Sebum
Sebaceous Glands
Acne Vulgaris
Dermatitis, Seborrheic
Squalene
Isotretinoin
Encyclopedias as Topic
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The role of specific retinoid receptors in sebocyte growth and differentiation in culture. (1/82)
Retinoic acid derivatives (retinoids) exert their pleiotropic effects on cell development through specific nuclear receptors, the retinoic acid receptors and retinoid X receptors. Despite recent progress in understanding the cellular and molecular mechanisms of retinoid activity, it is unknown which of the retinoid receptor pathways are involved in the specific processes of sebocyte growth and development. In this study, we investigated the roles of specific retinoid receptors in sebocyte growth and differentiation, by testing the effects of selective retinoic acid receptor and retinoid X receptor ligands at concentrations between 10-10 M and 10-6 M in a primary rat preputial cell monolayer culture system. Cell growth was determined by number of cells and colonies, and cell differentiation by analysis of lipid-forming colonies. All-trans retinoic acid and selective retinoic acid receptor agonists (CD271 = adapalene, an RAR-beta,gamma agonist; CD2043 = retinoic acid receptor pan-agonist; and CD336 = Am580, an RAR-alpha agonist) caused significant decreases in numbers of cells, colonies, and lipid-forming colonies, but with an exception at high doses of all-trans retinoic acid (10-6 M), with which only a small number of colonies grew but they became twice as differentiated as controls (42.2 +/- 4.0% vs 22.6 +/- 2.7%, mean +/- SEM, lipid-forming colonies, p < 0.01). Furthermore, the RAR-beta,gamma antagonist CD2665 antagonized the suppressive effects of all-trans retinoic acid, adapalene, and CD2043 on both cell growth and differentiation. In contrast, the retinoid X receptor agonist CD2809 increased cell growth slightly and lipid-forming colonies dramatically in a clear dose-related manner to a maximum of 73.7% +/- 6.7% at 10-6 M (p < 0. 001). Our data suggest that retinoic acid receptors and retinoid X receptors differ in their roles in sebocyte growth and differentiation: (i) retinoic acid receptors, especially the beta and/or gamma subtypes, mediate both the antiproliferative and antidifferentiative effects of retinoids; (ii) retinoid X receptors mediate prominent differentiative and weak proliferative effects; (iii) the antiproliferative and antidifferentiative effects of all-trans retinoic acid are probably mediated by retinoic acid receptors, whereas its differentiative effect at high dose may be mediated by retinoid X receptors via all-trans retinoic acid metabolism to 9-cis retinoic acid, the natural ligand of retinoid X receptors. (+info)Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. (2/82)
The secretion and the blood levels of the adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) decrease profoundly with age, and the question is posed whether administration of the steroid to compensate for the decline counteracts defects associated with aging. The commercial availability of DHEA outside the regular pharmaceutical-medical network in the United States creates a real public health problem that may be resolved only by appropriate long-term clinical trials in elderly men and women. Two hundred and eighty healthy individuals (women and men 60-79 years old) were given DHEA, 50 mg, or placebo, orally, daily for a year in a double-blind, placebo-controlled study. No potentially harmful accumulation of DHEAS and active steroids was recorded. Besides the reestablishment of a "young" concentration of DHEAS, a small increase of testosterone and estradiol was noted, particularly in women, and may be involved in the significantly demonstrated physiological-clinical manifestations here reported. Bone turnover improved selectively in women >70 years old, as assessed by the dual-energy x-ray absorptiometry (DEXA) technique and the decrease of osteoclastic activity. A significant increase in most libido parameters was also found in these older women. Improvement of the skin status was observed, particularly in women, in terms of hydration, epidermal thickness, sebum production, and pigmentation. A number of biological indices confirmed the lack of harmful consequences of this 50 mg/day DHEA administration over one year, also indicating that this kind of replacement therapy normalized some effects of aging, but does not create "supermen/women" (doping). (+info)13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors. (3/82)
Despite its potent biologic effect on human sebocytes, 13-cis retinoic acid exhibits low binding affinity for cellular retinoic acid binding proteins and nuclear retinoid receptors. Hence, 13-cis retinoic acid may represent a pro-drug possibly acting through all-trans isomerization. In this study, marked isomerization of 13-cis retinoic acid has been confirmed in cultured SZ95 sebocytes showing 2- to 15-fold higher levels of all-trans retinoic acid at 12-72 h, as measured by high performance liquid chromatography. In contrast, only low amounts of all-trans retinoic acid were converted intracellularly to its 13-cis isoform. 9-cis retinoic acid was not detected after either 13-cis retinoic acid or all-trans retinoic acid treatment. The rapid isomerization of 13-cis retinoic acid to high levels of all-trans retinoic acid was a sebocyte-specific event, as no significant isomerization of 13-cis retinoic acid to all-trans retinoic acid occurred in HaCaT keratinocytes. De novo mRNA expression of cytochrome P450 1A1, a major xenobiotic metabolizing enzyme, in SZ95 sebocytes was induced by all-trans retinoic acid, but not by 13-cis retinoic acid. In addition, mRNA levels of cellular retinoic acid-binding protein II, which is supposed to regulate the concentration of intracellular all-trans retinoic acid, rapidly increased under all-trans retinoic acid treatment (30 min-6 h), whereas the 13-cis retinoic acid effect was markedly weaker and delayed. Both 13-cis retinoic acid and all-trans retinoic acid suppressed mRNA expression of cytochrome P450 1A2. In parallel experiments, 13-cis retinoic acid significantly reduced SZ95 sebocyte proliferation at 10-7 M, show- ing 30-40% inhibition after 9 d. All-trans retinoic acid and 9-cis retinoic acid exhibited similar anti-proliferative effects. AGN 193109, a pan-antagonist of the retinoic acid receptors, antagonized the anti-proliferative activity of all retinoic acid isomers tested in a concentration-dependent manner with complete abolishment at ratios of 1:10 13-cis retinoic acid and 1:1 all-trans retinoic acid. Coincubation of SZ95 sebocytes with 13-cis retinoic acid and AGN 193109 did not alter the intracellular concentration of 13-cis retinoic acid and its isomerization profile. In contrast, the retinoid X receptor antagonist CD 3507 did not affect the inhibition of SZ95 sebocyte proliferation induced by retinoic acids. Our findings indicate: (i) a selective 13-cis retinoic acid isomerization to all-trans retinoic acid in the intracellular compartment of SZ95 sebocytes; (ii) a reduced all-trans retinoic acid inactivation process after 13-cis retinoic acid treatment as compared with treatment with all-trans retinoic acid; and (iii) a retinoic acid receptor-mediated inhibition of SZ95 sebocyte proliferation. These data explain the sebocyte-specific activity of 13-cis retinoic acid and support a pro-drug/drug relation between 13-cis retinoic acid and all-trans retinoic acid. (+info)The melanocortin 5 receptor is expressed in human sebaceous glands and rat preputial cells. (4/82)
Melanocortins regulate pigmentation, adrenal hormone secretion, immune functions, lipid metabolism, and feeding behaviors in rodents. These peptides include adrenocorticotrophic hormone, melanocyte stimulating hormone, beta-lipotrophin, and the endorphins. Lipid metabolism in sebaceous glands and preputial glands of rodents is regulated by alpha-melanocyte stimulating hormone, the major agonist for melanocortin receptors. Five melanocortin receptor subtypes have been identified that differ in their tissue localization and affinities for melanocortin ligands. Targeted disruption of the melanocortin 5 receptor in transgenic mice results in widespread dysfunction of exocrine glands, including a marked decrease in sebum production. A role for melanocortins in the modulation of human sebum production has not been established. The goal of this study is to determine which melanocortin receptors are expressed in human sebaceous glands. Messenger RNA was isolated from human sebaceous glands and the reverse transcriptase polymerase chain reaction was performed using primers specific for each of the melanocortin receptor subtypes. Transcripts were detected for the melanocortin 5 receptor. A polyclonal chicken antihuman antibody to the melanocortin 5 receptor localized to sebaceous glands, eccrine glands, hair follicles, and epidermis in human skin, rat skin, cultured human sebocytes, and rat preputial cells. Presence of the melanocortin 5 receptor protein in human sebaceous glands and rat preputial glands was further verified by Western blotting. These data support further investigation of the role of melanocortins in the regulation of human sebum production and support the use of the rat preputial system as an experimental model in sebaceous gland physiology. (+info)Attenuated total reflection-Fourier transform infrared spectroscopy as a possible method to investigate biophysical parameters of stratum corneum in vivo. (5/82)
We investigated the use of attenuated total reflection-Fourier transform infrared spectroscopy as a method to study differences in the molecular components of human stratum corneum in vivo. These variations as a function of the anatomic site and of the depth into its layered structure are important to understand the biology and physiology of the tissue. In this preliminary study we have investigated spectroscopic changes in 18 healthy individuals. Total reflection-Fourier transform infrared spectroscopy represents a potentially powerful tool to study biophysical properties of surfaces. We observed that, in vivo, biophysical parameters of the stratum corneum (such as hydration, lipid composition, and conformation of the aliphatic chains) are indeed dependent on the anatomic site. As in total reflection-Fourier transform infrared spectroscopy experiments the penetration depth of the evanescent field into the stratum corneum is comparable with the thickness of a layer of corneocytes, this technique can be used to follow the distribution of lipids, water, and proteins as a function of depth into the tissue. We found that, in vivo, these molecular components are non-uniformly distributed, in agreement with the presence of water and lipid reservoirs as observed with ex vivo ultrastructural investigations. Composition and conformational order of lipids are also a function of depth into the stratum corneum. Finally we compared the in vivo superficial hydration measured using the infrared absorption of the OH stretch of water, with the hydration measured using the Skicon hygrometer. Our results indicate that total reflection-Fourier transform infrared spectroscopy might be useful to measure important chemical and biophysical parameters of stratum corneum in vivo. (+info)The influence of two azones and sebaceous lipids on the lateral organization of lipids isolated from human stratum corneum. (6/82)
The main problem with topical application of compounds to administer drugs to and regulate drug levels in a human body, is the barrier formed by the intercellular lipid matrix of the stratum corneum (SC). In a search for possibilities to overcome this barrier function, a good understanding of the organization and phase behavior of these lipids is required. SC lipid model studies especially provide a wealth of information with respect to the lipid organization and the importance of certain subclasses of lipids for the structure. Previously, we have shown that electron diffraction (ED) provides detailed information on the lateral lipid packing in both intact SC (G.S.K. Pilgram et al., J. Invest. Dermatol. 113 (1999) 403) and SC lipid models (G.S.K. Pilgram et al., J. Lipid Res. 39 (1998) 1669). In the present study, we used ED to examine the influence of two azones and sebaceous lipids on the lateral phase behavior of lipids isolated from human SC. We established that human SC lipids are arranged in an orthorhombic packing pattern. Upon mixing with the two enhancers the orthorhombic packing pattern was still observed; however, an additional fluid phase became more apparent. In mixtures with sebaceous lipids, the presence of the hexagonal lattice increased. These findings provide a basis for the mechanism by which these enhancers and sebaceous lipids interact with human SC lipids. (+info)Sebocytes are the key regulators of androgen homeostasis in human skin. (7/82)
The mRNA expression patterns of the androgen receptor and the androgen metabolizing enzymes 3beta-hydroxysteroid dehydrogenase/Delta(5-4)-isomerase, 17beta-hydroxysteroid dehydrogenase, 5alpha-reductase, and 3alpha-hydroxysteroid dehydrogenase were investigated in three different cell populations originating from human skin, SZ95 sebocytes, HaCaT keratinocytes, and MeWo melanoma cells, by means of reverse transcription polymerase chain reaction. Restriction analysis of cDNA fragments was performed to identify isozymes of 3beta-hydroxysteroid dehydrogenase/Delta(5-4)-isomerase and 3alpha-hydroxysteroid dehydrogenase. In addition, 3H-dihydroepiandrosterone and 3H-testosterone were used as substrates to determine the metabolic activity of these enzymes in SZ95 sebocytes, primary sebocyte cultures, and HaCaT keratinocytes. Furthermore, the effects of the selective 5alpha-reductase type 1 and 2 inhibitors, 4,7beta-dimethyl-4-aza-5alpha-cholestan-3-one and dihydrofinasteride, respectively, and of the 3beta-hydroxysteroid dehydrogenase/Delta(5-4)-isomerase inhibitor cyproterone acetate on androgen metabolism were investigated. Androgen receptor mRNA was detected in SZ95 sebocytes and HaCaT keratinocytes but not in MeWo melanoma cells, whereas 3beta-hydroxysteroid dehydrogenase/Delta(5-4)-isomerase isotype 1 mRNA and metabolic activity were only found in SZ95 sebocytes. The enzyme activity could be inhibited by cyproterone acetate. Type 2 17beta-hydroxysteroid dehydrogenase, type 1 5alpha-reductase, and 3alpha-hydroxysteroid dehydrogenase mRNA were expressed in all three cell populations tested, whereas type 3 17beta-hydroxysteroid dehydrogenase mRNA could only be detected in SZ95 sebocytes. The major metabolic steps of testosterone in SZ95 sebocytes, primary sebocyte cultures, and HaCaT keratinocytes were its conversion to androstenedione by 17beta-hydroxysteroid dehydrogenase and further to 5alpha-androstanedione by 5alpha-reductase. The type 1 5alpha-reductase selective inhibitor 4,7beta-dimethyl-4-aza-5alpha-cholestan-3-one, but not the type 2 selective inhibitor dihydrofinasteride, inhibited 5alpha-reductase at low concentrations in SZ95 sebocytes and HaCaT keratinocytes. 5alpha-androstanedione was degraded to androsterone by 3alpha-hydroxysteroid dehydrogenase, which exhibited a stronger activity in HaCaT keratinocytes than in SZ95 sebocytes and in primary sebocyte cultures. Lower levels of 5alpha-dihydrotestosterone and 5alpha-androstanediol were also detected in all cells tested. Our investigations show that specific enzyme expression and activity in cultured sebocytes and keratinocytes seem to allocate different duties to these cells in vitro. Sebocytes are able to synthesize testosterone from adrenal precursors and to inactivate it in order to maintain androgen homeostasis, whereas keratinocytes are responsible for androgen degradation. (+info)Why do we have apocrine and sebaceous glands? (8/82)
The secretions of sebaceous and apocrine glands fulfil an important thermoregulatory role in cold-stressed and heat-stressed hunter-gatherers. In hot conditions the secretions emulsify eccrine sweat and thus encourage the formation of a sweat sheet and discourage the formation and loss of sweat drops from the skin. In colder conditions sebum changes its nature and repels rain from skin and hair. (+info)Sebum is an oily, waxy substance that is produced by the sebaceous glands in the skin of mammals. It is composed mainly of triglycerides, wax esters, squalene, and free fatty acids, as well as smaller amounts of metabolites and other substances. Sebum plays an important role in the maintenance of the skin's barrier function and in the regulation of its moisture levels. It also has antimicrobial properties that help to protect the skin from infection. Excessive sebum production can contribute to the development of acne and other skin conditions.
Sebaceous glands are microscopic, exocrine glands that are found in the dermis of mammalian skin. They are attached to hair follicles and produce an oily substance called sebum, which is composed of triglycerides, wax esters, squalene, and metabolites of fat-producing cells (fatty acids, cholesterol). Sebum is released through a duct onto the surface of the skin, where it forms a protective barrier that helps to prevent water loss, keeps the skin and hair moisturized, and has antibacterial properties.
Sebaceous glands are distributed throughout the body, but they are most numerous on the face, scalp, and upper trunk. They can also be found in other areas of the body such as the eyelids (where they are known as meibomian glands), the external ear canal, and the genital area.
Abnormalities in sebaceous gland function can lead to various skin conditions, including acne, seborrheic dermatitis, and certain types of skin cancer.
Acne vulgaris is a common skin condition characterized by the formation of various types of blemishes on the skin, such as blackheads, whiteheads, papules, pustules, and cysts or nodules. These lesions typically appear on areas of the body that have a high concentration of sebaceous glands, including the face, neck, chest, back, and shoulders.
Acne vulgaris occurs when hair follicles become clogged with dead skin cells and excess oil (sebum) produced by the sebaceous glands. This blockage provides an ideal environment for bacteria, particularly Propionibacterium acnes, to multiply, leading to inflammation and infection. The severity of acne vulgaris can range from mild with only a few scattered comedones (blackheads or whiteheads) to severe cystic acne, which can cause significant scarring and emotional distress.
The exact causes of acne vulgaris are not fully understood, but several factors contribute to its development, including:
1. Hormonal changes during puberty, menstruation, pregnancy, or due to conditions like polycystic ovary syndrome (PCOS)
2. Genetic predisposition
3. Use of certain medications, such as corticosteroids and lithium
4. Excessive production of sebum due to overactive sebaceous glands
5. Accumulation of dead skin cells that clog pores
6. Bacterial infection (particularly Propionibacterium acnes)
7. Inflammation caused by the body's immune response to bacterial infection and clogged pores
Treatment for acne vulgaris depends on its severity and can include over-the-counter or prescription topical treatments, oral medications, chemical peels, light therapies, or even hormonal therapies in some cases. It is essential to seek professional medical advice from a dermatologist or healthcare provider to determine the most appropriate treatment plan for individual needs.
Seborrheic dermatitis is a common, inflammatory skin condition that mainly affects the scalp, face, and upper part of the body. It causes skin irritation, flaking, and redness, often in areas where the skin is oily or greasy. The exact cause of seborrheic dermatitis is not fully understood, but it appears to be related to a combination of genetic, environmental, and microbial factors.
The symptoms of seborrheic dermatitis can vary in severity and may include:
* Greasy or flaky scales on the scalp, eyebrows, eyelashes, ears, or beard
* Redness and inflammation of the skin
* Itching, burning, or stinging sensations
* Yellow or white crusty patches on the scalp or other affected areas
* Hair loss (in severe cases)
Seborrheic dermatitis is a chronic condition that tends to flare up and then subside over time. While there is no cure for seborrheic dermatitis, various treatments can help manage the symptoms and prevent complications. These may include medicated shampoos, topical creams or ointments, and lifestyle changes such as stress reduction and avoiding triggers that worsen symptoms.
It is important to note that seborrheic dermatitis should not be confused with other skin conditions, such as psoriasis or eczema, which may have similar symptoms. A healthcare professional can provide a proper diagnosis and recommend appropriate treatment options based on the individual's specific needs.
Squalene is a organic compound that is a polyunsaturated triterpene. It is a natural component of human skin surface lipids and sebum, where it plays a role in maintaining the integrity and permeability barrier of the stratum corneum. Squalene is also found in various plant and animal tissues, including olive oil, wheat germ oil, and shark liver oil.
In the body, squalene is an intermediate in the biosynthesis of cholesterol and other sterols. It is produced in the liver and transported to other tissues via low-density lipoproteins (LDLs). Squalene has been studied for its potential health benefits due to its antioxidant properties, as well as its ability to modulate immune function and reduce the risk of certain types of cancer. However, more research is needed to confirm these potential benefits.
A forehead, in medical terms, refers to the portion of the human skull that lies immediately above the eyes and serves as an attachment site for the frontal bone. It is a common area for the examination of various clinical signs, such as assessing the level of consciousness (by checking if the patient's eyebrows or eyelids twitch in response to a light touch) or looking for signs of increased intracranial pressure (such as bulging fontanelles in infants). Additionally, the forehead is often used as a site for non-invasive procedures like Botox injections.
Isotretinoin is a derivative of vitamin A, used in the treatment of severe recalcitrant nodular acne that has not responded to other therapies. It is a potent inhibitor of sebaceous gland function and keratinization. Isotretinoin is also known to have anti-inflammatory properties. It is taken orally in the form of capsules and its use requires careful monitoring due to potential teratogenic effects and other side effects, such as dryness of the skin and mucous membranes, mood changes, and liver enzyme abnormalities.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
Medical definitions of "lubricants" refer to substances that are used to reduce friction between two surfaces in medical procedures or devices. They can be used during various medical examinations, surgeries, or when inserting medical equipment, such as catheters, to make the process smoother and more comfortable for the patient.
Lubricants used in medical settings may include water-based gels, oil-based jellies, or silicone-based lubricants. It's important to choose a lubricant that is safe and suitable for the specific medical procedure or device being used. For example, some lubricants may not be compatible with certain medical materials or may need to be sterile.
It's worth noting that while lubricants are commonly used in medical settings, they should not be used as a substitute for proper medical care or treatment. If you have any concerns about your health or medical condition, it's important to consult with a qualified healthcare professional.
I'm sorry for the confusion, but "telescopes" is not a medical term. A telescope is an optical instrument that makes distant objects appear closer and larger by using an arrangement of lenses or mirrors and curved surfaces to gather and focus light. It is commonly used in astronomy to observe celestial bodies. If you have any questions related to medical terminology, I would be happy to help!
A nose, in a medical context, refers to the external part of the human body that is located on the face and serves as the primary organ for the sense of smell. It is composed of bone and cartilage, with a thin layer of skin covering it. The nose also contains nasal passages that are lined with mucous membranes and tiny hairs known as cilia. These structures help to filter, warm, and moisturize the air we breathe in before it reaches our lungs. Additionally, the nose plays an essential role in the process of verbal communication by shaping the sounds we make when we speak.
Dental polishing is a procedure in dentistry that is performed to smooth and clean the surfaces of teeth after professional dental cleaning (prophylaxis), restoration, or other dental treatments. It is usually done using a slow-speed handpiece with a soft, rubber cup attached to it, which holds a polishing paste or a slurry of pumice and water. The polishing paste may contain an abrasive agent, fluoride, or a flavoring agent. The dental professional moves the handpiece in a circular motion over the tooth surface to remove stains, plaque, and minor surface roughness, leaving the teeth smooth and shiny. Dental polishing helps to prevent the buildup of plaque and tartar, reduce the risk of decay and gum disease, and improve the overall oral hygiene and aesthetics of the teeth.
Nasal sebum
Triadica sebifera
Comedo
Dicarboxylic acid
Complete androgen insensitivity syndrome
Skin appendage
Montenegro in the Eurovision Song Contest 2017
Alfatradiol
Skin secretions (human)
Exocrine gland
Melanocortin 5 receptor
Sebacic acid
Dihydrotestosterone
Hair conditioner
Nicotinamide
Icosane
Pharmacodynamics of spironolactone
Perillaldehyde
Pimple
Carotenosis
Sapienic acid
Acne
Moisturizer
Toll-like receptor 2
Smegma
Parasitism
Jessie Marmorston
Moll's gland
Squalene
Silicon dioxide
Nasal sebum - Wikipedia
Dermalogica Sebum Clearing Masque 75ml - LOOKFANTASTIC
Patent Pick: Sensorial Sebum Absorption | Cosmetics & Toiletries
Skincare - Visible pores & sebum excess
What Is Sebum? - Beauty Bay Edited
What Is Sebum and What Is Its Purpose? - Acne.org
Sebum Plugs: Causes & Treatments + How To Get Rid Of Them For Good | mindbodygreen
Korean Face Sebum Powder | uSHOPS - UShops
Gerovital | Stop Acnee | Crema-gel sebum control 50ml | Mega-image
1,450 nm diode laser cuts sebum production
Sebum - Ritology
Normalizing shampoo - SEBUM
SEBUM SYNTHESIS - SKIN PHARMACY
Sebum Regulating Line | CRLAB
scratching sebum off scalp
secretion of sebum | Martin & Pleasance
CVPro SEBUM CONTROL LOTION - Indiglobalshop
Sebum Clearing Masque | Touch Bda
Pore Tightening Anti Sebum Pad
Innisfree No Sebum Mineral Powder - PinknBlossom
Sebum, pori, puncte negre - kazumi.ro
Shiseido Sebum & Oil Blotting Paper - Shoppurebeauty
Balance Sebum Control Shampoo | BMF Singapore
ETUDE Sebum Soak Pact 9.5g
SEBUM CLEANSER FOAM - Idraet Proshop Nordelta
Sebum-Balancing Mask (Impacco Seboequilibrante) - Phitofilos
RP EKS SEBUM BALANCING SHAMPOO 250ML
Sebaceous15
- Sebum is produced by sebaceous glands from the skin. (wikipedia.org)
- Sebum is an oily, waxy substance produced by our sebaceous glands. (beautybay.com)
- Produced in glands called sebaceous glands, which surround hair follicles, sebum moisturizes and waterproofs the skin, protects it against cold and microorganisms, and distributes antioxidants and hormones on the surface of the skin. (acne.org)
- Sebaceous glands are already formed and actively producing sebum while we are still in the womb. (acne.org)
- Only mammals have sebaceous glands, and thus, sebum. (acne.org)
- That buildup you may be facing might actually be sebum plugs (also characterized as sebaceous plugs or sebaceous hyperplasia), which require a slightly different plan of action. (mindbodygreen.com)
- Essentially, it's all in the name: Sebum plugs occur when sebum is quite literally plugging your sebaceous glands (a fancy term for pores). (mindbodygreen.com)
- While they're most common on the nose, chin, and forehead, says board-certified dermatologist Hadley King, M.D. , sebum plugs can be found anywhere on the body that has sebaceous glands (i.e., everywhere except the palms of your hands and soles of your feet). (mindbodygreen.com)
- Sebum is an oily substance produced in your sebaceous glands. (ritology.co)
- In fact, that 'greasy look' is caused by an excess of sebum produced by glands on the scalp known as the sebaceous glands. (crlab.com)
- It contains ingredients such as Jojoba extract (the makeup of which is very similar to our natural sebum), Avocado extract , which regulates sebaceous production, Laminaria and Larch Mushroom extracts , which have an extraordinary astringent capacity that prevents hair from becoming heavy due to excess sebum, Azelaic Acid , which combines powerful antimicrobial activity with an astringent effect that reduces sebaceous production. (crlab.com)
- Hyperseborrhea or hypersecretion of sebum is simply a scalp problem due to an excessive production of sebum caused by hyperactivity of the sebaceous glands. (audioimages.tv)
- Sebum is the oil produced in the sebaceous glands of the scalp. (audioimages.tv)
- Sebaceous glands on your scalp secrete natural oil called sebum. (audioimages.tv)
- Massaging stimulates your sebaceous glands by increasing the blood circulation in your scalp, therefore encouraging new sebum production. (audioimages.tv)
Human sebum3
- Human sebum is unique in this composition and differs from other mammals. (acne.org)
- It is a wax-like substance that mimics human sebum in the composition. (audioimages.tv)
- Dr. Carolyn S. McBride, one of the lead researchers on the study, said that breakdown products of human sebum likely trigger the "human-detecting" glomeruli of the Aedes aegypti mosquitoes that her team studied. (medlineplus.gov)
Shampoo4
- Treating shampoo with normalizing and purifying action based on sebum-modulating substances and natural extracts of Eucalyptus and Nettle. (vitalfarco.com)
- Also, I don't find that shampoo removes the sebum from my scalp. (audioimages.tv)
- Bask in the refreshing sensation of a deeply cleansed scalp, free from sebum or stubborn build-up with this scalp balancing shampoo. (bmf.com.sg)
- This shampoo provides sebum-regulating care which treats greasy scalps using high-quality natural ingredients and reduces sebum production. (lifemartini.com)
Innisfree3
- Das Innisfree No Sebum Powder Cushion bietet eine 48 Stunden lang anhaltende, hervorragende Deckkraft. (littlewonderland.de)
- Home / Skincare / Face Care / Innisfree Tone Up No Sebum. (anonnas.com)
- Be the first to review "Innisfree Tone Up No Sebum. (anonnas.com)
Powder14
- Welcome to the world of Korean Sebum Powder, the ultimate solution for Asian women in North America seeking flawless and shine-free skin. (ushops.com)
- This comprehensive guide will delve into the myriad aspects of Korean Sebum Powder, providing you with insights on its origin, ingredients, benefits, application techniques, and much more. (ushops.com)
- Asian women in North America have witnessed a beauty revolution with the introduction of Korean Sebum Powder. (ushops.com)
- Korean Sebum Powder represents a fusion of advanced technology and natural ingredients, carefully curated to address the unique challenges faced by Asian women in North America. (ushops.com)
- Korean Sebum Powder offers a breakthrough solution by effectively absorbing excess oil, leaving your skin with a beautiful matte finish. (ushops.com)
- The effectiveness of Korean Sebum Powder lies in its scientifically curated blend of ingredients. (ushops.com)
- Natural extracts such as green tea, witch hazel, and bamboo charcoal are key ingredients found in Korean Sebum Powder. (ushops.com)
- The integration of advanced technologies in Korean Sebum Powder ensures that it delivers exceptional results. (ushops.com)
- Transparent, Sebum Free, Lightweight New Sebum Soak Powder. (kiokii.com)
- Single-component powder specialized for sebum adsorption, quickly absorbs oil to create matte skin. (kiokii.com)
- Take an appropriate amount to the puff and tap it on the back of your hand to get the extra powder out, and tap it on the area where sebum is concerned. (kiokii.com)
- Formulated with sebum control powder, Jeju natural mineral and mint extracts. (korendy.com)
- In the last stage of your daily skincare routine or makeup, use powder puff to gently apply onto entire face or sebum concentrated areas. (korendy.com)
- Sebum control powder provides long-lasting makeup without darkening or smudging. (jolse.com)
Measured sebum production1
- Bilateral sebum measurements preceded each session, and immediately after each treatment, investigators also measured sebum production as described above. (dermatologytimes.com)
Secretion of sebum1
- The double sebum-control system controls the secretion of sebum to keep the skin soft and fresh all day long.2. (wynora.com)
Pores5
- A oil-absorbing blend of Kaolin and Bentonite clays act as a magnet to dirt, impurities and sebum, drawing it out of pores to be removed, making way for acne-busting Salicylic Acid to work its magic. (lookfantastic.com)
- Everywhere on our body, our pores produce sebum, that yellow oil necessary for keeping our skin and hair moisturized. (mindbodygreen.com)
- The difference between them is blackheads are considered "open" pores (and due to the oxidation of the plug, King notes, they turn darker), while sebum plugs may have no color at all. (mindbodygreen.com)
- Salicylic acid is an excellent comedolytic, or pore-clearing, ingredient because it exfoliates the stratum corner (the surface of the skin) and penetrates into pores to remove sebum. (mindbodygreen.com)
- Sebum production, a common concern among Asian women, can lead to unwanted shine and clogged pores. (ushops.com)
Produce sebum1
- Humans aren't the only animals that produce sebum, but its specific makeup varies across different species. (medlineplus.gov)
Excessive sebum1
- But it could also be excessive sebum buildup, and I can't figure out the difference between the two. (audioimages.tv)
Overproduction7
- This is especially true if you're stuck in a cycle of sebum overproduction, which can lead to oiliness and breakouts. (beautybay.com)
- An overproduction of sebum can lead to things like oiliness and breakouts, which is one of the main reasons why it has such a bad rep. (beautybay.com)
- If you've just discovered that you are dealing with an overproduction of sebum, your next question is most likely to be: how can I help curb it? (beautybay.com)
- The chemical build up from different hair care products disturbs your scalp pH, causing overproduction of sebum and scalp smell. (audioimages.tv)
- Dandruff is often caused by the overproduction of sebum. (audioimages.tv)
- Jojoba oil can also lower the risk of flakiness in dandruff by controlling the overproduction of scalp sebum. (audioimages.tv)
- Active amino acid complexes such as Tiolisina Complex and natural botanical oils work in close tandem to cleanse scalp of build-up, regulate overproduction of sebum and delivering deep conditioning of the hair. (bmf.com.sg)
Waxy substance made1
- Next, the research team took a closer look at the specific chemical compounds in the odors that lit up the "human-detecting" glomeruli and narrowed in on a substance called "sebum," an oily and somewhat waxy substance made by skin and hair follicles that coats and protects the skin from harm. (medlineplus.gov)
Lotion1
- Textura ultrasuave ◾ Piel limpia y matificada Complementala con la nueva Sebum Control Lotion para una piel fresca, sin brillo y libre de acné! (idraetproinstitute.com)
Skin19
- Love it or hate it (and you most likely hate it) sebum is an essential part of your skin. (beautybay.com)
- Sebum Is the Medical Name for Skin Oil. (acne.org)
- Sebum (skin oil) is essential to maintaining the integrity and function of the skin and hair in mammals, including humans. (acne.org)
- It is accepted science that skin that produces an excess amount of sebum is more prone to acne . (acne.org)
- Sebum (skin oil) is often seen as an annoyance because too much sebum usually leads to more acne. (acne.org)
- However, the sebum which coats the skin and hair of all mammals is important. (acne.org)
- Sebum is made up of lipids (fats) in different proportions that combine to protect the surface of the skin. (acne.org)
- For now, scientists theorize that when UV rays from the sun hit the skin, some lipids in sebum convert into free radicals, which are natural toxins that can trigger inflammation. (acne.org)
- When you have an excess of sebum mixed with dead skin cells and bacteria, that buildup can block the oil from reaching the surface of your skin. (mindbodygreen.com)
- Each component plays a vital role in achieving optimal sebum control and maintaining healthy, radiant skin. (ushops.com)
- Bamboo charcoal acts as a powerful absorbent, drawing out impurities and excess sebum, leaving your skin refreshed and revitalized. (ushops.com)
- Sebum is made to coat, moisturise and protect our skin. (ritology.co)
- The skin tries to get rid of the dead cells, which, not being able to reach a complete growth, come off … The research on how sebum levels influence Malassezia activity is confounding. (audioimages.tv)
- Sebum in surplus brings about an accelerated replacement of the skin cells and a desquamation of the scalp. (audioimages.tv)
- The sebum-balancing mask is a major asset against acne, oily skin and impurities related to your daily life. (cosmeto-nature.com)
- Say Hello to Clear Skin - Embrace a blemish-free complexion as our formula regulates hormones and controls sebum, promoting clear skin and optimal hormone balance for women. (etcly.com)
- An unctuous substance composed of sebum and desquamated epithelial cells, which covers the skin of the fetus. (bvsalud.org)
- The objective of this study was to compare particle transfer and adherence to cotton gloves, cotton gloves with artificial sebum, and a pre-moistened polyvinyl alcohol (PVA) material with bare human skin (fingertip, palm). (cdc.gov)
- For particle mass transfer, compared with bare skin, bias was -77% (cotton glove with sebum) to +197% (PVA material) and for adherence bias ranged from -40% (cotton glove) to +428% (PVA material), which indicated under- and over-sampling by these substrates, respectively. (cdc.gov)
Regulating2
- CRLAB's Sebum Regulating Yellow Line has been designed and tested to regulate sebum production and eliminate oily dandruff. (crlab.com)
- How to apply the sebum regulating mask? (cosmeto-nature.com)
Inflammation1
- Treatment, based on severity, can involve a variety of topical and systemic agents directed at reducing sebum production, comedone formation, inflammation, and bacterial counts and at normalizing keratinization. (msdmanuals.com)
Acne-prone1
- Sebum production is also kicked into gear by hormones, which explains why teenagers, who are at the height of hormone changes, are more acne-prone. (beautybay.com)
Production11
- Sebum production is highest during our teenage years and then tends to decline with age. (beautybay.com)
- This explains why acne occurs at stages in life, like puberty, when the production of sebum can go into overdrive. (acne.org)
- A recent study shows, for perhaps the first time, that the 1,450 nm diode laser's mechanism of action against acne vulgaris involves reducing sebum production, as clinicians have long suspected, the study's lead researcher says. (dermatologytimes.com)
- Boston - A small study appears to confirm the 1,450 nm diode laser's suspected mechanism of action in treating acne: reducing sebum production. (dermatologytimes.com)
- After establishing the baseline for sebum production, researchers performed three treatments, spaced two weeks apart, on the right side of each patient's nose with the 1,450 nm diode laser. (dermatologytimes.com)
- We found that the 1,450 nm diode laser does seem to have an effect on sebum production. (dermatologytimes.com)
- Although sebum production is completely normal and healthy, too much or too little can cause problems. (ritology.co)
- Sebum is particularly important for the nourishment and hydration of the hair, but sometimes hormones, stress or the wrong kind of diet can throw sebum production out of whack, and too much of it is produced. (crlab.com)
- 5. Massaging your scalp on a daily basis is a vital step in helping/encouraging new sebum production. (audioimages.tv)
- During puberty, surges in androgens stimulate sebum production and hyperproliferation of keratinocytes. (msdmanuals.com)
- Some humans create more sebum than others, and your sebum production can be influenced by factors such as age, medications, and lifestyle. (medlineplus.gov)
Follicles2
- And if you're facing some sebum plugs on your scalp, a chemical scalp scrub may help give your hair follicles a necessary tune-up. (mindbodygreen.com)
- rsb.info.nih.gov/ij/ ), which counted both the number of sebum-producing follicles and the area or volume of sebum absorbed into the tape. (dermatologytimes.com)
Reduces1
- It has a mild, pleasant, non-clammy structure, with a rapid absorption, which reduces the sebum excess and restores the feeling of comfort. (gerovital.net)
Lipids2
- Sebum has a complex composition that is different from epidermal lipids found anywhere in the human body, for example, squalene and wax esters are only found in sebum. (wikipedia.org)
- The least abundant lipid in sebum is cholesterol, which with its esters, accounts for the 4.5% of total lipids. (wikipedia.org)
Cleanser1
- SEBUM CLEANSER FOAM Espuma de limpieza Profunda. (idraetproinstitute.com)
Makeup1
- It was created through the hands of the collective intelligence of the national BMs who were worried about makeup that cakes easily due to excess sebum. (kiokii.com)
Buildup1
- So, in short, sebum buildup can cause hair loss. (audioimages.tv)
Composition1
- Researchers suggest that the individual differences in sebum composition may hold the key to a person's chemical signature, potentially showing how dogs can recognize people after sniffing them. (acne.org)
Skincare1
- Rooted in the renowned Korean skincare philosophy, this remarkable product has transformed the way we approach sebum control and shine reduction. (ushops.com)
Whiteheads4
- Simply put, sebum plugs are the foundation for blackheads and whiteheads. (mindbodygreen.com)
- Meaning, blackheads and whiteheads are later iterations of sebum plugs once they become inflamed. (mindbodygreen.com)
- So while you may notice a blackhead in the mirror, the root of the problem is a sebum plug, which is what you'll want to treat to keep those blackheads (and whiteheads, for that matter) at bay. (mindbodygreen.com)
- Excess sebum will result to formation of blackheads, whiteheads, pimples and more severe types of acne. (audioimages.tv)
Ingredients1
- It contains active ingredients that absorb excess sebum and create a dermo-protective barrier. (cosmeto-nature.com)
Dandruff1
- At this point, there will be patches of salicylic acid peeling off any sebum, dandruff, and dirt from your scalp. (audioimages.tv)
Plugs9
- Here, everything you need to know about sebum plugs, plus the best ways to get rid of them for good. (mindbodygreen.com)
- What are sebum plugs, and why do they happen? (mindbodygreen.com)
- Your back, chest, and scalp are also common hotbeds for sebum plugs, but there are also other places (albeit, unlikely) they can pop up as well. (mindbodygreen.com)
- Sebum plugs versus blackheads. (mindbodygreen.com)
- How to treat sebum plugs-the do's and don'ts. (mindbodygreen.com)
- Annoying, yes, but sebum plugs are not cause for alarm. (mindbodygreen.com)
- According to Ross, exfoliating regularly is perhaps the best way to treat sebum plugs and keep them from popping up. (mindbodygreen.com)
- Since sebum plugs are caused by oil, your best bet will be BHAs. (mindbodygreen.com)
- If you suffer from hair loss as well as a particularly oily scalp, it's important to first heal the scalp, freeing it from sebum plugs before starting our specific anti-hair loss treatment - the CRLAB Hair Loss Prevention Green Line. (crlab.com)
Treatments2
- The maximal effect was a statistically significant reduction in sebum output of 18 percent after three treatments, Dr. Perez-Maldonado adds. (dermatologytimes.com)
- Light scalp exfoliation is okay, just be … How To Treat Excess Sebum Of Scalp Effectively Washing and shampooing the hair are some of the first things which will come to your mind on the subject of hair treatments. (audioimages.tv)
Combines1
- This sebum combines with sweat and slowly evaporates into the air, which affects the way we smell-our "odor. (medlineplus.gov)