not resolve within a few days. If the infection does not resolve within a few weeks, the mucus membrane will undergo polypoid change causing further obstruction. The flora will gradually change from one of acute sinusitis (S. pneumo, H.influenzae and Moraxella) to one of chronic sinusitis (anaerobes, gram negative enterococci). Once the infection has lasted greater ...
https://www.stpaulssinuscentre.com/learning/sinusitis/
Facts about Fungal Sinus Infections and How Long to Get Rid of Fungal Sinus Infection?Facts about Fungal Sinus Infections and How Long to Get Rid of Fungal Sinus Infection?
Fungal sinus infections occur when fungi in the air are inhaled and deposited in the paranasal sinuses and nasal passageways. There are four main types of fungal sinus infection; fungal ball, allergic fungal sinusitis, acute invasive fungal sinusitis and chronic invasive fungal sinusitis. Find out more about these as well as the answer to the question - how long does it take to get rid of a fungal sinus infection?
http://www.brighthub.com/science/genetics/articles/54490.aspx
Acute Rhinosinusitis - Letters to the Editor - American Family PhysicianAcute Rhinosinusitis - Letters to the Editor - American Family Physician
to the editor: Having just put together a lecture on acute rhinosinusitis, I eagerly opened the January 1, 2001 issue of American Family Physician to read Adult Rhinosinusitis: Diagnosis and Management.1 I was hoping to find validation of the conclusions I had drawn from my own weeks of study and synthesis on the subject. I also hoped to find new insights from an experienced author on the difficult issue of how we should approach patients with signs and symptoms that may be either viral or bacterial.. However, I was disappointed to find a review that relied heavily on the ear, nose, and throat and allergy literature and nearly ignored the research that has fueled multiple meta-analyses and new general practice studies of acute rhinosinusitis during the past few years.. To be specific, Dr. Osguthorpes discussion of the acute variety of rhinosinusitis fails to recognize studies that have reported which signs and symptoms have statistically significant correlations with bacterial infection and ...
https://www.aafp.org/afp/2002/0215/p558.html
New treatment for chronic sinusitis identifiedNew treatment for chronic sinusitis identified
A new treatment for chronic sinusitis has been identified by Summit Ear, Nose & Throat in an outpatient setting called FinESSâ„¢ Sinus Treatment.. FinESS can be classified as a new balloon sinuplasty technique, which is less invasive than the traditional sinus surgery. The technique breaks the cycle of chronic sinusitis with immediate relief to provide lasting results.. In this technique, a small balloon is inserted into the patients sinus passages. The balloon is inflated, deflated, and then removed.. This treatment option is considered by many members of the medical fraternity as a potential breakthrough for treating chronic sinusitis (CRS).. ...
https://www.isteroids.com/blog/new-treatment-for-chronic-sinusitis-identified/
Nasodren for Sinusitis Treatment: INFLAMMATION IN ACUTE (ARS) AND CHRONIC RHINOSINUSITIS (CRS)Nasodren for Sinusitis Treatment: INFLAMMATION IN ACUTE (ARS) AND CHRONIC RHINOSINUSITIS (CRS)
In ARS, it is common to find high IL-8 (which is the neutrophils main chemotactic agent), TNF-alpha and total protein levels. Neutrophil and T lymphocyte levels are also usually increased (both in the epithelium and in the lamina propria). There is more information available on the existence of inflammation in chronic rhinosinusitis (CRS) with nasal polyposis. Among other findings, there is one that is particularly interesting: the persistence of high eosinophil levels. Numerous inflammation mediators have been found in the sinonasal mucosa of subjects with CRS and nasal polyposis which may play an important role and may be caused both by specific substances and by other non-specific factors (cold, pollution,…). Glandular secretion is an important component of inflammation, manifesting as rhinorrhoea, and is regulated not only by inflammatory regulators but also by the epithelial and inflammatory cells themselves and by classic neurotransmitters. A landmark study performed by Roca Ferrer et ...
http://blog.nasodren.com/2013/04/inflammation-in-acute-ars-and-chronic.html
Sinusitis | Sonoran ENTA
Acute bacterial sinusitis is an infection of the sinus cavities caused by bacteria. It typically preceded by an upper respiratory infection/cold, allergy exacerbation, or by general environmental irritation. Typical treatment includes an antibiotic after appropriate diagnosis by an Otolaryngologist. With inflammation, the nose and sinuses become unable to drain appropriately. Symptoms can include purulent nasal drainage, nasal obstruction, and facial pain/pressure. The sinus infection is likely bacterial if infection lasts longer than 10 days. Chronic sinusitis occurs with symptoms and signs that persist longer than three months. Symptoms may be less severe than acute sinusitis.. Sinusitis Treatments:. ...
https://sonoranent.com/sinusitis/
Chronic SinusitisChronic Sinusitis
Patients who are found to have a chronic sinus issue may or may not be advised to try a surgical treatment soon after their consultation. Two of the most common sinus procedures that we offer for chronic sinusitis at our Seattle area practice are balloon sinuplasty and endoscopic sinus surgery.. A balloon sinuplasty may be the first intervention our ear, nose and throat doctors suggest since it does not involve any incisions or cutting of the nasal bones. During a balloon sinuplasty, Dr. Ummat uses a flexible balloon catheter to open up the nasal passages and sinuses in order to relieve the symptoms of chronic sinusitis. The balloon is inserted into the nasal passages while deflated and is then slowly inflated to allow mucus buildup to drain out of the sinuses. The system is flushed with saline to remove buildup and provide relief. While the results of this procedure may not be permanent, many patients experience long-term relief with little to no downtime.. Other patients may need surgery to ...
https://www.nwfacemedical.com/ear-nose-throat/chronic-sinusitus/
The One Probiotic That Treats Sinusitis - Lacto Bacto
UPDATED October 2018) Probiotics and sinusitis treatment go hand in hand. In the last few years researchers found that one probiotic (beneficial bacteria) that chronic sinusitis sufferers lack and that treats and cures sinusitis is Lactobacillus sakei. And for many, major improvement may take only days!. The researchers Abreu et al found in their 2012 study that not only do sinusitis sufferers lack L. sakei, they have too much of some other bacteria, and they also dont have the bacteria diversity in their sinuses that healthy people without sinusitis have. In other words, the sinus microbiome (microbial community) is out of whack (dysbiosis). A number of studies since then also found that there is a depletion of some bacterial species, and an increase in abundance of other species in those with chronic sinusitis.. Luckily Lactobacillus sakei is found in some foods (such as some brands of live fermented kimchi), some sausage starter cultures (such as B-2), and recently in some probiotic ...
https://lactobacto.com/2015/01/12/the-one-probiotic-that-cures-sinusitis/?replytocom=59212
The One Probiotic That Treats Sinusitis - Lacto Bacto
UPDATED October 2018) Probiotics and sinusitis treatment go hand in hand. In the last few years researchers found that one probiotic (beneficial bacteria) that chronic sinusitis sufferers lack and that treats and cures sinusitis is Lactobacillus sakei. And for many, major improvement may take only days!. The researchers Abreu et al found in their 2012 study that not only do sinusitis sufferers lack L. sakei, they have too much of some other bacteria, and they also dont have the bacteria diversity in their sinuses that healthy people without sinusitis have. In other words, the sinus microbiome (microbial community) is out of whack (dysbiosis). A number of studies since then also found that there is a depletion of some bacterial species, and an increase in abundance of other species in those with chronic sinusitis.. Luckily Lactobacillus sakei is found in some foods (such as some brands of live fermented kimchi), some sausage starter cultures (such as B-2), and recently in some probiotic ...
https://lactobacto.com/2015/01/12/the-one-probiotic-that-cures-sinusitis/?replytocom=51272

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