F Factor: A plasmid whose presence in the cell, either extrachromosomal or integrated into the BACTERIAL CHROMOSOME, determines the "sex" of the bacterium, host chromosome mobilization, transfer via conjugation (CONJUGATION, GENETIC) of genetic material, and the formation of SEX PILI.Sex: The totality of characteristics of reproductive structure, functions, PHENOTYPE, and GENOTYPE, differentiating the MALE from the FEMALE organism.Conjugation, Genetic: A parasexual process in BACTERIA; ALGAE; FUNGI; and ciliate EUKARYOTA for achieving exchange of chromosome material during fusion of two cells. In bacteria, this is a uni-directional transfer of genetic material; in protozoa it is a bi-directional exchange. In algae and fungi, it is a form of sexual reproduction, with the union of male and female gametes.Extrachromosomal Inheritance: Vertical transmission of hereditary characters by DNA from cytoplasmic organelles such as MITOCHONDRIA; CHLOROPLASTS; and PLASTIDS, or from PLASMIDS or viral episomal DNA.AcridinesEscherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Genetics, Microbial: A subdiscipline of genetics which deals with the genetic mechanisms and processes of microorganisms.Coliphages: Viruses whose host is Escherichia coli.Chromosomes, Bacterial: Structures within the nucleus of bacterial cells consisting of or containing DNA, which carry genetic information essential to the cell.Lactose: A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.R Factors: A class of plasmids that transfer antibiotic resistance from one bacterium to another by conjugation.Sex Characteristics: Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.Recombination, Genetic: Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.Genes: A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms.Lysogeny: The phenomenon by which a temperate phage incorporates itself into the DNA of a bacterial host, establishing a kind of symbiotic relation between PROPHAGE and bacterium which results in the perpetuation of the prophage in all the descendants of the bacterium. Upon induction (VIRUS ACTIVATION) by various agents, such as ultraviolet radiation, the phage is released, which then becomes virulent and lyses the bacterium.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Crosses, Genetic: Deliberate breeding of two different individuals that results in offspring that carry part of the genetic material of each parent. The parent organisms must be genetically compatible and may be from different varieties or closely related species.Lactococcus lactis: A non-pathogenic species of LACTOCOCCUS found in DAIRY PRODUCTS and responsible for the souring of MILK and the production of LACTIC ACID.Drug Resistance, Microbial: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).DNA, Circular: Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Transduction, Genetic: The transfer of bacterial DNA by phages from an infected bacterium to another bacterium. This also refers to the transfer of genes into eukaryotic cells by viruses. This naturally occurring process is routinely employed as a GENE TRANSFER TECHNIQUE.Chromosome Mapping: Any method used for determining the location of and relative distances between genes on a chromosome.DNA Restriction Enzymes: Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1.Operon: In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION.Bacterial Proteins: Proteins found in any species of bacterium.Chromosomes: In a prokaryotic cell or in the nucleus of a eukaryotic cell, a structure consisting of or containing DNA which carries the genetic information essential to the cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Sex Chromosomes: The homologous chromosomes that are dissimilar in the heterogametic sex. There are the X CHROMOSOME, the Y CHROMOSOME, and the W, Z chromosomes (in animals in which the female is the heterogametic sex (the silkworm moth Bombyx mori, for example)). In such cases the W chromosome is the female-determining and the male is ZZ. (From King & Stansfield, A Dictionary of Genetics, 4th ed)Sex Determination Processes: The mechanisms by which the SEX of an individual's GONADS are fixed.Unsafe Sex: Sexual behaviors which are high-risk for contracting SEXUALLY TRANSMITTED DISEASES or for producing PREGNANCY.Genes, Bacterial: The functional hereditary units of BACTERIA.Sex Workers: People who engage in occupational sexual behavior in exchange for economic rewards or other extrinsic considerations.Sex Differentiation: The process in developing sex- or gender-specific tissue, organ, or function after SEX DETERMINATION PROCESSES have set the sex of the GONADS. Major areas of sex differentiation occur in the reproductive tract (GENITALIA) and the brain.Safe Sex: Sexual behavior that prevents or reduces the spread of SEXUALLY TRANSMITTED DISEASES or PREGNANCY.Sex Attractants: Pheromones that elicit sexual attraction or mating behavior usually in members of the opposite sex in the same species.Sex Determination Analysis: Validation of the SEX of an individual by inspection of the GONADS and/or by genetic tests.Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Disorders of Sex Development: In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure to abnormal levels of GONADAL HORMONES in the maternal environment, or disruption of the function of those hormones by ENDOCRINE DISRUPTORS are included.Sex Preselection: Methods for controlling genetic SEX of offspring.Sex Hormone-Binding Globulin: A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.Sex Counseling: Advice and support given to individuals to help them understand and resolve their sexual adjustment problems. It excludes treatment for PSYCHOSEXUAL DISORDERS or PSYCHOSEXUAL DYSFUNCTION.Gonadal Steroid Hormones: Steroid hormones produced by the GONADS. They stimulate reproductive organs, germ cell maturation, and the secondary sex characteristics in the males and the females. The major sex steroid hormones include ESTRADIOL; PROGESTERONE; and TESTOSTERONE.Prostitution: The practice of indulging in sexual relations for money.Homosexuality, Male: Sexual attraction or relationship between males.Sex Education: Education which increases the knowledge of the functional, structural, and behavioral aspects of human reproduction.Sexual Behavior: Sexual activities of humans.Chloromercurinitrophenols: Mercuriphenols substituted with one or more chlorine atoms and one or more nitro groups. Some of these are sulfhydryl reagents which act as chromophoric probes in enzymes and other proteins.Anomura: An infraorder of CRUSTACEA, in the order DECAPODA comprising the hermit crabs and characterized by a small fifth pair of legs.Games, Experimental: Games designed to provide information on hypotheses, policies, procedures, or strategies.Suppressor Factors, Immunologic: Proteins, protein complexes, or glycoproteins secreted by suppressor T-cells that inhibit either subsequent T-cells, B-cells, or other immunologic phenomena. Some of these factors have both histocompatibility (I-J) and antigen-specific domains which may be linked by disulfide bridges. They can be elicited by haptens or other antigens and may be mass-produced by hybridomas or monoclones in the laboratory.Chaperonin 10: A group I chaperonin protein that forms a lid-like structure which encloses the non-polar cavity of the chaperonin complex. The protein was originally studied in BACTERIA where it is commonly referred to as GroES protein.Game Theory: Theoretical construct used in applied mathematics to analyze certain situations in which there is an interplay between parties that may have similar, opposed, or mixed interests. In a typical game, decision-making "players," who each have their own goals, try to gain advantage over the other parties by anticipating each other's decisions; the game is finally resolved as a consequence of the players' decisions.Rejection (Psychology): Non-acceptance, negative attitudes, hostility or excessive criticism of the individual which may precipitate feelings of rejection.

Regional survey of femoral neck fractures. (1/28941)

In the South-west Thames Region 2619 patients (2105 women and 514 men) were discharged with a diagnosis of femoral neck fracture in 1974. The equivalent of a 250-bedded hospital was occupied throughout the year. The incidence, average length of stay, and mortality rate rose with increasing age and there were differences in these indices in the five health areas. These results confirm the enormous burden placed on the hospital service by patients with fracture of the femoral neck but suggest that differences in practice in the five areas may contribute to the size of the problem.  (+info)

Determination of human body burden baseline date of platinum through autopsy tissue analysis. (2/28941)

Results of analysis for platinum in 97 autopsy sets are presented. Analysis was performed by a specially developed emission spectrochemical method. Almost half of the individuals studied were found to have detectable platinum in one or more tissue samples. Platinum was found to be deposited in 13 of 21 tissue types investigated. Surprisingly high values were observed in subcutaneous fat, previously not considered to be a target site for platinum deposition. These data will serve as a human tissue platinum burden baseline in EPA's Catalyst Research Program.  (+info)

A quantitative three-dimensional model of the Drosophila optic lobes. (3/28941)

A big step in the neurobiology of Drosophila would be to establish a standard for brain anatomy to which to relate morphological, developmental and genetic data. We propose that only an average brain and its variance would be a biologically meaningful reference and have developed an averaging procedure. Here, we present a brief outline of this method and apply it to the optic lobes of Drosophila melanogaster wild-type Canton S. Whole adult brains are stained with a fluorescent neuropil marker and scanned with the confocal microscope. The resulting three-dimensional data sets are automatically aligned into a common coordinate system and intensity averages calculated. We use effect-size maps for the fast detection of differences between averages. For morphometric analysis, neuropil structures are labelled and superimposed to give a three-dimensional probabilistic map. In the present study, the method was applied to 66 optic lobes. We found their size, shape and position to be highly conserved between animals. Similarity was even higher between left and right optic lobes of the same animal. Sex differences were more pronounced. Female optic lobes were 6% larger than those of males. This value corresponds well with the higher number of ommatidia in females. As females have their additional ommatidia dorsally and ventrally, the additional neuropil in the medulla, lobula and lobula plate, accordingly, was found preferentially at these locations. For males, additional neuropil was found only at the posterior margin of the lobula. This finding supports the notion of male-specific neural processing in the lobula as described for muscid and calliphorid flies.  (+info)

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. (4/28941)

Bcl-2 is known to inhibit apoptosis and is thought to play a role in colorectal tumour development. Studies of the promoter region of bcl-2 have indicated the presence of a p53 responsive element which downregulates bcl-2 expression. Since p53 is commonly mutated in colorectal cancers, but rarely in those tumours showing microsatellite instability (MSI), the aim of this study was to examine the relationship of bcl-2 protein expression to MSI, as well as to other clinicopathological and molecular variables, in colorectal adenocarcinomas. Expression of bcl-2 was analysed by immunohistochemistry in 71 colorectal cancers which had been previously assigned to three classes depending upon their levels of MSI. MSI-high tumours demonstrated instability in three or more of six microsatellite markers tested, MSI-low tumours in one or two of six, and MSI-null in none of six. Bcl-2 expression in tumours was quantified independently by two pathologists and assigned to one of five categories, with respect to the number of cells which showed positive staining: 0, up to 5%; 1, 6-25%; 2, 26-50%; 3, 51-75%; and 4, > or =76%. Bcl-2 negative tumours were defined as those with a score of 0. Bcl-2 protein expression was tested for association with clinicopathological stage, differentiation level, tumour site, age, sex, survival, evidence of p53 inactivation and MSI level. A significant association was found between bcl-2 expression and patient survival (P = 0.012, Gehan Wilcoxon test). Further, a significant reciprocal relationship was found between bcl-2 expression and the presence of MSI (P = 0.012, Wilcoxon rank sum test). We conclude that bcl-2 expressing colorectal cancers are more likely to be MSI-null, and to be associated with improved patient survival.  (+info)

Dietary intake and practices in the Hong Kong Chinese population. (5/28941)

OBJECTIVES: To examine dietary intake and practices of the adult Hong Kong Chinese population to provide a basis for future public health recommendations with regard to prevention of certain chronic diseases such as cardiovascular disease, hypertension, and osteoporosis. PARTICIPANTS: Age and sex stratified random sample of the Hong Kong Chinese population aged 25 to 74 years (500 men, 510 women). METHOD: A food frequency method over a one week period was used for nutrient quantification, and a separate questionnaire was used for assessment of dietary habits. Information was obtained by interview. RESULTS: Men had higher intakes of energy and higher nutrient density of vitamin D, monounsaturated fatty acids and cholesterol, but lower nutrient density of protein, many vitamins, calcium, iron, copper, and polyunsaturated fatty acids. There was an age related decrease in energy intake and other nutrients except for vitamin C, sodium, potassium, and percentage of total calorie from carbohydrate, which all increased with age. Approximately 50% of the population had a cholesterol intake of < or = 300 mg; 60% had a fat intake < or = 30% of total energy; and 85% had a percentage of energy from saturated fats < or = 10%; criteria considered desirable for cardiovascular health. Seventy eight per cent of the population had sodium intake values in the range shown to be associated with the age related rise in blood pressure with age. Mean calcium intake was lower than the FAO/WHO recommendations. The awareness of the value of wholemeal bread and polyunsaturated fat spreads was lower in this population compared with that in Australia. There was a marked difference in types of cooking oil compared with Singaporeans, the latter using more coconut/palm/mixed vegetable oils. CONCLUSION: Although the current intake pattern for cardiovascular health for fat, saturated fatty acid, and cholesterol fall within the recommended range for over 50% of the population, follow up surveys to monitor the pattern would be needed. Decreasing salt consumption, increasing calcium intake, and increasing the awareness of the health value of fibre may all be beneficial in the context of chronic disease prevention.  (+info)

The five amino acid-deleted isoform of hepatocyte growth factor promotes carcinogenesis in transgenic mice. (6/28941)

Hepatocyte growth factor (HGF) is a polypeptide with mitogenic, motogenic, and morphogenic effects on different cell types including hepatocytes. HGF is expressed as two biologically active isotypes resulting from alternative RNA splicing. The roles of each HGF isoform in development, liver regeneration and tumorigenesis have not yet been well characterized. We report the generation and analysis of transgenic mice overexpressing the five amino acid-deleted variant of HGF (dHGF) in the liver by virtue of an albumin expression vector. These ALB-dHGF transgenic mice develop normally, have an enhanced rate of liver regeneration after partial hepatectomy, and exhibit a threefold higher incidence of hepatocellular carcinoma (HCC) beyond 17 months of age. Moreover, overexpression of dHGF dramatically accelerates diethyl-nitrosamine induced HCC tumorigenesis. These tumors arise faster, are significantly larger, more numerous and more invasive than those appearing in non-transgenic littermates. Approximately 90% of female dHGF-transgenic mice had multiple macroscopic HCCs 40 weeks after injection of DEN; whereas the non-transgenic counterparts had only microscopic nodules. Liver tumors and cultured tumor cell lines from dHGF transgenics showed high levels of HGF and c-Met mRNA and protein. Together, these results reveal that in vivo dHGF plays an active role in liver regeneration and HCC tumorigenesis.  (+info)

Cardiovascular disease in insulin dependent diabetes mellitus: similar rates but different risk factors in the US compared with Europe. (7/28941)

BACKGROUND: Cardiovascular disease (CVD) in insulin dependent diabetes mellitus (IDDM) has been linked to renal disease. However, little is known concerning international variation in the correlations with hyperglycaemia and standard CVD risk factors. METHODS: A cross-sectional comparison was made of prevalence rates and risk factor associations in two large studies of IDDM subjects: the Pittsburgh Epidemiology of Diabetes Complications Study (EDC) and the EURODIAB IDDM Complications Study from 31 centres in Europe. Subgroups of each were chosen to be comparable by age and duration of diabetes. The EDC population comprises 286 men (mean duration 20.1 years) and 281 women (mean duration 19.9 years); EURODIAB 608 men (mean duration 18.1 years) and 607 women (mean duration 18.9 years). The mean age of both populations was 28 years. Cardiovascular disease was defined by a past medical history of myocardial infarction, angina, and/or the Minnesota ECG codes (1.1-1.3, 4.1-4.3, 5.1-5.3, 7.1). RESULTS: Overall prevalence of CVD was similar in the two populations (i.e. men 8.6% versus 8.0%, women 7.4% versus 8.5%, EURODIAB versus EDC respectively), although EDC women had a higher prevalence of angina (3.9% versus 0.5%, P < 0.001). Multivariate modelling suggests that glycaemic control (HbA1c) is not related to CVD in men. Age and high density lipoprotein cholesterol predict CVD in EURODIAB, while triglycerides and hypertension predict CVD in EDC. For women in both populations, age and hypertension (or renal disease) are independent predictors. HbA1c is also an independent predictor-inversely in EURODIAB women (P < 0.008) and positively in EDC women (P = 0.03). Renal disease was more strongly linked to CVD in EDC than in EURODIAB. CONCLUSIONS: Despite a similar prevalence of CVD, risk factor associations appear to differ in the two study populations. Glycaemic control (HbA1c) does not show a consistent or strong relationship to CVD.  (+info)

Heart rate and subsequent blood pressure in young adults: the CARDIA study. (8/28941)

The objective of the present study was to examine the hypothesis that baseline heart rate (HR) predicts subsequent blood pressure (BP) independently of baseline BP. In the multicenter longitudinal Coronary Artery Risk Development in Young Adults study of black and white men and women initially aged 18 to 30 years, we studied 4762 participants who were not current users of antihypertensive drugs and had no history of heart problems at the baseline examination (1985-1986). In each race-sex subgroup, we estimated the effect of baseline HR on BP 2, 5, 7, and 10 years later by use of repeated measures regression analysis, adjusting for baseline BP, age, education, body fatness, physical fitness, fasting insulin, parental hypertension, cigarette smoking, alcohol consumption, oral contraceptive use, and change of body mass index from baseline. The association between baseline HR and subsequent systolic BP (SBP) was explained by multivariable adjustment. However, HR was an independent predictor of subsequent diastolic BP (DBP) regardless of initial BP and other confounders in white men, white women, and black men (0.7 mm Hg increase per 10 bpm). We incorporated the part of the association that was already present at baseline by not adjusting for baseline DBP: the mean increase in subsequent DBP was 1.3 mm Hg per 10 bpm in white men, white women, and black men. A high HR may be considered a risk factor for subsequent high DBP in young persons.  (+info)

  • Until recently I met this guy from Australia we did have anal sex, but with a condom/lubrication, to avoid too much trauma, and he did not pre-cum very much during oral sex. (thebody.com)
  • Unprotected sex was defined as any unprotected penetrative vaginal or anal sex with last two clients. (scielo.org.za)
  • A quarter of anal sex was unprotected. (scielo.org.za)
  • Tailored sex work interventions should explicitly include male and transgender sex workers, sex work-specific clinics, focus on the risks of unprotected anal sex, and include interventions to reduce harm caused by alcohol abuse. (scielo.org.za)
  • Promoting consistent condom use (CCU) during anal sex is a key risk reduction strategy for HIV prevention among MSM. (biomedcentral.com)
  • Among 1618 MSM interviewed, CCU during anal sex with regular, paying, and a casual male partner was 45.3%, 50.8% and 57.9%, respectively. (biomedcentral.com)
  • Characteristics associated with increased odds for CCU with MSM having all three types of partners combined were frequent receptive anal sex acts with regular partners (adjusted odds ratio [AOR] 2.17, 95% confidence interval [CI] 1.01-4.65), fewer number of casual partners (AOR 3.41, 95% CI 1.50-7.73) and membership in a community-based organization (CBO) for MSM (AOR 3.54, 95% CI 1.62-7.74). (biomedcentral.com)
  • That sex hormones, insulin, and obesity all correlate with the constellation of risk factors for myocardial infarction (MI) that has come to be known as "syndrome X," the "insulin-resistance syndrome," or the "metabolic syndrome" suggests that any one or more of them could underlie and link the risk factors to form the constellation. (nih.gov)
  • That sex hormones, insulin, and obesity also correlate with each other complicates their identification as an underlying link. (nih.gov)
  • To compare the likelihood of each being a link, we measured and determined the interrelationships of sex hormones, insulin, adiposity variables, and risk factors for MI in 80 apparently healthy men. (nih.gov)
  • VAT correlated more strongly with risk factors for MI than did sex hormones and insulin, and most of the correlations of sex hormones and insulin with risk factors for MI lost statistical significance after controlling for VAT. (nih.gov)
  • In conclusion, (1) VAT in men may largely explain the correlations of sex hormones, insulin, and obesity with the risk factors for MI measured, (2) VAT may be the principal factor in men, independently of other measures of adiposity, that links risk factors for MI to form the constellation, and (3) estradiol may play a more important role in the sex hormone-insulin relationship in men than has generally been considered. (nih.gov)
  • In toto, there is substantial evidence indicating that at least some of oxytocin's effects are correlated with an individual's sex, in part via the influence of gonadal hormones. (frontiersin.org)
  • The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. (indigo.ca)
  • The role of sex and sex hormones in regulating obesity-induced inflammation. (indigo.ca)
  • The team investigated several leading hypotheses that attempt to explain this phenomenon, including the idea that clinicians are not as good at recognizing autism in females, that autism represents an "extreme male brain" that is naturally more common in males, or that autism is driven by differences in sex hormones, and found that these did not appear to be major factors in the genetics of the disease. (ucsf.edu)
  • As per available reports about 1 54 journals , 84 Conferences , 12 workshops are presently dedicated exclusively to sex hormones and about 213014 articles are being published on the current trends in Sex Hormones.In terms of research annually,USA, India, Japan, Brazil and Canada are some of the leading countries where maximum studies related to Sex Hormones ar ebeing carried out. (omicsonline.org)
  • As reported in apbi page, Sex hormones are responsible for some of the most dramatic changes that occur in the body. (omicsonline.org)
  • They control puberty, egg and sperm production, pregnancy, birth and lactationn girls, between the ages of about 10 and14, the pituitary gland produces Luteinising Hormone (LH) and Follicle Stimulating Hormone (FSH) which together stimulate the production of the sex hormones by the ovaries.In boys, between the ages of about 12 and 15, the pituitary gland produces LH and FSH, which together stimulate the production of the sex hormones. (omicsonline.org)
  • Reproductive System & Sexual Disorders is an academic journal - hosted by OMICS International - a pioneer in open access publishing-and is listed among the top 10 journals in sex hormones. (omicsonline.org)
  • According to Kuhn's and others' research, the reason for this addiction disparity has to do with how dopamine interacts with the sex hormones estrogen and testosterone. (aaas.org)
  • Cushla R. McCarthny, Xin Du, YeeWen Candace Wu, and Rachel A. Hill, "Investigating the Interactive Effects of Sex Steroid Hormones and Brain-Derived Neurotrophic Factor during Adolescence on Hippocampal NMDA Receptor Expression," International Journal of Endocrinology , vol. 2018, Article ID 7231915, 12 pages, 2018. (hindawi.com)
  • This paper examines economic, sociocultural, and behavioral risk factors that influence the compensating price difference (premium paid) between sex with and without a condom for female sex workers (FSWs) in U.S.-Mexico border cities. (ssrn.com)
  • Located at Timika in Papua, the world's largest gold mine employs many single and migrant men, and sex with female sex workers (FSWs) is common. (thebody.com)
  • While some studies have focused on female sex workers (FSWs) in urban centres along major transport routes and in mining areas in SA, these studies are mostly a decade old. (scielo.org.za)
  • To determine potential social, psychological, and environmental-structural factors that may result in motivating female sex workers (FSWs), who are rural-to-urban migrants, and their paying partners in Shanghai, China to promote consistent condom use (CCU). (biomedcentral.com)
  • Environmental-structural factor support for condom use, in addition to social, psychological, and individual cognitive factors are significant predictors of CCU among FSWs, which should be assessed and addressed in research and interventions related to HIV/AIDS prevention among FSWs in China. (biomedcentral.com)
  • In many cases, female sex workers (FSWs) from the itinerant population are considered a significant contributor to the heterosexual transmission rates of HIV/STIs because their unprotected, anonymous sexual activities act as a "bridge" to spread HIV/STIs to the general population [ 5 ]. (biomedcentral.com)
  • Sibship size, sibling sex ratio, birth order, and parental age in homosexual and nonhomosexual gender dysphorics. (springer.com)
  • To test this hypothesis, we conducted gender-specific analyses of the five established aetiologic factors in a population-based case-control study in Sweden. (pubmedcentralcanada.ca)
  • Views of service providers on gender-biased sex selection and of program implementers on the impact of gender-focused programs on the importance of having daughter in the family were also gathered. (www.gov.uk)
  • The practice of disclosing the sex of the fetus is widespread in both study districts but the practice of sex-selective abortion was almost entirely absent, and women strongly opposed gender-biased pregnancy termination. (www.gov.uk)
  • The SCOR programs are large Center Programs (P50) that consist of 11 Centers that conduct interdisciplinary research focused on health issues that affect women and examine sex/gender contributions to health and disease. (nih.gov)
  • What factors are associated with reporting lacking interest in sex and how do these vary by gender? (bmj.com)
  • This case underscores the need for employers to make carefully reasoned, gender-neutral compensation decisions, based on business-related factors such as skills and experience. (jdsupra.com)
  • Measures of sexual orientation, sex typicality (recalled childhood gender nonconformity), and mating success (number of lifetime sexual partners) were completed. (uzh.ch)
  • Each participant completed a questionnaire survey and interview aimed to collect information on the perceptions and behaviors of individuals associated with a risk for human immunodeficiency virus/acquired immunodeficiency syndrome(HIV/AIDS),self-efficacy at negotiating safe sex,and the physical, social, and policy environment of the establishments where they worked. (biomedcentral.com)
  • 1.) Since my test I have only been with a few men, but all performed oral sex on them. (thebody.com)
  • 2.) Someone performed oral sex on myself, however at the end of the oral sex I realized he had cut my foreskin with his teeth, with a few tears, from being so ruff. (thebody.com)
  • Oral sex carries the lowest risk of HIV transmission . (thebody.com)
  • 2. I agree with our friend, again oral sex carries the lowest risk. (thebody.com)
  • Women in whom C. albicans was detected were more likely to report use of tampons, engage in receptive oral sex, and use of over-the-counter (OTC) antifungals to self-treat for vaginal infections before seeing a doctor for examination. (contemporaryobgyn.net)
  • However, using the same model, antifungal use and receptive oral sex were significantly associated with C. albicans detection, with a dose-response trend for increasing frequency of oral sex and escalating odds of C. albicans detection. (contemporaryobgyn.net)
  • They also point to receptive oral sex as a risk factor for C. albicans colonization. (contemporaryobgyn.net)
  • The implications of physical and biological sex differences on sex role behavior cannot be understood without analyzing the complementary role of the sociocultural meaning of sex roles. (ed.gov)
  • Research indicates that lower class children define masculine and feminine characteristics and roles as sharply different while the middle class displays more mutuality in sex role interchange. (ed.gov)
  • Kuhn's research has revealed that different brain types use dopamine differently, strongly suggesting that factors such as sex and age can play significant roles in addiction. (aaas.org)
  • Sex Roles, V ol. (deepdyve.com)
  • Field data collected in Ciudad Juarez on the price of sex with and without a condom for the same FSW respondent allowed calculation of the price premium for unprotected sex based on these paired prices, holding unobservable characteristics constant. (ssrn.com)
  • Overall, 37% (95% CI = 32-43%) of MSM reported using a condom at last sex, and 34% (95% CI = 28-39%) reported being tested for HIV in the past year. (unboundmedicine.com)
  • Individual counseling and education interventions should focus on increasing condom use and encouraging safer sex practices among all sexually active MSM, particularly those groups with low levels of condom use and multiple sex partners. (unboundmedicine.com)
  • Being aged 26 years or older, being in debt, and alcohol use were factors associated with inconsistent condom use across partner types. (biomedcentral.com)
  • In addition to enhancing interventions that focus on individual level risk reduction, it is important to undertake structural interventions that promote social acceptance of same-sex sexuality and address contextual barriers to condom use such as alcohol use. (biomedcentral.com)
  • To date, only adults have been studied for substance use disorders with regards to a particular genetic risk factor. (eurekalert.org)
  • The work is some of the first to look for genetic markers of risk in relation to adolescent brain development and how these factors relate to risk of future substance use disorders. (eurekalert.org)
  • Instead, the team found that autism risk is associated with genetic variants that are known to contribute differently to physical traits such as height, weight, BMI, and waist and hip measurements in men and women, suggesting that their effects on autism risk might differ between the sexes, as well. (ucsf.edu)
  • AIM: This study aimed to test the hypothesis that common genetic factors can explain the association between measures of sex typicality, mating success, and homosexuality in a Western (British) sample of female twins. (uzh.ch)
  • Multivariate twin modeling showed that common genetic factors explained the relationship between sexual orientation, sex typicality, and mating success through a shared latent factor. (uzh.ch)
  • CONCLUSIONS: Our findings suggest that genetic factors responsible for nonheterosexuality are shared with genetic factors responsible for the number of lifetime sexual partners via a latent sex typicality phenotype in human females. (uzh.ch)
  • Women with diabetes may be subject to even more adverse changes in coagulation, vascular function, and CHD risk factor levels than diabetic men ( 10 - 13 ). (diabetesjournals.org)
  • Data from the 2005 through 2008 Oregon Behavioral Risk Factor Surveillance System were used to examine associations between sexual orientation and chronic conditions, health limitations, health risk factors, and protective health practices. (cdc.gov)
  • To understand the health of LGB adults in Oregon, the Oregon Public Health Division added a consistent sexual orientation question to the state's Behavioral Risk Factor Surveillance System (BRFSS) survey in 2005. (cdc.gov)
  • Although previous studies investigating risk factors for recurrence of localized melanomas could not prove male sex as a risk factor, we showed that sex was an important risk factor for predicting recurrence, even in localized melanomas," Oh and colleagues wrote. (healio.com)
  • Moreover, complete evaluation of apparently lower risk factor along with concomitant clinical conditions in AF patients appears mandatory, particularly for female patients, in order to achieve the most appropriate anticoagulant treatment, either in male or in female patients. (hindawi.com)
  • A wealth of accumulating data indicates that type 2 diabetes, too, is a much stronger risk factor for cardiovascular diseases in women than in men. (mdedge.com)
  • Conclusion Further research is needed to understand the high rate of payment for sex in this population, which appears to be a major risk factor for STI including HIV. (bmj.com)
  • Polytomous logistic regressions were used in estimating respective ORs of IVF and BV, in relation to each potential risk factor. (bmj.com)
  • Conclusions Smoking is a major risk factor for incident AAA, with a strong and similar association between men and women. (bmj.com)
  • CONCLUSIONS: In men and women, most variables predicting future diabetes in the present study are also known to be important risk factors for cardiovascular disease and arteriosclerosis. (diabetesincontrol.com)
  • Other diseases, such as cardiovascular disease, can simply look very different in men and women, and the two sexes are also known to respond differently to certain drugs, making sex differences a crucial factor for doctors to take into account in diagnosis and treatment. (ucsf.edu)
  • SNOWMASS, COLO. - Achieving continued reductions in cardiovascular deaths in U.S. women will require that physicians make greater use of sex-specific risk factors that aren't incorporated in the ACC/AHA atherosclerotic cardiovascular disease risk score , Dr. Jennifer H. Mieres asserted at the Annual Cardiovascular Conference at Snowmass. (mdedge.com)
  • INNSBRUCK, Austria-"Cardiovascular disease is not a man's disease," and while it may seem like trends are headed in the right direction for women, more work still could be done, according to Imo Hoefer, MD, PhD (University Medical Center Utrecht, the Netherlands), who chaired a session on sex differences at the 2016 European Atherosclerosis Society Congress. (tctmd.com)
  • In another presentation, Børge Nordestgaard, MD (University of Copenhagen) focused on the role of sex-specific risk factors in cardiovascular disease. (tctmd.com)
  • Bringing these risk factors under control could prevent millions of untimely deaths not only from cardiovascular disease, but also from diabetes, cancer, and chronic obstructive pulmonary disease, he estimated. (tctmd.com)
  • It is believed that social media is used in over 90% of minor-related sex trafficking cases to access and groom the victim. (voiceamerica.com)
  • It is also believed that one out of six youth, who runaway from home, will be victims of sex trafficking in the first 48 hours. (voiceamerica.com)
  • Opal is the President and CEO of Million Kids, a non-profit organization dedicated to eradicating child sex trafficking. (voiceamerica.com)
  • Coakley, Norfolk County District Attorney Michael Morrissey of Quincy and other prosecutors are pushing for passage of a bill that would make human trafficking a crime in Massachusetts and create harsher penalties for pimps who sell adults and adolescents for labor and sex. (patriotledger.com)
  • Human trafficking hit home in May when a 28-year-old Boston man was charged with kidnapping a 15-year-old girl at an MBTA stop and forcing her to have sex with men at motel rooms, including the Best Western Adams Inn in Quincy. (patriotledger.com)
  • The topic of sex trafficking has taken the nation by storm in recent years. (wifostercareandadoption.org)
  • Blackwell must serve a minimum term of nine years and was put on the sex offenders' register for life, as well as being ordered not to directly or indirectly contact any of his victims. (yahoo.com)
  • Greenfeld LA. Sex offenses and offenders: an analysis of data on rape and sexual assault. (wikipedia.org)
  • and the histological structure for OT neurons is sexually dimorphic, suggesting that sex steroids play a role in early morphogenesis of this system ( de Vries, 2008 ). (frontiersin.org)
  • Several studies of patients without diabetes have demonstrated disparities in treatment of heart disease and CHD risk factors among women and men in primary care ( 14 , 15 ) and hospital settings ( 16 , 17 ). (diabetesjournals.org)
  • It is inconceivable that Congress, in an Act the primary purpose of which was to eliminate long-existing "endemic" sex-based wage disparities, would create an exception for basing new hires' salaries on these very disparities - disparities that Congress declared are not only related to sex but caused by sex. (jacksonlewis.com)
  • Conclusions Frequency of sex has declined recently in Britain, more markedly among those in early middle age and those who are married or cohabiting. (bmj.com)
  • Conclusions: A substantial sex-related difference in intact FGF23 concentration exists during early infancy, possibly related to differences in skeletal growth between boys and girls. (diva-portal.org)
  • Age adjusted odds ratios showed that men and women in better physical and mental health had sex more frequently, as did those who were fully employed and those with higher earnings. (bmj.com)
  • Sex-specific hazard ratios (HRs) were estimated from Cox proportional hazard models. (diabetesincontrol.com)
  • In the two new studies, Weiss and her team analyzed genome-wide association study (GWAS) data* to search for patterns that might support or rule out competing hypotheses about the origins of sex differences in a number of diseases, and compared these patterns with those associated with physical traits that obviously differ between the sexes, such as height, body mass index (BMI), and waist-to-hip ratios. (ucsf.edu)
  • However, at the regional level, Bangladesh is characterised by an east-west divide in sex ratios at birth. (www.gov.uk)
  • While the western region shows normal sex ratios at birth, the eastern region displays distorted sex ratios. (www.gov.uk)
  • There is a need for further research covering several other pockets that have distorted sex ratios at birth. (www.gov.uk)
  • Of the adiposity variables, visceral adipose tissue (VAT) correlated more strongly with the risk factors for MI than did body mass index (BMI), total adipose tissue (TAT), subcutaneous adipose tissue (SCAT), waist-to-hip ratio (WHR), and waist circumference (W). Controlling for VAT eliminated all of the other adiposity correlations that had been significant. (nih.gov)
  • Coronary heart disease risk factors in women with polycystic ovary syndrome. (medscape.com)
  • Jennifer R. Berman, MD, is co-author of the national bestsellers "For Women Only: A Revolutionary Guide to Overcoming Sexual Dysfunction and Reclaiming Your Sex Life" and "Secrets of the Sexually-Satisfied Woman. (voiceamerica.com)
  • Drs. Bartnof and Berman will discuss factors that contribute to women's libido and how it may be restored in women with libido decline. (voiceamerica.com)
  • The proportion reporting no sex in the past month fell between Natsal-1 and Natsal-2 (from 28.5% to 23.0% in women and from 30.9% to 26.0% in men) but increased significantly in Natsal-3 (to 29.3% in women and 29.2% in men). (bmj.com)
  • The proportion reporting sex 10 times or more in the past month increased between Natsal-1 and Natsal-2, from 18.4% to 20.6% in women and from 19.9% to 20.2% in men, but fell in Natsal-3, to 13.2% in woman and 14.4% in men. (bmj.com)
  • Several high income countries have recently reported a decline in the frequency with which men and women have sex. (bmj.com)
  • Research indicates that men and women who enjoy an active sex life are fitter, happier, 6 7 and have better cognitive function 8 and increased life expectancy. (bmj.com)
  • West Midlands Police said that in each instance, young women were walking alone early in the morning when they were attacked from behind and either raped or subjected to other sex crimes. (yahoo.com)
  • The film clip includes a same-sex marriage proposal between two women. (perthnow.com.au)
  • Men are from Mars and women are from Venus: Sex differences in insulin action and secretion. (indigo.ca)
  • Sex differences have been found in von Willebrand factor concentration, which is higher in women compared to males [ 5 ]. (hindawi.com)
  • One of the keys to further reductions in women is more widespread physician evaluation of sex-specific risk factors - such as a history of elevated blood pressure in pregnancy, polycystic ovarian syndrome, or radiation therapy for breast cancer - as part of routine cardiovascular risk assessment in women, said Dr. Mieres, senior vice president office of community and public health at Hofstra Northwell in Hempstead, N.Y. (mdedge.com)
  • In addition to the growing appreciation that it's important to consider sex-specific cardiovascular risk factors, recent evidence shows that many of the traditional risk factors are stronger predictors of ischemic heart disease in women than men. (mdedge.com)
  • A nationwide Swedish case-control study of 388 men and 63 women with adenocarcinoma of the oesophagus and gastro-oesophageal function and 676 men controls and 140 women investigated whether sex differences in aetiology contribute to male predominance. (pubmedcentralcanada.ca)
  • We hypothesised that male predominance in oesophageal adenocarcinoma is due atleast to established risk factors having a more harmful effect on men than women and that protective factors have a stronger preventive effect on women than men. (pubmedcentralcanada.ca)
  • 3. Causes neediness in men and women - thus at root of sex and love addictions. (psychcentral.com)
  • To understand the factors that contribute to regional variations in the sex ratio at birth, primary research has been conducted that comprised a household survey among married women aged 18-49 years who had at least two living children, the youngest of which was aged 0-5. (www.gov.uk)
  • In Comilla, the sex of living children had an effect on its desire of women for more children and use of contraception. (www.gov.uk)
  • However, women were less likely than men to have treated and controlled dyslipidaemia (21% vs 28% for treatment and 15% vs 24% for control, for women versus men in 2017).Important sex differences persist in cardiovascular risk factors in England, with an overall higher number of risk factors in men than in women. (onmedica.com)
  • In medical school, many physicians aren't formally trained to ask women about their sex drive. (multicare.org)
  • Here are a few of the factors that can affect sexual drive in women. (multicare.org)
  • About 8% (126/1 594) of women, 33% (22/75) of men, and 25% (12/50) of transgender people had unprotected sex. (scielo.org.za)
  • [3,4,In a 2004 - 2005 Durban study, 775 women at high risk for HIV infection - 78.8% of whom self-identified as sex workers - were screened, and 59.6% were found to be HIV-positive. (scielo.org.za)
  • Tubal factor is one complication of Chlamydia trachomatis infection in women. (wikipedia.org)
  • In Zimbabwe, women who were working were much more likely to report forced sex by a spouse than those who were not. (wikipedia.org)
  • Poverty forces many women and girls into occupations that carry a relatively high risk of sexual violence, particularly sex work. (wikipedia.org)
  • Risk factors for rape, physical assault, and post-traumatic stress disorder in women: examination of differential multivariate relationships. (wikipedia.org)
  • Socioeconomic differences were controlled for an examination of longitudinal data on established critical factors in career salience of female college graduates. (ed.gov)
  • Methods We calculated age-adjusted AAA incidence rates (IR) among 18 782 participants aged ≥65 years in the Southern Community Cohort Study who received Medicare coverage from 1999-2012, and assessed predictors of AAA using multivariable Cox proportional hazards models, overall and stratified by sex, adjusting for demographic, lifestyle, socioeconomic, medical and other factors. (bmj.com)
  • This study examined factors associated with satisfaction or regret following sex reassignment surgery (SRS) in 232 male-to-female transsexuals operated on between 1994 and 2000 by one surgeon using a consistent technique. (springer.com)
  • A new method for clitoroplasty in male-to-female sex reassignment surgery. (springer.com)
  • Female sex is recognized as an independent predictor of thromboembolic risk, particularly in older patients. (hindawi.com)
  • Besides, no anticoagulation is indicated for AF female patients without other risk factors. (hindawi.com)
  • Nationally, the sex ratio at birth in Bangladesh has persisted at its natural level of 105 male per 100 female newborns for the past half century. (www.gov.uk)
  • Further, we compared two different strains of mice with differential susceptibility to XY male-to-female sex reversal. (duke.edu)
  • Prior salary alone or in combination with other factors cannot justify a wage differential between male and female employees under the Equal Pay Act, the U.S. Court of Appeals for the Ninth Circuit has held in an en banc decision. (jacksonlewis.com)
  • Tubal factor infertility (TFI) is female infertility caused by diseases, obstructions, damage, scarring, congenital malformations or other factors which impede the descent of a fertilized or unfertilized ovum into the uterus through the Fallopian tubes and prevents a normal pregnancy and full term birth. (wikipedia.org)
  • It depends upon the book, the characters, the inter-play of relationships which adds to the dimension of sex or loving making. (hindustantimes.com)
  • This information complements other available parent resources by emphasizing the importance of talking with teens about sex and healthy relationships. (cdc.gov)
  • Talking with teens about sex-related topics, including healthy relationships and the prevention of HIV, other sexually transmitted diseases (STDs), and pregnancy, is a positive parenting practice that has been widely researched. (cdc.gov)
  • When parents communicate honestly and openly with their teenage son or daughter about sex, relationships, and the prevention of HIV, STDs, and pregnancy, they can help promote their teen's health and reduce the chances that their teen will engage in behaviors that place them at risk. (cdc.gov)
  • Talking about sex, relationships, and the prevention of HIV, STDs, and pregnancy may not always be comfortable or easy, but you can encourage your teen to ask you questions and be prepared to give fair and honest answers. (cdc.gov)
  • Overlapping recruitment among 273 male sex workers and 290 other MSM was common. (popcouncil.org)
  • Male sex workers were also more likely to be HIV infected (26.3% versus 12.2%, P = 0.007). (popcouncil.org)
  • 'X Factor' girl group 4th Impact have revealed that they won't be letting any of their male contestants turn their heads during this year's competition, as they've all taken a vow of chastity. (huffingtonpost.co.uk)
  • This analysis revealed that in the C57BL/6J strain, the male pathway is delayed by ~5 hours, likely explaining the increased susceptibility to sex reversal in this strain. (duke.edu)
  • The employer defended the motion for summary judgment on the basis that it had used "factors other than sex" in deciding to pay plaintiff's male replacement more than it had paid plaintiff. (jdsupra.com)
  • The musical reality series, in its third season, has been having problems with its contestants violating its no-sex regulation and series executives have decided to assign repercussions to such actions including expulsion from the series competition, The Sun reported. (upi.com)
  • Sex differences in leptin regulation of cardiovascular function in health and metabolic diseases. (indigo.ca)
  • Sex effects at the ramparts: Nutrient- and microbe-mediated regulation of the immune-metabolic interface. (indigo.ca)
  • Thus, regulation of the Vegfa gene to produce angiogenic or anti-angiogenic isoforms may be a mechanism to alter sex-specific vascular development, formation of seminiferous cords, and/or follicle progression within mammalian gonads. (unl.edu)
  • Despite a long history of existence of people with diverse sexualities in India [ 8 , 9 ] open discussions about same-sex sexuality in the public domain are still limited. (biomedcentral.com)
  • HIV/AIDS surveillance data were used to determine the number of living males reporting a history of sex with men who had been diagnosed in NYC with HIV infection through 2002 (23% of HIV-infected males did not have HIV transmission risk information available). (unboundmedicine.com)
  • For the condition factor, the sinusoidal equation returned significant seasonal variation in both raw data (P=0.02) and with mean values (P=0.00) for males, but only with raw data for females (P=0.04), which appears to reflect variation in the energy budget between genders. (scielo.br)
  • With regard to the sex ratio, more reproductive females were captured than males in January and March, 2009, which suggests a pattern of segregation related to the reproductive process. (scielo.br)
  • In national surveys conducted by The National Campaign to Prevent Teen and Unplanned Pregnancy, teens report that their parents have the greatest influence over their decisions about sex-more than friends, siblings, or the media. (cdc.gov)
  • Although you may know that having "the talk" with your teen about sex and HIV, STD, and pregnancy prevention is important, having a series of discussions that begin early, happen often, and continue over time can make more of a difference than a single conversation. (cdc.gov)
  • This week we examine the "push-pull" influencing factors that make runaway youth so vulnerable. (voiceamerica.com)
  • Objectives To examine changes over time in the reported frequency of occurrence of sex and associations between sexual frequency and selected variables. (bmj.com)
  • Methods In this cross-sectional study, we recruited through peer referral men aged between 18 and 60 years, who reported sex with men at least once in the 12 months prior to the survey. (bmj.com)
  • In addition, the association between vaginal flora abnormalities and factors such as younger age, HIV, gonorrhoea trichomoniasis and candidiasis were modified by the study site (all p for interaction ≤0.05). (bmj.com)
  • The relationship between some factors and vaginal flora abnormalities may be site-specific. (bmj.com)
  • Multivariate polytomous analysis of IVF and BV showed that they were generally associated with the same factors. (bmj.com)
  • A single-nucleotide polymorphism (C/A) located within an E-box at the −20 position of the human angiotensinogen (AGT) promoter may regulate transcriptional activation through differential recruitment of the transcription factors upstream stimulatory factor (USF) 1 and 2. (ahajournals.org)
  • Most federal courts- but not all- have interpreted the EPA's "factor other than sex" defense to require an employer to show that the pay differential is consistent with a legitimate business purpose. (jdsupra.com)
  • This decision overturns the 2017 decision of a three-judge panel of the Ninth Circuit and the Court's 1982 decision holding that prior salary was a permissible "factor other than sex" under the Equal Pay Act. (jacksonlewis.com)
  • Bae HR, Hodge DL, Yang GX, Leung PSC, Chodisetti SB, Valencia JC, Sanford M et al (2018) The interplay of type I and type II interferons in murine autoimmune cholangitis as a basis for sex-biased autoimmunity. (springer.com)
  • This condition can affect the sex life of many couples and is a real cause for concern. (articlesfactory.com)
  • Until marriage for all became the law of the land in 2015, most same-sex couples couldn't make their union officially legal, which meant they didn't face some of the same financial concerns as married heterosexual couples. (nerdwallet.com)
  • A determination of predisposing factors that contribute to reward seeking may eventually help us to identify novel targets for intervention to ensure this tendency does not result in drug taking and other high risk behaviors," said Diana Fishbein, PhD, professor of human development and family studies at Penn State and co-principal investigator of the study. (eurekalert.org)
  • Is the Subject Area "Sex determination" applicable to this article? (plos.org)
  • Further, we applied these approaches to uncover the TFs important in mammalian sex determination. (duke.edu)
  • Further, we conducted motif analysis to reveal novel regulators of sex determination. (duke.edu)