The vein which drains the foot and leg.
The vessels carrying blood away from the capillary beds.
Enlarged and tortuous VEINS.
The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.
Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.
Obstruction of flow in biological or prosthetic vascular grafts.
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.
Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.
The procedure of removing TISSUES, organs, or specimens from DONORS for reuse, such as TRANSPLANTATION.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
The degree to which BLOOD VESSELS are not blocked or obstructed.
The veins that return the oxygenated blood from the lungs to the left atrium of the heart.
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.
Operative procedures for the treatment of vascular disorders.
The inferior part of the lower extremity between the KNEE and the ANKLE.
The use of photothermal effects of LASERS to coagulate, incise, vaporize, resect, dissect, or resurface tissue.
A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.
Venous vessels in the umbilical cord. They carry oxygenated, nutrient-rich blood from the mother to the FETUS via the PLACENTA. In humans, there is normally one umbilical vein.
Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein.
Short thick veins which return blood from the kidneys to the vena cava.
Extravasation of blood into the skin, resulting in a nonelevated, rounded or irregular, blue or purplish patch, larger than a petechia.
Treatment of varicose veins, hemorrhoids, gastric and esophageal varices, and peptic ulcer hemorrhage by injection or infusion of chemical agents which cause localized thrombosis and eventual fibrosis and obliteration of the vessels.
A technique utilizing a laser coupled to a catheter which is used in the dilatation of occluded blood vessels. This includes laser thermal angioplasty where the laser energy heats up a metal tip, and direct laser angioplasty where the laser energy directly ablates the occlusion. One form of the latter approach uses an EXCIMER LASER which creates microscopically precise cuts without thermal injury. When laser angioplasty is performed in combination with balloon angioplasty it is called laser-assisted balloon angioplasty (ANGIOPLASTY, BALLOON, LASER-ASSISTED).
Surgical insertion of BLOOD VESSEL PROSTHESES, or transplanted BLOOD VESSELS, or other biological material to repair injured or diseased blood vessels.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.
Veins which drain the liver.
Flaps within the VEINS that allow the blood to flow only in one direction. They are usually in the medium size veins that carry blood to the heart against gravity.
Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.
The main artery of the thigh, a continuation of the external iliac artery.
Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE.
The nonstriated involuntary muscle tissue of blood vessels.
A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
Endoscopic examination, therapy or surgery performed on the interior of blood vessels.
The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.
Elements of limited time intervals, contributing to particular results or situations.
The continuation of the axillary vein which follows the subclavian artery and then joins the internal jugular vein to form the brachiocephalic vein.
The venous trunk of the upper limb; a continuation of the basilar and brachial veins running from the lower border of the teres major muscle to the outer border of the first rib where it becomes the subclavian vein.
Vein formed by the union (at the hilus of the spleen) of several small veins from the stomach, pancreas, spleen and mesentery.
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles, mammary gland and the axillary aspect of the chest wall.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Veins draining the cerebrum.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and foot. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot.
Central retinal vein and its tributaries. It runs a short course within the optic nerve and then leaves and empties into the superior ophthalmic vein or cavernous sinus.
The formation or presence of a blood clot (THROMBUS) within a vein.
A vein which arises from the right ascending lumbar vein or the vena cava, enters the thorax through the aortic orifice in the diaphragm, and terminates in the superior vena cava.
Large veins on either side of the root of the neck formed by the junction of the internal jugular and subclavian veins. They drain blood from the head, neck, and upper extremities, and unite to form the superior vena cava.
Skin breakdown or ulceration caused by VARICOSE VEINS in which there is too much hydrostatic pressure in the superficial venous system of the leg. Venous hypertension leads to increased pressure in the capillary bed, transudation of fluid and proteins into the interstitial space, altering blood flow and supply of nutrients to the skin and subcutaneous tissues, and eventual ulceration.
Inflammation of a vein, often a vein in the leg. Phlebitis associated with a blood clot is called (THROMBOPHLEBITIS).
Drugs used to cause constriction of the blood vessels.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.
The external junctural region between the lower part of the abdomen and the thigh.
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
Application of a ligature to tie a vessel or strangulate a part.
Radiographic visualization or recording of a vein after the injection of contrast medium.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.
The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.
Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Vascular filters or occlusive devices that provide mechanical protection of the distal end organ from blood clots or EMBOLISM-causing debri dislodged during ENDOVASCULAR PROCEDURES.
The portion of the leg in humans and other animals found between the HIP and KNEE.
A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
The return of a sign, symptom, or disease after a remission.
An alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Transplantation of an individual's own tissue from one site to another site.
The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
The condition of an anatomical structure's being constricted beyond normal dimensions.
The tunnel in the lower anterior ABDOMINAL WALL through which the SPERMATIC CORD, in the male; ROUND LIGAMENT, in the female; nerves; and vessels pass. Its internal end is at the deep inguinal ring and its external end is at the superficial inguinal ring.
The vessels carrying blood away from the heart.
Inflammation of a vein associated with a blood clot (THROMBUS).
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.
Subjective cutaneous sensations (e.g., cold, warmth, tingling, pressure, etc.) that are experienced spontaneously in the absence of stimulation.
Formation and development of a thrombus or blood clot in the blood vessel.
Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)
Layers of connective tissue of variable thickness. The superficial fascia is found immediately below the skin; the deep fascia invests MUSCLES, nerves, and other organs.
Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.
Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.
A vasoconstrictor found in ergot of Central Europe. It is a serotonin agonist that has been used as an oxytocic agent and in the treatment of MIGRAINE DISORDERS.
A series of structurally-related alkaloids containing the ergotaman backbone structure.
Cell-surface proteins that bind SEROTONIN and trigger intracellular changes which influence the behavior of cells. Several types of serotonin receptors have been recognized which differ in their pharmacology, molecular biology, and mode of action.
Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.

Detection of Chlamydia pneumoniae but not cytomegalovirus in occluded saphenous vein coronary artery bypass grafts. (1/1721)

BACKGROUND: A causal relation between atherosclerosis and chronic infection with Chlamydia pneumoniae and/or cytomegalovirus (CMV) has been suggested. Whether the unresolved problem of venous coronary artery bypass graft occlusion is related to infection with C pneumoniae and/or CMV has not been addressed. METHODS AND RESUTLS: Thirty-eight occluded coronary artery vein grafts and 20 native saphenous veins were examined. Detection of C pneumoniae DNA was performed by use of nested polymerase chain reaction (PCR). Homogenisates from the specimen were cultured for identification of viable C pneumoniae. Both conventional PCR and quantitative PCR for detection of CMV DNA were applied. Differential pathological changes (degree of inflammation, smooth muscle cell proliferation [MIB-1]) were determined and correlated to the detection of both microorganisms. C pneumoniae DNA could be detected in 25% of occluded vein grafts. Viable C pneumoniae was recovered from 16% of occluded vein grafts. Except for 1 native saphenous vein, all control vessels were negative for both C pneumoniae detection and culture. All pathological and control specimens were negative for CMV DNA detection. Pathological changes did not correlate with C pneumoniae detection. CONCLUSIONS: Occluded aorto-coronary venous grafts harbor C pneumoniae but not CMV. The detection of C pneumoniae in occluded vein grafts warrants further investigation.  (+info)

The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation. (2/1721)

1. Arachidonic acid (0.01-1 microM) induced relaxation of precontracted rings of rabbit saphenous vein, which was counteracted by contraction at concentrations higher than 1 microM. Concentrations higher than 1 microM were required to induce dose-dependent contraction of vena cava and thoracic aorta from the same animals. 2. Pretreatment with a TP receptor antagonist (GR32191B or SQ29548, 3 microM) potentiated the relaxant effect in the saphenous vein, revealed a vasorelaxant component in the vena cava response and did not affect the response of the aorta. 3. Removal of the endothelium from the venous rings, caused a 10 fold rightward shift in the concentration-relaxation curves to arachidonic acid. Whether or not the endothelium was present, the arachidonic acid-induced relaxations were prevented by indomethacin (10 microM) pretreatment. 4. In the saphenous vein, PGE2 was respectively a 50 and 100 fold more potent relaxant prostaglandin than PGI2 and PGD2. Pretreatment with the EP4 receptor antagonist, AH23848B, shifted the concentration-relaxation curves of this tissue to arachidonic acid in a dose-dependent manner. 5. In the presence of 1 microM arachidonic acid, venous rings produced 8-10 fold more PGE2 than did aorta whereas 6keto-PGF1alpha and TXB2 productions remained comparable. 6. Intact rings of saphenous vein relaxed in response to A23187. Pretreatment with L-NAME (100 microM) or indomethacin (10 microM) reduced this response by 50% whereas concomitant pretreatment totally suppressed it. After endothelium removal, the remaining relaxing response to A23187 was prevented by indomethacin but not affected by L-NAME. 7. We conclude that stimulation of the cyclo-oxygenase pathway by arachidonic acid induced endothelium-dependent, PGE2/EP4 mediated relaxation of the rabbit saphenous vein. This process might participate in the A23187-induced relaxation of the saphenous vein and account for a relaxing component in the response of the vena cava to arachidonic acid. It was not observed in thoracic aorta because of the lack of a vasodilatory receptor and/or the poorer ability of this tissue than veins to produce PGE2.  (+info)

Arterial flow conditions downregulate thrombomodulin on saphenous vein endothelium. (3/1721)

BACKGROUND: The antithrombogenic properties of venous endothelium may be attenuated when vein is implanted in the arterial circulation. Such changes may facilitate thrombosis, which is the final common pathway for saphenous vein arterial bypass graft occlusion. METHODS AND RESULTS: Using human saphenous vein in a validated ex vivo flow circuit, we investigated (1) the possibility that arterial flow conditions (mean pressure, 100 mm Hg, 90 cpm, approximately 200 mL/min) alter the concentration of proteins involved in regulating thrombosis at the vessel wall and (2) the influence of ion channel blockade on such effects. Concentrations of thrombomodulin and tissue factor were quantified by Western blotting (ratio of von Willebrand factor staining) and immunohistochemistry (as a percentage of CD31-staining area). Thrombomodulin concentrations after 90 minutes of venous and arterial flow conditions were quantified by immunostaining (68.9+/-4.8% and 41.0+/-3.0% CD31, respectively; P<0.01) and by Western blotting (1.35+/-0.20 and 0. 15+/-0.03 ratio of von Willebrand factor, respectively; P<0.01). The ability of endothelial cells to generate activated protein C also decreased from 62+/-14 to 19+/-10 ng. min-1. 1000 cells-1 (P=0.01). The significant reduction in thrombomodulin was attenuated if calcium was removed from the perfusate but not by external vein stenting. Inclusion in the vein perfusate of drugs that reduce calcium entry (including Gd3+, to block stretch-activated ion channels, and nifedipine) abolished the reduction in thrombomodulin concentration observed after arterial flow conditions. In freshly excised vein, negligible concentrations of tissue factor were detected on the endothelium and concentrations did not increase after 90 minutes of arterial flow conditions, although the inclusion of nifedipine caused the immunostaining to increase from 3.0+/-0.4% to 8.5+/-0.7% CD31 (P<0.02). CONCLUSIONS: In saphenous vein endothelium exposed to arterial flow conditions, there is rapid downregulation of thrombomodulin, sufficient to limit protein C activation, by a calcium-dependent mechanism.  (+info)

Venous ulceration and continuous flow in the long saphenous vein. (4/1721)

OBJECTIVE: To determine the clinical significance of continuous flow in the long saphenous vein in limbs with venous ulceration. DESIGN: Retrospective review. PATIENTS AND METHODS: Review of 1608 consecutive limbs undergoing colour duplex scanning for venous disease over a 43 month period. RESULTS: Continuous flow in the long saphenous vein is seen in 8% of limbs with venous ulceration and in 37% of limbs with deep venous obstruction. Sixty-six per cent of ulcerated limbs with continuous flow in the long saphenous vein had deep venous obstruction, 27% had deep venous reflux with cellulitis and 7% had lymphoedema in addition to venous ulceration. CONCLUSION: Continuous flow in the long saphenous vein in patients with venous ulceration should alert the clinician to the possibility of deep venous obstruction. Such limbs should be treated by compression bandaging with extreme caution.  (+info)

Isolated femoropopliteal bypass graft for limb salvage after failed tibial reconstruction: a viable alternative to amputation. (5/1721)

PURPOSE: Femoropopliteal bypass grafting procedures performed to isolated popliteal arteries after failure of a previous tibial reconstruction were studied. The results were compared with those of a study of primary isolated femoropopliteal bypass grafts (IFPBs). METHODS: IFPBs were only constructed if the uninvolved or patent popliteal segment measured at least 7 cm in length and had at least one major collateral supplying the calf. When IFPB was performed for ischemic lesions, these lesions were usually limited to the digits or small portions of the foot. Forty-seven polytetrafluoroethylene grafts and three autogenous reversed saphenous vein grafts were used. RESULTS: Ankle brachial pressure index (ABI) increased after bypass grafting by a mean of 0.46. Three-year primary life table patency and limb-salvage rates for primary IFPBs were 73% and 86%, respectively. All eight IFPBs performed after failed tibial bypass grafts remained patent for 2 to 44 months, with patients having viable, healed feet. CONCLUSION: In the presence of a suitable popliteal artery and limited tissue necrosis, IFPB can have acceptable patency and limb-salvage rates, even when a polytetrafluoroethylene graft is used. Secondary IFPB can be used to achieve limb salvage after failed tibial bypass grafting.  (+info)

Superficial femoral eversion endarterectomy combined with a vein segment as a composite artery-vein bypass graft for infrainguinal arterial reconstruction. (6/1721)

OBJECTIVE: The purpose of this study was to determine the results of composite artery-vein bypass grafting for infrainguinal arterial reconstruction. METHODS: This study was designed as a retrospective case series in two tertiary referral centers. Forty-eight of 51 patients underwent the procedure of interest for the treatment of ischemic skin lesions (n = 42), rest pain (n = 3), disabling claudication (n = 1), and infected prosthesis (n = 2). The intervention used was infrainguinal composite artery-vein bypass grafting to popliteal (n = 18) and infrapopliteal (n = 30) arteries, with an occluded segment of the superficial femoral artery prepared with eversion endarterectomy and an autogenous vein conduit harvested from greater saphenous veins (n = 43), arm veins (n = 3), and lesser saphenous veins (n = 2). The main outcome measures, primary graft patency rates, foot salvage rates, and patient survival rates, were described by means of the life-table method for a mean follow-up time of 15.5 months. RESULTS: The cumulative loss during the follow-up period was 6% and 24% at 6 and 12 months, respectively. The primary graft patency rates, the foot salvage rates, and the patient survival rates for patients with popliteal grafts were 60.0% +/- 9.07%, 75.7% +/- 9.18%, and 93.5% +/- 6.03%, respectively, at 1 month; 53.7% +/- 11.85%, 68.9% +/- 12.47%, and 85. 0% +/- 9.92% at 1 year; and 46.7% +/- 18.19%, 68.9% +/- 20.54%, and 53.1% +/- 17.15% at 5 years. For infrapopliteal grafts, the corresponding estimates were 72.4% +/- 7.06%, 72.9% +/- 6.99%, and 92.7% +/- 4.79% at 1 month; 55.6% +/- 10.70%, 55.4% +/- 10.07%, and 77.9% +/- 9.02% at 1 year; and 33.6% +/- 22.36%, 55.4% +/- 30.20%, and 20.8% +/- 9.89% at 5 years. CONCLUSION: The composite artery-vein bypass graft is a useful autogenous alternative for infrainguinal arterial reconstruction when a vein of the required quality is not available or when the procedure needs to be confined to the affected limb.  (+info)

Mid-term results of endoscopic perforator vein interruption for chronic venous insufficiency: lessons learned from the North American subfascial endoscopic perforator surgery registry. The North American Study Group. (7/1721)

PURPOSE: The safety, feasibility, and early efficacy of subfascial endoscopic perforator surgery (SEPS) for the treatment of chronic venous insufficiency were established in a preliminary report. The long-term clinical outcome and the late complications after SEPS are as yet undetermined. METHODS: The North American Subfascial Endoscopic Perforator Surgery registry collected information on 148 SEPS procedures that were performed in 17 centers in the United States and Canada between August 1, 1993, and February 15, 1996. The data analysis in this study focused on mid-term outcome in 146 patients. RESULTS: One hundred forty-six patients (79 men and 67 women; mean age, 56 years; range, 27 to 87 years) underwent SEPS. One hundred and one patients (69%) had active ulcers (class 6), and 21 (14%) had healed ulcers (class 5). One hundred and three patients (71%) underwent concomitant venous procedures (stripping, 70; high ligation, 17; varicosity avulsion alone, 16). There were no deaths or pulmonary embolisms. One deep venous thrombosis occurred at 2 months. The follow-up periods averaged 24 months (range, 1 to 53 months). Cumulative ulcer healing at 1 year was 88% (median time to healing, 54 days). Concomitant ablation of superficial reflux and lack of deep venous obstruction predicted ulcer healing (P <.05). Clinical score improved from 8.93 to 3.98 at the last follow-up (P <. 0001). Cumulative ulcer recurrence at 1 year was 16% and at 2 years was 28% (standard error, < 10%). Post-thrombotic limbs had a higher 2-year cumulative recurrence rate (46%) than did those limbs with primary valvular incompetence (20%; P <.05). Twenty-eight of the 122 patients (23%) who had class 5 or class 6 ulcers before surgery had an active ulcer at the last follow-up examination. CONCLUSIONS: The interruption of perforators with ablation of superficial reflux is effective in decreasing the symptoms of chronic venous insufficiency and rapidly healing ulcers. Recurrence or new ulcer development, however, is still significant, particularly in post-thrombotic limbs. The reevaluation of the indications for SEPS is warranted because operations in patients without previous deep vein thrombosis are successful but operations in those patients with deep vein thrombosis are less successful. Operations on patients with deep vein occlusion have poor outcomes.  (+info)

Popliteal artery occlusion as a late complication of liquid acrylate embolization for cerebral vascular malformation. (8/1721)

Occlusion of arteriovenous malformations of the brain (BAVMs) by means of an endovascular approach with liquid acrylate glue is an established treatment modality. The specific hazards of this procedure are related to the central nervous system. In the case of unexpectedly rapid polymerization of the cyanoacrylate glue and adhesion of the delivering microcatheter to the BAVM, severing the catheter at the site of vascular access is considered an acceptable and safe management. We present a unique complication related to this technique that has not been described yet. Fragmentation and migration of the microcatheter, originally left in place, had caused popliteal artery occlusion, which required saphenous vein interposition, in a 25-year-old man. Suggestions for avoiding this complication are discussed.  (+info)

TY - JOUR. T1 - N-cadherin-dependent cell-cell contacts promote human saphenous vein smooth muscle cell survival. AU - Koutsouki, Evgenia. AU - Beeching, Cressida A. AU - Slater, Sadie C. AU - Blaschuk, Orest W. AU - Sala-Newby, Graciela B. AU - George, Sarah J. PY - 2005/5. Y1 - 2005/5. N2 - OBJECTIVE: Vascular smooth muscle cell (VSMC) apoptosis is thought to contribute to atherosclerotic plaque instability. Cadherin mediates calcium-dependent homophilic cell-cell contact. We studied the role of N-cadherin in VSMC apoptosis.METHODS AND RESULTS: Human saphenous vein VSMCs were grown in agarose-coated wells to allow cadherin-mediated aggregate formation. Cell death and apoptosis were determined after disruption of cadherins using several approaches (n, or =3 per approach). Calcium removal from culture medium or addition of nonspecific cadherin antagonist peptides significantly decreased aggregate formation and increased cell death by apoptosis (34+/-6% versus 75+/-1% and 19+/-1% versus 40+/-5%, ...
Saphenous Vein Bypass Graft Disease Hardcover Books- Buy Saphenous Vein Bypass Graft Disease Books online at lowest price with Rating & Reviews , Free Shipping*, COD. - Infibeam.com
Coronary artery bypass graft (CABG) surgery is a commonly used revascularization strategy in patients with severe coronary artery disease. Saphenous vein grafts (SVGs) are the most frequently used conduits for this procedure. Unlike arterial grafts, SVGs are particularly susceptible to occlusive thrombosis during the first post-operative year, which exposes patients to increased risks of death, myocardial infarction, and repeat revascularization.. This study is designed to evaluate the effect of antiplatelets (Tirafiban and Prasugrel) on the incidence of early and intermediate graft patency after CABG. Patients will undergo planned cardiac Computed tomographic angiography (CTA) predischarge (at 1 week) and CTA/coronary angiography (CAG) at 6 months to 1 year follow-up. CTA at baseline (predischarge) and follow-up CTA/CAG at 6-12 months after CABG will be used to evaluate graft patency. ...
Percutaneous coronary intervention of degenerated saphenous vein grafts remains relatively high risk when compared to native vessel interventions, despite advances in pharmacotherapy and embolic protection. This article discusses the phenomenon of distal embolization that seems to plague saphenous vein graft interventions, reviews device-based strategies for embolic protection, and offers a perspective on the utility of percutaneous saphenous vein graft intervention in both elective and acute settings.. ...
Primary human endothelial cells have a finite life span in vitro. After 3-4 passages, they tend to de-differentiate and eventually reach senescence. This limits their use in studies of endothelial cell function. To overcome this, we have developed human saphenous vein endothelial cell lines (HSVEC lines). Two cell lines were produced by infection with pZipSVtsA58-U19 which encodes the simian virus 40 large T-antigen, and one cell line was obtained by transfection with pLXSN16E6E7, which encodes the human papillomavirus type 16 E6 and E7 genes. Two of the three HSVEC lines exhibited an extended life span in vitro and retained characteristic endothelial cobblestone morphology. These cell lines expressed the known endothelial markers CD31 and vascular endothelial cadherin, and were able to bind Ulex europaeus lectin I, but they did not retain the expression of von Willebrand factor. Furthermore, one cell line was able to functionally up-regulate the expression of intercellular adhesion molecule-1 ...
Objective: The saphenous vein is the most commonly used graft in coronary artery bypass surgery, since no suitable arterial graft is available. However, the frequency of late graft failure is a cause for research into graft protection. The objective of this study was to investigate the effect of synthetic adhesive cyanoacrylate administration on the saphenous vein graft for preventing vascular damage due to internal pressure on the graft. Methods: In this study we enrolled 20 volunteer subjects who had undergone coronary artery bypass surgery and who had excess saphenous vein grafts. Perivascular cyanoacrylate was administered to one of two saphenous vein grafts explanted from each patient. The other saphenous vein graft from each patient was not treated and was used as the control. A model of the arterial system was created using a saphenous vein cardiopulmonary bypass system. Circulation was maintained at 120 mmHg for 45 minutes. Afterwards, the grafts were subjected to histopathological examination.
TY - JOUR. T1 - A New Treatment Strategy for Saphenous Vein Graft Lesions?. T2 - Letting it Go ∗. AU - Brilakis, Emmanouil S.. AU - Banerjee, Subhash. AU - Burke, M. Nicholas. PY - 2018/5/8. Y1 - 2018/5/8. KW - coronary artery bypass graft surgery. KW - native coronary artery. KW - percutaneous coronary intervention. KW - saphenous vein graft. UR - http://www.scopus.com/inward/record.url?scp=85046542322&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85046542322&partnerID=8YFLogxK. U2 - 10.1016/j.jacc.2018.03.457. DO - 10.1016/j.jacc.2018.03.457. M3 - Editorial. C2 - 29724351. AN - SCOPUS:85046542322. VL - 71. SP - 1983. EP - 1985. JO - Journal of the American College of Cardiology. JF - Journal of the American College of Cardiology. SN - 0735-1097. IS - 18. ER - ...
BackgroundEndovenous radio frequency ablation for small saphenous vein incompetence by and large appears to be superior and safer than conventional open surgery. Small saphenous vein ablation from approximately mid-calf to the point proximally where the small saphenous vein dives into the popliteal
The ubiquity of coronary artery disease and the resultant widespread use of saphenous veins for coronary artery bypass surgery has stimulated considerable interest in the morphologic and pathophysiologic alterations these vessels undergo after implantation. This study was undertaken to determine the ability of intravascular ultrasound to identify and characterize abnormalities in saphenous vein grafts. Ten saphenous vein grafts excised at autopsy and nine saphenous vein segments harvested during coronary artery bypass surgery were examined with intravascular ultrasound imaging, quantitative coronary angiographic techniques and histologic analysis.. Intravascular ultrasound lumen measurements were strongly correlated with quantitative coronary arteriographic measurements (r 0.91, SEE 0.5 mm). Wall thickness was significantly greater in the vein grafts after long-term implantation than in the freshly harvested veins (average thickness 1.4 ± 0.5 vs. 0.7 ± 0.2 mm, p , 0.007); this finding ...
article: Saphenous vein graft interventions: strategies and devices to minimize distal embolization - Minerva Cardioangiologica 2012 April;60(2):157-66 - Minerva Medica - Journals
Autologous saphenous vein continues to be one of the most widely used conduits for myocardial revascularization7 despite its disappointing long-term patency rate, with ≤50% of vein grafts occluded by 10 years after surgery.8 9 Late occlusion appears to result from both medial and neointimal thickening, caused by migration and proliferation of smooth muscle cells, and the late appearance of mature lipid-laden atherosclerotic plaques. These changes can compromise flow directly or promote thrombotic occlusion.1 10 Neither antiplatelet therapy nor avoidance of surgical preparative injury has been shown conclusively to eliminate medial and neointimal thickening in either experimental models or human vein grafts.1 2 8 Vessel wall thickening may be regarded as an intrinsic adaptation of the vein to arterial pressure,1 10 and grafting per se was recently shown to stimulate the production of endogenous growth factors from pig saphenous vein, which may account for the platelet independence of graft wall ...
Dive into the research topics of Treatment of no-reflow in degenerated saphenous vein graft interventions: Comparison of intracoronary verapamil and nitroglycerin. Together they form a unique fingerprint. ...
In this study we investigated to find out one of the best preparation technique by the effect of different solutions on venous morphology for harvested saphenous vein graft for CABG. Saphenous veins harvested from 10 patients were divided into three groups, and saphenous veins were divided to 3 cm segments. Group I was the control group and saphenous vein graft was enlarged by 20 mmHg, in Group II saphenous vein graft put in isotonic sodium chloride for 20 minutes and enlarged by 100 mmHg, and Group III saphenous vein graft was put in nitroprusside for 20 minutes and enlarged by 100 mmHg pressure. All saphenous vein segments were examined under light microscope for endothelial cell deprivation, intimal and medial edema and scored from 0 to 3. Mean scores were collected as datas. In nitroprusside group all scoring datas were better. As a result we found out that nitroprusside was having better protective effect on saphenous vein endothelium ...
TY - JOUR. T1 - Early and midterm patency of the proximal anastomoses of saphenous vein grafts made with a Symmetry Aortic Connector System. AU - Kitamura, Hideki. AU - Okabayashi, Hitoshi. AU - Hanyu, Michiya. AU - Soga, Yoshiharu. AU - Nomoto, Takuya. AU - Johno, Hiroyuki. AU - Nakano, Jota. AU - Matsuo, Takehiko. AU - Kai, Masashi. AU - Umehara, Eitaro. PY - 2005/10/1. Y1 - 2005/10/1. N2 - Objective: The purpose of this study was to investigate (1) the early and midterm patency rates in saphenous vein grafts that were anastomosed with the Symmetry Aortic Connector System (St Jude Medical, Inc, St Paul, Minn) and (2) risk factors for graft occlusion. Methods: Thirty-one patients underwent off-pump coronary artery bypass grafting for proximal saphenous vein graft anastomoses with the aortic connector system. Intraoperative graft flow was studied with transit time flowmetry, and angiography was performed before discharge in 29 cases. Midterm (at least 1 year after the operation) saphenous vein ...
TY - JOUR. T1 - Gender-specific Differences in Great Saphenous Vein Conduit. A Link to Lower Extremity Bypass Outcomes Disparities?. AU - Lagergren, Emily R.. AU - Kempe, Kelly. AU - Craven, Timothy E.. AU - Kornegay, S. Tucker. AU - Garg, Nitin. AU - Velazquez-Ramirez, Gabriela. AU - Hurie, Justin B.. AU - Edwards, Matthew S.. AU - Corriere, Matthew A.. PY - 2017/1/1. Y1 - 2017/1/1. N2 - Background Inferior lower extremity bypass (LEB) outcomes have been reported among women with peripheral arterial disease (PAD), but the mechanisms responsible for this disparity are unknown. Great saphenous vein (GSV) is considered the conduit of choice for LEB; GSV diameter is associated with graft patency and therefore is often used as a criterion for suitability for use as bypass conduit. We hypothesized that gender-based differences in GSV may contribute to LEB outcomes disparities. To explore this hypothesis, we performed a gender-based analysis of GSV anatomic characteristics among patients with PAD who ...
Dr. Mehilli will present the study Long-term Outcomes After Use of Drug-Eluting Stents and Bare-Metal Stents for the Treatment of Saphenous Vein Graft Lesions: Results of the Randomized ISAR-CABG Trial on Monday, April 4 at 10:45 a.m. CDT in the Joint Main Tent: La Nouvelle. The American College of Cardiology (www.cardiosource.org) represents the majority of board certified cardiovascular care professionals through education, research, promotion, development and application of standards and guidelines - and to influence health care policy. ACC.11 is the largest cardiovascular meeting, bringing together cardiologists and cardiovascular specialists to share the newest discoveries in treatment and prevention, while helping the ACC achieve its mission to address and improve issues in cardiovascular medicine ...
There are multiple treatment options for varicose veins. While the initial treatment is medical consisting of compression stockings and medications, new products are ever evolving. One of the newest products available is the venaseal closure system for great saphenous veins. This treatment option does not require the postoperative use of compression stockings and has no risk of heat induced complications.. The venaseal closure system for great saphenous veins is a unique treatment option that uses a bioglue to obstruct and close the great saphenous vein. Traditional radiofrequency ablation can cause skin necrosis and has the potential to damage cutaneous nerves. The venaseal closure system for great saphenous veins does not use any heat. The surgeon will localize the vein using ultrasound. Then, the surgeon will insert the catheter into the vein. The catheter is manipulated to the proximal part of the vein and injected with the bioglue. The surgeon will gradually pull back on the catheter while ...
Within 6 h, shear stress upregulated intercellular adhesion molecule-1 (ICAM-1) (two- to four-fold, P|0.001) and induced matrix metalloproteinase-2 (MMP-2) in cultured human saphenous vein endothelial cells. By 8 h endothelial ICAM-1 levels returned to baseline, with concomitant increase in soluble ICAM-1 (sICAM-1) (P|0.001) and MMP-9 had been induced. Inclusion of a hydroxamate metalloproteinase inhibitor partially reversed the effects on ICAM-1 and sICAM-1 at 8 h, whereas TIMP-1, -2 or -3 had no effect. MMP-9, but not MMP-2, co-immunoprecipitated with ICAM-1. sICAM-1 was processed distal to Arg441, indicating that MMP-9, docking to ICAM-1, contributes to sICAM-1 shedding and attenuation of the shear stress-induced upregulation of ICAM-1.
The great saphenous vein (GSV) forms part of the superficial venous system of the lower limb. Terminology Great saphenous vein is the preferred terminology over other variants such as long saphenous vein (LSV), greater saphenous vein or intern...
BACKGROUND: Externally stenting saphenous vein grafts reduces intimal hyperplasia, improves lumen uniformity and reduces oscillatory shear stress 1 year following surgery. The present study is the first to present the longer-term (4.5 years) performance and biomechanical effects of externally stented saphenous vein grafts. METHODS: Thirty patients previously implanted with the VEST external stent in the randomized, within-patient-controlled VEST I study were followed up for adverse events; 21 of these were available to undergo coronary angiography and intravascular ultrasound. RESULTS: Twenty-one stented and 29 nonstented saphenous vein grafts were evaluated by angiography and ultrasound at 4.5 ± 0.3 years. Vein graft failure rates were comparable between stented and nonstented grafts (30 and 23% respectively; p = 0.42). All failures were apparent at 1 year except for one additional nonstented failure at 4.5 years. In patent vein grafts, Fitzgibbon perfect patency remained significantly higher in the
Aneurysmatic degeneration of saphenous vein coronary artery grafts is a rare complication that generally appears late. Most of these cases are asymptomatic, although they may also be accompanied by angina, heart attack or dyspnea. The suspected diagnosis should be made when a mediastinal mass is discovered in the thoracic x-ray of a patient with a history of coronary revascularization. A computerized tomography and coronary angiography should be performed in order to confirm the diagnosis.. Due to the significant morbidity and mortality risk inherent to the risk of rupture, embolization or heart attack, surgery to remove or exclude the aneurysm should be considered as definitive treatment.. ...
Coronary artery bypass grafting is an effective treatment for myocardial ischaemia and is particularly important in patients with multivessel disease and diabetes. However, up to 40% of saphenous vein grafts will occlude within 10 years of surgery. T
The great saphenous vein (GSV), also long saphenous vein, is the large (subcutaneous) superficial vein of the leg and thigh. The GSV originates from where the dorsal vein of the first digit (the large toe) merges with the dorsal venous arch of the foot. After passing anterior to the medial malleolus (where it often can be visualized and palpated), it runs up the medial side of the leg. At the knee, it runs over the posterior border of the medial epicondyle of the femur bone. The great saphenous vein then courses laterally to lie on the anterior surface of the thigh before entering an opening in the fascia lata called the saphenous opening. It joins with the femoral vein in the region of the femoral triangle at the saphenofemoral junction ...
Define saphenous vein, great. saphenous vein, great synonyms, saphenous vein, great pronunciation, saphenous vein, great translation, English dictionary definition of saphenous vein, great. n. 1. a. Anatomy Any of the membranous tubes that form a branching system and carry blood to the heart from the cells, tissues, and organs of the body. b.
Bypass in the absence of ipsilateral greater saphenous vein: safety and superiority of the contralateral greater saphenous vein. J Vasc Surg. 2002 Jun; 35(6):1085-92 ...
• Autogenous saphenous vein was used preferentially for 92 below-knee bypass procedures (44 femoral-distal popliteal and 48 femoral-distal tibial or peroneal) p
A 73 year old woman presented with angina 22 years after saphenous vein grafts. All three grafts were in excellent condition, with the exception of a severe stenosis in the proximal portion of the circumflex graft (panel A). For elective percutaneous coronary intervention (PCI), a FilterWire distal protection device was deployed in the body of the graft before pre-dilatation with a 2.5 × 15 mm Maverick balloon. Aiming to minimise the risk of distal embolisation, a (self expanding nitinol) Symbiot polymer covered stent (4.0 × 20 mm) was deployed (panel B). These stents require post-inflation to optimise deployment. Following in-stent inflation (4.0 × 15 mm Extensor) a new filling defect (white arrow) was immediately apparent within the stent at its proximal end (panel C). Filling defects (white arrows) were also present within the FilterWire device (black arrows) (panel C). The in-stent debris was presumed to be material extruded from the proximal margin of the covered stent after high ...
The main trunk of the long saphenous vein arises from the medial marginal vein, anteriorly to the medial malleolus. It ascends vertically behind the medial border of the tibia, then behind the medial condyle of the femur to reach the femoral vein below the inguinal ligament.. In addition to the anatomical variants of its junction with the femoral vein, the long saphenous vein is also characterized by the complexity of its accessory and satellite networks.. It is essential to remember that a dilated long saphenous vein, with reflux at the saphenofemoral junction and upper third of the thigh, may be associated with a small (2 mm), competent trunk in the mid-thigh. This vessel, sometimes not detected on ultrasonography, preserves its normal anatomical course along the aponeurosis in the lower third of the thigh, as the reflux persists in an anterior or posterior accessory saphenous yein (Figure 66 left), or an accessory vein parallel to the main trunk (Figure 66 right).. When the accessory vein is ...
Mycotic aneurysms of saphenous vein grafts in coronary artery bypass grafts remain a rare entity with the bulk of global literature being case reports and small series. There is high morbidity and mortality associated with this condition in the peri-operative period. We present our experience with the surgical management of a mycotic aneurysm of a saphenous vein graft 14 years after the original operation.. ...
Background Saphenous vein grafts develop an aggressive atherosclerotic process and the efficacy of drug eluting stents (DES) in treating saphenous vein graft (SVG) lesions has not been convincingly demonstrated. The aim of this study was to review and analyze the current literature for controlled studies comparing DES versus bare metal stents (BMS) for treatment of SVG stenoses. Methodology/Principal Findings We searched several scientific databases and conference proceedings up to March 15, 2010 for controlled studies comparing target vessel revascularization (TVR) between DES and BMS. Summary odds ratios (OR) for the primary endpoint TVR and secondary endpoints infarction, stent thrombosis and death were calculated using random-effect models. A total of 29 studies (3 randomized controlled trials RCT) involving 7549 (202 in RCT) patients were included. The need for target vessel revascularization in the DES group tended to be lower compared to BMS for the 3 RCT (OR 0.50 [0.24-1.00]; p = 0.051) and for
Fifty-five consecutive patients with intermittent resting chest pain persisting more than 24 hours after hospitalization and accompanied by ECG changes representative of ischemia were operated urgently more than one year ago. Recent cases with shorter follow-up are excluded. Twenty-eight patients had single grafts, 23 had double grafts, three had triple grafts, and one a quadruple graft. There were three operative deaths (5%) and one sudden late death (2%). There were six early Mls and three late Mls. Follow-up ranges from 12 to 52 months (mean 24 months) with nine patients followed for four years. Actuarial analysis indicates a projected survival rate of 93% three years postoperative. Twenty-three survivors are Functional Class (FC) I, 19 are FC II, and eight are FC III. Functional class could not be determined in one survivor. Thirty patients had postoperative angiography one week to 32 months postop. 35/51 grafts were patent. Only three patients had no patent grafts. There were no significant ...
OBJECTIVES. To gain insight into the mechanism of stenting in humans and its short- and long-term implications, we studied the vascular wall of saphenous vein aortocoronary bypass grafts after implantation of the Wallstent. BACKGROUND. The implantation of a stent in aortocoronary bypass grafts may provide an alternative solution for revascularization in patients who are poor candidates for reoperation. Because human histopathologic findings after stenting with the Wallstent have not previously been described in detail, we examined graft segments that were surgically retrieved from 10 patients (21 stents) at 3 days to 10 months after implantation of the stent. METHODS. The grafts were examined by a combination of the following techniques: light microscopy, immunocytochemistry and both scanning and transmission electron microscopy. RESULTS. Early observations revealed that large amounts of platelets and leukocytes adhered to the stent wires during the first few days. At 3 months, the wires were ...
The saphenous vein is involved in 99% of all the varicose veins seen in females in Bay Shore. Any condition that causes high pressures in this vein causes the valves to pull apart and leads to engorgement of the saphenous vein.
The saphenous vein is involved in 99% of all the varicose veins seen in females in New City. Any condition that causes high pressures in this vein causes the valves to pull apart and leads to engorgement of the saphenous vein.
Results from a recent investigiation has established that Laser crossectomy of the GSV is a more effective method of preventing secondary anterior accessory great saphenous vein reflux
Bourassa MG, Enjalbert M, Campeau L, Lesperance J. Progression of atherosclerosis in coronary arteries and bypass grafts. Ten years later. Am J Cardiol 1984;53:102C-107C. Johnson WD, Kayser KL, Pednaza PM: Angina pectoris and coronary bypass surgery: Patterns of prevalence and recurrence in 3105 consecutive patients followed upto 11 years. Am Heart J ;108:1190-7. Savage MP, Douglas JS Jr, Fischman DL, Pepine CJ, King SB rd, Werner JA, et al. Stent placement compared with balloon angioplasty for obstructed coronary bypass grafts. N Engl J Med ;337:740 -7. J Ayub Med Coll Abbottabad 2012;24(3-4) http://www.ayubmed.edu.pk/JAMC/24-3/Tariq.pdf Verghese M, Berger PB, Lennon RJ, Gersh BJ, Holmes DR, Jr. Comparison of percutaneous interventions for unstable angina pectoris with and without previous coronary artery bypass grafting. Am J Cardiol 2000;86:931-7. Laird-Meeter K, ten Katen HJ, Brower RW, van den Brand MJ, Serruys PW, Haalebos MM, et al. Angina pectoris, 1 to 10 years after aortocoronary ...
OBJECTIVES: Early saphenous vein graft (SVG) occlusion is typically attributed to technical factors. We aimed at exploring clinical, anatomical, and operative factors associated with the risk of early SVG occlusion (within 12 months postsurgery). METHODS: Published literature in MEDLINE was searched for studies reporting the incidence of early SVG occlusion. Individual patient data (IPD) on early SVG occlusion were used from the SAFINOUS-CABG Consortium. A derivation (n = 1492 patients) and validation (n = 372 patients) cohort were used for model training (with 10-fold cross-validation) and external validation respectively. RESULTS: In aggregate data meta-analysis (48 studies, 41,530 SVGs) the pooled estimate for early SVG occlusion was 11%. The developed IPD model for early SVG occlusion, which included clinical, anatomical, and operative characteristics (age, sex, dyslipidemia, diabetes mellitus, smoking, serum creatinine, endoscopic vein harvesting, use of complex grafts, grafted target vessel, and
TY - JOUR. T1 - Diffusa ectasia e aneurisma focale di un by-pass venoso aorto-coronarico. AU - Lucreziotti, Stefano. AU - Sponzilli, Carlo. AU - Castini, Diego. AU - Salerno, Diego. AU - Bosotti, Laura. AU - Lombardi, Federico. PY - 2007/4. Y1 - 2007/4. N2 - Saphenous vein graft disease is a continuum process which develops from the very early post-surgical period. Although progressive obstruction is the most common feature of SVG disease, severe dilatation with patterns of diffuse ectasia, aneurysm, or pseudoaneurysm may rarely occur. The present article describes a case of an aorto-coronary vein graft presenting an angiographic pattern of diffuse ectasia with a focal aneurysm.. AB - Saphenous vein graft disease is a continuum process which develops from the very early post-surgical period. Although progressive obstruction is the most common feature of SVG disease, severe dilatation with patterns of diffuse ectasia, aneurysm, or pseudoaneurysm may rarely occur. The present article describes a ...
To the editor: I am responding to a statement made by Farry and associates in a recent case report (Development of Atherosclerosis in Saphenous Vein Coronary Bypass Graft, Ann Intern Med 85:478-479, 1976).. The authors state that the occurrence of atherosclerosis in aortocornary saphenous vein bypass grafts had not been described before their report. This is not true; our group in Milwaukee has previously reported several such instances (see references below). ...
The lesser saphenous vein is a venous blood vessel that runs up the length of the leg. It originates from the junction formed between two small veins in the foot, the fifth toes dorsal vein and the dorsal venous arch.
TY - JOUR. T1 - Thapsigargin inhibits smooth muscle cell proliferation and intima formation in human saphenous vein. AU - George, SJ. AU - Angelini, GD. AU - Jeremy, JY. PY - 1997. Y1 - 1997. M3 - Article (Academic Journal). VL - 17. SP - 2500. EP - 2506. JO - Arteriosclerosis, Thrombosis, and Vascular Biology. JF - Arteriosclerosis, Thrombosis, and Vascular Biology. SN - 1079-5642. ER - ...
TY - JOUR. T1 - Contemporary use of embolic protection devices in saphenous vein graft interventions. T2 - Insights from the stenting of saphenous vein grafts trial. AU - Badhey, Neeraj. AU - Lichtenwalter, Christopher. AU - de Lemos, James A. AU - Roesle, Michele. AU - Obel, Owen. AU - Addo, Tayo A. AU - Haagen, Donald. AU - Abdel-Karim, Abdul Rahman. AU - Saeed, Bilal. AU - Bissett, Joseph K.. AU - Sachdeva, Rajesh. AU - Voudris, Vassilios V.. AU - Karyofillis, Panagiotis. AU - Kar, Biswajit. AU - Rossen, James. AU - Fasseas, Panayotis. AU - Berger, Peter B.. AU - Banerjee, Subhash. AU - Brilakis, Emmanouil S. PY - 2010/8/1. Y1 - 2010/8/1. N2 - Background: We sought to evaluate the contemporary use of embolic protection devices (EPDs) in saphenous vein graft (SVG) interventions. Methods: We examined EPD use in the stenting of saphenous vein grafts (SOS) trial, in which 80 patients with 112 lesions in 88 SVGs were randomized to a bare metal stent (39 patients, 43 grafts, and 55 lesions) or ...
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Background: Endoscopic vein harvest (EVH) was introduced in 1996 as an alternative to open vein harvest (OVH) for coronary artery bypass graft (CABG) surgeries utilizing the saphenous vein. EVH has been shown to decrease post operative pain, wound complications, and length of hospital stay. Although EVH has become the preferred method of saphenous vein harvest, the effect of EVH on graft patency has not been well studied. A study published in the New England Journal of Medicine in 2009 concluded that EVH was independently linked to increased morbidity and decreased graft patency. This surprising conclusion was not endorsed by the cardiothoracic community. Much debate about the effect of EVH on graft patency has ensued, however, surgical practice appears to have remained unchanged. The potential harm of EVH must be weighed against its proven benefits in the light of the large number of patients that undergo EVH annually as the predominant mode of saphenous vein harvest Methods: An exhaustive literature
Importance: Observational studies have suggested that the use of radial artery grafts for coronary artery bypass grafting may improve clinical outcomes compared with the use of saphenous vein grafts, but this has not been confirmed in randomized trials.. Objective: To compare clinical outcomes between patients receiving radial artery vs saphenous vein grafts for coronary artery bypass grafting after long-term follow-up.. Design, Setting, and Participants: Patient-level pooled analysis comparing radial artery vs saphenous vein graft in adult patients undergoing isolated coronary artery bypass grafting from 5 countries (Australia, Italy, Serbia, South Korea, and the United Kingdom), with enrollment from 1997 to 2009 and follow-up completed in 2019.. Interventions: Patients were randomized to undergo either radial artery (n = 534) or saphenous vein (n = 502) grafts for coronary artery bypass grafting.. Main Outcomes and Measures: The primary outcome was a composite of death, myocardial infarction, ...
TY - JOUR. T1 - Minimally invasive saphenous vein harvest with the SaphLITE system. AU - O-Yurvati, A. H.. AU - Martin, Adriane K.. AU - Peska, Don. PY - 2005/1/1. Y1 - 2005/1/1. N2 - The method of harvesting the greater saphenous vein (GSV) through a long continuous incision is associated with a number of well-documented wound complications and significant postoperative pain. A randomized trial was developed to examine the outcome of standard harvesting techniques versus a minimally invasive harvesting technique using the SaphLITE system. Two hundred elective coronary artery bypass-graft patients were randomly placed into either a traditional saphenous vein harvest group (control) or a minimally invasive SaphLITE harvest group (study). Postoperative wound complications, patient discomfort, and length of follow-up were studied. Wound complications were greater in the control group compared with the study group (P , 0.025). Patient discomfort was markedly reduced in the study group. The ...
TY - JOUR. T1 - Fate of varicose veins after great saphenous vein stripping alone. AU - Nishibe, T.. AU - Kondo, Y.. AU - Dardik, A.. AU - Muto, A.. AU - Nishibe, M.. PY - 2009/8. Y1 - 2009/8. N2 - Aim. The aim of this study was to observe prospectively the clinical sequelae of varicose veins after great saphenous vein (GSV) stripping alone, and to examine whether spontaneous varicose vein regression or disappearance continued for a long period (,3 years). Methods. Thirty-nine consecutive patients (20 males and 19 females; mean age 57.2), who underwent GSV stripping in Fujita Health University (55 limbs) between November 1, 2002 and December 31, 2003 were enrolled. Results. At four to six weeks, varicose veins spontaneously resolved in 50 limbs (91%), in which subsequent sclerotherapy was not necessary. Five limbs subsequently underwent sclerotherapy for residual varicose veins (5%). At more than three years, 49 limbs (89%) completed the follow-up study. The recurrence after GSV stripping alone ...
The saphenous vein, which runs from the ankle to the groin along the inside of the leg, is commonly used as a graft for people undergoing a CABG surgery. The vein is removed from the leg and reattached to the heart to create a detour around the blocked part of a coronary artery. Following this procedure, many people are prescribed aspirin as a way to increase the chance that the graft procedure will be successful. However, saphenous vein graft failure may still occur in some people, indicating a need to understand why this happens and who might be at risk for graft failure. Thrombin, a protein involved in the blood clotting process, is somehow related to aspirin resistance, abnormalities in blood flow, and cell disruption within the saphenous vein, all factors thought to increase the risk of graft failure. The purpose of this study is to evaluate the likelihood that a burst in thrombin contributes to graft failure in people who have recently undergone a CABG procedure using the saphenous ...
Endovenous Laser Treatment (EVLT®), also known as laser vein ablation, is a minimally-invasive procedure used to treat the great saphenous vein (GSV), small saphenous vein (SSV) and other superficial veins. It uses laser energy applied inside the faulty (or incompetent) vein to seal it shut. The EVLT procedure has been FDA-approved since 2002 and over 100,000 procedures have been performed. Endovenous laser treatment (EVLT) is commonly performed in a physicians office, under local anesthesia, in less than an hour, generally with rapid return to normal activity. Other names for laser vein ablation include endovenous laser ablation of the saphenous vein (ELAS or ELA), endovenous laser therapy (ELT), and endovenous laser vein system (ELVeS).
Endovenous Laser Treatment (EVLT®), also known as laser vein ablation, is a minimally-invasive procedure used to treat the great saphenous vein (GSV), small saphenous vein (SSV) and other superficial veins. It uses laser energy applied inside the faulty (or incompetent) vein to seal it shut. The EVLT procedure has been FDA-approved since 2002 and over 100,000 procedures have been performed. Endovenous laser treatment (EVLT) is commonly performed in a physicians office, under local anesthesia, in less than an hour, generally with rapid return to normal activity. Other names for laser vein ablation include endovenous laser ablation of the saphenous vein (ELAS or ELA), endovenous laser therapy (ELT), and endovenous laser vein system (ELVeS).
TY - JOUR. T1 - Relation of saphenous vein graft obstruction to serum cholesterol levels. AU - Daida, Hiroyuki. AU - Yokoi, Hisashi. AU - Miyano, Hiroshi. AU - Mokuno, Hiroshi. AU - Satoh, Hiroyuki. AU - Kottke, Thomas E.. AU - Hosoda, Yasuyuki. AU - Yamaguchi, Hiroshi. N1 - Copyright: Copyright 2014 Elsevier B.V., All rights reserved.. PY - 1995/1. Y1 - 1995/1. N2 - Objectives. To determine the potential of lipid-lowering therapy to reduce saphenous vein graft obstruction, we retrospectively studied the association between graft obstruction and serum cholesterol levels. Background. Atherosclerosis is the major cause of vein graft obstruction. Approximately 50% of grafts are occluded by 10 years after operation. It remains to be established whether lipid control affects long-term graft survival. Methods. We carried out a retrospective review of all 284 patients who had undergone coronary artery bypass graft surgery at Juntendo University Hospital between 1976 and 1991 and met the following ...
TY - JOUR. T1 - Update of endovenous treatment modalities for insufficient saphenous veins-A review of literature. AU - van Eekeren, Ramon R.J.P.. AU - Boersma, Doeke. AU - de Vries, Jean Paul P.M.. AU - Zeebregts, Clark J.. AU - Reijnen, Michel M.P.J.. PY - 2014/1/1. Y1 - 2014/1/1. N2 - Lower-limb venous insufficiency resulting from saphenous vein incompetence is a common disorder, increasing with age. For decades, surgical stripping of the great saphenous vein has been the gold standard in varicose vein treatment. The desire to optimize outcomes of treatment and reduce surgical trauma has led to the development of endovenous techniques. Today, several endovenous techniques are available to ablate the saphenous vein segments with abnormal vein valve function. In this review, we discuss the techniques, mechanisms of action, outcomes, and complications of all endovenous treatment modalities for the treatment of symptomatic lower-limb varicose veins.. AB - Lower-limb venous insufficiency resulting ...
TY - JOUR. T1 - Aprotinin for coronary bypass operations. T2 - Efficacy, safety, and influence on early saphenous vein graft patency: A multicenter, randomized, double-blind, placebo-controlled study. AU - Lemmer, John H.. AU - Stanford, William. AU - Bonney, Sharon L.. AU - Breen, Jerome F.. AU - Chomka, Eva V.. AU - Eldredge, W. Jay. AU - Holt, William W.. AU - Karp, Robert B.. AU - Laub, Glenn W.. AU - Lipton, Martin J.. AU - Schaff, Hartzell V.. AU - Tatooles, Constantine J.. AU - Rumberger, John A.. PY - 1994/1/1. Y1 - 1994/1/1. N2 - The purpose of this study was to evaluate the efficacy and safety of aprotinin in a U.S. population of patients undergoing coronary artery bypass grafting. Early vein graft patency rates were assessed by ultrafast computed tomography. A total of 216 patients at five centers were randomized to receive either high-dose aprotinin or placebo during the operation; 151 patients underwent primary operation, and 65 underwent repeat procedures. Total blood product ...
1. We investigated the potentiating effect of low concentrations of neuropeptide Y (NPY) on the vasoconstriction induced by transmural nerve stimulation (TNS) and noradrenaline (NA) in human saphenous veins. The effects of (i) endothelium removal; (ii) the addition of the NO pathway precursor L-arginine; (iii) the ET(A)/ET(B) endothelin receptor antagonist Ro 47-0203; (iv) the cyclo-oxygenase inhibitor, indomethacin; (v) the selective thromboxane A2 (TxA2) receptor antagonists Bay u3405 and ifetroban, and (vi) the TxA2 synthase inhibitor, UK 38485, were studied in order to gain information about the mechanisms of NPY-induced potentiation. 2. Contractile response curves for TNS (0.5-8 Hz) and for exogenously administered NA (0.1-3 microM) were obtained in superfused saphenous vein rings. The contractions induced by both TNS and NA at all tested frequencies and concentrations, respectively, were significantly potentiated by 50 nM NPY in endothelium intact veins. Conversely, in endothelium-denuded vessel
TY - JOUR. T1 - Simvastatin attenuates the endothelial pro-thrombotic shift in saphenous vein grafts induced by Advanced glycation endproducts. AU - Spadaccio, Cristiano. AU - De Marco, Federico. AU - Di Domenico, Fabio. AU - Coccia, Raffaella. AU - Lusini, Mario. AU - Barbato, Raffaele. AU - Covino, Elvio. AU - Chello, Massimo. PY - 2014/3. Y1 - 2014/3. N2 - Background Advanced glycation endproducts (AGEs) and its receptors (RAGEs) are heterogeneous signaling proteins associated to diabetes and responsible of endothelial alterations leading to atherosclerosis progression and graft failure. The aim of this study was to investigate the role of statin in reducing AGEs related endothelial damage. Methods Endothelial cell(EC) obtained from leftovers of saphenous vein grafts of non-diabetic patients were incubated with AGEs (2 and 20 μM) and subsequently treated with Simvastatin. Neutrophils (PNM) adherence, ROS production and RAGE and peroxisome proliferator-activated receptors-gamma (PPAR-γ) ...
PURPOSE: To present the immediate and short-term results of our first 60 endovenous laser (EVL) ablation procedures. MATERIALS AND METHODS: Between July 2005 and December 2006, 60 EVL ablations were performed in 36 symptomatic patients (26 females, 1
Technique Summary Resources and references Saphenous vein sampling in other animals All blood sampling techniques in the guinea pig Please read the general principles of blood sampling page before attempting any blood sampling procedure. Technique Sampling from the lateral saphenous vein is a relatively quick method of obtaining blood samples from all strains of guinea pig. It does not require the animal to be warmed. Slides and videos of restraint, shaving and sampling for this technique with mice are available on the websites of the Norwegian Reference Centre for Laboratory Animal Science. Blood is collected from the lateral saphenous vein, which runs dorsally and then laterally over the tarsal joint. Conscious guinea pigs should be restrained either manually or using a restraint tube. This can cause stress and therefore the duration of restraint should be minimised. Where a restraint tube is used, it should be appropriate for the size of the guinea pig. All forms of restraining equipment should be
More than 50% of aortocoronary saphenous vein grafts are occluded 10 years after surgery. Intimal hyperplasia is the initial critical step in the progression toward occlusion. Internal mammary veins, which are physiologically prone to less hydrostatic pressure, may undergo an accelerated progression to intimal hyperplasia and thus be suitable for investigation of the mechanisms of aortocoronary vein graft disease. Six minipigs underwent aortocoronary bypass grafting using standard cardiopulmonary bypass and cardioplegic arrest. Mammary vein were grafted in a reversed manner from ascending aorta to left anterior descending coronary artery (LAD). The proximal LAD was ligated, rendering the anterior left ventricle vein graft-dependent. Minipigs were killed after 4 weeks, and vein grafts were harvested. Histological and immunohistological investigation were performed with respect to morphometric analysis, endothelial damage/dysfunction (v-Willebrand-factor (vWF)), smooth muscle cells (α-smooth actin) and
Background. According to previously published studies, the most frequent localization of vascular lesions responsible for recurrent varicose vein (RVV) development is a previously ligated saphenofemoral junction (SFJ) site. Discovering the background of these lesions would allow the implementation of suitable methods to reduce their incidence and thus RVV development. Material and methods. We examined 240 patients (283 limbs) with RVV after classic surgical treatment of primary lower limb varicose veins. The reasons for varicose vein recurrence were determined with duplex ultrasound examination. Results. Faults of the surgical technique and neovascularization were causes for true recurrence of varicose veins (TRVV) in 87.6% of all limbs with RVV. Incompletely extirpated great saphenous veins (GSV) or small saphenous veins (SSV) were discovered in 25.1% of cases. Stumps with SFJ or SPJ tributaries were found in 76.3% of limbs. Persistent tributaries were present on stumps in 68.5% of cases, ...
Memorial Medical Center (Springfield, IL) Medical Imaging Services Saphenous vein ablation is used to treat venous insufficiency in the leg by ablating the vein using thermal energy.
Are your veins becoming abnormally large? Do they look twisted? If you are experiencing these symptoms on your legs or any other parts of your body, there is a high chance you might have varicose veins. Varicose veins occur when your blood valves leak and creates a pool of blood in your leg veins. As a result, your veins will start to swell up. Many people will experience discomfort or aches in the region, as the vein continues to enlarge and starts to get inflamed. When the symptoms get severe, it is advised to consult your local vein clinic for treatment.. With modern advancements in the medical field, there are now efficient varicose vein treatments that are non-invasive and safe. One of the most effective procedures for treating varicose veins is Endovenous ablation. Endovenous ablation is an image-guided procedure that takes advantage of ultrasound technology to help close the affected vein. This procedure is minimally invasive and is generally safe to perform. However, unlike other ...
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Endovenous laser varicose vein surgery is a procedure that uses heat from a laser to reduce varicose veins. Varicose veins are swollen, bulging veins that often happen on the thighs or calves. A laser is a device that sends a thin beam of radiation in the form of light.
HistoryA 48-year-old man underwent three-vessel aortocoronary bypass graft for unstable angina and high-grade occlusive coronary artery disease. Postoperatively
form of light.. Laser surgery closes and shrinks the varicose vein and causes scar tissue within the vessel. This seals off the vein. Blood then flows through other nearby veins instead.. Your healthcare provider may suggest laser surgery if your varicose veins are sore, or red and swollen (inflamed). Laser surgery may also be recommended if the skin over your varicose veins is irritated.. Varicose veins are not usually a serious health problem, but they can be painful. You may also not like how they look.. All surgeries have some risks. Some possible risks of laser varicose vein surgery include: ...
Historical Background By the 1890s Trendelenburg not only had developed the compression test to evaluate saphenous vein reflux but also had performed great saphenous vein ligations using a transverse upper thigh incision, thus establishing the foundation for surgical treatment of varicose veins. In 1916 Homans described ligation of the saphenofemoral junction as it is commonly…
Despite the apparent superiority of arterial conduits for coronary artery bypass grafting (CABG), the long saphenous vein remains the most commonly used graft. The high failure rate of long saphenous vein grafts (SVGs) over time is therefore an important limiting factor for the long-term outcomes of CABG. Various methods to improve SVG patency have been proposed, although few have had a significant impact on clinical practice. External SVG supports have been a focus of research over the past 50 years, with their use intended to minimize well-documented pathophysiological changes that occur in the SVG following implantation into the coronary circulation. These devices have been trialled extensively in animal models to assess their impact on both the morphology and the function of vascular conduits. Recently, a number of studies have been conducted in patients, leading to a substantial development in their design and the accumulation of a large body of evidence attesting to their potential benefit in CABG
Szabo and colleagues evaluated the effectiveness of EVRF treatment and analysed the three-year results of using the device for endovenous radiofrequency ablation and spider vein treatments from July 2011 to March 2015 to treat 751 saphenous reflux and varicosity patients.. Radiofrequency ablation using the EVRF CR45i catheter was performed on 751 limbs (628 greater saphenous vein, 102 small saphenous vein and 21 for both). Complete occlusion was found in 743 of 751 cases (99%) at one month. At one-year follow-up, 15 of 530 patients showed recanalisation longer than 5cm (97.2% one-year occlusion) without clinical symptoms. The three-year occlusion rate was 96.6% (two of 59 patients had an open vein segment). At one-year follow-up the investigators evaluated the postoperative pain reported by the patients on a visual analogue scale (2.4 preoperatively, 1.2, 0.4 and 0.1 at one week, one month and one year postoperatively, respectively) and Venous Clinical Severity Scores (7.7, 3.9 and 1.8 before ...
The use of embolic protection devices (EPDs) when treating coronary saphenous vein bypass grafts, performing carotid arterial stenting and treating acute coronary syndromes is well accepted.
The saphenous vein is the longest in the body extending from the top of the foot to the upper groin area. Problems associated with saphenous veins include throm
TY - JOUR. T1 - Ischemia-induced interleukin-8 release after human heart transplantation. T2 - A potential role for endothelial cells. AU - Oz, M. C.. AU - Liao, H.. AU - Naka, Y.. AU - Seldomridge, A.. AU - Becker, D. N.. AU - Michler, R. E.. AU - Smith, C. R.. AU - Rose, E. A.. AU - Stern, D. M.. AU - Pinsky, D. J.. PY - 1995. Y1 - 1995. N2 - Background: Interleukin-8 (IL-8) secreted from endothelial cells is a powerful neutrophil chemoattractant and activator. We hypothesized that human endothelial cells deprived of oxygen would secrete IL-8, which might translate into elevated IL-8 production after cardiac ischemia. Furthermore, we hypothesized that coronary sinus (CS) IL-8 levels would be particularly high after cardiac preservation for transplantation, due to extended ischemic times. Methods and Results: Human saphenous vein endothelial cells exposed to a hypoxic environment (PO2 ,20 mm Hg) demonstrated a time-dependent release of IL-8 (measured by ELISA) into the culture supernatant as ...
A high intake of the omega-3 fatty acid docosahexaenoate [docosahexaenoic acid (DHA)] has been associated with systemic antiinflammatory effects and cardiovascular protection. Cyclooxygenase (COX)-2 is responsible for the overproduction of prostaglandins (PG) at inflammatory sites, and its expression is increased in atheroma. We studied the effects of DHA on COX-2 expression and activity in human saphenous vein endothelial cells challenged with proinflammatory stimuli. A ≥24-h exposure to DHA reduced COX-2 expression and activity induced by IL-1, without affecting COX-1 expression. DHA effect depended on the NF-κB-binding site in the COX-2 promoter. EMSAs confirmed that DHA attenuated NF-κB activation. Because MAPK, PKC, and NAD(P)H oxidase all participate in IL-1-mediated COX-2 expression, we also tested whether these enzymes were involved in DHA effects. Western blots showed that DHA blocked nuclear p65 NF-κB subunit translocation by decreasing cytokine-stimulated reactive oxygen species ...
Lourdes Alanis, MD, MPH, a third-year medical resident at Cooper University Health Care, won the SIR Case Competition during the Society of Interventional Radiology (SIR) 2017 Conference held in Washington, D.C., in March.. Dr. Alanis case presentation, titled Aortocoronary Saphenous Vein Graft Pseudoaneurysm Presenting as an Anterior Mediastinal Mass, was selected as the winner among the 70 cases submitted nationally. Read more.. ...
Lassociation International Union of Endovascular(IUE) a pour objet la formation médicale continue et la recherche, de fédérer son action au plan national et international, de former et détablir des programmes daides et dinterventions dans des pays défavorisés ou en besoin dassistance médicale.
Welcome to the Pathology Education Informational Resource (PEIR) Digital Library, a multidisciplinary public access image database for use in medical education. ...
Varicose veins are a common cosmetic concern that most frequently affect the legs. In some cases, varicose veins also cause discomfort or pain. If you suffer from varicose veins, there are a variety of non-invasive vein therapy options available to eliminate them and restore your confidence in the appearance of your legs.. Causes of Varicose Veins. Varicose veins occur when the one-way valves inside the veins malfunction or wear out. When these valves do not function properly, blood pools inside the vein rather than being transported up the legs to the heart. Pooling blood causes the vein to expand and turn dark red, blue, or purple, forming a varicose vein. In many cases, the valves simply wear out due to age. However, there are other factors that contribute to the formation of varicose veins. Being overweight and minimally-active puts excess strain on your cardiovascular system, affecting the veins and their valves. Pregnancy can also cause the formation of varicose veins. Varicose veins are ...
BioAssay record AID 212805 submitted by ChEMBL: In vitro Thromboxane receptor antagonist against U-46619 induced contraction of dog saphenous vein.
Comparison of Conventional and No-Touch Techniques in Harvesting Saphenous Vein for Coronary Artery Bypass Grafting in View of Endothelial Damage ...
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The small saphenous vein (also short saphenous vein or lesser saphenous vein) is a relatively large superficial vein of the ... Vein stripping is an effective treatment. The small saphenous vein may be harvested for transplant to elsewhere in the body, ... The origin of the small saphenous vein, (SSV) is where the dorsal vein from the fifth digit (smallest toe) merges with the ... it can merge with the Giacomini vein and drain in the GSV at the superior 1/3 of the thigh. The small saphenous vein may become ...
The great saphenous vein (GSV, alternately "long saphenous vein"; /səˈfiːnəs/) is a large, subcutaneous, superficial vein of ... Great saphenous vein. Deep dissection. Anterior view. Illustration depicting veins of the leg including great saphenous vein ( ... Varicose veins: The great saphenous vein, like other superficial veins, can become varicose; swollen, twisted and lengthened, ... the great saphenous vein dives down deep through the cribriform fascia of the saphenous opening to join the femoral vein. It ...
Varicose Anterior accessory saphenous vein Varicose Anterior accessory saphenous vein at the knee Superficial veins oflower ... The anterior accessory saphenous vein is a special anterior tributary of the great saphenous vein (GSV), draining the antero- ... Usually it joins GSV very near the saphenous-femoral junction at the saphenous arch or can drain directly in the femoral vein. ... The vein can be identified near the saphenous ostium by a typical ultrasonographic image the so-called Mickey mouse sign (the 2 ...
Venous cutdown procedures most commonly target the great saphenous vein in the leg because it is superficial, easily accessible ... In neonates, scalp veins can also be used if other peripheral veins are not accessible. Umbilical veins are also an option in ... Lee MM, Loyd JW (2019). Saphenous Vein Cutdown. StatPearls. StatPearls Publishing. PMID 30422475. Retrieved 2019-10-31. Haas NA ... When accessing veins in children, certain other factors are considered such as their smaller caliber veins and anatomical ...
The small saphenous vein. Popliteal vein is labeled at top. The popliteal vein. Drake, Richard L. (Richard Lee), 1950- (2005). ... The popliteal vein is a vein of the lower limb. It is formed from the anterior tibial vein and the posterior tibial vein. It ... the fibular veins. The popliteal vein may be doubled in up to 35% of people. The popliteal vein drains blood from the leg. The ... The popliteal vein is formed by the junction of the venae comitantes of the anterior tibial vein and the posterior tibial vein ...
... popliteal vein popliteal artery, a continuation of the femoral artery small saphenous vein (termination) Popliteal lymph nodes ... Small saphenous vein and its tributaries. The popliteal, posterior tibial, and peroneal arteries. Nerves of the right lower ... This contains the small saphenous vein, the terminal branch of the posterior cutaneous nerve of the thigh, posterior division ...
With this method, the long saphenous vein is preserved. Cryosurgery- A cryoprobe is passed down the long saphenous vein ... Myers wrote that open surgery for small saphenous vein reflux is obsolete. Myers said these veins should be treated with ... Hammarsten J, Pedersen P, Cederlund CG, Campanello M (August 1990). "Long saphenous vein saving surgery for varicose veins. A ... Varicose veins in the legs could be due to ovarian vein reflux. Both ovarian and internal iliac vein reflux causes leg varicose ...
The great saphenous vein and its tributaries at the fossa ovalis. The great saphenous vein and its tributaries. The femoral ... vein and its tributaries. Superficial circumflex iliac artery (NOTE: this diagram is mislabelled. The "superficial circumflex ...
The great saphenous vein and its tributaries. The femoral vein and its tributaries. Superficial veins oflower limbSuperficial ... The superficial epigastric vein is a vein which travels with the superficial epigastric artery. It joins the accessory ... saphenous vein near the fossa ovalis. The subcutaneous inguinal ring. ... Veins of the lower limb, All stub articles, Cardiovascular system stubs). ...
This procedure can result in damage to the saphenous nerve due to its intimate path with the great saphenous vein, resulting in ... The saphenous vein is most commonly used. This procedure has fallen out of favor with the development of safer techniques for ... The greater saphenous vein is identified on the surface above the medial malleolus, a full-thickness transverse skin incision ... Venous cutdown is an emergency procedure in which the vein is exposed surgically and then a cannula is inserted into the vein ...
Zamboni, Paolo; Mendoza, Erika; Gianesini, Sergio (2018-05-29). Saphenous vein-sparing strategies in chronic venous disease. ... Saphenous Vein-Sparing Strategies in Chronic Venous Disease. Springer. ISBN 978-3-319-70638-2.{{cite book}}: CS1 maint: ... testing a minimally invasive and conservative treatment of the saphenous vein: the CHIVA method. On this topic he conducted ... and or compression of the Internal jugular vein, azygos vein. CCSVI was initially brought forth as possible contributing factor ...
Harskamp, RE; Lopes, RD; Baisden, CE; de Winter, RJ; Alexander, JH (May 2013). "Saphenous vein graft failure after coronary ... Motwani, JG; Topol, EJ (10 March 1998). "Aortocoronary saphenous vein graft disease: pathogenesis, predisposition, and ... The rational was that it will protect the vein from intimal damage and thrombosis by aiding with the adaptation of the vein ... The external scaffold provides a mechanical support for the vein graft, absorbs the high arterial pressure, constrict the vein ...
The lateral marginal vein is a continuation of the dorsal venous arch of the foot. It is the origin of the short saphenous vein ... Medial marginal vein Blanchemaison, Philippe; Camponovo, Jérôme; Greney, Philippe (2008). "SERVIER - Veins of the foot - ... Marginal veins and their branches". Servier (phlebologia.com). LES LABORATOIRES SERVIER. Archived from the original on 2008-08- ... Varicose Veins", Vascular Medicine: A Companion to Braunwald's Heart Disease (Second Edition), Philadelphia: W.B. Saunders, pp ...
... saphenous vein) صافن sāfin, saphenous vein (saphena vein). The saphena vein is in the human leg. It was one of the veins used ... Albucasis's description of how to take blood from the saphenous vein is in Arabic together with English translation in the book ... In addition to medical books, some medieval Arabic general-purpose dictionaries have al-sāfin = "saphenous vein". One of these ... "saphenous vein" in Haly Abbas, Albucasis and Avicenna, and on page 45 has Al-Razi's usage. ...
Donaldson MC, Mannick JA, Whittemore AD., "Femoral-distal bypass with in situ greater saphenous vein. Long-term results using ... where the saphenous vein is disconnected from the venous system and connected to arteries above and below the occluded segment ... Since the leg veins usually contain a number of valves that direct flow towards the heart, they cannot directly be used as ... The blade is designed to prevent exposure of the vein intima to the sharp cutting surface to avoid damage to the vessel wall. ...
Raja SG, Haider Z, Ahmad M, Zaman H (2004). "Saphenous vein grafts: to use or not to use?". Heart Lung Circ. 13 (4): 403-9. doi ... however internal mammary artery grafts have demonstrated significantly better long-term patency rates than great saphenous vein ... Coronary artery bypass surgery involves an artery or vein from the patient being implanted to bypass narrowings or occlusions ... Several arteries and veins can be used, ...
Moreover, the particular vein, great saphenous vein was shown to be more durable over the years after surgery. Also, when ... Connolly, John E. (January 2011). "The history of the in situ saphenous vein bypass". Journal of Vascular Surgery. 53 (1): 241- ... The use of either a man-made graft or a vein from the leg is determined by the surgeon. Both ends of the chosen graft are sewn ... Usually, a healthy vein is located and sewn above and below the blockage to bypass the narrowed or blocked femoral artery. This ...
Saphenous Vein Sparing Superficial Inguinal Dissection in Lower Extremity Melanoma. Öztürk MB, Akan A, Özkaya Ö, Egemen O, ...
Veins, mainly the great saphenous vein (GSV) are the most frequently used conduits in bypass surgeries (CABG or PABG), due to ... The patency rates of saphenous vein grafts after CABG at 1 year is approximately 80%. After 5 years the patency rate drops to ... Having an intact outer fat pedicle is what differentiates the two main techniques for harvesting saphenous vein grafts. ... McKavanagh P, Yanagawa B, Zawadowski G, Cheema A (December 2017). "Management and Prevention of Saphenous Vein Graft Failure: A ...
The great saphenous vein and its tributaries at the fossa ovalis. Superficial veins of lower limb Superficial dissection. ... which pierces fascia lata lateral to the saphenous opening), and lymphatics. It transmits the great saphenous vein and other ... In anatomy, the saphenous opening (saphenous hiatus, also fossa ovalis) is an oval opening in the upper mid part of the fascia ... by a thin perforated part of the superficial fascia called the fascia cribrosa which is pierced by the great saphenous vein, ...
Radial-artery or saphenous-vein grafts in coronary-artery bypass surgery. New England Journal of Medicine, 378(22), 2069-2077; ... "Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery". New England Journal of Medicine. 378 (22): 2069-2077 ... He is credited with performing the first totally thoracoscopic bilateral pulmonary vein isolation procedure. He is the co- ...
... accompanying the long saphenous vein. One of these filaments passes through the saphenous opening; a second becomes ... The great saphenous vein and its tributaries at the fossa ovalis. Cross section of thigh This article incorporates text in the ... communicates with the saphenous nerve, and gives off several cutaneous branches. It then passes down to supply the integument ... the anterior division of medial cutaneous nerve and the infrapatellar branch of the saphenous, to form the patellar plexus. In ...
The conduit vessel that is often used is the Saphenous vein. This vein is harvested using a technique known as endoscopic ...
Schlüter M, Chevalier B, Seth A, Bach R, Farah B, Hauptmann KE, Grube E, Schofer J (March 2003). "Saphenous vein graft stenting ... Schlüter M, Chevalier B, Seth A, Bach R, Farah B, Hauptmann KE, Grube E, Schofer J (March 2003). "Saphenous vein graft stenting ...
... and below with the sartorius and internal saphenous nerve; the internal saphenous vein crosses it lying superficially to the ...
Béclard's hernia: A femoral hernia through the opening of the saphenous vein. Béclard's triangle: An area whose boundaries are ...
The internal mammary artery or saphenous vein can be used as grafts. The grafts are used to provide an alternate path for blood ... Varicose veins - Veins that have become enlarged and tortuous with failed valves, commonly in the legs. Vericose veins have ... Deep vein thrombosis (DVT) and pulmonary embolism (PE) - Formation of a thrombus in a deep vein, commonly in the legs that may ... Surgery and sclerotherapy are two options for treating varicose veins. Vasculitis - Inflammation of blood vessels (veins & ...
"Mechanisms of action of eperisone on isolated dog saphenous arteries and veins". Jpn. J. Pharmacol. 50 (3): 271-82. doi:10.1254 ...
Araújo D, Caramona MM, Osswald W (June 1983). "On the mechanism of action of amezinium methylsulphate on the dog saphenous vein ...
"Elevated Sex Steroid Hormones in Great Saphenous Veins in Men". Journal of Vascular Surgery. 51 (3): 639-646. doi:10.1016/j.jvs ... "All in Vein: Vascularity in Bodybuilding is Controversial". Retrieved September 21, 2012. Sisco, Peter (1999). Ironman's ... and often extensively-ramified superficial veins. The skin appears "thin"-sometimes virtually transparent-due to an extreme ...
... the saphenous veins are saved, a considerable advantage since these veins are the best material for by-passing the peripheral ... of the saphenous vein. The CHIVA technique as a treatment of venous insufficiency is now accepted as the standard of care in ... resulting in ulcer healing and returning the normal caliber of the veins, including varicose veins. It merely consists in the ... A prospective study of a vein sparing technique for the management of varicose vein disease The American Journal of Surgery - ...
... great saphenous vein ligation as a treatment of varicose veins. This disambiguation page lists articles associated with the ...
The major structure that passes anterior to the medial malleolus is the saphenous vein. Structures that pass behind medial ... Tibialis posterior tendon Flexor digitorum longus Posterior tibial artery Posterior tibial vein Tibial nerve Flexor hallucis ...
Complications can be the development of lymphedema though not removing the saphenous vein during the surgery will help prevent ...
... which separates it from the femoral artery and vein and internal saphenous vein, and lower down with the profunda femoris ... the obturator artery and vein being interposed. By its external border with the psoas major, the femoral artery resting upon ...
They lie medial to the femoral vein under the cribriform fascia. The uppermost node is in the groin, under the inguinal ... They are divided into three groups: inferior - inferior of the saphenous opening of the leg, receive drainage from lower legs ... A view of the different inguinal lymph nodes Murine inguinal lymph node beneath the bifurcation of superior epigastric vein. ... superomedial - located at the middle of the saphenous opening, take drainage from the perineum and genitals. There are ...
It receives drainage from great saphenous vein, circumflex veins, and veins corresponding to the branches of the femoral artery ... and upper part of the great saphenous vein. The deep fascia has a saphenous opening and the opening is covered by the cribiform ... Femoral vein and its tributaries - The vein lies medial to the femoral artery at the base of the triangle but as it approaches ... medial to it lies the femoral vein. Thus the femoral vein, once located, allows for femoral venipuncture.[citation needed]. ...
... basilic vein - usually the largest vein in the arm: often used for dialysis access small saphenous vein great saphenous vein - ... external jugular vein cephalic vein - glides along the biceps: the "signature vein" of bodybuilders median cubital vein - often ... for coronary artery bypass surgery Deep veins Varicose veins Vascularity "All About Varicose Veins , What Causes Varicose Veins ... A superficial vein is a vein that is close to the surface of the body. This differs from deep veins that are far from the ...
A tap is made on the lower part of the leg on the long saphenous varicose vein with one hand. If an impulse can be felt at the ... The impulse is felt at the saphenous opening because of the incompetence of the valves in the superficial venous system. Babu, ... Schwartz's test is a clinical test used for confirming the diagnosis of long standing varicose veins. The clinician exposes the ... Butie, A. (1995). Clinical Examination of Varicose Veins. Dermatologic Surgery, 21(1), 52-56. (Medical signs). ...
May - Dr René Favaloro performs the first saphenous vein autograft in coronary artery bypass surgery, at the Cleveland Clinic ... surgical treatment by the saphenous vein graft technique". American Journal of Cardiology. 28 (5): 598-607. doi:10.1016/0002- ...
Damage to the saphenous nerve and its infrapatellar branch is possible during medial knee surgery, potentially causing numbness ... As with all surgeries, there is a risk of bleeding, wound problems, deep vein thrombosis, and infection that can complicate the ... Widjicks CA, Westerhaus BD, Brand EJ, Johansen S, Engebretsen L, LaPrade RF (2010). "Sartorial branch of the saphenous nerve in ...
It is perforated by the great saphenous vein and by numerous blood and lymphatic vessels. (A structure in anatomy that is ... in preventing new vascularization when surgery is performed at the join between the great saphenous vein and the femoral vein. ... The cribriform fascia, fascia cribrosa also Hesselbach's fascia is the portion of fascia covering the saphenous opening in the ...
The pathogenesis of saphenous vein graft stenosis with emphasis on structural and functional differences between veins and ... This is well known to thoracic surgeons: a vein removed to bypass a coronary artery and grafted into the artery position ...
"Endoscopic versus open saphenous vein harvest for femoral to below the knee arterial bypass using saphenous vein graft". J Vasc ... Crouch JD (1999). "Open versus endoscopic saphenous vein harvesting: wound complications and vein quality". Annals of Thoracic ... Historically, vessels-such as the great saphenous vein in the leg or the radial artery in the arm-were obtained using a ... Meyer DM (2000). "Histologic evidence of the safety of endoscopic saphenous vein graft preparation". Ann Thorac Surg. 70 (2): ...
... a tributary of the great saphenous vein. In contrast to the deep dorsal vein, it lies outside Buck's fascia. It is possible for ... The deep vein also communicates below the pubic symphysis with the internal pudendal vein. The dorsal veins of the penis can be ... In human anatomy, the dorsal veins of the penis comprise the superficial dorsal vein of the penis and the deep dorsal vein of ... Due to the volume of response, Snickers clarified in its own viral tweet that the "veins remain". The veins of the right half ...
Other commonly employed conduits are the right internal mammary artery (RITA), the radial artery or great saphenous vein (SVG ...
... vertebrae sacral promontory sacroiliac joint sacrum sagittal crest sagittal suture saliva salivary gland salpinx saphenous vein ... internal carotid artery internal cerebral vein internal ear internal iliac artery internal iliac vein internal jugular vein ... trigone colliculus collum colon columns of the fornix commissure common carotid artery common facial vein communicating veins ... pons pontine nuclei pontocerebellum popliteal artery popliteal bursa popliteal fossa popliteal vein popliteus portal vein ...
To strip or not to strip the long saphenous vein: a varicose veins trial. Br J Surg 1981;68:426-8. Nicolaides, AN; Zukowski, A ... Surgery for primary troncular varicose veins without stripping the saphenous vein: pre- and post-operative evaluationby duplex ... Long saphenous vein saving surgery for varicose veins: a long-term follow-up. Eur J Vasc Surg 1990;4:361-64. Hoare, M.C; Royle ... Deep vein thrombosis: US assessment using vein compression. Radiology 1987;162:191. Cohan, RH; Leder, RA et al. Extravascular ...
... also have been shown to be superior to bare-metal stents in reducing short-term complications of stenting in saphenous vein ...
It has become an accepted alternative conduit, and is particularly useful in patients who do not have suitable saphenous veins ...
The great saphenous vein (GSV), and the small saphenous vein (SSV) are superficial veins which drain into respectively, the ... These veins are deep veins. Perforator veins drain superficial veins into the deep veins. Three anatomic compartments are ... The veins most often found to be incompetent are the saphenous veins and the perforators communicating with the deep veins of ... The GSV can be located in the saphenous compartment where together with the Giacomini vein and the accessory saphenous vein ( ...
Renocaval bypass with saphenous vein: a segment of the great saphenous vein is used as a second connection between the LRV and ... the renal vein). Furthermore, the venous return from the left gonadal vein returning to the left renal vein is blocked, thus ... Gonadal vein transposition: The gonadal veins are connected to the (IVC) to reduce the amount of blood backed up in the pelvis ... Occasionally, the gonadal vein swelling may lead to ovarian vein syndrome in women. Nausea and vomiting can result due to ...
... and perforated by the small saphenous vein. It receives an expansion from the tendon of the biceps femoris laterally, and from ...
Learn more about angiographic outcomes of veins vs arteries in CABG. ... Background: Currently, saphenous vein (SV) and radial artery (RA) are the most commonly used conduits in combination with the ... Currently, the saphenous vein (SV) and radial artery (RA) are the most commonly used conduits after LIMA for CABG. Although the ... A Meta-analysis of Randomized Controlled Trials on Mid-term Angiographic Outcomes for Radial Artery versus Saphenous Vein in ...
It can be the cause of varicose veins. ... The small saphenous vein is a superficial blood vessel in the ... It starts from two veins in the foot and runs up the leg. Aside from the large saphenous vein, the small saphenous vein is one ... The small saphenous vein is a large superficial vein that is connected to the larger saphenous vein. ... A common condition associated with the small saphenous vein is varicose veins. When the valves in the saphenous vein become ...
Endovenous laser ablation of great saphenous vein and perforator veins improves venous stasis ulcer healing. Download Prime ... Endovenous Laser Ablation of Great Saphenous Vein and Perforator Veins Improves Venous Stasis Ulcer Healing. Ann Vasc Surg. ... Endovenous laser ablation of great saphenous vein and perforator veins improves venous stasis ulcer healing. Ann Vasc Surg. ... Endovenous laser ablation of great saphenous vein and perforator veins improves venous stasis ulcer healing.. Ann Vasc Surg. ...
... for the treatment of incompetent varicose great saphenous veins (GSVs). The present report describes long-term follow-up at 5 ... Results: A total of 225 patients had 295 GSVs treated by RFA, achieving an initial vein occlusion rate of 100 per cent. With 80 ... European multicentre cohort study on radiofrequency segmental thermal ablation for incompetent great saphenous veins Br J Surg ...
Welcome to the Pathology Education Informational Resource (PEIR) Digital Library, a multidisciplinary public access image database for use in medical education. ...
Contractile and morphologic properties of a saphenous vein after 12 years as an aortocoronary bypass graft. *Mark ... Contractile and morphologic properties of a saphenous vein after 12 years as an aortocoronary bypass graft}}, volume = {{28}}, ...
Home Cardiology The risk factors for radial artery and saphenous vein graft occlusion are... ... Objectives. To determine risk factors for radial artery and saphenous vein graft occlusion during long-term follow-up after ... The sole independent risk factor identified for saphenous vein graft occlusion was tobacco smoking 8-12 years postoperatively. ... The risk factors for radial artery and saphenous vein graft occlusion are different. By ...
The Dutch experience in percutaneous transluminal angioplasty of narrowed saphenous veins used for aortocoronary arterial ... the long-term follow-up of 454 patients who underwent angioplasty of greater than or equal to 1 saphenous vein bypass graft was ... The Dutch experience in percutaneous transluminal angioplasty of narrowed saphenous veins used for aortocoronary arterial ...
Prejunctional effects of naftidrofuryl in canine saphenous veins. / Aarhus, L. L.; Thome, S.; Zander, J. et al. ... Aarhus, LL, Thome, S, Zander, J & Vanhoutte, PM 1985, Prejunctional effects of naftidrofuryl in canine saphenous veins, ... Prejunctional effects of naftidrofuryl in canine saphenous veins. In: Federation Proceedings. 1985 ; Vol. 44, No. 4. pp. No. ... title = "Prejunctional effects of naftidrofuryl in canine saphenous veins",. author = "Aarhus, {L. L.} and S. Thome and J. ...
... augments neo-vasa vasorum formation and reduces oxidative stress in saphenous vein grafts from pigs used as a model of diabetes ...
Saphenous vein. The great (long) saphenous vein (GSV) is located 2 cm anterior to the medial malleolus, traverses the tibia, ... the saphenous veins have an 80-90% early patency rate, which decreases to 50% at 10 years. The saphenous vein is generally ... and saphenous branch of the genicular artery. The small (short) saphenous vein (SSV) is located 1 cm posterior to the lateral ... In rare circumstances (eg, CABG performed for acute anterior myocardial infarction), a saphenous vein graft may be placed to ...
... but may also refer to the small saphenous vein ... noun Usually referring to the great saphenous vein, ... Saphenous vein - The saphenous veins there are two, the great and the small saphenous veins - serve as the principal veins ... Saphenous vein - may refer to: *Great saphenous vein *Small saphenous vein … Wikipedia ... Saphenous vein, great - The larger of the two saphenous veins, the principal veins that run up the leg superficially (near the ...
The great saphenous vein (also called the large saphenous vein) goes from the foot all… ... the great and the small saphenous veins - serve as the principal veins running superficially (near the surface) up the leg. ... Saphenous vein, great. Look at other dictionaries:. *. Saphenous vein - may refer to: *Great saphenous vein *Small saphenous ... Saphenous vein. The saphenous veins - there are two, the great and the small saphenous veins - serve as the principal veins ...
Percutaneous intervention in saphenous vein bypass graft disease: case against the use of drug-eluting stents. J Am Coll ... Percutaneous intervention in saphenous vein bypass graft disease: case against the use of drug-eluting stents.. ...
Optimal saphenous vein harvesting positioning for coronary bypass surgery is achieved with the Saphenous Vein Harvest Pad from ... The Saphenous Vein Harvest Pad holds patients legs and supports the upper thigh at the optimal position for assessment and ... harvest of the saphenous vein during coronary bypass surgery.. *Holds legs externally-rotated and slightly-flexed for minimally ...
Republished: Thrombectomy for late occlusion of high flow extracranial-intracranial saphenous vein bypass graft after 27 years ... Republished: Thrombectomy for late occlusion of high flow extracranial-intracranial saphenous vein bypass graft after 27 years ...
Tumorcells were seen in the dermis, and the lumen, as well asoutside the wall of saphenous vein, but not in the epidermis.Only ... Intravascular and Extravascular Migratory, Metastatic Melanoma of the Great Saphenous Vein. Authors: Sayed, Mahmood Ali. Joshi ... All swellings, along with, part of saphenous vein tillthe knee, and small part of skin were excised under GA.Microscopically, ... Wereport this very rare case of metastatic melanoma along thewall of great saphenous vein (GSV), showing intra and ...
Saphenous Vein Mapping online and avail upto 40% discount with the top Labs in Pakistan through Healthwire anywhere, anytime. ...
... with varices involving the short saphenous vein system and some of the frequently observed ... Note that a portion of the short saphenous vein (1) is shown. The veins (2), (3) and (4) are tributaries of the long saphenous ... Varicose veins The Short Saphenous System , Varicose veins. Posted on Apr 12, 2014 in Varicose veins of the lower extremity , 0 ... The Long Saphenous System (Varicose veins) Phlebectomy and interruption of incompetent lateral leg and foot communicating veins ...
Preoperative Evaluation of Saphenous Vein Graft Using Plain Computed Tomography for Endoscopic Saphenous Vein Harvesting]. ... We report the preoperative evaluation of saphenous vein (SV) graft using plain computed tomography (CT) for endoscopic ... Preoperative Evaluation of Saphenous Vein Graft Using Plain Computed Tomography for Endos ... saphenous vein harvesting (EVH). We made three-dimensional (3D) images of SV by using plain CT images. EVH was performed in 33 ...
Early and late outcome after carotid artery bypass grafting with saphenous vein. C Lauder, A Kelly, M M Thompson, N J M London ... CONCLUSIONS: In common with venous conduits elsewhere, carotid artery bypass grafting with saphenous vein is associated with a ... Prospective randomized trial of carotid endarterectomy with primary closure and patch angioplasty with saphenous vein, jugular ... This study was undertaken to determine outcome and durability of internal carotid artery bypass grafting with saphenous vein. ...
Pedicled no-touch saphenous vein graft harvest limits vascular smooth muscle cell activation: the PATENT saphenous vein graft ... 1 - Comparison of saphenous veins harvested for coronary artery bypass grafting. Examples of saphenous vein explants at ... 1 - Comparison of saphenous veins harvested for coronary artery bypass grafting. Examples of saphenous vein explants at ... Study comparing vein integrity and clinical outcomes in open vein harvesting and 2 types of endoscopic vein harvesting for ...
Risk of deep vein thrombosis in patients with cellulitis and erysipelas: a systematic review and meta-analysis. Thromb Res. ... Saphenous vein grafting in lower extremities. * Status postradical mastectomy. * Immunocompromise: Including patients who are ...
Small Saphenous Vein. The second most common vein to be treated for symptoms of vein disease, the small saphenous vein is a ... Great Saphenous Vein. The most commonly treated vein for symptoms of veinous disease, the Great saphenous vein is a long, ... The backward flow of blood in the veins is called reflux. Dilation of the vein wall prevents the vein valves from sealing ... Vein Function & Anatomy. home / patients & visitors / wellness tips & information / everyday health / vein health & issues / ...
Sympathetic blockage and reversed saphenous vein by-pass grafting: An experimental study. Authors: D. Bouchier-Hayes, W. A. L. ...
Lateral saphenous vein (Mouse, Rat): The animal is restrained by placing it head-first into a conical tube, decapicone, or ... The hind limb is extended over the top edge of the tube, applying pressure above the knee and making the lateral saphenous vein ... Warming the tail with a heat lamp or warm water bath enlarges the vein and facilitates sampling. The lateral tail vein is more ... Submandibular vein (Mouse): The mouse is restrained by gripping the skin over the back of the neck to pull the facial skin ...
The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein ... into membrane phospholipids of human saphenous vein endothelial cells were investigated. The CLA mixture and the individual ... The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein ...
  • For example, a rare variation involves the termination of the small saphenous vein into the femoral vein . (verywellhealth.com)
  • The great (long) saphenous vein (GSV) is located 2 cm anterior to the medial malleolus, traverses the tibia, and ascends posteriorly up the tibial border before emptying into the femoral vein. (medscape.com)
  • The long saphenous vein - the longest vein in the body - runs from the foot, up the medial side of the leg, to the groin, where it joins the femoral vein. (en-academic.com)
  • Deeper glands also are met with deep to the fascia cribrosa, close to the medial side of the femoral vein, and there is generally one in the femoral canal. (co.ma)
  • The veins (2), (3) and (4) are tributaries of the long saphenous vein and frequently can be removed by stripping. (imsurgeon.com)
  • Or, they may do the bypass using the long saphenous vein from the leg. (bidmc.org)
  • [ 5 ] The use of SV was pioneered by Favaloro in the early years of CABG, but its early occlusion and long-term attrition rates have resulted in only half of all vein grafts being patent and without significant stenoses at 10-years. (medscape.com)
  • For the second group, two smaller saphenous vein grafts were placed in the two parallel incisions. (wjps.ir)
  • Ticlopidine reduced the incidence of late occlusion of below-the-knee saphenous vein grafts. (ox.ac.uk)
  • If this helps, the approach is not separately billable and includes obtaining saphenous vein grafts. (aapc.com)
  • A total of 225 patients had 295 GSVs treated by RFA, achieving an initial vein occlusion rate of 100 per cent. (nih.gov)
  • Home Cardiology The risk factors for radial artery and saphenous vein graft occlusion are. (docwirenews.com)
  • To determine risk factors for radial artery and saphenous vein graft occlusion during long-term follow-up after coronary artery bypass grafting (CABG). (docwirenews.com)
  • The sole independent risk factor identified for saphenous vein graft occlusion was tobacco smoking 8-12 years postoperatively. (docwirenews.com)
  • OBJECTIVES: Early saphenous vein graft (SVG) occlusion is typically attributed to technical factors. (ox.ac.uk)
  • The small saphenous vein travels from the foot, over the outer portion of the ankle, up through the calf, and eventually merges with another vein near the knee called the popliteal vein. (verywellhealth.com)
  • In some people, the vein also drains elsewhere than the popliteal vein. (verywellhealth.com)
  • Blood from the small saphenous vein typically drains into the popliteal vein located around the knee. (verywellhealth.com)
  • The small (short) saphenous vein (SSV) is located 1 cm posterior to the lateral malleolus, runs centrally up the posterior calf, and drains into the popliteal vein. (medscape.com)
  • The small saphenous vein runs behind the outer malleolus (the protuberance on the outside of the ankle joint), comes up the back of the leg and joins the popliteal vein in the space behind the knee (the popliteal space). (en-academic.com)
  • The short saphenous vein runs up the back of the calf to join the popliteal vein at the back of the knee. (en-academic.com)
  • The short saphenous vein (1) is seen from its origin dis-tal to the external malleolus and extending proximally behind it, then a little lateral to the midline to terminate in the popliteal vein in the popliteal space beneath the deep fascia. (imsurgeon.com)
  • 1 Uncommon venous cannulations, such as the catheterization of the great saphenous vein or the popliteal vein (non-central venous lines), have also gained frequency among critically ill patients with COVID-19. (medintensiva.org)
  • Preoperative Evaluation of Saphenous Vein Graft Using Plain Computed Tomography for Endoscopic Saphenous Vein Harvesting]. (bvsalud.org)
  • Although wound healing complication is reduced when using endoscopic vein harvesting, there may be a negative impact on graft performance. (rbccv.org.br)
  • This is due to vascular damage associated with application of forces to the vein that are usually avoided in open vein harvesting, including traction, adventitial stripping, and venous compression. (rbccv.org.br)
  • Recently, endoscopic methods of harvesting have been described where the saphenous vein is removed intact and with minimal vascular damage caused. (rbccv.org.br)
  • In addition, the media, intima, and endothelium are damaged during vein harvesting due to a combination of vascular trauma and high-pressure intraluminal distention [8,9] . (rbccv.org.br)
  • Over 20 years ago, in an attempt to reduce these complications, the technique of endoscopic vein harvesting (EVH) was introduced [12] where the SV is removed, generally via two small incisions of approximately 5 mm above the knee and a small space created for introduction of the endoscope. (rbccv.org.br)
  • Clearly, EVH requires forces to be applied to the vein that are usually avoided in OVH or no-touch (NT) vein harvesting, including traction, adventitial stripping, and venous compression, conditions that may cause considerable vessel damage [11] . (rbccv.org.br)
  • The median and interquartile range of the force and torque peaks were calculated for the artery and vein harvesting procedures. (spie.org)
  • Intraoperative Thrombophilia-Associated Thrombosis of Both Saphenous Veins during Harvesting for Coronary Artery Bypass Grafting. (cdc.gov)
  • Factors affecting saphenous vein graft patency: clinical and angiographic study in 1402 symptomatic patients operated on between 1977 and 1999. (austin.org.au)
  • As coronary artery bypass grafting (CABG) conduits, the saphenous veins have an 80-90% early patency rate, which decreases to 50% at 10 years. (medscape.com)
  • Consequently, vein graft patency and surgical site infection may be compromised. (rbccv.org.br)
  • Graft patency is markedly improved when the saphenous vein is harvested atraumatically with minimal damage and with surrounding cushion of perivascular fat intact. (rbccv.org.br)
  • There is evidence to suggest that improved patency of endoscopically harvested saphenous veins is associated with the surgeon's experience of the technique. (rbccv.org.br)
  • While the effect of these techniques on vein graft patency have yet to be reported, the ability to obtain a superior graft with reduced wound complications will be of great benefit to patients undergoing coronary revascularization procedures. (rbccv.org.br)
  • The purpose of this study was to find the preoperative and intraoperative factors that affect vein graft patency.A total of 3715 graft angiograms in 1607 patients were studied for recurrence of angina. (austin.org.au)
  • 001) significantly affected graft patency.Saphenous vein graft patency improved over the course of the study. (austin.org.au)
  • Currently, saphenous vein (SV) and radial artery (RA) are the most commonly used conduits in combination with the left internal mammary artery for conventional coronary artery bypass graft surgery (CABG). (medscape.com)
  • Currently, the saphenous vein (SV) and radial artery (RA) are the most commonly used conduits after LIMA for CABG. (medscape.com)
  • From a cohort of 119 patients who had received a radial artery graft, 76 - of whom 55 also had at least one saphenous vein graft - underwent a preplanned direct angiography and anthropometric, biochemical, and endothelial function assessment 7.6-12.1 (mean 8.9) years after CABG. (docwirenews.com)
  • Our data support the contention that the pathogenesis of radial artery graft failure is distinct from vein graft disease and is related to hypertension status and systemic inflammation. (docwirenews.com)
  • Although the saphenous vein (SV) is the most used conduit for cardiac revascularization in patients undergoing coronary artery bypass grafting (CABG), its performance is inferior to the performance of the internal thoracic artery (ITA) [1-4] and, according to some, of the radial artery [5-7] . (rbccv.org.br)
  • The forces and torques in two radial artery and two saphenous vein procedures in human cadavers were recorded. (spie.org)
  • RESULTS: The median and interquartile range for saphenous vein harvests was larger than radial artery harvests. (spie.org)
  • Of 19,994 percutaneous transluminal coronary angioplasty procedures performed in The Netherlands between April 1980 and January 1989, the long-term follow-up of 454 patients who underwent angioplasty of greater than or equal to 1 saphenous vein bypass graft was reviewed. (eur.nl)
  • Percutaneous intervention in saphenous vein bypass graft disease: case against the use of drug-eluting stents. (uams.edu)
  • Aside from the large saphenous vein, the small saphenous vein is one of the leg's major venous blood vessels. (verywellhealth.com)
  • The great saphenous vein (also called the large saphenous vein) goes from the foot all the way up to the saphenous opening, an oval aperture in the broad fascia of the thigh, a fibrous membrane through which the vein passes. (en-academic.com)
  • The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein endothelial cells. (brad.ac.uk)
  • The effects of a conjugated linoleic acid (CLA) mixture of single isomers (50:50, w/w, cis9,trans11:trans10,cis12) and the individual isomers on (a) the production of resting and calcium ionophore stimulated 14C-eicosanoids and (b) the incorporation of 14C-arachidonic acid (AA) into membrane phospholipids of human saphenous vein endothelial cells were investigated. (brad.ac.uk)
  • Identification of the alpha 1c-adrenoceptor in rabbit arteries and the human saphenous vein using the polymerase chain reaction. (wikipedia.org)
  • The small saphenous vein is a blood vessel in the lower leg. (verywellhealth.com)
  • The small saphenous vein is also known as the lesser saphenous vein. (verywellhealth.com)
  • The small saphenous vein is a large superficial vein that is connected to the larger saphenous vein. (verywellhealth.com)
  • In a tiny percentage of the population, people have more than one small saphenous vein. (verywellhealth.com)
  • The small saphenous vein's primary function is to receive deoxygenated blood from the lower legs and return it to the heart. (verywellhealth.com)
  • A common condition associated with the small saphenous vein is varicose veins . (verywellhealth.com)
  • Sometimes, surgeons transplant the small saphenous vein elsewhere in the body. (verywellhealth.com)
  • Blood clots can also form in the small saphenous vein. (verywellhealth.com)
  • If you have a superficial blood clot of the small saphenous vein, you may experience pain, redness, and swelling. (verywellhealth.com)
  • Usually referring to the great saphenous vein , but may also refer to the small saphenous vein . (en-academic.com)
  • Saphenous vein - The saphenous veins there are two, the great and the small saphenous veins - serve as the principal veins running superficially (near the surface) up the leg. (en-academic.com)
  • The second most common vein to be treated for symptoms of vein disease, the small saphenous vein is a superficial vein that runs from the outside of the foot up the back of the calf. (universityhealth.org)
  • The cranial extension of the small saphenous vein: Usual course of an unusual proximal thigh extension tributary of the small saphenous vein. (marmara.edu.tr)
  • This superficial vein connects the great and small saphenous vein. (innerbody.com)
  • Published experience comparing open vein harvest (OVH) with endoscopic vein harvest (EVH) suggests decreased wound-related complications, improved patient satisfaction, shorter hospital stay, and reduced postoperative pain at the harvest site following EVH. (medscape.com)
  • Prospective randomized trial of carotid endarterectomy with primary closure and patch angioplasty with saphenous vein, jugular vein, and polytetrafluoroethylene: long-term follow-up. (qxmd.com)
  • nose are situated between the base to the internal jugular vein from the spinal position. (wildwoodclinic.com)
  • Cats were anesthetized, and 3.0 mL blood was collected from the jugular vein or medial saphenous vein. (cdc.gov)
  • When a clot involves a vein, it's called superficial thrombophlebitis. (verywellhealth.com)
  • The most commonly treated vein for symptoms of veinous disease, the Great saphenous vein is a long, superficial vein that runs from the inside of the foot and ends near the groin where it connects with the deep vein system. (universityhealth.org)
  • One way valves allow only upward blood flow toward the heart and inward blood flow from the superficial to the deep veins. (universityhealth.org)
  • Varicose veins are superficial veins that have become enlarged and twisted. (mdwiki.org)
  • Blood clotting within affected veins, termed superficial thrombophlebitis . (mdwiki.org)
  • These are frequently isolated to the superficial veins, but can extend into deep veins, becoming a more serious problem. (mdwiki.org)
  • DOC Vein Management focuses are restoring mobility and quality of life to our patients by offering state-of-the-art vein procedures that focus on the Superficial Veins, often the underlying cause of painful varicose veins, and other serious Vein disease. (docveinmanagement.com)
  • How a varicose vein forms in a leg. (mdwiki.org)
  • Figure B shows a varicose vein with a deformed valve, abnormal blood flow, and thin, stretched walls. (mdwiki.org)
  • People who inject drugs into their veins have a higher risk of developing a severe infection due to a venous blood clot. (verywellhealth.com)
  • This study was undertaken to determine outcome and durability of internal carotid artery bypass grafting with saphenous vein. (qxmd.com)
  • Carotid endarterectomy outcome with vein or Dacron graft patch angioplasty and internal carotid artery shortening. (qxmd.com)
  • Choice of material for internal carotid artery bypass grafting: vein or prosthetic? (qxmd.com)
  • In common with venous conduits elsewhere, carotid artery bypass grafting with saphenous vein is associated with a high incidence of early graft stenosis. (qxmd.com)
  • In this case, they would connect the saphenous vein graft to the carotid artery in the neck, pass it under the skin, and sew it to the middle cerebral artery inside the head. (bidmc.org)
  • The patient was treated by trapping of the left ICA with external carotid artery-saphenous vein graft-M2 bypass without complications. (elsevier.com)
  • Restless legs syndrome appears to be a common overlapping clinical syndrome in people with varicose veins and other chronic venous insufficiency . (mdwiki.org)
  • We sought to compare the outcomes of endovenous laser ablation (EVLA) of the great saphenous vein (GSV) to EVLA of the GSV and calf incompetent perforator veins (IPVs) in management of venous stasis ulcers (VSUs). (unboundmedicine.com)
  • This was a prospective study of radiofrequency segmental thermal ablation (RFA) for the treatment of incompetent varicose great saphenous veins (GSVs). (nih.gov)
  • Saphenous vein, great - The larger of the two saphenous veins, the principal veins that run up the leg superficially (near the surface). (en-academic.com)
  • Wereport this very rare case of metastatic melanoma along thewall of great saphenous vein (GSV), showing intra and extravascular metastasis. (who.int)
  • The dorsal venous arch in the foot is located at the point where the first and fifth digit dorsal veins run into the small and great saphenous veins. (innerbody.com)
  • crossing over the distal border is the termination of the great saphenous vein. (co.ma)
  • The course of the great saphenous vein in the thigh is indicated by a line extending from the adductor tubercle of the medial epicondyle of the femur to the distal part of the fossa ovalis. (co.ma)
  • The vertical or femoral chain lies in close relation to the upper end of the great saphenous vein. (co.ma)
  • The freshwater stingray, due to its sharp characteristics, injured the great saphenous vein, requiring surgical intervention. (bvsalud.org)
  • Development of a risk score for early saphenous vein graft failure: An individual patient data meta-analysis. (ox.ac.uk)
  • Antoniades C., SAFINOUS-CABG (Saphenous Vein Graft Failure-An Outcomes Study in Coronary Artery Bypass Grafting) group None. (ox.ac.uk)
  • When the valves in the saphenous vein become faulty, venous insufficiency occurs. (verywellhealth.com)
  • When the calf muscle contracts, it squeezes vein valves open so blood can flow upwards. (universityhealth.org)
  • Dilation of the vein wall prevents the vein valves from sealing completely. (universityhealth.org)
  • [2] The underlying mechanism involves weak or damaged valves in the veins. (mdwiki.org)
  • For this process to occur, the veins contain one-way valves that open and close, helping blood flow against gravity towards the heart. (docveinmanagement.com)
  • Venous reflux develops when valves in the saphenous veins become damaged or blocked. (docveinmanagement.com)
  • When these valves in the saphenous veins are impaired, blood can pool in the leg, foot or toes. (docveinmanagement.com)
  • Usually the presence of varices on the outer side of the ankle, as shown, indicates that the vein is incompetent. (imsurgeon.com)
  • This invariably indicates the presence of an incompetent communicating vein at this site, which should be ligated and divided. (imsurgeon.com)
  • I've seen quite a few cases where a basilic vein transposition or cephalic vein transposition AVF requires an interposition graft due to vein not being quite long enough. (zhealthpublishing.com)
  • We aimed to assess the efficacy and safety profile of CAE in comparison to endovenous laser ablation (EVLA) in treating saphenous vein insufficiency. (ui.ac.id)
  • Large-caliber arteries on the left system, when grafted with a small-diameter vein, were associated with the best outcome. (austin.org.au)
  • The veins and the arteries work closely together to keep your vascular system functioning. (docveinmanagement.com)
  • A 54-year-old diabetic man underwent triple coronary artery bypass grafting using the left internal mammary artery (LIMA) and saphenous vein. (who.int)
  • Deep Vein Thrombosis (DVT) is a condition where a blood clot forms in the deep veins. (universityhealth.org)
  • The saphenous vein is generally acceptable as a conduit in the absence of other vascular pathologies in the leg (varicosities in the vein, venous insufficiency, previous deep vein thrombosis [DVT], or small lumen diameter) or overlying infection. (medscape.com)
  • Safety was determined by rates of periprocedural pain, skin pigmentation, nerve damage, phlebitis, deep vein thrombosis (DVT) and ecchymosis. (ui.ac.id)
  • Rates of phlebitis, deep vein thrombosis, and ecchymosis did not differ significantly between the 2 groups. (ui.ac.id)
  • Likewise, the SSV vein can be harvested either with an open procedure or endoscopically. (medscape.com)
  • 12. In-stent lesions for stent are located within an arterial or saphenous vein graft or stent used to treat a previous ISR. (who.int)
  • Using the conventional technique, the saphenous vein is harvested via a large open incision and excised in such a way that causes both vascular damage and wound healing complications. (rbccv.org.br)
  • Most varicose veins are reasonably benign, but severe varicosities can lead to major complications, due to the poor circulation through the affected limb. (mdwiki.org)
  • When venous insufficiency becomes a chronic problem, the saphenous vein can be shut down via endovenous ablation or removed with traditional vein stripping. (verywellhealth.com)
  • It also contributes to swelling in the ankles and legs (edema), restless legs syndrome (RLS), and varicose veins. (docveinmanagement.com)
  • The enlarged veins coming up from the lateral plantar surface of the foot (2) and some on the dorsum should be interrupted. (imsurgeon.com)
  • Using the bovine lateral saphenous vein bioassay, repetitive additions of 1x10-9 M ergovaline and 1x10-5 and 1x10-4 M lysergic acid resulted in contractile responses that did not increase with each addition. (usda.gov)
  • The objectives of this study were to determine if repetitive in vitro exposure of bovine lateral saphenous vein to either lysergic acid or ergovaline would result in an increasing contractile response and if a measurable bioaccumulation of the alkaloids in the vascular tissue occurs over time. (usda.gov)
  • V tu thetntervening tendon of the saphenous vein, which suspends the right strand, of inciilatiou. (wildwoodclinic.com)
  • Introduction: Cyanoacrylate embolization (CAE) is a novel non-thermal non-tumescent venous ablation technique that has shown promising results in treating saphenous vein insufficiency. (ui.ac.id)
  • To reach this vein, a surgical cut will be made along the inside of your leg, between your ankle and groin. (medlineplus.gov)
  • The Saphenous Vein Harvest Pad holds patient's legs and supports the upper thigh at the optimal position for assessment and harvest of the saphenous vein during coronary bypass surgery. (schuremed.com)
  • An example of a type of surgery where this vein is harvested is coronary bypass surgery . (verywellhealth.com)
  • Once the anesthetist is ready for surgery to start and the surgeon has confirmed the number of lengths (25 cm) of vein required, the vein harvest can begin. (medscape.com)
  • The saphenous vein is the most used conduit for coronary artery bypass surgery. (rbccv.org.br)
  • [1] Medical procedures include sclerotherapy , laser surgery , and vein stripping . (mdwiki.org)
  • [6] Varicose veins have been described throughout history and have been treated with surgery since at least A.D. 400. (mdwiki.org)
  • Randomized trial of vein versus dacron patching during carotid endarterectomy: long-term results. (qxmd.com)
  • Tumorcells were seen in the dermis, and the lumen, as well asoutside the wall of saphenous vein, but not in the epidermis.Only very few melanocytic granules were seen in a singlearea of a section. (who.int)
  • The saphenous vein was grafted to the left anterior descending artery in 557 (15%), to the diagonal artery in 669 (18%), to the obtuse marginal artery in 1300 (35%), to the right coronary artery in 409 (11%), and to the posterior descending artery in 780 (21%) cases. (austin.org.au)
  • The first group consists of 26 patients, undergone grafting through a double-Y incision and a single saphenous graft placed within the incision. (wjps.ir)