AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
SARS VirusSevere Acute Respiratory SyndromeSpike Glycoprotein, CoronavirusNucleocapsid ProteinsRNA VirusesVaccinia virusReceptors, VirusVirus ReplicationVirus CultivationVirus SheddingVirus DiseasesSimian virus 40Virus AssemblyPlant VirusesDNA VirusesDefective VirusesSindbis VirusMeasles virusInfluenza A Virus, H1N1 SubtypeRabies virusInfluenza A Virus, H5N1 SubtypeInfluenza A Virus, H3N2 SubtypeHepatitis B virusWest Nile virusRNA, ViralVero CellsRespiratory Syncytial VirusesDisease OutbreaksAntigens, ViralViral ProteinsCercopithecus aethiopsGenes, ViralVirus ActivationVesicular stomatitis Indiana virusVirus LatencyHemagglutinin Glycoproteins, Influenza Virus
SARS Virus
A species of CORONAVIRUS causing atypical respiratory disease (SEVERE ACUTE RESPIRATORY SYNDROME) in humans. The organism is believed to have first emerged in Guangdong Province, China, in 2002. The natural host is the Chinese horseshoe bat, RHINOLOPHUS sinicus.
Severe Acute Respiratory Syndrome
A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent.
Spike Glycoprotein, Coronavirus
A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.
Nucleocapsid Proteins
Viral proteins found in either the NUCLEOCAPSID or the viral core (VIRAL CORE PROTEINS).
RNA Viruses
Viruses whose genetic material is RNA.
Vaccinia virus
The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.
Receptors, Virus
Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response.
Virus Replication
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
Virus Cultivation
Process of growing viruses in live animals, plants, or cultured cells.
Virus Shedding
The expelling of virus particles from the body. Important routes include the respiratory tract, genital tract, and intestinal tract. Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).
Virus Diseases
A general term for diseases produced by viruses.
Simian virus 40
A species of POLYOMAVIRUS originally isolated from Rhesus monkey kidney tissue. It produces malignancy in human and newborn hamster kidney cell cultures.
Virus Assembly
The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.
Plant Viruses
Viruses parasitic on plants higher than bacteria.
DNA Viruses
Viruses whose nucleic acid is DNA.
Defective Viruses
Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.
Sindbis Virus
The type species of ALPHAVIRUS normally transmitted to birds by CULEX mosquitoes in Egypt, South Africa, India, Malaya, the Philippines, and Australia. It may be associated with fever in humans. Serotypes (differing by less than 17% in nucleotide sequence) include Babanki, Kyzylagach, and Ockelbo viruses.
Measles virus
The type species of MORBILLIVIRUS and the cause of the highly infectious human disease MEASLES, which affects mostly children.
Influenza A Virus, H1N1 Subtype
A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 1 and neuraminidase 1. The H1N1 subtype was responsible for the Spanish flu pandemic of 1918.
Rabies virus
The type species of LYSSAVIRUS causing rabies in humans and other animals. Transmission is mostly by animal bites through saliva. The virus is neurotropic multiplying in neurons and myotubes of vertebrates.
Influenza A Virus, H5N1 Subtype
A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 5 and neuraminidase 1. The H5N1 subtype, frequently referred to as the bird flu virus, is endemic in wild birds and very contagious among both domestic (POULTRY) and wild birds. It does not usually infect humans, but some cases have been reported.
Influenza A Virus, H3N2 Subtype
A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 3 and neuraminidase 2. The H3N2 subtype was responsible for the Hong Kong flu pandemic of 1968.
Hepatitis B virus
The type species of the genus ORTHOHEPADNAVIRUS which causes human HEPATITIS B and is also apparently a causal agent in human HEPATOCELLULAR CARCINOMA. The Dane particle is an intact hepatitis virion, named after its discoverer. Non-infectious spherical and tubular particles are also seen in the serum.
West Nile virus
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE). It can infect birds and mammals. In humans, it is seen most frequently in Africa, Asia, and Europe presenting as a silent infection or undifferentiated fever (WEST NILE FEVER). The virus appeared in North America for the first time in 1999. It is transmitted mainly by CULEX spp mosquitoes which feed primarily on birds, but it can also be carried by the Asian Tiger mosquito, AEDES albopictus, which feeds mainly on mammals.
RNA, Viral
Ribonucleic acid that makes up the genetic material of viruses.
Vero Cells
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
Respiratory Syncytial Viruses
A group of viruses in the PNEUMOVIRUS genus causing respiratory infections in various mammals. Humans and cattle are most affected but infections in goats and sheep have also been reported.
Disease Outbreaks
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
Antigens, Viral
Substances elaborated by viruses that have antigenic activity.
Viral Proteins
Proteins found in any species of virus.
Cercopithecus aethiops
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
Genes, Viral
The functional hereditary units of VIRUSES.
Virus Activation
The mechanism by which latent viruses, such as genetically transmitted tumor viruses (PROVIRUSES) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. It may be effected by various endogenous and exogenous stimuli, including B-cell LIPOPOLYSACCHARIDES, glucocorticoid hormones, halogenated pyrimidines, IONIZING RADIATION, ultraviolet light, and superinfecting viruses.
Vesicular stomatitis Indiana virus
The type species of VESICULOVIRUS causing a disease symptomatically similar to FOOT-AND-MOUTH DISEASE in cattle, horses, and pigs. It may be transmitted to other species including humans, where it causes influenza-like symptoms.
Virus Latency
The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.
Hemagglutinin Glycoproteins, Influenza Virus
Membrane glycoproteins from influenza viruses which are involved in hemagglutination, virus attachment, and envelope fusion. Fourteen distinct subtypes of HA glycoproteins and nine of NA glycoproteins have been identified from INFLUENZA A VIRUS; no subtypes have been identified for Influenza B or Influenza C viruses.

Identification of a novel coronavirus in patients with severe acute respiratory syndrome. (1/1050)

BACKGROUND: The severe acute respiratory syndrome (SARS) has recently been identified as a new clinical entity. SARS is thought to be caused by an unknown infectious agent. METHODS: Clinical specimens from patients with SARS were searched for unknown viruses with the use of cell cultures and molecular techniques. RESULTS: A novel coronavirus was identified in patients with SARS. The virus was isolated in cell culture, and a sequence 300 nucleotides in length was obtained by a polymerase-chain-reaction (PCR)-based random-amplification procedure. Genetic characterization indicated that the virus is only distantly related to known coronaviruses (identical in 50 to 60 percent of the nucleotide sequence). On the basis of the obtained sequence, conventional and real-time PCR assays for specific and sensitive detection of the novel virus were established. Virus was detected in a variety of clinical specimens from patients with SARS but not in controls. High concentrations of viral RNA of up to 100 million molecules per milliliter were found in sputum. Viral RNA was also detected at extremely low concentrations in plasma during the acute phase and in feces during the late convalescent phase. Infected patients showed seroconversion on the Vero cells in which the virus was isolated. CONCLUSIONS: The novel coronavirus might have a role in causing SARS.  (+info)

A novel coronavirus associated with severe acute respiratory syndrome. (2/1050)

BACKGROUND: A worldwide outbreak of severe acute respiratory syndrome (SARS) has been associated with exposures originating from a single ill health care worker from Guangdong Province, China. We conducted studies to identify the etiologic agent of this outbreak. METHODS: We received clinical specimens from patients in seven countries and tested them, using virus-isolation techniques, electron-microscopical and histologic studies, and molecular and serologic assays, in an attempt to identify a wide range of potential pathogens. RESULTS: None of the previously described respiratory pathogens were consistently identified. However, a novel coronavirus was isolated from patients who met the case definition of SARS. Cytopathological features were noted in Vero E6 cells inoculated with a throat-swab specimen. Electron-microscopical examination revealed ultrastructural features characteristic of coronaviruses. Immunohistochemical and immunofluorescence staining revealed reactivity with group I coronavirus polyclonal antibodies. Consensus coronavirus primers designed to amplify a fragment of the polymerase gene by reverse transcription-polymerase chain reaction (RT-PCR) were used to obtain a sequence that clearly identified the isolate as a unique coronavirus only distantly related to previously sequenced coronaviruses. With specific diagnostic RT-PCR primers we identified several identical nucleotide sequences in 12 patients from several locations, a finding consistent with a point-source outbreak. Indirect fluorescence antibody tests and enzyme-linked immunosorbent assays made with the new isolate have been used to demonstrate a virus-specific serologic response. This virus may never before have circulated in the U.S. population. CONCLUSIONS: A novel coronavirus is associated with this outbreak, and the evidence indicates that this virus has an etiologic role in SARS. Because of the death of Dr. Carlo Urbani, we propose that our first isolate be named the Urbani strain of SARS-associated coronavirus.  (+info)

Epidemiology, clinical presentation and laboratory investigation of severe acute respiratory syndrome (SARS) in Canada, March 2003. (3/1050)

As of 23 March, 2003, 11 cases of SARS have been reported in Canada. Three patients had travelled to China, including Hong Kong SAR. The remaining eight had a history of close contact with cases. There have been three deaths. To date, evidence for human metapneumovirus has been found in six cases; further studies are ongoing to determine whether this virus is the causative agent of the SARS or whether other, so far undetected, pathogens are responsible. Public health measures are being implemented at the local, provincial, and national levels to identify new cases and prevent secondary transmission of SARS.  (+info)

Update: outbreak of severe acute respiratory syndrome--worldwide, 2003. (4/1050)

CDC and the World Health Qrganization (WHO) are continuing to investigate the multicountry outbreak of unexplained atypical pneumonia referred to as severe acute respiratory syndrome (SARS). Pending development of confirmatory laboratory testing capacity, CDC's interim suspected SARS case definition is based on clinical criteria and epidemiologic linkage to other SARS cases or areas with community transmission of SARS. This case definition will be updated periodically as new information becomes available. Epidemiologic and laboratory investigations of SARS are ongoing. As of April 2, 2003, a total of 2,223 suspected and/or probable SARS cases have been reported to WHO from 16 countries, including the United States. The reported SARS cases include 78 deaths (case-fatality proportion: 3.5%). This report summarizes SARS cases among U.S. residents and surveillance and prevention activities in the United States.  (+info)

Characterization of a novel coronavirus associated with severe acute respiratory syndrome. (5/1050)

In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratory syndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, and the initial characterization of the viral genome is presented in this report. The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is similar to that of other coronaviruses. Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closely related to any of the previously characterized coronaviruses.  (+info)

The Genome sequence of the SARS-associated coronavirus. (6/1050)

We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)-associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this coronavirus is only moderately related to other known coronaviruses, including two human coronaviruses, HCoV-OC43 and HCoV-229E. Phylogenetic analysis of the predicted viral proteins indicates that the virus does not closely resemble any of the three previously known groups of coronaviruses. The genome sequence will aid in the diagnosis of SARS virus infection in humans and potential animal hosts (using polymerase chain reaction and immunological tests), in the development of antivirals (including neutralizing antibodies), and in the identification of putative epitopes for vaccine development.  (+info)

Severe acute respiratory syndrome (SARS) and coronavirus testing--United States, 2003. (7/1050)

CDC and the World Health Organization (WHO) are continuing to investigate the multicountry outbreak of severe acute respiratory syndrome (SARS). Infection with a novel coronavirus has been implicated as a possible cause of SARS. This report updates information on U.S. residents with SARS and summarizes the clinical histories of the five U.S. residents identified as of April 9, 2003, who have both suspected SARS and laboratory evidence of infection with a novel coronavirus.  (+info)

Update: Severe acute respiratory syndrome--United States, 2003. (8/1050)

CDC and the World Health Organization (WHO) are continuing to investigate the multicountry outbreak of severe acute respiratory syndrome (SARS). This report updates information on reported SARS cases among U.S. residents and summarizes information on patients with no recent travel outside the United States.  (+info)

Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S...Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S...
TY - JOUR. T1 - Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S incorporation into virus-like particles, but not for M-S co-localization. AU - Ujike, Makoto. AU - Huang, Cheng. AU - Shirato, Kazuya. AU - Matsuyama, Shutoku. AU - Makino, Shinji. AU - Taguchi, Fumihiro. PY - 2012/4. Y1 - 2012/4. N2 - The endodomain of several coronavirus (CoV) spike (S) proteins contains palmitylated cysteine residues and enables co-localization and interaction with the CoV membrane (M) protein. Depalmitylation of mouse hepatitis virus S proteins abolished this interaction, resulting in the failure of S incorporation into virions. In contrast, an immunofluorescence assay (IFA) showed that depalmitylated severe acute respiratory syndrome coronavirus (SCoV) S proteins still co-localized with the M protein in the budding site. Here, we determined the ability of depalmitylated SCoV S mutants to incorporate S into virus-like particles (VLPs). ...
https://researchexperts.utmb.edu/en/publications/two-palmitylated-cysteine-residues-of-the-severe-acute-respirator
Quantitation of severe acute respiratory syndrome coronavirus genome by real-time polymerase chain reaction assay using minor...
TY - JOUR. T1 - Quantitation of severe acute respiratory syndrome coronavirus genome by real-time polymerase chain reaction assay using minor groove binder DNA probe technology. AU - Lin, Hsi Hsun. AU - Wang, Shiow J.. AU - Liu, Yung Ching. AU - Lee, S. S J. AU - Hwang, Chun K.. AU - Chen, Yao Shen. AU - Wann, Shue R.. AU - Shih, Yi L.. PY - 2004/10. Y1 - 2004/10. N2 - The ability to rapidly recognize severe acute respiratory syndrome coronavirus (SARS-CoV) as a cause of infections is critical to quickly limiting further spread of the disease. A rapid, sensitive, and specific laboratory diagnostic test is needed to confirm outbreaks of SARS-CoV infection and distinguish it from other diseases that can cause similar clinical symptoms. An improved TaqMan technology using minor groove binder (MGB) probes was used to detect and quantify SARS-CoV in suspected patients. SARS-CoV primers and probe were designed based on the open reading frame 1b sequence, which encodes coronavirus replicase protein. A ...
https://tmu.pure.elsevier.com/en/publications/quantitation-of-severe-acute-respiratory-syndrome-coronavirus-gen
Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19, and the Renin-Angiotensin System | HypertensionSevere Acute Respiratory Syndrome Coronavirus 2, COVID-19, and the Renin-Angiotensin System | Hypertension
The coronavirus disease 2019 (COVID-19) pandemic is associated with significant morbidity and mortality throughout the world, predominantly due to lung and cardiovascular injury. The virus responsible for COVID-19-severe acute respiratory syndrome coronavirus 2-gains entry into host cells via ACE2 (angiotensin-converting enzyme 2). ACE2 is a primary enzyme within the key counter-regulatory pathway of the renin-angiotensin system (RAS), which acts to oppose the actions of Ang (angiotensin) II by generating Ang-(1-7) to reduce inflammation and fibrosis and mitigate end organ damage. As COVID-19 spans multiple organ systems linked to the cardiovascular system, it is imperative to understand clearly how severe acute respiratory syndrome coronavirus 2 may affect the multifaceted RAS. In addition, recognition of the role of ACE2 and the RAS in COVID-19 has renewed interest in its role in the pathophysiology of cardiovascular disease in general. We provide researchers with a framework of best practices ...
https://hypertension.hub.heart.org/hypertension/news/21199796/severe-acute-respiratory-syndrome-coronavirus-2-covid19-and-the-reninangiotensin-system
Severe Acute Respiratory Syndrome-associated Coronavirus in Lung Tissue - Volume 10, Number 1-January 2004 - Emerging...
Efforts to contain severe acute respiratory syndrome (SARS) have been limited by the lack of a standardized, sensitive, and specific test for SARS-associated coronavirus (CoV). We used a standardized reverse transcription-polymerase chain reaction assay to detect SARS-CoV in lung samples obtained from well-characterized patients who died of SARS and from those who died of other reasons. SARS-CoV was detected in all 22 postmortem lung tissues (to 109 viral copies/g) from 11 patients with probable SARS but was not detected in any of the 23 lung control samples (sample analysis was blinded). The sensitivity and specificity (95% confidence interval) were 100% (84.6% to 100%) and 100% (85.1% to 100%), respectively. Viral loads were significantly associated with a shorter course of illness but not with the use of ribavirin or steroids. CoV was consistently identified in the lungs of all patients who died of SARS but not in control patients, supporting a primary role for CoV in deaths.
https://wwwnc.cdc.gov/eid/article/10/1/03-0404_article
HKU Scholars Hub: Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cellsHKU Scholars Hub: Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS, which caused a global panic in 2003. We describe here the screening of Chinese herbal medicine-based, novel small molecules that bind avidly with the surface spike protein of SARS-CoV and thus can interfere with the entry of the virus to its host cells. We achieved this by using a two-step screening method consisting of frontal affinity chromatography-mass spectrometry coupled with a viral infection assay based on a human immunodeficiency virus (HIV)-luc/SARS pseudotyped virus. Two small molecules, tetra-O-galloyl-beta-D-glucose (TGG) and luteolin, were identified, whose anti-SARS-CoV activities were confirmed by using a wild-type SARS-CoV infection system. TGG exhibits prominent anti-SARS-CoV activity with a 50% effective concentration of 4.5 microM and a selective index of 240.0. The two-step screening method described here yielded several small molecules that can be used for developing new classes of ...
http://hub.hku.hk/handle/10722/49313
An Exposed Domain in the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Induces Neutralizing Antibodies | Journal...An Exposed Domain in the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Induces Neutralizing Antibodies | Journal...
Selecting from regions of the S protein of SARS CoV that are predicted to potentially present antigenic determinants, a small region (S-II) comprising residues 485 to 625 was expressed as a recombinant protein in E. coli. After proper refolding, the solubilized S-II fragment was shown to specifically bind the surface of Vero cells by FACS analysis. This suggests that antibodies against this region could give rise to neutralizing activities. A panel of MAbs was raised with the recombinant S-II protein. A series of tests showed that the MAbs could recognize the native S protein, block the attachment of S-II to Vero cells, and neutralize SARS CoV infection in cell culture.. Virus entry involves attachment of the S1 region to the host receptor and exposure of the fusion peptide that results from the conformational change induced by the interaction of the S1 region with the receptor. However, studies with HCoV 229E, MHV, and TGEV further defined polypeptide regions that can bind the host receptor. A ...
https://jvi.asm.org/content/78/13/7217?ijkey=38043c4aabc5e78f94698fde7a30bb3595f2fdb3&keytype2=tf_ipsecsha
Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome...Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently emerged to cause widespread infections in humans. SARS-CoV-2 infections have been reported in the Kingdom of Saudi Arabia, where Middle East respiratory syndrome coronavirus (MERS-CoV) causes seasonal outbreaks with a case fatality rate of ~37 %. Here we show that there exists a theoretical possibility of future recombination events between SARS-CoV-2 and MERS-CoV RNA. Through computational analyses, we have identified homologous genomic regions within the ORF1ab and S genes that could facilitate recombination, and have analysed co-expression patterns of the cellular receptors for SARS-CoV-2 and MERS-CoV, ACE2 and DPP4, respectively, to identify human anatomical sites that could facilitate co-infection. Furthermore, we have investigated the likely susceptibility of various animal species to MERS-CoV and SARS-CoV-2 infection by comparing known virus spike protein-receptor interacting residues. In conclusion, we suggest that a
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.001491
Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis |...Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis |...
1. PerlmanS, NetlandJ (2009) Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Microbiol 7: 439-450.. 2. RotaPA, ObersteMS, MonroeSS, NixWA, CampganoliR, et al. (2003) Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 300: 1394-1399.. 3. DrostenC, GuntherS, PreiserW, van der WerfS, BrodtHR, et al. (2003) Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 348: 1967-1976.. 4. PyrcK, BerkhoutB, van der HoekL (2007) The novel human coronaviruses NL63 and HKU1. J Virol 81: 3051-3057.. 5. ZakiAM, van BoheemenS, BestebroerTM, OsterhausAD, FouchierRA (2012) Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 367: 1814-1820.. 6. DanielssonN, CatchpoleM (2012) Novel coronavirus associated with severe respiratory disease: case definition and public health measures. Euro Surveill 17: 20282.. 7. AssiriA, McGeerA, PerlTM, PriceCS, Al RabeeahAA, et al. ...
https://www.prolekarniky.cz/casopisy/plos-pathogens/2014-5/severe-acute-respiratory-syndrome-coronavirus-envelope-protein-ion-channel-activity-promotes-virus-fitness-and-pathogenesis-53559
Dissertation or Thesis | Evaluations Of Severe Acute Respiratory Syndrome Coronavirus Therapeutics And A Viral Capacity For...Dissertation or Thesis | Evaluations Of Severe Acute Respiratory Syndrome Coronavirus Therapeutics And A Viral Capacity For...
The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) emerged in 2002/2003, causing the deaths of almost a tenth of the 8000 individuals infected worldwide before it was controlled by public health measures. While the 2003 epidemic strain is likely extinct, the importance of coronaviruses as emergent zoonotic viruses was again realized with the emergence of a novel human coronavirus in Saudi Arabia in 2012. Despite a decade of research on SARS-CoV no approved vaccine or therapeutic yet exists, and development of broadly neutralizing and effective therapeutics for coronaviruses remains a priority. Neutralizing antibodies targeting the Spike glycoprotein (S) are both necessary and sufficient for protection against SARS-CoV, but the high genetic diversity and mutability of SARS-CoV in natural infections presents a challenge to both vaccine- and antibody-based therapeutics. Thus, an effective SARS-CoV therapeutic should provide S-specific immunity that is nonetheless broad enough to counter ...
https://cdr.lib.unc.edu/concern/dissertations/n583xv508
HKU Scholars Hub: Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirusHKU Scholars Hub: Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus
Public health risks associated to infection by human coronaviruses remain considerable and vaccination is a key option for preventing the resurgence of severe acute respiratory syndrome coronavirus (SARS-CoV). We have previously reported that antibodies elicited by a SARS-CoV vaccine candidate based on recombinant, full-length SARS-CoV Spike-protein trimers, trigger infection of immune cell lines. These observations prompted us to investigate the molecular mechanisms and responses to antibody-mediated infection in human macrophages ...
http://hub.hku.hk/handle/10722/199800
The emerging pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 ...The emerging pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 ...
The emerging pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents an unprecedented challenge for healthcare systems globally. quickly underway to build up potential therapeutic real estate agents and vaccines (Antithrombotic Therapy, 2020; Coronavirus, 2020; Epidemiological, 2020; Lexicomp for Dentistry, 2020; Zhang et al., 2020). 8.1. Anti-viral real estate agents 8.1.1. Remdesivir Remdesivir was initially developed through the peak from XL413 the Ebola disease outbreak in 2016, and offers been proven to become the most guaranteeing therapy in dealing with COVID-19 (Ko et al., 2020; Sanders et al., 2020). It really is a broad-spectrum anti-viral agent that works as an inhibitor of RNA-dependent RNA polymerase, an enzyme necessary for viral replication (Fig. 1.) (Kupferschmidt, 2020). Although Remdesivir failed in medical tests for treatment of Ebola in 2014, it really is thought as a safe drug. Similar to the doses ...
http://vx-765.com/%EF%BB%BFthe-emerging-pandemic-of-coronavirus-disease-2019-covid-19-caused-by-the-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-presents-an-unprecedented-challenge-for-healthcare-syst/
Genome sequencing of a severe acute respiratory syndrome Coronavirus 2 isolate obtained from a South African patient with...Genome sequencing of a severe acute respiratory syndrome Coronavirus 2 isolate obtained from a South African patient with...
As a contribution to the global efforts to track and trace the ongoing coronavirus pandemic, here we present the sequence, phylogenetic analysis, and modeling of nonsynonymous mutations for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome that was detected in a South African patient with coronavirus disease 2019 (COVID-19 ...
http://repository.uwc.ac.za/handle/10566/5646?show=full
Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 From the Mother to the Infant | JAMA Pediatrics | JAMA...Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 From the Mother to the Infant | JAMA Pediatrics | JAMA...
To the Editor Coronavirus disease 2019 (COVID-19), which is caused by a new coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) emerged i
https://jamanetwork.com/journals/jamapediatrics/article-abstract/2768548
Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus...Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus...
UNLABELLED: The receptor binding domain (RBD) of the spike (S) glycoprotein of severe acute respiratory syndrome coronavirus (SARS-CoV) is a major target of protective immunity in vivo. Although a large number of neutralizing antibodies (nAbs) have been developed, it remains unclear if a single RBD-targeting nAb or two in combination can prevent neutralization escape and, if not, attenuate viral virulence in vivo. In this study, we used a large panel of human nAbs against an epitope that overlaps the interface between the RBD and its receptor, angiotensin-converting enzyme 2 (ACE2), to assess their cross-neutralization activities against a panel of human and zoonotic SARS-CoVs and neutralization escape mutants. We also investigated the neutralization escape profiles of these nAbs and evaluated their effects on receptor binding and virus fitness in vitro and in mice. We found that some nAbs had great potency and breadth in neutralizing multiple viral strains, including neutralization escape ...
http://pesquisa.bvsalud.org/portal/resource/en/mdl-25231316
Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and...
TY - JOUR. T1 - Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia. AU - Bloise, Enrrico. AU - Zhang, Jianhong. AU - Nakpu, Jittanan. AU - Hamada, Hirotaka. AU - Dunk, Caroline E.. AU - Li, Siliang. AU - Imperio, Guinever E.. AU - Nadeem, Lubna. AU - Kibschull, Mark. AU - Lye, Phetcharawan. AU - Matthews, Stephen G.. AU - Lye, Stephen J.. N1 - Funding Information: E.B. is supported by the Higher Education Personnel Improvement Coordination (Coordena??o de Aperfei?oamento Pessoal de N?vel Superior [CAPES]; finance code 001, CAPES-Print fellowship). S.J.L. is supported by a grant (FDN-143262) from the Canadian Institutes of Health Research (CIHR). S.G.M. is also supported by a grant (FDN-148368) from the CIHR. Funding Information: E.B. is supported by the Higher Education ...
https://tohoku.pure.elsevier.com/en/publications/expression-of-severe-acute-respiratory-syndrome-coronavirus-2-cel
Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target...Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target...
The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)in China threatened humankind worldwide. The coronaviruses contains the largest RNA genome among all other known RNA viruses, therefore the disease etiology can be understood by analyzing the genome sequence of SARS-CoV-2. In this study, we used an ab-intio based computational tool VMir to scan the complete genome of SARS-CoV-2 to predict pre-miRNAs. The potential pre-miRNAs were identified by ViralMir and mature miRNAs were recognized by Mature Bayes. Additionally, predicted mature miRNAs were analysed against human genome by miRDB server to retrieve target genes. Besides that we also retrieved GO (Gene Ontology) terms for pathways, functions and cellular components. We predicted 26 mature miRNAs from genome of SARS-CoV-2 that targets human genes involved in pathways like EGF receptor signaling, apoptosis signaling, VEGF signaling, FGF receptor signaling. Gene enrichment tool analysis and substantial literature
http://mbrc.shirazu.ac.ir/article_5664.html
Identifying epitopes responsible for neutralizing antibody and DC-SIGN binding on the spike glycoprotein of the severe acute...
TY - JOUR. T1 - Identifying epitopes responsible for neutralizing antibody and DC-SIGN binding on the spike glycoprotein of the severe acute respiratory syndrome coronavirus. AU - Shih, Yi Ping. AU - Chen, Chia Yen. AU - Liu, Shih Jen. AU - Chen, Kuan Hsuan. AU - Lee, Yuan Ming. AU - Chao, Yu Chan. AU - Chen, Yi Ming Arthur. PY - 2006/11/1. Y1 - 2006/11/1. N2 - The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) uses dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN) to facilitate cell entry via cellular receptor-angiotensin-converting enzyme 2. For this project, we used recombinant baculoviruses expressing different lengths of SARS-CoV spike (S) protein in a capture assay to deduce the minimal DC-SIGN binding region. Our results identified the region location between amino acid (aa) residues 324 to 386 of the S protein. We then generated nine monoclonal antibodies (MAbs) against the S protein to map the DC-SIGN-binding domain using capture assays with pseudotyped ...
https://tmu.pure.elsevier.com/en/publications/identifying-epitopes-responsible-for-neutralizing-antibody-and-dc
Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes...Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes...
The details of the mechanism by which severe acute respiratory syndrome-associated coronavirus (SARS-CoV) causes severe pneumonia are unclear. We investigated the immune responses and pathologies of SARS-CoV-infected BALB/c mice that were immunized intradermally with recombinant vaccinia virus (VV) …
https://pubmed.ncbi.nlm.nih.gov/18941225/
Get PDF - Diagnosis of severe acute respiratory syndrome (SARS) by detection of SARS coronavirus nucleocapsid antibodies in an...Get PDF - Diagnosis of severe acute respiratory syndrome (SARS) by detection of SARS coronavirus nucleocapsid antibodies in an...
Shi, Y.; Yi, Y.; Li, P.; Kuang, T.; Li, L.; Dong, M.; Ma, Q.; Cao, C., 2003: Diagnosis of severe acute respiratory syndrome (SARS) by detection of SARS coronavirus nucleocapsid antibodies in an antigen-capturing enzyme-linked immunosorbent assay
https://eurekamag.com/research/048/775/048775578.php
LOCUS MW040663 29809 bp RNA linear VRL 27-SEP-2020LOCUS MW040663 29809 bp RNA linear VRL 27-SEP-2020
LOCUS MW040663 29809 bp RNA linear VRL 27-SEP-2020 DEFINITION Severe acute respiratory syndrome coronavirus 2 isolate SARS-CoV-2/human/USA/FL-BPHL-1453/2020 ORF1ab polyprotein (ORF1ab), ORF1a polyprotein (ORF1ab), surface glycoprotein (S), ORF3a protein (ORF3a), envelope protein (E), membrane glycoprotein (M), and ORF6 protein (ORF6) genes, complete cds; ORF7a protein (ORF7a) and ORF7b (ORF7b) genes, partial cds; and ORF8 protein (ORF8), nucleocapsid phosphoprotein (N), and ORF10 protein (ORF10) genes, complete cds. ACCESSION MW040663 VERSION MW040663.1 KEYWORDS . SOURCE Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORGANISM Severe acute respiratory syndrome coronavirus 2 Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus. REFERENCE 1 (bases 1 to 29809) AUTHORS Schmedes,S. and Blanton,J. TITLE Direct Submission JOURNAL Submitted (25-SEP-2020) BPHL, FLDOH, 1217 N Pearl St, ...
https://getentry.ddbj.nig.ac.jp/getentry?database=ddbj&accession_number=MW040663.1
Recombinant SARS Coronavirus Envelope protein Envelope-301V - Creative BioMart
Purified Recombinant SARS Coronavirus Envelope protein from Creative Biomart. Recombinant SARS Coronavirus Envelope protein can be used for research.
https://www.creativebiomart.net/recombinant-sars-coronavirus-envelope-protein-507758.htm
pH-Dependent Entry of Severe Acute Respiratory Syndrome Coronavirus Is Mediated by the Spike Glycoprotein and Enhanced by...pH-Dependent Entry of Severe Acute Respiratory Syndrome Coronavirus Is Mediated by the Spike Glycoprotein and Enhanced by...
In this study, we have examined the function of the SARS-CoV S protein and the contribution of other viral membrane proteins to virus fusion and entry. We suggest that, of these gene products, the S glycoprotein is necessary and sufficient for viral gene delivery. Although the origin of SARS-CoV is unknown, recent studies have suggested that it may have been transmitted from animals to humans (6, 7, 13). During the course of the SARS-CoV epidemic, molecular evolution throughout the SARS-CoV genome was detected. In addition to mutations in several regions of SARS-CoV, specific changes that involved the deletion of a 29-nucleotide region or insertion of an 82-nucleotide region in ORF8 were observed, and it is hypothesized that these changes may have facilitated the spread of the disease (7). It is possible that SARS-CoV has arisen from recombination between different coronaviruses, although the direct antecedents of the present strain are not yet defined (15, 20, 33, 36). While SARS-CoV is not ...
https://jvi.asm.org/content/78/11/5642
Welcome to CDC stacksWelcome to CDC stacks
A real-time reverse transcription-polymerase chain reaction (RT-PCR) assay was developed to rapidly detect the severe acute respiratory syndrome-associated coronavirus (SARS-CoV). The assay, based on multiple primer and probe sets located in different regions of the SARS-CoV genome, could discriminate SARS-CoV from other human and animal coronaviruses with a potential detection limit of ...
https://stacks.cdc.gov/view/cdc/7753/Print
Binding and entering: COVID finds a new homeBinding and entering: COVID finds a new home
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged as a virus with a pathogenicity closer to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and a transmissibility similar to common cold coronaviruses (CoVs). In this review, we briefly discuss the features of the receptor-binding domain (RBD) and protease cleavage of the SARS-CoV-2 spike protein that enable SARS-CoV-2 to be a pandemic virus.
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009857
Welcome to CDC stacks | Pulmonary Tuberculosis and SARS, China - 15869 | Emerging Infectious DiseasesWelcome to CDC stacks | Pulmonary Tuberculosis and SARS, China - 15869 | Emerging Infectious Diseases
This study investigated the long-term excretion of severe acute respiratory syndrome-associated coronavirus in sputum and stool specimens from 56 infected patients. The median (range) duration of virus excretion in sputa and stools was 21 (14-52) and ...
https://stacks.cdc.gov/view/cdc/15869
Syndication StorefrontSyndication Storefront
Table 2 listed on pages 703-15 summarizes finalized data, as of June 30, 2014, from the National Notifiable Diseases Surveillance System (NNDSS) for 2013. These data will be published in more detail next year in the Summary of Notifiable Diseases - United States, 2013 (1). Because no cases were reported in the United States during 2013, the following diseases do not appear in these early release tables: anthrax; diphtheria; eastern equine encephalitis, nonneuroinvasive disease; poliovirus infection, nonparalytic; severe acute respiratory syndrome-associated coronavirus disease (SARS-CoV); smallpox; St.. ...
https://digitalmedia.hhs.gov/storefront/listMediaForTag/958?tagName=diseases
Emerging Viruses in Human Populations - Volume 13, Number 12-December 2007 - Emerging Infectious Disease journal - CDC
With increasing international travel and globalization of the worlds economies, changing climates, and altered human behavior and demographics, multiple viruses have emerged to occupy expanded ecologic niches, producing disease syndromes in parts of the world where they had never before existed. Because most emerging viral diseases in humans in the 21st century have been zoonotic, Emerging Viruses in Human Populations focuses on this group of viruses. The resulting overview is a book useful for anyone interested in a diverse group of viral agents that have recently elicited novel disease syndromes in human populations around the world. This text does an excellent job of encompassing a wide variety of contact-transmitted enzootic viruses including severe acute respiratory syndrome-associated coronavirus, Nipah and Hendra viruses, influenza virus, hantaviruses, monkeypox viruses, and vector-transmitted agents including Crimean-Congo hemorrhagic fever, dengue, West Nile, and Japanese encephalitis ...
https://wwwnc.cdc.gov/eid/article/13/12/07-0974_article
Rapid In‐Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) Using Povidone‐Iodine Oral...Rapid In‐Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) Using Povidone‐Iodine Oral...
Please send us corrections, updates, or comments. Vaccines and treatments are both extremely valuable and complementary. All practical, effective, and safe means should be used. Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. Denying the efficacy of any method increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. Treatment protocols for physicians are available from the FLCCC. ...
https://c19pvpi.com/bidra.html
Children Under 5 Could Spread Coronavirus More Than Adults- New Study - HealthTimesChildren Under 5 Could Spread Coronavirus More Than Adults- New Study - HealthTimes
CHILDREN below the age of five could be major carriers of the coronavirus as compared to adults, a new study has found.. By Michael Gwarisa According to the study Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19), which was published in JAMA Pediatrics and led by Dr. Taylor Heald-Sargent, a pediatric infectious diseases expert at the Ann and Robert H. Lurie Childrens Hospital of Chicago, children are susceptible to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but generally present with mild symptoms compared with adults.. Children drive spread of respiratory and gastrointestinal illnesses in the population, but data on children as sources of SARS-CoV-2 spread are sparse. Early reports did not find strong evidence of children as major contributors to SARS-CoV-2 spread,3 but school closures early in pandemic responses thwarted ...
https://healthtimes.co.zw/2020/08/01/children-under-5-could-spread-coronavirus-more-than-adults-new-study/
Wikipedia - Severe acute respiratory syndrome coronavirus 2 - Corona Virus Help
The first known infections from the SARS-CoV-2 strain were discovered in Wuhan, China.[7] The original source of viral transmission to humans and when the strain became pathogenic remains unclear.[32][33][34] Because many of the first individuals found to be infected by the virus were workers at the Huanan Seafood Market,[35][36] it has been suggested that the strain might have originated from the market.[34][37] However, other research indicates that visitors may have introduced the virus to the market, which then facilitated rapid expansion of the infections.[32][38]. Research into the natural reservoir of the virus strain that caused the 2002-2004 SARS outbreak has resulted in the discovery of many SARS-like bat coronaviruses, most originating in the Rhinolophus genus of horseshoe bats, and two viral nucleic acid sequences found in samples taken from Rhinolophus sinicus show a resemblance of 80% to SARS-CoV-2.[9][39][40] A third viral nucleic acid sequence from Rhinolophus affinis, collected ...
https://corona-virushelp.org/finding-an-eco-covid-19-anxiety-cure-that-works-for-you/what-is-the-corona-virus-wiki/wikipedia-severe-acute-respiratory-syndrome-coronavirus-2/
RePub, Erasmus University Repository: Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in...RePub, Erasmus University Repository: Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in...
A new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently emerged to cause a human pandemic. Although molecular diagnostic tests were rapidly developed, serologic assays are still lacking, yet urgently needed. Validated serologic assays are needed for contact tracing, identifying the viral reservoir, and epidemiologic studies. We developed serologic assays for detection of SARS-CoV-2 neutralizing, spike protein-specific, and nucleocapsid-specific antibodies. Using serum samples from patients with PCR-confirmed SARS-CoV-2 infections, other coronaviruses, or other respiratory pathogenic infections, we validated and tested various antigens in different in-house and commercial ELISAs. We demonstrated that most PCR-confirmed SARS-CoV-2-infected persons seroconverted by 2 weeks after disease onset. We found that commercial S1 IgG or IgA ELISAs were of lower specificity, and sensitivity varied between the 2 assays; the IgA ELISA showed higher sensitivity. Overall, ...
https://repub.eur.nl/pub/130532
Mechanisms of Host Defense following Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) Pulmonary Infection of Mice | The...Mechanisms of Host Defense following Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) Pulmonary Infection of Mice | The...
This study demonstrates that B6 mice can be productively infected by SARS-CoV in the bronchial and bronchiolar epithelium of the respiratory tract, and that virus is rapidly cleared through a mechanism independent of NK cells, NK-T cells, and T and B lymphocytes. Virus is able to spread to the brain at late time points when it has already been cleared by the lung, and may spread to multiple other organs. SARS-CoV induces dramatic up-regulation of a subset of inflammatory chemokines and the chemokine receptor CXCR3, but interestingly this occurs without detectable expression of classic proinflammatory and immunoregulatory cytokines and without evoking marked leukocyte infiltration of the lung. Overall, infected B6 mice do not develop overt disease, but their weight gain is slowed relative to mock-infected controls.. The work confirms our previously published finding that BALB/c mice can be productively and transiently infected in the terminal bronchioles. The susceptibility of the two strains to ...
https://www.jimmunol.org/content/173/6/4030?ijkey=8077552e352edd7958be553d675ab4d9c8045efd&keytype2=tf_ipsecsha
කොවිඩ්-19 - විකිපීඩියාකොවිඩ්-19 - විකිපීඩියා
කොවිඩ්-19 එසේත් නැත්නම් කොරෝනා වෛරස් රෝගය 2019 (ඉංග්‍රීසි: Coronavirus disease 2019, COVID-19) යනු severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) වෛරසය මගින් ඇතිකරනු ලබන බෝවන රෝගයකි.[8] මෙම රෝගය මුල්වරට චීනයේ වූහාන් නුවර දී හඳුනා ගත් අතර ඉන් අනතුරුව ලොව පුරා පැතිරගොස් 2019-20 coronavirus pandemic නමින් හැඳින්වෙන ගෝලීය වසංගතය බවට වර්ධනය විය.[9][10] සාමාන්‍ය රෝග ලක්ෂණ වනුයේ උණ (fever), කැස්ස (cough) සහ හුස්ම ගැනීමේ අපහසුව (shortness of breath) වේ. මස්පිඩු වේදනාව sputum production සහ sore throat ද ...
https://si.wikipedia.org/wiki/%E0%B6%9A%E0%B7%9C%E0%B7%80%E0%B7%92%E0%B6%A9%E0%B7%8A-19
3D View - 3V3M: Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease in Complex with N-[(1R)-2-(tert...3D View - 3V3M: Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease in Complex with N-[(1R)-2-(tert...
3V3M: Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease.
http://www.rcsb.org/pdb/explore/jmol.do?structureId=3V3M&bionumber=1
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread | Virology Journal | Full TextChloroquine is a potent inhibitor of SARS coronavirus infection and spread | Virology Journal | Full Text
Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available. We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations. Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition
https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69/figures/2
RCSB PDB - 6LO0: The co-crystal structure of Severe Acute Respiratory Syndrome Coronavirus 3C Like Protease with aldehyde M14RCSB PDB - 6LO0: The co-crystal structure of Severe Acute Respiratory Syndrome Coronavirus 3C Like Protease with aldehyde M14
As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
https://www.rcsb.org/structure/6LO0
Severe acute respiratory syndrome coronavirus 2 isolate SARS-CoV-2/hum - Nucleotide - NCBISevere acute respiratory syndrome coronavirus 2 isolate SARS-CoV-2/hum - Nucleotide - NCBI
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More... ...
https://www.ncbi.nlm.nih.gov/nuccore/MT434799.1
Severe acute respiratory syndrome coronavirus 2 isolate SARS-CoV-2/hum - Nucleotide - NCBISevere acute respiratory syndrome coronavirus 2 isolate SARS-CoV-2/hum - Nucleotide - NCBI
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More... ...
https://www.ncbi.nlm.nih.gov/nuccore/MT969437.1
Four Coronavirus Proteins to Aid the Fight Against COVID-19 - Scientist BlogFour Coronavirus Proteins to Aid the Fight Against COVID-19 - Scientist Blog
For detecting the Coronavirus as well as for developing vaccines against it the virus specific proteins are promising targets for scientists. Here we will describe some of the most important Coronavirus proteins:. SARS-CoV Spike Protein. The coronavirus spike contains three segments: a large ectodomain, a single-pass transmembrane anchor and a short intracellular tail. The ectodomain consists of a receptor-binding subunit S1 and a membrane-fusion subunit S2. During virus entry, S1 binds to a receptor on the host cell surface for viral attachment, and S2 fuses the host and viral membranes, allowing viral genomes to enter host cells.. SARS-CoV Nucleocapsid Protein. Of all the coronaviral structural proteins, the N protein is the most abundant throughout infection, both in mRNA and protein levels. Compared to the mRNA levels of other structural genes, the mRNA of the N protein is expressed three to ten times higher at 12-hour post-infection.. SARS-CoV Envelope Protein. The Envelope (E) protein is ...
https://blog.scientist.com/2020/06/04/four-coronavirus-proteins-to-aid-the-fight-against-covid-19/
SARS (Severe Acute Respiratory Syndrome) Completed Phase 2 / 3 Trials for Hydroxychloroquine (DB01611) | DrugBank OnlineSARS (Severe Acute Respiratory Syndrome) Completed Phase 2 / 3 Trials for Hydroxychloroquine (DB01611) | DrugBank Online
Also known as: Severe Acute Respiratory Syndrome (SARS) / Severe Acute Respiratory Syndrome / Respiratory Syndrome, Acute, Severe / SARS (Disease) / SARS-CoV-1 infection / SARS / Severe acute respiratory syndrome (disorder) / Severe acute respiratory syndrome NOS ...
https://go.drugbank.com/indications/DBCOND0127071/clinical_trials/DB01611?phase=2%2C3&status=completed
Severe Acute Respiratory Syndrome - AdidarwinianSevere Acute Respiratory Syndrome - Adidarwinian
MERS is caused by a virus called Middle East Respiratory Syndrome Coronavirus (MERS-CoV), which belongs to the Coronavirus family of viruses. MERS Virus belongs to the genus Betacoronavirus. Coronavirus family of viruses includes viruses that usually cause respiratory tract illnesses like the common cold in human beings, and also, these viruses cause a number of diseases in animals. Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) causes Severe Acute Respiratory Syndrome (SARS).. Continue reading → ...
http://adidarwinian.com/tag/severe-acute-respiratory-syndrome/
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) infection during late pregnancy: a report of 18 patients from Wuhan...Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) infection during late pregnancy: a report of 18 patients from Wuhan...
Compared with Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), Corona Virus Disease 2019(COVID-19) spread more rapidly and widely. The population was generally susceptible. However, reports on pregnant women infected with SARS-CoV-2 were very limited. By sharing the clinical characteristics, treatments and outcomes of 18 patients with COVID-19 during late pregnancy, we hope to provide some references for obstetric treatment and management. A total of 18 patients with COVID-19 treated at Renmin Hospital of Wuhan University were collected. The epidemiological characteristics, clinical manifestations, laboratory tests, chest CT and pregnancy outcomes were performed for analysis. 1. 18 cases of late pregnancy infected with SARS-CoV-2 pneumonia were delivered at 35 + 5 weeks to 41 weeks. According to the clinical classification of COVID-19, 1 case was mild type, 16 cases were ordinary type, and 1 case was severe type. 2. According to imaging examinations: 15 (83%) cases
https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-020-03026-3
Recombinant MERS-CoV Coronavirus Nucleocapsid Protein, Baculovirus-Insect Cells, His Tag, 40068-V08B | Sino BiologicalRecombinant MERS-CoV Coronavirus Nucleocapsid Protein, Baculovirus-Insect Cells, His Tag, 40068-V08B | Sino Biological
Recombinant MERS-CoV Coronavirus Nucleocapsid Protein (Met1-Asp413) 40068-V08B with a fusion His Tag, is expressed in Baculovirus-Insect Cells. With high purity, high biological activity, high stability, and other superior features, you can use this MERS-CoV Coronavirus Nucleocapsid protein for relevant bioassay and related research.
https://www.sinobiological.com/recombinant-proteins/mers-cov-cov-nucleocapsid-40068-v08b
Molecular modelling of S1 and S2 subunits of SARS coronavirus spike glycoprotein - Research RepositoryMolecular modelling of S1 and S2 subunits of SARS coronavirus spike glycoprotein - Research Repository
The S1 and S2 subunits of the spike glycoprotein of the coronavirus which is responsible for the severe acute respiratory syndrome (SARS) have been modelled, even though the corresponding amino acid sequences were not suitable for tertiary structure predictions with conventional homology and/or threading procedures. An indirect search for a protein structure to be used as a template for 3D modelling has been performed on the basis of the genomic organisation similarity generally exhibited by coronaviruses. The crystal structure of Clostridium botulinum neurotoxi n B appeared to be structurally adaptable to human and canine coronavirus spike protein sequences and it was successfully used to model the two subunits of SARS coronavirus spike glycoprotein. The overall shape and the surface hydrophobicity of the two subunits in the obtained models suggest the localisation of the most relevant regions for their activity. © 2003 Elsevier Inc. All rights reserved.. ...
http://repository.essex.ac.uk/14827/
Human Novel Coronavirus Spike Glycoprotein RBD (SARS-CoV-2 S RBD) IgG Antibody ELISA Kit 酱聗克疪诗刿盋 且丟揓侙基囤,释织蛄白,抑佌,ELISA kit...
2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike glycoprotein RBD; Spike Protein ...
http://www.foksnews.com/ELISA-Kit/Human-Novel-Coronavirus-Spike-Glycoprotein-RBD-
Recombinant SARS Coronavirus spike Protein, Baculovirus-Insect Cells, His Tag, 40150-V08B2 | Sino BiologicalRecombinant SARS Coronavirus spike Protein, Baculovirus-Insect Cells, His Tag, 40150-V08B2 | Sino Biological
Recombinant SARS Coronavirus spike Protein (Arg306-Phe527) RBD His Tag 40150-V08B2 with a fusion His Tag, is expressed in Baculovirus-Insect Cells. With high purity, high biological activity, high stability, and other superior features, you can use this SARS Coronavirus spike protein for relevant bioassay and related research.
https://kr.sinobiological.com/recombinant-proteins/sars-cov-spike-40150-v08b2
Recombinant SARS Coronavirus spike Protein, Baculovirus-Insect Cells, His Tag, 40150-V08B1 | Sino BiologicalRecombinant SARS Coronavirus spike Protein, Baculovirus-Insect Cells, His Tag, 40150-V08B1 | Sino Biological
Recombinant SARS Coronavirus spike Protein (Met1-Arg667) S1 Subunit His Tag 40150-V08B1 with a fusion His Tag, is expressed in Baculovirus-Insect Cells. With high purity, high biological activity, high stability, and other superior features, you can use this SARS Coronavirus spike protein for relevant bioassay and related research.
https://kr.sinobiological.com/recombinant-proteins/sars-cov-spike-40150-v08b1
Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains -...Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains -...
Severe acute respiratory syndrome coronavirus (SARS-CoV) causes a respiratory disease leading to death in 10% of the infected people. A mouse adapted SARS-CoV lacking the envelope (E) protein (rSARS-CoV-MA15-ΔE) is attenuated in vivo. To identify E protein domains and host responses that contribute to rSARS-CoV-MA15-ΔE attenuation, several mutants (rSARS-CoV-MA15-E*) containing point mutations or deletions in the amino-terminal or the carboxy-terminal regions of E protein, respectively, were generated. Amino acid substitutions in the amino terminus, or deletion of domains in the internal carboxy terminal region of E protein led to viral attenuation. Attenuated viruses induced minimal lung injury and limited neutrophil influx to the lungs but, interestingly, increased CD4+ and CD8+ T cell counts in BALB/c mice. To analyze the host responses leading to rSARS-CoV-MA15-E* attenuation, the differential gene expression elicited by the native virus and the mutant ones in infected cells was analyzed. The
https://omictools.com/a90e0f7a39b0f8151fd1e2dc293147a8-dataset
Severe Acute Respiratory Syndrome (sars) | Encyclopedia.com
Severe Acute Respiratory Syndrome (SARS) Definition Severe acute respiratory syndrome (SARS) is the first emergent and highly transmissible viral disease to appear during the twenty-first century.
https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/severe-acute-respiratory-syndrome-sars
Evaluation of organ function in patients with severe COVID-19 infections | Medicina ClínicaEvaluation of organ function in patients with severe COVID-19 infections | Medicina Clínica
Discussion. The novel coronavirus is a member of the β coronavirus type, with humans as the host. Since the first human coronavirus (HCoV) was isolated from the nasal secretions of patients with the common cold in 1965, six different strains of CoV are known to infect humans. These CoV strains include severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and the common cold viruses in individuals with strong immunity (such as 229E, OC43, NL63, and HKU1).1 This novel coronavirus, COVID-19, has more than 85% homology with the previously detected bat coronavirus (a SARS-related coronavirus species, that is, SARS coronavirus). However, there are clear differences in the genetic characteristics of COVID-19 compared with SARS-CoV and MERS-CoV.5. Through observation of the current global epidemic situation, we can demonstrate the infectivity and pathogenicity of COVID-19. To the treatment of COVID-19, the main treatment is antiviral therapy, ...
https://www.elsevier.es/es-revista-medicina-clinica-2-articulo-evaluation-organ-function-in-patients-S0025775320303390
Severe Acute Respiratory Syndrome | Profiles RNS
Taylor JK, Coleman CM, Postel S, Sisk JM, Bernbaum JG, Venkataraman T, Sundberg EJ, Frieman MB. Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference. J Virol. 2015 Dec; 89(23):11820-33 ...
https://uams-triprofiles.uams.edu/profiles/display/122061
Viral respiratory system diseases such as for example severe acute respiratory system symptoms (SARS) and Middle East...Viral respiratory system diseases such as for example severe acute respiratory system symptoms (SARS) and Middle East...
Viral respiratory system diseases such as for example severe acute respiratory system symptoms (SARS) and Middle East respiratory system symptoms (MERS) always pose a serious threat to the people. using the same sea food market. Together with the Spring Event exodus, an outbreak appeared unavoidable. This problem attracted the interest of the Chinese language Middle for Disease Control and Avoidance (CDC), who instantly released a crisis response. The World Health Organization (WHO) also responded promptly and declared the outbreak a public health emergency of international concern (PHEIC). The causative agent of the unidentified pneumonia has been confirmed as a novel coronavirus by sequencing and aetiological investigations by several independent laboratories in China. Following the isolation of the new coronavirus, it was found to be distinct both from Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus (SARS-CoV) [1,2]. Coronaviruses are ...
https://stopvivisection.info/%EF%BB%BFviral-respiratory-system-diseases-such-as-for-example-severe-acute-respiratory-system-symptoms-sars-and-middle-east-respiratory-system-symptoms-mers-always-pose-a-serious-threat-to-the-pe/
Severe acute respiratory syndrome - Simple English Wikipedia, the free encyclopediaSevere acute respiratory syndrome - Simple English Wikipedia, the free encyclopedia
Severe acute respiratory syndrome (SARS) [1] was an atypical pneumonia.[2] It started in November 2002 in Guangdong Province, in the city of Foshan, of the Peoples Republic of China. The disease was caused by the SARS coronavirus (SARS CoV), a new coronavirus. It was also a part-time STD, it can be spread through both sexual and casual contact. SARS was first reported in Asia in February 2003. Over the next few months, the illness spread to more than 24 countries in Asia, North America, South America, and Europe before the SARS global outbreak of 2003 was contained. According to the World Health Organization (WHO), a total of 8098 people worldwide became sick with SARS during the 2003 outbreak; 774 of these died. After the Chinese government suppressed news of the SARS outbreak, the disease spread rapidly, reaching Hong Kong and Vietnam in late February 2003, and then to other countries via international travellers. The last case in this outbreak occurred in June 2003. There were a total of ...
https://simple.wikipedia.org/wiki/Severe_acute_respiratory_syndrome
symptoms of a respiratory illness - Adidarwiniansymptoms of a respiratory illness - Adidarwinian
MERS is caused by a virus called Middle East Respiratory Syndrome Coronavirus (MERS-CoV), which belongs to the Coronavirus family of viruses. MERS Virus belongs to the genus Betacoronavirus. Coronavirus family of viruses includes viruses that usually cause respiratory tract illnesses like the common cold in human beings, and also, these viruses cause a number of diseases in animals. Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) causes Severe Acute Respiratory Syndrome (SARS).. Continue reading → ...
http://adidarwinian.com/tag/symptoms-of-a-respiratory-illness/
Dynamic Profiles of Cytokine/Chemokine in Severe Acute Respiratory Syndrome - Tabular View - ClinicalTrials.govDynamic Profiles of Cytokine/Chemokine in Severe Acute Respiratory Syndrome - Tabular View - ClinicalTrials.gov
Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by a novel coronavirus (SARS-CoV). The major clinical features of SARS include fever, dyspnea, lymphopenia, and a rapid progression of pulmonary infiltrates on chest radiologic images. The SARS-related deaths have resulted mainly from pulmonary complications, including progressive respiratory failure due to alveolar damage and acute respiratory distress syndrome (ARDS). Pathological changes in SARS suggest that SARS sequelae such as infiltration of PMN in lung tissue, multiple organ dysfunction and ARDS have been associated with cytokines and chemokine dysregulation. Some patients still manifested lung injury at a time when the viral load was falling also supports the immune nature of the lung damage. We therefore undertook an analysis of dynamic production of cytokine/chemokines in SARS patients with an initial normal chest radiograph in order to improve understanding of disease pathogenesis and improve patient ...
https://clinicaltrials.gov/ct2/show/record/NCT00173459
Severe acute respiratory syndrome (SARS) | Go Ask Alice!Severe acute respiratory syndrome (SARS) | Go Ask Alice!
Dear Reader,. Thanks for the props! And glad to be of service.. SARS is a serious health concern, and it can be dangerous if you come into contact with it. However, you dont necessarily need to be concerned. The media grasped onto the sensationalized story of SARS because of its rapid spread made possible by the relatively new phenomenon of extensive and frequent world travel and the fast rate of transmission. Luckily the virus was quickly isolated and contained only months after its initial out-break.. SARS, which is an acronym for Severe Acute Respiratory Syndrome, is a contagious and sometimes fatal respiratory illness that is actually a severe form of pneumonia. It is caused by a strain of the coronavirus, which is also the family of viruses that causes the common cold. SARS first appeared in China in 2002, and within six weeks had spread worldwide. Within a month and a half, 8,000 people were infected and 800 had died. SARS dramatically taught us how rapidly world travel can spread ...
http://www.goaskalice.columbia.edu/answered-questions/severe-acute-respiratory-syndrome-sars
Severe Acute Respiratory Syndrome (SARS) - Health, Disease, Quarantine, and Officials - JRank Articles
Severe acute respiratory syndrome (SARS) is the first emergent and highly transmissible viral disease to appear during the twenty-first century. Patients with SARS develop flu-like fever, headache, malaise, dry cough and other breathing difficulties. Many patients develop pneumonia, and in 5-10% of cases, the pneumonia and other complications are severe enough to cause death. SARS is caused by a virus that is transmitted usually from person to person-predominantly by the aerosolized droplets of virus infected material.. SARS cases provided a test of recent reforms in International Health Regulations designed to increase surveillance and reporting of infectious diseases-and to enhance cooperation in preventing the international spread of disease. Although not an act of bioterrorism, because the very same epidemiologic principles and isolation protocols might be used to both initially determine and initially respond to an act of bioterrorism, intelligence and public heath officials closely ...
http://science.jrank.org/pages/6085/Severe-Acute-Respiratory-Syndrome-SARS.html
SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness : a systematic review...SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness : a systematic review...
Background Viral load kinetics and duration of viral shedding are important determinants for disease transmission. We aimed to characterise viral load dynamics, duration of viral RNA shedding, and viable virus shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in various body fluids, and to compare SARS-CoV-2, SARS-CoV, and Middle East respiratory syndrome coronavirus (MERS-CoV) viral dynamics. Methods In this systematic review and meta-analysis, we searched databases, including MEDLINE, Embase, Europe PubMed Central, medRxiv, and bioRxiv, and the grey literature, for research articles published between Jan 1, 2003, and June 6, 2020. We included case series (with five or more participants), cohort studies, and randomised controlled trials that reported SARS-CoV-2, SARS-CoV, or MERS-CoV infection, and reported viral load kinetics, duration of viral shedding, or viable virus. Two authors independently extracted data from published studies, or contacted authors to request ...
https://research-repository.st-andrews.ac.uk/handle/10023/21023
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) - anatomic pathology...Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) - anatomic pathology...
The world is currently witnessing a major devastating pandemic of Coronavirus disease-2019 (COVID-19). This disease is caused by a novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). It primarily affects the respiratory tract and particularly the lungs. The virus enters the cell by attaching its spike-like surface projections to the angiotensin-converting enzyme-2 (ACE-2) expressed in various tissues. Though the majority of symptomatic patients have mild flu-like symptoms, a significant minority develop severe lung injury with acute respiratory distress syndrome (ARDS), leading to considerable morbidity and mortality. Elderly patients with previous cardiovascular comorbidities are particularly susceptible to severe clinical manifestations. Currently, our limited knowledge of the pathologic findings is based on post-mortem biopsies, a few limited autopsies, and very few complete autopsies. From these reports, we know that the virus can be found in various organs but the
https://diagnosticpathology.biomedcentral.com/articles/10.1186/s13000-020-01017-8
Keep Your Employees Safe from the MERS VirusKeep Your Employees Safe from the MERS Virus
As more companies send employees on global travel, its important for safety and health managers to have a proper infection control system. If an employee contracts an infectious disease, the possibility of spreading it throughout the company could develop into a serious problem for the employer.. For instance, between November 2002 and July 2003, an outbreak of a terrible viral respiratory illness caused by a coronavirus occurred in South China. This disease, Severe Acute Respiratory Syndrome coronavirus (SARS-CoV), was on the verge of becoming a pandemic. According to the World Health Organization (WHO), there were 8,098 cases and 774 deaths worldwide. In general, SARS begins with a high fever and can lead to other symptoms such as headaches, an overall feeling of discomfort and body aches. The illness spread to more than two dozen countries before the 2003 outbreak was contained.. In April 2012, a new coronavirus emerged in the Middle East: Middle East Respiratory Syndrome Coronavirus ...
https://www.shrm.org/resourcesandtools/hr-topics/risk-management/pages/employees-safe-mers-virus.aspx
SARS (Severe acute respiratory syndrome) - Your.MD
Severe acute respiratory syndrome (SARS) is a highly contagious, serious and potentially life-threatening form of pneumonia. (SARS (Severe syndrome))
https://www.your.md/condition/sars
Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province, China, January-March 2020:...
We have systematically described the clinical characteristics of 96 patients with covid-19 and described the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) loads and disease progression in 3497 samples of multiple types, revealing the interaction between SARS-CoV-2 replication and clearance by host defence mechanisms. The median duration of virus in respiratory samples was 18 days, which was consistent with the median duration of 20 days for Middle East respiratory syndrome (MERS).12 Peak viral shedding in respiratory specimens of patients with severe acute respiratory syndrome (SARS) occurred after about 10 to 12 days from symptom onset,1314 which is similar to the peak observed for SARS-CoV-2 in our study. Consistent with earlier reports of SARS-CoV-2,15 we found differences in the viral load in patients with different disease severities, those with severe disease showing a significantly higher viral load than those with mild disease, which suggests that viral ...
https://www.bmj.com/content/369/bmj.m1443?ijkey=b73bd2824a5427ecceb10427b47be5fcb95a6eef&keytype2=tf_ipsecsha
Preliminary Clinical Description of Severe Acute Respiratory SyndromePreliminary Clinical Description of Severe Acute Respiratory Syndrome
On March 21, 2003, this report was posted on the MMWR website (http://www.cdc.gov/mmwr). Severe acute respiratory syndrome (SARS) is a condition of unknown etiology that has been described in patients in Asia, North America, and Europe. This report summarizes the clinical description of patients with SARS based on information collected since mid-February 2003 by the World Health Organization (WHO), Health Canada, and CDC in collaboration with health authorities and clinicians in Hong Kong, Taiwan, Bangkok, Singapore, the United Kingdom, Slovenia, Canada, and the United States. This information is preliminary and limited by the broad and necessarily nonspecific case definition. As of March 21, 2003, the majority of patients identified as having SARS have been adults aged 25--70 years who were previously healthy. Few suspected cases of SARS have been reported among children aged ,15 years. The incubation period for SARS is typically 2--7 days; however, isolated reports have suggested an incubation ...
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5212a5.htm
Nitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19 - Full Text View - ClinicalTrials.govNitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19 - Full Text View - ClinicalTrials.gov
Severe acute respiratory syndrome (SARS-CoV-2) due to novel Coronavirus (2019-nCoV) related infection (COVID-19) is characterized by severe ventilation perfusion mismatch leading to refractory hypoxemia. To date, there is no specific treatment available for 2019-nCoV. Nitric oxide is a selective pulmonary vasodilator gas used as a rescue therapy in refractory hypoxemia due to acute respiratory distress syndrome (ARDS). In has also shown in-vitro and clinical evidence that inhaled nitric oxide gas (iNO) has antiviral activity against other strains of coronavirus.. The primary aim of this study is to determine whether inhaled NO improves oxygenation in patients with hypoxic SARS-CoV2.. This is a multicenter randomized controlled trial with 1:1 individual allocation. Patients will be blinded to the treatment.. Intubated patients admitted to the intensive care unit with confirmed SARS-CoV-2 infection and severe hypoxemia will be randomized to receive inhalation of NO (treatment group) or not ...
https://clinicaltrials.gov/ct2/show/NCT04306393?term=nitric+oxide+coronavirus&draw=2&rank=1
Should Remdesivir Be Used for the Treatment of Patients With COVID-19? by Amir Qaseem, Jennifer Yost et al.Should Remdesivir Be Used for the Treatment of Patients With COVID-19? by Amir Qaseem, Jennifer Yost et al.
Remdesivir, a broad-spectrum antiviral agent administered intravenously, was developed and studied as a potential treatment for Ebola virus disease and Marburg virus infection. In vitro and in vivo preclinical studies found antiviral activity for remdesivir against corona-like viruses, including Middle East respiratory syndrome coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV-1), the circulating human coronaviruses HCoV-OC42 and HCoV-229E, and SARS-CoV-2. Currently, the effectiveness of remdesivir is being tested as a treatment for patients infected with SARS-CoV-2 (COVID-19) and has been authorized for emergency use for treating COVID-19, by the U.S. Food and Drug Administration in the United States, and in other countries. The American College of Physicians (ACP) Scientific Medical Policy Committee (SMPC) based these rapid and living practice points on a systematic evidence review conducted by the U.S. Department of Veterans Affairs (VA) Evidence Synthesis Program in Minneapolis,
https://escholarship.umassmed.edu/covid19/125/
WHO | WHO Global Conference on Severe Acute Respiratory Syndrome (SARS)WHO | WHO Global Conference on Severe Acute Respiratory Syndrome (SARS)
The WHO Global Conference on Severe Acute Respiratory Syndrome (SARS), was held in the Sunway Lagoon Resort Hotel, Persiaran Lagoon, Bandar Sunway, 46150, Petaling Jaya, Selangor Darul Ehsan, Kuala Lumpur, Malaysia on 17-18 June 2003.. ...
http://www.who.int/csr/sars/conference/june_2003/en/
PRIME PubMed | Adolescent twin sisters with severe acute respiratory syndrome (SARS)PRIME PubMed | Adolescent twin sisters with severe acute respiratory syndrome (SARS)
PubMed journal article: Adolescent twin sisters with severe acute respiratory syndrome (SARS). Download Prime PubMed App to iPhone, iPad, or Android
https://www.unboundmedicine.com/medline/citation/14754985/Adolescent_twin_sisters_with_severe_acute_respiratory_syndrome__SARS__
Search Results for Australia Online Pharmacy ⭐ www.HealthMeds.online ⭐ Kamagra Buy Australia - Kamagra Cost Australia - UC...Search Results for Australia Online Pharmacy ⭐ www.HealthMeds.online ⭐ Kamagra Buy Australia - Kamagra Cost Australia - UC...
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a grave threat to public health and the global economy. SARS-CoV-2 is closely related to the more lethal but less transmissible coronaviruses SARS-CoV-1 and Middle East respiratory syndrome coronavirus (MERS-CoV). Here, we have carried out comparative viral-human protein-protein interaction and viral protein ...
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The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a grave threat to public health and the global economy. SARS-CoV-2 is closely related to the more lethal but less transmissible coronaviruses SARS-CoV-1 and Middle East respiratory syndrome coronavirus (MERS-CoV). Here, we have carried out comparative viral-human protein-protein interaction and viral protein ...
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Severe Acute Respiratory Syndrome related to Coronavirus-2 (SARS-CoV-2), coronavirus disease-2019 (COVID-19) may cause severe...Severe Acute Respiratory Syndrome related to Coronavirus-2 (SARS-CoV-2), coronavirus disease-2019 (COVID-19) may cause severe...
Severe Acute Respiratory Syndrome related to Coronavirus-2 (SARS-CoV-2), coronavirus disease-2019 (COVID-19) may cause severe illness in 20% of individuals. JAK inhibitors, corticosteroids, immunoglobulins, heparins, angiotensin-converting enzyme agonists and statins in severe COVID-19. In severe instances, COVID-19 with MAS happens in individuals with ARDS, sepsis and septic shock, and ultimately, multiorgan failure and death, linked to sustained IL-6 and IL-1 elevation. While slight medical forms only require symptomatic management, in moderate-severe forms in-hospital monitoring with general actions plus antivirus and/or HCQ administration is necessary. However, in more severe and life-threating instances, a high intensity pharmacological treatment is recommended. The pathogenesis of the acute pulmonary injury related to COVID-19 is very similar that happen in additional disorders that induce high hyperinflammatory state with a launch of high amounts of pro-inflammatory cytokine primarily, ...
http://aacc2020.com/%EF%BB%BFsevere-acute-respiratory-syndrome-related-to-coronavirus-2-sars-cov-2-coronavirus-disease-2019-covid-19-may-cause-severe-illness-in-20-of-individuals/
Severe acute respiratory syndromeSevere acute respiratory syndrome
Severe acute respiratory syndrome (SARS) was caused by a previously unrecognized animal coronavirus that exploited opportunities provided by wet markets in southern China to adapt to become a virus readily transmissible between humans. Hospitals and international travel proved to be amplifiers t …
https://pubmed.ncbi.nlm.nih.gov/15577937/
Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS...Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS...
Hong Kong Med J 2009;15(Suppl 2):S33-6 Mouse studies of SARS coronavirus-specific immune responses to recombinant replication-defective adenovirus expressing SARS coronavirus N protein FWY Sin, SCS Ch
https://www.hkmj.org/abstracts/v15n1s2/33.htm
Coronavirus Nucleocapsid Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents | Sino BiologicalCoronavirus Nucleocapsid Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents | Sino Biological
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Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service [13] | ScholarBank@NUSOutbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service [13] | [email protected]
Liu, E.H., Koh, K.-F., Chen, F.-G. (2004-06). Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service [13]. Anesthesiology 100 (6) : 1629-1630. [email protected] Repository ...
http://scholarbank.nus.edu.sg/handle/10635/132947
Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service [13] | ScholarBank@NUSOutbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service [13] | [email protected]
Liu, E.H.,Koh, K.-F.,Chen, F.-G. (2004). Outbreak of severe acute respiratory syndrome in Singapore and modifications in the anesthesia service [13]. Anesthesiology 100 (6) : 1629-1630. [email protected] Repository ...
http://scholarbank.nus.edu.sg/handle/10635/30888
The global outbreak caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been declared a pandemic by...
The global outbreak caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been declared a pandemic by the WHO. As the number of imported SARS-CoV-2 cases is on the rise in Brazil, we use incidence and historical air travel data to estimate the most important routes of importation into the country.
https://www.immunology.ox.ac.uk/publications/1097323
Brief Report: Incubation Period Duration and Severity of Clinical Disease Following Severe Acute Respiratory Syndrome...Brief Report: Incubation Period Duration and Severity of Clinical Disease Following Severe Acute Respiratory Syndrome...
We estimated the incubation period of severe acute respiratory syndrome based on a subset of patients with available data on exposure periods and a separate subset of patients in a putative common source outbreak, and we found associations between shorter incubation period and greater severity in both groups after adjusting for potential confounders ...
https://midasnetwork.us/papers/brief-report-incubation-period-duration-and-severity-of-clinical-disease-following-severe-acute-respiratory-syndrome-coronavirus-infection/
Real-time polymerase chain reaction for detecting SARS coronavirus, Beijing, 2003 | Academic CommonsReal-time polymerase chain reaction for detecting SARS coronavirus, Beijing, 2003 | Academic Commons
During the 2003 severe acute respiratory syndrome (SARS) outbreak, a real-time quantitative polymerase chain reaction, which targets the nucleocapsid gene at the 3′-end of the viral genome, was established to detect and identify the SARS-associated coronavirus. We describe the use of this assay to screen |700 clinical samples.
https://academiccommons.columbia.edu/doi/10.7916/D8XP79PN
Covid 19 Research Clinical Trials by Shray AlagCovid 19 Research Clinical Trials by Shray Alag
The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has been discovered recently in December 2019 from wuhan city in China to spread in more than 40 countries allover the world. This disease has gain the attention of all nations after it has been stated as a pandemic by the World Health Organization (WHO) in March 12, 2020. Currently no treatment has been proved to be efficient in the treatment of infected patients by COVID-19. Natural honey has been demonstrated as potent antimicrobial in many research investigations and has been considered a good alternative for antiviral drugs for the treatment of some viral infections. The investigators aim to study the efficacy of natural honey in the treatment of COVID-19 patients in this randomized , multicenter, controlled trial, comparing honey in one arm to standard care in the other arm. ...
http://covidresearchtrials.com/09262020/output/covid/drug/drug2165.html
Scientists Identify SARS Receptor - Scientific AmericanScientists Identify SARS Receptor - Scientific American
Severe acute respiratory syndrome (SARS) originated in southern China in November 2002, and soon spread to people on six continents, killing nearly 800 people all told. For the first time, researchers have identified a crucial SARS receptor in vivo that helps explain how and why SARS infection causes lung failure. The findings should help researchers treat other diseases that compromise lung function. Previous research using cell lines had identified ACE2, a protein involved in regulating blood pressure, as a potential SARS receptor. Now Josef Penninger of the Institute of Molecular Biotechnology (IMBA) in Vienna, Austria, and his colleagues have tested the hypothesis in mice. In a paper published online yesterday by Nature Medicine, they report that SARS infection, and specifically the SARS protein known as Spike, reduces ACE2 expression. As a result, blood vessels in the lungs become damaged and the lung becomes flooded as a result. In a second paper published in the current issue of the ...
https://www.scientificamerican.com/article/scientists-identify-sars/
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection | CMAJSafety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection | CMAJ
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly around the globe in recent months. With deaths from its associated disease, coronavirus disease 2019 (COVID-19), projected to reach into the millions and a vaccine unlikely in the near term, the search is on for existing drugs that might prevent COVID-19 or improve outcomes for patients who have COVID-19. Chloroquine and its derivative hydroxychloroquine, which have been used for decades in the treatment and prevention of malaria as well as chronic inflammatory diseases such as rheumatoid arthritis and systemic lupus erythematosus, have received much attention as potential therapies.. Optimism for repurposing these drugs stems from 2 lines of evidence: inhibition of Coronaviridae (including SARS and SARS-CoV-2) in vitro1-3 and preliminary but contradictory clinical data from studies conducted in China and France.4-8 Of these, an open-label nonrandomized study by Gautret and colleagues5 that involved treatment using ...
https://www.cmaj.ca/content/192/17/E450.long
Search | COVID-19Search | COVID-19
Quinacrine (Qx), a molecule used as an antimalarial, has shown anticancer, antiprion, and antiviral activity. The most relevant antiviral activities of Qx are related to its ability to raise pH in acidic organelles, diminishing viral enzymatic activity for viral cell entry, and its ability to bind to viral DNA and RNA. Moreover, Qx has been used as an immunomodulator in cutaneous lupus erythematosus and various rheumatological diseases, by inhibiting phospholipase A2 modulating the Th1/Th2 response. The aim of this study was to evaluate the potential antiviral effect of Qx against denominated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Vero E6 cells. The cytotoxicity of Qx in Vero E6 cells was determined by the MTT assay. Afterwards, Vero E6 cells were infected with SARS-CoV-2 at different multiplicities of infections (MOIs) of 0.1 and 0.01 in the presence of Qx (0-30 µM) to determinate the half maximal effective concentration (EC50). After 48 h, the effect of Qx ...
https://search.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/?lang=en&q=mh:%22Cell%20Line%22
2002-2004 SARS outbreak2002-2004 SARS outbreak
The virus was officially named the SARS virus. On 17 April, the first confirmed case of SARS from India was reported. On 19 ... The 2002-2004 outbreak of SARS, caused by severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), infected over ... SARS section SARS: An Open Scar Archived 22 November 2005 at the Wayback Machine SARS: Timeline of an Outbreak Archived 26 ... The virus soon spread to nearby hospitals. In February 2003, Liu Jianlun became Hong Kong's SARS index patient. He had come to ...
https://en.wikipedia.org/wiki/2002–2004_SARS_outbreak
Arnold MontoArnold Monto
Anstett, Patricia (3 June 2003). "SARS has virus hunter very busy". Knight-Ridder Newspapers. Detroit Free Press. Retrieved 17 ... Monto fulfilled his national service commitment in the Virus Diseases Section of the Middle America Research Unit, part of the ... Monto, AS; Olazabal, F (1966). "Asian influenza in the Panama Canal zone: isolation of a virus variant and protective effect of ... While there, he began his career-long interest in respiratory illnesses; confirming that the same viruses causing illnesses in ...
https://en.wikipedia.org/wiki/Arnold_Monto
Joanna TseJoanna Tse
"Volunteer Sars doctor dies of virus". South China Morning Post. 2003-05-14. Retrieved 2018-03-07. "舊時香港". www.facebook.com. ... In March 2003, SARS broke out in Hong Kong. Tuen Mun Hospital received three SARS patients, but there were not enough ... Tse volunteered to work in the SARS ward. She and a male nurse, Lau Wing-Kai, had intubated patients with terminal SARS, and ... Of the six medical personnel who died of SARS, five were awarded the silver medal; Tse was the only gold medal recipient as ...
https://en.wikipedia.org/wiki/Joanna_Tse
Field epidemiologyField epidemiology
SARS, Nipah virus, and avian influenza). Many residents have also worked to reduce the burden of non-communicable diseases, ...
https://en.wikipedia.org/wiki/Field_epidemiology
RanpirnaseRanpirnase
"Tamir Reports Positive Effect Against SARS Virus". Darzynkiewicz Z, Carter SP, Mikulski SM, Ardelt WJ, Shogen K (May 1988). " ...
https://en.wikipedia.org/wiki/Ranpirnase
SARS-CoV-1SARS-CoV-1
WHO press release identifying and naming the SARS virus The SARS virus genetic map Science special on the SARS virus (free ... macaques infected with the virus developed the same symptoms as human SARS patients. A virus very similar to SARS was ... In 2005, two studies identified a number of SARS-like coronaviruses in Chinese bats. Although the bat SARS virus did not ... SARS-CoV primarily infects epithelial cells within the lung. The virus is capable of entering macrophages and dendritic cells ...
https://en.wikipedia.org/wiki/SARS-CoV-1
List of University of Peradeniya peopleList of University of Peradeniya people
SARS) virus; proposed the Cytokine storm theory of avian influenza Veerasingham Dhuruvasangary - soil researcher; development ... "Malik Peiris on Containing SARS and Watching for What's Next". Sciencewatch.com. 2008. Retrieved 13 June 2010. "Monsoon Journal ...
https://en.wikipedia.org/wiki/List_of_University_of_Peradeniya_people
Reporter virus particlesReporter virus particles
"Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses". Journal of Experimental Medicine. ... Reporter virus particles (RVPs) are replication-incompetent virus particles engineered to express one or more reporter genes ... Alternatively, for structurally complex viruses such dengue and Zika viruses, RVPs are engineered to be antigenically identical ... "Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 Spike protein for neutralization assays". Viruses. ...
https://en.wikipedia.org/wiki/Reporter_virus_particles
Koch-Pasteur rivalryKoch-Pasteur rivalry
2003). "Aetiology: Koch's postulates fulfilled for SARS virus". Nature. 423 (6937): 240. Bibcode:2003Natur.423..240F. doi: ... as in the identification of HIV-1 as the cause of AIDS or the identification of SARS coronavirus as the cause of SARS. Germ ...
https://en.wikipedia.org/wiki/Koch–Pasteur_rivalry
2012 Middle East respiratory syndrome outbreak2012 Middle East respiratory syndrome outbreak
"Death toll from new SARS-like virus climbs to 9". CNN. Retrieved 13 March 2013. "Saudi Arabia: 7 Cases of SARS-like Virus Seen ... "New SARS-Linked Virus Kills Man in France". Express. Associated Press. 29 May 2013. "Middle East respiratory syndrome ... Lu, Guangwen; Liu, Di (2012). "SARS-like virus in the Middle East: A truly bat-related coronavirus causing human diseases". ... James Gallagher (13 February 2013). "Coronavirus: Signs the new Sars-like virus can spread between people". BBC News. Retrieved ...
https://en.wikipedia.org/wiki/2012_Middle_East_respiratory_syndrome_outbreak
Noguchi Memorial Institute for Medical ResearchNoguchi Memorial Institute for Medical Research
"Ghanaian Scientists Successfully Sequence SARS-COV-2 Virus Genomes". Trial Site News. 2020-04-15. Retrieved 2020-04-26. " ...
https://en.wikipedia.org/wiki/Noguchi_Memorial_Institute_for_Medical_Research
Timeline of the COVID-19 pandemic in February 2020Timeline of the COVID-19 pandemic in February 2020
Additionally, the virus itself is named SARS-CoV-2. WHO Situation Report 23: Hong Kong confirmed one more case, bringing the ... This article documents the chronology and epidemiology of SARS-CoV-2 in February 2020, the virus which causes the coronavirus ... SARS-CoV-2 was detected for the first time in tears and conjunctival secretions (pink eye) of a patient. This was only detected ... "New virus cases in UK, Germany, Italy put Europe total at 31". AP NEWS. 6 February 2020. Archived from the original on 6 ...
https://en.wikipedia.org/wiki/Timeline_of_the_COVID-19_pandemic_in_February_2020
List of Italian inventions and discoveriesList of Italian inventions and discoveries
SARS virus, an infectious disease discovered by Carlo Urbani; having been infected, he didn't live long enough to see how ... The virus] could be counteracted by the product studied by the Italian company Okairos. Much of the merit of the discovery goes ... HIV Virus (co-discovered): the French Luc Montagnier and the Italian American Robert Charles Gallo (US-born) are credited with ... Oncovirus, type of virus capable of causing cancers. The experiments led by Italian-American Renato Dulbecco and his group ...
https://en.wikipedia.org/wiki/List_of_Italian_inventions_and_discoveries
Timeline of the COVID-19 pandemic in 2019Timeline of the COVID-19 pandemic in 2019
"Virus origin / Origins of the SARS-CoV-2 virus". www.who.int. "Intelligence report warned of coronavirus crisis as early as ... "China investigates SARS-like virus as dozens struck by pneumonia". Deutsche Welle. 31 December 2019. Archived from the original ... This article documents the chronology and epidemiology of SARS-CoV-2 in 2019, the virus that causes coronavirus disease 2019 ( ... The report added weight to calls for a broader probe into the theory that the COVID-19 virus could have escaped from a ...
https://en.wikipedia.org/wiki/Timeline_of_the_COVID-19_pandemic_in_2019
COVID-19 pandemic in Hong KongCOVID-19 pandemic in Hong Kong
Cheng, Kris (22 January 2020). "First case of SARS-like virus in Hong Kong". Hong Kong Free Press. Retrieved 28 May 2021. Klar ... SARS-CoV-2). The virus was first confirmed to have spread to Hong Kong on 23 January 2020. Confirmed cases were generally ... was taken to prevent the spread of a variant of the SARS-CoV-2 virus that had first been detectected in the United Kingdom and ... SARS) Portals: COVID-19 Hong Kong Medicine Viruses Ritchie, Hannah; Mathieu, Edouard; Rodés-Guirao, Lucas; Appel, Cameron; ...
https://en.wikipedia.org/wiki/COVID-19_pandemic_in_Hong_Kong
MERSMERS
SARS), and it has been referred to as Saudi Arabia's SARS-like virus. The first person, in June 2012, had a fever, cough, ... In the SARS outbreak the virus was not cultured from people after the resolution of their symptoms. It is believed that the ... Lu G, Liu D (November 2012). "SARS-like virus in the Middle East: a truly bat-related coronavirus causing human diseases". ... Lu, Guangwen; Liu, Di (2012). "SARS-like virus in the Middle East: A truly bat-related coronavirus causing human diseases". ...
https://en.wikipedia.org/wiki/MERS
Wastewater-based epidemiologyWastewater-based epidemiology
A group of Chinese scientists published the first WBE study on SARS-CoV-2 in 2020. They assessed whether the virus was present ... "Status of environmental surveillance for SARS-CoV-2 virus" (PDF). World Health Organisation. 5 August 2020. Retrieved 6 August ... The first US SARS-CoV-2 study came from Boston. It reported a far higher rate of infection than had been estimated from ... Wastewater-based epidemiology has also been adapted to measure the load of pathogens such as SARS-CoV-2 in a community. It ...
https://en.wikipedia.org/wiki/Wastewater-based_epidemiology
Timeline of the COVID-19 pandemic in January 2020Timeline of the COVID-19 pandemic in January 2020
"China investigates SARS-like virus as dozens struck by pneumonia". Deutsche Welle. 31 December 2019. Archived from the original ... The gene sequencing data of the isolated 2019-nCoV, a virus from the same family as the SARS coronavirus, was posted on ... This article documents the chronology and epidemiology of SARS-CoV-2 in January 2020, the virus which causes the coronavirus ... The outbreak has revived memories of the SARS virus when the local Chinese officials initially withheld information about the ...
https://en.wikipedia.org/wiki/Timeline_of_the_COVID-19_pandemic_in_January_2020
COVID-19 surveillanceCOVID-19 surveillance
"Status of environmental surveillance for SARS-CoV-2 virus" (PDF). World Health Organisation. 5 August 2020. Retrieved 6 August ... "Israel's Virus Surveillance Tool Tests Its Democratic Norms". Voice of America. 1 January 2021. Retrieved 10 March 2021. " ... "a suspect case for whom testing for the COVID-19 virus is inconclusive" OR "a suspect case for whom testing could not be ... and in March 2020 was ordered by emergency decree to track and notify people exposed to the virus. The decree was replaced by ...
https://en.wikipedia.org/wiki/COVID-19_surveillance
Achmad YuriantoAchmad Yurianto
"Pejabat Kemenkes Sebut Virus Corona Tak Seganas SARS dan MERS". detikHealth (in Indonesian). Archived from the original on 11 ... "Kemenkes: Tidak Ada Virus Corona di Indonesia". detikHealth (in Indonesian). Archived from the original on 22 June 2021. ... "Menkes Lantik Jubir Virus Corona Covid-19 Achmad Yurianto Jadi Dirjen P2P Kemenkes". detikHealth (in Indonesian). Archived from ... Yurianto initially denied the existence of the virus in Indonesia, stating that the COVID-19 "was relatively tame in comparison ...
https://en.wikipedia.org/wiki/Achmad_Yurianto
SARS WarsSARS Wars
He then goes mad and infects himself with the SARS virus. However, that part of the script was rewritten so that he was simply ... However, far away in Africa, there has been an outbreak of a mutant Type 4 strain of the SARS virus, which causes sufferers to ... The story involves people who are infected with a fictional Type 4 strain of the SARS virus and turned into zombies. The ... Thailand's leading health official, Public Health Minister Ratsuda, declares Thailand free of the SARS virus and that ...
https://en.wikipedia.org/wiki/SARS_Wars
CoVLPCoVLP
"Covifenz (virus-like particles (VLP) of SARS-CoV-2 spike protein)". Health Canada. 24 February 2022. Retrieved 31 May 2022. ... It uses recombinant spike proteins derived from SARS-CoV-2. The virus-like particles are produced by creating a bacterium ... CoVLP is an example of a virus-like particle vaccine, consisting of a molecular complex which closely resembles a virus, but is ... The plants take up the bacteria virus-derived genetic material, producing in its leaves the virus-like particles, which are ...
https://en.wikipedia.org/wiki/CoVLP
Cas3Cas3
"CRISPR-Cas3-based diagnostics for SARS-CoV-2 and influenza virus". iScience. 25 (2): 103830. Bibcode:2022iSci...25j3830Y. doi: ...
https://en.wikipedia.org/wiki/Cas3
COVID-19 vaccination in the United KingdomCOVID-19 vaccination in the United Kingdom
"COVID-19 (SARS-CoV-2): information about the new virus variant". Gov.uk. Public Health England. 20 December 2020. Retrieved 21 ... New guidance for allergy sufferers, antibody tests, new variants of SARS-CoV-2 (B.1.1.7 and B.1.617) and the use of the ... In response to the SARS-CoV-2 Omicron variant, third vaccine doses were made available to all adults in December 2021. The UK's ... "COVID-19 -- SARS-CoV-2". Immunisation against infectious disease (PDF). UK Health Security Agency. 5 September 2022. Retrieved ...
https://en.wikipedia.org/wiki/COVID-19_vaccination_in_the_United_Kingdom
Timeline of the COVID-19 pandemic in VietnamTimeline of the COVID-19 pandemic in Vietnam
"SARS-CoV-2 virus variant A.23.1 first detected in Vietnam". VOV.VN. "Gần 400 ca nCoV, dịch xuất hiện thêm ở Tân Sơn Nhất" (in ... Nga, Lê (3 February 2020). "Ca thứ 8 mắc virus corona ở Việt Nam" [Case 8 infected with corona virus in Vietnam]. VnExpress (in ... Nga, Lê (2 February 2020). "Ca thứ 7 ở Việt Nam nhiễm virus corona" [Case 7 in Vietnam with corona virus]. VnExpress (in ... Lê, Chi (4 February 2020). "Ca thứ 9 ở Việt Nam nhiễm virus corona" [Case 9 in Vietnam with corona virus]. VnExpress (in ...
https://en.wikipedia.org/wiki/Timeline_of_the_COVID-19_pandemic_in_Vietnam
2020 in the United Kingdom2020 in the United Kingdom
"COVID-19 (SARS-CoV-2): information about the new virus variant". Gov.uk. Public Health England. 20 December 2020. Retrieved 21 ... 27 July COVID-19 in the UK: The UK's Chief Veterinary Officer confirms that SARS-CoV-2, the virus responsible for COVID-19, has ... Control the virus. Save lives", while Scotland, Wales and Northern Ireland are sticking with "stay at home". A new alert scale ... COVID-19 in the UK: The number of people who died in hospital with SARS-CoV-2 infections in the UK passes 10,000, after a daily ...
https://en.wikipedia.org/wiki/2020_in_the_United_Kingdom
University of PeradeniyaUniversity of Peradeniya
Malik Peiris; discoverer of severe acute respiratory syndrome (SARS) virus, Prof. Saman Warnakulasuriya ; OBE- Emeritus ... "Malik Peiris on Containing SARS and Watching for What's Next". Sciencewatch. 2007. Retrieved 24 May 2010. "Janaka rejects ...
https://en.wikipedia.org/wiki/University_of_Peradeniya
Molecular diagnosticsMolecular diagnostics
... or specific strains such as H1N1 virus or SARS-CoV-2. Genetic identification can be swift; for example a loop-mediated ... Molecular diagnostics are used to identify infectious diseases such as chlamydia, influenza virus and tuberculosis; ... "RT-PCR/electrospray ionization mass spectrometry approach in detection and characterization of influenza viruses". Expert ...
https://en.wikipedia.org/wiki/Molecular_diagnostics
Alan ChristoffelsAlan Christoffels
Spotlight, Kathryn Cleary for (April 14, 2020). "The Genetic Fingerprint: How scientists unlocked SA's SARS-CoV-2 virus". Daily ... the virus that causes COVID-19, found in South Africa. His recent work features conducting research on scaling up disease ... of scientists at his lab based in South African National Bioinformatics Institute presented the first genome sequence of SARS- ...
https://en.wikipedia.org/wiki/Alan_Christoffels
Bat SARS-like coronavirus WIV1Bat SARS-like coronavirus WIV1
SARS-related coronavirus, Zoonoses, Bat virome, Infraspecific virus taxa, All stub articles, Virus stubs). ... Naik, Gautam (2013-10-30). "Study: Bat-to-Human Leap Likely for SARS-Like Virus - WSJ.com". Wall Street Journal. Online.wsj.com ... Bat SARS-like coronavirus WIV1 (Bat SL-CoV-WIV1), also sometimes called SARS-like coronavirus WIV1, is a strain of severe acute ... 2015). "Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from ...
https://en.wikipedia.org/wiki/Bat_SARS-like_coronavirus_WIV1
Yee-Sin LeoYee-Sin Leo
She has been in charge of Singapore's response to several outbreaks, including Nipah, SARS and COVID-19. In 2020, she was ... She has led the country through Middle East respiratory syndrome (MERS), Influenza A virus subtype H7N9 (bird flu) and Dengue ... Leo said that her experiences dealing with the struggles of severe acute respiratory syndrome (SARS) had served her in good ... Her first frontline experience with infectious diseases were when the Nipah virus infected Singapore in 1999. In 2002 Leo was ...
https://en.wikipedia.org/wiki/Yee-Sin_Leo
Human-to-human transmissionHuman-to-human transmission
Cook, Nigel (2013). "10.1 Introduction; the role of fomites in the virus transmission". Viruses in Food and Water: Risks, ... aka French pox SARS-CoV-2 Chowell, Gerardo; Blumberg, Seth; Simonsen, Lone; Miller, Mark A.; Viboud, Cécile (2014). " ... In these cases, the basic reproduction number of the virus, which is the average number of additional people that a single case ... A 2007 study showed that influenza virus was still active on stainless steel 24 hours after contamination. Though on hands it ...
https://en.wikipedia.org/wiki/Human-to-human_transmission
2022 Shanghai COVID-19 outbreak2022 Shanghai COVID-19 outbreak
The Chinese government's response since then has been to pursue a zero-COVID strategy, aiming to eliminate the virus altogether ... However, the increased transmissibility of the SARS-CoV-2 Omicron variant that emerged in late 2021 has posed challenges. Since ...
https://en.wikipedia.org/wiki/2022_Shanghai_COVID-19_outbreak
Coronavirus nucleocapsid proteinCoronavirus nucleocapsid protein
In SARS-CoV, the causative agent of SARS, the N protein is 422 amino acid residues long and in SARS-CoV-2, the causative agent ... They made available the virus to the wider scientific community shortly thereafter "by depositing it into two virus reagent ... In SARS-CoV, MERS-CoV, and SARS-CoV-2, N has been reported as suppressing interferon responses. The sequences and structures of ... the SARS-CoV N protein has been observed to be SUMOylated and the N proteins of several coronaviruses including SARS-CoV-2 have ...
https://en.wikipedia.org/wiki/Coronavirus_nucleocapsid_protein
GeoVaxGeoVax
Zika Virus Zika virus infection has been linked to an increase in microcephaly in infants and Guillain-Barre syndrome (a ... caused by the SARS-CoV-2 coronavirus. They have completed the design and construction of multiple vaccine candidates and have ... GeoVax technology approach uses recombinant DNA or recombinant viruses to produce virus-like particles (VLPs) in the person ... The MVA expresses the HIV virus-like-particles, but does not express GM-CSF. The regimen builds on the GeoVax DNA/MVA vaccine ...
https://en.wikipedia.org/wiki/GeoVax
Chao Tzee ChengChao Tzee Cheng
They had a son Dr Alexandre Chao, who succumbed to SARS in 2003. Upon his return to Singapore, Chao was appointed the forensic ... Wong Yip Chong claiming that she caught the Japanese encephalitis virus from Hiroshi Watanabe and thus suffered from a viral ...
https://en.wikipedia.org/wiki/Chao_Tzee_Cheng
Vĩnh Phúc provinceVĩnh Phúc province
SARS-CoV 2) virus. Seven of the total of sixteen people contracted the virus in Vietnam are residents of Sơn Lôi Commune - ...
https://en.wikipedia.org/wiki/Vĩnh_Phúc_province
Carolina DariasCarolina Darias
On 12 March 2020, it was reported that Darias had been infected by SARS-CoV-2, the virus that caused coronavirus 2020 pandemic ... She was the second member of the Spanish government to be infected by the virus, after it was reported that Minister of ... Equality Irene Montero had tested positive for the virus earlier the same day. "La consejera canaria Carolina Darias, nueva ...
https://en.wikipedia.org/wiki/Carolina_Darias
Lennart NilssonLennart Nilsson
... he took the first image of the SARS virus. Around 1970 he joined the staff of the Karolinska Institutet. Nilsson was also ... He is generally credited with taking the first images of the human immunodeficiency virus, and in 2003, ...
https://en.wikipedia.org/wiki/Lennart_Nilsson
Josh BallJosh Ball
He was forced to miss the 2021 Hula Bowl, after testing positive for SARS-CoV-2, the virus responsible for the COVID-19 ...
https://en.wikipedia.org/wiki/Josh_Ball
COVID-19 namingCOVID-19 naming
While COVID-19 refers to the disease and SARS-CoV-2 refers to the virus which causes it, referring to the "COVID-19 virus" has ... the International Committee on Taxonomy of Viruses (ICTV) formally announced it had named the causative virus as SARS-CoV-2 ( ... From January to March 2020, US President Donald Trump repeatedly described the virus as the "Chinese virus". In March 2020, the ... "Chinese virus" amid instances of bigotry against Asians in the USA. Trump referred to it as "the China Virus" at least as late ...
https://en.wikipedia.org/wiki/COVID-19_naming
InterferonInterferon
Viruses that inhibit IFN signaling include Japanese Encephalitis Virus (JEV), dengue type 2 virus (DEN-2), and viruses of the ... In the early stages of infection, SARS-CoV-2 induces an even lower interferon type I (IFN-I) response than SARS-CoV, which ... Some viruses escape the anti-viral activities of interferons by gene (and thus protein) mutation. The H5N1 influenza virus, ... SARS-CoV-2 limits the IFN-III response as well. Reduced numbers of plasmacytoid dendritic cells with age is associated with ...
https://en.wikipedia.org/wiki/Interferon
Shelley DeeksShelley Deeks
During the SARS outbreak of 2003, Deeks was working at Health Canada and then moved to the Public Health Agency of Canada in ... has also worked with researchers at SickKids to study the development of asthma following severe respiratory syncytial virus ...
https://en.wikipedia.org/wiki/Shelley_Deeks
COVID-19 pandemic in EuropeCOVID-19 pandemic in Europe
SARS-CoV-2). The virus was confirmed to have reached Andorra on 2 March 2020, when a 20-year-old man returned to the country ... SARS-CoV-2). The virus was confirmed to have spread to Belarus, when the first case of COVID-19 in the country was registered ... SARS-CoV-2). The virus was confirmed to have spread to Bulgaria when the country's first cases, a 27-year-old man from Pleven ... SARS-CoV-2). The virus was confirmed to have reached Bosnia and Herzegovina on 5 March 2020, when a patient in Banja Luka, who ...
https://en.wikipedia.org/wiki/COVID-19_pandemic_in_Europe
ViroporinViroporin
These viruses include hepatitis C virus, HIV-1, influenza A virus, poliovirus, respiratory syncytial virus, and SARS-CoV. ... They are found in a variety of viral genomes but are particularly common in RNA viruses. Many viruses that cause human disease ... Carrasco L (August 1995). "Modification of membrane permeability by animal viruses". Advances in Virus Research. 45: 61-112. ... and the Chlorella virus Kcv protein, which is selective for potassium ions. An alternative mechanism is illustrated by the SARS ...
https://en.wikipedia.org/wiki/Viroporin
Timeline of the COVID-19 pandemic in the Philippines (2021)Timeline of the COVID-19 pandemic in the Philippines (2021)
"PH virus tally breaches half a million less than a year after first case". ABS-CBN News. January 17, 2021. Retrieved January 17 ... Only essential workers were exempted from the said curfew March 18 - A new SARS-CoV-2 variant had emerged in the country named ... January 6 A traveler from the Philippines has been tested positive for the new virus strain of COVID-19 in HK. The patient ... January 3 - The country banned the entry of travelers from the US until January 15, 2021, as the new virus variant was detected ...
https://en.wikipedia.org/wiki/Timeline_of_the_COVID-19_pandemic_in_the_Philippines_(2021)
Workplace hazard controls for COVID-19Workplace hazard controls for COVID-19
... infected with SARS-CoV-2, and those performing aerosol-generating procedures. In the United States, NIOSH-approved N95 ... suggests that the small number of fully vaccinated people who do become infected can be infectious and can spread the virus to ... but may be infected with SARS-CoV-2 due to ongoing community transmission around the business location, or because the ... Disinfectants for Use Against SARS-CoV-2 (COVID-19) (United States Environmental Protection Agency) 24th Collegium Ramazzini ...
https://en.wikipedia.org/wiki/Workplace_hazard_controls_for_COVID-19
CureVac COVID-19 vaccineCureVac COVID-19 vaccine
"mRNA based SARS-CoV-2 vaccine candidate CVnCoV induces high levels of virus neutralizing antibodies and mediates protection in ... Portals: Medicine Viruses COVID-19 (Wikipedia articles in need of updating from December 2021, All Wikipedia articles in need ... Proposed INN: zorecimeran "A Study to Determine the Safety and Efficacy of SARS-CoV-2 mRNA Vaccine CVnCoV in Adults". ... "Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 ...
https://en.wikipedia.org/wiki/CureVac_COVID-19_vaccine
Stephen Holgate (physician)Stephen Holgate (physician)
Linked to clinical trials showing antiviral protection in asthma and COPD and the knowledge that SARS CoV-2 has developed ... Johnston first demonstrated the causal link between exacerbations in the autumn and winter months and respiratory virus ... spin-off company Synairgen to explore the potential therapeutic benefits of inhaled interferon beta in attenuating virus- ...
https://en.wikipedia.org/wiki/Stephen_Holgate_(physician)
History of San MarinoHistory of San Marino
The SARS-CoV-2 virus, a cause of the COVID-19 pandemic, was confirmed to have reached San Marino in February 2020. As of June ...
https://en.wikipedia.org/wiki/History_of_San_Marino
Pardis SabetiPardis Sabeti
In May 2015, she delivered a TED Talk, called "How we'll fight the next deadly virus." "Her team was recently awarded funding ... "Discrete SARS-CoV-2 antibody titers track with functional humoral stability". Nature Communications. 12 (1): 1018. Bibcode: ... "How we'll fight the next deadly virus". www.ted.com. Retrieved 19 May 2016. Bazelon, Emily (3 June 2020). "What Will College Be ... paper in Nature Communications on how a certain level of COVID-19 anti-bodies may provide lasting protection against the virus ...
https://en.wikipedia.org/wiki/Pardis_Sabeti
Yellow fever vaccineYellow fever vaccine
July 2021). "SARS-CoV-2 variants, spike mutations and immune escape". Nature Reviews. Microbiology. 19 (7): 409-424. doi: ... Portals: Medicine Viruses (Articles with short description, Short description matches Wikidata, Use dmy dates from November ... Following the work of Ernest Goodpasture, Theiler used chicken eggs to culture the virus. After field trials in Brazil, over ... Norrby E (November 2007). "Yellow fever and Max Theiler: the only Nobel Prize for a virus vaccine". The Journal of Experimental ...
https://en.wikipedia.org/wiki/Yellow_fever_vaccine
Correlates of immunityCorrelates of immunity
For many viruses, antibodies and especially neutralizing antibodies serve as a correlate of immunity. Pregnant women, for ... SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection". Journal of Biomedical Science. doi: ... Correlates of immunity or correlates of protection to a virus or other infectious pathogen are measurable signs that a person ( ...
https://en.wikipedia.org/wiki/Correlates_of_immunity
COVID-19COVID-19
The SARS-CoV-2 virus can infect a wide range of cells and systems of the body. COVID‑19 is most known for affecting the upper ... Like other enveloped viruses, SARS-CoV-2 survives longest when the temperature is at room temperature or lower, and when the ... Outside the human body, the virus is destroyed by household soap, which bursts its protective bubble. SARS-CoV-2 is closely ... Human angiotensin converting enzyme 2 (hACE2) is the host factor that SARS-CoV-2 virus targets causing COVID‑19. Theoretically ...
https://en.wikipedia.org/wiki/COVID-19
Lancet letter (COVID-19)Lancet letter (COVID-19)
"Les silences de la Chine, un virus repéré dès 2013, la fausse piste du pangolin... Enquête sur les origines du SARS-CoV-2". Le ... Some early rumors focused on the deliberate leak of a virus as a bioweapon or accidental leak of an engineered virus. Some ... "The rise and fall of British virus hunter Peter Daszak". The Times. "Covid origins: Scientists weigh up evidence over virus's ... Bernard Roizman is reported to have said "I'm convinced that what happened is that the virus was brought to a lab, they started ...
https://en.wikipedia.org/wiki/Lancet_letter_(COVID-19)
List of timelinesList of timelines
Progress of the SARS outbreak (2002-2004) Timeline of AIDS (1930s-present) Timeline of antibiotics (1935 CE-present) Timeline ... Timeline of computer viruses and worms (1966-present) Timeline of social media (1979/1980-present) Timeline of Linux kernel ... 2014 Ebola virus disease epidemic timeline (2013-present) Timeline of fundamental physics discoveries (250 BC-present) Timeline ...
https://en.wikipedia.org/wiki/List_of_timelines
COVID-19 pandemic in Easter IslandCOVID-19 pandemic in Easter Island
The case fatality ratio for COVID-19 has been much lower than SARS of 2003, but the transmission has been significantly greater ... Agence France-Presse (5 April 2020). "Easter Island inhabitants turn to tradition to tackle virus troubles". The Jakarta Post. ... Ministry of Health of Chile (15 April 2020). "Informe epidemiológico - Enfermedad por SARS-CoV-2 (COVID-2019)" (PDF) (in ... COVID-19 portal Chile portal Viruses portal Medicine portal COVID-19 pandemic in Chile https://www.covid19level.com/main-list/ ...
https://en.wikipedia.org/wiki/COVID-19_pandemic_in_Easter_Island
Sigma-1 receptorSigma-1 receptor
July 2020). "A SARS-CoV-2 protein interaction map reveals targets for drug repurposing". Nature. 583 (7816): 459-468. Bibcode: ... 2 to inhibit autophagosome formation as a process competing with the coronavirus for cellular endomembranes that the virus ... This along with the observed beneficial effects of sigma-1 receptor agonist and SSRI fluvoxamine in patients with SARS-COV-2 ... σ1R is targeted by the nsp6 protein of SARS-CoV- ... sigma-1 receptor could be a target for the treatment of SARS- ...
https://en.wikipedia.org/wiki/Sigma-1_receptor
History of Australia (1945-present)History of Australia (1945-present)
Late January 2020 was also notable for the first local infections of a new virus, severe acute respiratory syndrome coronavirus ... 2 (SARS-CoV-2). This led into the world-wide COVID-19 pandemic, and the COVID-19 pandemic in Australia that by the end of 2020 ...
https://en.wikipedia.org/wiki/History_of_Australia_(1945–present)
Browsing by Subject SARS VirusBrowsing by Subject "SARS Virus"
Status of environmental surveillance for SARS-CoV-2 virus: scientific brief, 5 August 2020  ... Severe acute respiratory syndrome (‎SARS)‎: report by the Secretariat  Executive Board, 113 (‎World Health Organization, 2004 ... Good Infection Control Practices with Emphasis on Prevention and Control of SARS: report of a regional workshop, Mumbai, India ... Revision of the International Health Regulations: severe acute respiratory syndrome (‎SARS)‎: report by the Secretariat  ...
https://apps.who.int/iris/browse?authority=SARS+Virus&type=mesh
Overview of Testing for SARS-CoV-2, the virus that causes COVID-19 | CDCOverview of Testing for SARS-CoV-2, the virus that causes COVID-19 | CDC
Find an overview for healthcare workers of SARS-CoV-2 testing, considerations for testing, test types, surveillance, and how to ... Overview of Testing for SARS-CoV-2, the virus that causes COVID-19. Overview of Testing for SARS-CoV-2, the virus that causes ... Vaccination and SARS-CoV-2 Testing. Vaccination does not affect the results of someones SARS-CoV-2 diagnostic or screening ... Testing for SARS-CoV-2 Infection. Test Types. Viral tests, including Nucleic Acid Amplification Tests (NAATs, such as PCR tests ...
http://www.cdc.gov/coronavirus/2019-ncov/hcp/testing-overview.html
Browsing by Subject SARS VirusBrowsing by Subject "SARS Virus"
Status of environmental surveillance for SARS-CoV-2 virus: scientific brief, 5 August 2020  ... Severe acute respiratory syndrome (‎SARS)‎: report by the Secretariat  Executive Board, 113 (‎World Health Organization, 2004 ... Good Infection Control Practices with Emphasis on Prevention and Control of SARS: report of a regional workshop, Mumbai, India ... Revision of the International Health Regulations: severe acute respiratory syndrome (‎SARS)‎: report by the Secretariat  ...
https://extranet.who.int/iris/restricted/browse?locale-attribute=en&type=mesh&authority=SARS+Virus
PraneshPadmanabhan2022 - SARS-CoV-2 virus dynamics model (human) | BioModelsPraneshPadmanabhan2022 - SARS-CoV-2 virus dynamics model (human) | BioModels
SARS-CoV-2 virus dynamics ODE model parameterized using non-linear mixed effects fitting to longitudinal human data. ... With comment: Import of PraneshPadmanabhan2022 - SARS-CoV-2 virus dynamics model (human) ... We devel- oped a model of within-host SARS-CoV-2 dynamics, applied it to virtual patient populations and, invoking the NAb ... My paper in Nature Computational Science about COVID virus dynamics models. The paper contains a github link with all model ...
https://www.ebi.ac.uk/biomodels/MODEL2205010001
1st case of new SARS-like virus in US | Live Science1st case of new SARS-like virus in US | Live Science
The new SARS-like virus thats causing an outbreak in China has now arrived in the United States, officials announced today ( ... This family includes the viruses that cause SARS and MERS (Middle East respiratory syndrome), as well as those that cause ... 1st case of new SARS-like virus in US. By Rachael Rettner ... The 9 Deadliest Viruses on Earth * 10 Deadly Diseases That ... However, the man, who is in his 30s, was aware of the reports of this virus, and he reached out to his health care providers ...
https://www.livescience.com/new-coronavirus-first-case-us.html
A Tale of Two Viruses: SARS, Bird Flu, and What They Say About China Then and Now | Asia SocietyA Tale of Two Viruses: SARS, Bird Flu, and What They Say About China Then and Now | Asia Society
Despite similarities between the SARS and bird flu outbreaks, its harder for Chinas government to hide things today than it ... A Tale of Two Viruses: SARS, Bird Flu, and What They Say About China Then and Now April 11th, 2013 ... SARS spooks everyone, and the center where I was supposed to study closes and sends all of its foreign students home. I fill my ... SARS subtly shifted the course of my life (maybe. Who knows?), but it had a tremendous effect on the willingness of the Chinese ...
https://asiasociety.org/blog/asia/tale-two-viruses-sars-bird-flu-and-what-they-say-about-china-then-and-now
Coronavirus: How scientists are tracking 8 strains of SARS-CoV-2 virusCoronavirus: How scientists are tracking 8 strains of SARS-CoV-2 virus
... genomes of eight coronavirus strains circling the globe providing hints about the effectiveness of efforts to halt the virus. ...
https://www.wickedlocal.com/story/news/nation/2020/03/27/scientists-track-coronavirus-strains-mutation/5080571002/
The in-vitro effect of famotidine on SARS-CoV-2 proteases and virus replication | Scientific ReportsThe in-vitro effect of famotidine on SARS-CoV-2 proteases and virus replication | Scientific Reports
While a prospective, multi-center clinical study is ongoing, two parallel in silico studies have proposed one of the two SARS- ... These results rule out famotidine as a direct-acting inhibitor of SARS-CoV-2 replication and warrant further investigation of ... In this report, we systematically analyzed the effect of famotidine on viral proteases and virus replication. Leveraging a ... when tested against SARS-CoV-2 in two different cell lines, including a human cell line originating from lungs, a primary ...
https://www.nature.com/articles/s41598-021-84782-w?error=cookies_not_supported&code=7fc9ad5e-f3ae-4ab0-81d0-d5c8a307f76d
Covid19 Omicron Stock Photo - Download Image Now - SARS-CoV-2 Omicron Variant, Coronavirus, Virus - iStockCovid19 Omicron Stock Photo - Download Image Now - SARS-CoV-2 Omicron Variant, Coronavirus, Virus - iStock
And search more of iStocks library of royalty-free stock images that features SARS-CoV-2 Omicron Variant photos available for ... iStockCovid19 Omicron Stock Photo - Download Image Now - SARS-CoV-2 Omicron Variant, Coronavirus, Virus. Download this Covid19 ... Its a win-win, and its why everything on iStock is only available royalty-free - including all SARS-CoV-2 Omicron Variant ... And search more of iStocks library of royalty-free stock images that features SARS-CoV-2 Omicron Variant photos available for ...
https://www.istockphoto.com/photo/covid-19-omicron-gm1356138738-430387523?utm_source=unsplash&utm_medium=affiliate&utm_campaign=srp_photos_bottom&utm_content=https%3A%2F%2Funsplash.com%2Fs%2Fphotos%2Fcovid-vaccin&utm_term=covid%20vaccin%3A%3A%3A
France reports first case of new SARS-like virus - Page 1 | MediapartFrance reports first case of new SARS-like virus - Page 1 | Mediapart
France reports first case of new SARS-like virus May 8, 2013. By La rédaction de Mediapart ...
https://www.mediapart.fr/en/journal/france/080513/france-reports-first-case-new-sars-virus
SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaquesSARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques
Authorized vaccines against SARS-CoV-2 remain less available in low- and middle-income countries due to insufficient supply, ... SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques Sci Adv. ... Here, a clinical-stage vaccine candidate comprising a SARS-CoV-2 receptor binding domain-hepatitis B surface antigen virus-like ... Authorized vaccines against SARS-CoV-2 remain less available in low- and middle-income countries due to insufficient supply, ...
https://pubmed.ncbi.nlm.nih.gov/35294244/
European Tribune - Comments - Milton Leitenberg SARS-CoV-2 virus WeaponizedEuropean Tribune - Comments - Milton Leitenberg SARS-CoV-2 virus Weaponized
Milton Leitenberg SARS-CoV-2 virus Weaponized , 94 comments (94 topical, 0 editorial, 0 hidden) ... Milton Leitenberg SARS-CoV-2 virus Weaponized , 94 comments (94 topical, editorial, 0 hidden) ...
https://www.eurotrib.com/comments/2021/6/9/17442/56863/77
Omicron Virus News: Scientists identify antibodies that might neutralise Omicron, other SARS-CoV-2 variants - The Economic...Omicron Virus News: Scientists identify antibodies that might neutralise Omicron, other SARS-CoV-2 variants - The Economic...
These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses mutate. The studys ... an international team of scientists identified antibodies that neutralise Omicron and other SARS-CoV-2 variants. ... These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses mutate. The studys ... Scientists identify antibodies that might neutralise Omicron, other SARS-CoV-2 variants. ANI , 29 Dec 2021, 07:13 AM IST. ...
https://economictimes.indiatimes.com/industry/healthcare/biotech/healthcare/scientists-identify-antibodies-that-might-neutralise-omicron-other-sars-cov-2-variants/videoshow/88556122.cms
Risk and protective factors for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare workers: A...Risk and protective factors for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare workers: A...
SARS-CoV-2) infection among healthcare workers: A test-negative case-control study in Québec, Canada ... Risk and protective factors for severe acute respiratory coronavirus virus 2 ( ... Chou, R, Dana, T, Jungbauer, R. Update alert 7: masks for prevention of respiratory virus infections, including SARS-CoV-2, in ... In Québec, Canada, we evaluated the risk of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection associated with ...
https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/abs/risk-and-protective-factors-for-severe-acute-respiratory-coronavirus-virus-2-sarscov2-infection-among-healthcare-workers-a-testnegative-casecontrol-study-in-quebec-canada/743C9702FD1C210B6CF391C5D6904F51
China says Wuhan pneumonia not Sars, but virus remains unidentified, more people hospitalised | South China Morning PostChina says Wuhan pneumonia not Sars, but virus remains unidentified, more people hospitalised | South China Morning Post
Although the total number of infections has increased in the mainland city, there are fewer people in serious condition, according to the Wuhan Municipal Commission.
https://www.scmp.com/news/hong-kong/health-environment/article/3044723/six-more-hong-kong-patients-hospitalised-over
The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2 | medRxivThe landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2 | medRxiv
The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2. View ORCID ProfileLinda Kachuri, ... The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2 ... The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2 ... The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2 ...
https://www.medrxiv.org/content/10.1101/2020.05.01.20088054v2.article-metrics
Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates ...Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates ...
Particularly, mutations in SARS-CoV-2 spike-glycoprotein are of great interest as it mediates infection in human and recently ... We analyzed 1,036,030 SARS-CoV-2 genome assemblies and 30,806 NGS datasets from GISAID and European Nucleotide Archive (ENA) ... These findings demonstrate the continuous importance of monitoring SARS-CoV-2 sequences for an early detection of variants that ... which might indicate co-infection with various SARS-CoV-2 strains and/or intra-host evolution. Lastly, some variants might have ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0249254
COVID-19 Services: SARS-CoV-2 Virus Detection ServicesCOVID-19 Services: SARS-CoV-2 Virus Detection Services
Highly sensitive - can detect just a few virus particles. *Safe to perform - the sampling process inactivates (kills) the virus ... Our analysis reduces the potential for false negatives by detecting unique SARS-CoV-2 genes on the viral RNA. Positive and ... the gold standard method for detecting SARS-CoV-2. ... SARS-CoV-2 Virus Detection Services. *COVID-19 Services: SARS- ... COVID-19 Services: SARS-CoV-2 Sampling and Verification Testing. *COVID-19 Services: ...
https://www.geosyntec.com/covid-19/virus-detection-services
CHP investigates locally acquired SARS-CoV-2 virus cases with 1 046 cases tested positive by nucleic acid tests and 2 937 cases...
Hong Kong has so far recorded a total of 10 202 death cases that tested positive for the SARS-CoV-2 virus.. Furthermore, among ... In addition, as of 0.00am, October 7, a total of 9 989 death cases that had tested positive for the SARS-CoV-2 virus during the ... CHP investigates locally acquired SARS-CoV-2 virus cases with 1 046 cases tested positive by nucleic acid tests and 2 937 cases ... CHP investigates locally acquired SARS-CoV-2 virus cases with 1 046 cases tested positive by nucleic acid tests and 2 937 cases ...
https://www.info.gov.hk/gia/general/202210/07/P2022100700369.htm
COVID 19 Vaccine approved and launched in Côte dIvoire. Corona Virus SARS CoV 2, 2021 nCoV vaccine delivery. Côte dIvoire...COVID 19 Vaccine approved and launched in Côte d'Ivoire. Corona Virus SARS CoV 2, 2021 nCoV vaccine delivery. Côte d'Ivoire...
Corona Virus SARS CoV 2, 2021 nCoV vaccine delivery. Côte dIvoire flag on background and vaccine bottle. 3D illustration Stock ... Corona Virus SARS CoV 2, 2021 nCoV vaccine delivery. Côte dIvoire flag on background and vaccine bottle. 3D illustration ...
https://stock.adobe.com/images/covid-19-vaccine-approved-and-launched-in-cote-d-ivoire-corona-virus-sars-cov-2-2021-ncov-vaccine-delivery-cote-d-ivoire-flag-on-background-and-vaccine-bottle-3d-illustration/418798228
Americas Top Young Scientist of 2020: 14-Year-Old Researches Spike Protein of SARS-CoV-2 Virus to Develop Novel Antiviral Drug...America's Top Young Scientist of 2020: 14-Year-Old Researches Spike Protein of SARS-CoV-2 Virus to Develop Novel Antiviral Drug...
The SARS-CoV-2 virus is the cause of hundreds of thousands of deaths worldwide and was declared a worldwide pandemic and public ... The one molecule with the best pharmacological and biological activity towards the spike protein of the SARS-CoV-2 virus was ... Americas Top Young Scientist of 2020: 14-Year-Old Researches Spike Protein of SARS-CoV-2 Virus to Develop Novel Antiviral Drug ... silico methodology for drug discovery to find a molecule that can selectively bind to the spike protein of the SARS-CoV-2 virus ...
https://www.discoveryeducation.com/details/americas-top-young-scientist-of-2020-14-year-old-researches-spike-protein-of-sars-cov-2-virus-to-develop-novel-antiviral-drug-to-combat-spread-of-covid-19/
Covid, Shocking Claim by Italian Infectious Diseases Institute: Risks of Confusion between seasonal Flu and SARS-2 Virus - VT...Covid, Shocking Claim by Italian Infectious Diseases Institute: "Risks of Confusion between seasonal Flu and SARS-2 Virus" - VT...
Covid, Shocking Claim by Italian Infectious Diseases Institute: "Risks of Confusion between seasonal Flu and SARS-2 Virus". By ... The tests being used now do distinguish between the COVID-19 virus and the common influenza virus. The test are looking for ... SARS-CoV-2) not any old virus, such as the yearly influenza. There are two types of tests for COVID-19 and those are viral ... Stopping the ability of COVID-19 viral droplets will also stop the spread of any other virus or bacteria that can travel in the ...
https://www.veteranstoday.com/2020/11/15/covid-shocking-claim-by-italian-infectious-diseases-institute-risks-of-confusion-between-seasonal-flu-and-sars-2-virus/
COVID-19 expert explains what soap does to SARS-CoV-2 virus - Mayo Clinic News NetworkCOVID-19 expert explains what soap does to SARS-CoV-2 virus - Mayo Clinic News Network
COVID-19 expert explains what soap does to SARS-CoV-2 virus. April 2, 2020. ... explains what soap does to SARS-CoV-2, and other viruses and bacteria. ... A. Your hand has oils on it, and viruses stick to that oil. They have an electrostatic charge to them. But when youre washing ... soap has things that decrease surface tension in them so you are physically rubbing by friction and washing away that virus. It ...
https://newsnetwork.mayoclinic.org/discussion/covid-19-expert-explains-what-soap-does-to-sars-cov-2-virus/
Functional biochip based on ultra-low fouling polymer for rapid detection of SARS-COV-2 virus in crude biological fluids | FZUFunctional biochip based on ultra-low fouling polymer for rapid detection of SARS-COV-2 virus in crude biological fluids | FZU
Functional biochip based on ultra-low fouling polymer for rapid detection of SARS-COV-2 virus in crude biological fluids. ... Functional biochip based on ultra-low fouling polymer for rapid detection of SARS-COV-2 virus in crude biological fluids ...
https://www.fzu.cz/sluzby/patenty-a-licence/databaze-patentu/functional-biochip-based-ultra-low-fouling-polymer-rapid
Inhaled Nitric Oxide Kills SARS-COV-2 virus, finds joint study by Amrita Hospital and Amrita Vishwa Vidyapeetham - Amrita...Inhaled Nitric Oxide Kills SARS-COV-2 virus, finds joint study by Amrita Hospital and Amrita Vishwa Vidyapeetham - Amrita...
The study conducted by the Amrita scientists has found that inhaled Nitric Oxide (iNO) is virucidal and kills SARS-COV-2 virus ... HomeNewsInhaled Nitric Oxide Kills SARS-COV-2 virus, finds joint study by Amrita Hospital and Amrita Vishwa Vidyapeetham ... Inhaled Nitric Oxide Kills SARS-COV-2 virus, finds joint study by Amrita Hospital and Amrita Vishwa Vidyapeetham. February 4, ... coronavirusAmrita HospitalSARS-COV-2 virus2022AmritaAmrita School of Biotechnology ...
https://www.amrita.edu/news/inhaled-nitric-oxide-kills-sars-cov-2-virus-finds-joint-study-by-amrita-hospital-and-amrita-vishwa-vidyapeetham/
3D Printed ACTIVAT3D Copper Proven to Kill SARS-Cov-2 Virus on Contact Surfaces | EPICOS3D Printed ACTIVAT3D Copper Proven to Kill SARS-Cov-2 Virus on Contact Surfaces | EPICOS
3D Printed ACTIVAT3D Copper Proven to Kill SARS-Cov-2 Virus on Contact Surfaces. DARWIN, Australia, April 15, 2020 /PRNewswire ... Laboratory tests have shown that touch surfaces modified by this process contact kills 96% of SARS-CoV-2, the virus that ... The results showed that 96% of the virus is killed in two hours and 99.2% of the virus killed in 5 hours, while stainless steel ... Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1. medRxiv. ...
https://www.epicos.com/article/567022/3d-printed-activat3d-copper-proven-kill-sars-cov-2-virus-contact-surfaces
BAuA - Research - Analysis of job-related health effects of the SARS--Severe acute respiratory syndrome-CoV--Corona virus-2...BAuA - Research - Analysis of job-related health effects of the SARS--Severe acute respiratory syndrome-CoV--Corona virus-2...
Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany. Suchergebnis_Format ... Analysis of job-related health effects of the SARS-CoV-2 pandemic based on the National Cohort in Germany (NAKO Health Study). ... Berufsbezogenes Risiko einer SARS-CoV-2-Infektion in der ersten Welle der COVID-19-Pandemie. Suchergebnis_Formatbaua: Report ... Does the risk of workers to be infected with SARS-CoV-2 at work depend on their occupation? Policymakers, organisations, and ...
https://www.baua.de/EN/Tasks/Research/Research-projects/f2515.html?nn=e8ba5fd8-e813-4e5d-ad95-69c50dcc16f0
Is a New SARS-like Virus Spreading in the Middle East? (Forbes, November 24 2012, extract) - FluTrackers News and...Is a New SARS-like Virus Spreading in the Middle East? (Forbes, November 24 2012, extract) - FluTrackers News and...
Is a New SARS-like Virus Spreading in the Middle East?. As with most emerging epidemics, we usually ignore them until people ... Is a New SARS-like Virus Spreading in the Middle East? (Forbes, November 24 2012, extract). [Source: Forbes, full page: (LINK ... If the same logic applies here, it?s time to begin paying attention to the new SARS-like virus found in Saudi Arabia and Qatar ... Re: Is a New SARS-like Virus Spreading in the Middle East? (Forbes, November 24 2012, extract). Seems some writers cant resist ...
https://flutrackers.com/forum/forum/novel-coronavirus-ncov-mers-2012-2014/136965-is-a-new-sars-like-virus-spreading-in-the-middle-east-forbes-november-24-2012-extract?view=stream
Causes COVID-19InfectionPandemic2020Severe Acute ReVariantsVaccinesMERS2021CoronavirusesPathogenSymptomsOutbreakProteinCorona VirusAntibodiesInfluenzaParticlesAntibodyVaccineFungi2019GeneticSpikeNucleic-acidWuhanOutbreaksInfectsExposureEpidemicDetectionOmicronStrainsAntigenGenomicBacteria and VirusesGenomeDropletsSpreadsSurveillancePneumoniaMutateAerosolsLaboratoryMutationsScientistsSequencingTransmissionSurfacesPreventionAirborneSyndromeImmuneReplicationSusceptibilityReinfectionRespiratory virusesConcentrationInfectPhylogeneticRabiesProteaseVariant
Causes COVID-1911
  • Laboratory tests have shown that touch surfaces modified by this process 'contact kills' 96% of SARS-CoV-2, the virus that causes COVID-19, in just two hours. (epicos.com)
  • During this COCA Call, clinicians will learn critical information about molecular approaches for clinical and public health applications to detect the influenza virus and SARS-CoV-2, the virus that causes COVID-19. (cdc.gov)
  • SARS-CoV-2 is the virus that causes Covid-19 disease. (livemint.com)
  • The Coronavirus Disease 2019 (COVID-19) pandemic has raised many questions about the transmission of the virus that causes COVID-19, SARS-CoV-2, including the possibility of aerosol transmission. (cdc.gov)
  • This protein triggers an immune response to the SARS-CoV-2 virus, which causes COVID-19. (vcuhealth.org)
  • Our lab serology blood tests running on ARCHITECT and Alinity i systems are used for the detection of antibodies, IgG and IgM, and to identify if a person was previously infected with the virus that causes COVID-19. (abbott.com)
  • In each sample, they will look for antibodies (a crucial part of the immune response) against the virus that causes COVID-19, called SARS-CoV-2, as well as related coronaviruses that cause the common cold, and the SARS-Cov-1 virus that emerged in 2003. (rochester.edu)
  • Genetic variations of viruses, such as the one that causes COVID-19, are common and expected. (gnb.ca)
  • SARS-CoV-2, the virus that causes COVID-19, will naturally develop mutations, which are changes to the genetic material in the virus over time. (gnb.ca)
  • All three of the authorized vaccines in the U.S. work by giving the body instructions for making the spike protein from the SARS-CoV-2 virus that causes COVID-19. (springfieldnewssun.com)
  • LiU scientists are working intensely to develop two different analysis methods for the immune response that follows infection by the SARS-CoV-2 virus, which causes COVID-19. (liu.se)
Infection35
  • People who have symptoms of COVID-19 or who have had known exposure to someone with COVID-19 should be tested for SARS-CoV-2 infection. (cdc.gov)
  • This overview describes current information on the types of tests used to detect SARS-CoV-2 infection and their intended uses. (cdc.gov)
  • Viral tests , including Nucleic Acid Amplification Tests (NAATs, such as PCR tests), antigen tests and other tests (such as breath tests) are used as diagnostic tests to detect current infection with SARS-CoV-2, determine the need for prevention measures like isolation, and to inform an individual's medical care. (cdc.gov)
  • Negative results do not rule out SARS-CoV-2 infection and should not be used as the sole basis for treatment or patient management decisions, including infection control decisions. (cdc.gov)
  • Prolonged infection in immunocompromised pa- human immunodeficiency virus infection on the burden of tients may lead to emergence of new virus variants. (cdc.gov)
  • We report a case of a prolonged clinical infection with persistent virus shedding in a patient with func- tional B-cell deficiency, hypogammaglobulinemia, 1These authors contributed equally to this article. (cdc.gov)
  • Viral tests , including Nucleic Acid Amplification Tests (NAATs, such as Reverse Transcription - Polymerase Chain Reaction), antigen tests and other tests (such as breath tests) are used as diagnostic tests to detect current infection with SARS-CoV-2 and to inform an individual's medical care. (cdc.gov)
  • In Québec, Canada, we evaluated the risk of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection associated with (1) the demographic and employment characteristics among healthcare workers (HCWs) and (2) the workplace and household exposures and the infection prevention and control (IPC) measures among patient-facing HCWs. (cambridge.org)
  • This project therefore aimed at finding out whether workers of different occupational groups have an increased risk of infection with SARS - CoV -2 due to their specific working conditions, as for example because they have frequent contact with colleagues or customers. (baua.de)
  • Humans and viruses have co-evolved for millennia resulting in genetic polymorphisms that affect response to viral infection. (medrxiv.org)
  • The signs and symptoms of the SARS patients met the World Health Organization's definition for surveillance, and SARS-CoV infection had been confirmed virologically. (cdc.gov)
  • Infection with the SARS virus causes acute respiratory distress (severe breathing difficulty), and sometimes death. (medlineplus.gov)
  • ComCor study on places of infection with SARS-CoV-2: where are French people catching the virus? (eurekalert.org)
  • The Institut Pasteur, in partnership with the French National Health Insurance Fund (CNAM), Santé publique France and the Ipsos Social Research Institute, recently presented the results of the ComCor epidemiological study on circumstances and places of infection with the SARS-CoV-2 virus. (eurekalert.org)
  • The aim of the study was to identify the socio-demographic factors, places visited and behaviors associated with a higher risk of infection with SARS-CoV-2. (eurekalert.org)
  • Research into the mechanisms of long-term Covid disease shows that it can be caused by damage from the initial infection, but also by persistence of the virus and inflammation in certain areas of the human body. (yourdecommissioningnews.com)
  • Due to high secondary infection rates in household members, there is a need to understand airborne transmission of SARS-CoV-2 within residences. (cdc.gov)
  • The post-acute sequelae of SARS-CoV-2 infection (PASC) refers to a broad spectrum of symptoms and signs that are persistent, exacerbated or newly incident in the period after acute SARS-CoV-2 infection. (nature.com)
  • We created a development cohort from INSIGHT and a validation cohort from OneFlorida+ including 20,881 and 13,724 patients, respectively, who were SARS-CoV-2 infected, and we investigated their newly incident diagnoses 30-180 days after a documented SARS-CoV-2 infection. (nature.com)
  • These subphenotypes were associated with distinct patient demographics, underlying conditions before SARS-CoV-2 infection and acute infection phase severity. (nature.com)
  • The ongoing global pandemic of Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has impacted hundreds of millions of people's lives. (nature.com)
  • It has been suggested that angiotensin converting enzyme inhibitors (ACE-1 inhibitors), such as enalapril and ramipril, and angiotensin receptor antagonists (colloquially called angiotensin receptor blockers or ARBs), such as candesartan and valsartan, may be of value in preventing and treating the effects of the coronavirus SARS-CoV-2 (also known as 2019-nCoV), the cause of the infection called COVID-19. (cebm.net)
  • In the study, a single dose of ABP 300 blocked infection of SARS-CoV-2 in rhesus monkeys and cleared SARS-CoV-2 in three days when given as a therapeutic. (scienceboard.net)
  • Antigen tests detect proteins of the SARS-CoV-2 virus that form during the infection cycle and indicate that a person has an active infection. (abbott.com)
  • Rising cases of infectious diseases caused due to the pathogenic organisms such as bacteria, fungi, viruses and other parasitic organism are improving the adoption of infection preventing products. (medgadget.com)
  • Pascal Soriot, Chief Executive Officer, said: "The long-acting antibody combination has the potential to offer almost immediate protection to those who are not able to be vaccinated, to both prevent infection or treat the disease in patients already infected with the virus. (cision.com)
  • AZD7442 is a combination of two LAABs derived from convalescent patients after SARS-CoV-2 infection. (cision.com)
  • 1-4 The reduced Fc receptor binding aims to minimise the risk of antibody-dependent enhancement of disease - a phenomenon in which virus-specific antibodies promote, rather than inhibit, infection and/or disease. (cision.com)
  • The STORM CHASER 7 Phase III trial is assessing the safety and efficacy of AZD7442 compared to placebo for the prevention of COVID-19 in about 1,125 participants after exposure to a specific identified individual with laboratory-confirmed SARS-COV-2 infection (post-exposure prophylaxis). (cision.com)
  • PROVENT 6 is a Phase III trial assessing the safety and efficacy of AZD7442 compared to placebo for the prevention of COVID-19 in approximately 5,000 adults who are at increased risk for SARS-CoV-2 infection due to living or work situations, or who are at increased risk of responding inadequately to vaccines, such as those with compromised immune systems. (cision.com)
  • The spike protein, which resembles a stem with three buds on the end, is what enables the actual virus to invade cells and cause infection. (springfieldnewssun.com)
  • Although SARS-CoV-2 infection provides protection through acquired immunity , it also carries the risk for severe illness. (medscape.com)
  • An interdisciplinary research team with members from both the Faculty of Medicine and Health Sciences and the Faculty of Science and Engineering started work to develop two different tests, based on the immune response that is triggered by infection with SARS-CoV-2. (liu.se)
  • If, in contrast, the blood contains neutralising antibodies, the researchers can get an idea of how strong the protection is by determining the fraction of cells that survive infection after treatment with different amounts of the virus. (liu.se)
  • One of the most important questions, of course, is whether the neutralising antibodies provide real protection against repeat infection with SARS-CoV-2, and how long the protection lasts. (liu.se)
Pandemic14
  • The lack of coronavirus-specific antiviral drugs has instigated multiple drug repurposing studies to redirect previously approved medicines for the treatment of SARS-CoV-2, the coronavirus behind the ongoing COVID-19 pandemic. (nature.com)
  • The SARS-CoV-2 virus is the cause of hundreds of thousands of deaths worldwide and was declared a worldwide pandemic and public health emergency earlier this year. (discoveryeducation.com)
  • Zhong Nanshan's 2003 SARS "pandemic" was a dud. (nomorefakenews.com)
  • This is particularly evident with this Covid-19 pandemic, where several discoveries on other viruses allow us to better characterize Sars-Cov-2. (yourdecommissioningnews.com)
  • As Lunar Year (Chinese New Year) starts this Saturday, millions of Chinese travellers expected to travel both locally and internationally, burning fears of further spread of the virus and horrible memories of deadly Sars pandemic in 2002 & 2003 that killed around 800 people globally. (planetnews.com)
  • The Sars pandemic - also caused due to a coronavirus - cost the economy tens of billions of dollars globally. (planetnews.com)
  • SARS, and novel influenza viruses, like pandemic H1N1. (cdc.gov)
  • Since the coronavirus disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared a pandemic by the World Health Organization on 11 March 2020, vaccine development and administration became a global priority. (ecancer.org)
  • Throughout the COVID-19 pandemic, public health officials have used the CDC/ATSDR SVI to identify and support areas across the country that are at increased risk of becoming exposed to this highly contagious virus. (cdc.gov)
  • Prior to the emergence of new mutants of the coronavirus, such as the British variant B.1.1.7, the SARS-CoV-2 variant named D614G had already mutated from the original SARS-CoV-2 pathogen that triggered the pandemic. (unibe.ch)
  • While there has been some debate about "immunity debt" or "immunity gap" - namely, that we're seeing a greater number of respiratory infections after hunkering down for the first two years of the pandemic, and limiting our exposure to these viruses - experts say the pandemic played a role. (yahoo.com)
  • Fauci discussed the origins of the SARS-CoV-2 strain of coronavirus, and its subsequent transmission throughout the world, calling it the "worst respiratory pandemic we've had in 102 years since the now-infamous 1918 flu. (health.mil)
  • Peter and I began to investigate and research COVID-19, the SARS-CoV-2 virus and the pandemic in February as the disease began its spread through China into Northern Italy, Spain and then consumed the world. (breggin.com)
  • The pandemic caused by Corona Virus 19 of cases(5). (bvsalud.org)
20208
  • However, the suspension of activities will cease to be applicable as of May 18, 2020 in municipalities that present low or no known cases or transmission of the SARS-CoV2 virus, subject to criteria to be defined by the Secretariat of Health. (pressebox.com)
  • 11. 2020 v zvezi z izvajanjem in financiranjem mikrobioloških preiskav na virus SARS-CoV-2 na podlagi 41. (zdravniskazbornica.si)
  • In January 2020, the agency activated the guidance for the first time in response to the SARS-CoV-2 public health emergency. (reckitt.com)
  • We describe results obtained during May 10, 2020-June 12, 2021, and compare persons with positive and negative SARS-CoV-2 PCR results by using Poisson regression. (medscape.com)
  • During March 2020, two pilot COVID-19 sentinel surveillance projects in California [ 1 , 2 ] detected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among outpatients who had mild influenza-like illness (ILI) and no known travel or COVID-19 contact, suggesting widespread community transmission. (medscape.com)
  • In this episode, published on 4 September 2020, Dr Maria Van Kerkhove explains how the SARS-CoV-2 virus infects the body and how our body's immune system reacts. (bvsalud.org)
  • In early 2020, the SARS-CoV-2 virus spread across the globe, and COVID-19 has now taken the lives of millions of people worldwide. (cdc.gov)
  • 2020). It is not clear if low concentrations of viable virus could accumulate in certain locations in an HVAC system. (cdc.gov)
Severe Acute Re11
  • The disease my co-worker has warned me about is SARS (Severe Acute Respiratory Syndrome), which would eventually kill hundreds of people around the world and sicken thousands. (asiasociety.org)
  • A large part of the current therapeutic discovery effort against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV)-2 is focused on drug repurposing 1 . (nature.com)
  • Lastly, based on 1028 subjects tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we identify 7 class II HLA susceptibility alleles (5 associated with other viruses). (medrxiv.org)
  • We report here the engineering and recovery of nsp14-ExoN mutant viruses of severe acute respiratory syndrome coronavirus (SARS-CoV) that have stable growth defects and demonstrate a 21-fold increase in mutation frequency during replication in culture. (jcvi.org)
  • State and local health departments established the California Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Respiratory Virus Sentinel Surveillance System to conduct enhanced surveillance for SARS-CoV-2 and other respiratory pathogens at sentinel outpatient testing sites in 10 counties throughout California, USA. (medscape.com)
  • Using immunofluorescence and neutralization assays, we detected antibodies to human severe acute respiratory syndrome-associated coronavirus (SARS-CoV) and/or animal SARS-CoV-like virus in 17 (1.8%) of 938 adults recruited in 2001. (cdc.gov)
  • A novel coronavirus has been identified as the cause of the 2003 global outbreak of severe acute respiratory syndrome (SARS) ( 1 - 5 ). (cdc.gov)
  • Correlation between antibodies against human severe acute respiratory syndrome cornonavirus (SARS-CoV) (anti-Hu SARS-CoV) and animal (anti-An) SARS-CoV-like virus in seropositive healthy adults recruited in 2001 (dotted line) and in patients with. (cdc.gov)
  • Wastewater-based epidemiology has been described as a valuable tool for monitoring the spread of severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ) in a community . (bvsalud.org)
  • Severe acute respiratory syndrome (SARS) is a serious form of pneumonia . (medlineplus.gov)
  • The exceptional speed of COVID-19 vaccine development is due to years of prior research on other viruses, including coronaviruses such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). (vcuhealth.org)
Variants16
  • These data support the potential benefit of this design for a low-cost modular vaccine platform for SARS-CoV-2 and other variants of concern or betacoronaviruses. (nih.gov)
  • During a recent study, an international team of scientists identified antibodies that neutralise Omicron and other SARS-CoV-2 variants. (indiatimes.com)
  • The SARS-CoV-2 Omicron variant (B.1.1.529) causes less severe disease than previous SARS-CoV-2 variants, although immune protection provided by vaccinations and previous infections is reduced against Omicron compared to previous variants. (kent.ac.uk)
  • In agreement, evidence is emerging that Omicron is inherently less pathogenic than previous SARS-CoV-2 variants. (kent.ac.uk)
  • Omicron variant viruses cause less severe disease in animal studies and appear to display a lower capacity than other variants to replicate in the lower respiratory tract. (kent.ac.uk)
  • Additionally, initial clinical data indicated that the Omicron variant causes less severe disease than previous SARS-CoV-2 variants in unvaccinated individuals. (kent.ac.uk)
  • Notably, the Omicron and Delta virus isolates that we investigated (see Supplementary Information) display sequence variants in the viral interferon antagonists nsp3, nsp12, nsp13, nsp14, the membrane (M) protein, the nucleocapsid protein, and ORF3a5 (Supplementary Table S1), which may be of relevance. (kent.ac.uk)
  • SARS-CoV-2 variations have been grouped by medical trackers into four broad categories: variants being monitored, variants of interest, variants of concern, and variants of high consequence. (tallandtruetales.blog)
  • In the countries where there is a high spread of the variants and in countries where we now have information about the use of this vaccine to control SARS-CoV-2 caused by these variants, we recommend that you use it. (livemint.com)
  • The findings are extremely important for assessing the risk of new mutants running rampant, as they show how a fitness advantage of virus variants can lead to higher transmission. (unibe.ch)
  • To compare the two variants, a mixture of equal parts of the original version of the SARS-CoV-2 virus and the D614G variant was applied into the nose of each animal under light anesthesia. (unibe.ch)
  • Our testing strategy allows us to rapidly examine why other, newly emerging virus variants have become established,' says Volker Thiel. (unibe.ch)
  • Pfizer did say that it has conducted research "where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. (whatreallyhappened.com)
  • The combination of LAABs is also designed to reduce the risk of resistance developed by the SARS-CoV-2 virus and its variants. (cision.com)
  • Genomic surveillance of SARS-CoV-2 is helping us spot new variants and figure out how to respond. (technologyreview.com)
  • The new variants of concern include mutations that seem to make the virus more infectious, allowing it to spread more easily. (gnb.ca)
Vaccines9
  • Authorized vaccines against SARS-CoV-2 remain less available in low- and middle-income countries due to insufficient supply, high costs, and storage requirements. (nih.gov)
  • The spokesman for the CHP said that COVID-19 vaccines are highly effective in preventing severe cases and deaths from the SARS-CoV-2 virus. (gov.hk)
  • More specifically, these patents discuss ways of weakening viruses or extracting material from them for the purposes of developing vaccines. (nomorefakenews.com)
  • Learn about our tools that are helping researchers develop diagnostics and vaccines for the SARS-CoV-2 virus. (neb.com)
  • mRNA vaccines don't contain any live virus, nor do they contain a weakened or inactivated form of the virus. (vcuhealth.org)
  • This type of knowledge could help support research about how the virus spreads within communities and immune responses to vaccines. (abbott.com)
  • Of interest is the role of adenoviruses as viral vectors in vaccination and in gene therapy.For example, in viral vector vaccines against SARS-CoV2, the vector virus is used to deliver RNA encoding SARS-CoV2 spike protein into target cells. (medscape.com)
  • This phenomenon can make it more difficult to develop vaccines against these viruses, so it is critical to know whether it happens in COVID-19. (rochester.edu)
  • According to the World Health Organization (WHO), a variant of concern (VOC) "translates to a rise in transmissibility, an increase in fatality and a significant decrease in effectiveness of vaccines, therapy and other health measures," while a variant of interest (VOI) is a "variant with a genetic capability that affects characteristics of the virus such as disease severity, immune escape, transmissibility and diagnostic escape. (sunstar.com.ph)
MERS4
  • This family includes the viruses that cause SARS and MERS (Middle East respiratory syndrome), as well as those that cause milder illnesses, like the common cold. (livescience.com)
  • Recent outbreaks of SARS, MERS, and EVD have reinvigorated interest in quantifying risks associated with this mode of global travel. (cdc.gov)
  • That hijacking, called antibody-dependent enhancement, happens in viral infections that are similar to COVID-19, like SARS and MERS, as well as Zika and Dengue. (rochester.edu)
  • From SARS to MERS, thrusting coronaviruses into the spotlight. (bvsalud.org)
20212
  • In addition, as of 0.00am, October 7, a total of 9 989 death cases that had tested positive for the SARS-CoV-2 virus during the fifth wave (since December 31, 2021) were recorded, with 9 904 and 82 deaths reported from the Hospital Authority and public mortuaries respectively as well as three deaths reported from the Chinese University of Hong Kong Medical Centre. (gov.hk)
  • Corona Virus SARS CoV 2, 2021 nCoV vaccine delivery. (adobe.com)
Coronaviruses3
  • Coronaviruses are a large family of viruses that cause respiratory illnesses, according to the CDC. (livescience.com)
  • Coronaviruses are single-stranded RNA viruses, about 120 nanometers in diameter. (cebm.net)
  • Coronaviruses are a large family of viruses. (gnb.ca)
Pathogen2
  • Before pesticide products can legally make claims that they can kill a particular pathogen such as SARS-CoV-2, the claim must be authorized by EPA based on a review of data. (reckitt.com)
  • We also detected 23 co-infections with SARS-CoV-2 and another pathogen. (medscape.com)
Symptoms8
  • However, the man, who is in his 30s, was aware of the reports of this virus, and he reached out to his health care providers when he started experiencing symptoms, Dr. Scott Lindquist, an epidemiologist for Washington state's Department of Health, said in a news conference today. (livescience.com)
  • The symptoms are indistinguishable from SARS. (nomorefakenews.com)
  • Serologic surveillance demonstrated that, in the same market, approximately 40% of wild animal traders and 20% of animal slaughterers had antibodies to SARS-CoV or SARS-CoV-like animal virus, but none of them had had SARS-like symptoms in the past 6 months. (cdc.gov)
  • Symptoms usually occur about 2 to 10 days after coming in contact with the virus. (medlineplus.gov)
  • Overall it is the best combination, to cover all the SARS symptoms we know so far! (foreverhealthywater.com)
  • To explain the persistence of symptoms associated with Covid, one hypothesis being studied is that the virus, even if it is absent, sends signals to the central nervous system. (yourdecommissioningnews.com)
  • Symptoms may appear 2-14 days after exposure to the virus. (cdc.gov)
  • Although the common respiratory virus normally causes coldlike symptoms that typically resolve in a week or so, RSV can be severe in infants and elderly people , according to the CDC, as well as in those who are immunocompromised. (yahoo.com)
Outbreak11
  • The new SARS-like virus that's causing an outbreak in China has now arrived in the United States, officials announced today (Jan. 21). (livescience.com)
  • Tomorrow (Jan. 22), the World Health Organization (WHO) will hold an emergency meeting to determine whether the new virus "constitutes a public health emergency" and what recommendations should be made to manage the outbreak, Tedros Adhanom Ghebreyesus, the director-general of the WHO, said on Twitter . (livescience.com)
  • The guidance allows product manufacturers to provide EPA with data, even in advance of an outbreak, that shows their products are effective against harder-to-kill viruses than SARS-CoV-2. (reckitt.com)
  • This finding suggests that a small proportion of healthy persons in Hong Kong had been exposed to SARS-related viruses at least 2 years before the recent SARS outbreak. (cdc.gov)
  • These investigations raised questions about whether the presence of the animal SARS-CoV-like virus in the market was an isolated event or if this virus had been prevalent in the human population in southern China before the SARS outbreak. (cdc.gov)
  • This article is about the outbreak of SARS that occurred in 2003. (medlineplus.gov)
  • For information about the COVID-19 outbreak caused by SARS-CoV-2, please see the Centers for Disease Control and Prevention (CDC) website. (medlineplus.gov)
  • In the 2003 outbreak, the death rate from SARS was 9% to 12% of those diagnosed. (medlineplus.gov)
  • If a SARS outbreak occurs, reducing your contact with people who have SARS lowers your risk for the disease. (medlineplus.gov)
  • Avoid travel to places where there is an uncontrolled SARS outbreak. (medlineplus.gov)
  • Fact: Between 2002-2004 SARS CoV outbreak happened in China. (tasniaponkti.com)
Protein13
  • These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses mutate. (indiatimes.com)
  • Anika used in-silico methodology for drug discovery to find a molecule that can selectively bind to the spike protein of the SARS-CoV-2 virus to find a cure for COVID-19. (discoveryeducation.com)
  • In her study, Anika discovered a molecule that can selectively bind to the spike protein of the SARS-CoV-2. (discoveryeducation.com)
  • Binding and inhibiting this viral protein would potentially stop the virus entry into the cell, creating a viable drug target. (discoveryeducation.com)
  • The one molecule with the best pharmacological and biological activity towards the spike protein of the SARS-CoV-2 virus was chosen as the lead molecule that can be a potential drug for the effective treatment of COVID-19. (discoveryeducation.com)
  • Our previous work demonstrated that genetic inactivation of the coronavirus exoribonuclease (ExoN) in nonstructural protein 14 (nsp14) of murine hepatitis virus results in a 15-fold decrease in replication fidelity. (jcvi.org)
  • and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine. (moneycontrol.com)
  • The D614G variant carries a mutation in the spike protein that makes it easier for the virus to dock onto human cells. (unibe.ch)
  • The British virus, for example, is known to have not just one but often more than 14 mutations, eight of which occur in the spike protein. (unibe.ch)
  • Think of mRNA as an instruction manual for your body on how to make a specific protein - in this case, a small part of the "spike" protein that appears on the virus' surface. (vcuhealth.org)
  • ABP 300 works by binding the receptor-binding domain of the SARS-CoV-2 spike protein to block viral interaction with angiotensin-converting enzyme 2 (ACE2) receptors. (scienceboard.net)
  • Antibodies are Y-shaped proteins that can bind to special points on foreign substances, such as small protein fragments from a virus. (liu.se)
  • Is your own immune system attacking your vital organs because they now contain toxic virus-mimicking spike protein prions inside them? (shtfplan.com)
Corona Virus2
  • In my previous posts warning about the need to prepare for the Corona virus, my greatest concern has not been the risk of getting ill, but the risk of a society that panics over the virus. (latterdaysaintmag.com)
  • Does it kill Corona Virus? (turnontheblue.com)
Antibodies13
  • Recently, SARS-CoV-like viruses were isolated in Himalayan palm civets and racoon dogs in a retail live animal market in Guangdong Province, southern China ( 6 ), and some of the animals tested had antibodies to SARS-CoV-like virus. (cdc.gov)
  • Specific antibodies for SARS-CoV and SARS-CoV-like virus were tested by using immunofluorescence (IF) assay at 1:10 dilution on FRhK-4 cells infected with either a human SARS-CoV strain (GZ50) ( 5 ) or an animal SARS-CoV-like virus (SZ16) ( 6 ), as reported ( 1 ). (cdc.gov)
  • Seventeen (1.8%) archived samples from healthy adults showed IF antibodies against the human virus, animal virus, or both (titer range 1:20 to 1:1,280) and were confirmed by serum neutralization assay. (cdc.gov)
  • Abbott also developed separate lab-based serology blood tests to detect IgM and IgG antibodies that identify if a person has been previously exposed to the virus that causes COVID. (abbott.com)
  • It will provide a better understanding of the virus, including how long antibodies stay in the body. (abbott.com)
  • It might also tell us whether SARS-CoV-2 can hijack antibodies - which usually help you fight off viruses - to instead help it infect more of your cells and make you sicker. (rochester.edu)
  • During this primary immune response , immune cells encounter spike proteins and, as a defense, they produce antibodies, "memory" cells and T-cells that can kill infected cells to prevent the virus from multiplying. (springfieldnewssun.com)
  • The Division for Clinical Microbiology at Region Östergötland asked whether we could help to develop analysis methods that examine the functional properties of the antibodies that incapacitate viruses", says Jorma Hinkula, professor in the Department of Biomedical and Clinical Sciences (BKV). (liu.se)
  • Some antibodies, known as neutralising antibodies, can also block the ability of the virus to infect new cells. (liu.se)
  • In some wells, the cells (purple) have been protected against the virus by antibodies and thus survived. (liu.se)
  • If neutralising antibodies are present in the blood, they will bind to the virus and incapacitate it. (liu.se)
  • If protective antibodies are not present, the virus will infect the cells and kill them. (liu.se)
  • This analysis is designed to detect antibodies in the blood of a person, but not to determine whether the antibody can neutralise the virus. (liu.se)
Influenza5
  • a test for the exposure to COVID-19 (SARS-CoV-2) not any old virus, such as the yearly influenza. (veteranstoday.com)
  • The tests being used now do distinguish between the COVID-19 virus and the common influenza virus. (veteranstoday.com)
  • Presenters from the Centers for Disease and Prevention (CDC) will review the most up to date guidance on clinical testing for influenza, including situations when influenza and SARS-CoV-2 are co-circulating in a community or other setting. (cdc.gov)
  • Describe clinical test ordering and utilization for seasonal influenza in the context of SARS-CoV-2 co-circulation. (cdc.gov)
  • Adding fuel to the fire is the fact that RSV isn't the only respiratory virus making the rounds - along with COVID, influenza cases are "growing like wildfire," says Piedra, which is creating a 'tripledemic. (yahoo.com)
Particles3
  • You can catch the SARS virus if you breathe in or touch these particles. (medlineplus.gov)
  • The virus spreads mainly from person to person through respiratory droplets and small particles produced when an infected person coughs, sneezes, or talks. (cdc.gov)
  • In the workplace, workers may encounter asymptomatic, pre-symptomatic, and symptomatic individuals who are infected with SARS-CoV-2 and may expel airborne particles containing the virus. (cdc.gov)
Antibody5
  • For sera positive for anti-SARS-CoV or anti-SARS-CoV-like virus, the antibody titer was further determined by serial titration. (cdc.gov)
  • An additional six samples were IF-antibody positive at a 1:10 dilution to either animal or human viruses, but they were negative in neutralization assay and were treated as negative. (cdc.gov)
  • SINGAPORE - She is not just an infectious diseases doctor, but also the leader of one of the latest clinical trials of a Covid-19 antibody to treat patients with the virus. (cgh.com.sg)
  • The monoclonal antibody will block the Sars-CoV-2 virus from gaining entry into cells. (cgh.com.sg)
  • As there has been no effective treatment for the virus so far, this antibody could be used to treat patients with Covid-19 if proven to be effective. (cgh.com.sg)
Vaccine6
  • We devel- oped a model of within-host SARS-CoV-2 dynamics, applied it to virtual patient populations and, invoking the NAb responses above, predicted vaccine efficacies. (ebi.ac.uk)
  • Here, a clinical-stage vaccine candidate comprising a SARS-CoV-2 receptor binding domain-hepatitis B surface antigen virus-like particle elicited protective immunity in cynomolgus macaques. (nih.gov)
  • Dr. Gregory Poland , an infectious diseases expert and director of Mayo Clinic's Vaccine Research Group , explains what soap does to SARS-CoV-2, and other viruses and bacteria. (mayoclinic.org)
  • With representatives from 32 GVN CoEs in 13 countries, the GVN SARS-CoV-2 Task Force meets virtually bimonthly to monthly to share latest research findings and to discuss diagnostics, serological tests and vaccine development. (gvn.org)
  • The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine. (moneycontrol.com)
  • The Johnson & Johnson vaccine gives DNA instructions inside the coat of a different virus, called a viral vector . (springfieldnewssun.com)
Fungi1
  • Diseases that move through animal bites or scratches include bacteria like Bartonella that cause cat scratch fever, viruses that cause rabies, or diseases like ringworm that are caused from fungi. (cdc.gov)
20194
  • Right now, the severity of this new virus, known as 2019-nCoV, is somewhat unclear. (livescience.com)
  • But almost seventy years later, I find myself wondering the same thing about our population at large with respect to the SARS-CoV-2 virus that's been afflicting us over and over and over again since late 2019. (tallandtruetales.blog)
  • Coronavirus disease 2019 (COVID-19) is a respiratory illness caused by the virus SARS-CoV-2. (cdc.gov)
  • The virus has been named "SARS-CoV-2," and the disease it causes has been named "Coronavirus Disease 2019" (COVID-19). (fda.gov)
Genetic8
  • We conducted a comprehensive study in the UK biobank linking germline genetic variation and gene expression with 28 antigens for 16 viruses in 7924 subjects. (medrxiv.org)
  • We also observe that genetic determinants of ACE2 expression may influence SARS-CoV-2 susceptibility. (medrxiv.org)
  • The results define a novel genetic and bioinformatics model for introduction and identification of multi-allelic mutations in replication competent viruses that will be powerful tools for testing the effects of decreased fidelity and increased quasispecies diversity on viral replication, pathogenesis, and evolution. (jcvi.org)
  • Hence, we spent considerable effort developing a robust and sensitive test that can catch the viruses even when they change their genetic sequences. (contagionlive.com)
  • When the virus or a variant is detected, the Cas12 enzyme becomes hyper-activated and begins snipping away detectable genetic material in the sample, including a molecule tagged with a fluorescent dye that is added to the reaction mix. (contagionlive.com)
  • Genetic analysis and epidemiologic studies suggest that SARS coronavirus (CoV) was introduced into humans not long ago. (cdc.gov)
  • Viruses like these evolve their genetic codes over time through mutations or recombination during replication of their structure, and COVID-19 is no exception. (tallandtruetales.blog)
  • Monitoring for genetic changes in the virus allows us to understand better the potential impact of the mutations. (gnb.ca)
Spike1
  • TMPRSS2 also acts on the S2 subunit of the spike glycoprotein, causing an irreversible conformational change, activating it, and facilitating fusion of the virus to the cell membrane. (cebm.net)
Nucleic-acid3
  • As of 0.00am, October 7, the CHP was investigating 3 983 additional locally acquired cases that tested positive for the SARS-CoV-2 virus, comprising 1 046 cases that tested positive by nucleic acid tests (524 confirmed cases, 447 asymptomatic cases and 75 cases with pending status) and 2 937 cases that tested positive by rapid antigen tests (RATs) in the past 24 hours. (gov.hk)
  • Hong Kong has recorded a total of 959 183 and 832 841 cases that have tested positive by nucleic acid tests and RATs respectively for the SARS-CoV-2 virus so far. (gov.hk)
  • Our latest RUO kit, the Luna ® SARS-CoV-2 RT-qPCR Multiplex Assay Kit , enables high throughput workflows for real-time detection of SARS-CoV-2 nucleic acid using hydrolysis probes. (neb.com)
Wuhan1
  • and these medical doctors can't seem to explain it away, certainly never pointing the finger at the clot shots, even though scientific evidence does point to the Wuhan virus injections. (shtfplan.com)
Outbreaks3
  • Public health policies were effective at controlling outbreaks of SARS. (medlineplus.gov)
  • Mouth caps for protection from virus and bacteria outbreaks. (gasmask.nl)
  • During past viral outbreaks, researchers rushed to patent genomic sequences of the viruses as they were discovered, leading to disputes and delays in research coordination. (typepad.com)
Infects2
  • Building on his work on the rabies virus and its use of a network of neurons to travel to the brain, Hervé Borhey and his team, notably Guilherme Dias de Melo, sought to discover whether SARS CoV-2 infects and also travels along nerve cells. (yourdecommissioningnews.com)
  • Here we review the pharmacology of these drugs and the mechanisms whereby the virus infects cells. (cebm.net)
Exposure6
  • Portable air cleaners and residential exposure to SARS-CoV-2 aerosols: a real-world study. (cdc.gov)
  • More work is needed to better understand the possible production of SARS-CoV-2 aerosols by toilet flushing, the size distribution of the aerosol, the infectivity of the virus in the aerosol, and the risk that exposure to these aerosols may pose to healthcare workers and others. (cdc.gov)
  • Which engineering control methods are most effective to prevent SARS-CoV-2 exposure through droplet, fomite and short-range aerosol routes? (cdc.gov)
  • Transparent barriers between workers and customers are being widely deployed to reduce the risk of transmission of SARS-CoV-2, but research is needed on the degree of protection provided by these barriers, and especially on the effects of particle size on exposure reduction. (cdc.gov)
  • Do ventilation systems contribute to the dissemination and subsequent exposure to aerosols containing SARS-CoV-2? (cdc.gov)
  • The value of the extended agreement is $205m and is contingent on AZD7442 receiving Food and Drug Administration Emergency Use Authorisation in post-exposure prophylaxis - the ability to prevent COVID-19 in people who have confirmed exposure to the SARS-CoV-2 virus. (cision.com)
Epidemic6
  • Touching contaminated objects, known as fomite transmission, was suspected during the 2003 SARS-CoV-1 epidemic and analysis of a nosocomial SARS57 CoV-1 superspreading event concluded that touching contaminated objects (fomites) played a significant role(2). (epicos.com)
  • When you claim the grand death total from the SARS "epidemic," worldwide, is 800 out of seven billion, and you can't even prove those 800 died from the "SARS virus," do you, the World Health Organization, admit your whole program of epidemic detection is a fraud? (nomorefakenews.com)
  • You keep calling SARS an epidemic forever. (nomorefakenews.com)
  • No, they choose SARS, for which the cause is absent-and they call THAT an epidemic. (nomorefakenews.com)
  • An epidemic of SARS started in 2003 when the virus spread from small mammals to people in China. (medlineplus.gov)
  • According to WHO, during the epidemic, 8436 cases of SARS and more than 900 deaths were registered in 30 countries, with the largest number of victims reported in Mainland China (348 cases) and Hong Kong (298 cases). (bestwritinghelp.org)
Detection3
  • Additionally, depletion of the pattern recognition receptor MDA5, which plays a critical role in SARS-CoV-2 detection and interferon response initiation4, resulted in increased Omicron virus replication in interferon-competent cells. (kent.ac.uk)
  • However, there is no consensus on the best concentration method to allow reliable detection of SARS-CoV-2 in this matrix, considering different laboratory facilities. (bvsalud.org)
  • The analytical sensitivity ( limits of detection and quantification [LoD/LoQ]) of both methods was evaluated using a bovine respiratory syncytial virus (BRSV) as a surrogate. (bvsalud.org)
Omicron7
  • And search more of iStock's library of royalty-free stock images that features SARS-CoV-2 Omicron Variant photos available for quick and easy download. (istockphoto.com)
  • It's a win-win, and it's why everything on iStock is only available royalty-free - including all SARS-CoV-2 Omicron Variant images and footage. (istockphoto.com)
  • From social media ads to billboards, PowerPoint presentations to feature films, you're free to modify, resize and customize every asset on iStock - including all SARS-CoV-2 Omicron Variant images and footage - to fit your projects. (istockphoto.com)
  • We have most recently shown that Omicron variant viruses are less effective at antagonizing the host cell interferon response than Delta variant viruses, which provides a mechanistic explanation for the reduced clinical severity of Omicron disease in individuals without pre-existing adaptive immunity. (kent.ac.uk)
  • Omicron virus replication was attenuated relative to Delta virus in interferon-competent Caco-2 and Calu-3 cells, but not in interferon-deficient Vero cells, and Omicron viruses caused enhanced interferon promoter activity compared to Delta viruses. (kent.ac.uk)
  • The exact molecular reasons for the alleviated interferon response antagonism by Omicron viruses remain to be elucidated. (kent.ac.uk)
  • DOH 7 Program Manager of Emerging and Re-Emerging Infectious Diseases Dr. Van Phillip Baton said XBB.1.5 is the latest subvariant of the Omicron variant of Sars-CoV-2, the virus that causes the coronavirus disease (Covid-19). (sunstar.com.ph)
Strains2
  • The IF-positive serum samples were serially diluted from 1:20 to 1:640 and then mixed with 100 50% tissue culture infective dose (TCID) 50 of the representative human or animal virus strains for a serum neutralization assay. (cdc.gov)
  • In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus ," Pfizer said. (whatreallyhappened.com)
Antigen1
  • P =5.0×10 −15 (MCV), NTN5: P =1.1×10 −9 (BKV), and P2RY13: P =1.1×10 −8 (Epstein-Barr virus nuclear antigen). (medrxiv.org)
Genomic3
  • Yet similar disputes did not occur with respect to the genomic sequence of SARS-CoV-2, the virus responsible for COVID-19. (typepad.com)
  • The lack of patenting of SARS-CoV-2 is likely due the U.S. Supreme Court's 2013 ruling in Association for Molecular Pathology v. Myriad Genetics, which established that naturally occurring genomic sequences are ineligible for patent protection, a decision that has had repercussions around the world. (typepad.com)
  • The spread of SARS-CoV-2 set off an avalanche of genomic sequencing all around the world. (technologyreview.com)
Bacteria and Viruses2
  • This range is called "The Germicidal Range" because it is proven to kill Bacteria and Viruses. (turnontheblue.com)
  • It purifies the air thanks to the negative ions that neutralize pollutants when they come into contact with the wall, fighting molds, bacteria and viruses, including SARS-CoV-2. (orf.at)
Genome8
  • We describe the sequence polymor- hospital, the patient was in a single room with trans- phisms over time among the 9 whole-virus genome mission-based air-handling precautions. (cdc.gov)
  • SPEE3D developed the unique technique to harness copper's proven abilities to eradicate bacteria, yeasts and viruses rapidly on contact by breaking down the cell wall and destroying the genome(1). (epicos.com)
  • Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing. (jcvi.org)
  • Most RNA viruses lack the mechanisms to recognize and correct mutations that arise during genome replication, resulting in quasispecies diversity that is required for pathogenesis and adaptation. (jcvi.org)
  • However, it is not known how viruses encoding large viral RNA genomes such as the Coronaviridae (26 to 32 kb) balance the requirements for genome stability and quasispecies diversity. (jcvi.org)
  • Analysis of complete genome sequences from SARS-ExoN mutant viral clones revealed unique mutation sets in every genome examined from the same round of replication and a total of 100 unique mutations across the genome. (jcvi.org)
  • Investigators behind the study used a reaction mix containing enAsCas12a, a variant of the enzyme Cas12a that acts like a pair of "molecular scissors", and programmed it to snip off segments of the SARS-CoV-2 virus from the rest of its viral genome. (contagionlive.com)
  • The test, named VaNGuard (Variant Nucleotide Guard), has the ability to recognize up to two mutations within the target sites on the SARS-CoV-2 genome so far. (contagionlive.com)
Droplets6
  • Stopping the ability of COVID-19 viral droplets will also stop the spread of any other virus or bacteria that can travel in the air. (veteranstoday.com)
  • When someone with SARS coughs or sneezes, infected droplets spray into the air. (medlineplus.gov)
  • The SARS virus may live on hands, tissues, and other surfaces for up to several hours in these droplets. (medlineplus.gov)
  • While the spread of droplets through close contact caused most of the early SARS cases, SARS might also spread by hands and other objects the droplets has touched. (medlineplus.gov)
  • A recent commentary in Aerosol Science & Technology, " COVID-19 and the Workplace: Research Questions for the Aerosol Science Community , " presents some of the questions surrounding droplets and aerosols containing SARS-CoV-2 and provides suggestions for future research topics. (cdc.gov)
  • COVID - which, like RSV, is spread through droplets from an infected person's mouth or nose when they speak, cough or sneeze - has also made us more conscious of respiratory viruses in general, including better understanding how they spread and how to prevent them. (yahoo.com)
Spreads5
  • More work is needed to determine how easily the virus spreads from person to person, which will be a key issue in understanding the risk of the virus, Messonnier said. (livescience.com)
  • If it were instituted for good reason, we would now be seeing massive numbers of babies all over the world born with microcephaly (smaller heads and brain damage), as the virus spreads. (nomorefakenews.com)
  • The perfect virus easily spreads from host to host. (medscape.com)
  • The rabies virus circulates and spreads along the axons, using the filamentous structure of neurons to travel through the neural network. (yourdecommissioningnews.com)
  • The virus spreads easily in crowded or poorly ventilated indoor settings. (cdc.gov)
Surveillance1
  • Notifiable Diseases Surveillance System: surveillance case coronavirus 2 (SARS-CoV-2), has led to substantial definitions. (cdc.gov)
Pneumonia1
  • In most people with SARS, a chest x-ray or chest CT show pneumonia, which is typical with SARS. (medlineplus.gov)
Mutate1
  • The results of sequencing the virus conducted by the Chinese scientists differ significantly from those obtained by Canadian and American researchers, suggesting that the virus possesses an ability to mutate rapidly. (bestwritinghelp.org)
Aerosols2
  • A few studies have examined aerosols containing SARS-CoV-2. (cdc.gov)
  • Are potentially infectious aerosols produced by toilets containing human waste with SARS-CoV-2? (cdc.gov)
Laboratory7
  • Australian NATA accredited clinical trial speciality laboratory, 360Biolabs, tested the effect of ACTIVAT3D copper on live SARS-CoV-2 in their Physical Containment 3 (PC3) laboratory. (epicos.com)
  • Last week, EPA approved two products, Lysol Disinfectant Spray (EPA Reg No. 777-99) and Lysol Disinfectant Max Cover Mist (EPA Reg No. 777-127), based on laboratory testing that shows the products are effective against SARS-CoV-2. (reckitt.com)
  • These are the first List N products for which the agency has reviewed laboratory testing data and approved label claims against SARS-CoV-2. (reckitt.com)
  • An international team including researchers from Bern has now been able to demonstrate in both the laboratory and in animal models why the D614G variant was able to gain the upper hand over the original SARS-CoV-2 virus. (unibe.ch)
  • The researchers at IVI and in David E. Wentworth's laboratory at the Centers for Disease Control and Prevention in Atlanta (USA) first demonstrated in human cell cultures from the upper respiratory tract, as well as from the nose, that the D614G variant binds more strongly and also replicates faster than the original virus. (unibe.ch)
  • The IVI relies on a cloning technique developed in Bern a year ago, in which SARS-CoV-2 viruses can be exactly reproduced in the laboratory . (unibe.ch)
  • In a high-containment laboratory, they have cultured the SARS-CoV-2 virus from the patient specimens. (liu.se)
Mutations4
  • A recent study conducted by investigators from Nanyang Technological University, in collaboration with NTU Singapore, discusses a diagnostic test that was developed and can detect SARS-CoV-2 even after it has gone through mutations. (contagionlive.com)
  • It is possible to suggest that the SARS virus appeared as the result of mutations of the previously known coronavirus species. (bestwritinghelp.org)
  • How dangerous are new mutations of the SARS-CoV-2 virus? (unibe.ch)
  • When there have been several significant mutations to the virus then it's called a variant. (gnb.ca)
Scientists3
  • The study conducted by the Amrita scientists has found that inhaled Nitric Oxide (iNO) is virucidal and kills SARS-COV-2 virus, apart from preventing its effective attachment to human host cells. (amrita.edu)
  • The creativity of citizen scientists could help researchers design proteins that may be able to fight the SARS-CoV-2 virus. (the-scientist.com)
  • The glut of data on SARS-CoV-2 has allowed scientists to track, in close to real time, how the virus is evolving. (technologyreview.com)
Sequencing3
  • Presenters will also discuss SARS-CoV-2 sequencing applications for public health. (cdc.gov)
  • Discuss the value of SARS-CoV-2 sequencing in public health compared to clinical practice. (cdc.gov)
  • Stel je niet voor dat genetische sequencing wordt uitgevoerd door mensen die door een elektronenmicroscoop rechtstreeks naar een virus kijken en de namen van rijen genen die naast elkaar zitten, zoals auto's op een parkeerplaats in een supermarkt, opschrijven. (wakkeren.nl)
Transmission12
  • Such transmission "raises our level of concern" about the virus, Messonnier said. (livescience.com)
  • Viral tests can also be used as screening tests to reduce the transmission of SARS-CoV-2 by identifying infected persons who need to isolate from others. (cdc.gov)
  • The CHP appeals to the community to keep on maintaining personal hygiene and comply with social distancing measures in order to jointly contain the risk of virus transmission. (gov.hk)
  • However, the Company's three mines are located in municipalities with low or no transmission of the SARS-CoV2 virus. (pressebox.com)
  • In addition, frequent testing is essential for helping to break the transmission of viruses within populations, so we have developed our tests to be rapid and affordable, making them deployable in resource-poor settings. (contagionlive.com)
  • Currently, there is no known SARS transmission anywhere in the world. (medlineplus.gov)
  • Also, it warns that the transmission of the human-to-human mysterious virus may be possible. (planetnews.com)
  • Faculty research instructor in the immunology and microbiology department at Georgetown University, Alexandra Phelan said that its most probably they'll see this spread of virus given that it seems some form of man-to-man transmission. (planetnews.com)
  • How much SARS-CoV-2 aerosol is generated by coughing, sneezing, talking, singing, and breathing, and what are the implications for transmission? (cdc.gov)
  • Research to address these questions will help to better understand the roles of droplet and aerosol transmission of SARS-CoV-2 and inform public health recommendations. (cdc.gov)
  • However, in the case of SARS-CoV-2, the potential for transmission through this route is unclear. (cdc.gov)
  • On the other hand, VOIs influence the transmission and diagnostic of a virus. (sunstar.com.ph)
Surfaces4
  • Geosyntec's approach for disinfection programs includes wipe sampling and testing to identify whether the surfaces in our client's facilities test positive or negative for the virus. (geosyntec.com)
  • This is compared to traditional surfaces like stainless steel and plastic, with recent studies showing that SARS-CoV-2 can survive on these materials for up to three days(2). (epicos.com)
  • And when a new possible-maybe-could-be virus surfaces in China, now, you bring the same researcher who "discovered SARS" out of mothballs, and you put him front and center. (nomorefakenews.com)
  • This radiation is used to kill viruses and bacteria on surfaces that are otherwise difficult to clean, such as phones, tablets, wallets or purses. (wjbf.com)
Prevention2
  • Officials from the Centers for Disease Control and Prevention (CDC) said they had detected the virus - a new type of coronavirus - in a man in Washington state. (livescience.com)
  • An international team involving researchers from the Institute of Virology and Immunology (IVI) of the Federal Food Safety and Veterinary Office BLV and the University of Bern (Switzerland), the Centers for Disease Control and Prevention (USA), and the Friedrich-Loeffler Institute (Germany), has developed an approach that can accurately assess the transmissibility of new virus mutants. (unibe.ch)
Airborne2
  • How much airborne virus is expelled by people? (cdc.gov)
  • Is the airborne virus infectious? (cdc.gov)
Syndrome2
  • A: Karen, I am going to provide you and our subscribers with the best essential oils combination for SARS (Sudden Acute Respiratory Syndrome) as well! (foreverhealthywater.com)
  • It's certainly not a syndrome unless that 'syndrome' is caused by mRNA "technology" creating a new cell syndrome that can't fight off viruses or bacteria anymore. (shtfplan.com)
Immune3
  • Antioxidants may help fight viruses and support the immune system. (medicalnewstoday.com)
  • This is simply because your immune system, heart, and cleansing organs are not being taxed, polluted, and strained by millions of toxic prions that mimic the lab-concocted, gain-of-function SARS-CoV-2 virus. (shtfplan.com)
  • This choice has enabled your immune system to do what it's supposed to do, naturally, and fend off viruses, bacteria, and pathogens. (shtfplan.com)
Replication4
  • In this report, we systematically analyzed the effect of famotidine on viral proteases and virus replication. (nature.com)
  • These results rule out famotidine as a direct-acting inhibitor of SARS-CoV-2 replication and warrant further investigation of its molecular mechanism of action in the context of COVID-19. (nature.com)
  • Together, these studies have raised the prospect of a direct antiviral effect of famotidine on SARS-CoV-2 replication. (nature.com)
  • Further, the limits of replication infidelity during replication of large RNA genomes and how decreased fidelity impacts virus fitness over time are not known. (jcvi.org)
Susceptibility1
  • Additionally, little is known about the efficacy of ultraviolet germicidal irradiation (UVGI) against SARS-CoV-2, including the dose of UVGI required to inactivate the virus and the effects of temperature, humidity and the presence of other organic material on virus susceptibility to UVGI. (cdc.gov)
Reinfection1
  • During the Q&A session, Blaylock asked Fauci about the likelihood of reinfection by the virus once initially infected. (health.mil)
Respiratory viruses5
  • We had nothing to offer it," meaning that respiratory viruses, including RSV, didn't have as many hosts to infect while people stayed home for the most part. (yahoo.com)
  • Piedra agrees, saying that SARS CoV-2 had a "tremendous" impact on the epidemiology of other respiratory viruses. (yahoo.com)
  • It could be because of the nonpharmaceutical interventions that occurred - wearing masks, social distancing, decreasing the amount of gatherings - impacting the incidence of all the other respiratory viruses," including RSV, he says. (yahoo.com)
  • However, as children went back to school, families started traveling again and nonpharmaceutical interventions such as mask wearing were significantly reduced, "We saw basically the uptake of many respiratory viruses," says Piedra. (yahoo.com)
  • Cases of RSV "happened every year before COVID, but because of COVID, it's caused us to be much more aware of respiratory viruses," says Carl. (yahoo.com)
Concentration2
  • Assessment of virus concentration methods for detecting SARS-CoV-2 IN wastewater. (bvsalud.org)
  • This study compares two viral concentration methods , ultracentrifugation (ULT) and skimmed- milk flocculation (SMF), for detecting SARS-CoV-2 in wastewater samples. (bvsalud.org)
Infect1
  • In vitro models taken from human and animal cells showed the neural orientation of the virus, that is, its ability to infect and transmit the neural network. (yourdecommissioningnews.com)
Phylogenetic1
  • Phylogenetic analysis showed that the SARS-CoV-like animal viruses were closely related to the viruses found in humans. (cdc.gov)
Rabies2
  • We assume that this virus, like rabies, travels through the neural network to certain specific areas of the central nervous system and disrupts certain functions. (yourdecommissioningnews.com)
  • A veterinarian, a medical microbiologist, arrived at the Pasteur Institute to take courses in immunology and virology, and then for his Ph.D., and since then has developed this research on Lysaviruses (including rabies virus), and can be transferred to SARS- CoV-2. (yourdecommissioningnews.com)
Protease3
  • docked a library of approved drugs on to the available X-ray crystal structure of the 3-chymotrypsin-like protease (3CL pro ) of SARS-CoV-2, identifying famotidine as one of the drugs likely to act on the protease 8 . (nature.com)
  • Other computational reports have predicted famotidine as an inhibitor of the Papain-like protease (PL pro ), a second SARS-CoV-2 protease 9 . (nature.com)
  • A host transmembrane serine protease, TMPRSS2 , promotes entry of SARS-Cov into cells by two separate mechanisms . (cebm.net)
Variant1
  • In virtually all sentinel animals, the proportion of transmitted SARS-CoV-2 viruses was massively dominated by the D614G variant early on. (unibe.ch)
Coronavirus: How scientists are tracking 8 strains of SARS-CoV-2 virus
Coronavirus: How scientists are tracking 8 strains of SARS-CoV-2 virus (wickedlocal.com)
China says Wuhan pneumonia not Sars, but virus remains unidentified, more people hospitalised | South China Morning Post
China says Wuhan pneumonia not Sars, but virus remains unidentified, more people hospitalised | South China Morning Post (scmp.com)
Browsing by Subject SARS Virus
Browsing by Subject "SARS Virus" (apps.who.int)
Browsing Regional Publications by Subject SARS Virus
Browsing Regional Publications by Subject "SARS Virus" (apps.who.int)
Browsing Health Ministers Meetings (‎HMM)‎ by Subject SARS Virus
Browsing Health Ministers Meetings (‎HMM)‎ by Subject "SARS Virus" (apps.who.int:80)
Browsing 8th Meeting, Apr 2003 by Subject SARS Virus
Browsing 8th Meeting, Apr 2003 by Subject "SARS Virus" (apps.who.int)
Browsing by Subject SARS Virus
Browsing by Subject "SARS Virus" (extranet.who.int)
Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number 10-October...
Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number 10-October... (wwwnc.cdc.gov)
Figure 2 - Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number...
Figure 2 - Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number... (wwwnc.cdc.gov)
Figure 3 - Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number...
Figure 3 - Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number... (wwwnc.cdc.gov)
Figure 1 - Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number...
Figure 1 - Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital - Volume 10, Number... (wwwnc.cdc.gov)
Browsing EB113 by Subject SARS Virus
Browsing EB113 by Subject "SARS Virus" (extranet.who.int)
Browsing Publications by Subject SARS Virus
Browsing Publications by Subject "SARS Virus" (extranet.who.int)
Quatrième rapport de la Commission A : (‎Projet)‎
Quatrième rapport de la Commission A : (‎Projet)‎ (apps.who.int)
Viral Pneumonia Imaging: Practice Essentials, Radiography, Computed Tomography
Viral Pneumonia Imaging: Practice Essentials, Radiography, Computed Tomography (emedicine.medscape.com)
Viral Pneumonia Imaging: Practice Essentials, Radiography, Computed Tomography
Viral Pneumonia Imaging: Practice Essentials, Radiography, Computed Tomography (emedicine.medscape.com)
Basics of COVID-19 | CDC
Basics of COVID-19 | CDC (cdc.gov)
STIKO-Empfehlung für den Herbst; Ärztetag; Herpes-zoster-Risiko
STIKO-Empfehlung für den Herbst; Ärztetag; Herpes-zoster-Risiko (medscape.com)
COVID Plus Flu 'Increases Risk of Mechanical Ventilation and Mortality'
COVID Plus Flu 'Increases Risk of Mechanical Ventilation and Mortality' (medscape.com)
Fewer Deaths in Hospitalized COVID Diabetes Patients on Sitagliptin
Fewer Deaths in Hospitalized COVID Diabetes Patients on Sitagliptin (medscape.com)
Coughing 'Can Spread SARS-CoV-2 Virus Beyond Two Metres'
Coughing 'Can Spread SARS-CoV-2 Virus Beyond Two Metres' (medscape.com)
New SARS-Like Virus Can Probably Pass Person-to-Person
New SARS-Like Virus Can Probably Pass Person-to-Person (medscape.com)
New Global Registry Investigates COVID-19 and New-Onset Diabetes
New Global Registry Investigates COVID-19 and New-Onset Diabetes (medscape.com)
COVID-19 : à Marseille, un concert-test pensé comme un essai clinique
COVID-19 : à Marseille, un concert-test pensé comme un essai clinique (medscape.com)
New Coronavirus Stable for Hours on Surfaces | NIH: National Institute of Allergy and Infectious Diseases
New Coronavirus Stable for Hours on Surfaces | NIH: National Institute of Allergy and Infectious Diseases (niaid.nih.gov)
NIDCR-Supported RADx Awards | National Institute of Dental and Craniofacial Research
NIDCR-Supported RADx Awards | National Institute of Dental and Craniofacial Research (nidcr.nih.gov)
Diabetes, CVD Tied to Worse Prognosis for COVID-19 Infection
Diabetes, CVD Tied to Worse Prognosis for COVID-19 Infection (medscape.com)
Cas de ré-infection et mutations du virus SARS-CoV-2 : quelles implications ?
Cas de ré-infection et mutations du virus SARS-CoV-2 : quelles implications ? (medscape.com)
Specter of SARS Weighs on CDC as MERS Virus Lands in U.S.
Specter of SARS Weighs on CDC as MERS Virus Lands in U.S. (medscape.com)
Placenta lacks major molecules used by SARS-CoV-2 virus to cause infection | National Institutes of Health (NIH)
Placenta lacks major molecules used by SARS-CoV-2 virus to cause infection | National Institutes of Health (NIH) (nih.gov)