Selenium: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Placebo Effect: An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.Selenomethionine: Diagnostic aid in pancreas function determination.Placebos: Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.Glutathione Peroxidase: An enzyme catalyzing the oxidation of 2 moles of glutathione in the presence of hydrogen peroxide to yield oxidized glutathione and water. EC 1.11.1.9.Selenoproteins: Selenoproteins are proteins that specifically incorporate SELENOCYSTEINE into their amino acid chain. Most selenoproteins are enzymes with the selenocysteine residues being responsible for their catalytic functions.Selenoprotein P: An extracellular selenoprotein that contains most of the SELENIUM in PLASMA. Selenoprotein P functions as an antioxidant and appears to transport selenium from the LIVER to peripheral tissues.Organoselenium Compounds: Organic compounds which contain selenium as an integral part of the molecule.Selenic Acid: A strong dibasic acid with the molecular formula H2SeO4. Included under this heading is the acid form, and inorganic salts of dihydrogen selenium tetraoxide.Selenium Radioisotopes: Unstable isotopes of selenium that decay or disintegrate emitting radiation. Se atoms with atomic weights 70-73, 75, 79, 81, and 83-85 are radioactive selenium isotopes.Selenious Acid: A selenium compound with the molecular formula H2SO3. It used as a source of SELENIUM, especially for patients that develop selenium deficiency following prolonged PARENTERAL NUTRITION.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Dietary Supplements: Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.Selenocysteine: A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Selenium Oxides: Inorganic compounds formed through the oxidation of selenium.Vitamin E: A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.Trace Elements: A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Nails: The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.Cross-Over Studies: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Antioxidants: Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.Randomized Controlled Trials as Topic: Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.Diet: Regular course of eating and drinking adopted by a person or animal.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Selenium-Binding Proteins: A group of proteins that covalently attach to selenium or SELENIUM-containing compounds.Intention to Treat Analysis: Strategy for the analysis of RANDOMIZED CONTROLLED TRIALS AS TOPIC that compares patients in the groups to which they were originally randomly assigned.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Thioredoxin-Disulfide Reductase: A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5Pain Measurement: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.Phytotherapy: Use of plants or herbs to treat diseases or to alleviate pain.Treatment Failure: A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.Single-Blind Method: A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Anti-Inflammatory Agents, Non-Steroidal: Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.Yeast, Dried: The dry cells of any suitable strain of SACCHAROMYCES CEREVISIAE or CANDIDA. It can be obtained as a by-product from the brewing of beer or by growing on media not suitable for beer production. Dried yeast serves as a source of protein and VITAMIN B COMPLEX.Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.Recurrence: The return of a sign, symptom, or disease after a remission.beta Carotene: A carotenoid that is a precursor of VITAMIN A. It is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC). (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Engewood, CO, 1995.)Vitamins: Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.Zinc: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Vitamin A: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.Pilot Projects: Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.Nutritional Status: State of the body in relation to the consumption and utilization of nutrients.Anti-Inflammatory Agents: Substances that reduce or suppress INFLAMMATION.Administration, Topical: The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.Administration, Inhalation: The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.Premedication: Preliminary administration of a drug preceding a diagnostic, therapeutic, or surgical procedure. The commonest types of premedication are antibiotics (ANTIBIOTIC PROPHYLAXIS) and anti-anxiety agents. It does not include PREANESTHETIC MEDICATION.Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Infusions, Intravenous: The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Spectrophotometry, Atomic: Spectrophotometric techniques by which the absorption or emmision spectra of radiation from atoms are produced and analyzed.Drug Combinations: Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.Selenoprotein W: A single SELENOCYSTEINE containing protein that binds reduced GLUTATHIONE and can act as an antioxidant.Anticarcinogenic Agents: Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.Bronchodilator Agents: Agents that cause an increase in the expansion of a bronchus or bronchial tubes.Administration, Cutaneous: The application of suitable drug dosage forms to the skin for either local or systemic effects.Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Delayed-Action Preparations: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.Food, Fortified: Any food that has been supplemented with essential nutrients either in quantities that are greater than those present normally, or which are not present in the food normally. Fortified food includes also food to which various nutrients have been added to compensate for those removed by refinement or processing. (From Segen, Dictionary of Modern Medicine, 1992)Deficiency Diseases: A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Probiotics: Live microbial DIETARY SUPPLEMENTS which beneficially affect the host animal by improving its intestinal microbial balance. Antibiotics and other related compounds are not included in this definition. In humans, lactobacilli are commonly used as probiotics, either as single species or in mixed culture with other bacteria. Other genera that have been used are bifidobacteria and streptococci. (J. Nutr. 1995;125:1401-12)Ointments: Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.Micronutrients: Essential dietary elements or organic compounds that are required in only small quantities for normal physiologic processes to occur.Isotopes: Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)alpha-Tocopherol: A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.White Muscle Disease: A myodegeneration most frequent in calves and lambs whose dams have been fed during gestation or longer on feeds, especially legumes (FABACEAE), grown in certain areas where selenium is either deficient or unavailable in the soil. It has been recorded in many countries. It has been produced experimentally in several species of animals on low-selenium intake. A similar myopathy occurs naturally in goats, deer, foals, and dogs but proof of the etiology is lacking. (Merck Veterinary Manual, 5th ed)Homeopathy: A system of therapeutics founded by Samuel Hahnemann (1755-1843), based on the Law of Similars where "like cures like". Diseases are treated by highly diluted substances that cause, in healthy persons, symptoms like those of the disease to be treated.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Arnica: A plant genus of the family ASTERACEAE. The dried flower heads of Arnica montana are used externally as a counterirritant and tincture for sprains and bruises, either as crude extract or in homeopathic dilution (HOMEOPATHY). Arnica contains volatile oils (OILS, VOLATILE), arnicin, arnisterol, FLAVONOIDS; TANNINS; and resin. The common name of Wolf's Bane is similar to the common name for ACONITUM.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Acute Disease: Disease having a short and relatively severe course.Injections, Subcutaneous: Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.Pain, Postoperative: Pain during the period after surgery.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Age-Related Eye Disease Study Research Group (2001). "A randomized, placebo-controlled, clinical trial of high-dose ... Klein, EA (2004). "Selenium and vitamin E cancer prevention trial". Annals of the New York Academy of Sciences. 1031: 234-41. ... Age-Related Eye Disease Study Research Group (2001). "A randomized, placebo-controlled, clinical trial of high-dose ... The range of intakes from both diet and supplements in this group was 21.6 to 1,000 IU (32 to 1,500 mg), with the median intake ...
... or placebo and followed each patient for a period of two years. In the group that received three 100 mg capsules of coenzyme ... Soon after, the product was further developed into the product sold today as Bio-Selenium+Zinc, which is still a cornerstone of ... fewer heart-related deaths compared with the placebo group. Also, there was a significant reduction in the need for ... The commercial success of Bio-Selenium+Zinc paved the road for the first daughter companies that were established in Sweden, ...
... selenium and placebo, vitamin E and placebo, or two placebos. It was one of the largest cancer prevention trials ever conducted ... A 2011 study based on the trial found that the risk of prostate cancer was elevated by 17% in the group that took vitamin E ... The review concluded that "no convincing evidence suggests that selenium supplements can prevent cancer in humans." Selenium ... "Baseline Selenium Status and Effects of Selenium and Vitamin E Supplementation on Prostate Cancer Risk". JNCI Journal of the ...
Berkely Publishing Group. New York, USA. 2001:223. *↑ Segala, M. (editor). Disease Prevention and Treatment 3rd Edition. Life ... Effects of dietary selenium on mood in healthy men living in a metabolic research unit. Biol Psychiatry. 39(2):121-128, 1996. ... Double-blind, placebo-controlled study of S-adenosyl-L-methionine in depressed post-menopausal women. Psychother Psychosom. 59( ... Avery Publishing Group, New York, USA. 1994:71. *↑ Erdmann, Robert & Jones, Meirion. The Amino Revolution. Century Hutchinson. ...
Volz HP, Kieser M (1997). "Kava-kava extract WS 1490 versus placebo in anxiety disorders--a randomized placebo-controlled 25- ... The "safe" hydrangeas belong to the Hydrangea serrata Amacha ("sweet tea") Cultivar Group. Jiaogulan, (also known as xiancao or ... Ayurvedic tea has also been found to contain nutrients including calcium, potassium, vanadium, iron, manganese, selenium and ...
The study was stopped for ethical reasons to give the placebo group the same treatment. Alpharadin uses bone targeted Radium- ... There is some tentative evidence for foods containing lycopene and selenium. Diets rich in cruciferous vegetables, soy, beans ... The predictions are based on the experience of large groups of patients suffering from cancers at various stages. In 1941, ... 2 (8): 1-4. BMJ Group (8 December 2009). "Prostate cancer: How far has your cancer spread? The TNM system". London: Guardian.co ...
January 2009). "Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E ... In the control group, 151 of the 195 patients reported some urinary incontinence (EER=.755, CER=.774, RRR=.0245, ARR=.019, NNT= ... placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma". J Natl Cancer ... Neither selenium nor vitamin E have been found to be effective in preventing prostate cancer. The trade-off dilemma refers to ...
NY: Avery Group, 3, ISBN 0-89529-769-8. *^ Drouin G, Godin JR, Pagé B (2011). "The genetics of vitamin C loss in vertebrates". ... Selenium and a Reduced Risk of Site-specific Cancers, FDA-2008-Q-0323 U.S. Food and Drug Administration. ... placebo-controlled trials". Am. Heart J. 162 (6): 959-965. doi:10.1016/j.ahj.2011.09.012. PMID 22137067.. ... a b Nutrition for Athletes, International Olympic Committee Nutrition Working Group of the Medical and Scientific Commission of ...
... versus a placebo. Compared with the placebo, men taking a daily multivitamin had a small but statistically significant ... However, specific groups of people may benefit from multivitamin supplements, for example, people with poor nutrition or those ... selenium, borate, zinc, calcium, magnesium, manganese, molybdenum, betacarotene, and/or iron. Multivitamins are typically ... A 2012 meta-analysis of ten randomized, placebo-controlled trials published in the Journal of Alzheimer's Disease found that a ...
Vadgama JV, Wu Y, Shen D, Hsia S, Block J (2000). "Effect of selenium in combination with Adriamycin or Taxol on several ... Complementary and alternative cancer treatments are often grouped together, in part because of the adoption of the phrase " ... Medicine portal Diet and cancer Clinical trial Placebo effect Pseudoscience List of topics characterized as pseudoscience " ... Milk thistle Proton therapy Selenium (Selenomethionine and Se-methylselenocysteine) Most studies of complementary and ...
Many multivitamin formulas contain vitamin C, B1, B2, B3, B5, B6, B7, B9, B12, A, E, D2 (or D3), K, potassium, iodine, selenium ... versus a placebo. Compared with the placebo, men taking a daily multivitamin had a small but statistically significant ... Zhao LQ, Li LM, Zhu H, The Epidemiological Evidence-Based Eye Disease Study Research Group EY (February 2014). "The effect of ... Safe upper levels for vitamins and minerals - Report of the UK Food Standards Agency Expert Group on Vitamins and Minerals ...
This includes vitamin A,[154][155] C,[156][157] the alpha-tocopherol form of vitamin E,[158] selenium,[159] zinc,[160][161] and ... in the 75-84 group and to 42% in the greater than 84 group.[220] Prevalence rates in less developed regions are lower.[221] The ... placebo-controlled phase I trial". Lancet. 372 (9634): 216-23. doi:10.1016/S0140-6736(08)61075-2. PMID 18640458.. ... EURODEM Incidence Research Group". Neurology. 53 (9): 1992-97. doi:10.1212/wnl.53.9.1992. PMID 10599770.. ...
van Deventer SJ, Wedel MK, Baker BF, Xia S, Chuang E, Miner PB (2006). "A Phase II dose ranging, double-blind, placebo- ... The functional enrichment analysis of this group of genes using gene ontology showed that there are many genes related with ... and selenium are extremely common and benefit from replacement therapy. Dietary interventions, including certain exclusion ... Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Crohn's disease and ...
A group of scientific experts assembled in London on October 23, 2013, to discuss the scope and appropriate use of the term " ... placebo-controlled trials". Lancet Infect Dis. 6 (6): 374-82. doi:10.1016/S1473-3099(06)70495-9. PMID 16728323.. ... Bridging the gap between consumers, green groups, and industry". Electronic Journal of Biotechnology. 9 (4): E49-55. doi: ... In addition, some groups of women respond to treatment based upon ethnicity, age, number of sexual partners, pregnancy, and the ...
A group of scientific experts assembled in London on October 23, 2013, to discuss the scope and appropriate use of the term ... placebo-controlled trials". Lancet Infect Dis. 6 (6): 374-82. doi:10.1016/S1473-3099(06)70495-9. PMID 16728323.. ... Bridging the gap between consumers, green groups, and industry". Electronic Journal of Biotechnology. 9 (4): E49-55. doi: ... This treatment is based on the observation that 70% of healthy females have a group of bacteria in the genus Lactobacillus that ...
Randomised, placebo-controlled trial". Br J Psych. 181: 22-28. doi:10.1192/bjp.181.1.22. PMID 12091259. Satia JA, Littman A, ... Patrick Lyn (December 1999). "Nutrients and HIV: part one -- beta carotene and selenium" (PDF). Altern Med Rev. 4 (6): 403-13. ... and some research groups continue to investigate whether it has an effect as a possible cancer treatment. In general, the ... and megavitamin therapies for a group of rare inborn errors of metabolism. A review in the Annals of Internal Medicine ...
It has two hydroxyl groups bonded to a benzene ring in a para position. It is a white granular solid. Substituted derivatives ... a randomized double-blind placebo-controlled trial". The British Journal of Dermatology. 173 (1): 209-217. doi:10.1111/bjd. ... Selenium disulfide (selenium sulfide). *Xenysalate. *Zinc pyrithione (pyrithione zinc). *Antihistamines. *Calcineurin ... Hydroquinone can lose a proton from both hydroxyl groups to form a diphenolate ion. The disodium diphenolate salt of ...
... some evidence suggests that athletes who take it are merely experiencing a placebo effect.[15] ... Compounds containing the sulfate group. H2SO4 He Li2SO4 BeSO4 B esters. ROSO3−. (RO)2SO2 (NH4)2SO4. [N2H5]HSO4. (NH3OH)2SO4. ...
EURODEM Incidence Research Group». Neurology. 53 (9): 1992-7. PMID 10599770. !CS1 manut: Nomes múltiplos: lista de autores ( ... A Randomised, Blinded, Placebo-Controlled Trial in Dementia Patients Continuing or Stopping Neuroleptics (The DART-AD Trial)». ... Loef M, Schrauzer GN, Walach H (2011). «Selenium and Alzheimer's disease: a systematic review». Journal of Alzheimer's Disease ... Placebo-controlled Phase I Trial». Lancet. 372 (9634): 216-23. PMID 18640458. doi:10.1016/S0140-6736(08)61075-2. !CS1 manut: ...
EURODEM Incidence Research Group. Neurology. 1999, 53 (9): 1992-97. PMID 10599770. doi:10.1212/wnl.53.9.1992 (英语).. ... Loef M, Schrauzer GN, Walach H. Selenium and Alzheimer's disease: a systematic review. Journal of Alzheimer's Disease (Review ... Placebo-controlled Phase I Trial. Lancet. 2008, 372 (9634): 216-23. PMID 18640458. doi:10.1016/S0140-6736(08)61075-2 (英语).. ... Guerreiro R, Wojtas A, Bras J; The Alzheimer Genetic Analysis Group; 等. TREM2 variants in Alzheimer's disease. The New England ...
A group of atoms in a molecule (e.g., CH2) may have multiple modes of oscillation caused by the stretching and bending motions ... 1873: Willoughby Smith discovered the photoconductivity of selenium.[56]. *1878: Samuel Pierpont Langley invents the first ... Hargate, G (2006). "A randomised double-blind study comparing the effect of 1072-nm light against placebo for the treatment of ... This can be used to gain information about the sample composition in terms of chemical groups present and also its purity (for ...
"Heart Group. Cochrane Database of Systematic Reviews. John Wiley & Sons (6): CD008684. doi:10.1002/14651858.CD008684.pub2 - via ... placebo-controlled study". Journal of Clinical Pharmacology. 33 (3): 226-229. doi:10.1002/j.1552-4604.1993.tb03948.x. PMID ... where Q refers to the quinone chemical group and 10 refers to the number of isoprenyl chemical subunits in its tail. ... Lipid and Blood Pressure Meta-analysis Collaboration Group. 90 (1): 24-34. doi:10.1016/j.mayocp.2014.08.021. PMID 25440725.. ...
Selenium Bromine Krypton Rubidium Strontium Yttrium Zirconium Niobium Molybdenum Technetium Ruthenium Rhodium Palladium Silver ... The Gale Group, Inc. Retrieved December 16, 2007.. *^ "Goddard-1926". NASA. Archived from the original on November 8, 2007. ... The pharmacological effect is doubted; a placebo effect is a more likely explanation.[105] Available studies support a ... Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group on the periodic ...
One group of researchers showed that corneal hypoxia exacerbated Pseudomonas binding to the corneal epithelium, internalization ... Later work that used these ChromaGen lenses with dyslexics in a randomised, double-blind, placebo controlled trial showed ... Lenses with covalently attached selenium molecules have been shown to reduce bacterial colonization without adversely affecting ... CLARE (contact lens associated red eye) is a group of inflammatory complications from lens wear ...
Selenium Bromine Krypton Rubidium Strontium Yttrium Zirconium Niobium Molybdenum Technetium Ruthenium Rhodium Palladium Silver ... The Gale Group, Inc. Retrieved December 16, 2007.. *^ "Goddard-1926". NASA. Archived from the original on November 8, 2007. ... The pharmacological effect is doubted; a placebo effect is a more likely explanation.[105] Available studies support a ... 2 concentration in the lungs helps to displace carbon monoxide from the heme group of hemoglobin.[92][93] Oxygen gas is ...
Volz HP, Kieser M (1997). "Kava-kava extract WS 1490 versus placebo in anxiety disorders--a randomized placebo-controlled 25- ... The "safe" hydrangeas belong to the Hydrangea serrata Amacha ("sweet tea") Cultivar Group.[17] ... Ayurvedic tea has also been found to contain nutrients including calcium, potassium, vanadium, iron, manganese, selenium and ...
Several studies have found Arnica montana to be no more effective than a placebo in relieving pain, swelling, and bruising. ... "Effect of homeopathic Arnica montana on bruising in face-lifts: results of a randomized, double-blind, placebo-controlled ... Robertson A, Suryanarayanan R, Banerjee A. "Homeopathic Arnica montana for post-tonsillectomy analgesia: a randomised placebo ... Iodine and Selenium *Journaling *Keeping Abreast of the News *Ketogenic Diet *Latissimus Dorsi Flap Surgery ...
... but not statistically significant increase in the number of cases of adult onset diabetes in men taking only selenium. Because ... and other institutes that comprise the National Institutes of Health shows that selenium and vitamin E supplements, taken ... independent review of study data from the Selenium and Vitamin E Cancer Prevention Trial (SELECT), funded by the National ... one took selenium and a vitamin E placebo; one took vitamin E and a selenium placebo; and the final group received placebos of ...
Selenium supplementation does not prevent diabetes and might actually precipitate it, a large prevention trial has suggested. ... there were 58 in the selenium group and 39 in the placebo group. Seleniums lack of beneficial effect on diabetes risk ... The selenium and placebo groups did not differ with respect to baseline characteristics. Overall, 97 new cases of type 2 ... although selenium-driven antioxidant activity plateaus at plasma selenium levels of 70 to 90 ng/mL. As a result, selenium ...
Selenium, a trace mineral found in grains, nuts and meats, and vitamin E whether taken alone or in combination do not prevent ... The participants were divided into four intervention groups: selenium, vitamin E, both selenium and vitamin E, and placebos. ... slightly increased risks of prostate cancer in the vitamin E group and type two diabetes mellitus in the selenium group. Both ... selenium group, trace mineral, type two diabetes, vitamin e ... Extra selenium can spur type-2 diabetes risk - Mar 01, 2012. ...
144 patients with cirrhosis will be randomized to one of 4 treatment groups, including a placebo. After treatement for 4 weeks ... It is possible that certain diseases result in selenium deficiency because of the form of selenium taken in the normal diet. ... We propose to measure the selenium biomarkers associated with supplemental intakes of 200 or 400 µg of selenium per day in the ... selenium supplements. selenate. selenomethionine. biomarkers. plasma selenium concentration. plasma glutathione peroxidase. ...
Selenium supplements appear to slow the progress of HIV, according to interim results of a study conducted here. ... Serum selenium concentration increased significantly in the selenium-treated group but not the placebo-treated group -- an ... 83 in the placebo group and 91 in the selenium group. ... Selenium "non-responders" did not differ from the placebo group ... As a result, the "non-responders" had selenium levels and HIV responses closer to the placebo group, Dr. Hurwitz and colleagues ...
Selenium, a trace mineral found in grains, nuts and meats, and vitamin E - whether taken alone or in combination - do not ... The participants were divided into four intervention groups: selenium, vitamin E, both selenium and vitamin E, and placebos. ... slightly increased risks of prostate cancer in the vitamin E group and type two diabetes mellitus in the selenium group. Both ... Selenium, a trace mineral found in grains, nuts and meats, and vitamin E - whether taken alone or in combination - do not ...
Only 11 percent of the placebo group showed signs of hair improvement. This indicates that saw palmetto is extremely effective ... Selenium. Selenium is a nutrient necessary for many of the bodys processes. As noted in case studies, individuals with low ... Wolff Group international conference. This research is not as boundless as it might first appear. Dr. Klenk is not the first ... Together with selenium, vitamin E works to prevent cell damage and hair loss from free radical damage. ...
... the risk estimate comparing the selenium supplemented with the placebo groups was used. Risk estimates from individual studies ... Selenium supplementation of children in a selenium-deficient area in China: blood selenium levels and glutathione peroxidase ... Serum selenium and risk of large size colorectal adenomas in a geographical area with a low selenium status. Am J Gastroenterol ... Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention ...
Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2011;306:1549-56. ... Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to ... Vitamin E increases prostate cancer risk in middle-aged men relative to placebo: no significant association observed with ... Vitamin E increases prostate cancer risk in middle-aged men relative to placebo: no significant association observed with ...
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to ... no significant association observed with selenium, either alone or in combination with vitamin E ... Vitamin E increases prostate cancer risk in middle-aged men relative to placebo: no significant association observed with ... Copyright © 2017 by BMJ Publishing Group Ltd & RCN Publishing Company Ltd.. 京ICP备15042040号-3 ...
... and the placebo groups. Serum selenium concentrations were measured before intervention. Findings On average 145 different ... The pre-treatment expression of the microRNAs did not differ between active treatment and the placebo groups. When comparing ... Background Selenium and coenzyme Q10 is essential for important cellular functions. A low selenium intake is reported from many ... or placebo for 4 years, 25 participants from each group were randomized and evaluated regarding levels of microRNA. Isolation ...
... compared selenium (200 mcg daily for 3 months) to placebo. Those in the selenium group reported improvements in their mood and ... 1,312 people were divided into two groups. One group received 200 mcg of yeast-based selenium daily; the other received placebo ... The results over two years failed to show benefit; both the placebo and the selenium group developed precancerous and cancerous ... fewer lung cancers as compared with the placebo group. (All these results were statistically significant.) Selenium-treated ...
... receiving selenium supplementation reported significantly better wellbeing in our trial compared with the placebo group, which ... Plasma selenium values were identical in both groups at study entry (127.4 ± 15.3 g/L group A; 129.2 ± 15.1 g/L group B). In ... there was no difference in selenium tissue concentration in selenium sufficient areas [30]. The selenium deficiency in our ... Improvement of ultrasound echogenicity was observed in all patients in group B versus ten patients in group A (. ). Evaluation ...
Selenium and Vitamin E in Preventing Cancer Progression and Recurrence in Patients With Early-Stage Bladder Cancer ... Arm II: Patients receive oral selenium tablet and oral placebo capsule once daily. - Arm III: Patients receive oral placebo ... Patients are stratified by recurrence risk group (high vs intermediate) and treatment center and randomized to 1 of 4 treatment ... Arm IV: Patients receive oral placebo tablet and oral placebo capsule once daily. In all arms, treatment continues for up to 5 ...
Two treatment groups: 60 mcg/day of selenium as selenium-enriched yeast or placebo yeast (60 mcg/day is the recommended intake ... The study will have two treatment groups: 60 mcg/day of selenium as selenium-enriched yeast or placebo (dummy) yeast (60 mcg/ ... Selenium in PRegnancy INTervention: a double-blind, randomised, placebo-controlled, two-group study ... The dose of selenium given is a nutritional dose and is the recommended intake of selenium for women. There are no risks of ...
There were 13 prostate cancer cases in the selenium-treated group and 35 cases in the placebo group (relative risk, RR=0.37, P= ... only four cases were diagnosed in the selenium-treated group and 16 cases were diagnosed in the placebo group after a 2 year ... the selenium-treated group had substantial reductions in the incidence of prostate cancer, and total cancer incidence and ... Although selenium shows no protective effects against the primary endpoint of squamous and basal cell carcinomas of the skin, ...
SELECT began in 2001 to test earlier research suggesting selenium and ...The paper which will appear in the October 12 edition ... The men were divided into four groups: vitamin E and Selenium; vitamin E alone; selenium alone; and placebo. The group taking ... The paper, which will appear in the October 12 edition of the Journal of the American Medical Association, found that a group ... The finding comes from a report summarizing the latest results of the Selenium and Vitamin E Cancer Prevention Trial (SELECT). ...
Selenium at Portsmouth Regional Hospital Supplement Forms/Alternate Names Selenite Selenomethionine Selenized Yeast Selenium ... compared selenium (200 mcg daily for 3 months) to placebo. Those in the selenium group reported improvements in their mood and ... One group received 200 mcg of yeast-based selenium daily; the other received placebo. Participants were not deficient in ... The results over two years failed to show benefit; both the placebo and the selenium group developed precancerous and cancerous ...
A more thorough evaluation of selenium supplementation is needed, to better understand its benefits to our immune system, and ... Groups of people with marginal selenium status, aged 50-64, were given selenium supplements, at different doses, to include in ... Others were given meals containing onions enriched with selenium. Other participants were given placebos, not containing ... Selenium deficiency has for a long time been associated with an impaired immune system. People with low levels of selenium have ...
The patients were divided into 4 groups and were given either levothyroxine, selenium, levothyroxine + selenium, or placebo. ... All three treatment groups of women, including those taking levothyroxine, levothyroxine + selenium or selenium-only, had the ... The group that took levothyroxine or levothyroxine + selenium had a reduction in TSH levels and increase in thyroid hormone ... At the start of the study, all groups of the Hashimotos patients had higher inflammatory markers than the group of healthy ...
E and selenium alone; a cholesterol-lowering drug plus niacin plus antioxidants; or a placebo. After three years of this ... They were divided into four groups and given: a cholesterol-lowering drug plus the vitamin, niacin; antioxidant vitamins A,C, ... And that antioxidants are no more effective than placebo in preventing heart attacks. ... and 100 micrograms of selenium (twice the recommended dosage). ... antioxidants were no better off than those who took placebos. ...
Compared with the placebo (referent group) in which 529 men developed prostate cancer, 620 men in the vitamin E group developed ... as did 575 in the selenium group (HR, 1.09; 99% CI, 0.93-1.27; p = 0.18), and 555 in the selenium plus vitamin E group (HR, ... The primary analysis included 34,887 men who were randomly assigned to one of four treatment groups: 8,752 to receive selenium ... Selenium, Dietary Supplements, Cardiovascular Diseases, Confidence Intervals, African Continental Ancestry Group, Prostatic ...
Find patient medical information for SELENIUM on WebMD including its uses, effectiveness, side effects and safety, interactions ... a placebo-controlled, double-blind clinical trial. Ebselen Study Group. Stroke 1998;29(1):12-17. View abstract. ... SELENIUM Uses & Effectiveness Likely Effective for:. *Selenium deficiency. Taking selenium by mouth is effective for preventing ... Selenium might thin the blood. Selenium might also increase the effects of warfarin in the body. Taking selenium along with ...
... selenium, vitamin E, selenium plus vitamin E, or placebo.15 Findings: 13 percent more prostate cancer for the vitamin E groups ... The Selenium and Vitamin E Cancer Prevention Trial (SELECT). A total of 35,533 men were assigned to one of four groups: ... Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention ... or placebo.17 Findings: There were 75% more deaths from fatal coronary artery disease in the beta-carotene groups and a slight ...
  • Randomised trials comparing patients with chronic asthma receiving selenium supplementation in conjunction with asthma medication, with patients taking asthma medication only. (cochrane.org)
  • In the U.S., the Eastern Coastal Plain and the Pacific Northwest have the lowest selenium levels. (webmd.com)
  • In preliminary reports, people with the lowest blood levels of selenium had between 3.8 and 5.8 times the risk of dying from cancer compared with those who had the highest selenium levels. (peacehealth.org)
  • And while evidence indicates that selenium levels decline with advancing age, 19,20 it is perhaps not surprising that when researchers studied a population of very long-lived people, they found the highest selenium levels in individuals over 100 years old. (lifeextension.com)
  • The most commonly used measures of selenium status are plasma and serum selenium concentrations [ 1 ]. (nih.gov)
  • We evaluated the association of serum selenium concentrations with fasting plasma glucose, glycosylated hemoglobin levels, and diabetes in the most recently available representative sample of the U.S. population. (pubmedcentralcanada.ca)
  • In U.S. adults, high serum selenium concentrations were associated with higher prevalence of diabetes and higher fasting plasma glucose and glycosylated hemoglobin levels. (pubmedcentralcanada.ca)
  • Vitamins B, C and E support immunity and selenium has been shown to reduce HIV replication in test tube studies. (aidsmap.com)
  • Subjects received either daily multivitamins (B vitamins and vitamins C and E), selenium alone, or multivitamins with selenium or placebo for 24 months. (nutraceuticalsworld.com)
  • The government-backed report by the Expert Group on Vitamins and Minerals (EVM) published last week "betrays an alarming level of bias" and "unhelpfully fails to discriminate between short-term and long-term use" according to Professor Arnold Beckett OBE BSc PhD DSc FRPharmS, one of the country's leading pharmacists and former President of the Royal Pharmaceutical Society. (positivehealth.com)
  • Consistent with previous studies, we observed no protective effect of selenium on colorectal cancer among women. (aacrjournals.org)
  • The current evidence from in vitro and animal studies strongly supports a protective effect of selenium on colorectal cancer, whereas the evidence from clinical trials and observational studies is inconclusive ( 1-15 ). (aacrjournals.org)
  • Many observational studies ( 1-9 ), but not all ( 10-15 ), support a protective effect of selenium on risk of colorectal tumors. (aacrjournals.org)
  • one reported no preventive effect of selenium against stomach, colorectal, oesophageal or lung cancer. (cam-cancer.org)
  • The researchers conducted randomized, placebo-controlled and double blind trials. (thaindian.com)
  • Given the challenges of using conventional pharmacotherapy to achieve and maintain virologic suppression," the researchers concluded, "our results support the use of selenium as a simple, inexpensive and safe adjunct therapy. (medpagetoday.com)
  • The exact mechanism by which selenium exerts its effects on HIV-1 viral replication is not known," the researchers said. (medpagetoday.com)
  • After adjusting their statistics so they wouldn't be thrown off by various factors, the researchers reported that those who took the combination were about half as likely to show signs over two years that their infection had progressed toward AIDS as those who took the placebo. (medicinenet.com)
  • Researchers recently divided rabbits into two groups. (secondopinionnewsletter.com)
  • Researchers in Sweden reported last year on over 400 healthy persons over age 70 who were given CoQ10 and another nutrient selenium or matching placebo pills. (mindbodygreen.com)
  • Therefore, even mild selenium deficiency may contribute to the development and maintenance of autoimmune thyroid diseases. (hindawi.com)
  • Research shows that taking 200 mcg of selenium daily along with thyroid hormone might decrease antibodies in the body that contribute to this condition. (webmd.com)
  • Via its incorporation into more than two dozen selenoproteins throughout the body, 2,3 selenium provides potent defense against cancer-causing DNA damage , 4,5 facilitates removal of dangerous toxins from the body, 6 supports optimal thyroid function, 7 maintains immune system activity, 3,8,9 and much more. (lifeextension.com)
  • The effects of endocrine disruptors and nutraceuticals and over-the-counter products (selenium, L-carnitine, thyroid hormones, iodine, and biotin) will also be discussed. (springer.com)
  • Concentrations in blood and urine reflect recent selenium intake. (nih.gov)
  • As a result, selenium concentrations in plant-based foods vary widely by geographic location [ 1 , 2 ]. (nih.gov)
  • The difference in blood concentrations of omega-3 fatty acids between the lowest and highest risk groups was about 2.5 percentage points (3.2 percent vs. 5.7 percent), which is somewhat larger than the effect of eating salmon twice a week, Kristal said. (scienceblog.com)
  • We evaluated the association of serum selenium, measured by inductively coupled plasma-dynamic reaction cell-mass spectrometry, and diabetes, defined as a self-report of current use of hypoglycemic agents or insulin or as fasting plasma glucose ≥ 126 mg/dL. (pubmedcentralcanada.ca)