Any of the ducts which transport saliva. Salivary ducts include the parotid duct, the major and minor sublingual ducts, and the submandibular duct.
Tumors or cancer of the SALIVARY GLANDS.
Malignant neoplasms involving the ductal systems of any of a number of organs, such as the MAMMARY GLANDS, the PANCREAS, the PROSTATE, or the LACRIMAL GLAND.
Presence of small calculi in the terminal salivary ducts (salivary sand), or stones (larger calculi) found in the larger ducts.
A genus in the family Blattidae containing several species, the most common being P. americana, the American cockroach.
Tumors or cancer of the PAROTID GLAND.
Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).
"Salivary gland diseases refer to a group of medical conditions that affect the function, structure, or health of the salivary glands, leading to symptoms such as dry mouth, swelling, pain, and abnormal secretions."
One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)
A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
The largest of the three pairs of SALIVARY GLANDS. They lie on the sides of the FACE immediately below and in front of the EAR.
The channels that collect and transport the bile secretion from the BILE CANALICULI, the smallest branch of the BILIARY TRACT in the LIVER, through the bile ductules, the bile ducts out the liver, and to the GALLBLADDER for storage.
Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
The largest lymphatic vessel that passes through the chest and drains into the SUBCLAVIAN VEIN.

Dopamine stimulates salivary duct cells in the cockroach Periplaneta americana. (1/111)

This study examines whether the salivary duct cells of the cockroach Periplaneta americana can be stimulated by the neurotransmitters dopamine and serotonin. We have carried out digital Ca2+-imaging experiments using the Ca2+-sensitive dye fura-2 and conventional intracellular recordings from isolated salivary glands. Dopamine evokes a slow, almost tonic, and reversible dose-dependent elevation in [Ca2+]i in the duct cells. Upon stimulation with 10(-)6 mol l-1 dopamine, [Ca2+]i rises from 48+/-4 nmol l-1 to 311+/-43 nmol l-1 (mean +/- s.e.m., N=18) within 200-300 s. The dopamine-induced elevation in [Ca2+]i is absent in Ca2+-free saline and is blocked by 10(-)4 mol l-1 La3+, indicating that dopamine induces an influx of Ca2+ across the basolateral membrane of the duct cells. Stimulation with 10(-)6 mol l-1 dopamine causes the basolateral membrane to depolarize from -67+/-1 to -41+/-2 mV (N=10). This depolarization is also blocked by La3+ and is abolished when Na+ in the bath solution is reduced to 10 mmol l-1. Serotonin affects neither [Ca2+]i nor the basolateral membrane potential of the duct cells. These data indicate that the neurotransmitter dopamine, which has previously been shown to stimulate fluid secretion from the glands, also stimulates the salivary duct cells, suggesting that dopamine controls their most probable function, the modification of primary saliva.  (+info)

Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. (2/111)

Surfactant protein D (SP-D) is an oligomeric C type lectin that promotes phagocytosis by binding to microbial surface carbohydrates. A 340-kDa glycoprotein (gp-340) has been shown to bind SP-D in the presence of calcium but does so independently of carbohydrate recognition. This protein exists both in a soluble form and in association with the membranes of alveolar macrophages. The primary structure of gp-340 has been established by molecular cloning, which yielded a 7,686-bp cDNA sequence encoding a polypeptide chain of 2, 413 amino acids. The domain organization features 13 scavenger receptor cysteine-rich (SRCR) domains, each separated by an SRCR-interspersed domain, except for SRCRs 4 and 5, which are contiguous. The 13 SRCR domains are followed by two C1r/C1s Uegf Bmp1 domains separated by a 14th SRCR domain and a zona pellucida domain. gp-340 seems to be an alternative spliced form of DMBT1. Reverse transcription-PCR analysis showed that the main sites of synthesis of gp-340 are lung, trachea, salivary gland, small intestine, and stomach. Immunohistochemistry revealed strong staining for gp-340 in alveolar and other tissue macrophages. Immunostaining of the macrophage membrane was either uniform or focal in a way that suggested capping, whereas other macrophages showed strong intracellular staining within the phagosome/phagolysosome compartments. In some macrophages, SP-D and gp-340 were located in the same cellular compartment. Immunoreactive gp-340 was also found in epithelial cells of the small intestine and in the ducts of salivary glands. The distribution of gp-340 in macrophages is compatible with a role as an opsonin receptor for SP-D.  (+info)

Immunolocalization of anion exchanger AE2 and Na(+)-HCO(-)(3) cotransporter in rat parotid and submandibular glands. (3/111)

Salivary glands secrete K(+) and HCO(-)(3) and reabsorb Na(+) and Cl(-), but the identity of transporters involved in HCO(-)(3) transport remains unclear. We investigated localization of Cl(-)/HCO(-)(3) exchanger isoform AE2 and of Na(+)-HCO(-)(3) cotransporter (NBC) in rat parotid gland (PAR) and submandibular gland (SMG) by immunoblot and immunocytochemical techniques. Immunoblotting of PAR and SMG plasma membranes with specific antibodies against mouse kidney AE2 and rat kidney NBC revealed protein bands at approximately 160 and 180 kDa for AE2 and approximately 130 kDa for NBC, as expected for the AE2 full-length protein and consistent with the apparent molecular mass of NBC in several tissues other than kidney. Immunostaining of fixed PAR and SMG tissue sections revealed specific basolateral staining of PAR acinar cells for AE2 and NBC, but in SMG acinar cells only basolateral AE2 labeling was observed. No AE2 expression was detected in any ducts. Striated, intralobular, and main duct cells of both glands showed NBC expression predominantly at basolateral membranes, with some cells being apically stained. In SMG duct cells, NBC staining exhibited a gradient of distribution from basolateral localization in more proximal parts of the ductal tree to apical localization toward distal parts of the ductal tree. Both immunoblotting signals and immunostaining were abolished in preabsorption experiments with the respective antigens. Thus the mechanisms of fluid and anion secretion in salivary acinar cells may be different between PAR and SMG, and, because NBC was detected in acinar and duct cells, it may play a more important role in transport of HCO(-)(3) by rat salivary duct cells than previously believed.  (+info)

Uptake of cationized ferritin by the epithelium of the main excretory duct of the rat submandibular gland. (4/111)

Previous studies demonstrated that the main excretory duct (MED) of the rat submandibular gland can internalize exogenous protein in addition to reabsorbing and secreting electrolytes. However, more precise studies have not been conducted. The aim of this study was to elucidate the cell types responsible for endocytosis of an exogenous protein (ferritin) and to follow the movements of the endocytosed protein in the ductal epithelial cells. The MEDs of the right submandibular gland of male Wistar rats were exposed near the glands proper and cationized ferritin solution was injected into each MED through a fine glass cannula. The MEDs were removed at intervals after ferritin injection, fixed and examined by transmission electron microscopy. The epithelium of the MED of the rat submandibular gland was pseudostratified and consisted of light (types I and II), dark, tuft and basal cells. Uptake of ferritin by the light (types I and II) and dark cells occurred frequently. Small vesicles and multivesicular bodies containing ferritin particles were observed in the supra-nuclear and lateral nuclear cytoplasm. Endocytosis of tracers by tuft cells was rare. Some of the small vesicles and the multivesicular bodies were acid phosphatase-positive. By 60 min after treatment, ferritin-containing small vesicles and multivesicular bodies appeared in the basal cytoplasm. Ferritin particles were also observed in basal extracellular spaces. The light (types I and II), dark and tuft cells (latter rarely) participated in endocytosis of exogenous proteins in the epithelium of the MED of the rat submandibular gland. Almost all of the internalized proteins appeared to be processed by the lysosomal system, and some proteins were released into the extracellular spaces.  (+info)

Immunohistochemical localization of carbonic anhydrases I, II, and VI in the developing rat sublingual and submandibular glands. (5/111)

Carbonic anhydrase has been localized to the acini and ducts of mature rat salivary glands. This enzyme has been associated with ion transport, a prominent function of striated and excretory ducts in salivary glands, suggesting that it might be used as a marker of ductal differentiation. The purpose of this study was to immunohistochemically document developmental changes in carbonic anhydrase in the ducts of the rat sublingual and submandibular glands. Immunohistochemistry was performed with antibodies to human carbonic anhydrase isoenzymes I, II and VI on sections of sublingual and submandibular glands from rats at representative postnatal developmental ages. Reactions were weak in the ducts of both glands at 1 day, then progressively increased. By 42 days, reactions had the adult pattern of virtually none in the mucous or seromucous acini, moderate to strong in the striated and excretory ducts, and none to weak in the intercalated ducts. Weak to moderate reactions were observed in the granular convoluted tubules of the submandibular gland as they became recognizable at age 42 days. Reactions to carbonic anhydrase I and II antibodies also increased from none (1 day) to modest (42 days) in the demilunes of the sublingual gland. The order of reaction intensity of the antibodies was II > I > VI. When localized via these anti-human antibodies, carbonic anhydrase is a useful marker of the functional differentiation of the striated and excretory ducts of the developing rat sublingual and submandibular glands.  (+info)

Cell death during development of intercalated ducts in the rat submandibular gland. (6/111)

Programmed cell death, or apoptosis, occurs during the development of many tissues and organs in almost all multicellular organisms. Although apoptosis of salivary gland cells has been demonstrated in several pathological conditions, the role of apoptosis in the postnatal development of the salivary glands is unknown. We have studied the development of the rat submandibular gland (SMG) during its transition from the perinatal stage to the mature adult stage. Terminal tubule or Type I cells, which synthesize the secretory protein SMG-C, are prominent in the perinatal acini and are believed to form the intercalated ducts of the adult gland. Between 25 days and 30 days after birth, the number of Type I cells and their SMG-C immunoreactivity markedly decreased. Apoptotic cells in association with the developing intercalated ducts were labeled with the Terminal Deoxyribonucleotidyl Transferase-Mediated dUTP Nick End Labeling (TUNEL) method. Between 25 and 40 days of age, from 50 to 80% of the apoptotic cells in cryostat sections of the SMG were closely associated with the intercalated ducts. Electron microscopy showed that the Type I cells became vacuolated, their secretory granules were reduced in size and number, and the amount of rough endoplasmic reticulum was decreased. Cellular debris resembling apoptotic bodies was phagocytosed by macrophages and adjacent intercalated duct cells. These observations suggest that the loss of Type I cells and reduction of SMG-C immunoreactivity during development of the intercalated ducts of the adult rat SMG is due, at least in part, to apoptosis.  (+info)

Chloride channels and salivary gland function. (7/111)

Fluid and electrolyte transport is driven by transepithelial Cl- movement. The opening of Cl- channels in the apical membrane of salivary gland acinar cells initiates the fluid secretion process, whereas the activation of Cl- channels in both the apical and the basolateral membranes of ductal cells is thought to be necessary for NaCl re-absorption. Saliva formation can be evoked by sympathetic and parasympathetic stimulation. The composition and flow rate vary greatly, depending on the type of stimulation. As many as five classes of Cl- channels with distinct gating mechanisms have been identified in salivary cells. One of these Cl- channels is activated by intracellular Ca2+, while another is gated by cAMP. An increase in the intracellular free Ca2+ concentration is the dominant mechanism triggering fluid secretion from acinar cells, while cAMP may be required for efficient NaCl re-absorption in many ductal cells. In addition to cAMP- and Ca(2+)-gated Cl- channels, agonist-induced changes in membrane potential and cell volume activate different Cl- channels that likely play a role in modulating fluid and electrolyte movement. In this review, the properties of the different types of Cl- currents expressed in salivary gland cells are described, and functions are proposed based on the unique properties of these channels.  (+info)

Salivary gland P2 nucleotide receptors. (8/111)

The effects of ATP on salivary glands have been recognized since 1982. Functional and pharmacological studies of the P2 nucleotide receptors that mediate the effects of ATP and other extracellular nucleotides have been supported by the cloning of receptor cDNAs, by the expression of the receptor proteins, and by the identification in salivary gland cells of multiple P2 receptor subtypes. Currently, there is evidence obtained from pharmacological and molecular biology approaches for the expression in salivary gland of two P2X ligand-gated ion channels, P2Z/P2X7 and P2X4, and two P2Y G protein-coupled receptors, P2Y1 and P2Y2. Activation of each of these receptor subtypes increases intracellular Ca2+, a second messenger with a key role in the regulation of salivary gland secretion. Through Ca2+ regulation and other mechanisms, P2 receptors appear to regulate salivary cell volume, ion and protein secretion, and increased permeability to small molecules that may be involved in cytotoxicity. Some localization of the various salivary P2 receptor subtypes to specific cells and membrane subdomains has been reported, along with evidence for the co-expression of multiple P2 receptor subtypes within specific salivary acinar or duct cells. However, additional studies in vivo and with intact organ preparations are required to define clearly the roles the various P2 receptor subtypes play in salivary gland physiology and pathology. Opportunities for eventual utilization of these receptors as pharmacotherapeutic targets in diseases involving salivary gland dysfunction appear promising.  (+info)

Salivary ducts are the excretory tubules that transport saliva from the major and minor salivary glands to the oral cavity. The main function of these ducts is to convey the salivary secretions, which contain enzymes and lubricants, into the mouth to aid in digestion, speech, and swallowing.

There are two pairs of major salivary glands: the parotid glands and the submandibular glands. Each pair has its own set of ducts. The parotid gland's saliva is drained through the parotid duct, also known as Stensen's duct, which opens into the oral cavity opposite the upper second molar tooth. The submandibular gland's saliva is transported through the submandibular duct, or Wharton's duct, which empties into the floor of the mouth near the base of the tongue.

Minor salivary glands are scattered throughout the oral cavity and pharynx, and their secretions are drained via small ducts directly into the oral mucosa.

Salivary gland neoplasms refer to abnormal growths or tumors that develop in the salivary glands. These glands are responsible for producing saliva, which helps in digestion, lubrication of food and maintaining oral health. Salivary gland neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign neoplasms are slow-growing and typically do not spread to other parts of the body. They may cause symptoms such as swelling, painless lumps, or difficulty swallowing if they grow large enough to put pressure on surrounding tissues.

Malignant neoplasms, on the other hand, can be aggressive and have the potential to invade nearby structures and metastasize (spread) to distant organs. Symptoms of malignant salivary gland neoplasms may include rapid growth, pain, numbness, or paralysis of facial nerves.

Salivary gland neoplasms can occur in any of the major salivary glands (parotid, submandibular, and sublingual glands) or in the minor salivary glands located throughout the mouth and throat. The exact cause of these neoplasms is not fully understood, but risk factors may include exposure to radiation, certain viral infections, and genetic predisposition.

Carcinoma, ductal refers to a type of cancer that begins in the milk ducts (tubes that carry milk from the breast to the nipple). It is most commonly found in the breast and is often referred to as "invasive ductal carcinoma" when it has spread beyond the ducts into the surrounding breast tissue. Ductal carcinoma can also occur in other organs, such as the pancreas, where it is called "pancreatic ductal adenocarcinoma." This type of cancer is usually aggressive and can metastasize (spread) to other parts of the body.

Salivary duct calculi, also known as salivary gland stones or salivary duct stones, are small, hard deposits that form in the salivary glands or their ducts. These stones typically consist of calcium salts and other minerals, and they can range in size from tiny grains to larger pebbles.

Salivary duct calculi can cause a variety of symptoms, including pain, swelling, and difficulty swallowing. They may also lead to infection or inflammation of the salivary glands. In severe cases, surgery may be necessary to remove the stones and relieve the associated symptoms.

The formation of salivary duct calculi is thought to be related to a variety of factors, including dehydration, decreased saliva production, and changes in the composition of saliva. People who have certain medical conditions, such as gout or hyperparathyroidism, may also be at increased risk for developing these stones.

"Periplaneta" is a genus name that refers to a group of large, winged insects commonly known as cockroaches. The two most common species in this genus are the American cockroach (Periplaneta americana) and the German cockroach (Periplaneta germantica). These insects are typically found in warm, humid environments and can often be seen scurrying across floors or walls in homes, restaurants, and other buildings. They are known to carry diseases and can cause allergies and asthma attacks in some people.

Parotid neoplasms refer to abnormal growths or tumors in the parotid gland, which is the largest of the salivary glands and is located in front of the ear and extends down the neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign parotid neoplasms are typically slow-growing, painless masses that may cause facial asymmetry or difficulty in chewing or swallowing if they become large enough to compress surrounding structures. The most common type of benign parotid tumor is a pleomorphic adenoma.

Malignant parotid neoplasms, on the other hand, are more aggressive and can invade nearby tissues and spread to other parts of the body. They may present as rapidly growing masses that are firm or fixed to surrounding structures. Common types of malignant parotid tumors include mucoepidermoid carcinoma, adenoid cystic carcinoma, and squamous cell carcinoma.

The diagnosis of parotid neoplasms typically involves a thorough clinical evaluation, imaging studies such as CT or MRI scans, and fine-needle aspiration biopsy (FNAB) to determine the nature of the tumor. Treatment options depend on the type, size, and location of the neoplasm but may include surgical excision, radiation therapy, and chemotherapy.

Salivary glands are exocrine glands that produce saliva, which is secreted into the oral cavity to keep the mouth and throat moist, aid in digestion by initiating food breakdown, and help maintain dental health. There are three major pairs of salivary glands: the parotid glands located in the cheeks, the submandibular glands found beneath the jaw, and the sublingual glands situated under the tongue. Additionally, there are numerous minor salivary glands distributed throughout the oral cavity lining. These glands release their secretions through a system of ducts into the mouth.

Salivary gland diseases refer to a group of conditions that affect the function and structure of the salivary glands. These glands are responsible for producing saliva, which helps in digestion, lubrication, and protection of the mouth and throat. The major salivary glands include the parotid, submandibular, and sublingual glands.

There are several types of salivary gland diseases, including:

1. Salivary Gland Infections: These are usually caused by bacteria or viruses that infect the gland, ducts, or surrounding tissues. The most common infection is called sialadenitis, which can cause pain, swelling, redness, and difficulty swallowing.

2. Salivary Gland Stones (Sialolithiasis): These are small, hard deposits that form in the ducts of the salivary glands, causing blockages and leading to swelling, pain, and infection.

3. Salivary Gland Tumors: Both benign and malignant tumors can develop in the salivary glands. Benign tumors are usually slow-growing and cause localized swelling, while malignant tumors may be more aggressive and spread to other parts of the body.

4. Salivary Gland Dysfunction: This refers to conditions that affect the production or flow of saliva, such as Sjogren's syndrome, radiation therapy, dehydration, or certain medications.

5. Autoimmune Disorders: Conditions like Sjogren's syndrome, lupus, and rheumatoid arthritis can affect the salivary glands and cause inflammation, dry mouth, and other symptoms.

6. Salivary Gland Trauma: Injuries to the face or neck can damage the salivary glands and lead to swelling, bleeding, or decreased function.

Proper diagnosis and treatment of salivary gland diseases require a thorough evaluation by a healthcare professional, often involving imaging studies, laboratory tests, and biopsies. Treatment options may include antibiotics, surgery, radiation therapy, or changes in medication or lifestyle.

The submandibular glands are one of the major salivary glands in the human body. They are located beneath the mandible (jawbone) and produce saliva that helps in digestion, lubrication, and protection of the oral cavity. The saliva produced by the submandibular glands contains enzymes like amylase and mucin, which aid in the digestion of carbohydrates and provide moisture to the mouth and throat. Any medical condition or disease that affects the submandibular gland may impact its function and could lead to problems such as dry mouth (xerostomia), swelling, pain, or infection.

A pleomorphic adenoma is a type of benign (non-cancerous) tumor that typically develops in the salivary glands, although they can also occur in other areas such as the nasopharynx and skin. "Pleomorphic" refers to the diverse appearance of the cells within the tumor, which can vary in size, shape, and arrangement.

Pleomorphic adenomas are composed of a mixture of epithelial and mesenchymal cells, which can form glandular structures, squamous (scale-like) cells, and areas that resemble cartilage or bone. These tumors tend to grow slowly and usually do not spread to other parts of the body.

While pleomorphic adenomas are generally not dangerous, they can cause problems if they become large enough to press on surrounding tissues or structures. In some cases, these tumors may also undergo malignant transformation, leading to a cancerous growth known as carcinoma ex pleomorphic adenoma. Surgical removal is the standard treatment for pleomorphic adenomas, and the prognosis is generally good with proper management.

The parotid gland is the largest of the major salivary glands. It is a bilobed, accessory digestive organ that secretes serous saliva into the mouth via the parotid duct (Stensen's duct), located near the upper second molar tooth. The parotid gland is primarily responsible for moistening and lubricating food to aid in swallowing and digestion.

Anatomically, the parotid gland is located in the preauricular region, extending from the zygomatic arch superiorly to the angle of the mandible inferiorly, and from the masseter muscle anteriorly to the sternocleidomastoid muscle posteriorly. It is enclosed within a fascial capsule and has a rich blood supply from the external carotid artery and a complex innervation pattern involving both parasympathetic and sympathetic fibers.

Parotid gland disorders can include salivary gland stones (sialolithiasis), infections, inflammatory conditions, benign or malignant tumors, and autoimmune diseases such as Sjögren's syndrome.

Bile ducts are tubular structures that carry bile from the liver to the gallbladder for storage or directly to the small intestine to aid in digestion. There are two types of bile ducts: intrahepatic and extrahepatic. Intrahepatic bile ducts are located within the liver and drain bile from liver cells, while extrahepatic bile ducts are outside the liver and include the common hepatic duct, cystic duct, and common bile duct. These ducts can become obstructed or inflamed, leading to various medical conditions such as cholestasis, cholecystitis, and gallstones.

The pancreatic ducts are a set of tubular structures within the pancreas that play a crucial role in the digestive system. The main pancreatic duct, also known as the duct of Wirsung, is responsible for transporting pancreatic enzymes and bicarbonate-rich fluid from the pancreas to the duodenum, which is the first part of the small intestine.

The exocrine portion of the pancreas contains numerous smaller ducts called interlobular ducts and intralobular ducts that merge and ultimately join the main pancreatic duct. This system ensures that the digestive enzymes and fluids produced by the pancreas are effectively delivered to the small intestine, where they aid in the breakdown and absorption of nutrients from food.

In addition to the main pancreatic duct, there is an accessory pancreatic duct, also known as Santorini's duct, which can sometimes join the common bile duct before emptying into the duodenum through a shared opening called the ampulla of Vater. However, in most individuals, the accessory pancreatic duct usually drains into the main pancreatic duct before entering the duodenum.

Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.

The thoracic duct is the largest lymphatic vessel in the human body. It is a part of the lymphatic system, which helps to regulate fluid balance and immune function. The thoracic duct originates from the cisterna chyli, a dilated sac located in the abdomen near the aorta.

The thoracic duct collects lymph from the lower extremities, abdomen, pelvis, and left side of the thorax (chest). It ascends through the diaphragm and enters the chest, where it passes through the mediastinum (the central part of the chest between the lungs) and eventually drains into the left subclavian vein.

The thoracic duct plays a crucial role in transporting lymphatic fluid, which contains white blood cells, fats, proteins, and other substances, back into the circulatory system. Any obstruction or damage to the thoracic duct can lead to lymph accumulation in the surrounding tissues, causing swelling and other symptoms.

The salivary ducts (a duct of a salivary gland). These include: Stensen's duct Wharton's duct Major sublingual duct This ...
A salivary duct is a duct which brings saliva from a salivary gland to part of the digestive tract. In human anatomy there are ... Parotid duct Submandibular duct Major sublingual duct This article includes a list of related items that share the same name ( ...
... (also termed salivary duct stenosis) is narrowing of the duct of a major salivary gland. Strictures are ... Chronic inflammation of the duct system (sialodochitis) may cause some segments of the duct to narrow due to fibrosis, and ... Strictures are more common in the parotid duct system compared to the submandibular duct system. ... where there is pain and swelling of the involved salivary gland upon salivary stimulation with the sight, smell and taste of ...
... (SDC) is a rare type of aggressive cancer that arises from the salivary glands. It is predominantly ... Salivary gland Kinnera VS, Mandyam KR, Chowhan AK, Nandyala R, Bobbidi VP, Vutukuru VR (July 2009). "Salivary duct carcinoma of ... May 2015). "Salivary duct carcinoma: the predominance of apocrine morphology, prevalence of histologic variants, and androgen ... Rajesh NG, Prayaga AK, Sundaram C (2011). "Salivary duct carcinoma: correlation of morphologic features by fine needle ...
"Salivary duct stones". MedlinePlus Medical Encyclopedia. U.S. National Library of Medicine. Hayes JM, Ding SL (September 2012 ... It is also reported to be used for salivary stones and pancreatic stones. In the UK, the National Institute for Health and Care ...
A salivary diverticulum (plural diverticuli) is a small pouch or out-pocketing of the duct system of a major salivary gland. ... This irritation also causes inflammation of the duct openings of the minor salivary glands of the palate, and they become ... Affected individuals may "milk" the salivary gland to encourage flow of saliva through the duct. Sialolithiasis - although ... Salivary gland diseases (SGDs) are multiple and varied in cause. There are three paired major salivary glands in humans: the ...
They have salivary glands with salivary ducts. The excretory organs are only the left ones, in the pallial cavity. In the ...
Urban D, Rischin D, Angel C, D'Costa I, Solomon B (March 2015). "Abiraterone in metastatic salivary duct carcinoma". Journal of ... "Salivary duct carcinoma: the predominance of apocrine morphology, prevalence of histologic variants, and androgen receptor ... from 2010 suggests that ARs could be linked to the disease progression of triple-negative breast cancer and salivary duct ...
June 2015). "Molecular characterization of apocrine salivary duct carcinoma". The American Journal of Surgical Pathology. 39 (6 ... of salivary duct carcinomas. HER2 is colocalised and most of the time, coamplified with the gene GRB7, which is a proto- ...
"Molecular characterization of apocrine salivary duct carcinoma". The American Journal of Surgical Pathology. 39 (6): 744-52. ...
Recent studies suggest that HRAS mutations are common in thyroid, salivary duct carcinoma, epithelial-myoepithelial carcinoma, ... "Molecular characterization of apocrine salivary duct carcinoma". The American Journal of Surgical Pathology. 39 (6): 744-52. ...
The parotid duct, or Stensen duct, is a salivary duct. It is the route that saliva takes from the major salivary gland, the ... The lower buccal nerve runs inferiorly along the duct.[citation needed] Blockage, whether caused by salivary duct stones or ... The parotid duct is formed when several interlobular ducts, the largest ducts inside the parotid gland, join. It emerges from ... Parotid duct Parotid duct Parotid duct Parotid gland Parotitis Nanci A (2013). Ten Cate's Oral Histology: Development, ...
He also described the ducts of the submaxillary salivary glands. His brother was the author Giovanni Filoteo Achillini, and his ...
Ducts of Rivinus: The collective name for the minor sublingual salivary ducts. Rivina, a genus of flowering plants in family ...
... may be associated with salivary duct strictures and salivary stones. It is common in both the parotid glands and ... Sialodochitis (also termed ductal sialadenitis), is inflammation of the duct system of a salivary gland. This is compared to ... It may appear on a CT scan or MRI scan as enhancement and dilation of the duct (sialectasis). On sialography, it may appear as ... in which there is sudden swelling of the salivary glands. It is associated with other allergic conditions such as asthma, ...
Cook DI, Dinudom A, Komwatana P, Kumar S, Young JA (2002). "Patch-clamp studies on epithelial sodium channels in salivary duct ... in the collecting ducts of the kidneys, therefore opposing the actions of aldosterone and increasing salt excretion. In ...
In about February 2021, Poulton was diagnosed with salivary duct cancer. Despite treatment, in about May 2021, it had ...
... is cystic dilation of the ducts of salivary glands. It may be caused by salivary duct strictures or stones (sialolithiasis). It ...
This redirects the duct from the parotid salivary gland to the eye. Saliva replaces the tears. Dogs with cherry eye should have ... There are methods to partially or completely close the tear ducts. This blocks the flow of tears into the nose, and thus more ... This shrinks the drainage area tissues and causes scarring, which closes the tear duct. There is evidence that long‐chain omega ... A surgery known as parotid duct transposition is used in some extreme cases where medical treatment has not helped. ...
... is hyperplasia of the terminal duct of salivary glands. There are two types: Acinar adenomatoid ... hyperplasia Ductal adenomatoid hyperplasia Eveson JW; Speight PM (February 2006). "Non-neoplastic lesions of the salivary ...
"Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts". Journal of Cellular ... Rab11FIP5 is also suggested to be involved in aiding salivary epithelial cells to adjust to extracellular pH. V-ATPase, a ... When Rab11FIP5 is knocked down, salivary cells cannot correctly translocate V-ATPase to the plasma membrane in response to ...
These red dots represent the ducts of minor salivary glands which have become inflamed by heat. The condition is painless. If a ... There may be squamous metaplasia of excretory ducts, which results in the visible papules if the ducts become hyperplastic. ... Neutrophils may fill some ducts. It is characterized as a "fissured" or "dried mud" appearance from excess keratin production ...
The submandibular duct (also Wharton's duct or historically submaxillary duct) is one of the salivary excretory ducts. It is ... The submandibular duct arises from deep part of submandibular gland, a salivary gland. It begins by numerous branches from the ... The submandibular duct may be duplicated on one side or both sides, creating an accessory submandibular duct. Rarely, it may ... Rarely, the submandibular duct may not perforate into the mouth. Surgery may be used to repair this birth defect. The exit of ...
There is also irregular salivary duct stricture (narrowing) of the duct, which creates an appearance known as "sausage link" ... the duct is dilated using graded lacrimal probes, a cannula then is inserted in this salivary gland duct's opening in the mouth ... It usually involves the injection of a small amount of contrast medium into the salivary duct of a single gland, followed by ... Besides, when interventional proecudre is planned such as stone removal from salivary ducts or dilatation of the strictures in ...
An accessory salivary gland is ectopic salivary gland tissue with a salivary gland duct system. The most common location of ... Salivary gland heterotopia is where salivary gland acini cells are present in an abnormal location without any duct system. The ... Salivary gland neoplasm occurrence within heterotopic salivary gland tissue is rare. Stafne defect Barnes L (2008). Surgical ... Any disease process which affects the salivary glands, including cancer, may also occur within an accessory salivary gland ...
"Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+". Proc. Natl. Acad. Sci. U.S.A. 95 ...
... is congenital blockage or absence of the orifice of a major salivary gland duct or part of the duct ... The submandibular salivary gland duct is usually involved, having failed to cannulate during embryological development. The ... ISBN 978-93-5025-374-8. v t e (Salivary gland pathology, All stub articles, Disease stubs, Human reproduction stubs). ... Graamans K; van den Hans A (6 December 2012). Diagnosis of salivary gland disorders. Springer Science & Business Media. p. 115 ...
Salivary stones (also called sialolithiasis, or salivary duct calculus) are mainly made of calcium, but do not indicate any ... Ultrasound waves break up the stones, and the fragments flush out of the salivary duct. Chronic nonspecific parotitis: This ... Salivary Gland Stones (Salivary Calculi) Accessed March 20, 2008. Yu, Chuangqi; Zheng, Lingyan; Yang, Chi; Shen, Ning (2008). " ... Other causes can be duct stricture (narrowing of the duct), infection or injury. Symptoms may include recurrent swelling, pain ...
The virus is actively transported into the accessory salivary gland to be released into salivary canals and ducts. The virus is ...
Salivary stones (Sialolith) may be evident with cystic dilation of the salivary ducts and periductal fibrosis. Mucus ... This can be a result of obstruction of salivary ducts by microliths (due to associated intercurrent infections), or a result of ... It was thought that morphological characteristics of the salivary ducts could also be a contributing factor, as stagnation of ... Pus suppuration from major salivary gland duct openings may occur spontaneously or after manipulation of the affected gland. ...
One pair of large salivary glands discharges into the oesophagus via narrow salivary gland ducts directly behind the pharynx. ... Anteriorly, the long and highly coiled, muscular ejaculatory duct arises from the prostate. The ejaculatory duct enters the ... The renopericardial duct is connected to the narrow lumen in the anterior part of the kidney. The connection between the kidney ... The paraprostatic duct enters the basal finger approximately in the middle of the muscle and opens terminally via a hollow ...
The salivary ducts (a duct of a salivary gland). These include: Stensens duct Whartons duct Major sublingual duct This ...
Salivary duct stones are a type of salivary gland disorder. ... Salivary duct stones are a type of salivary gland disorder. ... Salivary duct stones are deposits of minerals in the ducts that drain the salivary glands. ... Salivary duct stones are deposits of minerals in the ducts that drain the salivary glands. ... Salivary duct stones are deposits of minerals in the ducts that drain the salivary glands. Salivary duct stones are a type of ...
Salivary duct stones are masses of crystallized minerals that form in the tubes that saliva passes through after its made in ... the salivary duct stone is removed without any complications. If you continue to develop salivary duct stones or salivary gland ... Its the most common cause of blockage in the salivary ducts.. Because salivary duct stones cause mouth pain, both doctors and ... You have three pairs of major salivary glands in your mouth. Salivary duct stones occur most often in the ducts connected to ...
Salivary Gland, Duct - Metaplasia, Squamous Narrative. Comment:. Metaplasia is a change in which one terminally differentiated ... Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 1). The ... Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 3). The ... Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 5). The ...
... retained salivary stent) return to: Sialendoscopy SEE IMAGES AND VIDEO BELOW see also: Salivary Gland Anatomic Anomalies and ... Submandibular Duct Foreign Body (retained salivary stent) last modified on: Mon, 11/05/2018 - 11:10. ... Submandibular Duct Foreign Body (retained salivary stent). return to: Sialendoscopy SEE IMAGES AND VIDEO BELOW ... Cannulation of duct orifice successful as was entry into duct through floor of mouth incison through previous scar overlying ...
Salivary Ducts. Lip. Tooth. Dentition, Permanent. Tongue. Palate. Uvula. Cattle. Part of Book The viscera of the human body : ... Artery and salivary duct from the parotid gland of a fetal calf, shown in isolation. Mouth shown open and intact with lips, ... Edited by Jones Quain and W.J. Erasmus Wilson. » Mouth, lips and salivary ducts ...
The parotid glands are the largest salivary glands in humans and are frequently involved in disease processes. Approximately 25 ... Salivary duct carcinoma. Salivary duct carcinoma is a rare and highly aggressive tumor. Small cell carcinoma exists as 2 types ... Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg. 1986 Jan-Feb. 8(3):177-84. [QxMD ... Malignant salivary tumors--analysis of prognostic factors and survival. Head Neck Surg. 1986 Nov-Dec. 9(2):82-92. [QxMD MEDLINE ...
What are the ducts of salivary glands?. The ducts of the salivary glands allow the passage of salivary juice from the glands to ... What does the submandibular duct do?. The submandibular duct, also called the Whartons duct, is the excretory duct of the ... What are the 3 salivary glands and their ducts?. The three major salivary glands are the parotid, submandibular, and sublingual ... called salivary ducts, near your upper teeth, submandibular under your tongue, and the sublingual through many ducts in the ...
Salivary Duct Stones; Sialolithiasis, Ductal. On-line free medical diagnosis assistant. Ranked list of possible diseases from ...
Research Talk: "Salivary Ducts - Linking Structure to Function". Amanda Wahl - Laboratory of Dr. David Yule ...
During the surgery, the instru ment is inserted into the duct of the salivary gland, and the stone is removed without any ... The father of two was diagnosed with five stones in his salivary ducts - a relatively less known condition called ... The conventional treatment for strictures or narrowing of glandular ducts and stones in the salivary glands is either ... Salivary glands are founds in three pairs -parotid glands behind the lower jaw, submandibular glands on the floor of the mouth ...
A salivary gland stone is a calcified structure which forms inside a salivary gland or duct. It can block the flow of saliva ... Salivary Duct Stones. A salivary gland stone is a calcified structure that forms inside a salivary gland or duct. It can block ... Where Do Salivary Duct Stones Occur?. There are three pairs of major salivary glands in the mouth. Salivary duct stones most ... 1. How does a salivary duct stone feel?. The main symptom of salivary duct stones is a pain in the face, mouth, or neck that ...
Salivary cysts following parotid duct translocation for sialorrhea. / Tunkel, D. E.; Furin, M. J. In: Otolaryngology - Head and ... Salivary cysts following parotid duct translocation for sialorrhea. Otolaryngology - Head and Neck Surgery. 1991;105(1):127-129 ... Tunkel, D. E. ; Furin, M. J. / Salivary cysts following parotid duct translocation for sialorrhea. In: Otolaryngology - Head ... Tunkel, D. E., & Furin, M. J. (1991). Salivary cysts following parotid duct translocation for sialorrhea. Otolaryngology - Head ...
Do you qualify for these Salivary Duct Carcinoma studies? Were researching treatments for 2022. ... Salivary Duct Carcinoma clinical trials at UCSF 1 in progress, 0 open to eligible people ... Our lead scientists for Salivary Duct Carcinoma research studies include David Oh. ... and Advanced Salivary Gland Cancers (SGC) Sorry, in progress, not accepting new patients ...
N2 - Salivary duct carcinoma (SDC) is an aggressive, uncommon tumor histologically comparable to high-grade mammary ductal ... AB - Salivary duct carcinoma (SDC) is an aggressive, uncommon tumor histologically comparable to high-grade mammary ductal ... Salivary duct carcinoma (SDC) is an aggressive, uncommon tumor histologically comparable to high-grade mammary ductal carcinoma ... abstract = "Salivary duct carcinoma (SDC) is an aggressive, uncommon tumor histologically comparable to high-grade mammary ...
The androgen-androgen receptor (AR) axis may be involved in malignant phenotypes of salivary duct carcinoma (SDC) cells and ... The androgen-androgen receptor (AR) axis may be involved in malignant phenotypes of salivary duct carcinoma (SDC) cells and ... The androgen-androgen receptor (AR) axis may be involved in malignant phenotypes of salivary duct carcinoma (SDC) cells and ... The androgen-androgen receptor (AR) axis may be involved in malignant phenotypes of salivary duct carcinoma (SDC) cells and ...
Congenital malformations of salivary glands and ducts. Q387. Congenital pharyngeal pouch. Q388. Other congenital malformations ...
Salivary Duct Stones. *Sensitive Teeth *Sleep Apnea. *Soft Tissue Infection. *Stained Teeth ...
N2 - Objective: Salivary duct carcinoma (SDC) is a highly aggressive and uncommon tumor arising not only de novo but also in ... AB - Objective: Salivary duct carcinoma (SDC) is a highly aggressive and uncommon tumor arising not only de novo but also in ... Objective: Salivary duct carcinoma (SDC) is a highly aggressive and uncommon tumor arising not only de novo but also in ... abstract = "Objective: Salivary duct carcinoma (SDC) is a highly aggressive and uncommon tumor arising not only de novo but ...
Cutaneous lymphangitis carcinomatosa in salivary duct carcinoma. Uijen MJ, Weijers JA, Lassche G, van Ravensteijn SG, van Rijk ... Salivary gland carcinoma]. Lassche G, van Engen-van Grunsven ACH, Honings J, Dijkema T, Weijs WLJ, van Herpen CML. Lassche G, ... Advances and challenges in precision medicine in salivary gland cancer. Lassche G, van Boxtel W, Ligtenberg MJL, van Engen-van ... Development and characterization of patient-derived salivary gland cancer organoid cultures. Lassche G, van Boxtel W, Aalders ...
By the salivary ducts. How long does it take for plaque to calcify (mineralize)? 2-days up to 50%. ...
High-throughput profiling identifies clinically actionable mutations in salivary duct carcinoma. J. Transl. Med. 12, 299 (2014 ...
Salivary Duct Stones ... View other providers who treat Salivary Gland Stones and ...
This redirects the duct from the parotid salivary gland to the eye. Saliva replaces the tears. Dogs with cherry eye should have ... In each eye, there are two puncta[57] - little openings that drain tears into the tear ducts.[4] There are methods to partially ... A surgery known as parotid duct transposition is used in some extreme cases where medical treatment has not helped. ... or completely close the tear ducts.[16] This blocks the flow of tears into the nose, and thus more tears are available to the ...
Salivary stones are rarely serious, and a person can often remove them at home. Learn how to get rid of them and when to see a ... Stones can sometimes form in the salivary glands of the mouth. If a stone becomes large enough, it can block the gland, which ... Salivary stones are small deposits of calcium and other minerals. They can form in the ducts of any type of salivary gland. ... Salivary stones can form in the ducts of any salivary gland. Image credit: James Heilman, MD, 2012. ...
Elderly Man Develops Facial Plaque After Salivary Duct Carcinoma Diagnosis Clinicians consider a number of differential ...
... and fuse together at the bodys midline to form the biluminal medial duct. This duct drains into the salivary pump. The ... The ducts of either side consist of at least four components-two gland ducts, one lateral duct, and one postmedial duct. Gland ... The biluminal lateral duct merges into the uniluminal postmedial duct. The lateral and postmedial ducts make intimate contact ... Ultrastructural Studies of the Salivary Duct System in the Whitefly Vector Bemisia tabaci (Aleyrodidae: Hemiptera) ...
Nitrate and nitrite concentration in human saliva collected from salivary ducts. J. Fd. Hyg. Soc., Japan, 16: 89. JAHREIS, G., ... Nitrate undergoes active secretion in humans not only in the salivary duct cells but also in the gastric pariental cells and, ... Salivary nitrate levels were found to be generally higher with increasing adult age (Forman et al., 1985). However, salivary ... salivary flow as well as reduced microbial activity (Eisenbrand et al., 1980). Salivary nitrite levels were generally higher in ...
  • Salivary duct carcinoma (SDC) is an aggressive, uncommon tumor histologically comparable to high-grade mammary ductal carcinoma. (elsevierpure.com)
  • The androgen-androgen receptor (AR) axis may be involved in malignant phenotypes of salivary duct carcinoma (SDC) cells and therefore may be a new target for SDC treatment. (elsevierpure.com)
  • Objective: Salivary duct carcinoma (SDC) is a highly aggressive and uncommon tumor arising not only de novo but also in pleomorphic adenoma. (fujita-hu.ac.jp)
  • Salivary gland carcinoma]. (nih.gov)
  • Cutaneous lymphangitis carcinomatosa in salivary duct carcinoma. (nih.gov)
  • Background: The most common type of carcinoma ex pleomorphic adenoma (CPA) is histologically equivalent to salivary duct carcinoma, which has an apocrine phenotype. (koreamed.org)
  • The father of two was diagnosed with five stones in his salivary ducts - a relatively less known condition called Sialolithiasis. (aarogya.com)
  • When they block the salivary glands, this is known as sialolithiasis. (medicalnewstoday.com)
  • For oral and maxillofacial surgery (OMFS) KARL STORZ has developed miniature endoscopes and instruments that can diagnose specific pathologies, as well as perform endoscopic treatment of salivary duct stenosis and sialolithiasis, using stone baskets, microdrills, laser as well additional instruments, which is a minimally invasive alternative to open salivary gland surgery. (karlstorz.com)
  • In some countries, maxillofacial surgeons are also involved in the primary treatment of neoplasm involving the salivary glands. (medscape.com)
  • Stones can also form in the ducts connected to the parotid glands, which are located on each side of your face in front of your ears. (healthline.com)
  • The parotid glands are the largest salivary glands in humans and are frequently involved in disease processes. (medscape.com)
  • Salivary glands are founds in three pairs -parotid glands behind the lower jaw, submandibular glands on the floor of the mouth, and sublingual glands below the tongue. (aarogya.com)
  • Parotitis is an inflammation of one or both parotid glands , the major salivary glands located on either side of the face, in humans.Acute suppurative parotitis is a very painful bacterial infection of the gland. (health-care-articles.info)
  • The largest salivary glands are the parotid glands in front of the ears, the sublingual glands underneath the tongue, and the submandibular glands beneath the lower jaw. (learninggnm.com)
  • The parotid glands, the largest pair of salivary glands, lie just behind the angle of the jaw, below and in front of the ears. (msdmanuals.com)
  • Jakob JA, Kies MS, Glisson BS, Kupferman ME, Liu DD, Lee JJ, El-Naggar AK, Gonzalez-Angulo AM, Blumenschein GR . A Phase II study of Gefitinib in Patients with Advanced Salivary Gland Cancers. (mdanderson.org)
  • The stone is often referred to as salivary duct calculus and mainly occurs in middle-aged adults. (healthline.com)
  • The association of clinical and radiographic findings led to the diagnosis of salivary calculus. (bvsalud.org)
  • Diagnosis of a kinking Stensen's duct is aided with salivary endoscopy and imaging to determine the precipitating pathology. (karger.com)
  • [ 1 ] This article reviews basic salivary anatomy and physiology, several important diseases affecting the glands, salivary constituents as measures of health, trends in diagnosis, and the management of xerostomia and drooling. (medscape.com)
  • The chemicals in saliva can form a hard crystal that can block the salivary ducts. (medlineplus.gov)
  • When these stones block the salivary ducts, saliva builds up in the glands, making them swell. (medicoverhospitals.in)
  • 2] However, the retention cyst is a true cyst due to an epithelial proliferation of the exit ducts that generates an obstruction of the salivary flow. (bvsalud.org)
  • What are the symptoms of a blocked salivary gland? (blfilm.com)
  • Contact your provider if you have symptoms of salivary duct stones. (medlineplus.gov)
  • What are the symptoms of salivary duct stones? (healthline.com)
  • Symptoms of salivary duct stones include getting pain in the face, mouth, or neck that becomes worse just before or during meals. (medicoverhospitals.in)
  • In this article, we explain what salivary stones are and discuss their symptoms and causes. (medicalnewstoday.com)
  • Salivary stones do not usually cause symptoms when they are forming, and they can sometimes disappear on their own. (medicalnewstoday.com)
  • Often there are additional symptoms, such as arthritis, enlarged lymph nodes, or enlarged salivary glands. (hss.edu)
  • Squamous metaplasia is usually the result of chronic irritation, but it can have other causes (e.g., hypovitamnosis A). In the salivary ducts, metaplasia of the normally cuboidal ductal epithelium to stratified squamous epithelium has been seen in response to chemicals, ionizing radiation, viral infections, vitamin A deficiency, and blockage of ducts by salivary calculi. (nih.gov)
  • These include: Stensen's duct Wharton's duct Major sublingual duct This article includes a list of related items that share the same name (or similar names). (wikipedia.org)
  • Stensen's duct drains the parotid gland opposite the upper second molar. (blfilm.com)
  • To investigate 3 cases of chronic parotitis secondary to an acute bend in Stensen's duct caused by an enlargement of the masseteric space. (karger.com)
  • Salivary endoscopy showed an acute bend in Stensen's duct secondary to a mass effect. (karger.com)
  • Salivary endoscopy revealed bilateral kinking of Stensen's duct with jaw closure. (karger.com)
  • According to research from 2012 , more than 80 percent of salivary stones form in the submandibular gland, while 6-15 percent occur in the parotid gland, and 2 percent are in the sublingual and minor salivary glands. (medicalnewstoday.com)
  • Dentists are involved with aspects of salivary gland function in several ways, such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with salivary problems, in the treatment of caries and periodontal disease resulting from decreased salivary flow, and in controlling salivation during restorative procedures. (medscape.com)
  • It's a very common exophytic lesion resulting from a salivary accumulation, due to an alteration of the minor salivary gland.They can be categorized according to their etiology: they may occur from extravasation or retention of the secretion.The main one is the extravasation mucocele caused by traumatic rupture of the gland's epithelium spilling out the mucus in the extra-glandular space. (bvsalud.org)
  • When saliva cannot exit a blocked duct, it backs up into the gland. (medlineplus.gov)
  • When saliva cannot flow through a duct, it backs up in the gland, causing swelling and pain. (healthline.com)
  • The parasympathetic and sympathetic nervous systems stimulate the salivary glands. (blfilm.com)
  • Autonomic innervation of the salivary glands involves both parasympathetic and sympathetic input. (medscape.com)
  • How do I know if I have a salivary gland infection? (blfilm.com)
  • Salivary stones can sometimes also lead to infection in or around the affected gland. (medicalnewstoday.com)
  • The team of experts at the UPMC Salivary Gland Stone and Infection Center diagnose and treat people who have conditions affecting the salivary glands. (upmc.com)
  • We also work to advance the practice of minimally invasive surgical techniques to remove stones through the salivary ducts. (upmc.com)
  • Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
  • It's the most common cause of blockage in the salivary ducts. (healthline.com)
  • Spit (saliva) is produced by the salivary glands in the mouth. (medlineplus.gov)
  • Because salivary duct stones cause mouth pain, both doctors and dentists can diagnose this condition and provide medical treatment if necessary. (healthline.com)
  • The main symptom of salivary duct stones is pain in your face, mouth, or neck that becomes worse just before or during meals. (healthline.com)
  • You have three pairs of major salivary glands in your mouth. (healthline.com)
  • Cannulation of duct orifice successful as was entry into duct through floor of mouth incison through previous scar overlying previous entry site into duct. (uiowa.edu)
  • submandibular duct (Wharton duct): connects the submandibular gland to the floor of the mouth. (blfilm.com)
  • Wharton's duct drains the submandibular and some of the sublingual glands into the floor of the mouth near the frenulum of the tongue. (blfilm.com)
  • Each submandibular duct begins at the right and left sides of the mouth. (blfilm.com)
  • They all secrete saliva into your mouth, the parotid through tubes that drain saliva, called salivary ducts, near your upper teeth, submandibular under your tongue, and the sublingual through many ducts in the floor of your mouth. (blfilm.com)
  • During the surgery, the instru ment is inserted into the duct of the salivary gland, and the stone is removed without any incision on the face or the mouth. (aarogya.com)
  • Salivary stones are small stones that form in the glands of the mouth. (medicalnewstoday.com)
  • The salivary glands in the mouth produce a liquid called saliva. (medicalnewstoday.com)
  • The mouth contains hundreds of minor, or small, salivary glands. (medicalnewstoday.com)
  • The salivary glands are located in several parts of the mouth. (learninggnm.com)
  • The submucosa of the mouth and pharynx (including the lips, gums, palate, tongue, salivary glands, tonsils, and throat) consists of intestinal cylinder epithelium , originates from the endoderm and is therefore controlled from the brainstem. (learninggnm.com)
  • In addition to these major glands, many tiny salivary glands are distributed throughout the mouth. (msdmanuals.com)
  • However, not all cases of dry mouth are caused by salivary gland malfunction. (msdmanuals.com)
  • However, the kinetics of nitrate secretion in rat saliva appear to have been less well studied than in humans, and even less is known concerning salivary secretion in mice. (inchem.org)
  • In the dog, in addition to strong salivary secretion, large quantities of nitrate were excreted in the bile following i.v. administration of nitrite, thus confirming this pathway of excretion as well as oxidation of nitrite in vivo (Walker, in press). (inchem.org)
  • Mumps is an acute viral illness caused by a paramyxovirus that typically presents as swelling of the parotid (parotitis) or other salivary gland[s]. (cdc.gov)
  • There is a sense of disbelief among patients when we tell them about stones in the salivary glands. (aarogya.com)
  • Background/Aim: Androgens are known to play a critical role in prostate cancer progression, but their effect on malignant phenotypes in salivary gland cancer is unclear. (elsevierpure.com)
  • This study on 279 tumours of the salivary glands was conducted to analyse whether the assessment of DNA ploidy by flow cytometry may assist histopathology in discriminating benign from malignant types of tumours. (researchgate.net)
  • Twelve of 50 malignant salivary gland tumours were aneuploid. (researchgate.net)
  • The most obvious value of DNA flow cytometry in salivary gland tumours is thus its contribution to assist histopathology in identifying potentially malignant lesions. (researchgate.net)
  • Salivary duct stones are deposits of minerals in the ducts that drain the salivary glands. (medlineplus.gov)
  • Additionally, it's adjacent to salivary glands and ducts that drain these glands. (koaa.com)
  • This is an X-ray with dye in it that travels through the salivary ducts and detects dryness. (hss.edu)
  • Significant abnormality or disease of the salivary glands, such as that associated with Sjögren syndrome or neoplasm, necessitates additional evaluation by an otolaryngologist or an otolaryngologist/head and neck surgeon for comprehensive treatment of the gland pathology itself. (medscape.com)
  • What is Wharton's duct? (blfilm.com)
  • Wharton's duct is a thin tube, about 5 cm in length, and an essential carrier of your saliva. (blfilm.com)
  • The submandibular duct, also called the Wharton's duct, is the excretory duct of the gland. (blfilm.com)
  • Salivary stones most often affect the submandibular glands. (medlineplus.gov)
  • Salivary duct stones occur most often in the ducts connected to your submandibular glands. (healthline.com)
  • Artery and salivary duct from the parotid gland of a fetal calf, shown in isolation. (utoronto.ca)
  • The submandibular duct openings are underneath the tongue. (blfilm.com)
  • Saliva flow can be measured, or doctors may biopsy salivary gland tissue. (msdmanuals.com)
  • Treatment for salivary duct stones involves activities to get rid of the stones. (healthline.com)
  • This involves removing a small salivary gland from inside your lip and examining it under the microscope for inflammatory cells in a certain pattern. (hss.edu)
  • Salivary gland malfunction is more common among adults and usually involves too little saliva production. (msdmanuals.com)
  • Advances and challenges in precision medicine in salivary gland cancer. (nih.gov)
  • Development and characterization of patient-derived salivary gland cancer organoid cultures. (nih.gov)
  • 7. Primary cancer of the Bile ducts. (cdc.gov)
  • The three major salivary glands are the parotid, submandibular, and sublingual glands. (blfilm.com)
  • The salivary system is composed of 3 major gland sets and multiple minor glands. (medscape.com)
  • More recent research, however, suggests that salivary function in the major glands may diminish with increasing age. (medscape.com)
  • Massaging the gland with heat -- The provider or dentist may be able to push the stone out of the duct. (medlineplus.gov)
  • The goal is to increase saliva production and force the stone out of your duct. (healthline.com)
  • If you can't get the stone out at home, your doctor or dentist can try to push it out by pressing on both sides of the duct. (healthline.com)
  • Retained 20 gauge angiocatheter in submandibular duct placed after ductoplasty with stone removal. (uiowa.edu)
  • The most commonly accepted one is that food particles enter the ducts and there is salt deposition around them, leading to formation of a stone. (aarogya.com)
  • A salivary gland stone is a calcified structure that forms inside a salivary gland or duct. (medicoverhospitals.in)
  • 1. How does a salivary duct stone feel? (medicoverhospitals.in)
  • 2. Can you squeeze out a salivary stone? (medicoverhospitals.in)
  • Gently massaging the affected area may relieve pain and encourage the stone to pass through the salivary duct. (medicalnewstoday.com)
  • A technique called sialendoscopy, can diagnose and treat stones in the salivary gland duct using very small cameras and instruments. (medlineplus.gov)
  • [ 3 ] Testosterone circulating in the body readily diffuses across capillaries and salivary ducts, resulting in a salivary fraction containing free unbound testosterone. (medscape.com)