An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
Diagnostic aid in pancreas function determination.
An enzyme catalyzing the oxidation of 2 moles of glutathione in the presence of hydrogen peroxide to yield oxidized glutathione and water. EC
Selenoproteins are proteins that specifically incorporate SELENOCYSTEINE into their amino acid chain. Most selenoproteins are enzymes with the selenocysteine residues being responsible for their catalytic functions.
An extracellular selenoprotein that contains most of the SELENIUM in PLASMA. Selenoprotein P functions as an antioxidant and appears to transport selenium from the LIVER to peripheral tissues.
Organic compounds which contain selenium as an integral part of the molecule.
A strong dibasic acid with the molecular formula H2SeO4. Included under this heading is the acid form, and inorganic salts of dihydrogen selenium tetraoxide.
Unstable isotopes of selenium that decay or disintegrate emitting radiation. Se atoms with atomic weights 70-73, 75, 79, 81, and 83-85 are radioactive selenium isotopes.
A selenium compound with the molecular formula H2SO3. It used as a source of SELENIUM, especially for patients that develop selenium deficiency following prolonged PARENTERAL NUTRITION.
A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid.
Inorganic compounds formed through the oxidation of selenium.
The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.
A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
A group of proteins that covalently attach to selenium or SELENIUM-containing compounds.
A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC
Regular course of eating and drinking adopted by a person or animal.
The dry cells of any suitable strain of SACCHAROMYCES CEREVISIAE or CANDIDA. It can be obtained as a by-product from the brewing of beer or by growing on media not suitable for beer production. Dried yeast serves as a source of protein and VITAMIN B COMPLEX.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
Spectrophotometric techniques by which the absorption or emmision spectra of radiation from atoms are produced and analyzed.
A single SELENOCYSTEINE containing protein that binds reduced GLUTATHIONE and can act as an antioxidant.
Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)
A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)
A myodegeneration most frequent in calves and lambs whose dams have been fed during gestation or longer on feeds, especially legumes (FABACEAE), grown in certain areas where selenium is either deficient or unavailable in the soil. It has been recorded in many countries. It has been produced experimentally in several species of animals on low-selenium intake. A similar myopathy occurs naturally in goats, deer, foals, and dogs but proof of the etiology is lacking. (Merck Veterinary Manual, 5th ed)
State of the body in relation to the consumption and utilization of nutrients.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A mitosporic fungal genus that causes a variety of skin disorders. Malassezia furfur (Pityrosporum orbiculare) causes TINEA VERSICOLOR.
A mild exanthematous inflammation of unknown etiology. It is characterized by the presence of salmon-colored maculopapular lesions. The most striking feature is the arrangement of the lesions such that the long axis is parallel to the lines of cleavage. The eruptions are usually generalized, affecting chiefly the trunk, and the course is often self-limiting.
Drugs whose drug name is not protected by a trademark. They may be manufactured by several companies.
A name originally applied to a group of skin diseases characterized by the formation of fine, branny scales, but now used only with a modifier. (Dorland, 27th ed)
Disabling osteochondrodysplasia with OSTEOSCLEROSIS, cone-shaped METAPHYSIS, and shortening of the DIAPHYSIS. It is endemic in parts of Siberia and northern China. Mineral deficiencies (e.g., selenium, iodine), fungal cereal contamination, and water contamination may be contributing factors in its etiology.
An autonomous region located in central Asia, within China.
A heterogeneous group of infections produced by coxsackieviruses, including HERPANGINA, aseptic meningitis (MENINGITIS, ASEPTIC), a common-cold-like syndrome, a non-paralytic poliomyelitis-like syndrome, epidemic pleurodynia (PLEURODYNIA, EPIDEMIC) and a serious MYOCARDITIS.
Sequential operating programs and data which instruct the functioning of a digital computer.
Locomotor behavior not involving a steering reaction, but in which there may be a turning random in direction. It includes orthokinesis, the rate of movement and klinokinesis, the amount of turning, which are related to the intensity of stimulation.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
A class of lymphocytes characterized by the lack of surface markers specific for either T or B lymphocytes.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
The portion of an interactive computer program that issues messages to and receives commands from a user.
The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.
Specific languages used to prepare computer programs.
An operation for the continuous emptying of ascitic fluid into the venous system. Fluid removal is based on intraperitoneal and intrathoracic superior vena cava pressure differentials and is performed via a pressure-sensitive one-way valve connected to a tube traversing the subcutaneous tissue of the chest wall to the neck where it enters the internal jugular vein and terminates in the superior vena cava. It is used in the treatment of intractable ascites.
Controlled operation of an apparatus, process, or system by mechanical or electronic devices that take the place of human organs of observation, effort, and decision. (From Webster's Collegiate Dictionary, 1993)
Controlled operations of analytic or diagnostic processes, or systems by mechanical or electronic devices.
Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.
An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)

Infleuce of dietary levels of vitamin E and selenium on tissue and blood parameters in pigs. (1/2336)

Eighteen barrows approximately three weeks of age were used in a 3 X 3 factorial arrangement to investigate the effect of level of supplemental vitamin E and selenium on tissue and blood parameters. Tissue selenium concentrations increased in a quadratic manner with increased selenium intake with kidney tissue containing considerably greater concentrations than liver, heart or muscle. Supplementation of the diet caused a three-fold increase in serum selenium within the first week with a slight tendency to further increases in subsequent weeks. Serum vitamin E of unsupplemented pigs declined by fifty percent during the experiment, whereas supplemental vitamin E resulted in increased serum vitamin E. There was a considerable viration in percent peroxide hemolysis. Correlation of -0.63 between percent peroxide hemolysis and vitamin E intake and -0.85 between percent peroxide hemolysis and serum vitamin E were observed.  (+info)

A family of S-methylmethionine-dependent thiol/selenol methyltransferases. Role in selenium tolerance and evolutionary relation. (2/2336)

Several plant species can tolerate high concentrations of selenium in the environment, and they accumulate organoselenium compounds. One of these compounds is Se-methylselenocysteine, synthesized by a number of species from the genus Astragalus (Fabaceae), like A. bisulcatus. An enzyme has been previously isolated from this organism that catalyzes methyl transfer from S-adenosylmethionine to selenocysteine. To elucidate the role of the enzyme in selenium tolerance, the cDNA coding for selenocysteine methyltransferase from A. bisulcatus was cloned and sequenced. Data base searches revealed the existence of several apparent homologs of hitherto unassigned function. The gene for one of them, yagD from Escherichia coli, was cloned, and the protein was overproduced and purified. A functional analysis showed that the YagD protein catalyzes methylation of homocysteine, selenohomocysteine, and selenocysteine with S-adenosylmethionine and S-methylmethionine as methyl group donors. S-Methylmethionine was now shown to be also the physiological methyl group donor for the A. bisulcatus selenocysteine methyltransferase. A model system was set up in E. coli which demonstrated that expression of the plant and, although to a much lesser degree, of the bacterial methyltransferase gene increases selenium tolerance and strongly reduces unspecific selenium incorporation into proteins, provided that S-methylmethionine is present in the medium. It is postulated that the selenocysteine methyltransferase under selective pressure developed from an S-methylmethionine-dependent thiol/selenol methyltransferase.  (+info)

Selenium redox biochemistry of zinc-sulfur coordination sites in proteins and enzymes. (3/2336)

Selenium has been increasingly recognized as an essential element in biology and medicine. Its biochemistry resembles that of sulfur, yet differs from it by virtue of both redox potentials and stabilities of its oxidation states. Selenium can substitute for the more ubiquitous sulfur of cysteine and as such plays an important role in more than a dozen selenoproteins. We have chosen to examine zinc-sulfur centers as possible targets of selenium redox biochemistry. Selenium compounds release zinc from zinc/thiolate-coordination environments, thereby affecting the cellular thiol redox state and the distribution of zinc and likely of other metal ions. Aromatic selenium compounds are excellent spectroscopic probes of the otherwise relatively unstable functional selenium groups. Zinc-coordinated thiolates, e.g., metallothionein (MT), and uncoordinated thiolates, e.g., glutathione, react with benzeneseleninic acid (oxidation state +2), benzeneselenenyl chloride (oxidation state 0) and selenocystamine (oxidation state -1). Benzeneseleninic acid and benzeneselenenyl chloride react very rapidly with MT and titrate substoichiometrically and with a 1:1 stoichiometry, respectively. Selenium compounds also catalyze the release of zinc from MT in peroxidation and thiol/disulfide-interchange reactions. The selenoenzyme glutathione peroxidase catalytically oxidizes MT and releases zinc in the presence of t-butyl hydroperoxide, suggesting that this type of redox chemistry may be employed in biology for the control of metal metabolism. Moreover, selenium compounds are likely targets for zinc/thiolate coordination centers in vivo, because the reactions are only partially suppressed by excess glutathione. This specificity and the potential to undergo catalytic reactions at low concentrations suggests that zinc release is a significant aspect of the therapeutic antioxidant actions of selenium compounds in antiinflammatory and anticarcinogenic agents.  (+info)

Effects of pre- or postpartum selenium supplementation on selenium status in beef cows and their calves. (4/2336)

The effect of Se supplementation before or after calving on Se status in deficient cows and their calves was studied using 72 beef cows in two experiments. In Exp. 1, cows calving in February or March 1997 were supplemented orally for 15 d in late pregnancy with 13.0, 32.5, or 45.5 mg of Se/d as sodium selenite. Glutathione peroxidase (GSH-Px) activities were measured in red blood cells (RBC) or plasma of cows and calves at d 15 and between d 17 and 88 after calving. In Exp. 2, cows calving in January 1997 were supplemented orally with .0, 13.0, or 32.5 mg of Se/d for 15 d postpartum, and calves were injected with 1.38 mg of Se when 2 d old and at an average age of 49 d. The GSH-Px activities were measured in 30-d-old calves and in cows and calves between d 77 and 115 after calving. In both experiments, Se supplementation resulted in adequate Se status for the dams. The increase in RBC GSH-Px activity was faster with 45.5 mg of Se/d, and GSH-Px activities remained high for up to 98 d after the end of supplementation. The improvement in Se status in calves as a result of maternal supplementation was greater in Exp. 1 than in Exp. 2, suggesting that the placental transfer of Se is more efficient than milk transfer. Prepartum oral Se supplementation of deficient beef cows with 13.0 mg of Se/d for 15 d allowed adequate Se status of dams and calves, and 45.5 mg of Se/d resulted in a faster improvement of Se status. Parenteral administration of 1.38 mg of Se to newborn calves did not sustain normal Se status in calves issued from deficient cows.  (+info)

Selenium toxicosis in a flock of Katahdin hair sheep. (5/2336)

Selenium supplementation by injection is a common practice. Acute toxicosis from dosaging errors may occur. In this report, 23 of 56 ewes and all 24 lambs injected with selenium died. Tissue, whole blood, and serum concentrations aided in the diagnosis. Caution should be taken when supplementing selenium by injection.  (+info)

The role of humic substances in drinking water in Kashin-Beck disease in China. (6/2336)

We conducted in vitro and in vivo assays in a selenium-deficient system to determine if organic matter (mainly fulvic acid; FA) is involved in a free radical mechanism of action for Kashin-Beck disease. Cartilage cell culture experiments indicated that the oxy or hydroxy functional groups in FA may interfere with the cell membrane and result in enhancement of lipid peroxidation. Experiments with rats demonstrated that toxicity from FA was reduced when the hydroxy group was blocked. Induction of lipid peroxidation by FA in liver and blood of rats was similar to that exhibited by acetyl phenyl hydrazine. FA accumulated in bone and cartilage, where selenium rarely concentrates. In addition, selenium supplementation in rats' drinking water inhibited the generation of oxy-free radicals in bone. We hypothesized that FA in drinking water is an etiological factor of Kashin-Beck disease and that the mechanism of action involves the oxy and hydroxy groups in FA for the generation of free radicals. Selenium was confirmed to be a preventive factor for Kashin-Beck disease.  (+info)

Biotransformation of methylmercury in vitro. (7/2336)

Inorganic mercury formation from methylmercury by the mouse liver and kidney was studied in vitro. With chopped liver or kidney, inorganic mercury was formed from added methylmercury, but when the tissue was homogenized, the activity was diminished. Equimolar addition of selenium had no effect on the reaction.  (+info)

The retention and distribution by healthy young men of stable isotopes of selenium consumed as selenite, selenate or hydroponically-grown broccoli are dependent on the isotopic form. (8/2336)

Twenty-seven healthy young men were randomly assigned to diets that supplied low (32.6 microg/d) or high (226.5 microg/d) levels of selenium for a 105-d study. After consuming the diets for 85 d, subjects were fed a test meal that contained 74Se in the form of selenite or selenate and 82Se incorporated into hydroponically-raised broccoli. Urine, fecal and blood samples were collected daily. Isotope absorption was not different (P > 0.05) for selenate and Se in broccoli; Se absorption from selenite was highly variable and was not included in statistical analyses. Significantly more isotope was absorbed by subjects fed the high Se diet (P = 0. 015). Urinary isotope excretion was greater when selenate was fed than when broccoli was fed (P = 0.0001), and consequently more Se from broccoli (as compared to selenate) was retained (59.2 +/- 2.4 and 36.4 +/- 4.6% for Se in broccoli and selenate, respectively; P = 0.0001). Despite the higher retention, less isotope from broccoli than from selenate was present in the plasma. Plasma proteins separated by gel permeation chromatography showed that most of the isotopes were distributed between two medium molecular weight peaks. Less isotope was found in plasma proteins of subjects fed the high Se diet, but the form of Se had no effect on isotope distribution. These results show that dietary Se intake alters the retention of stable isotopes of Se and that humans retain and distribute Se from broccoli in a different manner than Se from inorganic salts.  (+info)

OBJECTIVE. Recent studies have reported that antioxidant status, including serum selenium concentrations, is altered in women who develop preeclampsia. We wished to examine the effects of selenium supplementation in the prevention of preeclampsia in high-risk pregnant women.. DESIGN. We carried out a randomized, double-blind, placebo-controlled pilot trial. A total of 166 primigravid pregnant women, who were in the first trimester of pregnancy, were randomized to receive 100 microg of selenium (n = 83; dropouts, n = 22) or a placebo (n = 83; dropouts, n = 19) per day until delivery. The incidence of preeclampsia, serum selenium concentrations, lipid profile and high-sensitivity C-reactive protein status were evaluated at baseline and at the end of the study.. RESULTS. Supplementation with selenium was not associated with any reported major side effects and was associated with a significant increase in mean serum selenium concentrations at term (p , 0.001). In contrast, mean serum selenium ...
During an almost seven-year follow-up period, elderly healthy Swedish citizens with low serum selenium concentrations had significantly increased cardiovascular mortality and total mortality rates compared to contemporaries with higher serum selenium concentrations. Specifically, there was a 56% increased risk for cardiovascular mortality and a 43% increased risk for all-cause mortality. Accordingly, the Swedish researchers suggested that selenium supplementation should be recommended to all Swedish citizens with a serum selenium concentration below 57 micrograms per liter [Alehagen 2016].. In fact, Professor Urban Alehagen and his team of researchers at Linköping University pointed out that the average serum selenium concentrations observed in the study of elderly Swedish citizens - 67.1 micrograms per liter - is not sufficient to achieve optimal function of the important selenoproteins that require selenium as a component [Alehagen 2016]: read more ...
Low serum selenium has been associated with lower CD4 counts and greater mortality among HIV-1-seropositive individuals, but most studies have not controlled for serum albumin and the presence of an acute phase response. A cross-sectional study was conducted to evaluate relationships between serum selenium concentrations and CD4 count, plasma viral load, serum albumin, and acute phase response markers among 400 HIV-1-seropositive women. In univariate analyses, lower CD4 count, higher plasma viral load, lower albumin, and the presence of an acute phase response were each significantly associated with lower serum selenium concentrations. In multivariate analyses including all four of these covariates, only albumin remained significantly associated with serum selenium. For each 0.1 g/dl increase in serum albumin, serum selenium increased by 0.8 μg/l (p < 0.001). Women with an acute phase response also had lower serum selenium (by 5.6 μg/l, p = 0.06). Serum selenium was independently associated with serum
Selenium is a trace mineral that incorporates itself into proteins, making the proteins into antioxidant enzymes. These enzymes aid the body in fighting cellular damage from free radicals. Our selenium is in an amino acid form L-selenomethionine, which research indicates is better absorbed and more bioavailable compared to other forms of selenium.* Serving Size: 1 capsule Vitamin C (as Ascorbic Acid and Ascorbyl Palmitate) 250 mg Selenium (as L-Selenomethionine) 200 mg Other Ingredients: Vegetarian cellulose capsule. Directions: One capsule daily with a meal as a dietary supplement, or as directed by a Doctor.
PubMed journal article Selenium supplementation enhances low selenium levels and stimulates glutathione peroxidase activity in peripheral blood and distal colon mucosa in past and present carriers of colon adenoma were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
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Selenium can be found in two different forms: inorganic and organic. Both can be absorbed by the body and used to increase selenium in our body, but studies appear when it comes to organic vs inorganic selenium, organic may be more bioavailable.. There hasnt been a lot of study in human with regards to comparing the bioavailability and assimilation of selenium from inorganic and organic selenium, but there has been a lot of animal research conducted.. In one study on cows, Se-enriched yeast was found to be much more effective in raising the concentration of selenium in the blood, colostrum, and milk. It also significantly boosted glutathione activity which is important to reduce oxidative stress. [3]. In another study on sheep, supranutritional supplementation of Se-yeast (organic selenium) was found to be more effective than Na-selenite at raising whole blood concentration in a dose-dependent manner. Whereas there was no difference between increasing doses for the inorganic selenium group. ...
Some studies have suggested that people with higher selenium levels have a lower risk of certain types of cancer; a review conducted by the Cochrane Collaboration, however, found no clear evidence that selenium supplements provide a cancer benefit.. Selenium is a trace mineral that is important for human health. Small amounts are generally sufficient, and excess selenium may be harmful. Meats and breads are common sources of selenium in the United States.[1] Selenium may also be taken as a supplement.. Some studies have suggested that selenium-an antioxidant-may reduce the risk of certain types of cancer, such as prostate cancer and bladder cancer. Others studies, however, failed to find a benefit.. To summarize the available evidence, researchers evaluated 55 studies that involved a total of more than one million participants.[2] The studies with the most reliable results found that selenium supplements did not reduce the risk of prostate cancer or non-melanoma skin cancer.. The researchers ...
Background: Increasing evidence support the role of oxidative stress in the development of Primary hypertension (HTN). Selenium is an essential micronutrient with antioxidant properties mediated via selenoenzymes like glutathione peroxidases. It is hypothesized that selenium plays a role in blood pressure regulation and HTN prevention. We conducted a meta-analysis to evaluate the relationship between circulating selenium levels and HTN.. Methods: We searched MEDLINE, CINAHL and COCHRANE databases for studies reporting serum selenium levels in the patients with HTN and healthy controls. We calculated the weighted standardized mean difference (SMD) in the serum selenium levels between the HTN and control groups.. Results: Our search strategy yielded 313 articles and we included 10 studies enrolling 10420 participants. The median age of the HTN group was 57 yrs. (IQR 56-58) compared to 46 yrs. (IQR 42-50) in the control group. The median body mass index (BMI) in the HTN group was 28 kg/m2 (IQR ...
Citation: Taylor, J.B. 2005. Time-dependent influence of supranutritional organically bound selenium accumlation in growing wether lambs. Journal of Animal Science. 83:1186-1193. Interpretive Summary: Opportunities to supplement selenium to grazing sheep are sometimes limited in extensive North America range sheep operations. Feeding growing wethers 2.9 ug selenium/g dry matter, as high selenium wheat grain, increases the amount of selenium deposited in the body within 14 days, and enhances skeletal muscle selenium six-fold within 56 days. The strategic use of high selenium wheat grain to deliver supranutritional selenium levels, provides a readily available source of selenomethionine, and rapidly increases tissue selenium levels in wether lambs without adversely influencing performance. Such a selenium supplementation strategy could provide sheep with an endogenous selenium source during periods of inadequate selenium intake, and increase the selenium content of retail skeletal muscle products. ...
Aim: The aim of the study was to compare selenium levels in plasma and aqueous humour in subjects with and without primary open-angle glaucoma (POAG).. Methods: Forty-seven POAG cases and 54 controls in this case-control study were recruited from surgery patients at the University Physicians Ophthalmology Clinic in Tucson, Arizona, USA. Aqueous humour and plasma selenium were determined by high-performance liquid chromatography ion channel plasma mass spectrometry (HPLC ICP-MS). Potential confounders were assessed via a questionnaire. Biological samples were collected and processed at surgery and analysed for selenium content after collection was complete. Outcome measures included the odds of glaucoma in relationship to plasma selenium, aqueous humour selenium, and the ratio of levels of aqueous humour selenium to plasma selenium.. Results: Tertile of selenium and its relationship to POAG was examined. After adjustment for common glaucoma risk factors, the odds of glaucoma in the highest ...
Selenium is an essential nutrient that plays a role in oxidant defense, among other functions. There is much interest in the role selenium may play in several disease processes. It is possible that certain diseases result in selenium deficiency because of the form of selenium taken in the normal diet.. We propose to measure the selenium biomarkers associated with supplemental intakes of 200 or 400 µg of selenium per day in the chemical form selenate, or with supplemental intake of 200 µg selenium as selenomethionine. 144 patients with cirrhosis will be randomized to one of 4 treatment groups, including a placebo. After treatement for 4 weeks, all participants will receive 400 µg of selenium per day as selenate for 4 weeks. Blood will be measured initially and at 4 and 8 weeks. Selenium, selenoprotein P and glutathione peroxidase will be measured in the plasma. ...
Selenium is an essential nutrient that plays a role in oxidant defense, among other functions. There is much interest in the role selenium may play in several disease processes. It is possible that certain diseases result in selenium deficiency because of the form of selenium taken in the normal diet.. We propose to measure the selenium biomarkers associated with supplemental intakes of 200 or 400 µg of selenium per day in the chemical form selenate, or with supplemental intake of 200 µg selenium as selenomethionine. 144 patients with cirrhosis will be randomized to one of 4 treatment groups, including a placebo. After treatement for 4 weeks, all participants will receive 400 µg of selenium per day as selenate for 4 weeks. Blood will be measured initially and at 4 and 8 weeks. Selenium, selenoprotein P and glutathione peroxidase will be measured in the plasma. ...
Global High Selenium Yeast Market to Reach $331. 6 Million by 2027. Amid the COVID-19 crisis, the global market for High Selenium Yeast estimated at US$291. 8 Million in the year 2020, is projected to reach a revised size of US$331.New York, Aug. 21, 2020 (GLOBE NEWSWIRE) -- announces
Selenium Levels Linked to Risk of Epilepsy. The January 2007 Pediatric Neurology published an article on selenium and epilepsy. In it, 80 patients who met the criteria of intractable epilepsy were compared to a normal control group of the same age, socioeconomic level and place of living. Serum selenium levels were significantly lower in the patient group compared to the control group. Selenium is known as a micro-mineral beneficial for immune and cardiovascular function, but it may be a brain-protective nutrient as well. Selenium boosts antioxidant levels and studies indicate antioxidants are important to protect neurons in the brain. The RDA is way too low for selenium. 200 to 400 mcg per day may be more effective based on the best studies.. Spource: Ashrafi MR, Shabanian R, Abbaskhanian A, Nasirian A, Ghofrani M, Mohammadi M, Zamani GR, Kayhanidoost Z, Ebrahimi S, Pourpak Z. Selenium and Intractable Epilepsy: Is There Any Correlation? Pediatr Neurol. 2007 Jan;36(1):25-29. ...
Three forms of selenium + vitamin E. Selenium is available in several different forms. Each form of selenium acts along a different pathway to support healthy cell division. For optimized selenium support, one should supplement with all three forms of selenium.. Super Selenium Complex delivers sodium selenite, L-selenomethionine, and selenium-methyl L-selenocysteine. Super Selenium Complex also contains a small amount of vitamin E because it has been shown to work synergistically with selenium.1 Antioxidant, thyroid, and immune support. Selenium is also an important factor when it comes to its ability to fight one of the primary causes of premature aging: oxidative damage. Thats because the body utilizes selenium to make glutathione peroxidase, an endogenous antioxidant enzyme. Selenium also supports normal thyroid and immune function in healthy individuals.. Cardiovascular health, brain health, and healthy cell division. Selenium plays a role in healthy cell division. But its ability to ...
The present view is that selenium metabolites (i.e., methylated forms of selenium), rather than simply the saturation of L-selenocysteine synthesis alone, is a key factor in seleniums cancer-preventive effects.5 At physiological levels of intake, dietary selenium (inorganic and organic) is reduced to hydrogen selenide (H2Se). From H2Se, selenium is phosphorylated and incorporated into proteins such as L-selenocysteine. During periods of supraphysiological intake (supplementation), once L-selenocysteine levels are saturated, H2Se is rapidly methylated to dimethyl selenide and other methylated forms, including the monomethylated and trimethylselenonium forms. Experimental studies highlight that these methylated forms of selenium (metabolites) possess direct and indirect chemopreventive effects that are not attainable by the action of glutathione peroxidase acting alone. Thus, selenium supplementation (100-400 mcg per day) increases the levels of methylated selenium metabolites that appear to ...
Getting back to selenium form, what could be the possible biochemical differences between selenomethionine and high-selenium yeast at the cellular level?. Whitacre: We and many other selenium experts believe that the SELECT study should have included the standardized high-selenium yeast, which has been found effective in reducing cancer risk in animal studies and human clinical trials. High-selenium yeast is different from the single synthetic amino acid compound, selenomethionine, used in the SELECT study. High-selenium yeast contains several different natural anabolic and catabolic forms of organically bound selenium in addition to selenomethionine such as selenocysteine, methylselenocysteine and several other selenium compounds, all organically bound. We suspect that the advantage of high-selenium yeast lies in its content of multiple forms of selenium, including some forms that are more effective than selenomethionine in anti-carcinogenesis.. More importantly, current research at Penn State ...
Super Selenium Complex 200 mcg Vitamin E by Life Extension 100 VegCap Super Selenium Complex 200 mcg Vitamin E 100 VegCap Super Selenium Complex with a new selenium blend that combines all three of these unique forms of selenium. A small amount of vitamin E is included because it has been shown to work synergistically with selenium.1 Caution If you are taking anti-coagulant or anti-platelet medications or have a bleeding disorder consult your healthcare provider before taking this product. Suggested Use As a dietary supplement Take one capsule per day with food - Or as directed by your healthcare professional. Supplement Facts Serving Size 1 vegetarian capsule Amount Per Serving Daily Value Vitamin E (as D-alpha tocopheryl succinate) 30 IU Selenium (as Se-Methyl L-Selenocysteine SelenoPure1 L-selenomethionine sodium selenite) 200 mcg (Selenium (L-selenomethionine1) 50 mcg) (Selenium (sodium selenite) 50 mcg) (Selenium (Se-Methyl L-Selenocysteine) 100 mcg) Percent Daily Values are ...
We investigated the efficacy of Brazil nuts in increasing selenium status in comparison with selenomethionine. Participants consumed 2 Brazil nuts thought to provide approximately 100 mug Selenium, 100 mug Selenium as selenomethionine, or placebo daily for 12 wk. Actual intake from nuts averaged 53 mug Selenium /d (possible range: 20-84 mug Se). Plasma selenium and plasma and whole blood glutathione peroxidase activities were measured at baseline and at 2, 4, 8, and 12 wk, and effects of treatments were compared. Plasma selenium increased by 64%, 61%, and 7%; plasma glutathione peroxidase by 8%, 3%, and -1%; and whole blood glutathione peroxidase by 13%, 5%, and 1.9% in the Brazil nut, selenomethionine, and placebo groups, respectively. Consumption of 2 raw Brazil nuts daily is as effective for increasing selenium status and enhancing glutathione peroxidase activity as 100 mug Se as selenomethionine. Inclusion of this high-selenium food in the diet could avoid the need for fortification or ...
Selenium is particularly concentrated in the alkaline soils of the drier regions of the world. In the Great Plains region of the U.S., plants absorb selenium from the soil in quantities sufficient to poison grazing livestock. Selenium poisoning may have been a critical factor in the delay of the cavalry scheduled to relieve General Custer at the Battle of the Little Big Horn in Montana. A peculiar sickness developed in the horses traveling through what are now known to be high selenium regions.. Selenium deficiency in livestock, however, is far more common than toxicity. It can cause poor growth, degenerative muscle disease, and reproductive failures, such as difficulty in conceiving and birth of premature, weak, and stillborn young. Selenium-deficiency diseases have been economically significant problems in areas of the world where the soil levels of selenium available for uptake by plants are low. Many livestock managers provide selenium supplements for their animals.. Both natural and ...
TY - JOUR. T1 - Selenium content of wheat for breadmaking in Scotland and the relationship between gluathione peroxidase (EC1.11.1.9) levels in whole blood and bread consumption.. AU - Barclay, MNI. AU - MacPherson, A. PY - 1992. Y1 - 1992. KW - Blood. KW - Consumption. KW - Content. KW - Level. KW - Peroxidase. KW - Relationship. KW - Scotland. KW - Selenium. KW - Selenium Content. KW - Wheat. M3 - Article. VL - 68. SP - 261. EP - 270. JO - British Journal of Nutrition. JF - British Journal of Nutrition. SN - 0007-1145. ER - ...
The selenium content of normal adult humans can vary widely. Values from 3mg in New Zealanders to 14mg in some Americans reflect the profound influence of the natural environment on the selenium contents of soils, crops, and human tissues.
Selenium is an essential element in human diets but the risk of suboptimal intake increases where food choices are narrow. Here we show that suboptimal dietary intake (i.e. 20-30 µg Se person(-1) d(-1)) is widespread in Malawi, based on a spatial integration of Se concentrations of maize (Zea mays L.) grain and soil surveys for 88 field sites, representing 10 primary soil types and |75% of the national land area. The median maize grain Se concentration was 0.019 mg kg(-1) (range 0.005-0.533), a mean intake of 6.7 µg Se person(-1) d(-1) from maize flour based on national consumption patterns. Maize grain Se concentration was up to 10-fold higher in crops grown on soils with naturally high pH (|6.5) (Eutric Vertisols). Under these less acidic conditions, Se becomes considerably more available to plants due to the greater solubility of Se((IV)) species and oxidation to Se((VI)).
sure, high blood sugar, obesity and high cholesterol is called metabolic syndrome and when these conditions occur together, they dramatically increase your risk of heart disease, stroke and Type 2 diabetes. In a study of 2,069 patients, dietary selenium intake had a moderate negative association with metabolic syndrome. In a study of 501 British volunteers aged 60 to 74 years, supplementation with sele- nium (100 mcg, 200 mcg, 300 mcg) showed progressive decreases in total cholesterol profiles for those with low selenium levels, but cautions that those with already high selenium intake might be adversely affected by extra selenium supplementation. In a 12-year follow-up of a group ...
Here are some REAL customer reviews:. I love it and I know you will too!! =). I have a few supplements I have been taking together to help boost my mood, energy, health boost and more. These Selenium supplement pills are for antioxidants and I needed the boost. I donate plasma religiously and definitely need the boost. I have 2…Read more. Selenium. Rice flour, vegetable cellulose, vegetable magnesium stearate and silicon dioxide is what it contains. Selenium has attracted attention because of its antioxidant properties. Antioxidants protect cells from damage. Evidence that selenium supplements may…Read more. Anti-oxidents to maintain a heathy lifestyle!. I have been using several of the Nutrissa brand products for a while now and I do like them. What I have found about Selenium is that it is not something your body makes on its own. Its something you have to take. When your body is lacking this mineral,…Read more. ...
Infante, HG, OConnor, G, Rayman, M, Wahlen, R, Spallholz, JE, Hearn, R and Catterick, T (2005) Identification of water-soluble gamma-glutamyl-Se-methylselenocysteine in yeast-based selenium supplements by reversed-phase HPLC with ICP-MS and electrospray tandem MS detection In: European Winter Conference on Plasma Spectrochemisty, 2005-01-30 - 2005-02-03, Budapest, HUNGARY. Full text not available from this repository ...
Men who had high levels of selenium, multi-vitamins, vitamin E and soy isoflavones had lower risk for prostate cancer than men with low levels of these nutrients in two new studies. Soy isoflavones slowed the growth of prostate-cancer cells in a third new study. In the selenium study, researchers measured the blood fluid (serum) levels of selenium in 724 men with prostate cancer and in 879 healthy men of the same age who entered the study at the same time, and followed up for eight years. Scientists found that men who had higher selenium levels who also reported taking multi-vitamins had 39% lower risk for prostate cancer than men with the lowest selenium levels. Doctors also found that men with higher selenium levels who reported taking more than 28 IU of vitamin E per day had 42% lower risk for prostate cancer than men with the lowest selenium levels. Men with higher selenium levels who did not take vitamin E or multi-vitamins did not have significantly lower prostate cancer risk than those ...
Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) derived Dietary Reference Values (DRVs) for selenium. The levelling off of plasma selenoprotein P (SEPP1) concentration was considered indicative of an adequate supply of selenium to all tissues and to reflect saturation of the functional selenium body pool, ensuring that selenium requirement is met. This criterion was used for establishing DRVs for selenium in adults. Evidence from human studies on the relationship between selenium intake and plasma SEPP1 concentration was reviewed. Given the uncertainties in available data on this relationship, they were considered insufficient to derive an Average Requirement. An Adequate Intake (AI) of 70 µg/day for adults was set. A review of observational studies and randomised controlled trials that investigated the relationship between selenium and health outcomes did not provide evidence for additional benefits associated with selenium intake ...
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Ever since its discovery, selenium has attracted the attention of many scientists due to its specific characteristics and behavior, which provided a wide range of applications for this element, from photo- and electrical industry to biology and medicine. The diverse applications are directly related with selenium chemical form, size and shape of its particles. When it comes to biomedical applications, it is well known fact that selenium is an essential micronutrient for animals and humans but with a narrow margin between beneficial and toxic effects. As a potential anticancer agent, its use requires consumption over the long term, so the toxicity of Se is always a crucial concern. Elemental selenium nanoparticles (Nano-Se) have emerged as a novel selenium source with the advantage of reduced risk of selenium toxicity, but with same bioavailability and efficacy in increasing the activities of selenoenzimes compared with other seleno-compounds. We synthesized stabile, amorphous, red... spherical ...
Dr Tamlin Conner Otagos Department of Psychology co-author and study lead Dr Tamlin Conner says the research reinforces links between both low and high selenium status and adverse health effects in humans - including on mood, which is her main area of expertise. A total of 978 young adults aged 17 to 25 were asked to complete a depression questionnaire and track their mood daily over the Internet for two weeks. Blood tests were also taken to determine their selenium levels. The results of this research, a collaboration between the Universitys Psychology and Human Nutrition departments, and published in the prestigious Journal of Nutrition today, suggests that there is a relationship between selenium concentration and depressive symptoms and negative mood among young adults. Young adults with either too low, or too high, levels of selenium showed the highest risk of depressive symptoms and poorer mood. However, lower concentrations of selenium were found to be even more detrimental to these ...
In three separate trial series (TS) the effect of diet composition on selenium (Se) status of dairy cows were investigated. Diets were formulated based mainly on grass (TS1), grass silage (TS2) or maize silage (TS3) with different levels of Se supplementation. Each TS comprised a total of 30 dairy cows and contained one treatment group without Se supplementation (control) and two groups with increasing levels of Se supplementation (levels 1 and 2). Selenium was administered as Na-selenite. The control groups of the different TS showed a very low Se supply of 38-54 μg Se/kg DM. At level 1 the Se supply was increased to 102-165 μg Se/kg DM and at level 2 was 294-373 μg Se/kg DM. After completion of the 6-week trials the average plasma Se concentration of the control cows (without Se supplementation) across all TS was 21.5 μg/l; this increased significantly following Se supplementation, to 37.7 μg/l at level 1 and 61.5 μg/l at level 2. The plasma glutathione peroxidase (GSH-Px) activity of ...
In three separate trial series (TS) the effect of diet composition on selenium (Se) status of dairy cows were investigated. Diets were formulated based mainly on grass (TS1), grass silage (TS2) or maize silage (TS3) with different levels of Se supplementation. Each TS comprised a total of 30 dairy cows and contained one treatment group without Se supplementation (control) and two groups with increasing levels of Se supplementation (levels 1 and 2). Selenium was administered as Na-selenite. The control groups of the different TS showed a very low Se supply of 38-54 μg Se/kg DM. At level 1 the Se supply was increased to 102-165 μg Se/kg DM and at level 2 was 294-373 μg Se/kg DM. After completion of the 6-week trials the average plasma Se concentration of the control cows (without Se supplementation) across all TS was 21.5 μg/l; this increased significantly following Se supplementation, to 37.7 μg/l at level 1 and 61.5 μg/l at level 2. The plasma glutathione peroxidase (GSH-Px) activity of ...
i have high selenium without taking a selenium separate supplement and only a multi vitamin and fishoil , flaxseed oil, saw palmetto and evening primrose oil and viviscal pro with oyster powder and...
The selenium (Se) content in human hair is useful as an indicator of human Se intake and status. In this regard, when measuring the hair Se concentrations in Chinese inhabitants across northeast to southeast China, the results indicated that generally 84% of all residents have normal hair Se content. Between the sexes, the average hair Se content of males was higher than that of females, irrespective of districts. When comparing geographical regions, the average hair Se content of southern residents was greater than that of northern residents, regardless of gender. Historically, the overall hair Se content of todays inhabitants decreased between 24% and 46% when compared with the inhabitants living in the same geographic region 20 years ago. The decrease of hair Se content may be related to the overall decrease of grain consumption and the lower Se content in the staple food rice.
2508 Numerous selenium-containing compounds are being investigated as cancer chemopreventive agents in both laboratory studies and clinical investigations. In many of these studies, drug- or nutrient-induced increases in blood selenium levels are associated with tumor inhibition. Previous small scale clinical studies have indicated that selenium-containing agents are also effective at increasing glutathione levels in blood and tissues, resulting in decreased levels of oxidative stress. Our objectives were to examine the relationship between blood selenium levels and glutathione status in healthy free-living individuals and in subjects administered selenium-enriched yeast as a dietary supplement. In the first study, 336 healthy adults between 18-50 yr of age (161 Blacks, 175 Whites; 168 females, 168 males) were recruited as part of a community-based study of smoking biomarkers and health. Blood selenium levels, measured by inductively coupled plasma mass spectroscopy, were 9% greater in Whiles ...
article{54d39bb4-e7b5-47ae-988a-5e66994332e3, abstract = {Glutathione peroxidase (GSHPx) activity, and total and soluble selenium content were compared in five bovine and porcine organs. The highest GSHPx activity in porcine tissues was found in the liver (35.0 U/g), spleen (29.3 U/g) and kidney (27.3 U/g) with much lower values in the heart (1.8 U/g) and diaphragm (0.8 U/g). A different pattern with lower inter-organ variation in GSHPx activity was observed in cattle: kidney (8.5 U/g), spleen (8.0 U/g), heart (5.8 U/g), liver (4.0 U/g) and diaphragm (2.1 U/g). The total selenium content was similar in both species with the highest content in the kidney (1764 and 1665 ng/g; pig/bovine), followed by liver (533 and 307 ng/g), spleen (370 and 284 ng/g), heart (201 and 205 ng/g) and diaphragm (144 and 116 ng/g). The percentage of soluble selenium varied more among the pig organs (46-94%) than among bovine organs (61-75%). The results show a marked variation in the activity of the selenium-containing ...
Dr Wallach Dead Doctors Dont Lie SELENIUM MAY HELP PREVENT CERTAIN TYPES OF CANCER Apparent beneficial effects also for reducing cancer mortality SELENIUM 888 441 4184
Selenium is generally known as an antioxidant due to its presence in selenoproteins as selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly concentration and chemical species dependent. One class of selenium compounds is a potent inhibitor of cell growth with remarkable tumor specificity. These redox active compounds are pro-oxidative and highly cytotoxic to tumor cells and are promising candidates to be used in chemotherapy against cancer. Herein we elaborate upon the major forms of dietary selenium compounds, their metabolic pathways, and their antioxidant and pro-oxidant potentials with emphasis on cytotoxic mechanisms. Relative cytotoxicity of inorganic selenite and organic selenocystine compounds to different cancer cells are presented as evidence to our perspective. Furthermore, new novel classes of selenium compounds specifically designed to target tumor cells are presented and the potential of selenium in modern oncology is extensively discussed.
1]If you are at all like me, a selenium deficiency was not something on the radar in terms of my infertility struggles. However, a study just published in Australia has found that selenium levels may be another piece to the infertility puzzle. Selenium is a natural antioxidant that is found in protein rich foods; such as seafood, nuts and red meat. It is mostly known for helping balance the bodys immune system, thyroid production and works to detoxify the body from harmful chemicals. There have been studies that have linked selenium imbalances to male infertility, but researchers had not yet looked at the effect it has on women.. It turns out that when women are healthy and fertile; their ovarian follicles contain selenium levels that are twice as high as in those that were not optimal for pregnancy. The tricky part here though is that when women have levels of selenium that are too high, it is toxic for the body. So there is definitely a careful balance between having too much and not enough ...
The independent and joint associations of serum selenium and vitamin A (retinol) and E (alpha tocopherol) concentrations with the risk of death from cancer were studied in 51 case-control pairs--that is, 51 patients with cancer, each paired with a control matched for age, sex, and smoking. Case-control pairs came from a random sample of some 12000 people aged 30-64 years resident in two provinces of eastern Finland who were followed up for four years. Patients who died of cancer during the follow up period had a 12% lower mean serum selenium concentration (p = 0.015) than the controls. The difference persisted when deaths from cancer in the first follow up year were excluded. The adjusted risk of fatal cancer was 5.8-fold (95% confidence interval 1.2-29.0) among subjects in the lowest tertile of selenium concentrations compared with those with higher values. Subjects with both low selenium and low alpha tocopherol concentrations in serum had an 11.4-fold adjusted risk. Among smoking men with ...
Algotar AM, Stratton MS, Ahmann FR, et al. Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer. Prostate. 2013;73(3):328-35.. Beck MA, Nelson HK, Shi Q, Van Dael P, Schiffrin EJ, Blum S, Barclay D, Levander OA. Selenium deficiency increases the pathology of an influenza virus infection. FASEB J. 2001;15(8):1481-3.. Bleys J, Navas-Acien A, Guallar E. Selenium and diabetes: more bad news for supplements.Ann Intern Med. 2007 Aug 21;147(4):271-2.. Bleys J, Navas-Acien A, Guallar E. Serum selenium levels and all-cause, cancer, and cardiovascular mortality among US adults. Arch Intern Med. 2008;168(4):404-10.. Bjelakovic G, Nikolova D, Simonetti RG, Gluud C. Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis. Lancet. 2004;364:1219-28.. Brawley OW, Panes H. Prostate cancer prevention trials in the USA. Eur J Cancer. 2000;36(10):1312-5.. Cai J, Nelson KC, Wu M, Sternberg P Jr, Jones DP. ...
Two of the seleno-dependent enzymes Glutathione Peroxidase (GPX) and Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPX) are speculated to play a key-role in the defence of neuronal cells against oxygen radical formation and peroxidative processes. Researchers findings support the hypothesis that the presence of selenium depletion in the brain amongst patients with epilepsy constitutes an important triggering factor for the origin of intractable seizures and subsequent neuronal damage ...
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Save 41% Lindberg - Selenium 200 mcg Yeast Free 120 Capsules Selenium 200 mcg Yeast Free Provides Antioxidant Support* Selenium is a trace mineral that is essential to health. It has antioxidant properties that help prevent cellular damage from free radicals.* Selenium may reduce the risk of certain cancers. Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer. However, FDA has determined that this evidence is limited and not conclusive. Vegetarian Capsules.
The purpose of this study is to investigate the relationship of serum selenium levels and the risk of developing prostate cancer. It has been documented that antioxidants reduce the incidence of cancer by eradicating free radicals that damage DNA, thus increasing the risk of cancer. Selenium is a component of the antioxidant enzyme glutathione peroxidase, whose role in cancer prevention has been controversial in the last 40 years. Methodology: A systematic review of evidence-based literature was performed utilizing the following search engines: MEDLINE FirstSearch, ArticleFirst, dissertations, and Papers First and a bibliographic search of selected articles. MeSH ( medical subject heading terms) and text words utilized in this study include: serum, selenium, prostate, neoplasia, risk, nutrition, adenocarcinoma, male, prostatic intraepithelial neoplasm, and prostatic neoplasia. Results: The results of the evidence-based literature results are consistent with the epidemiologic studies available ...
Background: Autoimmune mechanisms are involved in the etiology of Alopecia areata. It is also shown that Selenium has some effects on regulation of autoimmune mechanisms. Objective: To compare the plasma level of Selenium between those with and without Alopecia areata. Patients and Methods: In this case-control study, 29 patients with Alopecia areata referred to Razi hospital in Tehran, and 29 persons without this disease were selected consequently. Plasma level of Selenium was determined and compared between the groups. Results: The mean age of cases was 24.9±10.5 and of controls was 29.1±10.5 years. In both groups 15 (51.7%) patients were male and 14 (48.3%) of them were female. The mean plasma Selenium level in cases was significantly lower than what was observed in controls (62.1±13.3 g/l vs. 88.3±13.2 g/l, P|0.0005). Conclusion: This study indicated that mean plasma Selenium level in patients with Alopecia areata was lower than those without this disorder. It is recommended to evaluate the
Although it is toxic in large doses, selenium is an essential micronutrient for animals. In plants, it sometimes occurs in amounts toxic as forage, e.g. locoweed. Selenium is a component of the amino acids selenocysteine and selenomethionine. In humans, selenium is a trace element nutrient that functions as cofactor for glutathione peroxidases and certain forms of thioredoxin reductase. Selenium-containing proteins are produced from inorganic selenium via the intermediacy of selenophosphate (PSeO33−). Selenium is an essential micronutrient in mammals, but is also recognized as toxic in excess. Selenium exerts its biological functions through selenoproteins, which contain the amino acid selenocysteine. Twenty-five selenoproteins are encoded in the human genome. The glutathione peroxidase family of enzymes (abbreviated GSH-Px) catalyze reduction of hydrogen peroxide and organic hydroperoxides: 2H + H2O2 → GSSG + 2 H2O The two H atoms are donated by thiols in a process that begins with ...
Efficacy of antioxidant vitamins (vitamin C, vitamin E, beta-carotene) and selenium supplement on D-galactosamine-induced lung injury in rats ...
TY - JOUR. T1 - Selenium in the blood of patients with colorectal cancer and neoplastic polyp.. AU - Rumi, G.. AU - Imre, I.. AU - Sülle, C.. AU - Sarudi, I.. AU - Kelemen, J.. AU - Lassú, Z.. PY - 1992. Y1 - 1992. N2 - Samples of whole blood were obtained from 51 patients with newly diagnosed colorectal cancer as well as from 76 patients with neoplastic colorectal polyp, and from 30 healthy blood bank donors. Selenium was determined by the fluorimetric method. Significantly decreased selenium concentrations of blood samples from patients with colorectal cancer and villous adenoma were found. There was not any correlation between the blood selenium levels of patients with adenomatous polyp and the severity of dysplasia in removed polyps. The lowest mean selenium level in patients with villous adenoma indicates that selenium deficiency may be an important factor in the development of colorectal cancer arising from villous adenomas.. AB - Samples of whole blood were obtained from 51 patients ...
Selenium deficiency is relatively rare in healthy well-nourished individuals.[citation needed] Few cases in humans have been reported.[citation needed] Selenium deficiency in combination with Coxsackievirus infection can lead to Keshan disease, which is potentially fatal. Selenium deficiency also contributes (along with iodine deficiency) to Kashin-Beck disease. The primary symptom of Keshan disease is myocardial necrosis, leading to weakening of the heart. Kashin-Beck disease results in atrophy, degeneration and necrosis of cartilage tissue. Keshan disease also makes the body more susceptible to illness caused by other nutritional, biochemical, or infectious diseases. Selenium is also necessary for the conversion of the thyroid hormone thyroxine (T4) into its more active counterpart, triiodothyronine, and as such a deficiency can cause symptoms of hypothyroidism, including extreme fatigue, mental slowing, goiter, cretinism, and recurrent miscarriage. It can occur in patients with severely ...
General: Selenium is a metallic substance that is available in a variety of chemical compounds. Often selenium is attached to an organic molecule as in selenocysteine, selenomethionine, and kappa-selenocarrageenan. In broccoli, garlic, onions, and other selenium-accumulating plants it is found as Se-methylselenocysteine or selenocystathionine. In dietary supplements selenium is commonly provided as selenomethionine or in a selenite or selenate salt form. Often selenium is given as selenized yeast, which is common brewers yeast that has been grown in selenium-rich media. After ingestion as a selenate salt, selenite salt, or as one of the organic forms, selenium must be reduced or metabolized to form hydrogen selenide, an important intermediary form. Selenide is essential for the activity of selenoproteins, such as the glutathione peroxidase enzyme (GSH-Px). The primary organic forms of selenium are the amino acid-based selenocysteine and selenomethionine. Selenomethionine is incorporated ...
Di(ethylhexyl)phthalate (DEHP), the most widely used plasticizer, was investigated to determine whether an oxidative stress process was one of the underlying mechanisms for its testicular toxicity potential. To evaluate the effects of selenium (Se), status on the toxicity of DEHP was further objective of this study, as Se is known to play a critical role in testis and in the modulation of intracellular redox equilibrium. Se deficiency was produced in 3-weeks-old Sprague-Dawley rats feeding them ≤0.05 mg Se /kg diet for 5 weeks, and Se-supplementation group was on 1 mg Se/kg diet. DEHP-treated groups received 1000 mg/kg dose by gavage during the last 10 days of the feeding period. Activities of antioxidant selenoenzymes [glutathione peroxidase 1 (GPx1), glutathione peroxidase 4 (GPx4), thioredoxin reductase (TrxR)], catalase (CAT), superoxide dismutase (SOD), and glutathione S-transferase (GST); concentrations of reduced glutathione (GSH), oxidized glutathione (GSSG), and thus the GSH/GSSG redox ratio;
Selenium Yeast is an Effective in Vitro and in Vivo Antioxidant and Hypolipemic Agent in Normal Hamsters Abstract: Selenium as the selenite, selenomethionine, ebselen and yeast was investigated in an in vitro low density lipoprotein oxidation model to mimic the first step in atherogenesis. Ebselen and selenium yeast were found to be the best antioxidents of the forms of selenium. Selenium yeast was then given in two doses as a supplement to chow-fed hamsters for 15 days. The yeast significantly decreased total plasma cholesterol and the atherogenic index but did not significantly diminish HDL and triglycerides. Selenium yeast significantly decreased plasma lipid peroxides, low density lipoprotein oxidation lag time, and maximum slope of oxidation. These results indicate that selenium yeast is a powerful in vitro and in vivo antioxidant as well as a hypolipemic agent. These two actions could explain the benefit of selenium seen in epidemiology studies. Additional note by poster: The selenium ...
Together with the related barium and zinc selenites, sodium selenite is mainly used in the manufacture of colorless glass. The pink color imparted by these selenites cancels out the green color imparted by iron impurities.[3] Because selenium is an essential element, sodium selenite is an ingredient in dietary supplements such as multi-vitamin/mineral products, but supplements that provide only selenium use L-selenomethionine or a selenium-enriched yeast. The US Food and Drug Administration approved a selenium supplement to animal diets; the most common form is sodium selenite for pet foods. According to one article, not much was known about which selenium compounds to approve for use in animal feeds when the decisions were made back in the 1970s .. At the time the regulatory action was taken, only the inorganic selenium salts (sodium selenite and sodium selenate) were available at a cost permitting their use in animal feed. [4] ...
Selenoprotein P (SePP), the major selenoprotein in plasma, has been implicated in selenium transport, selenium detoxification or antioxidant defence. We generated SePP-knockout mice that were viable, but exhibited reduced growth and developed ataxia. Selenium content was elevated in liver, but low in plasma and other tissues, and selenoenzyme activities changed accordingly. Our data reveal that SePP plays a pivotal role in delivering hepatic selenium to target tissues.
TY - JOUR. T1 - The effects of selenium and copper deficiencies on glutathione S-transferase and glutathione peroxidase in rat liver. AU - Arthur, J R. AU - Morrice, P C. AU - Nicol, F. AU - Beddows, S E. AU - Boyd, R. AU - Hayes, J D. AU - Beckett, G J. PY - 1987/12/1. Y1 - 1987/12/1. N2 - Selenium (Se) deficiency in rats produced significant increases in the activity of hepatic glutathione S-transferase (GST) with 1-chloro-2,4-dinitrobenzene as substrate and in various GST isoenzymes when determined by radioimmunoassay. These changes is GST activity and concentration were associated with Se deficiency that was severe enough to provoke decreases of over 98% in hepatic Se-containing glutathione peroxidase activity (Se-GSHpx). However, decreases in hepatic Se-GSHpx of 60% induced by copper (Cu) deficiency had no effect on GST activity or concentration. Increased GST activity in Se deficiency has previously been postulated to be a compensatory response to loss of Se-GSHpx, since some GSTs have a ...
BACKGROUND: Although an increasing role of genetic susceptibility has been recognized, the role of environmental risk factors in amyotrophic lateral sclerosis (ALS) etiology is largely uncertain; among neurotoxic chemicals, epidemiological and biological plausibility has been provided for pesticides, the heavy metal lead, the metalloid selenium, and other persistent organic pollutants. Selenium involvement in ALS has been suggested on the basis of epidemiological studies, in vitro investigations, and veterinary studies in which selenium induced a selective toxicity against motor neurons. OBJECTIVE: Hypothesizing a multistep pathogenic mechanism (genetic susceptibility and environmental exposure), we aimed to study selenium species in ALS patients carrying disease-associated gene mutations as compared to a series of hospital controls. METHODS: Using advanced analytical techniques, we determined selenium species in cerebrospinal fluid sampled at diagnosis in 9 ALS patients carrying different gene ...
Selenium is a chemical element with symbol Se and atomic number 34. It is a nonmetal with properties that are intermediate between those of its periodic table column-adjacent chalcogen elements sulfur and tellurium. It rarely occurs in its elemental state in nature, or as pure ore compounds. Selenium (Greek σελήνη selene meaning Moon) was discovered in 1817 by Jöns Jakob Berzelius, who noted the similarity of the new element to the previously-known tellurium (named for the Earth).. Selenium is found impurely in metal sulfide ores, where it partially replaces the sulfur. Commercially, selenium is produced as a byproduct in the refining of these ores, most often during copper production. Minerals that are pure selenide or selenate compounds are known, but are rare. The chief commercial uses for selenium today are in glassmaking and in pigments. Selenium is a semiconductor and is used in photocells. Uses in electronics, once important, have been mostly supplanted by silicon semiconductor ...
Abstract: Aim: Using structural bioinformatics methods, the aim is to assess the hypothesis that hepatitis C virus (HCV) encodes a glutathione peroxidase (GPx) gene in an overlapping reading frame, linking HCV expression and pathogenesis to the Se status and dietary oxidant/antioxidant balance of the host. Methods: The putative HCV GPx gene was identified by searching viral sequence databases, using conserved GPx active site sequences as probes, giving particular weight to the UGA (selenocysteine) codon. Multiple sequence alignments were generated and analyzed to validate the sequence similarity, and to establish the degree of conservation of the identified genomic features in HCV. Molecular modeling was used to assess the structural feasibility of the proposed homology. Results: The GPx homology region overlaps the NS4 gene, and is well conserved in HCV. The sequence similarity of the conserved active site regions to a set of known GPx is high (4 to 6 SD greater than expected for similar random ...
Manitoba is generally accepted to be in a low to deficient selenium state. In spite of its importance, selenium analysis is not routinely done on forages due to the high cost ($58/sample). Because of this, the status of selenium in forages is not well documented. In the fall of 2001, Lori-Lynn Benn (livestock specialist in Teulon) and I decided to survey forage samples from each of the 6 ag. rep districts in the Interlake for selenium content. Due to the high cost, the number of samples per ag. rep. district was limited. The results are outlined below ...
BACKGROUND: Cardiac Troponin I (cTnI) is known as a cardiac biomarker in determining the myocardial damage of diseases which affect the heart muscle. OBJECTIVES: This study aims to evaluate the serum cTnI concentration in Markhoz Breed goats suffering selenium (Se) deficiency and its correlation with electrocardiographic parameters, and activity of creatine kinase (CK) and aspartate aminotransferase (AST) enzymes, as well as to determine the diagnostic value of troponin in that disease. METHODS: Blood samples of 94 goat kids of Markhoz breed with the age less than one month were taken, serum analyzed for the assessment of cTnI, CK and AST, 2 ml blood was used for determination of selenium concentration. Electrocardiography was recorded from all kids by using base-apex lead. Kids were divided into two groups based on serum selenium concentration. RESULTS: The concentration of cTnI was significantly higher in deficient kids compared with the control group. Results indicated significant negative
Looking for online definition of selenium converter plants in the Medical Dictionary? selenium converter plants explanation free. What is selenium converter plants? Meaning of selenium converter plants medical term. What does selenium converter plants mean?
Selenium (Se) is an element recognized as an essential micronutrient in eukaryote organisms. Selenoproteins contain selenium as selenocysteine, the 21st amino acid. Selenium plays a role in cell growth and functioning. At low concentrations, it can induce growth and at high concentrations, it can cause a cell to stop growing and potentially have toxic effects on the cell and organism. When selenium levels are high, oxidative stress results by the production of reactive oxidative species. Selenoproteins, however, can aid the antioxidant response in the cell. Ticks are arthropods of interest, as they are one of few that contain many selenogenes, possibly the reason for their robust antioxidant system. Ticks are obligate hematophagous ectoparasite and require this strong and organized antioxidant system for when oxidative stress is induced during blood feeding and digestion. In this study, the effects of sublethal sodium selenite concentration on the female Amblyomma maculatum ticks antioxidant system
Inhibitory activity of selenium nanoparticles functionalized with oseltamivir on H1N1 influenza virus Yinghua Li,1 Zhengfang Lin,1 Min Guo,1 Yu Xia,1 Mingqi Zhao,1 Changbing Wang,1 Tiantian Xu,1 Tianfeng Chen,2 Bing Zhu1 1Virus Laboratory, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, 2Department of Chemistry, Jinan University, Guangzhou, People’s Republic of China Abstract: As an effective antiviral agent, the clinical application of oseltamivir (OTV) is limited by the appearance of drug-resistant viruses. Due to their low toxicity and excellent activity, the antiviral capabilities of selenium nanoparticles (SeNPs) has attracted increasing attention in recent years. To overcome the limitation of drug resistance, the use of modified NPs with biologics to explore novel anti-influenza drugs is developing rapidly. In this study, OTV surface-modified SeNPs with superior antiviral properties and restriction on drug resistance
BACKGROUND: Evidence of the chemopreventive effects of the dietary antioxidants alpha-tocopherol (vitamin E) and l-selenomethionine (selenium) comes from secondary analysis of two phase III clinical trials that found treatment with these antioxidants reduced the incidence of prostate cancer. To determine the effects of selenium and vitamin E in blood and prostate tissue, we undertook a preoperative feasibility study complementary to the currently ongoing Selenium and Vitamin E Cancer Prevention Trial. METHODS: Forty-eight patients with clinically localized prostate cancer enrolled on this 2 x 2 factorial design study were randomized to take selenium, vitamin E, both, or placebo for 3 to 6 weeks before prostatectomy. Sera were collected from patients before and after dietary supplementation. Thirty-nine patients were evaluable, and 29 age-matched disease-free men served as controls. Mass profiling of lipophilic serum proteins of lower molecular weight (2-13.5 kDa) was conducted, and mass spectra data
Selenomethionine, by Neurobiologix, has antioxidant properties that help the body prevent cellular damage. One of its most valuable roles is as a cofactor of an important antioxidant enzyme in the body called glutathione peroxidase.
L-Selenomethionine is selenium chelated to the amino acid L-methionine. L-Selenomethionine is the form of selenium most frequently found in nature.
BACKGROUND AND PURPOSE: Plasma glutathione peroxidase (GPx-3)-deficiency increases extracellular oxidant stress, decreases bioavailable nitric oxide, and promotes platelet activation. The aim of this study is to identify polymorphisms in the GPx-3 gene, examine their relationship to arterial ischemic stroke (AIS) in a large series of children and young adults, and determine their functional molecular consequences. METHODS: We studied the GPx-3 gene promoter from 123 young adults with idiopathic AIS and 123 age- and gender-matched controls by single-stranded conformational polymorphism and sequencing analysis. A second, independent population with childhood stroke was used for a replication study. We identified 8 novel, strongly linked polymorphisms in the GPx-3 gene promoter that formed 2 main haplotypes (H1 and H2). The transcriptional activity of the 2 most prevalent haplotypes was studied with luciferase reporter gene constructs. RESULTS: The H2 haplotype was over-represented in both patient ...
1985) Selenium status and glutathione peroxidase activity in iron deficient and normal rabbits. Nutrition Reports International, 31 . pp. 351-359. ...
Kruze, J., Ceballos, A., Stryhn, H., Mella, A., Matamoros, R., Contreras, P. A., … Wittwer, F. (2007). Somatic cell count in milk of selenium-supplemented dairy cows after an intramammary challenge with Staphylococcus aureus. Journal Of Veterinary Medicine Series A, 54(9), 478-483. doi:10.1111/j.1439-0442.2007.00999. ...
PubMed journal article Expression of plasma glutathione peroxidase in human liver in addition to kidney, heart, lung, and breast in humans and rodent were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
457 pp. p 23/457: People may be exposed to higher-than-normal levels of selenium at hazardous waste sites by swallowing soil or water, or by breathing dust. In some parts of the United States, especially in the western states, some soils naturally have higher levels of selenium compounds. Some plants can build up selenium to levels that harm livestock feeding on them. In these areas, people could be exposed to too much selenium if they eat a lot of locally grown grains and vegetables or animal products that have built up high levels of selenium. People may also be exposed to selenium from industrial sources.. P. 24/457: Hazardous waste sites at which selenium is present could represent a major source of exposure. The way that selenium can enter the body from a particular site depends on such factors as whether vegetables are grown in soil in which selenium from the site has been deposited, whether water at the site contains selenium and is able to flow into drinking water supplies, and ...
NowSelenium200 mcgYeast-Free90 CapsSUGGESTED USAGE: As a dietary supplement, take one capsule daily, preferably with meals. Do not exceed one capsule daily except under the guidance of a health care practitioner. Persons living in areas of high soil selenium, such as the Dakotas, should consult a physician prior to use.Selenium is an essential trace mineral and functions as part of the antioxidant enzyme glutathione peroxidase. It is bonded to the essential sulfur amino acid, methionline, in a naturally occurring form as found in the diet. Selenium is found mostly abundantly in Brazil Nuts, organ meats, seafood, and wheat germ.** This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Supplement FactsServing Size 1 CapsuleAmount Per Serving% Daily ValueSelenium (as L-Selenomethionine)200 mcg 286% Other Ingredients: Rice Flour, Magnesium StearateContains no yeast, sugar, salt, milk, corn, wheat, gluten, soy, preservatives or colors.
The trace element selenium is an essential micronutrient that is required for the biosynthesis of selenocysteine-containing selenoproteins. Most of the known selenoproteins are expressed in the thyroid gland, including some with still unknown functions. Among the well-characterized selenoproteins ar …
Title: Zinc, Metallothioneins and Longevity: Interrelationships with Niacin and Selenium. VOLUME: 14 ISSUE: 26. Author(s):E. Mocchegiani, M. Malavolta, E. Muti, L. Costarelli, C. Cipriano, F. Piacenza, S. Tesei, R. Giacconi and F. Lattanzio. Affiliation:Immunology Ctr. (Laboratory of Nutrigenomic and Immunosenescence), Res. Dept. INRCA, Via Birarelli, 8, 60121, Ancona, Italy.. Keywords:Zinc, Niacin, Selenium, Metallothionein, Immune Response, Antioxidant Defense, Ageing, Longevity. Abstract: Ageing is an inevitable biological process with gradual and spontaneous biochemical and physiological changes and increased susceptibility to diseases. Some nutritional factors (zinc, niacin, selenium) may remodel these changes leading to a possible escaping of diseases, with the consequence of healthy ageing, because they are involved in improving immune functions, metabolic homeostasis and antioxidant defence. Experiments performed in vitro (human lymphocytes exposed to endotoxins) and in vivo (old ...
TY - JOUR. T1 - DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals. T2 - a short-term supplementation trial with respect to GPX1 and SEPP1 polymorphism. AU - Jablonska, E.. AU - Raimondi, S.. AU - Gromadzinska, J.. AU - Reszka, E.. AU - Wieczorek, E.. AU - Krol, M. B.. AU - Smok-Pieniazek, A.. AU - Nocun, M.. AU - Stepnik, M.. AU - Socha, K.. AU - Borawska, M. H.. AU - Wasowicz, W.. PY - 2015/12/10. Y1 - 2015/12/10. N2 - Abstract: Purpose: Selenium, both essential and toxic element, is considered to protect against cancer, though human supplementation trials have generated many inconsistent data. Genetic background may partially explain a great variability of the studies related to selenium and human health. The aim of this study was to assess whether functional polymorphisms within two selenoprotein-encoding genes modify the response to selenium at the level of oxidative stress, DNA damage, and mRNA expression, especially in the individuals with a ...
The case of a 64 year old female patient is presented who has treated herself for 9 months with various Indian Ayurvedic herbal products for her vitiligo and.. Selenium Supplement - For Reproductive Support - 60 Tablets. Selenium Supplement - For Reproductive Support. and the neutralization of alcohol,.Auto-evaluation Quiz. Show all questions ,= =, What are two kinds of stimulants? ? alcohol and nicotine ?. because is often sold in powder and tablets are better ?.Some bingo houses ban alcohol inside,. These tablets are available in blister packs containing 2,. [url=]cheap rulide[/url].The hashtag we will be using for the conversation on Twitter for this workshop is #stemk12dialogue. alcohol, other meals, and. tablets, cameras, smartphones.Carrusel: Apple cider vinegar. the alcohol is converted into vinegar by acetic acid-forming bacteria. Apple cider vinegar tablets can also be taken,.El tipo de facial o limpieza facial dependerá. uk/services ,provera tablets ...
In Finland, the use of white clover has recently increased especially in organic farming. However, information on its mineral content is very sparse. Therefore, contents of Ca, P, Mg, K and Se of white clover grass without nitrogen (CG0) and grass-only pastures with annual nitrogen rates of 0 (G0), 120 (G120) and 250 (G250) kg ha-1 were studied in organic soil. The pastures were grazed twice per season by growing lambs. Feed intake was determined by n-alkanes. The white clover contents averaged 36% and 42% in the first and the second grazing period. At the beginning of grazing the Se content averaged 0.19, 0.16, 0.29 and 0.29 ppm in CG0, G0, G120 and G250 pastures (p=0.01), respectively. When the season progressed, the Se content decreased in all pastures and averaged 0.015 ppm in late August. There was no difference in Se content between fertilized G120 and G250 pastures (0.09 ppm), but Se contents of unfertilized CG0 (0.07 ppm) and G0 pastures (0.06 ppm) were significantly ( ...
Atherosclerosis. 2010 Jun;210(2):662-7. doi: 10.1016/j.atherosclerosis.2010.01.021. Epub 2010 Jan 25. Multicenter Study; Research Support, N.I.H., Extramural
Selenium deficiency may play an important role in the initiation and progression of autoimmune thyroid disease. To compare serum selenium (s‐Se) values in patients with newly diagnosed autoimmune thyroid disease and controls from the Danish population. S‐Se was measured in triplicate by a fluorimetric method. Patients with newly diagnosed Graves disease (GD) (n = 97) or autoimmune overt hypothyroidism (AIH) (n = 96), euthyroid subjects with high serum levels of thyroid peroxidase antibody (TPO‐Ab) (TPO‐Ab , 1500 U/ml, n = 92) and random controls (n = 830). Differences in s‐Se values. S‐Se was lower in patients with GD than in controls (mean (SD), GD: 89·9 μg/l (18·4); controls: 98·8 μg/l (19·7), P , 0·01). This was confirmed in a multivariate logistic regression model adjusting for age, sex, mineral supplements, smoking, geographical region and time of sampling (P , 0·01). In a linear model, s‐Se was similar in patients with AIH (mean (SD): 98·4 μg/l (24·9)) and in ...
in Molecules (2016), 21(4), 545. This review article examines the role of selenium (Se) and the effects of Se supplementation especially in the bovine species. Selenium is an important trace element in cattle. Some of its roles include ... [more ▼]. This review article examines the role of selenium (Se) and the effects of Se supplementation especially in the bovine species. Selenium is an important trace element in cattle. Some of its roles include the participation in the antioxidant defense the cattle farms. The nutritional requirements of Se in cattle are estimated at 100 μg/kg DM (dry matter) for beef cattle and at 300 μg/kg DM for dairy cows. The rations high in fermentable carbohydrates, nitrates, sulfates, calcium or hydrogen cyanide negatively influence the organisms use of the selenium contained in the diet. The Se supplementation may reduce the incidence of metritis and ovarian cysts during the postpartum period. The increase in fertility when adding Se is attributed to the ...
Selenium may protect against the development of esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), and gastric cardia adenocarcinoma (GCA).
Get information, facts, and pictures about selenium at Make research projects and school reports about selenium easy with credible articles from our FREE, online encyclopedia and dictionary.
Selenium (Se) is an essential trace element and metalloid involved in several key metabolic activities: protection against oxidative damage, regulation of immune and thyroid function, and fertility. Several recent lines of evidence from epidemiology, genetic, and transgenic animal studies suggest that Se may play a protective role in Osteoarthritis (OA). However, the exact protective mechanism of Se is still unclear. In this study, we hypothesized that Se exerts its chondroprotective benefit via an anti-oxidative and anti-inflammatory effect mediated by specific selenoproteins that neutralize cytokine-induced inflammatory responses in chondrocytes. We established an in vitro system for studying the effect of Se in the chondrosarcoma cell line SW-1353 and in human primary chondrocytes. Selenomethionine (SeMet) induced gene expression and enzyme activity of both antioxidative enzymes glutathione peroxidase (GPX) and thioredoxin reductase (TR) in SW-1353 cells. Our data suggest that Se may be ...
Addolorato G, Gasparinin A, Marcoccia S, et al. Prenatal exposure to ethanol in rats: effects on liver energy level and antioxidant status in mothers, fetuses, and newborns. Alcohol 14: 569-573, 1997 Medline. Afifi NM, Abdel-Rahman MS, Nassar AM. Effect of alcohol and/or cocaine on blood glutathione and the ultra-structure of the liver of pregnant CF-1 mice. Toxicol. Lett. 98: 1-12, 1998 Medline. Aydin A, Sayal A, Isimir A. Plasma glutathione peroxidase activity and selenium levels of newborns and jaundice. Biol. Trace Elem. Res. 58: 85-90, 1997 Medline. Bohles H. Antioxidative vitamins in prematurely and maturely born infants. Int. J. Vitamin Nutr. Res. 67: 321-328, 1997 Medline. Bounous G, Kongshavn PAL, Taveroff A, Gold P. Evolutionary traits in human milk proteins. Medical Hypothesis 27: 133-140, 1988 Medline. Branch DW, Mitchell MD, Miller E, et al. Pre-eclampsia and serum antibodies to oxidized low-density lipoprotein. Lancet 343: 645-646, 1994 Medline. Brown LA, Perez JA, Harris FL, Clark ...
Background: Studies have shown that zinc and selenium deficiency is common in nonalcoholic fatty liver disease (NAFLD). However, the effects of zinc and selenium co-supplementation before and/or after disease progression on NAFLD are not clear enough. The aim of this study was to compare the effects of zinc and selenium co-supplementation before and/or after disease progression on NAFLD prognosis.Methods: Forty male Sprague-Dawley rats (197±4 g) were randomly assigned to 4 dietary groups: normal-fat diet (NFD; receiving 9% of calories as fat), high-fat diet (HFD; receiving 82% of calories as fat), supplementation before disease progression (S+HFD), and supplementation after disease progression (HFD+S). The diets were implemented over a 20-week period in all the groups. Biochemical and histologic parameters were compared between the 4 groups, and between-group comparisons were also carried out.Results: There were significant differences in the average food dietary intake (P
Selenium Nanoparticles Synthesized Using Pseudomonas stutzeri (MH191156) Show Antiproliferative and Anti-angiogenic Activity Against Cervical Cancer Cells
This enzyme is a critical component of the bodys natural detoxification mechanisms. SUGGESTED USAGE: As a dietary supplement, take one Vcap® daily, preferably with meals. Dosages as high as 400 mcg/day (2 capsules daily) may be recommended by a healthcare practitioner. BENEFITS: Selenium is an essential trace mineral and functions as part of the antioxidant enzyme glutathione perioxidase and complements the actions of vitamin E. It is bonded to the essential sulfur amino acid, methionine, in a naturally occurring form as found in the diet. Selenium is found most abundantly in Brazil nuts, organ meats, seafood, and wheat germ.* Supplement Facts Serving Size: Amount Per Serving % Daily Value Serving Size 1 Vcap® Servings Per Container
A group of researchers has discovered the molecular mechanism behind the human metabolism of selenium a trace element that is key to health and wellbeing. It is believed selenium protects people from conditions such as mood swings, cardiovascular disease, viral infections and cancer, and selenocysteine is the most bioactive metabolite of selenium. The team, which included scientist from Yale University and University of Illinois at Chicago, has described how selenocysteine is created on a super-sized tRNA molecule. The other 20 amino acids and their associated tRNAs use the same protein vehicle for transport to the ribosome, but selenocystine appears to have its own large tRNA that does so. Selenocysteine has been found to be a critical component of enzymes involved in a number of normal and disease processes, says Michael Bender of the National Institutes of Health s National Institute of General Medical Sciences. This study could ultimately have an impact on many aspects of human health, ...
... selenium and zinc are released into the air every year. Russia's Federal State Statistics Service lists Norilsk as the most ... selenium; and by gases (such as nitrogen and carbon oxides, sulfur dioxide, phenols and hydrogen sulfide). The Institute ...
Among the many minerals and elements he studied, he is credited with discovering cerium and selenium, and with being the first ... "Selenium". Royal Society of Chemistry. Retrieved 1 January 2020. "Silicon". Royal Society of Chemistry. Retrieved 1 January ... Berzelius discovered cerium in 1803 and selenium in 1817. Berzelius discovered how to isolate silicon in 1824, and thorium in ... Berzelius is credited with discovering the chemical elements cerium and selenium and with being the first to isolate silicon ...
... selenium; and dietary fiber. If military planners had used modest amounts of the canned vegetables and fruit available in 1915 ...
Selenium sulfide is also known to reduce dryness of scalp and folliculitis. Systemic toxicity can appear if it is applied to ... Selenium sulfide slows down epidermal proliferation. It is fungicidal to Pityrosporum ovale. It also acts as an anti- ... Like selenium sulfide, zinc pyrithione (a zinc complex with two chelating pyrithione anions) also reduces epidermal turnover ... "Selenium Sulfide". Mediline Plus. Retrieved 9 August 2012. CS1 maint: discouraged parameter (link) Sheldon, Lynne. "Uses of ...
Selenium. Food portal Maasdam cheese List of Swiss cheeses The Nibble. Cheese Glossary. See the asterisked footnote at the very ...
Selenium. National health organizations, such as the American Heart Association, Association of UK Dietitians, British National ...
Terry, N; Zayed, A. M; De Souza, M. P; Tarun, A. S (2000). "Selenium Inhigherplants". Annual Review of Plant Physiology and ... Pickleweed is used in Phytoextraction, it is highly effective at removing selenium from soil, which is absorbed by the plant ...
Selenium: In 2004, ThoughtWorks employee Jason Huggins developed Selenium, a portable software testing framework for web ... Copeland, Patrick (19 September 2007). "Selenium's Inventor". Retrieved 6 July 2016. "Selenium History". SeleniumHQ. Retrieved ...
Selenium sulfide is also used to treat tinea versicolor, a fungal infection of the skin. Deep Cleansing was launched by Chattem ... More specifically, selenium sulfide, an anti-infective agent, relieves itching and flaking of the scalp and removes the dry, ... "Selenium Sulfide". PubMed Health. National Center for Biotechnology Information, U.S. National Library of Medicine. Retrieved ... Over the counter Selsun Blue contains 1% selenium sulfide as its active ingredient in its most popular version (the word " ...
Selenious acid is a trace element indicated in people as a source of selenium. Like many selenium compounds, selenous acid is ... Symptoms of selenium poisoning can occur several hours after exposure, and may include stupor, nausea, severe hypotension and ... It is the principal oxoacid of selenium; the other being selenic acid. Selenous acid is analogous to sulfurous acid, but it is ... Selenous acid is easily formed upon the addition of selenium dioxide to water. As a crystalline solid, the compound can be seen ...
Fibre-based papers are more responsive to selenium toning. Selenium toning may not produce prints quite as stable as sepia or ... 44-47) (Book) Kodak Chemicals and Formulae (1949) Selenium, sulphide-selenium and other toners (pp. 39-41) Ilford: Toning ... selenium, sulphide, etc.)(p. 216) (Book) All about formulae for your darkroom (1942) Selenium, indirect sulphide toning, red ... Selenium toning is especially effective in this regard. Some toning processes can improve the chemical stability of the print, ...
Selenium or selenate alums are also known that contain selenium in place of sulfur in the sulfate anion, making selenate (SeO2 ... rend., 105, 114-115). "Selenium Alums". Abstracts of chemical papers. Inorganic chemistry. Journal of the Chemical Society. LII ... and/or sulfur is replaced by another chalcogen like selenium. The most common of these analogs is chrome alum KCr(SO 4) 2·12H ...
"Selenium Twins". Retrieved 8 July 2012. "Post Tower, Bonn". Bonn /: Retrieved 8 July 2012. ...
Titan=Titanium; Selen=Selenium; Argon=Argon; Orion=Aurum. The band's official abbreviation is Arcare (アルカレ, Arukare). Titan ( ...
It accumulates selenium within its tissues, and when livestock consume it, the selenium can be toxic. Astragalus bisulcatus is ... Astragalus bisulcatus accumulates large quantities of selenium when grown on soils that have selenium, the plant produces amino ... Yet, sheep and cattle have indulged in eating the plant, becoming victims of selenium toxicity. Sheep can die in thirty minutes ... Most animals avoid Astragalus bisulcatus because of the musky odor of the dimethyl selenium compounds contained in the plants ...
CS1 maint: discouraged parameter (link) Stadtman, Thressa C. (March 8, 1974). "Selenium Biochemistry". Science. American ...
... has a structure similar to that of cysteine, but with an atom of selenium taking the place of the usual sulfur. ... Selenocysteine is an analogue of the more common cysteine with selenium in place of the sulfur. Selenocysteine is present in ... When cells are grown in the absence of selenium, translation of selenoproteins terminates at the UGA codon, resulting in a ... Selenomethionine, another selenium-containing amino acid, which is randomly substituted for methionine. Merck Index, 12th ...
CS1 maint: discouraged parameter (link) "What is Selenium?". Selenium HQ. Retrieved 2014-09-02. CS1 maint: discouraged ...
"How to Set Data into Excel sheet using jxl". Selenium Easy. Selenium Easy. Retrieved 1 February 2016. jxl Java Excel API Jxl - ... JXL API is widely used with Selenium. Sample code to write to an Excel file might look like as follows: import; ... Sams, P. (2015). Selenium Essentials. Birmingham: Packt publishing Ltd. p. 133. " ...
"34 Selenium". Retrieved 2008-09-12. "14 Silicon". Retrieved 2008-09-12. " ...
"Robot Selenium Library". Retrieved March 23, 2018. "Robot Framework Broswe". Retrieved August 5, 2020. ... Emery Usage of Robot Framework in Automation of Functional Test Regression by Stanislav Stresnjak and Zeljko Hocenski Selenium ...
P. W. Schenk (1963). "Sulfur, Selenium, Tellurium". In G. Brauer (ed.). Handbook of Preparative Inorganic Chemistry, 2nd Ed. 1 ... ISBN 978-0-08-037941-8. P. W. Schenk (1963). "Sulfur, Selenium, Tellurium". In G. Brauer (ed.). Handbook of Preparative ...
... selenium and polonium: Tellurium and selenium compounds are similar. Tellurium exhibits the oxidation states −2, +2, +4 and +6 ... Tellurium and selenium are the heavy elements most depleted by this process. Tellurium is sometimes found in its native (i.e., ... Mixtures of selenium and tellurium are used with barium peroxide as an oxidizer in the delay powder of electric blasting caps. ... In contrast to selenium, tellurium does not usually replace sulfur in minerals because of the great difference in ion radii. ...
Selenium sensors generate enough voltage for direct connection to a meter; they need no battery to operate and this made them ... Selenium sensors however cannot measure low light accurately (ordinary lightbulbs can take them close to their limits) and are ... Selenium and silicon light meters use sensors that are photovoltaic: they generate a voltage proportional to light exposure. ... Selenium meter Photometer , Photodetector Colorimetry , Photometry , Radiometry Light value Photomultiplier tubes for detecting ...
Tellurium and selenium". Journal of Chemical Education. 9 (3): 474. Bibcode:1932JChEd...9..474W. doi:10.1021/ed009p474. Weeks, ...
Opuntia contains selenium. The red color of the fruit and juice is due to betalains, (betanin and indicaxanthin). The plant ... Bañuelos GS, Fakra SC, Walse SS, Marcus MA, Yang SI, Pickering IJ, Pilon-Smits EA, Freeman JL (January 2011). "Selenium ... Accumulation, Distribution, and Speciation in Spineless Prickly Pear Cactus: a Drought- and Salt-Tolerant, Selenium-Enriched ...
By researching the physics of selenium and selenium appliances, was the first to explain the abnormalities in selenium and ... АН Аз.ССР, Bakı, Azərb.SSR Elmlər Akademiyası Nəşriyatı, 1958, 204 c. Physical Processes Occurring in Selenium and Selenium ... ССР., 1973 Physical Properties of Selenium and Selenium Devices. Abdullayev G.B. Elm, Baku(1974). Физические свойства селена и ... Элм», 1974 Selenium Fritter. Abdullayev G.B., İnst.of Phys.Azerb Ac of Science, Baku, 1974, Фриттер селеновый. Абдуллаев Г.Б. и ...
selenium deficiency selenosis Cobalt none NE; NE Trace Required in the synthesis of vitamin B12, but because bacteria are ... "Selenium-Fact Sheet for Health Professionals". National Institutes of Health. 2016.. *^ Overview of Dietary Reference Intakes ... Selenium 00000.0550.055 0.4; 0.3 Trace Essential to activity of antioxidant enzymes like glutathione peroxidase Brazil nuts, ...
Broad beans (Amharic: baqella) are one of the most popular legumes in Ethiopia. They are tightly coupled with every aspect of Ethiopian life. They are mainly used as an alternative to peas to prepare a flour called shiro, which is used to make shiro wot (a stew almost ubiquitous in Ethiopian dishes). During the fasting period in the Ethiopian Orthodox Church tradition called Tsome Filliseta, Tsome arbeå, Tsome Tahsas, and Tsome Hawaria (which are in August, end of February-April, mid-November-beginning of January and June-July), two uncooked spicy vegetable dishes are made using broad beans. The first is Hilibet, a thin, white paste of broad bean flour mixed with pieces of onion, green pepper, garlic, and other spices based on personal taste. The second is siljo, a fermented, sour, spicy thin yellow paste of broad bean flour. Both are served with other stews and injera (a pancake-like bread) during lunch and dinner. Baqella nifro (boiled broad beans) are eaten as a snack during some holidays ...
Selenium 1817 J. Berzelius and G. Gahn 1817 J. Berzelius and G. Gahn While working with lead they discovered a substance that ... "34 Selenium". Retrieved 2008-09-12.. *^ "14 Silicon". Retrieved 2008-09-12. ... Shortly after the discovery of rubidium, Crookes found a new green line in a selenium sample; later that year, Lamy found the ...
Das and Kaplan nicely summarizes most of the data available on the use of PC-SPES, selenium, and vitamin E by prostate cancer ... Whether selenium supplementation will assume any role in prostate cancerprevention in patients who live in high-selenium areas ... Outside of aclinical trial, for patients who live in selenium-poor areas, low-levelsupplementation of selenium is a reasonable ... Selenium and Vitamin E Supplementation. Importantly, we need to tell patients that, to date, no controlled,prospective study ...
"Definition: selenium sulfide from Online Medical Dictionary".. *^ "DrugBank: DB00971 (Selenium Sulfide)". Archived from the ... Selenium disulfide, also known as selenium sulfide, is a medication used to treat pityriasis versicolor, seborrhoeic dermatitis ... Selenium monosulfide, along with elemental selenium and sulfur, has been used in medicinal preparations in the past,[14] ... Selenium disulfide has a composition that approximates to SeS2 and is sometimes called selenium sulfide. However, as used in ...
"Selenium intake and serum selenium in Finland: effects of soil fertilization with selenium" (PDF). American Journal of Clinical ... In Finland, selenium salts are added to chemical fertilizers, as a way to increase selenium in soils. Dietary supplements may ... In areas where selenium deficiency in livestock is a concern, selenium (as selenite) may be supplemented in feed. In some ... Xia, Y; Hill, KE; Byrne, DW; Xu, J; Burk, RF (2005). "Effectiveness of selenium supplements in a low-selenium area of China". ...
Selenium. The role of selenium in human metabolic processes. Selenium deficiency. The influence of diet on selenium status. ... Criteria for assessing selenium requirements. Recommended selenium intakes. Future research. References. The role of selenium ... Selenium deficiency. Non-endemic deficiencies of selenium. Biochemical evidence of selenium depletion (e.g., a decline in blood ... Selenium and human lactation in Australia: milk and blood selenium levels in lactating women and selenium intake of their ...
Selenium is a trace mineral needed in small amounts for good health, but exposure to much higher levels can result in ... Occupational inhalation exposure to selenium vapors may cause dizziness, fatigue, irritation of mucous membranes, and ... People may be exposed to low levels of selenium daily through food and water. ... How can selenium affect my health?. Selenium has both beneficial and harmful effects. Low doses of selenium are needed to ...
0 Seguidores Postado em 25 set 2009 3 Seguidores Dicas de Depuração em Falhas de Testes com Selenium por Chris Sims Chris Sims ... Notícias sobre Selenium Seguidores Appium agora suporta teste de aplicações Android nativas, híbridas e web por Abel Avram Abel ... Seguidores Selenium 2: além do WebElement por André Schaffer André Schaffer Seguir 0 Seguidores Postado em 17 jun 2014 ... 0 Seguidores Postado em 04 mar 2013 Seguidores Selenium 2: união com WebDriver, API otimizada e maior integração com browsers ...
... is one of many important dietary minerals, and we require a small amount of selenium in our daily diet. Selenium is ... The selenium content of plant foods is often closely related to selenium content of soil in which the plants have been grown. ... Selenium content of soils can vary widely, including in the U.S. However, poor soil content of selenium is not typically a ... Regardless of whether selenium deficiency is associated with increased risk of cancer, it is clear that good selenium nutrition ...
Exposure to selenium hexafluoride can cause irritation of the respiratory airway, skin and eyes. Exposure to high levels can ... Selenium hexafluoride has not been found in any of the 1,585 National Priorities List sites identified by the Environmental ... Significant exposure may occur only if you work with selenium hexafluoride. It is unlikely that the general population will be ... Workers that use selenium hexafluoride as a gaseous electric insulator or use selenium hexafluoride to produce other selenium ...
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It is important to note that infants should not receive selenium supplementation. ... The role of selenium in health was first recognized as a toxic one, by the recognition of its adverse effects. Being a trace ... In contrast to the normal plants selenium content of 10 ppm, even when they grow on selenium-rich soil, selenium accumulators ... Toxic levels of selenium. Some agencies have put forward a chronic reference exposure level of 0.02 mg/m3 for selenium and its ...
Selenium is a group 16 element with the atomic number 34. It is a metalloid, and shares several of its properties with oxygen ... An overview of the uses of selenium. Selenium is part of the unique group of compounds which are called semiconductors. It ... Selenium is also an important trace element in food, and is a vital part of many enzymes that take part in redox reactions. ... Selenium is a group 16 element with the atomic number 34. It is a metalloid, and shares several of its properties with oxygen ...
Selenium Sulfide: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Selenium sulfide comes in a lotion and is usually applied as a shampoo. As a shampoo, selenium sulfide usually is used twice a ... Selenium sulfide is for external use only. Do not let selenium sulfide get into your eyes, nose, or mouth, and do not swallow ... Before using selenium sulfide,. *tell your doctor and pharmacist if you are allergic to selenium sulfide or any other drugs. ...
... of Selenium 3.0 About This Video Use real-world example to explore the power of using Selenium Practical use of Selenium to ... resolve web automated testing … - Selection from Optimizing Selenium Test Performance [Video] ... The Selenium WebDriver API is fully object-oriented as opposed to the deprecated Selenium RC. The WebDriver API provides multi- ... Use real-world example to explore the power of using Selenium. *Practical use of Selenium to resolve web automated testing ...
sel = WWW::Selenium-,new( %args ). Constructs a new WWW::Selenium. object, specifying a Selenium Server host/port, a command to ... WWW::Selenium - Perl Client for the Selenium Remote Control test tool. SEE ALSO For more information about Selenium Remote ... sel-,shut_down_selenium_server(). Kills the running Selenium Server and all browser sessions. After you run this command, you ... The Selenium Server is a Java application.). Element Locators. Element Locators tell Selenium which HTML element a command ...
A list of US medications equivalent to Selenium is available on the website. ... Selenium is a medicine available in a number of countries worldwide. ... Hitrace Selenium (veterinary use). Nutritech, New Zealand. *Ivomec with Selenium for Sheep and Goats (Selenium and Ivermectin ( ... White-E (Selenium andTocopherol, α- (veterinary use)). Virbac, Australia. *White-E with Selenium (Selenium and Tocopherol, α- ( ...
... in Soils. Although Se is not an essential nutrient for plant growth, plants will take it up from the soil or through ... "Selenium for Dairy Cows," John Hibma, Farming, Dec. 2006, pgs. 20-21.. About the authors: Diane Schivera ([email protected]) is ... "Selenium Related Disorders in Washington Livestock," N.L. Gates and K.A. Johnson, Washington State Univ., ... Injectable forms of selenium called Mu-Se and Bo-Se are available also, with a prescription from a veterinarian. These are ...
... selenium disulfide, selenium disulphide, selsun blue, selenium iv disulfide, selenium sulfide ses2, sebusan, selenex, selenix, ... selenium disulfide, selenium disulphide, selsun blue, selenium iv disulfide, selenium sulfide ses2, sebusan, selenex, selenix, ... selenium oxydichloride, seleninyl dichloride, selenium chloride oxide, hsdb 678, selenium chloride oxide secl2o, selenium iv ... selenium iv dioxide 1:2, selenium oxide se2o4 PubChem CID: 24007 IUPAC Name: selenium dioxide SMILES: O=[Se]=O ...
We will discuss Selenium in an open forum setting in the context of Quality Assurance. I am starting this group to bring Denver ... This is a group for people interested in Selenium Automation. ...
... * 1. SAY "NO" TO MORE SELENIUM TESTS Anand Bagmar Test Practice Lead Bhumika Srinivas Lead ... to understand and build the testing pyramid and how it enables us to build the right testing framework with fewer Selenium, i.e ...
... As efficient as your in-house team We provide the people, the ability and the tools ... WebDriver & Selenium-Server Some reasons to use the Selenium-Server with Selenium-WebDriver. 0 You are using Selenium-Grid to ... 7. Selenium IDE * 8. Script Syntax 0 Selenium scripts that will be run from Selenium-IDE are stored in an HTML text file format ... Introduction to Selenium Web Driver by Return on Intelli... 41974 views * Automation Testing using Selenium by Naresh ...
Selenium is a naturally occurring trace element that can become concentrated and released by industrial, agricultural, ... Selenium Assessment in Aquatic Ecosystems will interest field scientists, natural resource managers, risk assessors and ... Selenium is a naturally occurring trace element that can become concentrated and released by industrial, agricultural, ... Selenium Assessment in Aquatic Ecosystems. A Guide for Hazard Evaluation and Water Quality Criteria. ...
WWW::Selenium::Util contains utility functions to help use Selenium in your test scripts:. use WWW::Selenium::Util qw/server_is ... WWW::Selenium::Util - Utility code to help test using Selenium. FUNCTIONS server_is_running( $host, $port ). Returns true if a ... Module Version: 1.33 Source Latest Release: Test-WWW-Selenium-1.36 *NAME *VERSION *SYNOPSIS *NAME *FUNCTIONS *server_is_running ... running/; use Test::More; if (server_is_running) { plan tests =, 1; } else { plan skip_all =, No selenium server found!; exit ...
Selenium is an antioxidant, helping to prevent free-radical damage. It is also essential for proper functioning of the thyroid ... Selenium. Learn the benefits, how much to take, drug interactions and which foods are full of selenium.. * ... Selenium is an antioxidant, helping to prevent free-radical damage. It is also essential for proper functioning of the thyroid ... Foods: High-selenium yeast; nuts, especially Brazil nuts; shrimp; tuna; turkey; chicken; and whole grains. ...
Selenium content in the tested products ranged from 0.9 to 24.5 μg/100 g. The average content of selenium in products based on ... The content of selenium in food is varied. Due to the fact that selenium is present in organisms in combination with proteins, ... As selenium deficiencies in celiac disease are observed, the aim of the study was to determine the selenium content in 27 grain ... The mean content of selenium in selected products is presented in Table 3. The content of selenium ranged from 0.9 μg/100 g ( ...
Selenium testing professional must have basic knowledge of Java Concepts and Selenium IDE. To learn the Selenium you can enrol ... Automation testing - Codeless Selenium By Infocampus. See all Articles by Infocampus hrGet Updates on Coach TrainingGet Updates ... Be that as it may, you can simply take in selenium training in Bangalore, an apparatus to mechanize an experiment. You can ... At Infocampus, selenium classes are focused on examples and real time projects with practicals. Contact 9738001024 or visit ...
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Life Extension, Super Selenium Complex & Vitamin E, 200 mcg, 100 Vegetarian Capsules. ... Eidon Mineral Supplements, Ionic Minerals, Selenium, Liquid Concentrate, 2 oz (60 ml). ... Trace Minerals Research, Ionic Selenium, 300 mcg, 2 fl oz (59 ml). ...
Retiring contaminated farmland in the Central Valley would keep selenium out of the Delta and save water. ...
Periodic Table of the Elements: SeleniumAtomic Number:34Atomic Symbol:Se SeleniumAtomic Weight:78.96ElectronConfiguration:2 · 8 · 18 ·
... and automated test suite using Selenium WebDriver In Detail Selenium WebDriver is a global leader in automated web testing. It ... empowers users to perform complex testing … - Selection from Selenium Design Patterns and Best Practices [Book] ... A. Getting Started with Selenium * Setting up the computer * Using Command Line Interface * Using the terminal on Windows * ... Selenium WebDriver is a global leader in automated web testing. It empowers users to perform complex testing scenarios with its ...
  • Selenium deficiency is relatively rare in healthy well-nourished individuals. (
  • citation needed] Selenium deficiency in combination with Coxsackievirus infection can lead to Keshan disease, which is potentially fatal. (
  • Selenium deficiency also contributes (along with iodine deficiency) to Kashin-Beck disease. (
  • Selenium is also necessary for the conversion of the thyroid hormone thyroxine (T4) into its more active counterpart, triiodothyronine, and as such a deficiency can cause symptoms of hypothyroidism, including extreme fatigue, mental slowing, goiter, cretinism, and recurrent miscarriage. (
  • People dependent on food grown from selenium-deficient soil may be at risk for deficiency. (
  • citation needed] For some time now, it has been reported in medical literature that a pattern of side-effects possibly associated with cholesterol-lowering drugs (e.g., statins) may resemble the pathology of selenium deficiency. (
  • In some regions (e.g. much of the northeastern and northwestern US and adjacent Canada, and the southeastern US), selenium deficiency in some animal species is common unless supplementation is carried out. (
  • Selenium deficiency is responsible (either alone or together with vitamin E deficiency) for many of the cases of WMD ("white muscle disease"), evidenced at slaughter or during necropsy by whitish appearance of striated muscle tissue due to bleaching by peroxides and hydroperoxides. (
  • In areas where selenium deficiency in livestock is a concern, selenium (as selenite) may be supplemented in feed. (
  • The GSHPx enzymes of liver and blood plasma fall in activity rapidly at early stages of selenium deficiency. (
  • In contrast, a form of GSHPx associated specifically with phospholipid-rich tissue membranes is preserved against selenium deficiency and is believed to have broader metabolic roles (e.g., in prostaglandin synthesis) ( 6 ). (
  • Three types of these iodothyronine deiodinases, differing both in tissue distribution and sensitivity to selenium deficiency, have been characterised. (
  • Regardless of whether selenium deficiency is associated with increased risk of cancer, it is clear that good selenium nutrition is important for antioxidant protection and for other health reasons as well. (
  • Selenium deficiency was found to result in white muscle disease in young animals, pancreatic necrosis in chickens, ulcers of the esophagus and stomach in wine, stillbirth and resorption of embryos in sheep, and abnormal sperm motility in sheep. (
  • In the US, Selenium (selenium sulfide topical) is a member of the drug class minerals and electrolytes and is used to treat Vitamin/Mineral Supplementation and Deficiency . (
  • Selenium deficiency is rare worldwide, and it often takes years to develop. (
  • Taking selenium by mouth is effective for preventing selenium deficiency. (
  • There is no widely recognized deficiency syndrome for selenium, unlike the syndromes associated with calcium or magnesium (hypocalcemia and hypomagnesemia, respectively). (
  • This fact has given rise to a theory that selenium deficiency is a common cause of cancer, and that selenium supplements can reduce this risk. (
  • People at risk for selenium deficiency include those undergoing kidney dialysis, which removes selenium from the blood, and those living with HIV. (
  • Keshan cardiomyopathy and Kashin-Beck osteoarthropathy are diseases occurring specifically in areas of selenium deficiency in Asia. (
  • The clinical syndrome that results from selenium (and Vitamin E) deficiency is called white muscle disease. (
  • Laboratory tests are available to diagnose selenium deficiency. (
  • These losses could increase the worldwide prevalence of selenium deficiency. (
  • Yet, they added, the risk of selenium deficiency in the U.S. is negligible. (
  • Because published literature suggests an association between a relative deficiency of selenium and diabetes, the investigators examined diabetes risk by baseline plasma selenium level. (
  • What are the symptoms of a selenium deficiency? (
  • It is important to note that infants should not receive selenium supplementation. (
  • These were all found to be treatable by selenium supplementation, which was especially rewarding since these diseases had, up to that time, had no cure. (
  • There is no evidence that selenium supplementation of the U.S. population would be helpful," says Raymond F. Burk, MD, a professor of medicine at Vanderbilt University in Nashville, Tenn. (
  • Thus, based on present knowledge I would not recommend selenium supplementation," says Burk, who studies the health effects of selenium. (
  • A summary report of the NPC Trial published in Cancer Epidemiology Biomarkers & Prevention in July 2002 revealed benefits of selenium supplementation on cancer incidence, particularly among men with low blood selenium concentration. (
  • The selenium-CVD association was a secondary endpoint in the Nutritional Prevention of Cancer Trial, which was designed primarily to determine if selenium supplementation could prevent the recurrence of non-melanoma skin cancer. (
  • Results of the trial, the only large randomized clinical trial to date to examine selenium supplementation alone in the prevention of CVD, appear in the April 15 issue of the American Journal of Epidemiology. (
  • Our findings are consistent with those from previous studies that have shown no beneficial effect of selenium supplementation in combination with other antioxidants on the primary prevention of cardiovascular disease. (
  • Results showed no association between selenium supplementation on any of the endpoints studied: coronary heart disease, stroke or deaths from cardiovascular disease, Stranges said. (
  • However, this report adds important information to our knowledge on the role of selenium in cardiovascular-disease prevention, indicating no overall benefit of supplementation by selenium alone in prevention of cardiovascular disease. (
  • This function of selenium led researchers to investigate whether or not selenium supplementation can be used to reduce cardiovascular disease. (
  • However, current evidence from intervention trials in selenium-replete participants does not support a protective effect of selenium supplementation against cancer. (
  • Preliminary evidence from randomized controlled trials suggests that selenium supplementation may prevent viral load progression and increase immune cell count in HIV -positive patients. (
  • Making the final step linking high selenium intake, supplementation, and high cholesterol, the scientists noted that among the participants, 48.2 per cent admitted they regularly took dietary supplements. (
  • Dr Saverio Stranges said high levels of selenium were not exclusively caused by supplementation, but the conclusions of the study do raise concerns given the increased use of selenium supplements in recent years. (
  • Keep in mind that some herbs contain high amounts of selenium, so, taking these herbs together with selenium supplementation could produce selenium accumulation poisoning. (
  • Explain to interested patients that this study found that selenium supplementation does not reduce the risk of diabetes. (
  • Explain that most people in this country receive adequate selenium from their diet and supplementation may put them at risk of diabetes. (
  • COVENTRY, England, July 10 -- Selenium supplementation does not prevent diabetes and might actually precipitate it, a large prevention trial has suggested. (
  • Patients randomized to selenium supplementation had a type 2 diabetes incidence of 12.6 per 1,000 person-years versus 8.4 for those not receiving nutrient supplements, Saverio Stranges, M.D., Ph.D., of Warwick Medical School and University Hospital in Coventry, and colleagues at the U.S. Department of Agriculture, reported online ahead of Aug. 21 publication in the Annals of Internal Medicine . (
  • The study had its origin in preclinical data suggesting low-dose selenium supplementation has a favorable effect on glucose metabolism. (
  • As a result, selenium supplementation would be unlikely to increase antioxidant activity. (
  • They emphasized that the benefits of selenium supplementation are unproven, the mineral has a narrow therapeutic range, and it can be toxic. (
  • Focusing on the essential key mineral, selenium, the seminar presents world-renowned experts, Professor Peter Surai and Dr. Kevin Liu, sharing the latest global research and developments in selenium nutrition and supplementation. (
  • Event organiser, Trina Parker, Country Manager BEC Feed Solutions, says the seminar is a New Zealand-first, and a must for anyone interested in improved animal performance, enabling them to learn first-hand about some of the latest global developments in selenium supplementation. (
  • We're keen to raise awareness of the fact selenium is vital to animal health and production and therefore supplementation is essential. (
  • Attendees can expect to come away from the event armed with knowledge on the difference in selenium uptake, storage and deposition in milk, meat and eggs, how to improve the antioxidant status of NZ livestock, consequences of low selenium status in a New Zealand situation, and overall benefits of effective selenium supplementation. (
  • Studies in Jiangsu Province of China have indicated a reduction in the prevalence of these diseases by taking selenium supplements. (
  • Dietary supplements may utilize sodium selenite, L-selenomethionine or selenium-enriched yeast. (
  • Bruce Hoskins of the Maine Soil Testing Service does not recommend Se fertilization but suggests that livestock producers feed the animals supplements, or buy in soy meal, alfalfa meal or grains produced in the West, where soils are high in selenium. (
  • This article looks at the potential health benefits of selenium when a person consumes it from food or supplements, the recommended daily intake of selenium, and some possible health risks associated with selenium. (
  • However, more research is underway to help inform how selenium supplements might support thyroid health. (
  • Other studies cited in a 2018 review indicate that selenium supplements may have little effect on cancer risk. (
  • However, although selenium has links with many aspects of human health, there is not enough evidence to indicate that taking selenium supplements can prevent any of these conditions. (
  • However, clinical evidence does not support the use of selenium supplements for this purpose. (
  • Evidence from studies is mixed , however, and selenium supplements are not yet prescribed for people at risk of diseases such as Alzheimer's, although it may have a role in prevention that is still under investigation . (
  • More studies are under way to decide whether selenium supplements might support thyroid health. (
  • In response to their new findings, a research team has recommended that U.S. residents stop taking supplements that contain selenium. (
  • Given the current diabetes epidemic, the high selenium intake from naturally occurring selenium in U.S. soil and the popularity of multivitamin/mineral supplements containing selenium in the U.S., these findings call for a thorough evaluation of the risk and benefits associated with high selenium status in the U.S.," the researchers wrote in a study published online in Environmental Health Perspectives on May 15. (
  • Furthermore," they wrote, "our findings suggest that selenium supplements should not be used in the U.S. until there is a better understanding of their potential risks and benefits. (
  • Supplements containing selenium have gained popularity in the United States because of anti-cancer claims, and selenium levels in people have been rising. (
  • Nearly one-quarter of Americans over the age of 40 take selenium supplements or multivitamin supplements that include selenium. (
  • According to the U.S. Food and Drug Administration, selenium supplements are generally unnecessary because "normal consumption of food and water" provides adequate amounts. (
  • I would never, ever, ever take supplements with selenium in it,' said Judith Stern, a professor of nutrition and internal medicine at University of California at Davis. (
  • Maria Boosalis, director of clinical nutrition at the University of Kentucky's College of Health Sciences, recommended in a published report last year that 'the indiscriminate use of selenium supplements should be approached with caution' until long-term health studies are conducted. (
  • The authors found instead that people who took 200 microgram selenium supplements each day for almost eight years had an increased risk of developing the disease. (
  • There's new evidence to suggest that selenium supplements aren't necessary for most Americans. (
  • And a few studies included in the review suggest that taking more selenium in supplements may increase the risk for type 2 diabetes , though evidence is conflicting on that point. (
  • Selenium Supplements: Too Much of a Good Thing? (
  • Hoping that more selenium might add up to even better health, researchers have tested supplements to see if they might boost immune function, brain health, and fertility , and ward off cancer and heart disease and stroke risk. (
  • The review found that for people who have low selenium levels, taking supplements sometimes helps. (
  • One study of adults in the U.K. who had low selenium levels, which are more common in Europe, found that people who took supplements were able to fight off a virus more quickly than those who took a placebo. (
  • And supplements boosted sperm quality in men with fertility problems who also had low selenium intakes, allowing 11% to father a child. (
  • Selenium supplements have also shown promise for thyroid problems , though researchers say those results are early and need to be confirmed. (
  • Studies in the U.S. that have tested supplements for cancer and heart disease protection have found no evidence of benefit, and indeed, in people who had the highest selenium levels going into the studies, taking supplements was tied to increased risks of harm. (
  • In addition, we also don't know if selenium supplements help every man or only some. (
  • If you are taking a selenium supplement, the maximum amount from food and supplements considered safe is 400 mcg a day. (
  • Naturopaths use selenium supplements to treat asthma, acne, tendinitis, infertility problems in men, and postmenopausal disorders in women. (
  • However, when the balance is altered and the body absorbs too much selenium, such as through taking selenium supplements, it can have adverse affects. (
  • Also, of the participants with the highest selenium levels, 48.2% admitted they regularly took dietary supplements. (
  • Dr Saverio Stranges said although high selenium levels were not exclusively caused by people taking dietary supplements, the results of the study were concerning because the use of selenium dietary supplements had risen considerably in the UK in recent years. (
  • He said: "This use has spread despite a lack of definitive evidence on selenium supplements efficacy for cancer and other chronic disease prevention. (
  • We believe that the widespread use of selenium supplements, or of any other strategy that artificially increases selenium status above the level required is unwarranted at the present time. (
  • As we will see, there is some preliminary evidence that selenium supplements might provide some protection against some types of cancer among people living in the US, but this evidence is far from definitive. (
  • The table below from the Office of Dietary Supplements provides a more complete list of the selenium content in certain foods and the percent daily value. (
  • The two general types of selenium supplements are available to consumers are organic and inorganic forms. (
  • 13,14 However, other research on both animals and humans suggests that selenite supplements are about as good as organic forms of selenium. (
  • 25-32,62 A large trial reported in 2007 reported that use of selenium supplements reduced viral load. (
  • For reasons that are not clear, another study found that selenium supplements decreased symptoms of psychological anxiety in patients undergoing highly active retroviral therapy (HAART). (
  • One study of healthy people in the UK (where marginally low selenium intake is common) found that use of selenium supplements improved general immune function, as measured by response to poliovirus immunization. (
  • Selenium is an interesting compound as it is classified as an essential nutrient so it appears in all kinds of health food supplements and yet there are severe limitations on the discharge of this compound. (
  • Selenium is listed as an ingredient in many multivitamins and other dietary supplements, as well as in infant formula, and is a component of the antioxidant enzymes glutathione peroxidase and thioredoxin reductase (which indirectly reduce certain oxidized molecules in animals and some plants) as well as in three deiodinase enzymes. (
  • MIAMI -- Selenium supplements appear to slow the progress of HIV, according to interim results of a study conducted here. (
  • Point out that this study suggests that selenium supplements may safely improve the immune function of patients with HIV. (
  • MIAMI, Jan. 22 -- Selenium supplements appear to slow the progress of HIV, according to interim results of a study conducted here. (
  • Selenium toxicity can be caused by regular consumption of Brazil nuts, which contain high levels of selenium, and from improperly formulated over-the-counter supplements. (
  • The most common forms of selenium in dietary supplements include selenomethionine, selenocysteine and selenite. (
  • The tolerable upper intake level ( UL ) for selenium is 400 μg/day for adolescents and adults and includes both selenium obtained from food, which averages about 100 μg/day for adults in the US, and selenium from supplements. (
  • Because some evidence suggests that high serum selenium concentrations may have adverse effects on glycemic control, individuals with high selenium status and/or those at risk for type 2 diabetes mellitus should avoid taking selenium supplements. (
  • Taking selenium supplements may increase cholesterol levels by as much as 10 per cent, according to a new study. (
  • The body naturally absorbs selenium from vegetables, meat, and seafood but it is also found in higher quantities in supplements. (
  • Selenium is an essential metal in cell culture that was not recognized in formulations developed prior to 1976 because sufficient quantities of the metal were present in the supplements, such as serum or in the water used to prepare media. (
  • In some instance selenium is now added to media based on the above formulations, it is a component of the supplements ITS, SPIT, SPITE series of supplements (see products below). (
  • Many different types of feeds and supplements contain selenium. (
  • If low selenium levels cause medical problems, and if AIDS patients have low selenium levels, why not load them up with selenium supplements? (
  • In 2003, along with Youngevity®, Dr. Wallach successfully petitioned the FDA to establish a Qualified Health Claim for selenium adding that it "may reduce the risk of certain cancers" to labels of dietary supplements containing Selenium. (
  • FRIDAY, Feb. 21, 2014 (HealthDay News) -- Men taking selenium or vitamin E supplements might double their risk of prostate cancer , depending on the levels of selenium already in their bodies, a new study suggests. (
  • Men who already have high concentrations of selenium in their bodies nearly double their risk of aggressive prostate cancer if they take selenium supplements , said lead author Dr. Alan Kristal, associate head of the Cancer Prevention Program at the Fred Hutchinson Cancer Research Center in Seattle. (
  • The new study, published Feb. 21 in the Journal of the National Cancer Institute , also found that vitamin E supplements can more than double a man's prostate cancer risk, but only if the man has low concentrations of selenium in his body. (
  • The upshot, said Kristal, is simple: Don't take high-dose selenium or vitamin E supplements. (
  • Researchers in this new study used toenail samples taken from SELECT participants to determine the level of selenium already in their bodies before taking the supplements. (
  • Taking selenium supplements increased the risk of high-grade cancer by 91 percent among men with already high selenium levels. (
  • Contradicting evidence from preclinical and observational studies, a mean follow-up of almost eight years showed that the diabetes risk more than doubled in those with the highest selenium levels at baseline who took supplements, compared with those who had the lowest baseline levels. (
  • In an editorial that accompanied the report, Eliseo Guallar, M.D., DrPH, of the Johns Hopkins Bloomberg School of Public Health, and co-authors there, pointed out that more than 1% of the U.S. population takes selenium supplements, and more than 35% take multivitamin and multi-mineral supplements that may contain it. (
  • By taking selenium supplements on top of an adequate dietary intake, people may increase their risk for diabetes. (
  • Designed primarily to assess the effects of selenium supplements on cancer risk, the trial involved 1,312 patients who were randomized to 200 µg/d of selenium or placebo and followed from 1983 through 1996. (
  • Ms Parker highlights the fact that interesting new research indicates selenium supplements currently available in NZ are not as bio-available to the animal as initially believed. (
  • Scientists have also reported an 11% increased risk of developing type 2 diabetes for people taking 200mcg a day of selenium supplements, according to a 2018 study in the European Journal of Epidemiology . (
  • When should I take selenium supplements? (
  • other metabolically active forms include selenotrisulphides and other acid-labile selenium compounds. (
  • Some selenium compounds will dissolve in water, and some will settle to the bottom as particles. (
  • Chronic oral exposure to high concentrations of selenium compounds can produce a disease called selenosis. (
  • Studies of laboratory animals and people show that most selenium compounds probably do not cause cancer. (
  • The International Agency for Research on Cancer (IARC) has determined that selenium and selenium compounds are not classifiable as to their carcinogenicity to humans. (
  • When released to air, selenium hexafluoride will react with moisture, forming other compounds which are removed from the atmosphere by rainfall. (
  • Workers that use selenium hexafluoride as a gaseous electric insulator or use selenium hexafluoride to produce other selenium containing compounds may be exposed to this gas. (
  • Long-term exposure to low concentrations of selenium hexafluoride may cause effects similar to exposure to other selenium or fluoride compounds, such as pale appearance, nervousness, depression, gastrointestinal problems, lack of appetite, weight loss, and dental defects. (
  • The inhalation of selenium compounds causes respiratory membrane irritation, pulmonary edema, bronchial inflammation and pneumonia. (
  • Other toxic compounds are selenium dioxide, sodium selenite and selenium sulfide. (
  • Selenium is part of the unique group of compounds which are called semiconductors. (
  • TWA 0.2 mg/m 3 [*Note: The REL also applies to other selenium compounds (as Se) except Selenium hexafluoride. (
  • Some selenium compounds are gases. (
  • Selenium and its compounds are used in some important because exposure to selenium at high photographic devices, gun bluing (a liquid solution levels may harm you and because these sites may be used to clean the metal parts of a gun), plastics, sources of exposure. (
  • Estimates of the average may then react with water to form soluble selenium intake of selenium from food for the U.S. compounds. (
  • Selenium is below sulfur on the periodic chart so it forms many of the same compounds. (
  • DNA damage-mediated apoptosis induced by selenium compounds. (
  • Selenium (Se) compounds, which are the most extensively studied cancer chemopreventive agents, induce apoptotic death of tumor cells. (
  • SeCl4 is used in the synthesis of other selenium compounds. (
  • Selenium is one of many important dietary minerals, and we require a small amount of selenium in our daily diet. (
  • The amount of selenium in food depends on the concentration of the soil and water where it grew. (
  • The amount of selenium in grains and grain-based foods depends on the soil content where they grew. (
  • The amount of selenium in food depends on where it is grown or raised. (
  • The amount of selenium in soils varies a lot around the world, which means that the foods grown in these soils also have differing selenium levels. (
  • Although this amount of selenium is adequate, it is below the average daily intake in the U.S., which is 125 mcg. (
  • The amount of selenium in the diet is influenced by its level in the soil. (
  • Like iodine, the amount of selenium in any particular food depends on how much selenium was present at the source of production. (
  • Similarly, the levels of selenium in the food consumed by an animal impacts the amount of selenium present in that animal product. (
  • The influence of chemicals on the cultivation land determines the amount of selenium in the soil, which indirectly determines the amount of selenium entering our body system. (
  • They then re-analyzed the data to see if the amount of selenium already present in the body made any difference when it came to prostate cancer risk. (
  • The role of selenium in the cytosolic enzyme glutathione peroxidase (GSHPx) was first illustrated in 1973. (
  • The role of selenium in health was first recognized as a toxic one, by the recognition of its adverse effects. (
  • These findings fueled more intensive investigation into the role of selenium in various body processes. (
  • So far based on the evidence of animal and epidemiological studies, the role of selenium and cancer is probably the most significant for prostate cancer. (
  • The role of selenium in human nutrition and other therapeutic applications has provoked intense controversy over the past two decades. (
  • The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities. (
  • Insoluble forms of selenium will remain in soil, but soluble forms are very mobile and may enter surface water from soils. (
  • Levels of these forms of selenium that would be necessary to produce such effects are normally not seen outside of the workplace. (
  • Injectable forms of selenium called Mu-Se and Bo-Se are available also, with a prescription from a veterinarian. (
  • There are two forms of selenium: organic and inorganic. (
  • Some research suggests that selenite is harder for the body to absorb than organic forms of selenium, such as selenomethionine (selenium bound to methionine, an essential amino acid) or high-selenium yeast (which contains selenomethionine). (
  • The plants convert inorganic forms of selenium to organic making it available for humans. (
  • The levels and chemical forms of selenium in plant-based food vary according to the composition and selenium content of soil in which the plants are grown. (
  • In addition to the activity of glutathione peroxidase, selenium-containing enzymes are involved in recycling of vitamin C from its spent form back to its active one, allowing for greater antioxidant protection. (
  • Selenium is an antioxidant which seems to inhibit cell proliferation. (
  • Selenium is an antioxidant, helping to prevent free-radical damage. (
  • Selenium is an essential element and antioxidant, but medical experts say there is a fine line between the amount that the body needs and the amount that is harmful. (
  • Because it boosts the body's antioxidant capacity, selenium is thought to have some ability to control cell damage that may lead to cancer. (
  • Selenium is an essential trace mineral that acts as an antioxidant and supports numerous functions in the body. (
  • The antioxidant benefits of selenium are integral to its effects on the body. (
  • Selenium is an antioxidant and antioxidants help maintain cellular health by protecting the body from free radicals. (
  • Selenium enhances the antioxidant properties of vitamin E . It is also a component of an important antioxidant enzyme called glutathione peroxidase. (
  • BUFFALO, N.Y. -- Selenium does not protect against cardiovascular disease, despite its documented antioxidant and chemopreventive properties, analysis of a randomized placebo-controlled clinical trial covering 13 years has shown. (
  • One possibility is that selenium -- an antioxidant -- may repair damage done to immune cells by reactive oxygen species, which are higher in people with HIV. (
  • Impaired antioxidant protection in selenium-deficient individuals may affect physiological responses to stress. (
  • Selenium is considered a health ingredient because of its antioxidant properties, and the perception that it can reduce cancer risks. (
  • Doctors haven't sorted out yet whether low selenium levels contribute directly to AIDS deaths or merely correlate with them, but our bodies use selenium as an antioxidant, and a lack of antioxidants puts stress on cells. (
  • An estimated 99% of the U.S. population has plasma selenium levels that are more than 95 ng/mL, although selenium-driven antioxidant activity plateaus at plasma selenium levels of 70 to 90 ng/mL. (
  • Attendees will learn first-hand about the importance of selenium as an antioxidant in modern New Zealand intensive animal production. (
  • Selenium is an antioxidant, which means it helps protect our cells and tissues from damage caused by an excess of free radicals, caused by smoking or pollution, for example. (
  • 2. Tinggi U. Selenium: its role as antioxidant in human health. (
  • Selenium is a potent antioxidant which guards the cells from free radical damage. (
  • The Selenium WebDriver API is fully object-oriented as opposed to the deprecated Selenium RC. (
  • The WebDriver project began with the aim to solve the Selenium' pain-points. (
  • 0 2008 - merging of Selenium and WebDriver. (
  • Selenium had massive community and commercial support, but WebDriver was clearly the tool of the future. (
  • Selenium WebDriver is a global leader in automated web testing. (
  • Experience with an automation testing tool such as Selenium WebDriver, Junit, SOAPUI, QTP, or Cucumber and performing results analysis. (
  • We offer Linux based (both Headless and with Graphical User Interface) as well as Windows based solutions for Selenium Webdriver, Selenium Remote Webdriver and Selenium Grid. (
  • Browse other questions tagged selenium selenium-webdriver xpath mousehover webdriverwait or ask your own question . (
  • Introduction: What Is Selenium WebDriver? (
  • Selenium WebDriver is a tool used for automating Web application testing. (
  • WebDriver is the successor to Selenium RC, which accepts commands and sends them to a browser. (
  • Selenium WebDriver APIs are platform independent and support different programming languages such as C#, Java, Perl, PHP, and Ruby. (
  • In this tutorial, I will provide instructions on how to set up Selenium WebDriver using Microsoft Visual Studio and give you an example to explain how to write a quick test using WebDriver. (
  • The Selenium WebDriver setup process is pretty much the same across different versions of Visual Studio: Visual Studio 2013, Visual Studio 2015, and Visual Studio 2017. (
  • A developer can either download Selenium WebDriver by clicking this link, or they can add the references from the NuGet package. (
  • Select Selenium.webdriver and click Install. (
  • Selenium WebDriver is a powerful tool to automate your mundane browser testing tasks. (
  • Selenium WebDriver makes direct calls to the browser by using each browser's native support for automation. (
  • I hope this article has provided a basic understanding about Selenium WebDriver automation. (
  • Selenium Grid was used with RC to test multiple tests on remote machines.Nowadays,as people find Webdriver better than RC,hence Grid works with both Webdriver and RC. (
  • Selenium Webdriver is an enhanced version of Selenium Rc and the most tool.It accepts commands via client API and sends them to browsers.Simply put,Selenium Webdriver is a browser specific driver which helps in accessing and launching the different browsers.It provides an interface to write and run automation scripts.Every browser has different drivers to run tests. (
  • As mentioned earlier,Selenium has a suite of tools,so it suits every need of the users.You can use various tools like WebDriver,Grid,IDE for fulfilling your different needs. (
  • Studies in the International Journal of Endocrinology and Nature Reviews Endocrinology suggest that having an optimal level of selenium in the body may help prevent thyroid disorders. (
  • He estimated, however, that the level of selenium that Simplot says causes a 20 percent rate of deformity actually causes a deformity rate of a minimum of 70 percent of all fry. (
  • There also was no difference in the endpoints based on the level of selenium at baseline. (
  • The FDA has set a daily recommended level of selenium for an "average" horse at a total of 3 mg per day. (
  • The level of selenium in the blood of AIDS patients is very strongly linked to the likelihood of death-low selenium levels means the person is doomed. (
  • Fish, grass-fed and pasture-raised meats, whole grains, and nuts and seeds are either good, very good, or excellent food sources of selenium. (
  • We rate nine of the World's Healthiest Foods as excellent sources of selenium. (
  • Probably, if you've read about food sources of selenium, you've read about Brazil nuts as a strong source of the mineral. (
  • As a more general rule of thumb, we can identify the best sources of selenium by food group. (
  • Environmental sources of selenium (Se) such as from organic-enriched sedimentary deposits are geologic in nature and thus can occur on regional scales. (
  • They'll also be given an insight into the performance of different sources of selenium for both ruminant (dairy, beef, sheep and goats) and monogastric animals (pigs, layer hens, broilers, horses and pets). (
  • Which foods are the best sources of selenium? (
  • These diseases are most common in certain parts of China where the intake is low because the soil is extremely deficient in selenium. (
  • Depending on where they are grown, this is likely to be true-one ounce of Brazil nuts may contain as much as 10 times the Dietary Reference Intake (DRI) recommendation for selenium intake. (
  • The long-term intake of excessive selenium may involve either organic or inorganic forms in food or water. (
  • Selenium that may be present in fossil intake of selenium from eating food, and to a lesser fuels combines with oxygen when burned, which extent, from water intake. (
  • In fact, studies show the average selenium intake for men in the U.S. is about 134 micrograms per day. (
  • In the following sections, we'll explore how selenium functions in the body, and which foods high in selenium may be added to your diet to ensure adequate intake. (
  • Most Americans consume adequate amounts of selenium daily, with an average daily intake of around 108 mcg. (
  • The tolerable upper level intake for selenium has been set at 400 mcg per day. (
  • Insufficient selenium intake has been estimated to affect up to 1 billion people worldwide. (
  • By comparison, the recommended daily intake of selenium for adults is 55 mcg, and recommended daily intake of vitamin E is about 22 IU, according to the U.S. National Institutes of Health. (
  • The selenium content of plant foods is often closely related to selenium content of soil in which the plants have been grown. (
  • Selenium content of soils can vary widely, including in the U.S. However, poor soil content of selenium is not typically a factor in the average U.S. diet, and the U.S. population 2 years and older averages over 100 micrograms of selenium per day. (
  • There are also many other plants which have the capability to concentrate selenium that is taken up from the soil, and they are termed selenium accumulators. (
  • In contrast to the normal plant's selenium content of 10 ppm, even when they grow on selenium-rich soil, selenium accumulators may have concentrations in thousands of ppm. (
  • Other selenium accumulators also exist, which can grow on selenium-poor soils, and these are secondary soil accumulators. (
  • This does not mean you should load your soil with selenium. (
  • A map of soil Se concentrations in the United States is posted at . (
  • It usually only occurs in regions with severely low selenium content in the soil, such as several regions in China. (
  • Selenium is an essential mineral found in varying concentrations in soil. (
  • It's found in foods such as Brazil nuts, sunflower seeds and garlic, but the amount in any given food depends on the selenium content of the soil in which it was grown. (
  • Airborne particles of selenium, such as population range from 71 to 152 millionths of a in ash, can settle on soil or surface water. (
  • Selenium occurs naturally in soil and leaches onto farm fields from irrigation and streams. (
  • Thanks to selenium-rich soil throughout much of the country, most Americans get plenty of this essential mineral through meats and grains like corn and wheat. (
  • Most selenium is absorbed from food products, whether plants grown in the soil or animals that have eaten the plants. (
  • Selenium levels in soil vary widely, not only in different countries but also across different regions. (
  • For example, in the United States the western states have higher levels of selenium in the soil than the eastern states. (
  • South Dakota has the highest rates of soil selenium in the United States, while Ohio has the lowest. (
  • Onions, garlic , mushrooms, broccoli, and Swiss chard may contain high amounts of selenium if they are grown in selenium-rich soil. (
  • For example, if the soil in which a fruit, vegetable, or grain was grown is rich in selenium, the plant will have higher selenium levels. (
  • Soil contains inorganic selenium, known as selenate and selenite. (
  • Plants draw selenium from the soil and convert it into organic selenium, known as selenomethionine and selenocysteine. (
  • However, in some parts of China where the soil is depleted of selenium, the incidence of various types of cancer is much higher than in the rest of the country. (
  • Selenium content of food varies depending on the selenium content of the soil in which it was grown. (
  • Selenium is a trace mineral found in soil and naturally present in many foods. (
  • Although higher plants do not appear to require selenium for survival, they can incorporate it non-specifically into sulfur-containing molecules when the mineral is present in the soil (1) . (
  • Certain "indicator" plants may reveal high levels of soil based selenium (such as locoweed), and are common in areas such as Colorado and New Mexico. (
  • As previously mentioned, Florida is typically considered selenium deficient or adequate soil, depending on the region. (
  • Dietary selenium availability is controlled by soil-plant interactions, but the mechanisms governing its broad-scale soil distributions are largely unknown. (
  • We used 33,241 soil data points to model recent (1980-1999) global distributions of Selenium (Se), an essential trace element that is required for humans. (
  • Selenium levels in the soil vary between countries, and are in decline - countries with already low levels include Scotland, Germany and Denmark. (
  • You should be able to get all the selenium you need from eating a balanced diet but if you live in Scotland, or another country with low levels of selenium in the soil, you could consider a supplement. (
  • Selenium is a naturally occurring mineral element that is distributed widely in nature in most rocks and soils. (
  • Selenium occurs naturally in the environment and can be released by both natural and manufacturing processes. (
  • Selenium is a naturally occurring trace element that can become concentrated and released by industrial, agricultural, petrochemical and mining activities. (
  • 2 That being said, unless you're taking a supplement, it's difficult to "overdose" on selenium that's naturally occurring in foods. (
  • Selenium is a naturally occurring, solid substance _______________________________________ that is widely but unevenly distributed in the earth's crust. (
  • Selenium occurs naturally in the environment. (
  • People in these regions naturally take in about 60 to 90 mcg of selenium per day from their diet. (
  • Selenium is a naturally occurring trace mineral that is vital to good health. (
  • The body naturally absorbs selenium from foods such as vegetables, meat and seafood. (
  • Selenium is a naturally occurring element that, when disturbed, can be released as a toxic byproduct of human activities like farming, mining and burning coal. (
  • Selenium is found naturally in a variety of different plant and animal foods. (
  • Selenium has seven naturally occurring isotopes. (
  • The legal limit for selenium, established in 1991, was based on human epidemiological studies of populations exposed to naturally occurring selenium in drinking water. (
  • Selenium is one of the rarest elements that are found naturally in the earth's crust. (
  • Selenium, a mineral found naturally in Brazil nuts, red meat, fish, and grains, became popular as a supplement in the late '90s because researchers believed it could help prevent prostate cancer. (
  • Brief exposures to high levels of elemental selenium or selenium dioxide in air can result in respiratory tract irritation, bronchitis, difficulty breathing, and stomach pains. (
  • Selenium forms two oxides: selenium dioxide (SeO2) and selenium trioxide (SeO3). (
  • Selenium tetrachloride can be reduced in situ to the dichloride using triphenylstibine: SeCl4 + SbPh3 → SeCl2 + Cl2SbPh3 Selenium tetrachloride reacts with water to give selenous and hydrochloric acids:[page needed] SeCl4 + 3 H2O → H2SeO3 + 4 HCl Upon treatment with selenium dioxide, it gives selenium oxychloride:[page needed] SeCl4 + SeO2 → 2SeOCl2 Lide, David R. (1998). (
  • Volunteers who were in the selenium group but did not achieve significantly higher serum levels of the metal were likely to skip their medication about 43% of the time, compared with about 14% of the time for responders. (
  • In Finland, selenium salts are added to chemical fertilizers, as a way to increase selenium in soils. (
  • Demonstrations of its essentiality to rats and farm animals were followed by appreciation that the development of selenium-responsive diseases often reflected the distribution of geochemical variables which restricted the entry of the element from soils into food chains. (
  • Values from 3 mg in New Zealanders to 14 mg in some Americans reflect the profound influence of the natural environment on the selenium contents of soils, crops, and human tissues. (
  • These plants are able to grow only on seleniferous soils, and are called primary selenium indicators. (
  • Exposure to selenium is primarily through food, and in some areas with seleniferous soils, through drinking water. (
  • Maine soils are generally very low in selenium. (
  • Selenium, as selenate, was ultimately found weathered with sulfur from marine sources in soluble sodium and magnesium sulfate salts, which are concentrated by evaporation on farmland soils. (
  • Foods containing significant and reliable amounts of selenium include animal products like meat, seafood, and dairy foods, as well as whole grains and other foods grown in selenium-rich soils, especially Brazil nuts. (
  • It's well known that New Zealand has low selenium soils, and because it's not essential for plant growth, this vital mineral is often over-looked. (
  • Selenium monosulfide, along with elemental selenium and sulfur, has been used in medicinal preparations in the past, [14] causing confusion and contradiction [15] as to exactly what form selenium is in any given topical preparation. (
  • Elemental selenium dust exposure also produces mucous membrane irritation, bleeding from the nose, and coughing, besides the other symptoms. (
  • Elemental selenium has low toxicity following oral administration. (
  • EPA has classified elemental selenium as a Group D, not classifiable as to human carcinogenicity, and selenium sulfide as a Group B2, probable human carcinogen. (
  • crystals, is often referred to as elemental selenium or selenium dust. (
  • This form of selenium is considerably less toxic than inorganic sodium selenite or elemental selenium. (
  • Although trace amounts of selenium are necessary for cellular function in many animals, including humans, both elemental selenium and (especially) selenium salts are toxic in even small doses, causing selenosis. (
  • [4] Selenium disulfide is an inorganic compound with the chemical formula SeS 2 . (
  • Chemically inorganic supplemental sources are sodium selenite and sodium selenate, which come as a trace mineral salt with selenium. (
  • Selenium is most commonly found in nature in its inorganic form, sodium selenite. (
  • The inorganic form of selenium, selenite, is essentially selenium atoms bound to oxygen. (
  • Selenium tetrachloride is the inorganic compound composed with the formula SeCl4. (
  • The consequences of a low selenium status on physiologic responses to a shortage of iodine are complex. (
  • As you'll see below in the Relationship with Other Nutrients section, selenium and iodine work together to keep thyroid function strong and consistent. (
  • Kelp seaweed: It is rich in many minerals, such as iodine, selenium, calcium , magnesium and potassium . (
  • The study also found that selenium status is suboptimal in many Europeans. (
  • Short-term oral exposure to high concentrations of selenium may cause nausea, vomiting, and diarrhea. (
  • Concentrations of selenium in whole blood, plasma, and leucocytes were determined in 16 patients with coeliac disease confirmed by biopsy and 32 controls. (
  • The concentrations of selenium were significantly lower in the leucocytes, blood, and plasma of patients compared with controls, probably indicating a decrease in the body content of selenium. (
  • As a protective role for selenium against cancer has been postulated, the importance of this unexpected observation of lowered tissue concentrations of selenium requires further investigation. (
  • The most toxic compound of selenium following inhalation is hydrogen selenide. (
  • More than 400 mcg per day of supplemental selenium may be toxic. (
  • Furthermore, selenium reduces the toxic effects of some xenobiotics, especially heavy metals, converting them to stable, less toxic forms. (
  • See also the Selenium page provided by ATSDR (Agency for Toxic Substances & Disease Registry). (
  • Selenium is toxic, and as Americans, we tend to really overdo it. (
  • Until very recently, selenium was considered a toxic element that was not necessary to human health. (
  • Yet the company's report concluded that it would be safe to allow selenium - a metal byproduct of mining that is toxic to fish and birds - to remain in area creeks at higher levels than are now permitted under regulatory guidelines. (
  • Selenium is a pollutant at 200 of the 1,294 locations designated by the federal government as toxic Superfund sites. (
  • California's San Joaquin Valley has some of the highest natural levels of selenium (a chemical element that is highly toxic in large doses) found anywhere. (
  • Selenium is a trace element that is essential in small amounts, but like all essential elements, selenium can be toxic at high levels. (
  • Consequently the simple inclusion of selenium in a basal formulation may lead to toxic effects. (
  • Selenium, in superior doses or by accumulation, may be toxic. (
  • Second, however important as a micronutrient-you need at least 55 micrograms per day (usually from meat, eggs, or nuts)-selenium becomes toxic pretty quickly. (
  • Youngevity CEO, Steve Wallach, said, "My father, Dr. Wallach, has been lecturing on the health benefits of selenium for over 30 years and continues to lecture almost daily, traveling 300 days a year in order to get the message out to the world. (
  • Today, Dr. Wallach is renowned for his groundbreaking research on the health benefits of selenium and other minerals. (
  • Selenium is a trace mineral needed in small amounts for good health, but exposure to much higher levels can result in neurological effects and brittle hair and deformed nails. (
  • Because of this widespread availability, we believe that selenium is a mineral you'll have little trouble getting from our recipes. (
  • Selenium is an essential trace mineral that supports many bodily processes. (
  • However, there is no consistent clinical evidence to suggest that the mineral lowers the risk of cardiovascular disease, especially in healthy people who already get selenium from food. (
  • Selenium is an essential trace mineral that is important for many bodily processes, including cognitive function, a healthy immune system, and fertility in both men and women. (
  • Selenium is a mineral that plays a role in many bodily functions. (
  • Selenium is an essential trace mineral that assists with cognitive function and fertility. (
  • Selenium is also found in water and so also occurs in varying quantities in seafood, but despite its relatively common appearance in foods, many people are lacking this important mineral. (
  • Selenium has also been linked to a reduced risk of bladder cancer, although one of the most well-known studies regarding cancer and selenium was a 1996 study by the late Larry Clark, Ph.D., of the University of Arizona, which linked the mineral to an overall lower incidence of cancer risk of death. (
  • A minimum dietary level of paints, anti-dandruff shampoos, vitamin and mineral selenium is required for good health. (
  • Selenium is a mineral. (
  • Many multivitamin and mineral formulas contain selenium. (
  • Selenium is a trace essential mineral with anti-oxidant properties. (
  • Selenium is a trace mineral that our bodies use to produce glutathione peroxidase . (
  • Symptoms of selenium toxicity are more severe than simply consuming too much of the mineral. (
  • Selenium is a trace mineral that is essential for cellular function in the body. (
  • Selenium is an essential trace mineral that serves many functions in human physiology, including the synthesis of antioxidants (natural substances that neutralize free radical damage), and thyroid and immune function. (
  • The ease of application of these products is the most exciting aspect, particularly the liquid organic selenium option, which enables water application of this vital mineral," says Ms Parker. (
  • Selenium is an essential mineral that we need in small amounts, which means we must get it through our diets. (
  • citation needed] Increased risk for developing various diseases has also been noted, even when certain individuals lack optimal amounts of selenium, but not enough to be classified as deficient. (
  • Animal studies have shown that very high amounts of selenium can affect sperm production and the female reproductive cycle. (
  • Most of our food groups at WHFoods provide valuable amounts of selenium. (
  • The body typically stores some selenium in human tissue, mostly in skeletal muscles, after getting it from foods containing trace amounts. (
  • Selenium requirements in plants differ by species, with some plants requiring relatively large amounts and others apparently requiring none. (
  • Brand names for selenium sulfide include Head & Shoulders, Selsun Blue , SelRx, and Selsun Rx. (
  • Selenium is required for the proper activity of a group of enzymes called glutathione peroxidases. (
  • Of the eight known glutathione peroxidase enzymes, five of them require selenium. (
  • Selenium is incorporated into glutathione and thioredoxin reductase(s), glutathione peroxidase(s), and selenoprotein P as the amino acid selenocysteine. (
  • The selenium-dependent glutathione peroxidase (GSHPx) family has at least four members that protect against the deleterious effects of peroxides and hydroperoxides. (
  • A selenium-containing enzyme is responsible for transforming a less active thyroid hormone called T4 into the more active T3. (
  • Researchers have been able to induce problems with the thyroid gland in just two months of a low-selenium diet. (
  • Selenium is also involved in converting thyroid hormone, converting methionine to cysteine, and producing the immunoglobulin antibodies IgM and IgG in the immune system and in the colostrum. (
  • Selenium is essential for the proper synthesis, activation, and metabolism of thyroid hormones. (
  • Selenium is a nutrient that plays a key role in maintaining thyroid hormone metabolism and DNA synthesis and protecting the body from oxidative damage and infection. (
  • Selenium also has an important role in maintaining healthy thyroid function. (
  • Selenium has an important role in producing and metabolizing thyroid hormone. (
  • There is some evidence that women with higher selenium levels have fewer thyroid problems, but this has not been proven for men, and other studies have produced mixed results. (
  • Selenium, therefore, plays an important role in preventing chronic diseases and is also important for thyroid and immune system function. (
  • Research shows that taking 200 mcg of selenium daily along with thyroid hormone might decrease antibodies in the body that contribute to this condition. (
  • With Lindens®, you can expect Selenium contributes to healthy hair, nails, immune and thyroid function. (
  • Another important benefit of selenium is the role it plays in supporting thyroid function . (
  • But too much selenium can decrease thyroid hormone production and cause hair loss, skin lesions and brittle fingernails. (
  • In the body, selenium lives mainly in our muscles, 5 but the thyroid gland has the highest concentration of selenium so it's important to get enough selenium from your diet for a healthy thyroid function. (
  • A selenium supplement might also be useful for people with thyroid eye disease, according to the British Thyroid Foundation charity. (
  • Other research found there to be no connection, and some even indicated high selenium levels were associated with an increased heart disease risk. (
  • In 2015, research published in the International Journal of Cancer revealed that higher selenium levels are linked to a lower risk of colorectal cancer, particularly in women. (
  • And those who started the study with the highest selenium levels -- 122 micrograms or higher -- saw a nearly three-fold jump in diabetes risk compared to those taking a placebo. (
  • As of now, selenium toxicity is diagnosed based upon the presence of features of selenosis in humans, since there are no accurate biochemical or preclinical parameters. (
  • Selenium toxicity in animals was detected by the occurrence of neurological and muscular symptoms in cattle during the 1930's. (
  • In animals, selenium toxicity has also been associated with abnormal fetal development in cattle, swine and sheep, but with infertility and a higher proportion of runt offspring and fetal deaths. (
  • The symptoms of chronic selenium toxicity or selenosis first appear as a garlicky odor in the breath, and a metallic taste in the mouth. (
  • The cancer reductions were so significant that the blinded phase of the trial was stopped early, and no cases of selenium toxicity occurred. (
  • Earlier, selenium was recognised only for its toxicity, but its importance in human body cannot be ignored. (
  • Fortunately, large doses of selenium causing acute toxicity and death are uncommon in the horse. (
  • Selenium toxicity is more often a chronic condition. (
  • The chronic signs of selenium toxicity are characterized by hair loss of the mane and tail, cracking of the hooves, and often signs of lameness, excess salivation, and respiratory failure. (
  • Nursing mothers should note that human milk is much richer in selenium than cow's milk. (
  • The review article by Drs. Das and Kaplan nicely summarizes most of the data available on the use of PC-SPES, selenium, and vitamin E by prostate cancer patients. (
  • This article provides physicians with a useful tool for discussing with theirpatients what is known about the use of PC-SPES, vitamin E, and selenium. (
  • In concert with vitamin E, selenium is also involved in the protection of cell membranes against oxidative damage (see Chapter 6 , Chapter 9 , and Chapter 17 ). (
  • Currently the SELECT trial (the Selenium and Vitamin E Cancer Prevention Trial) is in progress. (
  • Vitamin C, selenium and zinc help in the proper functioning of the immune system. (
  • Young, fast growing animals nursing from dams fed a diet low in selenium and vitamin E are commonly affected. (
  • An overdose of selenium can be fatal-just last year, 21 polo ponies slumped over dead before a match in Florida after receiving vitamin injections with too much selenium-but scientists have re-evaluated the evidence for it causing madness. (
  • No one's ever been able to demonstrate any benefit for taking high doses of selenium or vitamin E, so why do it? (
  • The new study is based on data gathered during the Selenium and Vitamin E Cancer Prevention Trial (SELECT), which was funded by the U.S. National Cancer Institute. (
  • The trial was designed to last 12 years, but was stopped early in 2008 after finding no protective benefit for selenium and an increased risk of prostate cancer among men taking vitamin E. (
  • During the trial, men took 200 micrograms (mcg) of selenium and 400 IU of vitamin E daily, either separately or in combination. (
  • Among men with low selenium levels, taking vitamin E increased their total risk of prostate cancer by 63 percent and their risk of aggressive cancer by 111 percent. (
  • If selenium is oxidized, it is present as the anion selenate (SeO42-) that can be removed from solution with an anion exchange resin. (
  • This is a major concern for NZ animal production, particularly in the dairy sector where selenium options have until now been limited to sodium selenite/selenate and selenium yeast. (
  • Zoomec Plus Selenium may be available in the countries listed below. (
  • What is the most important information I should know about selenium sulfide topical? (
  • Selenium sulfide topical (for the skin) is used to treat dandruff, seborrhea, and tinea versicolor (a fungus that discolors the skin). (
  • Selenium sulfide topical may also be used for purposes not listed in this medication guide. (
  • What should I discuss with my healthcare provider before using selenium sulfide topical? (
  • FDA pregnancy category C. It is not known whether selenium sulfide topical will harm an unborn baby. (
  • It is not known whether selenium sulfide topical passes into breast milk or if it could harm a nursing baby. (
  • Selenium sulfide topical should not be used on a child younger than 2 years old without a doctor's advice. (
  • How should I use selenium sulfide topical? (
  • Selenium sulfide topical shampoo is generally not for daily use. (
  • Call your doctor if your symptoms do not improve, or if they get worse while using selenium sulfide topical. (
  • An overdose of selenium sulfide topical is not expected to be dangerous. (
  • What should I avoid while using selenium sulfide topical? (
  • What other drugs will affect selenium sulfide topical? (
  • Avoid using other topical medications at the same time you apply selenium sulfide topical, unless your doctor approves. (
  • Other skin medications may affect the absorption or effectiveness of selenium sulfide topical. (
  • Your pharmacist can provide more information about selenium sulfide topical. (
  • Copper, manganese, selenium and zinc in wild-growing edible mushrooms from the eastern territory of "green lungs of Poland": nutritional and toxicological implications - Miro ńczuk-Chodakowska I, Socha K, Zujko ME, Terlikowska KM, Borawska MH, Witkowska AM. (
  • Almost all the World's Healthiest Foods contain at least some selenium. (
  • The following chart shows the World's Healthiest Foods that are either an excellent, very good, or good source of selenium. (
  • Learn the benefits, how much to take, drug interactions and which foods are full of selenium. (
  • Selenium is found in many foods such as seafood, lean meats, grains, eggs and garlic. (
  • An organic form of selenium, selenomethionine, is found in foods. (
  • Much of the selenium in foods is lost during processing. (
  • Foods that are high in selenium contain the element in an organic form, selenomethionine. (
  • The selenium content of plant foods varies from one country to another and also shows regional variation. (
  • Using his twenty-year experience, the author discusses the effects of selenium on fish and bird populations and presents guidelines for identifying sources of pollution, interpreting selenium concentrations, assessing hazardous conditions, setting water quality criteria and ecosystem loading limits (TMDLs). (
  • Adverse effects of selenium (Se) on fish and waterfowl in wetlands receiving agricultural drainage occurred in the 1980s in the San Joaquin Valley of California. (
  • In the absence of placebo-controlled trials to evaluate the long-term effects of selenium on type 2 diabetes risk, the investigators examined data from the Nutritional Prevention of Cancer Trial. (
  • The average content of selenium in products based on popular gluten-free cereals was 2.8 μg/100 g and in products based on oat, amaranth, teff, and quinoa was 10.8 μg/100 g. (
  • Body content of selenium in coeliac disease. (
  • Hinks L J , Inwards K D , Lloyd B , Clayton B E . Body content of selenium in coeliac disease. (
  • Severe overdose of selenium can lead to death. (
  • Occupational inhalation exposure to selenium vapors may cause dizziness, fatigue, irritation of mucous membranes, and respiratory effects. (
  • Exposure to selenium hexafluoride can cause irritation of the respiratory airway, skin and eyes. (
  • There is no information on whether exposure to selenium hexafluoride may affect the reproductive system in humans or in animals. (
  • We do not know if exposure to selenium hexafluoride will result in birth defects or other developmental effects in people. (
  • How can families reduce the risk of exposure to selenium hexaflouride? (
  • It was Thressa Stadtman who identified the biological importance of selenium in the synthesis of the redox enzyme glycine reductase. (
  • The generally higher levels for males are related to the importance of selenium in producing vigorous sperm. (
  • In the study of 1,300 older people, the occurrence of cancer among those who took 200 micrograms of selenium daily for about seven years was reduced by 42 percent compared to those given a placebo. (
  • One study of more than 1,200 Americans, for example, found that those who took 200 micrograms of selenium daily for an average of nearly eight years had a higher risk of developing type 2 diabetes compared to those taking a placebo. (
  • Enrollees were assigned randomly to take a tablet containing 200 micrograms of selenium daily or a placebo. (
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  • In a randomized, placebo-controlled, double-blind trial, daily doses of selenium substantially increased serum levels of the metal and prevented increases in HIV viral load, found Barry Hurwitz, Ph.D., of the University of Miami. (
  • Bleys J, Navas-Acien A, Guallar E. Serum selenium levels and all-cause, cancer, and cardiovascular mortality among US adults. (
  • It is worth noting that the basal formulations, DMEM/Ham's Nutrient Mixture F-12 (50:50) and Iscove's Modified Dulbecco's Medium (IMDM) are often supplemented with selenium as part of their modifications into proprietary serum-free or protein-free commercial media useful for recombinant heterologous protein, including monoclonal antibody (Mab), manufacturing. (
  • Selenium status in horses can be measured using serum, plasma, or whole blood selenium levels. (
  • Selenium has selenium in rocks is combined with sulfide minerals been found in at least 508 of the 1,623 current or or with silver, copper, lead, and nickel minerals. (
  • People may be exposed to low levels of selenium daily through food and water. (
  • The general population is exposed to very low levels of selenium in air, food, and water. (
  • People working in or living near industries where selenium is produced, processed, or converted into commercial products may be exposed to higher levels of selenium in the air. (
  • People living in the vicinity of hazardous waste sites or coal burning plants may also be exposed to higher levels of selenium. (
  • In fact, studies in humans suggest that lower-than-normal selenium levels in the diet might increase the risk of cancer. (
  • Scientists have also suggested that selenium levels during pregnancy may be a factor in the development of childhood asthma. (
  • 3 Why is it so important to be sure your body has optimal selenium levels? (
  • In the U.S., the Eastern Coastal Plain and the Pacific Northwest have the lowest selenium levels. (
  • Some research shows that taking a 100-200 mcg of a specific selenium supplement (SelenoPrecise, Pharma Nord, Denmark) daily for 6 months can modestly reduce cholesterol levels. (
  • Many people in this study had low levels of selenium in their body before the start of the study. (
  • Are Selenium Levels Linked to Diabetes? (
  • Americans with diabetes have high levels of selenium in their bodies, prompting some health experts to suspect that it could contribute to development of the disease. (
  • The research team, led by Johns Hopkins University epidemiologists, examined the diabetes rate and selenium levels of 917 people over the age of 40 who participated in a national health study conducted by the U.S. Centers for Disease Control and Prevention in 2003 and 2004. (
  • Since then, average selenium levels in the country have increased 9 percent. (
  • One particular epidemiological study published in May 2004 in the Journal of National Cancer Institute revealed that men with high blood levels of selenium were about half as likely to develop advanced prostate cancer as the men with lower blood selenium. (
  • A recent study concludes that consuming higher levels of dietary selenium shows an association with a reduced risk of developing osteoporosis. (
  • A team led by Dr Saverio Stranges at the University's Warwick Medical School has found high levels of selenium are associated with increased cholesterol, which can cause heart disease. (
  • In a paper recently published in the Journal of Nutrition , the research team examined the association of plasma selenium concentrations (levels of selenium in the blood) with blood lipids (fats in the blood). (
  • The report concluded that selenium should be allowed in higher levels in creeks than is now permitted under regulations. (
  • Bees that have been brought from somewhere else probably couldn't have evolved mechanisms to deal with the high levels of selenium, so maybe the solution (as is most often the case) is to stick with native species. (
  • As a result, the "non-responders" had selenium levels and HIV responses closer to the placebo group, Dr. Hurwitz and colleagues said. (
  • Selenium "non-responders" did not differ from the placebo group in HIV levels and CD4 counts. (
  • Some research found people with lower selenium levels to have a higher risk of heart disease. (
  • While supplementing selenium is not recommended for preventing heart disease and lowering cholesterol levels, there are many other steps you can take to reduce your risk for those hazards. (
  • Xun P, Liu K, Morris JS, Daviglus ML, He K. Longitudinal association between toenail selenium levels and measures of subclinical atherosclerosis: the CARDIA trace element study. (
  • Health benefits may be linked to selenium but according to a team led by Dr Saverio Stranges at Warwick University, the balance can be tipped and high levels of selenium in the diet are associated with increased cholesterol. (
  • The scientists reached this conclusion after examining the relationship between plasma selenium concentrations (levels of selenium in the blood) with blood lipids (fats in the blood). (
  • If you are concerned about selenium levels, consult your local veterinarian for additional information on testing. (
  • It turns out that existing selenium levels did make a difference. (
  • Low doses of selenium are needed to maintain good health. (
  • Selenium, when taken in appropriate doses, is not contraindicated in pregnancy. (
  • High doses of selenium have also been linked to skin cancer , he added. (
  • In a research review published in The Lancet , Rayman concludes that most Americans get enough selenium in their diets. (
  • Studies suggest that many people in certain developed countries, including New Zealand, Belgium, and Scandinavia, do not get enough selenium in their diets. (
  • In general, absorption of dietary selenium is lower in ruminants than in non-ruminants, and is lower from forages than from grain. (
  • About 60% of dietary selenium is absorbed as food passes through the intestines. (
  • The selenium content of normal adult humans can vary widely. (
  • The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the EPA have not classified selenium hexafluoride as to its carcinogenicity to humans. (
  • Most of the selenium found in humans and animals is organic selenomethionine or selenocysteine. (
  • Unlike plants, most animals - including humans - require selenium for the appropriate functioning of a number of selenium-dependent enzymes known as selenoproteins. (
  • Selenium has been used since the 1960s in dandruff shampoos and topical medications for such skin disorders as folliculitis ("hot tub" syndrome) and tinea versicolor, a mild infection of the skin caused by the yeast-like fungus Pityrosporum orbiculare . (
  • Those in the selenium group received 200 mcg/day of the metal, in a high-yield yeast formulation. (
  • The recommended daily allowance (RDA) of selenium is 55 ug (micrograms). (
  • The government's recommended daily allowance for selenium is 55 micrograms for adults aged 19 and over. (
  • In 1989, selenium was reclassified as an essential micronutrient in a balanced human diet when the National Research Council established the first recommended daily allowance (RDA) for it. (
  • Selenium disulfide has a composition that approximates to SeS 2 and is sometimes called selenium sulfide. (