Protein Sorting Signals
Molecular Sequence Data
Amino Acid Sequence
Signal Processing, Computer-Assisted
Computer Communication Networks
Nuclear Localization Signals
Image Processing, Computer-Assisted
Reproducibility of Results
Neural Networks (Computer)
Recombinant Fusion Proteins
Medical Records Systems, Computerized
Sequence Homology, Amino Acid
Protein Structure, Tertiary
Adaptor Proteins, Signal Transducing
Signal Detection, Psychological
Sensitivity and Specificity
Nuclear Export Signals
Gene Expression Regulation
Cumulative Trauma Disorders
STAT3 Transcription Factor
Computer Storage Devices
Hospital Information Systems
Protein Processing, Post-Translational
Communication Aids for Disabled
Image Interpretation, Computer-Assisted
Promoter Regions, Genetic
Nucleic Acid Conformation
Green Fluorescent Proteins
Receptors, Cell Surface
Sequence Analysis, DNA
Magnetic Resonance Spectroscopy
Electron Spin Resonance Spectroscopy
Mitogen-Activated Protein Kinases
Monte Carlo Method
Medical Informatics Applications
In Situ Hybridization
Amino Acid Motifs
Ambulatory Care Information Systems
Information Storage and Retrieval
Tumor Cells, Cultured
Sequence Homology, Nucleic Acid
Reverse Transcriptase Polymerase Chain Reaction
Gene Expression Regulation, Bacterial
Evaluation Studies as Topic
Active Transport, Cell Nucleus
Analysis of Variance
Polymerase Chain Reaction
Tomography, X-Ray Computed
Data Interpretation, Statistical
Gene Expression Profiling
Equipment Failure Analysis
Dose-Response Relationship, Drug
Intracellular Signaling Peptides and Proteins
Phase reversal of biomechanical functions and muscle activity in backward pedaling. (1/3966)Computer simulations of pedaling have shown that a wide range of pedaling tasks can be performed if each limb has the capability of executing six biomechanical functions, which are arranged into three pairs of alternating antagonistic functions. An Ext/Flex pair accelerates the limb into extension or flexion, a Plant/Dorsi pair accelerates the foot into plantarflexion or dorsiflexion, and an Ant/Post pair accelerates the foot anteriorly or posteriorly relative to the pelvis. Because each biomechanical function (i.e., Ext, Flex, Plant, Dorsi, Ant, or Post) contributes to crank propulsion during a specific region in the cycle, phasing of a muscle is hypothesized to be a consequence of its ability to contribute to one or more of the biomechanical functions. Analysis of electromyogram (EMG) patterns has shown that this biomechanical framework assists in the interpretation of muscle activity in healthy and hemiparetic subjects during forward pedaling. Simulations show that backward pedaling can be produced with a phase shift of 180 degrees in the Ant/Post pair. No phase shifts in the Ext/Flex and Plant/Dorsi pairs are then necessary. To further test whether this simple yet biomechanically viable strategy may be used by the nervous system, EMGs from 7 muscles in 16 subjects were measured during backward as well as forward pedaling. As predicted, phasing in vastus medialis (VM), tibialis anterior (TA), medial gastrocnemius (MG), and soleus (SL) were unaffected by pedaling direction, with VM and SL contributing to Ext, MG to Plant, and TA to Dorsi. In contrast, phasing in biceps femoris (BF) and semimembranosus (SM) were affected by pedaling direction, as predicted, compatible with their contribution to the directionally sensitive Post function. Phasing of rectus femoris (RF) was also affected by pedaling direction; however, its ability to contribute to the directionally sensitive Ant function may only be expressed in forward pedaling. RF also contributed significantly to the directionally insensitive Ext function in both forward and backward pedaling. Other muscles also appear to have contributed to more than one function, which was especially evident in backward pedaling (i.e. , BF, SM, MG, and TA to Flex). We conclude that the phasing of only the Ant and Post biomechanical functions are directionally sensitive. Further, we suggest that task-dependent modulation of the expression of the functions in the motor output provides this biomechanics-based neural control scheme with the capability to execute a variety of lower limb tasks, including walking. (+info)
Varying the degree of single-whisker stimulation differentially affects phases of intrinsic signals in rat barrel cortex. (2/3966)Using intrinsic signal optical imaging (ISI), we have shown previously that the point spread of evoked activity in the rat barrel cortex in response to single-whisker stimulation encompasses a surprisingly large area. Given that our typical stimulation consists of five deflections at 5 Hz, the large area of evoked activity might have resulted from repetitive stimulation. Thus in the present study, we use ISI through the thinned skull to determine whether decreasing the degree of single-whisker stimulation decreases the area of the cortical point spread. We additionally outline a protocol to quantify stimulus-related differences in the temporal characteristics of intrinsic signals at a fine spatial scale. In 10 adult rats, whisker C2 was stimulated randomly with either one or five deflections delivered in a rostral-to-caudal fashion. Each deflection consisted of a 0.5-mm displacement of the whisker as measured at the point of contact, 15 mm from the snout. The number of whisker deflections did not affect the area or peak magnitude of the cortical point spread based on the intrinsic signal activity occurring from 0.5 up to 1.5 s poststimulus onset. In contrast, the magnitude and time course of intrinsic signal activity collected after 1.5-s poststimulus onset did reflect the difference in the degree of stimulation. Thus decreasing the degree of stimulation differentially affected the early and late phases of the evoked intrinsic signal response. The implications of the present results are discussed in respect to probable differences in the signal source underlying the early versus later phases of evoked intrinsic signals. (+info)
A new filtering algorithm for medical magnetic resonance and computer tomography images. (3/3966)Inner views of tubular structures based on computer tomography (CT) and magnetic resonance (MR) data sets may be created by virtual endoscopy. After a preliminary segmentation procedure for selecting the organ to be represented, the virtual endoscopy is a new postprocessing technique using surface or volume rendering of the data sets. In the case of surface rendering, the segmentation is based on a grey level thresholding technique. To avoid artifacts owing to the noise created in the imaging process, and to restore spurious resolution degradations, a robust Wiener filter was applied. This filter working in Fourier space approximates the noise spectrum by a simple function that is proportional to the square root of the signal amplitude. Thus, only points with tiny amplitudes consisting mostly of noise are suppressed. Further artifacts are avoided by the correct selection of the threshold range. Afterwards, the lumen and the inner walls of the tubular structures are well represented and allow one to distinguish between harmless fluctuations and medically significant structures. (+info)
Image processing strategies in picture archiving and communication systems. (4/3966)An image processing strategy is presented that assures very similar soft-copy presentation on diagnostic workstations of a picture archiving and communication system (PACS) over the lifetime of an image file and simultaneously provides efficient work-flow. The strategy is based on rigid partitioning of image processing into application- and display-device-specific processing. Application-specific processing is optimized for a reference display system. A description of this system is attached to the file header of the application-specifically processed image which is stored in the PACS. Every diagnostic display system automatically reproduces the image quality for which the application-specific processing was optimized by adjusting its properties by display-system-specific processing so that the system becomes effectively equal to the reference display system. (+info)
A new tool for measuring the suckling stimulus during breastfeeding in humans: the orokinetogram and the Fourier series. (5/3966)The Fourier series was used to analyse the oral movements recorded by the orokinetogram during breastfeeding in human babies. This is a new method that allows recording of oral movements without introducing any extrinsic element between the nipple and the mouth of the baby. The advantage of displaying suckling activity after fast Fourier transform (FFT) is that this algorithm allows storage, quantification and frequency analysis of the oral movements throughout a suckling bout, which enables the total oral activity to be measured. Two types of oral movements are found: slow high amplitude (SHA) and fast low amplitude (FLA). FLA movements may be derived from peristaltic movements of the tongue that result in tickling stimuli to the mechanoreceptors of the nipple and milk expression. The frequency bandwidth of oral movements is wider (0-8 Hz) than has been described previously (0-3 Hz) and this is due to the presence of the FLA oral movements. An indirect measurement of the energy of oral movements during suckling is obtained by the pattern of energy distribution used in each individual frequency band by oral movements. This pattern changes in relation to the periods of continuous and intermittent suckling activity. SHA and FLA oral movements are more intense during continuous suckling. Statistical analysis showed a correlation between the energy of SHA and FLA waves throughout the suckling bout, and also that the highest level of energy during suckling activity is displayed during the first 2 min. The novel tools described in this paper allow investigation of the role of suckling stimulus in reflex hormone release and other mother-infant interactions. (+info)
Ryanodine and the left ventricular force-interval and relaxation-interval relations in closed-chest dogs: insights on calcium handling. (6/3966)OBJECTIVE: Although the myocardial force-interval and relaxation-interval relations are considered to be mechanical expressions of myocardial Ca2+ handling, correlation of these phenomena with altered Ca2+ kinetics in the intact state is limited. Thus, I sought to determine the impact of selective impairment of physiologic sarcoplasmic reticulum Ca2+ release, achieved by the use of the drug ryanodine, on these relations in the intact animal. METHODS: Twelve dogs instrumented with left ventricular manometers and piezoelectric dimension crystals were studied before and after ryanodine (4 micrograms/kg intravenously). End-systolic elastance was measured at paced heart rates of 120-180 bpm to determine the force-frequency response. Mechanical restitution and relaxation restitution were determined by measuring contractile (single beat elastance) and relaxation (peak negative dP/dt) responses for beats delivered at graded extrasystolic intervals, with normalized responses expressed as a function of extrasystolic interval. RESULTS: Ryanodine accelerated mechanical restitution (time constant 60.3 +/- 3.9 versus 81.7 +/- 10.1 ms, p < 0.05) and reduced maximal contractile response (107.5 +/- 2.1 versus 122.1 +/- 5.7%, p < 0.05), slowed early relaxation restitution (time constant 65.5 +/- 13.8 versus 36.8 +/- 3.8 ms, p < 0.05) without changing late relaxation restitution kinetics, and amplified the force-frequency response (end-systolic elastance, 180 bpm, 19.4 +/- 4.3 versus 11.4 +/- 1.2 mm Hg/ml, p < 0.05). CONCLUSIONS: These findings suggest that in the intact animal, Ca2+ handling by the sarcoplasmic reticulum is a primary determinant of mechanical restitution and early relaxation restitution, but not late relaxation restitution. Conversely, ryanodine induced augmentation of the force-frequency response indicates a central role for sarcolemmal Ca2+ influx in producing frequency potentiation. (+info)
Delayed rectifier potassium current in undiseased human ventricular myocytes. (7/3966)OBJECTIVE: The purpose of the study was to investigate the properties of the delayed rectifier potassium current (IK) in myocytes isolated from undiseased human left ventricles. METHODS: The whole-cell configuration of the patch-clamp technique was applied in 28 left ventricular myocytes from 13 hearts at 35 degrees C. RESULTS: An E-4031 sensitive tail current identified the rapid component of IK (IKr) in the myocytes, but there was no evidence for an E-4031 insensitive slow component of IK (IKs). When nifedipine (5 microM) was used to block the inward calcium current (ICa), IKr activation was fast (tau = 31.0 +/- 7.4 ms, at +30 mV, n = 5) and deactivation kinetics were biexponential and relatively slow (tau 1 = 600.0 +/- 53.9 ms and tau 2 = 6792.2 +/- 875.7 ms, at -40 mV, n = 7). Application of CdCl2 (250 microM) to block ICa altered the voltage dependence of the IKr considerably, slowing its activation (tau = 657.1 +/- 109.1 ms, at +30 mV, n = 5) and accelerating its deactivation (tau = 104.0 +/- 18.5 ms, at -40 mV, n = 8). CONCLUSIONS: In undiseased human ventricle at 35 degrees C IKr exists having fast activation and slow deactivation kinetics; however, there was no evidence found for an expressed IKs. IKr probably plays an important role in the frequency dependent modulation of repolarization in undiseased human ventricle, and is a target for many Class III antiarrhythmic drugs. (+info)
Neurocardiac and cerebral responses evoked by esophageal vago-afferent stimulation in humans: effect of varying intensities. (8/3966)OBJECTIVE: This study was designed to determine whether esophageal vago-afferent electrostimulation, over a wide range of stimulus intensities, can sustain a cardiac vago-efferent effect by way of central nervous system processing. METHODS: Studies were performed in ten healthy male subjects (23.9 +/- 6.3 years). Esophageal electrostimulation was carried out using a stimulating electrode placed in the distal esophagus. Stimulation of esophageal vago-afferent fibres was employed using electrical impulses (200 microseconds at 0.2 Hz x 128 s) varying from 2.7 to 20 mA. Respiratory frequencies, beat-to-beat heart rate autospectra and cerebral evoked potentials were recorded at baseline and at each stimulus intensity in random order. RESULTS: With esophageal electrical stimulation, we observed a small non-significant decrease in heart rate. There was a dramatic shift of the instantaneous heart rate power spectra towards enhanced cardiac vagal modulation with intensities as low as 5 mA. This effect was sustained throughout all intensities with no further change in either the low frequency or high frequency power. Conversely, there was a linear dose response relationship between cerebral evoked potential amplitude and stimulus intensity mainly occurring above perception threshold (10 mA). Esophageal stimulation had no significant effect on heart rate or respiratory frequency at any stimulus intensity. CONCLUSIONS: These results indicate that electrical stimulation of the distal esophagus across a wide range of current intensities elicits a reproducible shift in the heart rate power spectrum towards enhanced vagal modulation. The data suggest a closed loop afferent/efferent circuitry wherein tonic visceral afferent impulses appear to elicit a phasic or modulatory vago-efferent cardiac response in healthy subjects. (+info)
The term "cumulative" refers to the gradual buildup of damage over time, as opposed to a single traumatic event that causes immediate harm. The damage can result from repetitive motions, vibrations, compressive forces, or other forms of stress that accumulate and lead to tissue injury and inflammation.
Some common examples of CTDs include:
1. Carpal tunnel syndrome: A condition that affects the wrist and hand, caused by repetitive motion and compression of the median nerve.
2. Tendinitis: Inflammation of a tendon, often caused by repetitive motion or overuse.
3. Bursitis: Inflammation of a bursa, a fluid-filled sac that cushions joints and reduces friction between tissues.
4. Tennis elbow: A condition characterized by inflammation of the tendons on the outside of the elbow, caused by repetitive gripping or twisting motions.
5. Plantar fasciitis: Inflammation of the plantar fascia, a band of tissue that runs along the bottom of the foot, caused by repetitive strain and overuse.
6. Repetitive stress injuries: A broad category of injuries caused by repetitive motion, such as typing or using a computer mouse.
7. Occupational asthma: A condition caused by inhaling allergens or irritants in the workplace, leading to inflammation and narrowing of the airways.
8. Hearing loss: Damage to the inner ear or auditory nerve caused by exposure to loud noises over time.
9. Vibration white finger: A condition that affects the hands, causing whiteness or loss of blood flow in the fingers due to exposure to vibrating tools.
10. Carpal tunnel syndrome: Compression of the median nerve in the wrist, leading to numbness, tingling, and weakness in the hand and arm.
It's important to note that these conditions can have a significant impact on an individual's quality of life, ability to work, and overall well-being. If you are experiencing any of these conditions, it is important to seek medical attention to receive proper diagnosis and treatment.
1. Osteoarthritis: A degenerative joint disease that affects the cartilage and bone in the joints, leading to pain, stiffness, and limited mobility.
2. Rheumatoid arthritis: An autoimmune disorder that causes inflammation in the joints, leading to pain, swelling, and deformity.
3. Fibromyalgia: A chronic condition characterized by widespread muscle pain, fatigue, and sleep disturbances.
4. Tendinitis: Inflammation of a tendon, which can cause pain and stiffness in the affected area.
5. Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion joints, leading to pain, swelling, and limited mobility.
6. Carpal tunnel syndrome: Compression of the median nerve in the wrist, leading to numbness, tingling, and weakness in the hand and fingers.
7. Sprains and strains: Injuries to the ligaments or muscles, often caused by sudden twisting or overstretching.
8. Back pain: Pain in the back that can be caused by a variety of factors, such as muscle strain, herniated discs, or spinal stenosis.
9. Osteoporosis: A condition characterized by weak and brittle bones, leading to an increased risk of fractures.
10. Clubfoot: A congenital deformity in which the foot is turned inward and downward.
These are just a few examples of musculoskeletal diseases, and there are many more conditions that can affect the muscles, bones, and joints. Treatment options for these conditions can range from conservative methods such as physical therapy and medication to surgical interventions. It's important to seek medical attention if you experience any persistent or severe symptoms in your musculoskeletal system.
The shoulder is a complex joint that consists of several bones, muscles, tendons, and ligaments, which work together to provide a wide range of motion and stability. Any disruption in this delicate balance can cause pain and dysfunction.
Some common causes of shoulder pain include:
1. Rotator cuff injuries: The rotator cuff is a group of muscles and tendons that surround the shoulder joint, providing stability and mobility. Injuries to the rotator cuff can cause pain and weakness in the shoulder.
2. Bursitis: Bursae are small fluid-filled sacs that cushion the joints and reduce friction between the bones, muscles, and tendons. Inflammation of the bursae (bursitis) can cause pain and swelling in the shoulder.
3. Tendinitis: Tendinitis is inflammation of the tendons, which connect the muscles to the bones. Tendinitis in the shoulder can cause pain and stiffness.
4. Dislocations: A dislocation occurs when the ball of the humerus (upper arm bone) is forced out of the shoulder socket. This can cause severe pain, swelling, and limited mobility.
5. Osteoarthritis: Osteoarthritis is a degenerative condition that affects the joints, including the shoulder. It can cause pain, stiffness, and limited mobility.
6. Frozen shoulder: Also known as adhesive capsulitis, frozen shoulder is a condition where the connective tissue in the shoulder joint becomes inflamed and scarred, leading to pain and stiffness.
7. Labral tears: The labrum is a cartilage ring that surrounds the shoulder socket, providing stability and support. Tears to the labrum can cause pain and instability in the shoulder.
8. Fractures: Fractures of the humerus, clavicle, or scapula (shoulder blade) can cause pain, swelling, and limited mobility.
9. Rotator cuff tears: The rotator cuff is a group of muscles and tendons that provide stability and support to the shoulder joint. Tears to the rotator cuff can cause pain and weakness in the shoulder.
10. Impingement syndrome: Impingement syndrome occurs when the tendons of the rotator cuff become pinched or compressed as they pass through the shoulder joint, leading to pain and inflammation.
These are just a few examples of common shoulder injuries and conditions. If you're experiencing shoulder pain or stiffness, it's important to see a doctor for proper diagnosis and treatment.
Asthenopia is a common condition that affects millions of people worldwide, particularly those who spend long hours working on computers, reading, or engaging in other visually demanding activities. It can also be triggered by other factors such as poor lighting, incorrect posture, and eye conditions like myopia (nearsightedness) or hyperopia (farsightedness).
While asthenopia is usually a temporary condition that resolves on its own after resting the eyes, it can sometimes be a symptom of a more serious underlying eye condition. Therefore, if you experience persistent or severe symptoms of asthenopia, it's important to consult an eye care professional for proper evaluation and treatment.
Treatment options for asthenopia may include taking regular breaks to rest the eyes, adjusting lighting conditions, using artificial tears to lubricate dry eyes, and making changes to your workspace or reading habits to reduce visual strain. In some cases, prescription eyewear or vision therapy may be necessary to address underlying eye conditions that contribute to asthenopia.
1. Asbestosis: a lung disease caused by inhaling asbestos fibers.
2. Carpal tunnel syndrome: a nerve disorder caused by repetitive motion and pressure on the wrist.
3. Mesothelioma: a type of cancer caused by exposure to asbestos.
4. Pneumoconiosis: a lung disease caused by inhaling dust from mining or other heavy industries.
5. Repetitive strain injuries: injuries caused by repetitive motions, such as typing or using vibrating tools.
6. Skin conditions: such as skin irritation and dermatitis caused by exposure to chemicals or other substances in the workplace.
7. Hearing loss: caused by loud noises in the workplace.
8. Back injuries: caused by lifting, bending, or twisting.
9. Respiratory problems: such as asthma and other breathing difficulties caused by exposure to chemicals or dust in the workplace.
10. Cancer: caused by exposure to carcinogens such as radiation, certain chemicals, or heavy metals in the workplace.
Occupational diseases can be difficult to diagnose and treat, as they often develop gradually over time and may not be immediately attributed to the work environment. In some cases, these diseases may not appear until years after exposure has ended. It is important for workers to be aware of the potential health risks associated with their job and take steps to protect themselves, such as wearing protective gear, following safety protocols, and seeking regular medical check-ups. Employers also have a responsibility to provide a safe work environment and follow strict regulations to prevent the spread of occupational diseases.
There are several types of neck pain, including:
* Acute neck pain: This is a sudden onset of pain in the neck, often caused by an injury or strain.
* Chronic neck pain: This is persistent pain in the neck that lasts for more than 3 months.
* Mechanical neck pain: This is pain caused by misalignment or degeneration of the spinal bones and joints in the neck.
* Non-mechanical neck pain: This is pain that is not caused by a specific structural problem, but rather by factors such as poor posture, muscle strain, or pinched nerves.
Neck pain can be treated with a variety of methods, including:
* Medications such as pain relievers and anti-inflammatory drugs
* Physical therapy to improve range of motion and strength
* Chiropractic care to realign the spine and relieve pressure on nerves
* Massage therapy to relax muscles and improve circulation
* Lifestyle changes such as improving posture, losing weight, and taking regular breaks to rest and stretch.
It is important to seek medical attention if neck pain is severe, persistent, or accompanied by other symptoms such as numbness, tingling, or weakness in the arms or legs.
Neoplasm refers to an abnormal growth of cells that can be benign (non-cancerous) or malignant (cancerous). Neoplasms can occur in any part of the body and can affect various organs and tissues. The term "neoplasm" is often used interchangeably with "tumor," but while all tumors are neoplasms, not all neoplasms are tumors.
Types of Neoplasms
There are many different types of neoplasms, including:
1. Carcinomas: These are malignant tumors that arise in the epithelial cells lining organs and glands. Examples include breast cancer, lung cancer, and colon cancer.
2. Sarcomas: These are malignant tumors that arise in connective tissue, such as bone, cartilage, and fat. Examples include osteosarcoma (bone cancer) and soft tissue sarcoma.
3. Lymphomas: These are cancers of the immune system, specifically affecting the lymph nodes and other lymphoid tissues. Examples include Hodgkin lymphoma and non-Hodgkin lymphoma.
4. Leukemias: These are cancers of the blood and bone marrow that affect the white blood cells. Examples include acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL).
5. Melanomas: These are malignant tumors that arise in the pigment-producing cells called melanocytes. Examples include skin melanoma and eye melanoma.
Causes and Risk Factors of Neoplasms
The exact causes of neoplasms are not fully understood, but there are several known risk factors that can increase the likelihood of developing a neoplasm. These include:
1. Genetic predisposition: Some people may be born with genetic mutations that increase their risk of developing certain types of neoplasms.
2. Environmental factors: Exposure to certain environmental toxins, such as radiation and certain chemicals, can increase the risk of developing a neoplasm.
3. Infection: Some neoplasms are caused by viruses or bacteria. For example, human papillomavirus (HPV) is a common cause of cervical cancer.
4. Lifestyle factors: Factors such as smoking, excessive alcohol consumption, and a poor diet can increase the risk of developing certain types of neoplasms.
5. Family history: A person's risk of developing a neoplasm may be higher if they have a family history of the condition.
Signs and Symptoms of Neoplasms
The signs and symptoms of neoplasms can vary depending on the type of cancer and where it is located in the body. Some common signs and symptoms include:
1. Unusual lumps or swelling
4. Weight loss
5. Change in bowel or bladder habits
6. Unexplained bleeding
7. Coughing up blood
8. Hoarseness or a persistent cough
9. Changes in appetite or digestion
10. Skin changes, such as a new mole or a change in the size or color of an existing mole.
Diagnosis and Treatment of Neoplasms
The diagnosis of a neoplasm usually involves a combination of physical examination, imaging tests (such as X-rays, CT scans, or MRI scans), and biopsy. A biopsy involves removing a small sample of tissue from the suspected tumor and examining it under a microscope for cancer cells.
The treatment of neoplasms depends on the type, size, location, and stage of the cancer, as well as the patient's overall health. Some common treatments include:
1. Surgery: Removing the tumor and surrounding tissue can be an effective way to treat many types of cancer.
2. Chemotherapy: Using drugs to kill cancer cells can be effective for some types of cancer, especially if the cancer has spread to other parts of the body.
3. Radiation therapy: Using high-energy radiation to kill cancer cells can be effective for some types of cancer, especially if the cancer is located in a specific area of the body.
4. Immunotherapy: Boosting the body's immune system to fight cancer can be an effective treatment for some types of cancer.
5. Targeted therapy: Using drugs or other substances to target specific molecules on cancer cells can be an effective treatment for some types of cancer.
Prevention of Neoplasms
While it is not always possible to prevent neoplasms, there are several steps that can reduce the risk of developing cancer. These include:
1. Avoiding exposure to known carcinogens (such as tobacco smoke and radiation)
2. Maintaining a healthy diet and lifestyle
3. Getting regular exercise
4. Not smoking or using tobacco products
5. Limiting alcohol consumption
6. Getting vaccinated against certain viruses that are associated with cancer (such as human papillomavirus, or HPV)
7. Participating in screening programs for early detection of cancer (such as mammograms for breast cancer and colonoscopies for colon cancer)
8. Avoiding excessive exposure to sunlight and using protective measures such as sunscreen and hats to prevent skin cancer.
It's important to note that not all cancers can be prevented, and some may be caused by factors that are not yet understood or cannot be controlled. However, by taking these steps, individuals can reduce their risk of developing cancer and improve their overall health and well-being.
Types: There are several types of arm injuries, including:
1. Fractures: A break in one or more bones of the arm.
2. Sprains: Stretching or tearing of ligaments that connect bones to other tissues.
3. Strains: Tears in muscles or tendons.
4. Dislocations: When a bone is forced out of its normal position in the joint.
5. Tendinitis: Inflammation of the tendons, which can cause pain and stiffness in the arm.
6. Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion the joints and reduce friction.
7. Cuts or lacerations: Open wounds on the skin or other tissues of the arm.
8. Burns: Damage to the skin and underlying tissues caused by heat, chemicals, or electricity.
9. Nerve injuries: Damage to the nerves that control movement and sensation in the arm.
10. Infections: Bacterial, viral, or fungal infections that can affect any part of the arm.
Symptoms: The symptoms of arm injuries can vary depending on the type and severity of the injury. Some common symptoms include pain, swelling, bruising, limited mobility, deformity, and difficulty moving the arm.
Diagnosis: A healthcare professional will typically perform a physical examination and may use imaging tests such as X-rays, CT scans, or MRI to diagnose arm injuries.
Treatment: Treatment for arm injuries can range from conservative methods such as rest, ice, compression, and elevation (RICE) to surgical interventions. The goal of treatment is to relieve pain, promote healing, and restore function to the affected arm.
1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.
2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.
3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.
4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.
5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.
6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.
7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.
8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.
9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.
10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.
There are different types of Breast Neoplasms such as:
1. Fibroadenomas: These are benign tumors that are made up of glandular and fibrous tissues. They are usually small and round, with a smooth surface, and can be moved easily under the skin.
2. Cysts: These are fluid-filled sacs that can develop in both breast tissue and milk ducts. They are usually benign and can disappear on their own or be drained surgically.
3. Ductal Carcinoma In Situ (DCIS): This is a precancerous condition where abnormal cells grow inside the milk ducts. If left untreated, it can progress to invasive breast cancer.
4. Invasive Ductal Carcinoma (IDC): This is the most common type of breast cancer and starts in the milk ducts but grows out of them and invades surrounding tissue.
5. Invasive Lobular Carcinoma (ILC): It originates in the milk-producing glands (lobules) and grows out of them, invading nearby tissue.
Breast Neoplasms can cause various symptoms such as a lump or thickening in the breast or underarm area, skin changes like redness or dimpling, change in size or shape of one or both breasts, discharge from the nipple, and changes in the texture or color of the skin.
Treatment options for Breast Neoplasms may include surgery such as lumpectomy, mastectomy, or breast-conserving surgery, radiation therapy which uses high-energy beams to kill cancer cells, chemotherapy using drugs to kill cancer cells, targeted therapy which uses drugs or other substances to identify and attack cancer cells while minimizing harm to normal cells, hormone therapy, immunotherapy, and clinical trials.
It is important to note that not all Breast Neoplasms are cancerous; some are benign (non-cancerous) tumors that do not spread or grow.
Magnetic resonance imaging
History of IBM research in Israel
Process tracing in psychology
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Electronic musical instrument
Coordinated Science Laboratory
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Human presence detection
Sound and Music Computing Conference
Total intravenous anaesthesia
Government Engineering College, Hassan
General-purpose computing on graphics processing units
Graph cut optimization
Robert S. Singleton
Occupation of the Malheur National Wildlife Refuge
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2022 in the United States
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Center for Nonlinear and Complex Systems at Duke University
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Parallel computation of simple arithmetic using peptide-antibody interactions - IIT Madras
Fast algorithm for distortion-based error protection of embedded image codes. - Texas A&M University (TAMU) Scholar
Compressive sensing beamforming based on covariance for acoustic imaging with noisy measurements: Journal of the Acoustical...
Central Library, KUET catalog › ISBD view
Upcoming International image-processing Conferences in australia 2023
Ismail Ben Ayed | ÉTS Montréal
Publication List | Data Analysis and Modeling in Medicine
Large-scale probabilistic functional modes from resting state fMRI. - Department of Psychiatry
k-t FASTER: Acceleration of functional MRI data acquisition using low rank constraints. - Oxford Big Data Institute
ZEISS Innovation Hub Karlsruhe
Mobile-assisted prosody training for limited english proficiency: Learner background and speech learning pattern<...
Improved Channel Capacity in 5G Ultradense Network
Upcoming Image Processing Conferences 2023 | All Conference Alert
Structural imaging of the cervical spinal cord with suppressed CSF signal using DANTE pulse trains. - Radcliffe Department of...
Trial-by-trial fluctuations in the event-related electroencephalogram reflect dynamic changes in the degree of surprise. -...
Publications | The Perk Lab
Download ebook: Mri Brian M Dale | FaroLight Publishing
10th International Conference on Chemical and Biological Sciences (ICCBS 2023), 08-11 Jun 2023 | Conference Locate (Clocate)
- This book provides an emphasis on brain and behavior computing with different modalities available such as signal processing, image processing, data sciences, statistics further it includes fundamental, mathematical model, algorithms, case studies, and future research scopes. (farolightpublishing.com)
- Algorithms and software development are given in each chapter to reproduce the computer simulated results described therein. (farolightpublishing.com)
- EURASIP journal on advances in signal processing 2022 0 0. (cdc.gov)
- The following lists all the past chairs and members of the SPS Bio Imaging and Signal Processing Technical Committee. (signalprocessingsociety.org)
- The purpose of the Bio Imaging and Signal Processing Technical Committee (BISP TC) is to promote activities within the broad technical field of biomedical image and signal processing. (signalprocessingsociety.org)
- Specific areas of interest include (but are not limited to) biomedical imaging, molecular imaging, microscopy, computational image processing, and signal processing in computational biology and bioinformatics. (signalprocessingsociety.org)
- Information Processing in Medical Imaging. (etsmtl.ca)
- Structural imaging of the cervical spinal cord with suppressed CSF signal using DANTE pulse trains. (ox.ac.uk)
- CONCLUSION: DANTE prepared imaging techniques for moving CSF signal attenuation are promising tools for cervical spinal cord imaging. (ox.ac.uk)
- On Pattern Recognition And Information Processing , 140-143. (uni-heidelberg.de)
- International journal of computer assisted radiology and surgery 2021 2 0. (cdc.gov)
- Australia is gearing up to host a series of highly anticipated image-processing conferences in australia 2023, attracting professionals, researchers, and innovators from across the globe. (internationalconferencealerts.com)
- A compressive sensing beamforming method (CSB-II) is developed based on sampling covariance matrix, assuming spatially sparse and incoherent signals, and then examined using both simulations and aeroacoustic measurements. (edu.hk)
- However, the formal computational processes underlying the generation of the P300 are not well known. (ox.ac.uk)
- Precise detection of specific artefacts like pixel saturations, motion blur, specular reflections, bubbles and debris is essential for high-quality frame restoration and is crucial for realising reliable computer-assisted tools for improved patient care. (signalprocessingsociety.org)
- CIDARS further facilitates the data analysis, aberration detection, signal dissemination, signal response and information communication needed by public health departments across the country. (who.int)
- It assists with early outbreak detection at the local level and prompts reporting of unusual disease occurrences or potential outbreaks to CDCs throughout the country. (who.int)
- Workshop Proceedings of the 22nd International Conference on Computers in Education, ICCE 2014). (ntnu.edu.tw)
- 2001. " Computer-Assisted Surgery: Developments And Prospects In 2001 " . (uni-heidelberg.de)
- These events will provide you with a platform for exchanging knowledge, advancements, and ideas in the field of image-processing. (internationalconferencealerts.com)
- Also, these image-processing conferences in australia will offer you great opportunities for networking, collaboration, and learning. (internationalconferencealerts.com)
- Medical Image Computing and Computer-Assisted Intervention - MICCAI 2012. (etsmtl.ca)
- 2004 International Conference on Image Processing, 2004. (etsmtl.ca)
- Medical Image Computing and Computer-Assisted Intervention - MICCAI 2014. (etsmtl.ca)
- In 3Rd Wseas International Conference On Signal, Speech And Image Processing (Icossip2003) , 2:874-878. (uni-heidelberg.de)
- 2000. " Distributed Web-Based Image Processing Tool " . (uni-heidelberg.de)
- Second, AI can learn from data without any labels or annotations (e.g. image labelled with a known medical diagnosis), a process known as unsupervised learning. (cdc.gov)
- Signal processing -- Mathematics. (hacettepe.edu.tr)
- The P300 component of the human event-related brain potential has often been linked to the processing of rare, surprising events. (ox.ac.uk)
- It further illustrates brain signal sources and how the brain signal can process, manipulate, and transform in different domains allowing researchers and professionals to extract information about the physiological condition of the brain. (farolightpublishing.com)
- Emphasizes real challenges in brain signal processing for a variety of applications for analysis, classification, and clustering. (farolightpublishing.com)
- Augments the use of data mining and machine learning to brain computer interface (BCI) devices. (farolightpublishing.com)
- For example, AI was recently applied to EEG signals from clinically unresponsive patients with brain injuries to detect brain activity, an important predictor of long-term recovery. (cdc.gov)
- ISPACS 2013 - 2013 International Symposium on Intelligent Signal Processing and Communication Systems). (ntnu.edu.tw)
- Such differences allow some individuals to disabilities need special methods and tools to access computers still have mastery of neck and oral musculature functions and, 1. (bvsalud.org)
- AI methods have been used to predict outcomes from medical signal data, such as electroencephalograms (EEG), electrocardiograms, and audio data. (cdc.gov)
- The universal availability of modern communication tools (such as computers, the Internet and mobile phones) in China also helped this idea to be realized. (who.int)
- A deep adversarial model for segmentation-assisted COVID-19 diagnosis using CT images. (cdc.gov)
- ABSTRACT "E-health" is a generic term covering the use of computer and communication applications and technologies in health and medical care. (who.int)
- Timely reporting, effective analyses and rapid distribution of surveillance data can assist in detecting the aberration of disease occurrence and further facilitate a timely response. (who.int)
- Systems Group (MSG) list-assisted RDD system can screen out a portion of the nonworking numbers as a preliminary sample preparation activity. (cdc.gov)
- abstract = "The use of Mobile-Assisted Pronunciation Training (MAPT) has been increasing drastically due to the personal and interactive nature of mobile devices. (nau.edu)
- The NIS collects data by computer assisted telephone interviews (CATI) from a random sample of households in the 78 Immunization Action Plan (IAP) areas. (cdc.gov)
- Data collected to determine current state revealed assisted by an operations director (project champion) and an outside that only 20% of positive blood cultures were finalized consultant. (who.int)
- Data collected pre- and post- investigate blood cultures signaled as positive, review of changes were tabulated and reviewed. (who.int)
- PROBLEM STATEMENT In our laboratory, only process by identifying each step, removing non-value added steps, 19% of positive blood cultures are finalized with and eliminating waste. (who.int)
- The laboratory was cleaned, de-cluttered, and organized culture processing identified to have an impact on this to achieve standardization and to decrease unnecessary waiting and figure were: time to accession blood cultures, time to motion. (who.int)
- Asia-Pacific Society for Computers in Education , p. 48-55 8 p. (ntnu.edu.tw)
- The Internet, computers and mobile phones are used to accomplish rapid signal generation and dissemination, timely reporting and reviewing of the signal response results. (who.int)
- Computer Vision - ACCV 2007. (etsmtl.ca)
- We hypothesized that the contrast between spinal cord and cerebrospinal fluid (CSF) could be maximized due to moving CSF signal suppression. (ox.ac.uk)
- The use of computers, tablets, and cell phones with the Internet by people with quadriplegia from spinal cord injuries is much lower when compared to the general population. (bvsalud.org)
- However, the or debilitating diseases such as polio, spinal cord tumors, level of use of the computer and the Internet by people with congenital anomalies, such as multiple sclerosis, or cerebral disabilities is still low when compared to that of the general palsy 6. (bvsalud.org)
- The statistical estimation and tests of hypotheses are based on the likelihood principle derived from stationary point processes and time series. (farolightpublishing.com)
- A device made of acrylic resin, similar to a myorelaxant plate, was designed to allow the use of a computer that was comfortable and at the same time, the patient could talk and not harm the dental structures. (bvsalud.org)
- The time to first signal as a positive blood cultures. (who.int)
- The technology we use, and even rely on, in our everyday lives -computers, radios, video, cell phones - is enabled by signal processing. (signalprocessingsociety.org)
- These 2 heterogeneous masses have a reticulated core of high and low signal intensities surrounded by a hypointense rim of hemosiderin. (medscape.com)
- Test your knowledge of signal processing history with our April trivia! (signalprocessingsociety.org)