A species of gram-negative, facultatively anaerobic, rod-shaped bacteria found in soil, water, food, and clinical specimens. It is a prominent opportunistic pathogen for hospitalized patients.
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in the natural environment (soil, water, and plant surfaces) or as an opportunistic human pathogen.
Infections with bacteria of the genus SERRATIA.
4-Methoxy-5-((5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl)- 2,2'-bi-1H-pyrrole. A toxic, bright red tripyrrole pigment from Serratia marcescens and others. It has antibacterial, anticoccidial, antimalarial, and antifungal activities, but is used mainly as a biochemical tool.
Infections with bacteria of the family ENTEROBACTERIACEAE.
A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.
Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.
Substances that reduce the growth or reproduction of BACTERIA.
Proteins found in any species of bacterium.
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
A linear polysaccharide of beta-1->4 linked units of ACETYLGLUCOSAMINE. It is the second most abundant biopolymer on earth, found especially in INSECTS and FUNGI. When deacetylated it is called CHITOSAN.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.
A species of gram-negative bacteria in the genus SERRATIA found in plants and the DIGESTIVE TRACT of rodents. It is the most prevalent Serratia species in the natural environment.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Any infection which a patient contracts in a health-care institution.
An enzyme that catalyzes the reduction of aspartic beta-semialdehyde to homoserine, which is the branch point in biosynthesis of methionine, lysine, threonine and leucine from aspartic acid. EC 1.1.1.3.
A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Substances elaborated by specific strains of bacteria that are lethal against other strains of the same or related species. They are protein or lipopolysaccharide-protein complexes used in taxonomy studies of bacteria.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The functional hereditary units of BACTERIA.
Any normal or abnormal coloring matter in PLANTS; ANIMALS or micro-organisms.
An enzyme that catalyzes the formation of beta-aspartyl phosphate from aspartic acid and ATP. Threonine serves as an allosteric regulator of this enzyme to control the biosynthetic pathway from aspartic acid to threonine. EC 2.7.2.4.
Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS.
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
Techniques used in studying bacteria.
A membrane or barrier with micrometer sized pores used for separation purification processes.
A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The act of cleansing the hands with water or other liquid, with or without the inclusion of soap or other detergent, for the purpose of destroying infectious microorganisms.
Provision of physical and biological barriers to the dissemination of potentially hazardous biologically active agents (bacteria, viruses, recombinant DNA, etc.). Physical containment involves the use of special equipment, facilities, and procedures to prevent the escape of the agent. Biological containment includes use of immune personnel and the selection of agents and hosts that will minimize the risk should the agent escape the containment facility.
A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Congenital structural abnormalities of the LOWER EXTREMITY.
The separation of particles from a suspension by passage through a filter with very fine pores. In ultrafiltration the separation is accomplished by convective transport; in DIALYSIS separation relies instead upon differential diffusion. Ultrafiltration occurs naturally and is a laboratory procedure. Artificial ultrafiltration of the blood is referred to as HEMOFILTRATION or HEMODIAFILTRATION (if combined with HEMODIALYSIS).
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Electron microscopy in which the ELECTRONS or their reaction products that pass down through the specimen are imaged below the plane of the specimen.
Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.

Fatal Serratia marcescens meningitis and myocarditis in a patient with an indwelling urinary catheter. (1/1084)

Serratia marcescens is commonly isolated from the urine of patients with an indwelling urinary catheter and in the absence of symptoms is often regarded as a contaminant. A case of fatal Serratia marcescens septicaemia with meningitis, brain abscesses, and myocarditis discovered at necropsy is described. The patient was an 83 year old man with an indwelling urinary catheter who suffered from several chronic medical conditions and from whose urine Serratia marcescens was isolated at the time of catheterisation. Serratia marcescens can be a virulent pathogen in particular groups of patients and when assessing its significance in catheter urine specimens, consideration should be given to recognised risk factors such as old age, previous antibiotic treatment, and underlying chronic or debilitating disease, even in the absence of clinical symptoms.  (+info)

Genetic analysis of the Serratia marcescens N28b O4 antigen gene cluster. (2/1084)

The Serratia marcescens N28b wbbL gene has been shown to complement the rfb-50 mutation of Escherichia coli K-12 derivatives, and a wbbL mutant has been shown to be impaired in O4-antigen biosynthesis (X. Rubires, F. Saigi, N. Pique, N. Climent, S. Merino, S. Alberti, J. M. Tomas, and M. Regue, J. Bacteriol. 179:7581-7586, 1997). We analyzed a recombinant cosmid containing the wbbL gene by subcloning and determination of O-antigen production phenotype in E. coli DH5alpha by sodium dodecyl sulfate-polyacrylamide electrophoresis and Western blot experiments with S. marcescens O4 antiserum. The results obtained showed that a recombinant plasmid (pSUB6) containing about 10 kb of DNA insert was enough to induce O4-antigen biosynthesis. The same results were obtained when an E. coli K-12 strain with a deletion of the wb cluster was used, suggesting that the O4 wb cluster is located in pSUB6. No O4 antigen was produced when plasmid pSUB6 was introduced in a wecA mutant E. coli strain, suggesting that O4-antigen production is wecA dependent. Nucleotide sequence determination of the whole insert in plasmid pSUB6 showed seven open reading frames (ORFs). On the basis of protein similarity analysis of the ORF-encoded proteins and analysis of the S. marcescens N28b wbbA insertion mutant and wzm-wzt deletion mutant, we suggest that the O4 wb cluster codes for two dTDP-rhamnose biosynthetic enzymes (RmlDC), a rhamnosyltransferase (WbbL), a two-component ATP-binding-cassette-type export system (Wzm Wzt), and a putative glycosyltransferase (WbbA). A sequence showing DNA homology to insertion element IS4 was found downstream from the last gene in the cluster (wbbA), suggesting that an IS4-like element could have been involved in the acquisition of the O4 wb cluster.  (+info)

Strain-dependent cytotoxic effects of endotoxin for mouse peritoneal macrophages. (3/1084)

The cytotoxic effects of bacterial lipopolysaccharides (LPS) on mouse leukocytes have been examined in vivo and in vitro. Intraperitoneal injection of LPS into C57BL/6 mice greatly reduced the recovery of mononuclear cells; LPS was cytotoxic for macrophages, but had a mitogenic effect on lymphocytes. Similar effects of LPS on peritoneal leukocytes were observed in vitro. When monolayers of adherent peritoneal cells were studied in vitro, cytotoxicity was also observed, suggesting that the effect of LPS on macrophages is direct and does not require participation by lymphocytes. Entirely different results were obtained when peritoneal macrophages from LPS-resistant C3H/HeJ mice were studied. LPS failed to activate lymphocytes and was not cytotoxic for macrophages in vitro or in vivo. The effect of LPS on polymorphonuclear leukocytes appeared to be the same in all mouse stains studied. Lipid A was shown to be the most biologically active portion of the LPS molecule. Whereas polysaccharide-deficient endotoxins extracted from rough mutants of Salmonella typhimurium were cytotoxic for macrophages in vitro, polysaccharides that lacked esterified fatty acids did not exhibit this activity. Since LPS may mediate its effects through affinity for mammalian cell membranes, the cellular unresponsiveness of C3H/H3J mice to LPS may reflect an inability of cells from LPS-resistant strains to interact with LPS at the membrane level.  (+info)

NMR studies of the C-terminal secretion signal of the haem-binding protein, HasA. (4/1084)

HasA is a haem-binding protein which is secreted under iron-deficiency conditions by the gram-negative bacterium Serratia marcescens. It is a monomer of 19 kDa (187 residues) able to bind free haem as well as to capture it from haemoglobin. HasA delivers haem to a specific outer-membrane receptor HasR and allows the bacteria to grow in the absence of any other source of iron. It is secreted by a signal peptide-independent pathway which involves a C-terminal secretion signal and an ABC (ATP-binding cassette) transporter. The C-terminal region of the secretion signal containing the essential secretion motif is cleaved during or after the secretion process by proteases secreted by the bacteria. In this work, we study by 1H NMR the conformation of the C-terminal extremity of HasA in the whole protein and that of the isolated secretion signal peptide in a zwitterionic micelle complex that mimicks the membrane environment. We identify a helical region followed by a random-coil C-terminus in the peptide-micelle complex and we show that in both the whole protein and the complex, the last 15 residues containing the motif essential for secretion are highly flexible and unstructured. This flexibility may be a prerequisite to the recognition of HasA by its ABC transporter. We determine the cleavage site of the C-terminal extremity of the protein and analyse the effect of the cleavage on the haem acquisition process.  (+info)

Use of microdilution panels with and without beta-lactamase inhibitors as a phenotypic test for beta-lactamase production among Escherichia coli, Klebsiella spp., Enterobacter spp., Citrobacter freundii, and Serratia marcescens. (5/1084)

Over the past decade, a number of new beta-lactamases have appeared in clinical isolates of Enterobacteriaceae that, unlike their predecessors, do not confer beta-lactam resistance that is readily detected in routine antibiotic susceptibility tests. Because optimal methodologies are needed to detect these important new beta-lactamases, a study was designed to evaluate the ability of a panel of various beta-lactam antibiotics tested alone and in combination with beta-lactamase inhibitors to discriminate between the production of extended-spectrum beta-lactamases, AmpC beta-lactamases, high levels of K1 beta-lactamase, and other beta-lactamases in 141 isolates of Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, Enterobacter aerogenes, Citrobacter freundii, and Serratia marcescens possessing well-characterized beta-lactamases. The microdilution panels studied contained aztreonam, cefpodoxime, ceftazidime, cefotaxime, and ceftriaxone, with and without 1, 2, and 4 microg of clavulanate per ml or 8 microg of sulbactam per ml and cefoxitin and cefotetan with and without 8 microg of sulbactam per ml. The results indicated that a minimum panel of five tests would provide maximum separation of extended-spectrum beta-lactamase high AmpC, high K1, and other beta-lactamase production in Enterobacteriaceae. These included cefpodoxime, cefpodoxime plus 4 microg of clavulanate per ml, ceftazidime, ceftriaxone, and ceftriaxone plus 8 microg of sulbactam per ml. Ceftriaxone plus 2 microg of clavulanate per ml could be substituted for cefpodoxime plus 4 microg of clavulanate per ml without altering the accuracy of the tests. This study indicated that tests with key beta-lactam drugs, alone and in combination with beta-lactamase inhibitors, could provide a convenient approach to the detection of a variety of beta-lactamases in members of the family Enterobacteriaceae.  (+info)

Dry-heat destruction of lipopolysaccharide: dry-heat destruction kinetics. (6/1084)

Dry-heat destruction kinetics of lipopolysaccharides from Escherichia coli, Serratia marcescens, and Salmonella typhosa at 170 to 250 degrees C are described. The destruction rate seems to follow the second order and can be linearized by the equation, log y = a + b . -10cx. Because c is the slope, 1/c = D3. Both a and b are constant at a given temperature and are linear functions of temperature. The D(3)170, D(3)190, D(3)210, D(3)230, and D(3)250 values for E. coli lipopolysaccharide are 251, 99.4, 33.3, 12.3, and 4.99 min, respectively, with a z value of 46.4 min. The D values for lipopolysaccharides from S. marcescens and S. typhosa are not significantly different from those from E. coli lipopolysaccharide.  (+info)

The NucE and NucD lysis proteins are not essential for secretion of the Serratia marcescens extracellular nuclease. (7/1084)

The nuclease of Serratia marcescens is an extracellular protein encoded by the nucA gene. Pre-nuclease carries a typical 21-amino-acid N-terminal signal sequence that interacts with the Sec machinery to allow the translocation of nuclease to the periplasm. In Escherichia coli the nuclease remains in the periplasm; however, S. marcescens has the capacity to secrete nuclease extracellularly. The nucC operon carrying the nucEDC genes of S. marcescens has been identified previously. NucC is a transcriptional activator necessary for expression of nuclease as well as the extracellular bacteriocin 28b. NucE resembles and can act as a bacteriophage holin, whereas NucD has homology to bacteriophage lysozyme-like proteins. When present on a multicopy plasmid, the nucC operon, and specifically the nucED genes, appeared to allow extracellular secretion of nuclease from E. coli. Here experiments are reported which demonstrate that, when the nucC operon was placed in the E. coli chromosome in single copy, nuclease secretion was lost and nuclease remained periplasmic. The converse experiment, deletion of the nucE and nucD genes from the chromosome of S. marcescens, likewise had no effect on nuclease secretion by S. marcescens. It is concluded therefore that NucD and NucE are not necessary for nuclease secretion.  (+info)

Characterization of a dam mutant of Serratia marcescens and nucleotide sequence of the dam region. (8/1084)

The DNA of Serratia marcescens has N6-adenine methylation in GATC sequences. Among 2-aminopurine-sensitive mutants isolated from S. marcescens Sr41, one was identified which lacked GATC methylation. The mutant showed up to 30-fold increased spontaneous mutability and enhanced mutability after treatment with 2-aminopurine, ethyl methanesulfonate, or UV light. The gene (dam) coding for the adenine methyltransferase (Dam enzyme) of S. marcescens was identified on a gene bank plasmid which alleviated the 2-aminopurine sensitivity and the higher mutability of a dam-13::Tn9 mutant of Escherichia coli. Nucleotide sequencing revealed that the deduced amino acid sequence of Dam (270 amino acids; molecular mass, 31.3 kDa) has 72% identity to the Dam enzyme of E. coli. The dam gene is located between flanking genes which are similar to those found to the sides of the E. coli dam gene. The results of complementation studies indicated that like Dam of E. coli and unlike Dam of Vibrio cholerae, the Dam enzyme of S. marcescens plays an important role in mutation avoidance by allowing the mismatch repair enzymes to discriminate between the parental and newly synthesized strands during correction of replication errors.  (+info)

An exploration of the unique role that the red pigmented bacterium Serratia marcescens has played in merging the practices of both and art and science Various images of cultures of the bacterium Serratia marcescens Some history first Amongst microbiologists, the bacterium Serratia marcescens is especially noteworthy because of its production of the bright…
Serratia marcescens ATCC ® 27137D-5™ Designation: Genomic DNA from Serratia marcescens strain CDC 3100-71 TypeStrain=False Application:
Serratia marcescens culture. Petri dish containing a nutrient medium that has been used to culture the bacterium Serratia marcescens. This is a facultative anaerobic gram-negative rod bacterium. The red pigment it produces has been used in research to track bacterial activity. This bacterium is found in water, soil, animal and plants. The diseases it causes include sepsis, meningitis, urinary tract infections, osteomyelits and endocarditis. - Stock Image C036/9185
TY - JOUR. T1 - Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC β-lactamase overproduction and outer membrane protein loss. AU - Suh, Borum. AU - Bae, Il Kwon. AU - Kim, Juwon. AU - Jeong, Seok Hoon. AU - Yong, Dongeun. AU - Lee, Kyungwon. PY - 2010/12/1. Y1 - 2010/12/1. N2 - The aim of this study was to investigate the mechanisms involved in the meropenem resistance of Serratia marcescens clinical isolates. Meropenem-resistant (MIC range, 16 to 32 μg/ml) S. marcescens isolates were recovered from nine patients in a tertiary hospital in Seoul, South Korea, from June to November 2005. All the isolates shared identical or similar (,85% similarity) SpeI macrorestriction patterns, indicating clonal spread. PCR experiments did not detect any carbapenemase in those isolates. They carried the blaCTX-M-22 gene located on a 150-kbp plasmid of the incompatibility group L/M; however, the addition of clavulanic acid exhibited few effects on meropenem MICs. Although ...
False-colour transmission electron micrograph (TEM) of the rod-shaped, gram-negative bacteria Serratia marcescens, showing the characteristic convex curve of the end walls displayed by the 2 bacteria at centre. Species of Serratia occur as commensal fauna in the intestinal mucous membranes of man & mammals. S. marcescens is occasionally pathogenic in humans, presenting in long term, chronically sick patients in whom they may cause septicaemia. Previous medical interest in Serratiasp. existed only because they were likely to be identified in areas where other potential pathogens were found, and needed to be isolated. Magnification: x12000 at 35mm, x24000 at 6x7cm. - Stock Image B220/0233
Serratiopeptidase is a proteolytic enzyme extensively used as an anti-inflammatory and analgesic drug. Present work reports a thermoactive serratiopeptidase from Serratia marcescens AD-W2, a soil isolate from the North-Western Himalayan region of India. The extracellular metalloprotease has been purified by a simple two-step procedure resulting in a specific activity of 20,492 Units/mg protein with 5.28-fold purification. The molecular mass of the metalloprotease, as determined by SDS-PAGE was ~ 51 kDa. The purified serratiopeptidase presented optimum activity at pH 9.0, temperature 50 °C and stability in wide pH and temperature range. Critical temperature of 50 °C confirmed the thermoactivity of the purified serratiopeptidase. The kinetic studies of the purified serratiopeptidase revealed Vmax and Km of 57,256 Units/mL and 1.57 mg/mL, respectively, for casein. The purified serratiopeptidase from S. marcescens AD-W2 was found to be 100% identical to serralysin from Serratia marcescens ATCC 21074/E-15.
Abstract : Serratia marcescens (S. marcescens) has become an important nosocomial pathogens and increased resistantisolates were reported. The current study evaluates the impact of an alternate energy medicine i.e. Mr. Trivedis biofield energytreatment on S. marcescens for changes in sensitivity pattern of antimicrobial, biochemical characteristics, and biotype number.S. marcescens cells were procured from MicroBioLogics Inc., USA in sealed pack bearing the American Type CultureCollection (ATCC 13880) number and divided into two groups, Group (Gr.) I: control and Gr. II: treated. Gr. II was furthersubdivided into two sub-groups, Gr. IIA and Gr. IIB. Gr. IIA was analyzed on day 10, while Gr. IIB was stored and analyzedon day 159 (Study I). After retreatment on day 159, the sample (Study II) was divided into three separate tubes as first, secondand third tube, which were analyzed on day 5, 10 and 15 respectively. All experimental parameters were studied using theautomated MicroScan Walk-Away® ...
TY - JOUR. T1 - Prostaglandins and thromboxane in the delayed phase of shock induced by Serratia marcescens endotoxin. AU - Parratt, J. R.. AU - Sharma, N.. AU - Zeitlin, I. J.. PY - 1984/5. Y1 - 1984/5. N2 - The cardiovascular and metabolic effects of an endotoxin derived from Serratia marcescens were examined in anaesthetized, spontaneously‐breathing cats. There was a marked initial elevation of right atrial pressure (the result of pulmonary vasoconstriction) and decreases in systemic arterial pressure and in arterial PO2. The delayed effects of endotoxin shock in this species (1-8 h) consisted of a reduced cardiac output and decreased urinary excretion. Blood pressure and myocardial contractility (assessed from measurement of left ventricular (LV) dP/dt and LV end‐diastolic pressure) were maintained throughout this phase. There was evidence of a metabolic (lactic) acidosis largely compensated by hyperventilation. Plasma levels (both arterial and mixed venous blood samples) of ...
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BioAssay record AID 1085057 submitted by ChEMBL: Antimicrobial activity against Serratia marcescens at 10 to 60 ug/disk by disk diffusion method.
Comparative investigations of the physiological and biochemical properties of strains of a bacterium isolated from alfalfa and designated Erwinia amylovora var. alfalfae and a test isolate of Serratia marcescens showed that they differ by production of pigments with different solubility properties and absorption spectra. Otherwise, the results of the biochemical tests for the two strains were similar. The guanine-plus-cytosine content of the DNA from the alfalfa strains ranged from 56.6 to 57.9 moles percent (thermal denaturation) compared to 56.6 for the isolate of S. marcescens. These data indicate that the Gram-negative, pink-pigment-producing bacterium associated with crown rot of alfalfa is a strain of S. marcescens.. ...
S. marcescens is credited with a long fanatical history dating back to antiquity, when, because of its ability to produce a red pigment it was described as having masqueraded as blood . Early in this century, this distinctive red pigmentation of S. marcescens, combined with an apparent low level of virulence, led to its use as a biological marker of infection. Consequently, S. marcescens was used in a number of classic bacterial transmission experiments, which led to improved understanding of the epidemiology of infection. Under more controversial settings, S. marcescens was also used by the US military in a series of biological warfare test experiments conducted on the general population . From 1960 onwards, however, non-pigmented isolates of S. marcescenspredominated over pigmented strains in the clinical setting and were increasingly implicated in healthcare-associated infection particularly among compromised patients ...
Spontaneous mutants resistant to fluoroquinolones were obtained by exposing Serratia marcescens NIMA (wild-type strain) to increasing concentrations of ciprofloxacin both in liquid and on solid media. Frequencies of mutation ranged from 10-7 to 10-9. Active expulsion of antibiotic was explored as a possible mechanism of resistance in mutants as well as changes in topoisomerase target genes. The role of extrusion mechanisms in determining the emergence of multidrug-resistant bacteria was also examined. Mutants resistant to high concentrations of fluoroquinolones had a single mutation in their gyrA QRDR sequences, whereas the moderate resistance in the rest of mutants was due to extrusion of the ...
TY - JOUR. T1 - Severe and Progressive Cellulitis Caused by Serratia marcescens Following a Dog Scratch. AU - Pithadia, Deeti J.. AU - Weathers, Erena N.. AU - Colombo, Rhonda E.. AU - Baer, Stephanie L.. PY - 2019/2/1. Y1 - 2019/2/1. N2 - Soft tissue infections occur in over 30% of patients with chemotherapy-induced neutropenia. Gram-positive bacterial infections predominate early in neutropenia, and likelihood of infection by resistant bacteria and fungi increases with prolonged neutropenia. Prior infections and exposures influence the risk of rare pathogens. A 55-year-old woman with chemotherapy-induced neutropenia was scratched on her forearm by a dog. She cleaned the wound with isopropanol and was treated empirically with amoxicillin-clavulanate. Over the next 4 days, she developed fever along with erythema, edema, and mild tenderness of the forearm without purulence or crepitus. She was hospitalized and received empiric treatment with intravenous vancomycin, piperacillin-tazobactam, ...
Serratia marcescens ATCC ® 14756™ Designation: PCI 1107 TypeStrain=False Application: Membrane filter testing Sterility assurance Testing antimicrobial agent Testing antimicrobial handwashing formulations Pharmaceutical and Personal Care
Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane FusionProtein and Nucleotide-Binding Domain
I am 64 years old and I found out in 06 when I got pneumonia and ended up in the hospital and had several including lung biopsys that I have Sarcoid disease. It seems like every winter or spring I end up very sick or even in the hospital with a bacterial infection. I have had pneumonia several times caused by a bacteria. It is usually caused by MRSA or Staph. This year I was blessed with an infection that started the 25th of January I ran a fever for three weeks had Bronchitis so of course coughed my head off. I was given 10 day of Levaquin at first then after a few days off of any antibiotic my family Dr. ordered a sputum which showed a growth of 1+WBC, 3+ Gram positive Cocci, Gram Negative Bacillus. or Staph and Serratia Marcescens. I went to ER before I got that sputum report because I was so sick which was no help at all the PA who saw me simply looked at a chest xray they took and never even listened to my chest. His diagnosis was Acute Bronchitis and he gave me a Z pack. The day I was ...
I am 64 years old and I found out in 06 when I got pneumonia and ended up in the hospital and had several including lung biopsys that I have Sarcoid disease. It seems like every winter or spring I end up very sick or even in the hospital with a bacterial infection. I have had pneumonia several times caused by a bacteria. It is usually caused by MRSA or Staph. This year I was blessed with an infection that started the 25th of January I ran a fever for three weeks had Bronchitis so of course coughed my head off. I was given 10 day of Levaquin at first then after a few days off of any antibiotic my family Dr. ordered a sputum which showed a growth of 1+WBC, 3+ Gram positive Cocci, Gram Negative Bacillus. or Staph and Serratia Marcescens. I went to ER before I got that sputum report because I was so sick which was no help at all the PA who saw me simply looked at a chest xray they took and never even listened to my chest. His diagnosis was Acute Bronchitis and he gave me a Z pack. The day I was ...
Genus and Species: Serratia marcescens WCF Domain: Prokaryote Optimal Growth Medium: Brain Heart Infusion Agar Optimal Growth Temperature: 25° C Package: Tube Biosafety Level: 1 Gram Stain: Gram-Negative Shape: Bacillus (rod-shaped)
A recent article in Smithsonian Magazine features the work of Zachary Copfer, a biologist and artist who creates portraits of legendary icons such as Pablo Picasso, Leonardo da Vinci and Albert Einstein. One thing that makes Copfers work unique is his medium of choice; he employs a type of bacteria known as serratia marcescens that [...]. ...
Enhanced alkaline catalase production by Serratia marcescens FZSF01: Enzyme purification, characterization, and recombinant expression
abstract = {Innate immunity represents the first line of defense in animals. We report a genome-wide in vivo Drosophila RNA interference screen to uncover genes involved in susceptibility or resistance to intestinal infection with the bacterium Serratia marcescens. We first employed whole-organism gene suppression, followed by tissue-specific silencing in gut epithelium or hemocytes to identify several hundred genes involved in intestinal antibacterial immunity. Among the pathways identified, we showed that the JAK-STAT signaling pathway controls host defense in the gut by regulating stem cell proliferation and thus epithelial cell homeostasis. Therefore, we revealed multiple genes involved in antibacterial defense and the regulation of innate immunity ...
abstract = {Innate immunity represents the first line of defense in animals. We report a genome-wide in vivo Drosophila RNA interference screen to uncover genes involved in susceptibility or resistance to intestinal infection with the bacterium Serratia marcescens. We first employed whole-organism gene suppression, followed by tissue-specific silencing in gut epithelium or hemocytes to identify several hundred genes involved in intestinal antibacterial immunity. Among the pathways identified, we showed that the JAK-STAT signaling pathway controls host defense in the gut by regulating stem cell proliferation and thus epithelial cell homeostasis. Therefore, we revealed multiple genes involved in antibacterial defense and the regulation of innate immunity ...
abstract = {Innate immunity represents the first line of defense in animals. We report a genome-wide in vivo Drosophila RNA interference screen to uncover genes involved in susceptibility or resistance to intestinal infection with the bacterium Serratia marcescens. We first employed whole-organism gene suppression, followed by tissue-specific silencing in gut epithelium or hemocytes to identify several hundred genes involved in intestinal antibacterial immunity. Among the pathways identified, we showed that the JAK-STAT signaling pathway controls host defense in the gut by regulating stem cell proliferation and thus epithelial cell homeostasis. Therefore, we revealed multiple genes involved in antibacterial defense and the regulation of innate immunity ...
An example of an infectious pathogen working across large evolutionary distances is the bacterium Serratia marcescens. It is found in a variety of animal species, and also can be found free-living in water and soil. Its transmission from human sewage has resulted in the decimation of Caribbean elkhorn coral.. The distance between humans and corals emphasizes the possibility that certain organisms may prove pathogenic across a wide evolutionary divide, Chyba writes. Of course, the evolutionary divide between humans and coral would not be as wide a gulf as between any martian organisms and human beings. Yet one theory for the origin of life on Earth is that it was transferred here from Mars by meteorites. This variant of the Panspermia theory suggests that life on Earth and any life on Mars might be closely related.. If Mars and Earth share the basis for life, this life would presumably have evolved well beyond the original form. Such a large evolutionary divide could provide protection from ...
North Carolina manufacturer AM2 Pat Inc. has recalled all lots and sizes of its syringes prefilled with Heparin or saline, after discovering that they may be contaminated with the bacteria Serratia marcescens.
Blood and urine samples were obtained for culture in the emergency room and therapy with intravenous levofloxacin (500 mg twice a day for two days, then 500 mg daily) was started. On the second hospital day, serum CK and troponin T level raised to 6,476 U/L and 60 ng/L, respectively. Blood cultures (two bottles on day 2) became positive for S. marcescens, which was sensitive to quinolones. The urine culture showed no growth. He became apyretic within 48 hours and the rest of the hospital course was uneventful. When the patient was discharged asymptomatic 8 days after admission, his serum CK concentration had decreased to 228 U/L. At a follow-up visit 1 month after discharge, he remained well and laboratory studies (including CK and troponin T values, liver function tests, and convalescent serologic assessment) revealed normal results. At a second follow-up evaluation 6 months after discharge, he went on symptoms free.. 3. Discussion. Our patient developed S. marcescens bacteremia and ...
Serratia marcescens subsp. marcescens strain ATCC 13880 clone b3 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; 23S ribosomal RNA gene, partial sequence; and tRNA-Ile and tRNA-Ala genes, complete ...
In this study, we have demonstrated that Rhs1 and Rhs2 of S. marcescens Db10 are new T6SS-dependent antibacterial effectors. Rhs2 is a DNase toxin, whereas Rhs1 carries a novel toxin domain. While this study was under way, RhsP1/Tse5 of P. aeruginosa and RhsA and RhsB of Enterobacter cloacae also were reported to be antibacterial toxins dependent on the T6SS and specific VgrG proteins for their deployment (25, 26), and IdrD has been implicated in T6SS-dependent self-recognition in Proteus mirabilis (27). However, the mode of toxicity of these other Rhs proteins has not yet been defined. Importantly, our findings reveal that Rhs effectors can play a critical role during intraspecies competition and in competition between closely related species. This is the first demonstration of Rhs-mediated interstrain competition and supports the prediction that different serovars of Salmonella deploy distinct Rhs toxins (28).. The observed importance of Rhs effectors during intraspecies competition is ...
Cytotoxin purification. A 0.5-ml pre-culture of S. marcescens (6) was inoculated into 500 ml Davis minimal medium (8) in a 1-liter Erlenmeyer flask with shaking at 150 rpm and incubated at 37ºC for 18-24 h. Six liters of culture from 12 such flasks was centrifuged at 10,000 g for 15 min at 4ºC and ammonium sulfate was added slowly to the culture supernatant to 80% saturation. After centrifugation at 10,000 g for 15 min at 4ºC, the pellet collected was dissolved in 25 mM Tris-HCl, pH 7.0, followed by exhaustive dialysis against the same buffer. The preparation was applied to a DEAE Sepharose Fast Flow column (3.0 x 9.0 cm; Pharmacia LKB Biotechnology, Uppsala, Sweden) equilibrated with 25 mM Tris-HCl buffer, pH 7.0, and the cytotoxin was eluted (5-ml fractions) with the same buffer containing 0.1 M NaCl. Fractions with toxicity were pooled, concentrated to 5 ml by ultrafiltration through a PM 10 membrane (Amicon Corp., Lexington, MA, USA) and applied to a Sephadex G100 column (2.5 x 68 cm; ...
In molecular biology, enzymes in the DNA/RNA non-specific endonuclease family of bacterial and eukaryotic endonucleases EC 3.1.30.- share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. A histidine has been shown to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion. Friedhoff P, Gimadutdinow O, Pingoud A (August 1994). Identification of catalytically relevant amino acids of the extracellular Serratia marcescens endonuclease by alignment-guided mutagenesis. Nucleic Acids Res. 22 (16): 3280-7. doi:10.1093/nar/22.16.3280. PMC 523719 . PMID 8078761. This article incorporates text from the public domain Pfam and InterPro ...
1968-1972 Dissertation and Postdoctoral Papers. Nestle M, Sussman M. The effect of cyclic-AMP on morphogenesis and enzyme accumulation in Dictyostelium discoideum. Developmental Biology 1972;28:545-554.. Nestle M, Roberts WK. An extracellular nuclease from Serratia marcescens. II. Specificity of the enzyme. Journal of Biological Chemistry 1969;244:5219-5225.. Nestle M, Roberts WK. An extracellular nuclease from Serratia marcescens. I. Purification and some properties of the enzyme. Journal of Biological Chemistry 1969;244:5213-5218.. Nestle M, Roberts WK. Separation of ribonucleosides and ribonucleotides by a one-dimensional paper chromatographic system. Analytical Biochemistry 1968;22:349-351.. ...
RESULTS: Among 122 Serratia isolates, 117 (95.9%) were Serratia marcescens and 110 (90.2%) were of nosocomial origin. During the study period, the 122 isolates showed a high rate of resistance to third‐generation cephalosporins (45.9%) and extended‐spectrum penicillins (56.6%). The resistance rate to ciprofloxacin was 32.0%. The resistance rate to third‐generation cephalosporins increased from 31.7% for 1991 to 1995 to 54.9% for 1996 to 1998 and 50.0% for 1999 to 2001. In the multivariate analysis, prior use of a second‐generation cephalosporin (adjusted odds ratio [OR], 5.90; 95% confidence interval [CI95], 1.41 to 24.6; P = .015) or a third‐generation cephalosporin (OR, 3.26; CI95, 1.20 to 8.87; P = .020) was a strong independent risk factor for resistance to third‐generation cephalosporins. The overall case‐fatality rate was 25.4% (Serratia bacteremia-related case‐fatality rate, 13.1 ...
General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin. ...
General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin. ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
The ς32 homologs of the gamma subdivision analyzed here exhibit 65 to 80% identity in amino acid sequence to E. coli ς32 and ca. 45% identity between E. coli and the alpha proteobacteria (19). As expected, the sequence similarity was particularly high for the conserved regions 2.4 and 4.2, which are involved in promoter recognition, and the regions 2.1 and 2.2, which are involved in binding to core RNA polymerase (9). Such high conservation is consistent with the fact that these homologs can at least partly replace ς32, presumably by catalyzing specific transcription from heat shock promoters when expressed in E. coli (1, 16, 19-23, 34). In line with the structural and functional similarities, all RpoH homologs tested, including that of A. tumefaciens, were able to induce the DnaK and GroE heat shock proteins to appreciable although variable extents (Fig. 1). Furthermore, they were shown to initiate transcription from start sites identical to those used by E. coli ς32, although the ...
The pGEX-6P-1 constructs allowed for IPTG-inducible production of ChiX and variants as N-terminal GST fusion proteins with PreScission protease sites located between the GST and target proteins. Escherichia coli BL21 (GOLD) harbouring the plasmids was grown at 37°C in LB medium to an OD600 of 0.7. Protein production was induced by the addition of IPTG to a final concentration of 2 mM, the temperature reduced to 21°C and growth allowed to continue for a further 17 h. Cells were harvested by centrifugation at 4500×g for 40 min at 4°C and the cell pellet was suspended in 10 ml of TBS (Tris-HCl-buffered saline, pH 7.6) buffer supplemented with DNAse (Sigma-Aldrich). Cells were lysed by passage through a homogeniser (EmulsiFlex-C3) three times. The cell lysate was then clarified by centrifugation (40 000×g at 4°C) for 45 min. The supernatant was passed through a 0.45 µM filter to remove remaining particulates before incubation with 1 ml of TBS equilibrated glutathione 48 sepharose 4B beads (GE ...
Hovedmålet i dette studiet var å sammenligne bruk av isotermisk titreringskalorimetri (ITC) og overflateplasmonresonans (SPR) ved bindingsstudier mellom KitinaseB(ChiB) og kitooligosakkarider (KOS) av ulik lengde. Det ble utført forsøk med N-acetyl-D-glukosamin ((GlcNAc)3, (GlcNAc)4 og (GlcNAc)6) med ChiB-E144Q på Biacore. Det ble brukt to ulike immobiliseringsmetoder av proteinet. De samme KOS ble også studert på ITC ved 18 °C. Begge immobiliseringsmetodene ga samsvarende resultater med resultatene fra ITC. Det var derfor mulig å kombinere informasjonen fra ITC og SPR til å gi et bilde av interaksjonene mellom protein og ligand. Resultatene fra SPR tyder på at assosiasjonsraten, ka, øker med økende substratlengde. Dette er som forventet, da lengre substrater har flere gunstige interaksjoner med enzymet. Det ser ut til at dissosiasjonsraten, kd, er uavhengig av substratlengden. Dette kan skyldes at dissosiasjon av uspaltede oligomere domineres av det som skjer i -2 til +1 subsetene. ...
Passaro DJ, Waring L, Armstrong R, et al. Postoperative Serratia marcescens wound infections traced to an out-of-hospital source. J Infect Dis 1997;175:992-995. 30. Shopsin B, Kreiswirth BN. Molecular epidemiology of methicillinresistant Staphylococcus aureus. Emerg Infect Dis 2001;7:323-326. 31. Enright MC, Day NPJ, Davies CE, et al. Multilocus sequence typing for characterization of methicillin-resistant and methicillinsusceptible clones of Staphylococcus aureus. J Clin Microbiol 2000;38:1008-1015. DNA chip technology ante portas. J Mol Med 1999;77:761-768. 27. Demarta A, Tonolla M, Caminada A, et al. Epidemiological relationships between Aeromonas strains isolated from symptomatic children and household environments as determined by ribotyping. Eur J Epidemiol 2000;16:447-453. 28. Lai E, Birren B, Clark S, et al. Pulsed field gel electrophoresis. Biotechniques 1989;7:34-42. 29. Passaro DJ, Waring L, Armstrong R, et al. Postoperative Serratia marcescens wound infections traced to an ...
In 2002, she determined that the pathogen of White pox is Serratia marcescens, which is a bacterium. She knew that Serratia marcescens was a pathogen found in human waste. But at the time, I could only speculate that humans were the source of the pathogen to the marine environment and so I began a widespread study to determine where the pathogen was coming from and how it was getting to the marine environment, says Sutherland ...
Each antibiotic is presented in three columns. The first column lists the name of the antibiotic. The middle column represents susceptibility in percent to that antibiotic. The 3rd column represents the number of isolates tested for that specific antibiotic ...
TY - JOUR. T1 - Outbreaks of Serratia marcescens bacteriuria in a neurosurgical intensive care unit of a tertiary care teaching hospital. T2 - A clinical, epidemiologic, and laboratory perspective. AU - Yoon, Hee Jung. AU - Choi, Jun Yong. AU - Park, Yoon Soo. AU - Kim, Chang Oh. AU - Kim, June Myung. AU - Yong, Dong Eun. AU - Lee, Kyung Won. AU - Song, Young Goo. PY - 2005/12. Y1 - 2005/12. N2 - Background: Serratia marcescens is an aerobic gram-negative bacillus belonging to the family Enterobacteriacea. Infections caused by S marcescens may be difficult to treat because of their resistance to a variety of antibiotics, including β-lactams and aminoglycosides. Methods: This study aimed to (1) identify the risk factors associated with the development of Serratia marcescens bacteriuria in neurosurgical intensive care units (NSICU); (2) genotype the pathogens to determine the source of infection; (3) compare these results with antibiograms; and (4) determine and implement appropriate control ...
TY - JOUR. T1 - Functional gene cloning and characterization of the SsmE multidrug efflux pump from Serratia marcescens. AU - Minato, Yusuke. AU - Shahcheraghi, Fereshteh. AU - Ogawa, Wakano. AU - Kuroda, Teruo. AU - Tsuchiya, Tomofusa. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2008/3. Y1 - 2008/3. N2 - We cloned a gene responsible for multidrug resistance from chromosomal DNA of Serratia marcescens, and determined the nucleotide sequence. We designated the gene as ssmE. The deduced amino acid sequence of SsmE showed high similarity with the small multidrug resistance (SMR)-type multidrug efflux pumps. Cells of Escherichia coli KAM32, a drug hyper-susceptible mutant, transformed with a plasmid pESM437 carrying the ssmE gene showed elevated minimum inhibitory concentrations of structurally unrelated antimicrobial agents. E. coli KAM32/pESM437 showed elevated energy dependent efflux of ethidium. Reverse transcriptase polymerase chain reaction (RT-PCR) analysis ...
The third chitinase gene (chiC) of Serratia marcescens 2170, specifying chitinases C1 and C2, was identified. Chitinase C1 lacks a signal sequence and consists of a catalytic domain belonging to glycoside hydrolase family 18, a fibronectin type III-like domain (Fn3 domain) and a C-terminal chitin-binding domain (ChBD). Chitinase C2 corresponds to the catalytic domain of C1 and is probably generated by proteolytic removal of the Fn3 and ChBDs. The loss of the C-terminal portion reduced the hydrolytic activity towards powdered chitin and regenerated chitin, but not towards colloidal chitin and glycol chitin, illustrating the importance of the ChBD for the efficient hydrolysis of crystalline chitin. Phylogenetic analysis showed that bacterial family 18 chitinases can be clustered in three subfamilies which have diverged at an early stage of bacterial chitinase evolution. Ser. marcescens chitinase C1 is found in one subfamily, whereas chitinases A and B of the same bacterium belong to another ...
Eleven strains of Serratia were isolated from different soils and the guts of invertebrates and characterized by their sensitivity to eight indigenous bacteriophages. They were also classified according to bacteriocin production and sensitivity, BiOLOG plate and API 20E strip profiles and 16S rRNA sequence information. One strain was thus identified as Serratia plymuthica, another as Serratia fonticola. The remaining strains were shown to be closely related to Serratia proteamaculans subsp. quinovora Grimont et al. 1983 after DNA-DNA cross-hybridization demonstrated relatedness greater than 70% with the type strain of this subspecies. From an ecological perspective, our results illustrated the wide variation in sensitivity that closely related Serratia strains have towards various indigenous soil phages and that these phages have broad host ranges within the genus. Furthermore, the phage and bacteriocin interactions within the Serratia strains examined were intricate and did not reflect phylogenetic
Two exotic fungal isolates, one of Beauveria bassiana (268-86) and another of Metarhizium anisopliae (100-82), three local isolates of B. bassiana (isolates I, II, III) and one of the entomogenous bacteria Serratia marcescens, were tested for pathogenicity against the banana weevil Cosmopolites sordidus. All four isolates of B. bassiana and the one of M. anisopliae were found to be pathogenic to third-instar larvae of C. sordidus, causing mortalities of 98-100% by 9 days post-exposure to dry fungal spores. M. anisopliae was the least pathogenic to larvae with LT50 of 4.2 days, compared to 3.5, 3.3, 3.6 and 4.0 respectively for isolates I, II, III and 268-86. B. bassiana was also pathogenic to adult C. sordidus, causing mortalities varying from 63-97% by 35 days post-exposure depending on isolate. As for larvae M. anisopliae exhibited low pathogenicity for the adult C. sordidus. In general, all the fungi tested were less pathogenic to adult weevils (LT50 = 17.5; 12.5; 8.0 and 22.0 days) for ...
Two exotic fungal isolates, one of Beauveria bassiana (268-86) and another of Metarhizium anisopliae (100-82), three local isolates of B. bassiana (isolates I, II, III) and one of the entomogenous bacteria Serratia marcescens, were tested for pathogenicity against the banana weevil Cosmopolites sordidus. All four isolates of B. bassiana and the one of M. anisopliae were found to be pathogenic to third-instar larvae of C. sordidus, causing mortalities of 98-100% by 9 days post-exposure to dry fungal spores. M. anisopliae was the least pathogenic to larvae with LT50 of 4.2 days, compared to 3.5, 3.3, 3.6 and 4.0 respectively for isolates I, II, III and 268-86. B. bassiana was also pathogenic to adult C. sordidus, causing mortalities varying from 63-97% by 35 days post-exposure depending on isolate. As for larvae M. anisopliae exhibited low pathogenicity for the adult C. sordidus. In general, all the fungi tested were less pathogenic to adult weevils (LT50 = 17.5; 12.5; 8.0 and 22.0 days) for ...
Because of its red pigmentation, caused by expression of the pigment prodigiosin,[13] and its ability to grow on bread, S. marcescens has been evoked as a naturalistic explanation of Medieval accounts of the miraculous appearance of blood on the Eucharist that led to Pope Urban IV instituting the Feast of Corpus Christi in 1264. This followed celebration of a Mass at Bolsena in 1263, led by a Bohemiantransubstantiation, or the turning of bread and wine into the Body and Blood of Christ during the Mass. During the Mass, the Eucharist appeared to bleed and each time the priest wiped away the blood, more would appear. This event is celebrated in a fresco in the Apostolic Palace in the Vatican City, painted by Raphael.[14] priest who had doubts concerning ...
Patients were treated with contaminated intravenous feeding bags.. Nine Alabama hospital patients who were treated with contaminated intravenous feeding bags have died and the maker has pulled the product off the market, state health officials said Tuesday.. Ten more people treated with the bags that provide nutrients through IV tubes also were sickened by the outbreak of serratia marcescens bacteria, health officials said. However, officials have not definitively tied the deaths to the bacterial outbreak at six hospitals, State Health Officer Donald Williamson said.. There is nothing to suggest the deaths were directly related to the bacterial infection, says Williamson.. On March 16, two hospitals reported increased cases of serratia marcescens to the Alabama Department of Public Health. Officials linked the infection to TPN, a common nutritional supplement delivered by IV tubes.. A single pharmacy, Birmingham-based Meds IV, made the bags. Williamson said the company has notified its ...
From September 20 to 27, 1950, the U.S. Navy ran Operation Sea-Spray to study biological weapons in San Francisco. They then monitored the population and recorded a dramatic increase in pneumonia and UTIs without telling them why it was happening. In the following days, the military took samples at 43 sites to track the bacteria…
From September 20 to 27, 1950, the U.S. Navy ran Operation Sea-Spray to study biological weapons in San Francisco. They then monitored the population and recorded a dramatic increase in pneumonia and UTIs without telling them why it was happening. In the following days, the military took samples at 43 sites to track the bacteria…
In article ,01HNUX051MGI0027IO at vax.rhodes.edu, HILL at NS.RHODES.EDU writes: ,From: HILL at NS.RHODES.EDU ,Subject: Re: Need help on MR-VP test ,Date: 7 Mar 1995 12:56:41 -0800 ,Pong Nim writes: ,,I am having problem obtaining a positive test for Methy Red (MR) ,,and Voges-Proskauer (VP) reaction. ,,I have grew Enterobacter aerogenes & Serratia marcescens in ,,MR-VP broth at 35 C for 48 hrs. Five drops of MR were added. ,,on one set of MR-VP broth. Twelve drops of VP reagent I and ,,three drops of VP reagent II were added to the second set of ,,MR-VP broth. All reagents were made fresh on the day of the test. ,,Still I cant seem to get any positive reaction at all. What ,,am I doing wrong. Your helpful advice would greatly be appreciate. ,In reply: ,The Enterobacter, of course, should be negative for the MR test -- and while ,some S. marcescens will be positive, not all will be. So probably you just ,have an MR-negative strain of Serratia. Try over with E. coli, and I bet itll ,work. ,As ...
Serrapeptase is a protein decomposition enzymes produced by bacteria serratia . Can decompose slow bradykinin, fibrin and fibrinogen.
How many inches tall is a sixteen Oz monster energy can? Which of the following is inside the thylakoid membrane? Still, pancreatic A ganglion is also called a synovial hernia or synovial cyst. Without this pumping action, the stroma would swell with water, become hazy, and ultimately turn the cornea opaque, rendering the eye blind. It is trans-parent to light, providing two-thirds of the refractive power required to focus light on the retina. This serves two functions in the both the light-dependent and light-independent (Calvin cycle) reactions. A model of a chloroplast is shown below. Serratia marcescens (S. marcescens) is a gram-negative bacillus that occurs naturally in soil and water and produces a red pigment at room temperature. In â ¦ connective tissue that holds the bones and organs in place. The stroma begins to express Foxd1 once the ureteric bud invades into the metanephric mesenchyme at E11, making it the earliest identifier of the renal stroma , . The iris consists of two ...
The structures of CBM5 domains have been elucidated for an endoglucanase, CBDEGZ from Erwinia chrysanthemi (EcEGZCBM5) and two chitinases ChBDChiB from Serratia marcescens (SmChiBCBM5) and ChBDChiC from Streptomyces griseus HUT6037 (SgChiCCBM5) [1, 2, 5]. The three structures revealed that CBM5 is composed of five β-strands (β1-5). The β1, β2 and β3 forms the principle structure and the additional short β-strands (β4 and β5) form an antiparallel β-sheet which is independent of the main strand (Figure 1). The EcEGZCBM5 resembles a ski-boot or L-shaped structure composed of only β-sheets [5]. Helix structures have not been found in CBM5 modules. There are a few differences in CBM5 modules of endo-glucanases (EcEGZCBM5) and chitinases (SmChiBCBM5 and SgChiCCBM5). The EcEGZCBM5 possesses a conserved disulfide bond between Cys4 and Cys61. These disulfide bonds have not been reported in SmChiBCBM5 and SgChiCCBM5. CBM5 modules possess surface exposed aromatic residues which interact with ...
The structures of CBM5 domains have been elucidated for an endoglucanase, CBDEGZ from Erwinia chrysanthemi (EcEGZCBM5) and two chitinases ChBDChiB from Serratia marcescens (SmChiBCBM5) and ChBDChiC from Streptomyces griseus HUT6037 (SgChiCCBM5) [1, 2, 5]. The three structures revealed that CBM5 is composed of five β-strands (β1-5) [1, 2, 5]. The β1, β2 and β3 forms the principle structure and the additional short β-strands (β4 and β5) form an antiparallel β-sheet which is independent of the main strand (Figure 1). The EcEGZCBM5 resembles a ski-boot or L-shaped structure composed of only β-sheets [5]. Helix structures have not been found in CBM5 modules. There are a few differences in CBM5 modules of endo-glucanases (EcEGZCBM5) and chitinases (SmChiBCBM5 and SgChiCCBM5). The EcEGZCBM5 possesses a conserved disulfide bond between Cys4 and Cys61 [5]. These disulfide bonds have not been reported in SmChiBCBM5 and SgChiCCBM5 [1, 2]. CBM5 modules possess surface exposed aromatic residues ...
1I7S: The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan.
The Escherichia coli single-strand binding protein [1] (gene ssb), also known as the helix-destabilizing protein, is a protein of 177 amino acids. It binds tightly, as a homotetramer, to single-stranded DNA (ss-DNA) and plays an important role in DNA replication, recombination and repair. Closely related variants of SSB are encoded in the genome of a variety of large self-transmissible plasmids. SSB has also been characterized in bacteria such as Proteus mirabilis or Serratia marcescens. Eukaryotic mitochondrial proteins that bind ss-DNA and are probably involved in mitochondrial DNA replication are structurally and evolutionary related to prokaryotic SSB. Proteins currently known to belong to this subfamily are listed below [2]: ...
Clinical findings a. Symptoms and signs most infections mild priority with online viagra buy shipping but infected will have a limited number of bacteria and destroy the antigen fig. Lancet. Comparison with - lactamase production are enterobacter species, p. Aeruginosa, serratia marcescens, escherichia coli, klebsiella pneumoniae, but significant number of patients, more often in critical care of children with ghd have normal intelligence. Cerebral spinal fluid and protein s deficiency should be performed. Left heart failure with hypervolemia owing to multiple classes. The physician is always required if there is an acute-phase reactantfib-rinogen levels are elevated, with many causes of bradycardia with atropine. The hib conjugate vaccine receipt and guillain-barr syndrome. Larger and major vessels entered. Differential diagnosis obstructive sleep apnea, upper airway obstruction eg, enlarged tonsils, especially if pulsatile, variations in tissue damage. Tee is particularly relevant when the ...
Recent studies investigating the gut immune response to indigenous microbiota and following ingestion of bacterial pathogens, including both natural fly pathogens (Erwinia carotovora [75,76], Pseudomonas entomophila [77], Serratia marcescens [78]), and mammalian pathogens that disrupt homeostasis and can be lethal to flies (e.g. P. aeruginosa [79], Vibrio cholerae [80]), have shown that the two main gut epithelial responses to microbes are the production of reactive oxygen species (ROS) by the NADPH oxidase enzyme Duox, and the production of AMPs by the Imd-Relish (NF-κB) pathway [21,75,81]. Duox activity is stimulated by uracil, a microbe-derived ligand, which is released by pathogenic bacteria and certain members of the microbiota that can become pathogenic (sometimes referred to as pathobionts) [82]. To prevent excessive epithelial damage by the production of ROS, Drosophila employs an inducible catalase and negative regulators of Duox activity [83,84]. Another recently identified host ...
Hosts exhibit a variety of defence mechanisms against parasites, including avoidance. Both host-parasite coevolutionary dynamics and the host mating system can alter the evolutionary trajectories of populations. Does the nature of host-parasite interactions and the host mating system affect the mechanisms that evolve to confer host defence? In a previous experimental evolution study, mixed mating and obligately outcrossing Caenorhabditis elegans host populations adapted to either coevolving or static Serratia marcescens parasite populations. Here, we assessed parasite avoidance as a mechanism underlying host adaptation. We measured host feeding preference for the coevolved and static parasites vs preference for Escherichia coli, to assess the evolution of avoidance behaviour within our experiment. We found that mixed mating host populations evolved a preference for E. coli relative to the static parasite strain; therefore, the hosts evolved parasite avoidance as a defence. However, mixed mating ...
Goodbye American Greatness: Interestingly, one of the surest ways of learning much of which the US is guilty of doing, is by listening to what the US accuses others of doing. This is the US which used parts of its own population who, unaware of anything, were subjected to chemical and biological tests conducted by the US government as it developed its biological weapons program. Part of the tests were conducted as part of the Pentagons Project 112 test program. Starting in 1949, the US Army conducted open-air tests of simulated biological organisms over populated areas of the US, even when published medical research proved that the organisms could sicken or kill healthy persons. In 1950, during Operation Sea Spray, San Francisco was secretly sprayed by the US Navy with Serratia marcescens and Bacillus globigii bacteria in a germ warfare test, that led to an outbreak of pneumonia in a hospital, killing at least one person. Nearly every single San Francisco resident inhaled particles from the ...
While Caenorhabditis elegans specifically responds to infection by the up-regulation of certain genes, distinct pathogens trigger the expression of a common set of genes. We applied new methods to conduct a comprehensive and comparative study of the transcriptional response of C. elegans to bacterial and fungal infection. Using tiling arrays and/or RNA-sequencing, we have characterized the genome-wide transcriptional changes that underlie the hosts response to infection by three bacterial (Serratia marcescens, Enterococcus faecalis and otorhabdus luminescens) and two fungal pathogens (Drechmeria coniospora and Harposporium sp.). We developed a flexible tool, the WormBase Converter (available at http://wormbasemanager.sourceforge.net/), to allow cross-study comparisons. The new data sets provided more extensive lists of differentially regulated genes than previous studies. Annotation analysis confirmed that genes commonly up-regulated by bacterial infections are related to stress responses. We found
p,,strong,Background:,/strong, Otamiri river server as a source of water for domestic activities, urban farming, recreation, aquatic foods in Owerri and environs. It also receives untreated domestic, industrial and agricultural waste water and run offs from the municipality. Seepages from solid wastes dumps at the river banks and sand mining activity going on in the river could also constitute environmental hazards,/p, ,p,,strong,Aims:,/strong, This study aims at evaluating the interactive effects of the ternary mixtures of sodium dodecyl sulfate (SDS) and some divalent metals on preponderant bacterium (,em,Serratia marcescens,/em, (SerEW01)) from the river.,/p, ,p,,strong,Study Design:,/strong, Fixed ratio ray design was used for the study, with inhibition of dehydrogenase activity as end point.,/p, ,p,,strong,Place and Duration of Study:,/strong,    Owerri, Imo State, Nigeria, June - December, 2019.,/p, ,p,,strong,Methodology:,/strong, The bacterium was earlier isolated as the ...
Are you just looking at gram stains, motility and morphology? You will probably be able to identify some by the colour and appearance of the colonies (clusters/single cells/chains etc.) You might be lucky and get a few with distinctive colours, like Serratia Marcescens, which is bright red. Do you have access to antibiotics/antibiotic plates to test for resistance, if you do youll have to do a bit of research to see which species are naturally resistant. You could do spore stains using Malachite green, if its available. That might be useful for any Gram positive species(e.g. Bacillus ...
Depression buy cheap sildalis periodically hurts and leaves a person feeling hopeless and withdrawn from society? Use caution when administering gabapentin with CNS depressants! • Goodkin K, Vrancken MAE, Feaster D: On the putative efficacy of the antidepressants in chronic, benign pain syndromes: an update! The second form of protection is deferral of removal See 8 CFR. [11 ]​ El tadalafilo inhibe PDE11 más que el sildenafilo o el vardenafilo. Similar obnoxiously nizral shampoo buy online mutants have been found in Serratia marcescens, Enterobacterspp, and Campylobacter ( 39). I was on 10 mg, pixies of the forest and ramped up to 20 mg fairly quickly, which was like a shock to my body! El sildenafil sirve para tratar la disfunción eréctil porque aumenta el flujo sanguíneo hacia el pene durante la estimulación sexual! If granted, pixies of the forest SIJ status will allow the child to remain in the United States and to become a lawful permanent resident, with no waiting period. ...
This post discusses Serratia bacteria, a common genus which commonly appears in wet areas, including bathrooms where it often leaves a pink stain.
Serrapeptase works as a natural anti-inflammatory when released into the bloodstream. As a proteolytic enzyme its isolated from Serratia E15. Clinical studies have shown that serrapeptase has an anti-inflammatory effect along with being anti-edemic, meaning that it prevents fluid retention and swelling in tissues.
Serratia marcescens. Listeria species. E. coli. Klebsiella species. Pseudomonas cepacia, a.k.a. Burkholderia cepacia. Nocardia ...
cremoris and Serratia marcescens. Clausenol is active against a number of Gram-positive and Gram-negative bacteria and fungi, ...
Serratia marcescens) ,- Inflorescence Pink rot (Serratia marcescens) "Large" Red Palm Weevil, "Picudo rojo" (Rhynchophorus ...
Angerer A, Klupp B, Braun V (1992). "Iron transport systems of Serratia marcescens". J. Bacteriol. 174 (4): 1378-87. PMC 206435 ...
... is the red dyestuff produced by many strains of the bacterium Serratia marcescens, as well as other Gram-negative, ... The ability of pigmented strains of Serratia marcescens to grow on bread has led to a possible explanation of Medieval ... Role of prodigiosin in phosphate-starved Serratia marcescens. Abstract of the Annual Meeting, American Society for Microbiology ... Yu, Victor L. (1979). "Serratia marcescens - Historical Perspective and Clinical Review". New England Journal of Medicine. 300 ...
Serratia marcescens metalloproteinase, Pseudomonas aeruginosa alk. protease, Serratia marcescens metalloprotease) is an enzyme ... Doerr M, Traub WH (May 1984). "Purification and characterization of two Serratia marcescens proteases". Zentralblatt für ... Serralysin (EC 3.4.24.40, Pseudomonas aeruginosa alkaline proteinase, Escherichia freundii proteinase, Serratia marcescens ... Serratia marcescens and Erwinia chrysanthemi. Morihara K, Tsuzuki H, Oka T (March 1968). "Comparison of the specificities of ...
Glasziou KT (1956). "The metabolism of arginine in Serratia marcescens. II Carbamyladenosine diphosphate phosphoferase". Aust. ...
Serratia marcescens. 14756 0.65 µm. Lactobacillus brevis. To determine the pore diameter, physical methods such as porosimetry ...
SM - Serratia marcescens. *P - Serratia marcescens. *AF - Aspergillus fumigatus mutant C-2 ...
Goldenberg DT, Harinandan A, Walsh MK, Hassan T (Spring 2010). "Serratia Marcescens Endophthalmitis After 20-Gauge Pars Plana ...
... produced by non-pathogenic enterobacterium Serratia sp. E-15, now known as Serratia marcescens ATCC 21074. This microorganism ... Serratiopeptidase (Serratia E-15 protease, also known as serralysin, serrapeptase, serratiapeptase, serratia peptidase, ... The enzyme was also described by Miyata K, Maejima K, Tomoda K, Isono M (1970). "Serratia protease. Part I. Purification and ... Serratiopeptase is produced by purification from culture of Serratia E-15 bacteria. It is a member of the Peptitase M10B ( ...
... aeruginosa Serratia marcescens Enterococcus faecalis Peptococcus spp. Peptostreptococcus spp. Mezlocillin can be made in a ...
Serratia marcescens, especially for the history of prodigiosin's discovery Sakai-Kawada, Francis E.; Ip, Courtney G.; Hagiwara ... The prodiginines are a family of red tripyrrole dyestuffs produced by Gammaproteobacteria (e.g. Serratia marcescens) as well as ... especially Serratia marcescens. They are also found in Actinomycetes, for example Streptomyces coelicolor and some marine ... Undecylprodigiosin Butyl-meta-cycloheptylprodiginine The prodiginines are secondary metabolites originally noted in Serratia ...
Serratia marcescens, Citrobacter freundii, and Morganella morganii in Korea. European Journal of Clinical Microbiology and ... Citrobacter freundii and Serratia marcescens: a multicentre study from Korea. Journal of Antimicrobial Chemotherapy. 60, 868- ... and Serratia marcescens: a multicenter study from Korea. Diagnostic Microbiology and Infectious Diseases. 63, 314-318 (2009). ...
White pox disease, caused by the bacterium Serratia marcescens. Yellow-band disease, possibly caused by a unidentified species ... and White pox disease by the bacterium Serratia marcescens. H. corallasia is a sessile protozoan that secretes a bottle-like ...
... and homoisoleucine in Serratia marcescens". Journal of Biochemistry. 80 (2): 333-9. doi:10.1093/oxfordjournals.jbchem.a131281. ...
1958). "Dissimilation of C14-labeled Glucose by Serratia marcescens." Journal of Bacteriology. 75(4): 492-493. Wasserman, A. E ...
White pox disease, caused by the bacterium Serratia marcescens. Yellow-band disease AKA Yellow blotch disease, thought to be ...
Alberti, L; Harshey, RM (1990). "Differentiation of Serratia marcescens 274 into swimmer and swarmer cells". Journal of ... Swarming motility was first reported by Jorgen Henrichsen and has been mostly studied in genus Serratia, Salmonella, Aeromonas ... Eberl, L; Molin, S; Givskov, M (1999). "Surface Motility of Serratia liquefaciens MG1". Journal of Bacteriology. 181 (6): 1703- ...
Kida Y, Inoue H, Shimizu T, Kuwano K (January 2007). "Serratia marcescens serralysin induces inflammatory responses through ...
"Extended Epidemic of Nosocomial Urinary Tract Infections Caused by Serratia marcescens". Journal of Clinical Microbiology. 41 ( ...
Like other third-generation cephalosporins, ceftriaxone is active against Citrobacter spp., Serratia marcescens, and beta- ... Some organisms, such as Citrobacter, Providencia, and Serratia, have the ability to become resistant through the development of ...
Within the ATCC the micro-organism is alternatively named Serratia marcescens Bizio. The preparation and some uses of the ... Serratia E-15 protease, otherwise known as serratiopeptidase, first prepared in the late 1960s, is obtained from Serratia sp. E ... Examples include Serratia E-15 protease (Serratiopeptidase) (see also separate references in this list); Wobenzym (a mixture of ... The material is also described in Miyata K, Maejima K, Tomoda K, Isono M (February 1970). "Serratia protease: Part I. ...
... s are expressed in several bacteria including Pseudomonas aeruginosa and Serratia marcescens. In humans, the ...
Drouillard S, Armand S, Davies GJ, Vorgias CE, Henrissat B (1997). "hem J. 1997 Dec 15;328 ( Pt 3):945-9. Serratia marcescens ...
"Spontaneous Bacterial Peritonitis Causing Serratia Marcescens and Proteus Mirabilis Ventriculoperitoneal Shunt Infection. Case ...
Serratia marcescens, Pseudomonas putida and Nocardia farcinica. The enzyme has a molecular weight of 74,000 and a turnover ... "Analysis of oxidation sensitivity of maleate cis-trans isomerase from Serratia marcescens". Bioscience, Biotechnology, and ...
The NucE protein (TC# 1.E.25.2.1) in Serratia marcescens shows homology to phage holin proteins involved in releasing lysozyme ... Berkmen, M.; Benedik, M. J.; Bläsi, U. (1997-10-01). "The Serratia marcescens NucE protein functions as a holin in Escherichia ... Jin, S.; Chen, Y.; Christie, G. E.; Benedik, M. J. (1996-02-23). "Regulation of the Serratia marcescens extracellular nuclease ... "The NucE and NucD lysis proteins are not essential for secretion of the Serratia marcescens extracellular nuclease". ...
"Crystal Structure and Binding Properties of the Serratia marcescens Chitin-binding Protein CBP21". Journal of Biological ...
1982) "Superattenuation in the tryptophan operon of Serratia marcescens" Nature 298:38-41. I Stroynowski, M Soloski, MG Low, ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
"Any patient of any age with a CGD type infection (Staphylococcus aureus, Burkholderia cepacia complex, Serratia marcescens, ... "Any patient of any age with a CGD type infection (Staphylococcus aureus, Burkholderia cepacia complex, Serratia marcescens, ... "Any patient of any age with a CGD type infection (Staphylococcus aureus, Burkholderia cepacia complex, Serratia marcescens, ... "Any patient of any age with a CGD type infection (Staphylococcus aureus, Burkholderia cepacia complex, Serratia marcescens, ...
Serratia marcescens. *Shewanella. *Staphylococcus. *Staphylococcus epidermidis. *Streptococcus. *Streptococcus lactarius. * ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
Serratia marcescens (Serratia infection) · Citrobacter koseri/Citrobacter freundii. Lac-. H2S+. Salmonella enterica (ടൈഫോയ്ഡ്, ...
Serratia marcescens. *Shewanella. *Shigella. *Staphylococcus. *Staphylococcus epidermidis. *Streptococcus lactarius. * ...
The main function of hormone-sensitive lipase is to mobilize the stored fats. Mobilization and Cellular Uptake of Stored Fats (with Animation) HSL functions to hydrolyze either a fatty acid from a triacylglycerol molecule, freeing a fatty acid and diglyceride, or a fatty acid from a diacylglycerol molecule, freeing a fatty acid and monoglyceride. Another enzyme found in adipose tissue, Adipose Triglyceride Lipase (ATGL), has a higher affinity for triglycerides than HSL, and ATGL predominantly acts as the enzyme for triglyceride hydrolysis in the adipocyte. HSL is also known as triglyceride lipase, while the enzyme that cleaves the second fatty acid in the triglyceride is known as diglyceride lipase, and the third enzyme that cleaves the final fatty acid is called monoglyceride lipase. Only the initial enzyme is affected by hormones, hence its hormone-sensitive lipase name. The diglyceride and monoglyceride enzymes are tens to hundreds of times faster, hence HSL is the rate-limiting step in ...
Hariliku sibula mahlast valmistatud vesiekstrakt inhibeeris in vitro katsetes bakterite Escherichia coli, Serratia marcescens, ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
Serratia marcescens. 14756 0.65 µm. Lactobacillus brevis. To determine the pore diameter, physical methods such as porosimetry ...
... streptococcus pyogenes and serratia marcescens. The formula change to the use of dead bacteria drastically reduced the risk of ...
... researchers used the microscopic roundworm Caenorhabditis elegans as a host and the pathogenic bacteria Serratia marcescens to ... Then they exposed those populations to the S. marcescens parasite. It was found that the self-fertilizing populations of C. ...
Although a clear consensus has not been reached, a large number of scientists adhere to a substrate-transport model to account for the catalytic properties of glucose 6-phosphatase. In this model, glucose 6-phosphatase has a low degree of selectivity. The transfer of the glucose 6-phosphate is carried out by a transporter protein (T1) and the endoplasmic reticulum (ER) contains structures allowing the exit of the phosphate group (T2) and glucose (T3).[6] Glucose 6-phosphatase consists of 357 amino acids, and is anchored to the endoplasmic reticulum (ER) by nine transmembrane helices. Its N-terminal and active site are found on the lumen side of the ER and its C-terminus projects into the cytoplasm. Due to its tight association to the ER, the exact structure of glucose 6-phosphatase remains unknown. However, sequence alignment has shown that glucose 6-phosphatase is structurally similar to the active site of the vanadium-containing chloroperoxidase found in Curvularia inaequalis.[7] Based on pH ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac-. H2S+. *Salmonella enterica *Typhoid ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
Serratia marcescens nuclease. *Micrococcal nuclease. Retrieved from "https://en.wikipedia.org/w/index.php?title=PETase&oldid= ...
... researchers used the microscopic roundworm Caenorhabditis elegans as a host and the pathogenic bacterium Serratia marcescens to ... Then they exposed those populations to the S. marcescens parasite. It was found that the self-fertilizing populations of C. ...
Serratia marcescens 5'CCCGGG 3'GGGCCC 5'---CCC GGG---3' 3'---GGG CCC---5' ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
... and Serratia marcescens. Somewhat poorer activity is observed for the Klebsiella and Enterobacter species, with the MIC90 for ...
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is O-phosphoserine phosphohydrolase. This enzyme participates in glycine, serine and threonine metabolism. ...
... and homoisoleucine in Serratia marcescens". Journal of Biochemistry. 80 (2): 333-9. PMID 794063.. ...
White pox disease, which only affects elkhorn coral, is caused by a fecal enterobacterium, Serratia marcescens. The disease is ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
Serratia marcescens (Serratia infection) · Citrobacter koseri/Citrobacter freundii. Lac-. H2S+. Salmonella enterica (Typhoid ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
Serratia marcescens *Serratia infection. *Citrobacter koseri/Citrobacter freundii. Lac−. H2S+. *Salmonella enterica *Typhoid ...
"Serratia marcescens". NCBI Taxonomy Browser. 615. Type strain of Serratia marcescens at BacDive - the Bacterial Diversity ... Serratia marcescens. (2011, April). Retrieved from https://microbewiki.kenyon.edu/index.php/Serratia_marcescens Hejazi A; ... microbiologyinfo.com/biochemical-test-and-identification-of-serratia-marcescens/ "Serratia". Soil Microbiology, Environmental ... Serratia marcescens (/səˈreɪʃiə mɑːrˈsɛsɪnz/)[failed verification] is a species of rod-shaped, Gram-negative bacteria in the ...
Serratia+marcescens+nuclease at the US National Library of Medicine Medical Subject Headings (MeSH) Serratia marcescens ... Serratia marcescens nuclease (EC 3.1.30.2, endonuclease (Serratia marcescens), barley nuclease, plant nuclease I, nucleate ...
Serratia marcescens Bizio. 43425™. Product category. Bacteria. Strain designation. McClung 304 [5305] Type strain. No Product ... Serratia marcescens Bizio Depositors. LS McClung Chain of custody. ATCC <-- LS McClung <-- M. Fulton 5303 <-- Sneath <-- C.E. ... To download a certificate of origin for Serratia marcescens Bizio (43425), enter the lot number exactly as it appears on your ... To download a certificate of analysis for Serratia marcescens Bizio (43425), enter the lot number exactly as it appears on your ...
Each antibiotic is presented in three columns. The first column lists the name of the antibiotic. The middle column represents susceptibility in percent to that antibiotic. The 3rd column represents the number of isolates tested for that specific antibiotic ...
Serratia marcescens ATCC ® 14756™ Designation: PCI 1107 TypeStrain=False Application: Membrane filter testing Sterility ... Serratia marcescens Bizio (ATCC® 14756™) Strain Designations: PCI 1107 / Type Strain: no / Biosafety Level: 1 ...
... André B. S. Saidenberg, Rodrigo H. F. Teixeira, Claudete S. ... "Serratia marcescens Infection in a Swallow-tailed Hummingbird," Journal of Wildlife Diseases, 43(1), 107-110, (1 January 2007) ... "Serratia marcescens Infection in a Swallow-tailed Hummingbird," Journal of Wildlife Diseases 43(1), 107-110, (1 January 2007). ... and cardiac blood were collected for microbiologic exams yielding pure cultures of a pigmented strain of Serratia marcescens. ...
Serratia marcescens WCF Domain: Prokaryote Optimal Growth Medium: Brain Heart Infusion Agar Optimal Growth Temperature: 25° C ... Genus and Species: Serratia marcescens WCF. Domain: Prokaryote. Optimal Growth Medium: Brain Heart Infusion Agar. Optimal ... Serratia marcescens WCF, Living, Tube. Item # 155456 *bvseo_sdk, java_sdk, bvseo-4.0.0 ...
Serratia marcescens Domain: Prokaryote Optimal Growth Medium: Nutrient Agar Optimal Growth Temperature: 25° C Package: ... Genus and Species: Serratia marcescens. Domain: Prokaryote. Optimal Growth Medium: Nutrient Agar. Optimal Growth Temperature: ... Serratia marcescens, MicroKwik Culture®, Vial. Item # 155450A *bvseo_sdk, java_sdk, bvseo-4.0.0 ...
The species, Serratia marcescens is the main pathogen under the genus Serratia. Strains of S. marcescens produce prodigiosin, ... "Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factors" ... "Antagonism of Serratia marcescens towards Phytophthora parasitica and its effects in promoting the growth of citrus" ... Serratia marcescens. From Citizendium, the Citizens Compendium. Revision as of 02:46, 14 May 2009 by Shamina Haque (Talk , ...
tr,Q54276,Q54276_SERMA Chitinase OS=Serratia marcescens OX=615 GN=chiB PE=1 SV=1 ...
sp,P08664,MERB_SERMA Alkylmercury lyase OS=Serratia marcescens OX=615 GN=merB PE=3 SV=1 ... Serratia marcescens. ,p>This subsection of the ,a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and ...
... G.V. Carbonell1, C.R.N. Amorim1, M.T. Furumura1, A.L.C. Darini2, B.A.L. ... Serratia marcescens cytotoxin was purified to homogeneity by ion-exchange chromatography on a DEAE Sepharose Fast Flow column, ... Figure 2. Analysis of Serratia marcescens cytotoxin by SDS-PAGE using silver staining. Lane A, Cytotoxic fraction obtained from ... Serratia marcescens has been considered to be an important nosocomial pathogen, responsible for endemic and epidemic infections ...
Serratia marcescens Chitinase B complexed with azide inhibitor. *DOI: 10.2210/pdb3WD3/pdb ... We have previously reported a specific Serratia marcescens chitinase B (SmChiB)-templated syn-triazole inhibitor generated in ... We have previously reported a specific Serratia marcescens chitinase B (SmChiB)-templated syn-triazole inhibitor generated in ... Serratia marcescens. Mutation(s): 0 Gene Names: chiB. EC: 3.2.1.14. Find proteins for P11797 (Serratia marcescens) ...
In this study, we investigated the Yersinia enterocolitica (YfuA) and Serratia marcescens (SfuA) iron-binding periplasmic ... In this study, we investigated the Yersinia enterocolitica (YfuA) and Serratia marcescens (SfuA) iron-binding periplasmic ... Crystal Structure of iron-free Serratia marcescens SfuA. *DOI: 10.2210/pdb1XVY/pdb ...
Buy Techne DNA Serratia marcescens, with mastermix and more from our comprehensive selection of Techne Human Microbial Pathogen ...
There have been no other cases of Serratia marcescens infections. Given that there are no other cases on Serratia marcescens ... alt="Update on Increased Incidence of Serratia Marcescens" /> Update on Increased Incidence of Serratia Marcescens ... "Serratia marcescens can be naturally occurring in the gut and its presence on or in the body (colonisation) is not harmful in ... Serratia marcescens colonisation in settings such as this is a recognised UK wide occurrence which is why we screen for it ...
Mouse monoclonal Serratia marcescens antibody [B/N4N]. Validated in ELISA, ICC/IF. Immunogen corresponding to tissue, cells or ... Serratia marcescens is a species of Gram negative bacteria in the family Enterobacteriaceae. It is a broad host range pathogen ... Primary - Mouse Anti-Serratia marcescens antibody [B/N4N] (ab69236) ELISA, ICC/IF ... marcescens is involved in hospital-acquired infections, particularly in urinary tract and wound infections. Serratia species ...
V. L. Yu, "Serratia marcescens: historical perspective and clinical review," The New England Journal of Medicine, vol. 300, no ... V. L. Yu, "Serratia marcescens-historical perspective and clinical review," The New England Journal of Medicine, vol. 300, no. ... A. Hejazi and F. R. Falkiner, "Serratia marcescens," Journal of Medical Microbiology, vol. 46, no. 11, pp. 903-912, 1997. View ... Serratia marcescens is an opportunistic pathogenic Gram-negative bacillus that has emerged as a serious cause of nosocomial ...
Mechanisms of Bacterial (Serratia marcescens) Attachment to, Migration along, and Killing of Fungal Hyphae.. Hover T1, Maya T1 ... We have found a remarkable capacity for the ubiquitous Gram-negative rod bacterium Serratia marcescens to migrate along and ... Mechanisms of Bacterial (Serratia marcescens) Attachment to, Migration along, and Killing of Fungal Hyphae ... Mechanisms of Bacterial (Serratia marcescens) Attachment to, Migration along, and Killing of Fungal Hyphae ...
Skin ulcers caused by Serratia marcescens: three cases and a review of the literature. Eur J Dermatol. 2016;26:373-6. DOI ... Serratia marcescens: an Italian story. Int J Dermatol. 2017;56:795-6. DOIPubMed ... Serratia marcescens was later renamed Monas prodigiosus in 1846, then Bacillus prodigiosus, before the original name was ... Nazzaro G. Etymologia: Serratia marcescens. Emerging Infectious Diseases. 2019;25(11):2012. doi:10.3201/eid2511.et2511.. ...
Species of Serratia occur as commensal fauna in the intestinal mucous membranes of man & mammals. S. marcescens is occasionally ... gram-negative bacteria Serratia marcescens, showing the characteristic convex curve of the end walls displayed by the 2 ... Species of Serratia occur as commensal fauna in the intestinal mucous membranes of man & mammals. S. marcescens is occasionally ... Caption: False-colour transmission electron micrograph (TEM) of the rod-shaped, gram-negative bacteria Serratia marcescens, ...
Petri dish containing a nutrient medium that has been used to culture the bacterium Serratia marcescens. This is a facultative ... Serratia marcescens culture. Petri dish containing a nutrient medium that has been used to culture the bacterium Serratia ... serratia marcescens, specimen Licence fees: A licence fee will be charged for any media (low or high resolution) used in your ... marcescens. This is a facultative anaerobic gram-negative rod bacterium. The red pigment it produces has been used in research ...
The chitinolytic machinery of Serratia marcescens is one of the best known enzyme systems for the conversion of insoluble ... The chitinolytic machinery of Serratia marcescens--a model system for enzymatic degradation of recalcitrant polysaccharides.. ...
Serratia marcescens strain JPP1 was isolated from peanut hulls in Huaian city, Jiangsu Province, China. Its potential to ... Potential of Chitinolytic Serratia marcescens Strain JPP1 for Biological Control of Aspergillus parasiticus and Aflatoxin. Kai ... These characteristics suggest that S. marcescens JPP1 strain could potentially be utilized for the biological control of ...
Differentiation of Serratia marcescens 274 into swimmer and swarmer cells. Message Subject (Your Name) has forwarded a page to ... Differentiation of Serratia marcescens 274 into swimmer and swarmer cells.. L Alberti, R M Harshey ... We describe a new sensory response in the enteric bacterium Serratia marcescens. When grown in liquid media, the bacteria were ... To identify conditions that influence this differentiation, the growth environment of S. marcescens was manipulated extensively ...
... produced by Serratia marcescens TN9106, which was expressed by Echerichia coli JM109 cells. Mercaptoacetic acid and 2- ... Inhibition of the metallo-beta-lactamase produced from Serratia marcescens by thiol compounds Biol Pharm Bull. 1997 Nov;20(11): ... produced by Serratia marcescens TN9106, which was expressed by Echerichia coli JM109 cells. Mercaptoacetic acid and 2- ...
Cornea-damaging proteases of Serratia marcescens. You will receive an email whenever this article is corrected, updated, or ... A S Kreger, O K Griffin; Cornea-damaging proteases of Serratia marcescens.. Invest. Ophthalmol. Vis. Sci. 1975;14(3):190-198. ... Fractionation of the culture supernatant fluids of Serratia marcescens, strain BG, by ammonium sulfate precipitation, ... Immunization against experimental Pseudomonas aeruginosa and Serratia marcescens keratitis. Vaccination with lipopolysaccharide ...
... marcescens sternal abscess that occurred 13 years after CABG. Chronic sternal infections due to this organism in cardiac ... Chronic Serratia marcescens sternal infection presenting 13 years after coronary artery surgery. *. ... ConclusionThis report described the presentation and treatment of a chronic S. marcescens sternal abscess that occurred 13 ...
Hospital isolates of Serratia marcescens able to transfer resistance to up to 11 antibiotics were found to contain conjugative ... An R plasmid of Serratia marcescens transferable to Pseudomonas aeruginosa Chemotherapy. 1982;28(1):6-17. doi: 10.1159/ ... Hospital isolates of Serratia marcescens able to transfer resistance to up to 11 antibiotics were found to contain conjugative ...
Infection of Serratia marcescens by bacteriophage chi. Message Subject (Your Name) has forwarded a page to you from Journal of ...
  • Strains of S. marcescens produce prodigiosin, the pigment that gives the bacteria its unique red color. (citizendium.org)
  • Some strains of S. marcescens are capable of producing a pigment called prodigiosin, which ranges in color from dark red to pale pink. (abcam.com)
  • Most S. marcescens strains are resistant to several antibiotics because of the presence of R factors in plasmids. (abcam.com)
  • Flagellum-defective strains of S. marcescens were able to migrate along zygomycete hyphae, although they were significantly slower than the wild-type strain and were delayed in fungal killing. (nih.gov)
  • Some strains of S. marcescens are capable of producing pigment, the intensity of which ranges from dark red to pale pink, depending on the age of the colonies. (antimicrobe.org)
  • Using the S. marcescens DB10/DB11 strain as a model [ 1 ], genetic experiments isolated many mutant strains that are compromised in chitinase secretion [ 11 ]. (biochemj.org)
  • Mutation of the genes encoding the cytolysin ShlA and its transporter ShlB resulted in attenuated S. marcescens strains that failed to cause profound weight loss, extended illness, hemorrhage, and prolonged lung pathology in mice. (asm.org)
  • An 8-year surveillance study in Taiwan identified multiple S. marcescens strains that were resistant to the antibiotics ciprofloxacin and levofloxacin ( 9 ). (asm.org)
  • In conjugational crosses, three Klebsiella pneumoniae strains and one Serratia marcescens strain have been demonstrated to transfer resistance determinants to newer types of cephalosporins. (springer.com)
  • While Klebsiella strains donated cefotaxime, cefamandole and cefuroxime resistance to Escherichia coli K-12 recipients, the genetic analysis of exconjugants after the transfer of plasmids from Serratia strains to Proteus or Salmonella recipients showed that the cefoxitin resistance determinant was also co-transferred. (springer.com)
  • Since the discovery of SME-1, three sets of imipenem-resistant S. marcescens strains have been isolated from different regions of the United States. (asm.org)
  • Serological typing has also been used and this method seems to be a suitable first-line typing method for S. marcescens , although some strains remain untypable. (microbiologyresearch.org)
  • All MR strains of S. marcescens and some mannose-sensitive strains were agglutinated by the MAbs. (mysciencework.com)
  • The serological homogeneity of MR fimbriae was confirmed by a spot test, using the crude purified fimbriae from several MR strains of S. marcescens. (mysciencework.com)
  • It should be mentioned that not all pathogenic strains of Serratia produce this red coloration . (microblife.in)
  • The aim of the present study was to develop a method for identification of strains of Serratia marcescens that is also suitable for use in the epidemiologic studies. (docphin.com)
  • 40 clinical strains of Serratia marcescens were investigated by using the polymerase chain reaction (PCR). (docphin.com)
  • A scaffold of the genome was produced with Contiguator2, and we identified the closest related strain by BLASTing the scaffold, returning strains S. marcescens SM39 and FS14 as closely related but not identical, as was evidenced by a large inversion and numerous small insertions and deletions in the genome. (asm.org)
  • abstract = "The cardiovascular and metabolic effects of an endotoxin derived from Serratia marcescens were examined in anaesthetized, spontaneously‐breathing cats. (elsevier.com)
  • abstract = "BACKGROUND AND OBJECTIVE: To describe the clinical features and treatment outcomes of 10 patients with culture-proven Serratia marcescens endophthalmitis. (elsevier.com)
  • abstract = "Primary acute cutaneous infections caused by Serratia marcescens are extremely unusual. (uab.cat)
  • Serratia marcescens (/səˈreɪʃiə mɑːrˈsɛsɪnz/)[failed verification] is a species of rod-shaped, Gram-negative bacteria in the family Yersiniaceae. (wikipedia.org)
  • Serratia marcescens are gram-negative bacteria which fall under the tribe Klebsielleae and the large family Enterobacteriaceae. (citizendium.org)
  • However given the vulnerability of premature babies, Serratia marcescens infections, where the colonised bacteria gets into the bloodstream, can occur. (nhsggc.org.uk)
  • Serratia marcescens is a species of Gram negative bacteria in the family Enterobacteriaceae. (abcam.com)
  • S. marcescens migration did not require fungal viability or surrounding growth medium, as bacteria migrated along aerial hyphae as well.S. marcescens did not exhibit growth tropism toward zygomycete mycelium. (nih.gov)
  • Sehdev PS , Donnenberg MS . Arcanum: the 19th-century Italian pharmacist pictured here was the first to characterize what are now known to be bacteria of the genus Serratia. (cdc.gov)
  • False-colour transmission electron micrograph (TEM) of the rod-shaped, gram-negative bacteria Serratia marcescens, showing the characteristic convex curve of the end walls displayed by the 2 bacteria at centre. (sciencephoto.com)
  • An illegal diversion of opioids by a hospital nurse tampering with syringes was responsible for a cluster outbreak of Serratia marcescens , a gram-negative bacteria, according to research published online today in Infection Control & Hospital Epidemiology , the journal of the Society for Healthcare Epidemiology of America. (medicalxpress.com)
  • However, microscopial examination failed to reveal red blood cells but did show a large number of gram-negative bacteria, which proved to be S. marcescens. (antimicrobe.org)
  • The aims of the investigation are to identify the effect of bacteria, for example, what effect can Serratia marcescens pilli on red blood cells gives when mixed with molecular inhibitor. (ukessays.com)
  • Serratia Marcescens is a particularly deadly bacteria, especially among drug abusers and addicts. (deadlymicrobes.com)
  • Hi Mom123, The best way to kill the Serratia bacteria is to wash and then thoroughly dry the clothing and washcloths. (deadlymicrobes.com)
  • From soil to crop to plate, or from healthcare worker to wound to the connective tissues of the central nervous system , highly motile Serratia bacteria are equipped to take every opportunity and colonize within a living organism . (microblife.in)
  • Rod-shaped bacteria, bacilliform bacteria or bacilli describe the typical shape of Serratia marcescens . (microblife.in)
  • Serratia bacteria emit extracellular enzymes such as AmpC type β-lactamases , elastase, gelatinase, lecithinase, alkaline protease, and caseinase, all of which increase bacterial resistance to antimicrobial therapies. (microblife.in)
  • We hypothesize that S. marcescens has a set of genes whose products alter the direct interaction of the peptides with the bacteria. (emerging-researchers.org)
  • The ability of A. tristis to transmit S. marcescens after molting to the adult stage suggests that the hemocoel acts as the site of retention of transmissible bacteria. (usda.gov)
  • Prodigiosin is a heterocyclic bacterial secondary metabolite belonging to the class of tripyrrole compounds, synthesized by various types of bacteria including Serratia species. (frontiersin.org)
  • We have found a remarkable capacity for the ubiquitous Gram-negative rod bacterium Serratia marcescens to migrate along and kill the mycelia of zygomycete molds. (nih.gov)
  • Culture plate containing the bacterium Serratia marcescens . (cdc.gov)
  • Petri dish containing a nutrient medium that has been used to culture the bacterium Serratia marcescens. (sciencephoto.com)
  • We describe a new sensory response in the enteric bacterium Serratia marcescens. (asm.org)
  • The Gram-negative bacterium Serratia marcescens secretes many proteins that are involved in extracellular chitin degradation. (portlandpress.com)
  • In research laboratories employing Drosophila fruit flies, infection of them with S. marcescens is common. (wikipedia.org)
  • A rare clinical form of gastroenteritis occurring in early infancy caused by infection with S. marcescens. (wikipedia.org)
  • André B. S. Saidenberg , Rodrigo H. F. Teixeira , Claudete S. Astolfi-Ferreira , Terezinha Knöbl , and Antonio J. Piantino Ferreira " Serratia marcescens Infection in a Swallow-tailed Hummingbird," Journal of Wildlife Diseases 43(1), 107-110, (1 January 2007). (bioone.org)
  • NHS Greater Glasgow and Clyde's Public Health Protection Unit and Infection Control Team continue to investigate following an increased incidence of serratia marcescens in the unit. (nhsggc.org.uk)
  • Given that there are no other cases on Serratia marcescens infection and that all the appropriate infection control procedures are in place the unit will continue to admit new patients. (nhsggc.org.uk)
  • Infection of Serratia marcescens by bacteriophage chi. (asm.org)
  • Four of the five patients recovered, while one died from Serratia sepsis infection. (medicalxpress.com)
  • Leah M. Schuppener et al, Serratia marcescens Bacteremia: Nosocomial Cluster Following Narcotic Diversion, Infection Control & Hospital Epidemiology (2017). (medicalxpress.com)
  • In our study we used Gram negative pathogenic organism Serratia marcescens which can cause disease to human also Serratia marcescens genome has pili on cell surface for adherence to the epithelial cells and cause infection. (ukessays.com)
  • This study describes a model of S. marcescens pneumonia that mimics known clinical features of human illness, identifies neutrophils and the toxin ShlA as a key factors important for defense and infection, respectively, and provides a solid foundation for future studies of novel therapeutics for this important opportunistic pathogen. (asm.org)
  • Over the last 30 years, Serratia marcescens has become an important cause of nosocomial infection. (microbiologyresearch.org)
  • Pigment (prodigiosin) biosynthesis by S. marcescens has been investigated fully since the emergence of the organism as a cause of infection. (microbiologyresearch.org)
  • Antibiotics used to treat serratia infection include β-lactam agents, aminoglycosides and fluoroquinolones and a variety of different resistance mechanisms have been demonstrated. (microbiologyresearch.org)
  • Serratia marcescens is the most common species of Serratia found in hospitals, and the only pathogenic species of Serratia, except for rare reports of diseases resulting from infection with Serratia plymuthica,Serratia liquefaciens, Serratia rubidaea, and Serratia odorifera. (benjaminpohle.com)
  • Serratia Marcescens is also commonly found in respiratory tract infection. (deadlymicrobes.com)
  • From contaminated water supplies to the passing on of a single bacterium in critical care wards, this bacterium's ability to multiply in far from ideal conditions and its resistance to treatment means a Serratia infection is potentially fatal. (microblife.in)
  • Of the eight species implicated in clinical infection S. marcescens, S. liquefaciens and S. odorifera are best known. (blogspot.com.au)
  • Early in this century, this distinctive red pigmentation of S. marcescens, combined with an apparent low level of virulence, led to its use as a biological marker of infection. (blogspot.com.au)
  • Consequently, S. marcescens was used in a number of classic bacterial transmission experiments, which led to improved understanding of the epidemiology of infection. (blogspot.com.au)
  • In this study we report a nosocomial outbreak of surgical site infection and catheter insertion site infection due to S. marcescens. (bvsalud.org)
  • The species, Serratia marcescens is the main pathogen under the genus Serratia. (citizendium.org)
  • Serratia marcescens has been considered to be an important nosocomial pathogen, responsible for endemic and epidemic infections, especially in newborns and patients submitted to invasive procedures (1-4). (scielo.br)
  • Of this bacterial group, Serratia marcescens is the main human pathogen. (hindawi.com)
  • Serratia marcescens is a Gram-negative opportunistic bacterial pathogen of the Enterobacteriaceae and is estimated to be responsible for ∼1.4% of nosocomial infections [ 1 , 2 ]. (portlandpress.com)
  • S. marcescens is also an antibiotic-resistant opportunistic pathogen and is among the top 10 causative agents of bloodstream bacterial infections in North America, with a mortality rate of 41% ( 1 - 3 ). (asm.org)
  • Serratia Marcescens is a human pathogen, which means that it is known to cause disease in humans. (schmidtlaw.com)
  • Obtained from the CDC Public Health Image Library Description and Significance Serratia marcescens is a motile,short rod-shaped, Gram-negative, facultative anaerobe bacterium, classified as an opportunistic pathogen. (benjaminpohle.com)
  • Serratia marcescens is an opportunistic, gram negative, nosocomial pathogen which belongs to family, Enterobacteriaceae. (benjaminpohle.com)
  • Serratia marcescens is an opportunistic gram-negative pathogen and one of the main Enterobacteriaceae responsible for hospital-acquired infections. (microblife.in)
  • Of all Serratia species, S. marcescens is the most common clinical isolate and the most important human pathogen. (blogspot.com.au)
  • Retention or loss of transmissibility after molting was tested for adult and nymphal squash bug, Anasa tristis (De Geer), a natural vector of the plant pathogen Serratia marcescens Bizio, the causal agent of cucurbit yellow vine disease. (usda.gov)
  • Serratia marcescens is a Gram-negative, rare, but clinically important nosocomial pathogen that causes meningitis and blood sepsis ( 1 - 3 ). (asm.org)
  • To download a certificate of analysis for Serratia marcescens Bizio ( 43425 ), enter the lot number exactly as it appears on your product label or packing slip. (atcc.org)
  • The certificate of analysis for that lot of Serratia marcescens Bizio ( 43425 ) is not currently available online. (atcc.org)
  • Bartolomeo Bizio, a Venetian pharmacist, studied the mode of transmission of the red substance and named this microorganism Serratia in honor of Serafino Serrati, who ran the first steamboat on the Arno River in 1795, anticipating the discovery of Robert Fulton in 1807. (cdc.gov)
  • Serratia marcescens was later renamed Monas prodigiosus in 1846, then Bacillus prodigiosus , before the original name was restored in the 1920s in recognition of the work of Bizio. (cdc.gov)
  • Serratia was named in honor of an Italian physicist, Serafino Serrati, who Bizio thought had been slighted in favor of American inventors as to priority for the invention of the steamboat. (antimicrobe.org)
  • Marcescens is derived from the Latin word 'to decay' since Bizio observed that the pigment deteriorated quickly, dissolving from a light-pink material into a purplish-red, viscous form. (antimicrobe.org)
  • Bizio named the genus Serratia in honor of and Italian physicist named Serratia, and chose marcescens for the species name after the Latin word for decay [3]. (benjaminpohle.com)
  • Some biological properties of the cytotoxin were analyzed and compared with well-characterized toxins, such as VT1, VT2 and CNF from Escherichia coli and hemolysin produced by S. marcescens . (scielo.br)
  • A new type of hemophore-dependent heme acquisition system of Serratia marcescens reconstituted in Escherichia coli. (asm.org)
  • Während Klebsiella -Stämme Resistenz gegen Cefotaxim, Cefamandol und Cefuroxim auf Escherichia coli K-12-Empfängerstämme übertrugen, zeigte die genetische Analyse der Exkonjuganten nach Übertragung von Plasmiden von Serratia -Stämmen auf Proteus - oder Salmonella -Empfängerstämme, daß die Determinante für Cefoxitin-resistenz ebenfalls mit übertragen wurde. (springer.com)
  • The cloned ompA gene from Serratia marcescens was fully expressed in Escherichia coli and its product correctly assembled into the outer membrane. (epfl.ch)
  • About 40% of the amino acid sequence was identical among AmpC beta-lactamases resided in S. marcescens, Citrobacter freundii OS60, Escherichia coli K12 and Enterobacter cloacae P99. (semanticscholar.org)
  • Irradiation of aerosols of either Escherichia coli or Serratia marcescens with simulated solar xenon radiation caused a significant decrease in viability. (dtic.mil)
  • We cloned a gene smfY for multidrug efflux pump from chromosomal DNA of Serratia marcescens using drug-hypersensitive Escherichia coli KAM32 as the host, and characterized the pump. (elsevier.com)
  • We fully reconstituted the has signalling cascade of Serratia marcescens in Escherichia coli. (pasteur.fr)
  • Due to this, and because S. marcescens produces a reddish-orange tripyrrole dye called prodigiosin, it may cause staining of the teeth. (wikipedia.org)
  • The biochemical pathway for the production of prodigiosin by S. marcescens has been characterized by analyzing what intermediates become accumulated in specific mutants. (wikipedia.org)
  • S. marcescens is now accepted as a member of the Enterobacteriaceae order and a bacterium that, along with others within the Serratia genus , often produces a red pigment known as prodigiosin. (microblife.in)
  • Because of its red pigmentation, caused by expression of the pigment prodigiosin , [13] and its ability to grow on bread, S. marcescens has been evoked as a naturalistic explanation of Medieval accounts of the "miraculous" appearance of blood on the Eucharist that led to Pope Urban IV instituting the Feast of Corpus Christi in 1264. (blogspot.com)
  • Our study showed that prodigiosin (500 μM) (extracted from Serratia marcescens culture) and a prodigiosin/copper(II) (100 μM each) complex have strong RNA and dsDNA cleaving properties while they have no pronounced effect on protein. (frontiersin.org)
  • Water-washed Serratia marcescens (ATCC strain 14041) cells were lyophilized in an all-glass system capable of evacuation to pressures of less than 5 × 10 -6 torr. (asm.org)
  • Shrimp shell powders (SSP) were fermented by successive two-step fermentation of Serratia marcescens B742 and Lactobacillus plantarum ATCC 8014 to extract chitin. (oregonstate.edu)
  • The identified optimal fermentation conditions for extracting chitin from SSP using S. marcescens B742 were 2% SSP, 2 h of sonication time, 10% incubation level and 4 d of culture time, while that of using L. plantarum ATCC 8014 fermentation was 2% SSP, 15% glucose, 10% incubation level and 2 d of culture time. (oregonstate.edu)
  • Mr. Trivedi's biofield energytreatment on S. marcescens for changes in sensitivity pattern of antimicrobial, biochemical characteristics, and biotype number.S. marcescens cells were procured from MicroBioLogics Inc., USA in sealed pack bearing the American Type CultureCollection (ATCC 13880) number and divided into two groups, Group (Gr.) I: control and Gr. II: treated. (peerevaluation.org)
  • Different enzymes have been identified in S. marcescens that contribute to its pathogenic nature, such as chitinase, lipase, chloroperoxidase and an extracellular protein, HasA [2] . (citizendium.org)
  • Killing does not depend on the secretion of S. marcescens chitinases, as mutants in which all three chitinase genes were deleted retained wild-type killing abilities. (nih.gov)
  • The third chitinase gene ( chiC ) of Serratia marcescens 2170, specifying chitinases C1 and C2, was identified. (portlandpress.com)
  • The production of different enzymes by S. marcescens as virulence factors has also been reported, including chitinase, lipase, chloroperoxidase and an extracellular protein, HasA. (microbiologyresearch.org)
  • S. marcescens is a motile organism and can grow in temperatures ranging from 5-40 °C and in pH levels ranging from 5 to 9. (wikipedia.org)
  • He named this organism Serratia marcescens. (antimicrobe.org)
  • Most carbapenem-hydrolyzing activity has been due to molecular class B metalloenzymes, such as CcrA in Bacteriodes fragilis ( 23 ) and IMP-1 in organisms such as Pseudomonas aeruginosa and Serratia marcescens ( 9 , 20 ). (asm.org)
  • lycopersici with Bacillus cereus energized the low activity and it was more significant with Serratia marcescens and Trichoderma harzianum for the 2nd day but with Pseudomonas fluorescens , it was for the 5th day. (scialert.net)
  • The cloning , expression and characterisation of bacterial chitin-binding proteins from pseudomonas aeruginosa , serratia marcescens, photorhabdus luminescens and photorhabdus asymbiotica. (dcu.ie)
  • Prokaryotic chitin-binding proteins from Serratia marcescens, Pseudomonas aeruginosa, Photorhabdus asymbiotica and Photorhabdus luminescens were cloned, over-expressed in E. coli and purified to homogeneity via (His)6 affinity tags. (dcu.ie)
  • The Effect of Serratia marcescens and Genetically Improved Pseudomonas fluorescens on Meloidogyne incognita', Egyptian Academic Journal of Biological Sciences, B. Zoology , 8(1), pp. 49-59. (ekb.eg)
  • Serratia species cause 1.4% of nosocomial bloodstream infections with an associated mortality of 25% [in USA]. (abcam.com)
  • Serratia species are Gram-negative facultative anaerobic bacilli of the Enterobacteriaceae group that are known to cause a spectrum of clinical diseases in humans including osteomyelitis and septic arthritis [ 2 , 3 ]. (hindawi.com)
  • S. marcescens 1 (red) was cocultured at a 45° angle to various mold species (white). (nih.gov)
  • The word marcescens was chosen from Latin for the species name meaning to decay, reflecting the rapid deterioration of the pigment. (cdc.gov)
  • Species of Serratia occur as commensal fauna in the intestinal mucous membranes of man & mammals. (sciencephoto.com)
  • PCR-based plasmid analyses identified blaNDM-1 in association with conjugative IncFII plasmids in both S. marcescens and K. pneumoniae, suggesting inter-species transfer of blaNDM-1, possibly from K. pneumoniae into a well-established hospital-adapted S. marcescens clone. (deepdyve.com)
  • Species Serratia marcescens on an XLD agar plate. (benjaminpohle.com)
  • Serratia marcescens is found in fresh and stagnant water or saline, in the soil, and in plants, insects, and animals including the human species . (microblife.in)
  • Sequences of homologous beta-lactamases from clinical isolates of Serratia marcescens with different substrate specificities. (semanticscholar.org)
  • These beta-lactamases were produced by clinical isolates of Serratia marcescens, isolates GN16694 and GN19450, respectively. (semanticscholar.org)
  • S. marcescens is occasionally pathogenic in humans, presenting in long term, chronically sick patients in whom they may cause septicaemia. (sciencephoto.com)
  • In preliminary experiments, we observed that a potent entomopathogen, Serratia marcescens, can colonize the midgut of Riptortus insects and was recovered from the midgut when Serratia cells were orally administered, suggesting that this pathogenic bacterium can escape host immune defenses in the salivary fluid. (ovid.com)
  • Previously thought to be non-pathogenic, S. marcescens became a recognized name when consciously used in U.S. military experiments in the 1940s and 1960s. (microblife.in)
  • S. marcescens is commonly involved in hospital-acquired infections (HAIs), particularly catheter-associated bacteremia, urinary tract infections, and wound infections, and is responsible for 1.4% of HAI cases in the United States. (wikipedia.org)
  • There have been no other cases of Serratia marcescens infections. (nhsggc.org.uk)
  • S. marcescens is involved in hospital-acquired infections, particularly in urinary tract and wound infections. (abcam.com)
  • Serratia marcescens, which can cause nosocomial outbreaks,and urinary tract and wound infections, is abundant in damp environments ( Figure ). (cdc.gov)
  • Hospital epidemiologists conducted a review of blood cultures and molecular fingerprinting to identify the origin of the S. marcescens outbreak, concluding the possible connection between the cluster of infections and the narcotic diversion. (medicalxpress.com)
  • In newborns and immunocompromised and intensive care patients, S. marcescens can cause severe infections such as pneumonia ( 4 ), bloodstream infections ( 5 ), and urinary tract infections, surgical site infections, and ocular infections ( 6 ). (asm.org)
  • S. marcescens infections are most often associated with the hospital environment ( 5 ), but community-acquired infections are now increasingly diagnosed ( 7 ). (asm.org)
  • The most common hospital acquired infections from S. Marcescens are urinary and respiratory tract infections but it can cause a variety of other infections. (gettyimages.es)
  • have become increasingly adapted to hospital environments and have emerged as important agents of hospital-acquired infections affecting all age groups.8-10 The inherent resistance of Serratia spp. (deepdyve.com)
  • Serratia marcescens has been recognized as an important cause of nosocomial and community-acquired infections. (scirp.org)
  • Serratia marcescens has been recognized as an important cause of nosocomial and, at a lesser extent, communityacquired infections [1]. (scirp.org)
  • Serratia marcescens is normally associated with nosocomial infections like catheter-associated bacteremia. (deadlymicrobes.com)
  • Serratia Marcescens symptoms are commonly associated with urinary tract infections, but in 30% to 50% of reported cases, there are no symptoms to assist diagnosis. (deadlymicrobes.com)
  • Serratia marcescens is a widely distributed gram-negative rod, often associated to nosocomial infections . (bvsalud.org)
  • Nevertheless, Serratia infections are especially frequent in chronic granulomatous disease, which is a primary immunodeficiency that affects phagocytic cells of the innate immune system. (uab.cat)
  • We report a young man without history of infections, who developed multiple dermal abscesses on a leg with chronic lymphoedema attributed to S marcescens. (uab.cat)
  • Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens. (asm.org)
  • The DNA sequence of the chromosomal aac(6')-Ic gene from Serratia marcescens, which had been previously cloned (H. M. Champion, P. M. Bennett, D. A. Lewis, and D. S. Reeves, J. Antimicrob. (asm.org)
  • Induced expression of Serratia marcescens ribonuclease III gene in transgenic Nicotiana tabacum L. cv. (deepdyve.com)
  • Serratia marcescens is a facultative anaerobic, rod-shaped, Gram-negative bacterium that is ubiquitous in water, in soil, and on plant surfaces. (asm.org)
  • Serratia marcescens is a gram-negative rod-shaped facultatively anaerobic bacterium that is extremely motile. (microblife.in)
  • Three sets of carbapenem-resistant Serratia marcescens isolates have been identified in the United States: 1 isolate in Minnesota in 1985 (before approval of carbapenems for clinical use), 5 isolates in Los Angeles (University of California at Los Angeles [UCLA]) in 1992, and 19 isolates in Boston from 1994 to 1999. (asm.org)
  • it is also known that drug resistance in S. marcescens is significantly more prevalent than in other Enterobacteriaceae. (microblife.in)
  • Serratia marcescens is a member of the genus Serratia, which is a part of the family Enterobacteriaceae. (blogspot.com.au)
  • The enzyme with the higher pI in each strain hydrolyzed carbapenems and was not inhibited by EDTA, similar to the chromosomal class A SME-1 β-lactamase isolated from the 1982 London strain S. marcescens S6. (asm.org)
  • Three chromosomal class A β-lactamases that cause imipenem resistance have also been described: from Enterobacter cloacae , NMC-A in France ( 14 ) and IMI-1 in California ( 18 ), and from S. marcescens , SME-1 in England ( 12 ). (asm.org)
  • Nucleotide sequence of the Serratia marcescens SR50 chromosomal ampC beta-lactamase gene. (semanticscholar.org)
  • The Serratia marcescens SR50 chromosomal beta-lactamase gene (ampC) was cloned and sequenced. (semanticscholar.org)
  • Hospital isolates of Serratia marcescens able to transfer resistance to up to 11 antibiotics were found to contain conjugative R plasmids. (nih.gov)
  • Hybridization experiments utilizing a restriction fragment from the aac(6')-Ic gene showed that all S. marcescens organisms carried this gene whether or not the AAC(6')-I resistance profile was expressed. (asm.org)
  • S. marcescens has acquired notoriety in the last 20 years because of its resistance to multiple antibiotics ( 7 , 8 ). (asm.org)
  • Multiple studies have revealed an alarming increase in S. marcescens resistance to carbapenem and other β-lactam antibiotics ( 8 , 10 , 11 ). (asm.org)
  • Mutation in Serratia marcescens AmpC beta-lactamase producing high-level resistance to ceftazidime and cefpirome. (semanticscholar.org)
  • The aim of this study was to investigate the mechanisms involved in the meropenem resistance of Serratia marcescens clinical isolates. (elsevier.com)
  • The S. marcescens toxin is extracellular and heat labile, and optimal culture conditions were incubation at temperatures ranging from 30 to 37ºC for 24 h under shaking in medium adjusted to pH 8.5 (6). (scielo.br)
  • Two proteases having similar molecular weights (44,000), estimated by gel filtration, and isoelectric points of approximately 5.0 and 5.3 were obtained free of detectable amounts of other known extracellular serratia enzymes. (arvojournals.org)
  • The results support the conclusion that extracellular proteases produced in vitro by S. marcescens can elicit rapid and extensive damage to the rabbit cornea. (arvojournals.org)
  • The utilization by Serratia marcescens of heme bound to hemoglobin requires HasA, an extracellular heme-binding protein. (asm.org)
  • Many other aspects of the pathogenicity and virulence of S. marcescens have been studied, including adherence and hydrophobicity, lipopolysaccharide (LPS) and extracellular products. (microbiologyresearch.org)
  • We identified a 92-kDa iron-regulated S. marcescens outer membrane protein, HasR, which alone enabled the E. coli hemA mutant to grow on heme or hemoglobin as a porphyrin source. (asm.org)
  • Studies of the virulence factors of S. marcescens demonstrated that clinical isolates produce a toxin with activity on Vero (African Green monkey kidney) cells in culture (5). (scielo.br)
  • Serratia marcescens causes bacterial keratitis and contact lens associated complications yet its virulence factors are poorly understood. (arvojournals.org)
  • This is the first report of a multidrug efflux pump belonging to the MF superfamily in S. marcescens. (elsevier.com)
  • This discovery occurred almost immediately after detection of the S. marcescens outbreak , prompting a controlled substance diversion investigation (CSDI) by key hospital staff. (medicalxpress.com)
  • Testing of the tampered syringes suggested the nurse had replaced the active medication within the syringes with a saline or other solution, likely causing the S. marcescens outbreak. (medicalxpress.com)
  • We aimed to investigate the molecular epidemiology of S. marcescens in two Romanian hospitals over 2010-15, including a neonatal NDM-1 S. marcescens outbreak. (deepdyve.com)
  • Mar 06, · One year ago, I had one of the worst experiences a hospital epidemiologist can have: a Serratia marcescens outbreak in a neonatal department with a total of 21 colonized or infected newborns. (benjaminpohle.com)
  • An outbreak of S. marcescens and E. cloacae bacteremia in a surgical intensive care unit was traced to extrinsic contamination of the parenteral narcotic fentanyl by a health care worker. (jasonandjarvis.com)
  • Dried Serratia marcescens (ATTC strain 14041) cells were exposed to various partial pressures of oxygen and nitrogen. (asm.org)
  • Low molecular weight thiol compounds have been found to be strong inhibitors of metallo-beta-lactamase (IMP-1) produced by Serratia marcescens TN9106, which was expressed by Echerichia coli JM109 cells. (nih.gov)
  • A beta-lactamase from Serratia marcescens hydrolyzing the 2-carboxypenam T-5575. (semanticscholar.org)
  • To our knowledge, we describe the first case of S. marcescens rhabdomyolysis, most probably related to acute cholecystitis and secondary bacteremia. (scirp.org)
  • Our patient developed S. marcescens bacteremia and rhabdomyolysis, most probably related to acute cholecystitis. (scirp.org)
  • From June 30, 1998, through March 21, 1999, several patients in the surgical intensive care unit of a hospital acquired Serratia marcescens bacteremia. (jasonandjarvis.com)
  • A case was defined as the occurrence of S. marcescens bacteremia in any patient in the surgical intensive care unit during the period of the epidemic. (jasonandjarvis.com)
  • To identify risk factors, we compared patients with S. marcescens bacteremia with randomly selected controls. (jasonandjarvis.com)
  • eight (31 percent) had polymicrobial bacteremia, and seven of these had Enterobacter cloacae and S. marcescens in the same culture. (jasonandjarvis.com)
  • S. marcescens causes cucurbit yellow vine disease, leading to sometimes serious losses in melon fields. (wikipedia.org)
  • Serratia marcescens (S. marcescens) has become an important nosocomial pathogens and increased resistantisolates were reported. (peerevaluation.org)
  • alfalfae and a test isolate of Serratia marcescens showed that they differ by production of pigments with different solubility properties and absorption spectra. (apsnet.org)
  • The bacterial isolate was identified as Serratia marcescens by the 16S rRNA gene sequences. (springer.com)
  • Herein, we report the draft genome sequence for isolate ED-NGS-1015 of Serratia marcescens , cultivated from a blood sample obtained from a neonatal sepsis patient at the Royal Infirmary in Edinburgh, Scotland, United Kingdom. (asm.org)
  • Serratia marcescens nuclease (EC 3.1.30.2, endonuclease (Serratia marcescens), barley nuclease, plant nuclease I, nucleate endonuclease) is an enzyme. (wikipedia.org)
  • The chitinolytic machinery of Serratia marcescens is one of the best known enzyme systems for the conversion of insoluble polysaccharides. (nih.gov)
  • The Sanger Institute was funded by the Wellcome Trust, and CNRS, to sequence the genome of Serratia marcescens strain Db11. (citizendium.org)
  • This did not occur when the Db11 strain, a standard reference for S. marcescens, was used as the reference for mapping. (cdc.gov)
  • Typing methods used to study the epidemiology of S. marcescens include biotyping, bacteriocin typing, phage typing, plasmid analysis, polymerase chain reaction amplification of enterobacterial repetitive intergenic consensus sequences (ERIC-PCR) and ribotyping. (microbiologyresearch.org)
  • Conclusions The molecular epidemiology is most consistent with the importation of a pKOX_NDM1-like plasmid into Romania and its dissemination amongst K. pneumoniae/E. cloacae and subsequently S. marcescens across hospitals. (deepdyve.com)
  • In elkhorn coral, S. marcescens is the cause of the disease known as white pox disease. (wikipedia.org)
  • Serratia marcescens cytotoxin was purified to homogeneity by ion-exchange chromatography on a DEAE Sepharose Fast Flow column, followed by gel filtration chromatography on a Sephadex G100 column. (scielo.br)
  • In this study, a 15 kDa trialysin-like protein from the salivary gland of R. pedestris and a potent virulence factor of Serratia cells, a serralysin metalloprotease, from the culture medium of S. marcescens were successfully purified to homogeneity. (ovid.com)
  • Herein, we present the draft genome of a Serratia marcescens strain isolated from a preterm neonate in Edinburgh in 2013. (asm.org)
  • Is there a widespread clone of Serratia marcescens producing outbreaks worldwide? (cdc.gov)
  • Serratia marcescens frequently causes outbreaks in healthcare settings. (cdc.gov)
  • There are few studies using high-throughput sequencing (HTS) that analyse S. marcescens outbreaks. (cdc.gov)
  • Mechanisms of Bacterial (Serratia marcescens) Attachment to, Migration along, and Killing of Fungal Hyphae. (nih.gov)
  • Despite multiple clinical descriptions of S. marcescens nosocomial pneumonia, little is known regarding the mechanisms of bacterial pathogenesis and the host immune response. (asm.org)