AnatomyOrganismsDiseasesChemicals and Drugs
SalicylatesSodium SalicylateSalicylic AcidGentisatesAspirinAnti-Inflammatory Agents, Non-SteroidalHydroxybenzoatesBenzoic AcidCatecholsMixed Function OxygenasesTinnitusPseudomonasReye SyndromeChorismic AcidCyclooxygenase InhibitorsCatechol 1,2-DioxygenaseGaultheriaDioxygenasesPhenylbutazoneHair Cells, Auditory, OuterBenzoatesNaphthalenesPhenacetinBenzyl Alcohols
Salicylates
The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
Sodium Salicylate
A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)
Salicylic Acid
A compound obtained from the bark of the white willow and wintergreen leaves. It has bacteriostatic, fungicidal, and keratolytic actions.
Gentisates
Salts and esters of gentisic acid.
Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Hydroxybenzoates
Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.
Benzoic Acid
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
Catechols
A group of 1,2-benzenediols that contain the general formula R-C6H5O2.
Mixed Function Oxygenases
Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Tinnitus
A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.
Pseudomonas
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.
Reye Syndrome
A form of encephalopathy with fatty infiltration of the LIVER, characterized by brain EDEMA and VOMITING that may rapidly progress to SEIZURES; COMA; and DEATH. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and CARNITINE metabolism.
Chorismic Acid
A cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC AMINO ACIDS.
Cyclooxygenase Inhibitors
Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
Catechol 1,2-Dioxygenase
An enzyme that catalyzes the oxidation of catechol to muconic acid with the use of Fe3+ as a cofactor. This enzyme was formerly characterized as EC 1.13.1.1 and EC 1.99.2.2.
Gaultheria
A plant genus of the family ERICACEAE. The common name of "wintergreen" is also used for PYROLA and "snowberry" is also used for SYMPHORICARPOS.
Dioxygenases
Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS.
Phenylbutazone
A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
Hair Cells, Auditory, Outer
Sensory cells of organ of Corti. In mammals, they are usually arranged in three or four rows, and away from the core of spongy bone (the modiolus), lateral to the INNER AUDITORY HAIR CELLS and other supporting structures. Their cell bodies and STEREOCILIA increase in length from the cochlear base toward the apex and laterally across the rows, allowing differential responses to various frequencies of sound.
Benzoates
Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure.
Naphthalenes
Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
Phenacetin
A phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. (From Smith and Reynard, Textbook of Pharmacology,1991, p431)
Benzyl Alcohols
Alcohols derived from the aryl radical (C6H5CH2-) and defined by C6H5CHOH. The concept includes derivatives with any substituents on the benzene ring.

Perinatal nephropathies. (1/1030)

The purpose of this paper is to review the development of the mammalian kidney and to assess the influence that various perinatal manipulations may have on the developmental process either morphologically or functionally. Immature kidneys in general have less functional capacity than adult kidneys and a low rate of glomerular filtration, perhaps related to renal blood flow, which appears to limit the disposition of a fluid or solute load. Tubular reabsorption is also limited leading to the urinary loss of glucose, amino acids, bicarbonate and phosphate. Although the relatively low function of the immature kidney is a normal part of development, its capacity to respond under conditions of stress may be less adequate than in adults. An additional concern is that a variety of perinatal manipulations, such as the incidental or accidental ingestion of a chemical, may lead to varying degrees of altered morphogenesis or functional development of the kidney. Chemical induced renal anomalies may be of several types, but in typical teratology experiments hydronephrosis may be the most frequent observation. The functional consequences of these renal malformations may be lethal or inconsequential or while an animal may be able to survive and develop normally in the presence of a renal malformation, it is possible that a stressful situation would unmask a functional malformation which could compromise survival. Thus, some renal abnormalities may be subtle enough to go unnoticed without experimental tests. Without such tests it is impossible to evaluate the effect of functional alterations on successful adaptation.  (+info)

Involvement of cytochromes P-450 2E1 and 3A4 in the 5-hydroxylation of salicylate in humans. (2/1030)

Hydroxylation of salicylate into 2,3 and 2,5-dihydroxybenzoic acids (2,3-DHBA and 2,5-DHBA) by human liver microsomal preparations was investigated. Kinetic studies demonstrated that salicylate was 5-hydroxylated with two apparent Km: one high-affinity Km of 606 microM and one low-affinity Km greater than 2 mM. Liver microsomes prepared from 15 human samples catalyzed the formation of 2,5-DHBA at metabolic rate of 21.7 +/- 8.5 pmol/mg/min. The formation of 2, 3-DHBA was not P-450 dependent. Formation of 2,5-DHBA was inhibited by 36 +/- 14% following preincubation of microsomes with diethyldithiocarbamate, a mechanism-based selective inhibitor of P-450 2E1. Furthermore, the efficiency of inhibition was significantly correlated with four catalytic activities specific to P-450 2E1, whereas the residual activity was correlated with three P-450 3A4 catalytic activities. Troleandomycin, a mechanism-based inhibitor selective to P-450 3A4, inhibited by 30 +/- 12% the 5-hydroxylation of salicylate, and this inhibition was significantly correlated with nifedipine oxidation, specific to P-450 3A4. The capability of seven recombinant human P-450s to hydroxylate salicylate demonstrated that P-450 2E1 and 3A4 contributed to 2, 5-DHBA formation in approximately equal proportions. The Km values of recombinant P-450 2E1 and 3A4, 280 and 513 microM, respectively, are in the same range as the high-affinity Km measured with human liver microsomes. The plasmatic metabolic ratio 2,5-DHBA/salicylate, measured 2 h after ingestion of 1 g acetylsalicylate, was increased 3-fold in 12 alcoholic patients at the beginning of their withdrawal period versus 15 control subjects. These results confirm that P-450 2E1, inducible by ethanol, is involved in the 5-hydroxylation of salicylate in humans. Furthermore, this ratio was still increased by 2-fold 1 week after ethanol withdrawal. This finding suggests that P-450 3A4, known to be also inducible by alcoholic beverages, plays an important role in this increase, because P-450 2E1 returned to normal levels in less than 3 days after ethanol withdrawal. Finally, in vivo and in vitro data demonstrated that P-450 2E1 and P-450 3A4, both inducible by alcohols, catalyzed the 5-hydroxylation of salicylate.  (+info)

Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid. (3/1030)

The therapeutic potential of drugs that block the induction of cyclooxygenase-2 has been emphasized. When two 4-trifluoromethyl salicylate derivatives [2-acetoxy-4-trifluoromethyl-benzoic acid (triflusal) and its deacetylated metabolite 2-hydroxy-4-trifluoromethylbenzoic acid (HTB)] were compared with aspirin and sodium salicylate as cyclooxygenase-2 (COX-2) inhibitors, we observed that in bacterial lipopolysaccharide-activated human blood, triflusal, aspirin, and HTB, but not sodium salicylate, inhibited COX-2-mediated prostaglandin E2 (PGE2) production (IC50 = 0.16, 0.18, 0.39, and >10 mM, respectively). However, only triflusal and aspirin inhibited purified COX-2 enzyme. To test this apparent discrepancy, we realized that HTB and triflusal (but neither aspirin nor salicylate) produced a concentration-dependent inhibition of COX-2 protein expression in peripheral human mononuclear cells. This observation was further confirmed in a rat air pouch model in vivo, in which both aspirin and triflusal inhibited PGE2 production (ID50 = 18.9 and 11.4 mg/kg p.o., respectively) but only triflusal-treated animals showed a decrease in COX-2 expression. This different behavior may be, at least in part, due to the ability of HTB and triflusal to block the activation of the transcription factor nuclear factor-kappaB to a higher extent than aspirin and sodium salicylate. Thus, in addition to inhibiting the COX-2 activity at therapeutic concentrations, triflusal is able to block through its metabolite HTB the expression of new enzyme, and hence the resumption of PGE2 synthesis. Triflusal and HTB may exert beneficial effects in processes in which de novo COX-2 expression is involved and, in a broader sense, in pathological situations in which genes under nuclear factor-kappaB control are up-regulated.  (+info)

Growth in the presence of salicylate increases fluoroquinolone resistance in Staphylococcus aureus. (4/1030)

Salicylate and acetylsalicylate slightly increased fluoroquinolone resistance in ciprofloxacin-susceptible and -resistant Staphylococcus aureus. Salicylate allowed a greater number of cells from ciprofloxacin-susceptible and -resistant strains to survive on high fluoroquinolone concentrations. Salicylate also increased the frequency with which a susceptible strain mutated to become more resistant to ciprofloxacin.  (+info)

NahW, a novel, inducible salicylate hydroxylase involved in mineralization of naphthalene by Pseudomonas stutzeri AN10. (5/1030)

Two genes, nahG and nahW, encoding two independent salicylate 1-hydroxylases have been identified in the naphthalene-degrading strain Pseudomonas stutzeri AN10. While nahG resides in the same transcriptional unit as the meta-cleavage pathway genes, forming the naphthalene degradation lower pathway, nahW is situated outside but in close proximity to this transcriptional unit. The nahG and nahW genes of P. stutzeri AN10 are induced and expressed upon incubation with salicylate, and the enzymes that are encoded, NahG and NahW, are involved in naphthalene and salicylate metabolism. Both genes, nahG and nahW, have been cloned in Escherichia coli JM109. The overexpression of these genes yields peptides with apparent molecular masses of 46 kDa (NahG) and 43 kDa (NahW), respectively. Both enzymes exhibit broad substrate specificities and metabolize salicylate, methylsalicylates, and chlorosalicylates. However, the relative rates by which the substituted analogs are transformed differ considerably.  (+info)

4-trifluoromethyl derivatives of salicylate, triflusal and its main metabolite 2-hydroxy-4-trifluoromethylbenzoic acid, are potent inhibitors of nuclear factor kappaB activation. (6/1030)

1. The effect of two derivatives of salicylate, 2-hydroxy-4-trifluoromethylbenzoic acid (HTB) and 2-acetoxy-4-trifluoromethylbenzoic acid (triflusal), on the activation of NF-kappaB elicited by tumour necrosis factor-alpha (TNF-alpha) on human umbilical vein endothelial cells (HUVEC) was tested. 2. The expression of the mRNA of vascular cell adhesion molecule-1 (VCAM-1) was studied as an example of a gene the expression of which is regulated by NF-kappaB. To extend these findings to other systems, the induction of nitric oxide synthase in rat adherent peritoneal macrophages was studied. 3. Both HTB and triflusal were more potent than aspirin or salicylate as inhibitors of the nuclear translocation of NF-kappaB. The calculation of the IC50 values showed approximately 2 mM for HTB, 4 mM for aspirin and >4 mM for salicylate. 4. Comparison of the potency of these compounds on VCAM-1 mRNA expression showed complete inhibition by both triflusal and HTB at a concentration of 4 mM whereas aspirin and salicylate produced only 36-43% inhibition at the same concentration. 5. Inhibition of NF-kappaB activation was also observed in rat peritoneal macrophages stimulated via their receptors for the Fc portion of the antibody molecule with IgG/ovalbumin immune complexes. This was accompanied by a dose-dependent inhibition of nitrite production by the L-arginine pathway via iNOS. IC50 values for this effect were 1.13+/-0.12 mM (triflusal), 1.84+/-0.34 (HTB), 6.08+/-1.53 mM (aspirin) and 9.16+/-1.9 mM (salicylate). 6. These data indicate that the incorporation of a 4-trifluoromethyl group to the salicylate molecule strongly enhances its inhibitory effect on NF-kappaB activation, VCAM-1 mRNA expression and iNOS induction, irrespective of the presence of the acetyl moiety involved in the inhibition of cyclo-oxygenase.  (+info)

Reye's syndrome in the United States from 1981 through 1997. (7/1030)

BACKGROUND: Reye's syndrome is characterized by encephalopathy and fatty degeneration of the liver, usually after influenza or varicella. Beginning in 1980, warnings were issued about the use of salicylates in children with those viral infections because of the risk of Reye's syndrome. METHODS: To describe the pattern of Reye's syndrome in the United States, characteristics of the patients, and risk factors for poor outcomes, we analyzed national surveillance data collected from December 1980 through November 1997. The surveillance system is based on voluntary reporting with the use of a standard case-report form. RESULTS: From December 1980 through November 1997 (surveillance years 1981 through 1997), 1207 cases of Reye's syndrome were reported in patients less than 18 years of age. Among those for whom data on race and sex were available, 93 percent were white and 52 percent were girls. The number of reported cases of Reye's syndrome declined sharply after the association of Reye's syndrome with aspirin was reported. After a peak of 555 cases in children reported in 1980, there have been no more than 36 cases per year since 1987. Antecedent illnesses were reported in 93 percent of the children, and detectable blood salicylate levels in 82 percent. The overall case fatality rate was 31 percent. The case fatality rate was highest in children under five years of age (relative risk, 1.8; 95 percent confidence interval, 1.5 to 2.1) and in those with a serum ammonia level above 45 microg per deciliter (26 micromol per liter) (relative risk, 3.4; 95 percent confidence interval, 1.9 to 6.2). CONCLUSIONS: Since 1980, when the association between Reye's syndrome and the use of aspirin during varicella or influenza-like illness was first reported, there has been a sharp decline in the number of infants and children reported to have Reye's syndrome. Because Reye's syndrome is now very rare, any infant or child suspected of having this disorder should undergo extensive investigation to rule out the treatable inborn metabolic disorders that can mimic Reye's syndrome.  (+info)

Enhancing effects of salicylate on tonic and phasic block of Na+ channels by class 1 antiarrhythmic agents in the ventricular myocytes and the guinea pig papillary muscle. (8/1030)

OBJECTIVE: To study the interaction between salicylate and class 1 antiarrhythmic agents. METHODS: The effects of salicylate on class 1 antiarrhythmic agent-induced tonic and phasic block of the Na+ current (INa) of ventricular myocytes and the upstroke velocity of the action potential (Vmax) of papillary muscles were examined by both the patch clamp technique and conventional microelectrode techniques. RESULTS: Salicylate enhanced quinidine-induced tonic and phasic block of INa at a holding potential of -100 mV but not at a holding potential of -140 mV; this enhancement was accompanied by a shift of the hinfinity curve in the presence of quinidine in a further hyperpolarized direction, although salicylate alone did not affect INa. Salicylate enhanced the tonic and phasic block of Vmax induced by quinidine, aprindine and disopyramide but had little effect on that induced by procainamide or mexiletine; the enhancing effects were related to the liposolubility of the drugs. CONCLUSIONS: Salicylate enhanced tonic and phasic block of Na+ channels induced by class 1 highly liposoluble antiarrhythmic agents. Based on the modulated receptor hypothesis, it is probable that this enhancement was mediated by an increase in the affinity of Na+ channel blockers with high lipid solubility to the inactivated state channels.  (+info)

Bismuth subsalicylate - WikipediaBismuth subsalicylate - Wikipedia
Bismuth subsalicylate, sold under the brand name Pepto-Bismol, is an antacid medication used to treat temporary discomforts of the stomach and gastrointestinal tract, such as diarrhea, indigestion, heartburn and nausea. It is also commonly known as pink bismuth. Bismuth subsalicylate has the empirical chemical formula of C7H5BiO4, and it is a colloidal substance obtained by hydrolysis of bismuth salicylate (Bi(C6H4(OH)CO2)3). The actual structure[clarification needed] is unknown and the formulation is only approximate. As a derivative of salicylic acid, bismuth subsalicylate displays anti-inflammatory and bactericidal action. It also acts as an antacid. There are some adverse effects. It can cause a black tongue and black stools in some users of the drug, when it combines with trace amounts of sulfur in saliva and the colon to form bismuth sulfide. Bismuth sulfide is a highly insoluble black salt, and the discoloration seen is temporary and harmless. Long-term use (greater than 6 weeks) may lead ...
https://en.wikipedia.org/wiki/Bismuth_subsalicylate
2-Trifluoromethylbenzoic acid, 3,5-difluorophenyl ester | C14H7F5O2 - PubChem2-Trifluoromethylbenzoic acid, 3,5-difluorophenyl ester | C14H7F5O2 - PubChem
2-Trifluoromethylbenzoic acid, 3,5-difluorophenyl ester | C14H7F5O2 | CID 530822 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/530822
Who should not take bismuth subsalicylate? | Antacid - SharecareWho should not take bismuth subsalicylate? | Antacid - Sharecare
If you are allergic to any ingredients in bismuth subsalicylate or if you are allergic to salicylate pain relievers, you should not take this medicati
https://www.sharecare.com/health/antacids/who-not-take-bismuth-subsalicylate
A sensitive liquid chromatographic assay for plasma aspirin and salicylate concentrations after low doses of aspirin - UQ eSpace
An original, highly sensitive and specific high performance liquid chromatographic method has been developed for the measurement of aspirin and salicylate in plasma. Minimum concentrations of 10 xg/L (aspirin) and 0.5 mg/L (salicylate) can be measured using 1 ml of plasma. After collection, plasma is first treated with physostigmine sulfate to inhibit enzymatic hydrolysis of aspirin to salicylate. Maximal recovery is achieved using an acid extraction into anhydrous diethyl ether with a subsequent drying-down step in an iced water bath. Aspirin and salicylate are separated by elution with a mixture of methanol, 1-butanol, orthophosphoric acid, and water on a reversed-phase octadecyl silane column at 47°C and detected at 234 nm by ultraviolet absorption. Quantitation is achieved using the peak height ratio of aspirin and salicylate to internal standard (m-anisic acid). The assay has been used for the study of simultaneous aspirin and salicylate pharmacokinetics after a single oral dose of 100 mg ...
https://espace.library.uq.edu.au/view/UQ:393233
Salicylate Sensitivity and Intolerance - New Wrinkles
Anyone can be, or become, sensitive to anything, including salicylates. It happens when people or over exposed or continually exposed; however, in the case of salicylates, it usually happens to people with moderate to severe asthma, and then those sufferers develop chronic rhinosinusitis. It also tends to affect older adults or people who have worsening asthma problems, and, yet, the worsening asthma problems may be related to continual exposure to salicylates. So, its a vicious cycle as your health continues to deteriorate, and you experience more and more health problems.. If you have any of the above symptoms, the best way to determine if salicylates is your problem is to begin by eating a diet low in salicylates, and then slowsly add higher salicylate foods back into your diet. For more information on salicylates in food or how to conduct a test see the How Do I Get More Information?section at the bottom of this article. If you have salicylate problems and remove them from your life, your ...
https://www.newrinkles.com/salicylate-sensitivity-and-intolerance/
Bismuth Subsalicylate (Pepto-Bismol®, Kaopectate®) for Dogs and Cats - PetPlace
Use only if your formulation does NOT contain salicylates. Pepto-Bismol® should not be used in cats since it contains salicylates, the active ingredient in aspirin. Cats are very sensitive to aspirin so it should be avoided. WARNING - PLEASE NOTE THAT THE NEW FORMULATIONS OF KAOPECTATE MAY ALSO HAVE SALICYLATES. Do not use if your formulations lists salicylates as an active ingredient. Any vomiting or diarrhea that persists for more than 24 hours needs your veterinarian's attention. ...
https://www.petplace.com/article/drug-library/drug-library/library/bismuth-subsalicylate-pepto-bismol-kaopectate-for-dogs-and-cats/
Methyl Salicylate Manufacturers, Suppliers & Exporters in IndiaMethyl Salicylate Manufacturers, Suppliers & Exporters in India
Search Indian Methyl Salicylate Manufacturers and Suppliers Details - Contact to Methyl Salicylate Exporters in India, Methyl Salicylate Wholesalers, Methyl Salicylate Distributors and Traders from India.
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Hexyl salicylate - Registration Dossier - ECHAHexyl salicylate - Registration Dossier - ECHA
Toxicokinetics The 17 salicylate substances assessed in the RIFM review indicate consistent metabolism by hydrolysis to form salicylic acid and the alcohol of the corresponding side chain. This pattern of metabolism is consistent with information on other esters which are hydrolysedin vivoby carboxylesterases or esterases, especially the A-esterases. In vivo metabolic data are available for methyl salicylate and one human metabolism study is available on phenyl salicylate. Carboxylesterases show extensive tissue distribution with respect to hydrolysis of methyl salicylate. In vitro studies demonstrate greatest activity in the liver, but also extensive activity in the intestines, kidney, pancreas and spleen. Both the liver and intestines can contribute to the pre-systemic hydrolysis of salicylates. Oral consumption of 0.42 mL methyl salicylate by human volunteers resulted in the rapid appearance of salicylic acid in the plasma. At 15 and 90 minutes post administration, salicylic acid ...
https://echa.europa.eu/et/registration-dossier/-/registered-dossier/14766/7/2/1
Plus itPlus it
Salsalate is a prodrug of salicylate that lowers blood glucose in patients with type 2 diabetes (T2D) and reduces non-alcoholic fatty liver disease (NAFLD) in animal models; however, the mechanism mediating these effects is unclear. Salicylate directly activates AMP-activated protein kinase (AMPK) via the β1 subunit but whether salsalate requires AMPK β1 to improve T2D and NAFLD has not been examined. Therefore, wild-type (WT) and AMPK β1 knockout mice (AMPK β1KO) were treated with a salsalate dose resulting in clinically relevant serum salicylate concentrations (∼1 mM). Salsalate treatment increased oxygen consumption, lowered fasting glucose, improved glucose tolerance and led to an ∼55% reduction in liver lipid content; effects observed in both WT and AMPK β1KO mice. To explain these AMPK-independent effects, it was found that salicylate increases oligomycin-insensitive respiration (state 4o) and directly increases mitochondrial proton conductance at clinical concentrations. This ...
http://diabetes.diabetesjournals.org/content/early/2016/08/19/db16-0564
Bismuth Subsalicylate | Pet Poison Control
It is important to note that cats are more sensitive to toxicity with salicylates and should never be given this medication.. Signs and symptoms of toxicity: vomiting, diarrhea, melena (dark, tarry stool), abdominal pain, pale gums, altered mental status, difficulty breathing, and dehydration. While some signs may appear within several hours of ingestion, it may take several days for other signs to appear.. Toxic consumption: Do not exceed dosing recommendations from your veterinarian. Report all incidents of accidental ingestion immediately.. References ...
http://www.petpoisoncontrol.com/portfolio/bismuth-subsalicylate/
3-Trifluoromethylbenzoic acid, hex-4-yn-3-yl ester3-Trifluoromethylbenzoic acid, hex-4-yn-3-yl ester
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
https://webbook.nist.gov/cgi/inchi/InChI%3D1S/C14H13F3O2/c1-3-6-12
5-Fluoro-3-trifluoromethylbenzoic acid, nonyl ester5-Fluoro-3-trifluoromethylbenzoic acid, nonyl ester
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
https://webbook.nist.gov/cgi/inchi?ID=U338901&Units=CAL
Beaumont Laboratory - Lab Test Details
The salicylate assay aids in the diagnosis and treatment of salicylate overdose and in monitoring salicylate levels to insure appropriate therapy. Salicylates are a group of compounds used as analgesics, antipyretics and anti-inflammatory agents. Acetylsalicylic acid (aspirin) is the most commonly used salicylate. Salicylates are readily available over-the-counter and most salicylate therapy is the result of patient self-medication. For this reason, salicylates are often seen in overdose cases. Salicylate poisoning is seldom fatal, but causes side effects ranging from nausea, vomiting and tinnitus to fever, lethargy and coma. Prompt recognition and management are necessary to avoid serious consequences. ...
http://beaumontlaboratory.com/test-lab-directory/lab-test-details/?testid=507
Bismuth by Jamp Pharma - Uses, Side Effects, Interactions - Canoe.com
Bismuth by Jamp Pharma: Bismuth subsalicylate belongs to a class of medications called antacids and adsorbents. It is used to help relieve heartburn, indigestion, upset stomach, nausea, and diarrhea. How bismuth subsalicylate works is not completely understood, but it is thought to work by coating the stomach and intestines (protecting them from stomach acid), by reducing inflammation in the stomach, and by killing certain bacteria.
https://chealth.canoe.com/drug/getdrug/bismuth-by-jamp-pharma
Hexyl salicylate - Registration Dossier - ECHAHexyl salicylate - Registration Dossier - ECHA
This data point has been waived for hexyl salicylate on the grounds that exposure is not expected to occur. A study by Simonich et al (2000) demonstrated that hexyl salicylate removal is highly efficient during wastewater treatment (98.7 - 99.8% following primary and secondary removal, depending on the type of treatment), and consequently exposure to soil (i.e. via spreading of sludge) will be negligible. Furthermore, hexyl salicylate is readily biodegradable and therefore non-persistent in the environment. Resulting degradation products show low log Kow values and low anticipated ecotoxicity, and the equilibrium partitioning method is therefore considered sufficiently conservative for risk assessment. Under these circumstances, data for the effects of hexyl salicylate on terrestrial arthropods are considered unnecessary. ...
https://echa.europa.eu/registration-dossier/-/registered-dossier/14766/6/4/3
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Salicylate poisoning - WikipediaSalicylate poisoning - Wikipedia
Salicylate poisoning, also known as aspirin poisoning, is the acute or chronic poisoning with a salicylate such as aspirin. The classic symptoms are ringing in the ears, nausea, abdominal pain, and a fast breathing rate. Early on these may be subtle while larger doses may result in fever. Complications can include swelling of the brain or lungs, seizures, low blood sugar, or cardiac arrest. While usually due to aspirin, other possible causes include oil of wintergreen and bismuth subsalicylate. Excess doses can be either on purpose or accidental. Small amounts of oil of wintergreen can be toxic. Diagnosis is generally based on repeated blood tests measuring aspirin levels and blood gases. While a type of graph has been created to try to assist with diagnosis, its general use is not recommended. In overdose maximum blood levels may not occur for more than 12 hours. Efforts to prevent poisoning include child-resistant packaging and a lower number of pills per package. Treatment may include ...
https://en.wikipedia.org/wiki/Salicylate_poisoning
The impact of salsalate treatment on serum levels of advanced glycatio by Joshua I Barzilay, Kathleen A. Jablonski et al.The impact of salsalate treatment on serum levels of advanced glycatio by Joshua I Barzilay, Kathleen A. Jablonski et al.
OBJECTIVE Salsalate is a nonacetylated salicylate that lowers glucose levels in people with type 2 diabetes (T2D). Here we examined whether salsalate also lowered serum-protein-bound levels of early and advanced glycation end products (AGEs) that have been implicated in diabetic vascular complications. RESEARCH DESIGN AND METHODS Participants were from the Targeting Inflammation Using Salsalate for Type 2 Diabetes (TINSAL-T2D) study, which examined the impact of salsalate treatment on hemoglobin A1c (HbA1c) and a wide variety of other parameters. One hundred eighteen participants received salsalate, 3.5 g/day for 48 weeks, and 109 received placebo. Early glycation product levels (HbA1c and fructoselysine [measured as furosine]) and AGE levels (glyoxal and methylglyoxal hydroimidazolones [G-(1)H, MG-(1)H], carboxymethyllysine [CML], carboxyethyllysine [CEL], pentosidine) were measured in patient serum samples. RESULTS Forty-eight weeks of salsalate treatment lowered levels of HbA1c and serum furosine (P
https://hsrc.himmelfarb.gwu.edu/biostatscenter_facpubs/185/
Salicylate protects hearing and kidney function from cisplatin toxicity without compromising its oncolytic action<...Salicylate protects hearing and kidney function from cisplatin toxicity without compromising its oncolytic action<...
TY - JOUR. T1 - Salicylate protects hearing and kidney function from cisplatin toxicity without compromising its oncolytic action. AU - Li, Geming. AU - Sha, Su Hua. AU - Zotova, Elena. AU - Arezzo, Joseph. AU - Van De Water, Thomas R.. AU - Schacht, Jochen. PY - 2002/1/1. Y1 - 2002/1/1. N2 - Salicylate has recently been demonstrated to protect against the auditory and vestibular side effects of aminoglycoside antibiotics. Similarities in the toxic mechanisms suggest salicylate as a treatment strategy to prevent the ototoxic side effects of cisplatin (CDDP). We first tested protection of the inner ear in Wistar rats receiving a single infusion of 16 mg CDDP/kg body weight with or without treatment with 100 mg/kg salicylate (bid) for 5 days beginning one day before the CDDP infusion. Cisplatin induced a threshold shift of more than 30 dB (at 14 kHz; measured by auditory evoked brain stem response) that was significantly reduced by salicylate. We then examined the protective potential of ...
https://einstein.pure.elsevier.com/en/publications/salicylate-protects-hearing-and-kidney-function-from-cisplatin-to-2
2-ethylhexyl salicylate - Registration Dossier - ECHA2-ethylhexyl salicylate - Registration Dossier - ECHA
It is concluded that the absorption of 2-ethylhexyl salicylate via the dermal route is very low (3%), while it is well absorbed via the oral route (100% absorption assumed). Following absorption, 2-ethylhexyl salicylate is metabolized to salicylic acid and 2-ethylhexanol rapidly. Salicylic acid is mainly excreted by renal excretion as an unchanged chemical entity or after conjugation with glycine as salicyluric acid. 2-Ethylhexanol is metabolized following metabolic pathways of alcohols with its degradation products mainly excreted in respiratory CO2, via faeces and urine. No accumulation in the body is expected due to efficient metabolic pathways and formation of soluble degradation products (salicylic acid and 2-ethylhexanol) with established elimination routes. Due to low vapor pressure (1.8E-4hPa at 20 °C, Symrise) and high boiling point (, 300 °C, Intertek ASG), the inhalation route is not considered to be a relevant exposure route to human for 2-ethylhexyl salicylate. ...
https://www.echa.europa.eu/en/web/guest/registration-dossier/-/registered-dossier/14203/7/2/1
Salicylates (Aspirin) | Lab Tests OnlineSalicylates (Aspirin) | Lab Tests Online
Salicylates are a group of drugs, including aspirin, that are used to relieve pain and inflammation and to reduce fever. Salicylate testing may be used to detect a high level of salicylate in the blood and help diagnose an overdose (salicylate poisoning).
https://labtestsonline.org/tests/salicylates-aspirin
methyl salicylate topicalmethyl salicylate topical
Methyl salicylate topical (for the skin) is used for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising, or backaches. Methyl salicylate topical may also be used for purposes not listed in this medication guide.
https://www.johnstonhealth.org/fitness-health/library/document-viewer/?id=d03668a1
Methyl Salicylate pharmaceutical drugs and health productsMethyl Salicylate pharmaceutical drugs and health products
Methyl Salicylate containing medications, Methyl Salicylate indications and usages ATC and ICD codes, combinations with other active ingredients and trade names information from Drugs-about.com
http://drugs-about.com/ing/methyl-salicylate.html
Tea against ACT: David against Goliath | MalariaWorldTea against ACT: David against Goliath | MalariaWorld
The interference of analgesics with ACTs (Coartem, Corsucam…) has barely been studied in clinical trials.. Aspirin (acetylsalicylic acid) is sold over the counter in Africa and appears to be the first line treatment when children or adults have fever. Chronic salicylate poisoning by overdosis is common. Many children brought to a hospital in Africa have a high load of salicylic acid in their blood. Paracetamol is also of common use.. In all children admitted to Kilifi District Hospital between July and September, 1994, who had a positive blood film for Plasmodium falciparum, and one or more of coma, prostration, or respiratory distress salicylate concentrations were measured. (English M1, et al., Lancet. 1996 347(9017):1736-7). Data were available for 143 children with initial primary diagnoses of severe malaria. 129 had detectable (,l mg/dL) salicylate. Six of these had salicylate concentrations of 20 mg/dL or higher. All six had neurological impairment and metabolic acidosis and four were, ...
https://malariaworld.org/comment/1484
Full text of Medical Jurisprudence And ToxicologyFull text of Medical Jurisprudence And Toxicology
SALICYLIC ACID 477 Methyl Salicylate. This is also known as artificial oil of wintergreen, and is obtained by the interaction of methyl alcohol and salicylic acid. It is a colourless liquid, having a characteristic, aromatic odour and a sweetish, warm, aromatic taste. It is slightly soluble in water, and freely soluble in alcohol, ether, chloroform, glacial acetic acid or carbon bisulphide. Methyl salicylate is taken accidentally, suicidally or to procure abortion, and causes symptoms of acute gastro-intestinal irritation resembling those of poisoning by salicylic acid, followed occasionally by death. About an ounce of methyl salicylate proved fatal to an adult woman in 15 hours42 and a dose of 50 ml. of methyl salicylate caused the death of a middle aged woman hi about 11 hours.43 Doses of 10 cc. to 12 cc. of methyl salicylate have killed children.44 On the other hand, a child, aged 2 years, recovered after swallowing an ounce.45 The treatment consists in the washing out of the stomach and ...
http://www.archive.org/stream/MedicalJurisprudenceAndToxicology/TXT/00000488.txt
Choline salicylate + cetalkonium chloride : usage, side effects, expert advice and choline salicylate + cetalkonium chloride...Choline salicylate + cetalkonium chloride : usage, side effects, expert advice and choline salicylate + cetalkonium chloride...
Choline salicylate + cetalkonium chloride is used in the treatment of .get complete information about choline salicylate + cetalkonium chloride including usage, side effects, drug interaction, expert advice along with medicines associated with choline salicylate + cetalkonium chloride at 1mg.com
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What does salicylate mean?What does salicylate mean?
Definition of salicylate in the Definitions.net dictionary. Meaning of salicylate. What does salicylate mean? Information and translations of salicylate in the most comprehensive dictionary definitions resource on the web.
http://www.definitions.net/definition/salicylate
Decongestant And Analgesic Combinations (Oral Route) Side Effects - Mayo ClinicDecongestant And Analgesic Combinations (Oral Route) Side Effects - Mayo Clinic
Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are taking this medicine.. Check the label of all over-the-counter (OTC), nonprescription, and prescription medicines you now take. If any of them contain acetaminophen, aspirin, other salicylates such as bismuth subsalicylate (e.g., Pepto Bismol) or magnesium salicylate (e.g., Nuprin Backache Caplets), or salicylic acid (present in some shampoos and skin products), check with your health care professional. Using any of them together with this medicine may cause an overdose.. Do not drink alcoholic beverages while taking this medicine. Stomach problems may be more likely to occur if you drink alcoholic beverages while you are taking aspirin or ibuprofen. Also, liver damage may be more likely to occur if you drink large amounts of alcoholic beverages while you are taking acetaminophen.. If you think that you or anyone else may have taken an overdose of this ...
https://www.mayoclinic.org/drugs-supplements/decongestant-and-analgesic-combinations-oral-route/side-effects/DRG-20070131?p=1
Pink Bismuth w/Protective Coating 30 chewable tablets - Daly Drug Pharmacy
Good Neighbor Pharmacy Anti-diarrheal Made with protective coating 102 mg Salicylate/tablet 262 mg Bismuth subsalicylate/tablets 30 chewable tablets/box
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Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults | American College of GastroenterologyDiagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults | American College of Gastroenterology
Summary of evidence. Traveler setting: Prevention of TD is challenging because of the ubiquitous exposures to individuals through contaminated food, water, and generally unhygienic conditions among much of the developing world. Travelers are frequently counseled on preventive risk behaviors, but despite a travelers best attention to such recommendations, evidence is lacking that such precautions have any protective effect (188). Although vaccines for many of the agents commonly associated with TD are under development, these are considered a long-term solution and might likely suffer from the lack of utilization as has been seen with most travel-associated vaccines (202, 203, 204,205, 206). Alternative primary prevention strategies such as BSS, probiotics, and antibiotics have been evaluated and are considered here.. Bismuth subsalicylate. BSS has been shown in several studies to reduce the frequency of TD when used during period of risk for 3 weeks (207, 208, 209). While the salicylate portion ...
http://gi.org/guideline/diagnosis-treatment-and-prevention-of-acute-diarrheal-infections-in-adults/
Bismuth | WSC RocketryBismuth | WSC Rocketry
At first glance, bismuth doesnt seem to be particularly extraordinary. Element number 83 is probably most likely encountered in the compound bismuth subsalicylate (C7H5BiO4), used in gastro-intestinal remedies such as Pepto Bismol. The pure metal is also gaining popularity as a more environmentally friendly (and much more expensive) alternative to lead in hunting ammunition. In…
https://wscrocketry.com/scientific-miscellany/element-collection/bismuth/
Haemodialysis Management For Salicylate Intoxication 2019 • Kidney Treatment
Salicylate poisoning is a potentially toxic level of salicylate in the blood which may be acute or chronic. Hemodialysis. For chronic salicylate toxicity,
https://kidneytreatment.site/haemodialysis-management-for-salicylate-intoxication
Salsalate - wikidocSalsalate - wikidoc
Salsalate is insoluble in acid gastric fluids (,0.1 mg/ml at pH 1.0), but readily soluble in the small intestine where it is partially hydrolyzed to two molecules of salicylic acid. A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis in the body: its half-life is about one hour. About 13% is excreted through the kidneys as a glucuronide conjugate of the parent compound, the remainder as salicylic acid and its metabolites. Thus, the amount of salicylic acid available from salsalate is about 15% less than from aspirin, when the two drugs are administered on a salicylic acid molar equivalent basis (3.6 g salsalate/5 g aspirin ...
http://wikidoc.org/index.php/Salsalate
Role of oxidative stress in age-associated mild cognitive impairment and Alzheimers disease :: University of Southern...
Continuous decline in cognitive performance accompanies the natural aging process in humans, and multiple studies in both humans and animal models have indicated that this decrease in cognitive function is associated with an age-related increase in oxidative stress. Treating aging mammals with exogenous free radical scavengers has generally been shown to attenuate age-related cognitive decline and oxidative stress. I assessed the effectiveness of the superoxide dismutase/catalase mimetics EUK-189 and EUK-207 on age-related decline in cognitive function and increase in oxidative stress. C57/BL6 mice received continuous treatment via osmotic minipumps with either EUK-189 or EUK-207 for 6 months starting at 17 months of age. At the end of treatment, markers for oxidative stress were evaluated by analyzing levels of free radicals, lipid peroxidation and oxidized nucleic acids in brain tissue. In addition, cognitive performance was assessed after 3 and 6 months of treatment with fear conditioning. ...
http://digitallibrary.usc.edu/cdm/ref/collection/p15799coll127/id/457660
EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced...EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced...
These results indicate that pretreatment of rats with the synthetic catalytic scavenger of ROS, EUK-134, prevents oxidative stress and produces a significant degree of protection against the pathological manifestations of KA-induced seizure activity in hippocampus and piriform cortex. Although numerous studies have suggested that ROS are critically involved in excitotoxicity (see refs. 5, 30, and 31 for reviews), very few studies have demonstrated convincingly, in an in vivo excitotoxic model, a causal relationship between increased production of ROS and neuronal damage (7, 32). A clear demonstration of the crucial role of ROS in excitotoxicity should include: (i) evidence for increased production of ROS specifically in neuronal populations at risk with excitotoxicity before overt signs of neuronal damage and (ii) evidence that manipulations aimed at preventing ROS accumulation reduce neuronal damage without interfering with excitatory amino acid receptor functions. The former has been difficult ...
http://www.pnas.org/content/96/17/9897.full
Buy Methyl Salicylate Online | 100ml $16.00 - Lab AlleyBuy Methyl Salicylate Online | 100ml $16.00 - Lab Alley
Buy High Purity Methyl Salicylate | Medical Grade For Sale Online In USA | Oil of Wintergreen | For Topical Pain Relief Ointments | 100ml $16.00 | Methyl Ester Of Salicylic Acid | Formula C8H8O3 | Synthetic Form | CAS 119-36-8 | Weight 152.15 | Bulk Supplier & Distributor
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TriflusalTriflusal
Triflusal Triflusal Systematic (IUPAC) name 2-acetyloxy-4-(trifluoromethyl)benzoic acid Identifiers CAS number  ? ATC code B01AC18 PubChem 9458 Chemical
https://www.chemeurope.com/en/encyclopedia/Triflusal.html
Triflusal Posttreatment Inhibits Glial Nuclear Factor-κB, Downregulates the Glial Response, and Is Neuroprotective in an...Triflusal Posttreatment Inhibits Glial Nuclear Factor-κB, Downregulates the Glial Response, and Is Neuroprotective in an...
After an excitotoxic lesion in the postnatal cortex, glial NF-κB is consistently activated at 10 hours after injury, showing its peak at day 1.4 Therefore, when triflusal is orally administered 8 hours after the NMDA injection, it preferentially targets NF-κB induced in glial cells, as the inducible neuronal NF-κB is starting to decrease when triflusal reaches the brain. Glial NF-κB is probably induced by injury-related signals that occur in the degenerating area. They may include reactive oxygen species, produced in excitotoxically damaged cells,44 and the proinflammatory cytokines interleukin-1β and tumor necrosis factor-α, which are expressed by neurons and glial cells in this excitotoxic lesion model, showing a peak of expression at 10 hours after injury.45 On activation, NF-κB translocates to the cell nucleus and modulates the expression of several genes implicated in the development of the glial and inflammatory responses. Target genes containing a NF-κB-binding site include the ...
http://stroke.ahajournals.org/content/32/10/2394
Iodex With Methyl Salicylate - 1 OZ - MedshopexpressIodex With Methyl Salicylate - 1 OZ - Medshopexpress
Temporarily relieves minor aches and pains. IODEX with methyl salicylate will relieve local congestion moderating the symptoms: local aches and pains,...
https://www.medshopexpress.com/iodex-with-methyl-salicylate-1-oz
Targeting Inflammation Using Salsalate in CardioVascular Disease - Full Text View - ClinicalTrials.govTargeting Inflammation Using Salsalate in CardioVascular Disease - Full Text View - ClinicalTrials.gov
The hypothesis is that western lifestyle, with sedentary behaviors and caloric excess promote a chronic, subacute inflammatory state that participates in the development and progression of atherosclerosis. We will evaluate the effects of targeting inflammation using the anti-inflammatory drug salsalate, compared to placebo, on coronary artery plaque volume assessed by multi-detector computed tomographic angiography (MDCTA). The TINSAL-CVD study is a randomized, double-masked, placebo-controlled, 2 arm, clinical trial.. The purpose of the study is to compare the effect of salsalate or placebo on sub-acute inflammation and coronary plaque, in people with cardiovascular disease. Participants are randomized to active intervention (salsalate) or placebo interventions for a period of 30 months. The primary endpoint is change in plaque volume in the coronary arteries assessed by MDCTA from baseline to 30 months. ...
https://clinicaltrials.gov/show/NCT00624923
Targeting Inflammation Using Salsalate in CardioVascular Disease - Tabular View - ClinicalTrials.govTargeting Inflammation Using Salsalate in CardioVascular Disease - Tabular View - ClinicalTrials.gov
The hypothesis is that western lifestyle, with sedentary behaviors and caloric excess promote a chronic, subacute inflammatory state that participates in the development and progression of atherosclerosis. We will evaluate the effects of targeting inflammation using the anti-inflammatory drug salsalate, compared to placebo, on coronary artery plaque volume assessed by multi-detector computed tomographic angiography (MDCTA). The TINSAL-CVD study is a randomized, double-masked, placebo-controlled, 2 arm, clinical trial.. The purpose of the study is to compare the effect of salsalate or placebo on sub-acute inflammation and coronary plaque, in people with cardiovascular disease. Participants are randomized to active intervention (salsalate) or placebo interventions for a period of 30 months. The primary endpoint is change in plaque volume in the coronary arteries assessed by MDCTA from baseline to 30 months. ...
https://clinicaltrials.gov/ct2/show/record/NCT00624923?show_rss=Y&sel_rss=mod14
Bismuth Subsalicylate supplier distributor- CAS 14882-18-9Bismuth Subsalicylate supplier distributor- CAS 14882-18-9
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bismuth subsalicylate 14882-18-9 safety info, bismuth subsalicylate chemical safety search, Chemical bismuth subsalicylate safety technical specifications ect.
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bismuth subsalicylate - WellSpan Health Librarybismuth subsalicylate - WellSpan Health Library
Bismuth subsalicylate is an antacid and anti-diarrhea medication. Bismuth subsalicylate is used to treat diarrhea, nausea, heartburn, indigestion, and upset stomach. Bismuth subsalicylate may also be used for purposes not listed in this medication guide.
https://www.wellspan.org/health-library/Document.aspx?id=d01026a1
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Bismuth subsalicylate: Uses, Interactions, Mechanism of Action | DrugBank OnlineBismuth subsalicylate: Uses, Interactions, Mechanism of Action | DrugBank Online
Bismuth subsalicylate is an antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
https://go.drugbank.com/drugs/DB01294
NDC 70000-0439 Leader Stomach Relief Bismuth SubsalicylateNDC 70000-0439 Leader Stomach Relief Bismuth Subsalicylate
Leader Stomach Relief with NDC 70000-0439 is a a human over the counter drug product labeled by Cardinal Health. The generic name of Leader Stomach Relief is bismuth subsalicylate.
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NDC 55319-736 Stomach Relief Bismuth SubsalicylateNDC 55319-736 Stomach Relief Bismuth Subsalicylate
Stomach Relief with NDC 55319-736 is a a human over the counter drug product labeled by Family Dollar (family Wellness). The generic name of Stomach Relief is bismuth subsalicylate.
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Bismuth Subsalicylate Effects
The therapeutic effect of bismuth subsalicylate BSS Pepto-Bismol in Clostridium difficile colitis was studied in golden Syrian hamsters. C. difficile was fed to the hamsters by orogastric intubation 2-3 days after their arrival. Clindamycin 1.5 mg per animal was given intraperitoneally 4 days l
https://www.123binz.de/498/bismuth_subsalicylate_effects.html
Family Medicine Update: Bismuth subsalicylate in Travelers Diarrhea
Bismuth subsalicylate can be useful in the prevention and treatment of travelers diarrhea. Antibiotic prophylaxis is not routinely recommended. Treatment is typically with a fluoroquinolone or azithromycin. One recommended fluid replacement is: 1L of water with 1/2 tsp salt, 1/2 tsp baking soda, and 4 tbsp sugar ...
http://www.familymedicineupdate.com/2014/04/bismuth-subsalicylate-in-travelers.html
Effects of bismuth subsalicylate and encapsulated calcium ammonium nitrate on ruminal fermentation of beef cattle<...
TY - JOUR. T1 - Effects of bismuth subsalicylate and encapsulated calcium ammonium nitrate on ruminal fermentation of beef cattle. AU - Henry, Darren D.. AU - Ciriaco, Francine M.. AU - Araujo, Rafael C.. AU - Fontes, Pedro L.P.. AU - Oosthuizen, Nicola. AU - Mejia-Turcios, Sebastian E.. AU - Garcia-Ascolani, Mariana E.. AU - Rostoll-Cangiano, Lautaro. AU - Schulmeister, Tessa M.. AU - Dubeux, Jose C.B.. AU - Cliff Lamb, G.. AU - DiLorenzo, Nicolas. N1 - Funding Information: This material is based upon work that is supported by the Foundational Program (Grant no. 2016-08402) and the Agriculture and Food Research Initiative-Food, Natural Resources and Human Sciences Education and Literacy Initiative (Award no. 2017-67011-26063) from the United States Department of Agriculture National Institute of Food and Agriculture. We wish to thank Quality Liquid Feeds for donating the molasses used in this experiment, Westway Feed Products for donating the urea used in this experiment, and GRASP Ind. & Com. ...
https://scholars.ttu.edu/en/publications/effects-of-bismuth-subsalicylate-and-encapsulated-calcium-ammoniu-2
Bismuth Subsalicylate Suspension - FDA prescribing information, side effects and usesBismuth Subsalicylate Suspension - FDA prescribing information, side effects and uses
Bismuth Subsalicylate Suspension official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.
https://www.drugs.com/pro/bismuth-subsalicylate-suspension.html
Bismuth Subsalicylate (Kaopectate, Pepto-Bismol) Nursing Pharmacology Considerations | NURSING.comBismuth Subsalicylate (Kaopectate, Pepto-Bismol) Nursing Pharmacology Considerations | NURSING.com
Learn everything you need to know about bismuth subsalicylate (kaopectate) and its nursing considerations incluing classification and common side effects
https://nursing.com/blog/bismuth-subsalicylate-kaopectate-pepto-bismol-nursing-pharmacology-considerations/
Bismuth subsalicylate and Diamox Drug Interactions - Drugs.comBismuth subsalicylate and Diamox Drug Interactions - Drugs.com
A Major Drug Interaction exists between bismuth subsalicylate and Diamox. View detailed information regarding this drug interaction.
https://www.drugs.com/drug-interactions/bismuth-subsalicylate-with-diamox-391-0-86-3180.html
Frontiers | Potassium Channel Activator Attenuates Salicylate-Induced Cochlear Hearing Loss Potentially Ameliorating Tinnitus |...Frontiers | Potassium Channel Activator Attenuates Salicylate-Induced Cochlear Hearing Loss Potentially Ameliorating Tinnitus |...
High dose sodium salicylate causes moderate, reversible hearing loss and tinnitus. Salicylate-induced hearing loss is believed to arise from a reduction in the electromotile response of outer hair cells (OHCs) and/or reduction of KCNQ4 potassium currents in OHCs which decreases the driving force for the transduction current. Therefore, enhancing OHC potassium currents could potentially prevent salicylate-induced temporary hearing loss. In this study, we tested whether opening voltage-gated potassium channels using ICA-105665, a novel small molecule that opens KCNQ2/3 and KCNQ3/5 channels, can reduce salicylate-induced hearing loss. We found that systemic application of ICA-105665 at 10 mg/kg prevented the salicylate-induced amplitude reduction and threshold shift in the compound action potentials recorded at the round window of the cochlea. ICA-105665 also prevented the salicylate-induced reduction of distortion products of otoacoustic emission (DPOAE). These results suggest that ICA-105665
https://www.frontiersin.org/articles/10.3389/fneur.2015.00077/full
Thiosalicylic acid sodium salt - Alfa ChemistryThiosalicylic acid sodium salt - Alfa Chemistry
Thiosalicylic acid sodium salt/AFI134236 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
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Perfume Shrine: Perfume Ingredient: Salicylates ~Smell, Role and FunctionPerfume Shrine: Perfume Ingredient: Salicylates ~Smell, Role and Function
Benzyl Salicylate (benzyl ortho hydroxy benzoate) is an almost colourless liquid that has a mild balsamic, sweetly floral note possessing excellent blending capabilities. Often used ~like foundation is for make-up~ as a base for heavy florals such as ylang, gardenia, jasmine, lily etc. It is also used in functional products such as soap, shampoo and fabric softener. Along with Methyl Salicylate, salicylates turn the most banal floral composition into a real perfume, with majestic weight and sweep divulges Luca Turin. However some people are anosmic to it, including some perfumers. Guy Robert could not smell benzyl salicylate at all, but could instantly recognize its presence in perfume: I recognize it as if it were a friend seen from behind in a crowd, by the cut of his shoulders. Indeed in the words of nose Bernand Chant it produces a diffusing, blooming effect very pleasing to the public. Many orchid fragrances are built on salicylates, while the mysterious emerald glow of the vintage Je ...
https://perfumeshrine.blogspot.com/2009/09/perfume-ingredient-salicylates-smell.html
Sensitivity of Hypothalamic Sites to Salicylate and Prostaglandin by Linda K. Vaughn, W. L. Veale et al.Sensitivity of Hypothalamic Sites to Salicylate and Prostaglandin by Linda K. Vaughn, W. L. Veale et al.
This study was designed to determine the dose of salicylate necessary to produce substantial antipyresis, and to determine the relationship between the response to salicylate and prostaglandin infused into the same region of the preoptic area of the rabbit. The effect of preoptic infusions of three doses of sodium salicylate, or a control solution, on the fever produced by an intravenous injection of endogenous pyrogen was measured. The pyrogenic response to prostaglandin E1 injected into the same preoptic sites in the same rabbits was also monitored. The results showed that the 50 μg/μL per hour dose of salicylate did not produce significant antipyresis but that the 100 and 200 μg/μL per hour doses did. The results also showed a significant correlation between the magnitude of fever produced by prostaglandin E1 and the magnitude of antipyresis produced by sodium salicylate at a particular site. Those sites at which infusion of salicylate produced the most effective antipyresis were also the ones at
http://epublications.marquette.edu/biomedsci_fac/61/
How to Salicylate determination with visual colorimetry « Science Experiments :: WonderHowToHow to Salicylate determination with visual colorimetry « Science Experiments :: WonderHowTo
If youre interested in forensic toxicology and are trying to determine the presence of salicylate by using a visual colorimetry, then look no further. This indepth and compelling video takes you into world of salicylate determination. Salicylate determination with visual colorimetry, Part I Using iron(III) nitrate to determine salicylate concentration in standardized salicylate solutions and urine. You can actually use any iron(III) salt, such as ferric chloride, ferric ammonium sulfate, and so on. Concentration is not critical
https://science.wonderhowto.com/how-to/salicylate-determination-with-visual-colorimetry-361273/
Different vitamins natural sources normally found antihemophilic factor phenylephrine pramoxine topicalDifferent vitamins natural sources normally found antihemophilic factor phenylephrine pramoxine topical
3. Helidac (Bismuth Subsalicylate/Metronidazole/Tcn) Bismuth subsalicylate is a mild antibiotic. Helitene (Collagen Topical) Helixate FS (Antihemophilic Factor) Antihemophilic factor is a naturally occurring protein in the blood that helps blood to clot
https://www.medslook.com/h04.htm
Bismuth Subsalicylate oral liquid - Gundersen Health System - La Crosse, Wisconsin
Take this medicine by mouth. Follow the directions on the label. Shake well before using. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Do not take your medicine more often than directed.. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this medicine may be used in children as young as 12 years for selected conditions, precautions do apply.. ...
http://healthinfo.gundersenhealth.org/RelatedItems/121,228
Bismuth Subsalicylate tablets | Northwestern MedicineBismuth Subsalicylate tablets | Northwestern Medicine
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Do not treat diarrhea for more than 2 days without talking to your doctor or health care professional. Call your doctor or health care professional as soon as you can if you get a fever, or nausea and vomiting. These could be symptoms of a more serious illness.. Drink plenty of clear fluids to help prevent dehydration caused by diarrhea.. ...
https://encyclopedia.nm.org/RelatedItems/121,227
Bismuth Subsalicylate - Guardian and I.D.A.Bismuth Subsalicylate - Guardian and I.D.A.
This medication is typically used 4 times a day. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Generally, it is used only as needed. If you forget a dose, take it as soon as you remember -- unless it is almost time for your next dose. In that case, skip the missed dose. Do not double the next dose to catch up. This medication may be taken with or without food. It is recommended to drink plenty of water while using this medication. ...
https://www.guardian-ida-pharmacies.ca/en/article/bismuth-subsalicylate-55cec
Bismuth Subsalicylate tablets - Gundersen Health System - La Crosse, Wisconsin
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Do not treat diarrhea for more than 2 days without talking to your doctor or health care professional. Call your doctor or health care professional as soon as you can if you get a fever, or nausea and vomiting. These could be symptoms of a more serious illness.. Drink plenty of clear fluids to help prevent dehydration caused by diarrhea.. ...
http://healthinfo.gundersenhealth.org/RelatedItems/121,227
Krames Online - Bismuth Subsalicylate tabletsKrames Online - Bismuth Subsalicylate tablets
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Do not treat diarrhea for more than 2 days without talking to your doctor or health care professional. Call your doctor or health care professional as soon as you can if you get a fever, or nausea and vomiting. These could be symptoms of a more serious illness.. Drink plenty of clear fluids to help prevent dehydration caused by diarrhea.. ...
http://gallagherorthopedics.kramesonline.com/Medications/121,S,227
Bismuth Subsalicylate: Pediatric Medication | Memorial Sloan Kettering Cancer CenterBismuth Subsalicylate: Pediatric Medication | Memorial Sloan Kettering Cancer Center
This information from Lexicomp® explains what you need to know about this medication, including what its used for, how to take it, its side effects, and when to call your healthcare provider.
https://www.mskcc.org/cancer-care/patient-education/bismuth-subsalicylate
Drug Notes - Bismuth subsalicylate (By mouth)Drug Notes - Bismuth subsalicylate (By mouth)
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites ...
http://nch.adam.com/content.aspx?productid=45&pid=45&gid=4857
Drugs - bismuth subsalicylate - usage, dosage, interactions, images - AARP
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Do not treat diarrhea for more than 2 days without talking to your doctor or health care professional. Call your doctor or health care professional as soon as you can if you get a fever, or nausea and vomiting. These could be symptoms of a more serious illness ...
http://healthtools.aarp.org/goldcontent/bismuth-subsalicylate
Phenyl salicylate | definition of phenyl salicylate by Medical dictionaryPhenyl salicylate | definition of phenyl salicylate by Medical dictionary
Looking for online definition of phenyl salicylate in the Medical Dictionary? phenyl salicylate explanation free. What is phenyl salicylate? Meaning of phenyl salicylate medical term. What does phenyl salicylate mean?
https://medical-dictionary.thefreedictionary.com/phenyl+salicylate
Novel Nitric Oxide-Releasing Derivatives of Farnesylthiosalicylic Acid: Synthesis and Evaluation of Antihepatocellular...Novel Nitric Oxide-Releasing Derivatives of Farnesylthiosalicylic Acid: Synthesis and Evaluation of Antihepatocellular...
Close The Infona portal uses cookies, i.e. strings of text saved by a browser on the users device. The portal can access those files and use them to remember the users data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser. ...
https://www.infona.pl/resource/bwmeta1.element.acs-doi-10_1021_jm1014814
Novel Pathway of Salicylate Degradation by Streptomyces sp. Strain WA46 | Applied and Environmental MicrobiologyNovel Pathway of Salicylate Degradation by Streptomyces sp. Strain WA46 | Applied and Environmental Microbiology
Salicylate is produced by many plants and microbes and is widely distributed in nature. It has a variety of biological activities, most notably its role in human medicine as a member of an important anti-inflammatory drug class. Salicylate acts as a regulatory molecule for bacteria (49). The biosynthesis and natural degradation pathways of this simple organic molecule have been well studied. In this work, we have identified a salicylate degradation cluster (sdgABCDEFGHR) in Streptomyces sp. strain WA46 and shown that salicylate is initially converted to gentisate via salicylyl-CoA and gentisyl-CoA (Fig. 2 and 3A). Salicylate is presumably converted to salicylyl-CoA via salicylyl-AMP by the action of SdgA and SdgB. AMP ligases are key components in the biosynthesis of antibiotics and siderophores, in which specific substrates are activated by AMP addition (12, 20, 34, 50, 53); the activated adduct binds to the thiol group of biosynthetic enzymes or to an acyl carrier protein. We were unable to ...
https://aem.asm.org/content/70/3/1297
Vertebral malformations induced by sodium salicylate correlate with shifts in expression domains of Hox genes. | DIAL.pr -...Vertebral malformations induced by sodium salicylate correlate with shifts in expression domains of Hox genes. | DIAL.pr -...
Several embryotoxic agents, which includes sodium salicylate, were reported to induce vertebral variations in the form of supernumerary ribs (SNR) when administered to pregnant rodents. Because the biological significance of SNR in toxicological studies is still a matter of debate, we investigated the molecular basis of this defect by analyzing the possible involvement of Hox genes, known to specify vertebrae identity. Sodium salicylate (300mg/kg) was administered to pregnant rats on gestational day 9 (GD 9). On GD 13, the expression of several Hox genes, selected according to the position of their anterior limit of expression, namely upstream (Hoxa9), at the level (Hoxa10) and downstream (Hoxd9) to the morphological alteration, were analyzed. Posterior shifts in the anterior limit of expression of Hoxa10 and Hoxd9 were observed following exposure to salicylate, which could explain an effect at the level of the axial skeleton. This finding suggests that the appearance of ectopic ribs can be ...
https://dial.uclouvain.be/pr/boreal/object/boreal:10153
Prevention of Human Immunodeficiency Virus Type 1 Trans-mission by Pharmaceuticals Targeted to Host Proteins Re-quired for...Prevention of Human Immunodeficiency Virus Type 1 Trans-mission by Pharmaceuticals Targeted to Host Proteins Re-quired for...
Prevention of Human Immunodeficiency Virus Type 1 Trans-mission by Pharmaceuticals Targeted to Host Proteins Re-quired for Virus Infection? Consideration of Farnesyl Thiosalicylic Acid, a Ras Inhibitor Abstract.
https://www.omicsonline.org/peer-reviewed/prevention-of-human-immunodeficiency-virus-type-1-transmission-by-pharmaceuticals-targeted-to-host-proteins-required-for-virus-inf-193.html
Salicylate degradation by a cold-adapted Pseudomonas sp<...Salicylate degradation by a cold-adapted Pseudomonas sp<...
TY - JOUR. T1 - Salicylate degradation by a cold-adapted Pseudomonas sp. AU - Ahn, Eunsol. AU - Choi, Ki Young. AU - Kang, Beom Sik. AU - Zylstra, Gerben J.. AU - Kim, Dockyu. AU - Kim, Eungbin. N1 - Publisher Copyright: © 2017, Springer-Verlag Berlin Heidelberg and the University of Milan. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.. PY - 2017/6/1. Y1 - 2017/6/1. N2 - Pseudomonas sp. strain MC1 was characterized as a cold-adapted, naphthalene-degrading bacterium that is able to grow in a broad temperature range of 5-30°C. MC1 harbors a catabolic plasmid, designated pYIC1, which is almost identical to the archetypal NAH7 plasmid from the mesophilic bacterium Pseudomonas putida G7. On pYIC1, the catabolic genes for naphthalene degradation are clustered in two operons: nahAa-Ab-Ac-Ad-B-F-C-Q-E-D encoding the conversion of naphthalene to salicylate, and nahG-T-H-I-N-L-O-M-K-J encoding the conversion of salicylate through meta-cleavage pathway to pyruvate and acetyl CoA. NahH, ...
https://yonsei.pure.elsevier.com/en/publications/salicylate-degradation-by-a-cold-adapted-pseudomonas-sp
What Is the Chemical Formula for Sodium Salicylate? | Reference.comWhat Is the Chemical Formula for Sodium Salicylate? | Reference.com
The chemical formula for sodium salicylate is C7H5NaO3. All of the numbers in the chemical formula for sodium salicylate are subscript numbers in accordance with standard chemical formula...
https://www.reference.com/science/chemical-formula-sodium-salicylate-4ba87ac8b0eef6cc
RAS Inhibitors Not Linked to Increased Risk of Death from COVID-19 - - Global Oncology AcademyRAS Inhibitors Not Linked to Increased Risk of Death from COVID-19 - - Global Oncology Academy
Credit: Unsplash/CC0 Public Domain MedicalXpress.com Concerns have been raised that the use of a common group of medications called RAS inhibitors could facilitate SARS-CoV-2 infection, impact COVID-19 disease severity, and worsen prognosis. However, in a new nationwide registry-based study from Karolinska Institutet in Sweden, including almost 1.4 million patients, use of RAS inhibitors was not associated with increased risk of hospitalization or death from COVID-19. The study has been published in the European Journal of Heart Failure. The new coronavirus SARS-CoV-2 enters human cells by binding its outer spike protein to the angiotensin-converting enzyme 2 (ACE2) receptor on the target cells. Because renin-angiotensin-aldosterone-system (RAS) inhibitors increase ACE2 levels, concerns regarding the use of these treatments during the COVID-19 pandemic have been raised. The generic names of RAS inhibitors end in pril or sartan (some examples are enalapril, kaptopril, losartan
https://globaloncologyacademy.org/news/ras-inhibitors-not-linked-to-increased-risk-of-death-from-covid-19/1746023/
Salicylate uniquely induces a 27-kDa protein in tubercle bacillus<...
TY - JOUR. T1 - Salicylate uniquely induces a 27-kDa protein in tubercle bacillus. AU - Sun, Zhonghe. AU - Cheng, Shao Ji. AU - Zhang, Hao. AU - Zhang, Ying. PY - 2001/9/25. Y1 - 2001/9/25. N2 - Salicylate was found to uniquely induce a 27-kDa protein in Mycobacterium tuberculosis complex organisms but not in Mycobacterium smegmatis or Escherichia coli. The structural analogue antitubercular para-amino-salicylate also induced the 27-kDa protein but to a somewhat lower level than salicylate. Other structural analogues such as benzoic acid and acetyl salicylic acid (aspirin) did not induce the 27-kDa protein. Western blot analysis indicated that the 27-kDa protein was localized mainly in the cytoplasm. The 27-kDa protein was not expressed at different growth phases in the absence of salicylate. The 27-kDa protein was identified as a putative benzoquinone methyltransferase (Rv0560c), which has several homologues in the M. tuberculosis genome. The cloned 27-kDa gene was found to express ...
https://jhu.pure.elsevier.com/en/publications/salicylate-uniquely-induces-a-27-kda-protein-in-tubercle-bacillus-3
Sulfosalicylic Acid 10% Solution - Lab AlleySulfosalicylic Acid 10% Solution - Lab Alley
Buy Sulfosalicylic Acid, 10% (w/v) Aqueous Solution | 1 Liter Bottle | For Urine Tests | CAS # 97-05-2 | For Sale Online | Shipped By UPS In The U.S.
https://www.laballey.com/products/sulfo-salicylic-acid-10-solution
5-AMINO-3-SULFOSALICYLIC ACID | C7H7NO6S - PubChem5-AMINO-3-SULFOSALICYLIC ACID | C7H7NO6S - PubChem
5-AMINO-3-SULFOSALICYLIC ACID | C7H7NO6S | CID 22574 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/22574
IYPT 2019 Elements 083: Bismuth: Cosmetics and crackling fireworks - Compound InterestIYPT 2019 Elements 083: Bismuth: Cosmetics and crackling fireworks - Compound Interest
A bismuth compound, bismuth oxychloride, is used in some cosmetics to give either a matte or a shiny finish depending on particle size. Other bismuth compounds, bismuth(III) oxide and bismuth subcarbonate, are used in fireworks to give crackling effects. These compounds are formed into granules, the rapid combustion of which gives the crackling effect.. Bismuth-containing compounds are also found in medicines to treat stomach aches and diarrhoea. The best-known example is Pepto-Bismol (bismuth subsalicylate), an antacid.. Remember, you can keep track of all of the previous entries in this series on the site here, or on the Royal Society of Chemistrys dedicated page.. ...
https://www.compoundchem.com/2019/10/28/iypt083-bismuth/
Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases | Cell & Bioscience | Full...Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases | Cell & Bioscience | Full...
In the urgent campaign to develop therapeutics against SARS-CoV-2, natural products have been an important source of new lead compounds. We herein identified two natural products, ginkgolic acid and anacardic acid, as inhibitors using a high-throughput screen targeting the SARS-CoV-2 papain-like protease (PLpro). Moreover, our study demonstrated that the two hit compounds are dual inhibitors targeting the SARS-CoV-2 3-chymotrypsin-like protease (3CLpro) in addition to PLpro. A mechanism of action study using enzyme kinetics further characterized the two compounds as irreversible inhibitors against both 3CLpro and PLpro. Significantly, both identified compounds inhibit SARS-CoV-2 replication in vitro at nontoxic concentrations. Our finding provides two novel natural products as promising SARS-CoV-2 antivirals.
https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-021-00564-x
Salicylate Assay Kit | BioAssay SystemsSalicylate Assay Kit | BioAssay Systems
BioAssay Systems salicylate detection kit provides a convenient and reliable means to measure salicylate. In the assay, salicylate complexes with ferric chloride to create a colored compound that can be measured at 560 nm. This assay can be used with a variety of samples and is simple, sensitive, and adaptable to high-throughp
https://bioassaysys.com/Salicylate-Assay-Kit.html
Bonjela Teething Gel Oromucosal Gel | SPC | Reckitt Benckiser Ireland Limited | Medicines.ieBonjela Teething Gel Oromucosal Gel | SPC | Reckitt Benckiser Ireland Limited | Medicines.ie
i) Dealing with the potential for toxicity with local application, especially in infants:. As choline salicylate is absorbed across the buccal mucosa, the possibility exists for toxicity, especially in infants hence the need for caution not to exceed the stated dose and monitor for any signs of suggested salicylism.. Symptoms: Nausea, vomiting, tinnitus, hyperventilation, high fever, confusion, dehydration, disorientation, dizziness, coma and/or convulsions are common. Gastrointestinal haemorrhage is frequent. Some degree of acid-base disturbance is present in most cases.. ii) Dealing with overdose in the event of accidental ingestion of product:. Serum salicylate levels above 3.6 mmol/l in adults (2.2 mmol/l in children) are likely to be toxic and levels of 5.4 mmol/l or above are fatal.. Treatment: Drug absorption can be stopped by induced vomiting or gastric lavage within an hour of ingestion. Activated charcoal is to be given by mouth if the patient is suspected of ingesting more than ...
https://www.medicines.ie/medicines/bonjela-teething-gel-oromucosal-gel-31457/spc
minocyclineminocycline
If you also take bismuth salts (eg, bismuth subsalicylate), calcium salts (eg, calcium carbonate), colestipol, iron salts (eg, iron sulfate), magnesium, urinary alkalinizers (eg, daily antacids), sucralfate, vitamins/minerals, quinapril, didanosine, or zinc salts (eg, zinc sulfate), do not take them within 2 to 3 hours before or after taking Minocycline. Check with your doctor if you have questions ...
http://cure-plus.org/products/minocycline
buy-minocin-cheap-online
If you also take bismuth salts (eg, bismuth subsalicylate), calcium salts (eg, calcium carbonate), colestipol, iron salts (eg, iron sulfate), magnesium, urinary alkalinizers (eg, daily antacids), sucralfate, vitamins/minerals, quinapril, didanosine, or zinc salts (eg, zinc sulfate), do not take them within 2 to 3 hours before or after taking Minocin . Check with your doctor if you have questions ...
http://northern-pharmacy.com/products/minocin
Cure Pancreatic Cancer Ribbon - Emecweb OutlineCure Pancreatic Cancer Ribbon - Emecweb Outline
American Diabetes Association and the American Dietetic CEREALS/GRAINS/PASTA *Bran cereals concentrated (such as Bran Buds All Bran) Ingredient List: Active Ingredient: Bismuth subsalicylate 525 mg Inactive Ingredients: benzoic acid or pharmacist before use if you are taking any drug for: anticoagulation (thinning the blood) diabetes gout arthritis. Blood Glucose and Hormones - Insulin and Glucagon Antagonistic hormones 3. Cure Pancreatic Cancer Ribbon medication Diabetes Causes Fatigue :: Type 2 Diabetes Research For Cures - The 3 Step Trick that Reverses Diabetes Permanently in type 1 diabetes and gluten free diet As Little as 11 Days. en la historia evolutiva de la enfermedad al curar Health Concern On diagnosis or treatment.. Learn about their use side effects and safety warnings. There are several different types of rice including long-grain basmati black rice white rice and diabetes Brown Rice: Health Benefits & Nutrition Anti-phospho-Insulin Receptor Antibody clone 21G12 is an antibody ...
http://www.emecweb.eu/emec-diabetespaz/cure-pancreatic-cancer-ribbon/
Quick Answer: Does Pepto Bismol Kill H Pylori? - el-tejano
For H. pylori infection and duodenal ulcer (taken with an H2 blocker): Adults-One dose (two 262.4 milligrams [mg] of bismuth subsalicylate, one 250 mg of metronidazole, and one 500 mg of tetracycline) 4 times a day, taken with meals and at bedtime, for 14 days. Children-Use and dose must be determined by your doctor ...
https://el-tejano.com/qa/quick-answer-does-pepto-bismol-kill-h-pylori.html
Treatment strategies and outcomes of the study populati | Open-iTreatment strategies and outcomes of the study populati | Open-i
Treatment strategies and outcomes of the study population. OAC, omeprazole+amoxicillin+clarithromycin; BAM, bismuth subsalicylate+amoxicillin+metronidazole; UBT
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2721925_jkms-21-1037-g001&req=4
Coagulopathy Linked to Antidiarrheal Med Ingestion in Patient With Underlying Liver Disease - MPRCoagulopathy Linked to Antidiarrheal Med Ingestion in Patient With Underlying Liver Disease - MPR
A recently published report describes the case of a 62-year-old female patient with underlying cirrhosis who experienced coagulopathy secondary to bismuth subsalicylate (BSS) poisoning.
https://www.empr.com/home/news/coagulopathy-linked-to-antidiarrheal-med-ingestion-in-patient-with-underlying-liver-disease/
Morpholine salicylateMorpholine salicylate
... is a nonsteroidal anti-inflammatory drug. "Morpholine Salicylate". drugs.com. Koda A, Sakai K, Nagai H, ... Suzuki Y, Kobayashi T (September 1967). "[Pharmacological action of morpholine salicylate]". Nihon Yakurigaku Zasshi. Folia ...
https://en.wikipedia.org/wiki/Morpholine_salicylate
Copper salicylateCopper salicylate
... is a compound with formula Cu(C7H5O3). It is the copper salt of salicylic acid. A copper(II) monosalicylate ...
https://en.wikipedia.org/wiki/Copper_salicylate
Potassium salicylatePotassium salicylate
Salicylates, Potassium compounds, 3-Hydroxypropenals, All stub articles, Chemistry stubs). ... Potassium salicylate is the potassium salt of salicylic acid. http://www.chemicalbook.com/ChemicalProductProperty_EN_CB4157001. ...
https://en.wikipedia.org/wiki/Potassium_salicylate
Salicylate sensitivitySalicylate sensitivity
... is any adverse effect that occurs when a usual amount of salicylate is ingested. People with salicylate ... Salicylate sensitivity differs from salicylism, which occurs when an individual takes an overdose of salicylates. Salicylate ... Salicylate sensitivity can be treated with the use of low-salicylate diets, such as the Feingold Diet. The Feingold Diet ... Salicylates can also be found in many medications, perfumes and preservatives. Both natural and synthetic salicylates can cause ...
https://en.wikipedia.org/wiki/Salicylate_sensitivity
Ethyl salicylateEthyl salicylate
Methyl salicylate Isopropyl salicylate Pubchem. "Ethyl salicylate". pubchem.ncbi.nlm.nih.gov. Retrieved 25 February 2018. ... Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. It is a clear liquid that is sparingly ... "Fragrance material review on ethyl salicylate". Food and Chemical Toxicology. 45: S397-401. doi:10.1016/j.fct.2007.09.043. PMID ... Salicylate esters, 3-Hydroxypropenals, All stub articles, Ester stubs). ...
https://en.wikipedia.org/wiki/Ethyl_salicylate
Salicylate decarboxylaseSalicylate decarboxylase
... (EC 4.1.1.91, salicylic acid decarboxylase, Scd) is an enzyme with systematic name salicylate carboxy- ... Salicylate+decarboxylase at the US National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 4.1.1). ... This enzyme catalyses the following chemical reaction salicylate ⇌ {\displaystyle \rightleftharpoons } phenol + CO2 In the ... reverse direction the enzyme catalyses the regioselective carboxylation of phenol into salicylate. Kirimura K, Gunji H, ...
https://en.wikipedia.org/wiki/Salicylate_decarboxylase
Salicylate synthaseSalicylate synthase
... is an enzyme that catalyzes the chemical reaction: chorismate → salicylic acid MbtI is the responsible ... Zwahlen (January 30, 2007). "Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis". {{cite ...
https://en.wikipedia.org/wiki/Salicylate_synthase
Sodium salicylateSodium salicylate
... is of the salicylate family. It is used in medicine as an analgesic and antipyretic. Sodium salicylate also ... Wikimedia Commons has media related to Sodium salicylate. Chemicalland21 Some synonyms Safety data for sodium salicylate at ... Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher ... "sodium salicylate". chemister.ru. Retrieved 8 April 2018. Chambers, Michael. "ChemIDplus - 54-21-7 - ABBQHOQBGMUPJH-UHFFFAOYSA- ...
https://en.wikipedia.org/wiki/Sodium_salicylate
Trolamine salicylateTrolamine salicylate
Methyl salicylate From DailyMed (a publication of the National Institutes of Health) [1], retrieved 23 April 2011 Steven Pray, ... Trolamine salicylate (Aspercreme, Aspergel) is an organic compound which is the salt formed between triethanolamine and ... Due to health concerns, in 2019 the FDA issued a proposed rule classifying the sunscreen use of trolamine salicylate as "not ... Also, the producers of trolamine salicylate products have not provided evidence to the FDA in support of claims that this ...
https://en.wikipedia.org/wiki/Trolamine_salicylate
Isopropyl salicylateIsopropyl salicylate
Methyl salicylate Ethyl salicylate Pubchem. "Isopropyl salicylate". pubchem.ncbi.nlm.nih.gov. Retrieved 10 March 2021. " ... Isopropyl salicylate is the ester formed by the condensation of salicylic acid and isopropyl alcohol. It is a transparent ... "Isopropyl salicylate, 99%, ACROS Organics , Fisher Scientific". v t e (Articles without KEGG source, ECHA InfoCard ID from ... Salicylate esters, 3-Hydroxypropenals, All stub articles, Ester stubs). ...
https://en.wikipedia.org/wiki/Isopropyl_salicylate
Octyl salicylateOctyl salicylate
... , or 2-ethylhexyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to ... The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to ... Octisalate and all other salicylates have a good safety profile. It is often used to improve affinity and reduce ...
https://en.wikipedia.org/wiki/Octyl_salicylate
Salicylate testingSalicylate testing
... is a category of drug testing that is focused on detecting salicylates such as acetysalicylic acid for ... technology that can determine the presence and quantify salicylates. The introduction of a salicylate specific antigen labeled ... Salicylates can be identified by GC/MS, proton NMR, and IR.[citation needed] One of the first in vitro tests for aspirin was ... It is therefore possible to quantify the serum salicylate level through the signal strength-the amount of reflected light ...
https://en.wikipedia.org/wiki/Salicylate_testing
Estradiol salicylateEstradiol salicylate
... , or estradiol 3-salicylate, is a synthetic estrogen and estrogen ester - specifically, the C3 salicylic ... It is a metabolite of estradiol acetylsalicylate, which appears to be very rapidly hydrolyzed into estradiol salicylate. List ...
https://en.wikipedia.org/wiki/Estradiol_salicylate
Methyl salicylateMethyl salicylate
... is believed to function by being metabolized to the plant hormone salicylic acid. Since methyl salicylate is ... Salicylate, the major metabolite of methyl salicylate, may accumulate in blood, plasma or serum to confirm a diagnosis of ... Methyl salicylate can be produced by esterifying salicylic acid with methanol. Commercial methyl salicylate is now synthesized ... However, in the body it metabolizes into salicylates, including salicylic acid, a known NSAID. Methyl salicylate is used in low ...
https://en.wikipedia.org/wiki/Methyl_salicylate
Magnesium salicylateMagnesium salicylate
"Magnesium Salicylate Tablet - Uses, Side Effects, and More". WebMD. WebMD LLC. Retrieved March 30, 2022. "Magnesium Salicylate ... While magnesium salicylate is sold as an alternative for pain relief, it is still a nonsteroidal anti-inflammatory drug and, ... Magnesium salicylate is a common analgesic and nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate ... Magnesium salicylate can be an effective OTC alternative to prescription NSAIDs, with both anti-inflammatory and pain-relieving ...
https://en.wikipedia.org/wiki/Magnesium_salicylate
Phenyl salicylatePhenyl salicylate
... if he knew of a salicylate compound that lacked sodium salicylate's side effects. Nencki recommended phenyl salicylate, which ... Phenyl salicylate, or salol, is the organic compound with the formula C6H5O2C6H4OH. It is a white solid. It is occasionally ... Heating phenyl salicylate in turn gives xanthone. 2 C6H5O2C6H4OH → 2 C6H5OH + O[C6H4]2CO + CO2 In this conversion, phenol is ... Phenyl salicylate is used in school laboratory demonstrations on how cooling rates affect crystal size in igneous rocks, and ...
https://en.wikipedia.org/wiki/Phenyl_salicylate
Benzyl salicylateBenzyl salicylate
... is a salicylic acid benzyl ester, a chemical compound most frequently used in cosmetics as a fragrance ... ISBN 0-931710-37-5 "Benzyl salicylate". The Good Scents Company. Belsito, D; Bickers, D; Bruze, M; Calow, P; Greim, H; Hanifin ... Salicylates" (PDF). Food and Chemical Toxicology. 45 (Supplement 1): S1-23. doi:10.1016/j.fct.2007.09.087. PMID 18035463. " ...
https://en.wikipedia.org/wiki/Benzyl_salicylate
Salicylate poisoningSalicylate poisoning
... , also known as aspirin poisoning, is the acute or chronic poisoning with a salicylate such as aspirin. The ... High doses of salicylate can cause salicylate-induced tinnitus. The severity of toxicity depends on the amount of aspirin taken ... Oral sodium bicarbonate is contra-indicated in salicylate toxicity as it can cause dissociation of salicylate tablets in the GI ... is an effective method to increase the clearance of salicylates from the body. Alkalinization of the urine causes salicylates ...
https://en.wikipedia.org/wiki/Salicylate_poisoning
Salicylate 1-monooxygenaseSalicylate 1-monooxygenase
Other names in common use include salicylate hydroxylase, salicylate 1-hydroxylase, salicylate monooxygenase, and salicylate ... In enzymology, a salicylate 1-monooxygenase (EC 1.14.13.1) is an enzyme that catalyzes the chemical reaction salicylate + NADH ... doi:10.1016/0005-2744(69)90316-7. Takemori S, Yasuda H, Mihara K, Suzuki K, Katagiri M (1969). "Mechanism of the salicylate ... Suzuki K, Takemori S, Katagiri M (1969). "Mechanism of the salicylate hydroxylase reaction. IV. Fluorimetric analysis of the ...
https://en.wikipedia.org/wiki/Salicylate_1-monooxygenase
Trinder spot testTrinder spot test
Salicylate testing Leslie M. Shaw; Tai C Kwong; Barbarajean Magnani (2001). "Clinical Approach to the Poisoned Patient". The ... J.A. King; A.B. Sorrow; J.A. Finkelstein (1995). "Urine Trinder spot test: a rapid salicylate screen for the emergency ... The Trinder spot test is a diagnostic test used in medicine to determine exposure to salicylates, particularly to salicylic ... ISBN 978-1-890883-53-9. Neal Flomenbaum (2006). "Salicylates". In Lewis R. Goldfrank; Neal Flomenbaum; Mary Ann Howland; Robert ...
https://en.wikipedia.org/wiki/Trinder_spot_test
SpiraeaSpiraea
... contain salicylates. Acetylsalicylic acid was first isolated from Filipendula ulmaria,[citation needed] a species at ...
https://en.wikipedia.org/wiki/Spiraea
AloxiprinAloxiprin
Use with other salicylates. Use with NSAIDs. MIMS. "Aloxiprin". MIMS. Retrieved 16 April 2011. Encarta. "Aloxiprin". Encarta. ... People with allergies to salicylates. People with gastrointestinal ulcers. People with liver or kidney damage. Pregnant women ...
https://en.wikipedia.org/wiki/Aloxiprin
Salicylic acidSalicylic acid
Meanwhile, German scientists tried sodium salicylate with less success and more severe side effects. In 1979, salicylates were ... Salicylate may competitively inhibit prostaglandin formation. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) ... Other derivatives include methyl salicylate used as a liniment to soothe joint and muscle pain and choline salicylate used ... Methyl salicylate is taken up by the stomata of the nearby plant, where it can induce an immune response after being converted ...
https://en.wikipedia.org/wiki/Salicylic_acid
Edward Stone (natural philosopher)Edward Stone (natural philosopher)
175-. ISBN 978-1-4398-0774-3. K. D. Rainsford (22 October 2013). Aspirin and the Salicylates. Elsevier. p. 2. ISBN 978-1-4831- ... A less corrosive compound of salicylic acid, acetylsalicylic acid, produced by reacting sodium salicylate with acetyl chloride ...
https://en.wikipedia.org/wiki/Edward_Stone_(natural_philosopher)
AcetazolamideAcetazolamide
Salicylates, potential for severe toxicity. Sodium bicarbonate, potential for kidney stone formation. Anticoagulants, cardiac ...
https://en.wikipedia.org/wiki/Acetazolamide
Rheumatic feverRheumatic fever
Salicylates are useful for pain.[citation needed] Steroids are reserved for cases where there is evidence of an involvement of ... One should watch for side effects like gastritis and salicylate poisoning. In children and teenagers, the use of aspirin and ...
https://en.wikipedia.org/wiki/Rheumatic_fever
Uncoupling proteinUncoupling protein
ISBN 978-1-133-10879-5. "California Poison Control System: Salicylates". Archived from the original on 2014-08-02. Gong DW, He ...
https://en.wikipedia.org/wiki/Uncoupling_protein
AcetaminosalolAcetaminosalol
Brewster, R. Q. (1918). "ACETYLAMINOPHENYL SALICYLATE. THE PREPARATION OF SALOPHEN". Journal of the American Chemical Society. ... Salicylate esters, Acetanilides, Analgesics, 3-Hydroxypropenals, Phenol esters, All stub articles, Analgesic stubs, Ester stubs ...
https://en.wikipedia.org/wiki/Acetaminosalol
AspirinAspirin
Salicylate is also produced as a result of exposure to bismuth subsalicylate, methyl salicylate, and sodium salicylate. Aspirin ... Done AK (November 1960). "Salicylate intoxication. Significance of measurements of salicylate in blood in cases of acute ... Plasma salicylate levels in general range from 30 to 100 mg/L after usual therapeutic doses, 50-300 mg/L in people taking high ... Large doses of salicylate, a metabolite of aspirin, cause temporary tinnitus (ringing in the ears) based on experiments in rats ...
https://en.wikipedia.org/wiki/Aspirin
Poison Prevention Packaging Act of 1970Poison Prevention Packaging Act of 1970
Methyl salicylate. Liquid preparations containing more than 5% by weight of methyl salicylate, other than those packaged in ...
https://en.wikipedia.org/wiki/Poison_Prevention_Packaging_Act_of_1970
Salicylates Level: MedlinePlus Medical TestSalicylates Level: MedlinePlus Medical Test
Salicylates are a type of drug found in aspirin and other medicines. Salicylates are usually safe for adults when taken at the ... This test measures the amount of salicylates in blood. ... Salicylates are a type of drug found in many over-the-counter ... What is a salicylates level test?. This test measures the amount of salicylates in the blood. ... A salicylates level test is most often used to:. *Help diagnose acute or gradual aspirin poisoning. Acute aspirin poisoning ...
https://medlineplus.gov/lab-tests/salicylates-level/
Browsing by Subject SalicylatesBrowsing by Subject "Salicylates"
JavaScript is disabled for your browser. Some features of this site may not work without it ...
https://apps.who.int/iris/browse?authority=Salicylates&type=mesh
Surgeon Generals Advisory on the Use of Salicylates and Reye SyndromeSurgeon General's Advisory on the Use of Salicylates and Reye Syndrome
Surgeon Generals Advisory on the Use of Salicylates and Reye Syndrome Because the use of salicylates such as aspirin for ... advises against the use of salicylates and salicylate-containing medications for children with influenza and chickenpox.* ... the Surgeon General advises against use of salicylate and salicylate-containing medications for children with these diseases. ... The association of salicylates with Reye syndrome is based upon evidence from epidemiologic studies that are sufficiently ...
https://www.cdc.gov/mmwr/preview/mmwrhtml/00001108.htm
Salicylate Toxicity: Practice Essentials, Etiology and Pathophysiology, EpidemiologySalicylate Toxicity: Practice Essentials, Etiology and Pathophysiology, Epidemiology
... making salicylate toxicity an important cause of morbidity and mortality. (See Epidemiology. ... Salicylates are ubiquitous agents found in hundreds of over-the-counter (OTC) medications and in numerous prescription drugs, ... methyl salicylate (eg, oil of wintergreen; 98% salicylate), and Pepto-Bismol (236 mg of non-aspirin salicylate per 15 mL). ... Salicylate toxicity has been reported with the topical use of salicylate-containing teething gels in infants. [7] On the basis ...
https://www.medscape.com/answers/1009987-177734/what-is-the-pathophysiology-of-salicylate-toxicity
Browsing by Subject SalicylatesBrowsing by Subject "Salicylates"
JavaScript is disabled for your browser. Some features of this site may not work without it ...
https://extranet.who.int/iris/restricted/browse?locale-attribute=en&type=mesh&authority=Salicylates
DailyMed - PHYSOSTIGMINE SALICYLATE injectionDailyMed - PHYSOSTIGMINE SALICYLATE injection
Physostigmine Salicylate Injection is available in 2 mL ampules, each mL containing 1 mg of Physostigmine Salicylate in a ... PHYSOSTIGMINE SALICYLATE (UNII: 2046ZRO9VU) (PHYSOSTIGMINE - UNII:9U1VM840SP) PHYSOSTIGMINE SALICYLATE. 1 mg in 1 mL. ... PHYSOSTIGMINE SALICYLATE injection. To receive this label RSS feed. Copy the URL below and paste it into your RSS Reader ... Physostigmine Salicylate Injection is a derivative of the Calabar bean, and its active moiety, physostigmine, is also known as ...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=99006884-3bb6-4a51-8bfc-d826c2d66bec
Tea-Salicylate Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMDTea-Salicylate Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Find patient medical information for Tea-Salicylate topical on WebMD including its uses, side effects and safety, interactions ... Tea-Salicylate Cream - Uses, Side Effects, and More. Generic Name(S): trolamine salicylate View Free Coupon * Uses ... Before using trolamine salicylate, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other salicylates ... Trolamine salicylate is used to treat minor aches and pains of the muscles/joints (such as arthritis, backache, sprains). It ...
https://www.webmd.com/drugs/2/drug-61835/tea-salicylate-topical/details
Acetaminophen/magnesium salicylate/pamabrom Side Effects: Common, Severe, Long Term - Drugs.comAcetaminophen/magnesium salicylate/pamabrom Side Effects: Common, Severe, Long Term - Drugs.com
Learn about the potential side effects of acetaminophen/magnesium salicylate/pamabrom. Includes common and rare side effects ... Acetaminophen / magnesium salicylate / pamabrom Side Effects. Applies to acetaminophen / magnesium salicylate / pamabrom: oral ... Salicylates can cause Reyes syndrome, a serious and sometimes fatal condition in children. ...
https://www.drugs.com/sfx/acetaminophen-magnesium-salicylate-pamabrom-side-effects.html
Phenyl Salicylate, 500 g | Flinn ScientificPhenyl Salicylate, 500 g | Flinn Scientific
Phenyl Salicylate, 100 g. Flinn Lab Chemicals, Your Safer Source for Science ...
https://www.flinnsci.com/phenyl-salicylate-500-g/p0022/
Ammonium Salicylate pharmaceutical drugs and health productsAmmonium Salicylate pharmaceutical drugs and health products
Ammonium Salicylate indications and usages ATC and ICD codes, combinations with other active ingredients and trade names ... Ammonium Salicylate. Camphor. Ethyl Salicylate. Menthol. Methyl Salicylate Aspellin - Sanofi-Aventis. Radian B Pain Relief ... Ammonium Salicylate Salicyl-Vasogen - Pearson & Co.. Wulpyrin Ammonium Salicylate. Benzyl Nicotinate. Camphor. Capsicum ... Ammonium Salicylate. Camphor. Menthol. Methyl Salicylate. Salicylic Acid Radian B Muscle Lotion - Ransom. ...
https://drugs-about.com/ing/ammonium-salicylate.html
Triethanolamine salicylate. - NAPRATriethanolamine salicylate. - NAPRA
Receive NAPRA updates of interest directly to your inbox: general NAPRA news, NDS updates and/or updates on practice resources.. ...
https://www.napra.ca/nds/triethanolamine-salicylate-2/
New insights into signaling pathways of salicylate and metalloporphyrinsNew insights into signaling pathways of salicylate and metalloporphyrins
... Aim of the study: I. Salicylate and heme oxygenase-1: ... Aim of the study: I. Salicylate and heme oxygenase-1: The adhesion molecule P-selectin has been shown to be a major determinant ... salicylate, heme oxygenase, metalloporphyrins, caspases, endothelial cells. Subjects:. 500 Natural sciences and mathematics. ... Different pharmacological agents including salicylate have been shown to inhibit IL-4-induced P-selectin expression in ...
https://edoc.ub.uni-muenchen.de/3645/
Capsicum 0.32%, Methyl Salicylate 25% and Menthol 10% Analgesic CreamCapsicum 0.32%, Methyl Salicylate 25% and Menthol 10% Analgesic Cream
Methyl Salicylate 25% and Menthol 10% Analgesic Cream. Includes ingredients, method of preparation, discussion, and references ... Abstract: A formulation for preparing Capsicum 0.32%, Methyl Salicylate 25% and Menthol 10% Analgesic Cream. Includes ...
https://ijpc.com/abstracts/abstract.cfm?ABS=272
Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and...
Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and ... Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and ... Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and ... Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and ...
https://www.bmj.com/content/322/7296/1203/peer-review
Low Salicylate, Low Amine, Low Glutamate Recipes - Nourishing HopeLow Salicylate, Low Amine, Low Glutamate Recipes - Nourishing Hope
Egg-Free Chicken Nuggets GFCFSF/Low Oxalate/Low Salicylate, Egg-Free, and Nut-Free Use white vinegar for low salicylate. ... To make it low salicylate or SAG, use ghee or sunflower oil. For 100% dairy-free, avoid ghee. For keto, eat sparingly. ...
https://nourishinghope.com/low-salicylate-low-amine-low-glutamate-recipes/
Rheological and calorimetric study of alkyltrimethylammonium bromide-sodium salicylate wormlike micelles in aqueous binary...Rheological and calorimetric study of alkyltrimethylammonium bromide-sodium salicylate wormlike micelles in aqueous binary...
Rheological and calorimetric study of alkyltrimethylammonium bromide-sodium salicylate wormlike micelles in aqueous binary ... Rheological and calorimetric study of alkyltrimethylammonium bromide-sodium salicylate wormlike micelles in aqueous binary ... Rheological and calorimetric study of alkyltrimethylammonium bromide-sodium salicylate wormlike micelles in aqueous binary ... and sodium salicylate (NaSal). These types of self-assembly structures have viscoelastic properties, and the zero shear ...
https://www.americanelements.com/rheological-and-calorimetric-study-of-alkyltrimethylammonium-bromide-sodium-salicylate-wormlike
Production of high BN alkaline earth metal single-aromatic ring hydrocarbyl salicylate-carboxylate - Patent US-6348438-B1 -...Production of high BN alkaline earth metal single-aromatic ring hydrocarbyl salicylate-carboxylate - Patent US-6348438-B1 -...
US-6348438-B1 chemical patent summary.
https://pubchem.ncbi.nlm.nih.gov/patent/US-6348438-B1
An evidence based flowchart to guide the management of acute salicylate (aspirin) overdose | Emergency Medicine JournalAn evidence based flowchart to guide the management of acute salicylate (aspirin) overdose | Emergency Medicine Journal
An evidence based flowchart to guide the management of acute salicylate (aspirin) overdose ... An evidence based flowchart to guide the management of acute salicylate (aspirin) overdose ... An evidence based flowchart to guide the management of acute salicylate (aspirin) overdose ...
https://emj.bmj.com/content/19/3/206.share
Salicylate Free Fragrance?Salicylate Free Fragrance?
I am looking for a fragrance that i can use everyday that is Salicylate free. Any ideas? Our reply Hi Sue, thanks for your ... Salicylate Free Fragrance?. by Sue (Australia) I am looking for a fragrance that i can use everyday that is Salicylate free. ... Thats a great question! I am not an expert on salicylate free products, but I have never been able to find a salicylate free ... Natural fragrances such as essential oils contain a lot of salicylates. I am not sure how you would find a salicylate free ...
https://www.mysensitiveskincare.com/salicylate-free-fragrance.html
Cari Produk methyl salicylate di Apotik onlineCari Produk methyl salicylate di Apotik online
... methyl salicylate.. di apotik online yang Termurah, terlengkap, dan Terpercaya ...
https://medicastore.com/search/index?category=all&keyword=methyl+salicylate&page=3&per-page=12&filter=produk-terbaru
The structures of salicylate surfactants with long alkyl chains in non-aqueous media<...
The structures of salicylate surfactants with long alkyl chains in non-aqueous media. In: Langmuir. 2013 ; Vol. 29, No. 48. pp ... The structures of salicylate surfactants with long alkyl chains in non-aqueous media. Langmuir. 2013 Dec 3;29(48):14763-14771. ... The structures of salicylate surfactants with long alkyl chains in non-aqueous media. / Lee, Chern Leing; Dowding, Peter J.; ... Lee, CL, Dowding, PJ, Doyle, AR, Bakker, KM, Lam, SS, Rogers, SE & Routh, AF 2013, The structures of salicylate surfactants ...
https://research.monash.edu/en/publications/the-structures-of-salicylate-surfactants-with-long-alkyl-chains-i
Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug | The James Hutton InstituteInvestigation of salicylate hepatic responses in comparison with chemical analogues of the drug | The James Hutton Institute
Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug. Title. Investigation of ... Printed from /publications/investigation-salicylate-hepatic-responses-comparison-chemical-analogues-drug on 02/12/22 12:10:37 ...
https://www.hutton.ac.uk/publications/investigation-salicylate-hepatic-responses-comparison-chemical-analogues-drug
TROLAMINE SALICYLATE
Salicylate may competitively inhibit prostaglandin formation. Salicylates antirheumatic (nonsteroidal anti-inflammatory) ... TROLAMINE SALICYLATE Created by admin. on Fri Jun 25 20:58:24 UTC 2021. , Edited by admin. on Fri Jun 25 20:58:24 UTC 2021. ... Its salts, the salicylates, are used as analgesics. Salicylic acid treats acne by causing skin cells to slough off more readily ... Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes.. ...
https://drugs.ncats.io/substance/H8O4040BHD
Phenyl Salicylate
Properties: White, small crystals or crystalline powder; pleasant aromatic odor and taste. d 1.25; mp 41-43°; bp12 173°. One gram dissolves in 6670 ml water, 6 ml alcohol, 1.5 ml benzene, 5 ml amyl alcohol, 10 ml liq paraffin, 4 ml almond oil. Sol in acetone, chloroform, ether, oils; very slightly sol in glycerol. Solubility at 25° in g/100 g: absolute ethanol 53; ethyl acetate 470; methyl ethyl ketone 620; toluene 460; Stoddard solvent 88; water less than 0.1%. Incompat. Bromine water, ferric salts; camphor, monobromated camphor, phenol, chloral hydrate, thymol or urethan in trituration. ...
https://www.drugfuture.com/chemdata/Phenyl-Salicylate.html
Evaluation of methyl salicylate lures on populations of Typhlodromus pyri (Acari: Phytoseiidae) and other natural enemies in...Evaluation of methyl salicylate lures on populations of Typhlodromus pyri (Acari: Phytoseiidae) and other natural enemies in...
Evaluation of methyl salicylate lures on populations of Typhlodromus pyri (Acari: Phytoseiidae) and other natural enemies in ... Evaluation of methyl salicylate lures on populations of Typhlodromus pyri (Acari: Phytoseiidae) and other natural enemies in ... Evaluation of methyl salicylate lures on populations of Typhlodromus pyri (Acari: Phytoseiidae) and other natural enemies in ... Evaluation of methyl salicylate lures on populations of Typhlodromus pyri (Acari: Phytoseiidae) and other natural enemies in ...
https://cropandsoil.oregonstate.edu/biblio/evaluation-methyl-salicylate-lures-populations-typhlodromus-pyri-acari-phytoseiidae-and-other
Differential Growth Inhibition by the Aspirin Metabolite Salicylate in Human Colorectal Tumor Cell Lines: Enhanced Apoptosis in...Differential Growth Inhibition by the Aspirin Metabolite Salicylate in Human Colorectal Tumor Cell Lines: Enhanced Apoptosis in...
The effect of the aspirin metabolite salicylate on the growth of human colorectal tumor cell lines was determined. Salicylate ... Salicylate caused all cell lines to accumulate in G0-G1 and induced apoptosis in carcinoma and in vitro-transformed adenoma ... The ability of salicylate to induce cell cycle arrest and apoptosis and, in particular, the increased sensitivity of cells at ... In those adenoma lines that did show salicylate-induced apoptosis, the extent was considerably less than that in the more ...
https://aacrjournals.org/cancerres/article/56/10/2273/502406/Differential-Growth-Inhibition-by-the-Aspirin
Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug<...
In rat H4IIE hepatoma cells, salicylate was the only drug tested that activated AMPK. Salicylate also reduced mTOR signalling, ... In rat H4IIE hepatoma cells, salicylate was the only drug tested that activated AMPK. Salicylate also reduced mTOR signalling, ... In rat H4IIE hepatoma cells, salicylate was the only drug tested that activated AMPK. Salicylate also reduced mTOR signalling, ... In rat H4IIE hepatoma cells, salicylate was the only drug tested that activated AMPK. Salicylate also reduced mTOR signalling, ...
https://researchportal.hw.ac.uk/en/publications/investigation-of-salicylate-hepatic-responses-in-comparison-with-
Pfizer BioNTech Covid Vaccine and Salicylate increased, a phase IV clinical study of CDC and FDA data - eHealthMe
There is no Salicylate increased reported by people who get Pfizer BioNTech Covid Vaccine and have side effects. ... What is Salicylate Increased?. Salicylate increased is found to be associated with 22 drugs by eHealthMe. ... Salicylate increased in Johnson & Johnson COVID Vaccine Vaccine side effects by duration, gender, age and dose:. *Johnson & ... Pfizer BioNTech Covid Vaccine and Salicylate increased - a phase IV clinical study of CDC and FDA data Summary:. There is no ...
https://www.ehealthme.com/vs/pfizer-biontech-covid-vaccine/salicylate-increased/
Phenyl Salicylate, 99%, Crystal, NF - Antec, Inc.Phenyl Salicylate, 99%, Crystal, NF - Antec, Inc.
Phenyl Salicylate, 99%, Crystal, NF. CAS # 118-55-8 F.W. 214.22 Size. Size. 250 g. 500 g. 1 kg. Clear ...
https://www.kyantec.com/product/phenyl-salicylate-99-crystal-nf/
Dosing study on the effectiveness of salicylate/N-acetylcysteine for prevention of noise-induced hearing loss :<b>John Coleman...Dosing study on the effectiveness of salicylate/N-acetylcysteine for prevention of noise-induced hearing loss :<b>John Coleman...
Salicylate is an aspirin-related compound, distinct from aspirin. It was selected for this study due to its dual effects as an ... Dosing study on the effectiveness of salicylate/N-acetylcysteine for prevention of noise-induced hearing loss. John Coleman1, ... 7] Salicylate is chemically converted to dihydroxybenzoate (DHB) which is a specific scavenger of the (OH-) and DHB itself is ... 18] Salicylate may also inhibit NF-gamma B, a potential activator of inflammatory or cell death pathways, [19],[20] or induce ...
https://www.noiseandhealth.org/printarticle.asp?issn=1463-1741
MethylMentholCholineSodiumSalicylicAspirin and other salicylatesToxicitySerumIngestion of aspirinDrugsAnalogues of the drugAnalgesicsConcentrationsTrolamineDosesInhibitFragranceReye'sPoisoningMedicationsLiquids2021MedicinalBenzylGLYCERINOxalatesTriethanolamineTopicalEvaluationResponsesDoseAdultDiagnosisEnzymeDerivativeEssential oilsAMPKChickenFoundSymptomsIllness
Methyl8
  • Ingestion of topical products containing salicylates (eg, Ben-Gay, salicylic acid [keratolytic], oil of wintergreen or methyl salicylate), can cause severe salicylate toxicity. (medscape.com)
  • According to published sources, one teaspoon of 98% methyl salicylate contains as much as 7000 mg of salicylate, the equivalent of nearly 90 baby aspirins and more than 4 times the potentially toxic dose for a child who weighs 10 kg. (medscape.com)
  • [ 7 ] On the basis of a literature review, Greene et al estimated the allowable daily intake of methyl salicylate to be 11 mg/kg/d. (medscape.com)
  • A comprehensive review of the existing medical literature on methyl salicylate poisoning has determined that it is a relatively common source of pediatric exposures. (medscape.com)
  • Menthol and methyl salicylate are known as counterirritants. (blinkhealth.com)
  • Further down the salicylic acid chain, Seqens EDS offers a comprehensive portfolio of Methyl Salicylate grades. (seqens.com)
  • The glue vapors consisted of methyl- salicylate (119368), o-phenylphenol (90437), and various terpene or terpene derivative compounds. (cdc.gov)
  • Menthol, Methyl Salicylate, Pine oil. (tongbos.com)
Menthol1
  • Mint, mint oils, and menthol are all very high in salicylates so if you are sensitive or allergic to salicylates, it's necessary to leave mint and mint flavoring out of all personal care products. (cleure.com)
Choline4
  • Physostigmine Salicylate Injection should not be used in the presence of asthma, gangrene, diabetes, cardiovascular disease, mechanical obstruction of the intestine or urogenital tract or any vagotonic state, and in patients receiving choline esters and depolarizing neuromuscular blocking agents (decamethonium, succinylcholine). (nih.gov)
  • These drugs include magnesium choline salicylate, sodium salicy-late, and salicyl salicylate. (brainkart.com)
  • b) in the case of choline salicylate, 435 mg. (gc.ca)
  • Choline magnesium trisalicylate is in a class of nonsteroidal anti-inflammatory medications (NSAIDs) called salicylates. (epnet.com)
Sodium5
  • Physostigmine Salicylate Injection is available in 2 mL ampules, each mL containing 1 mg of Physostigmine Salicylate in a vehicle composed of sodium metabisulfite 0.1%, benzyl alcohol 2.0% as a preservative in Water for Injection. (nih.gov)
  • Rheological and calorimetric study of alkyltrimethylammonium bromide-sodium salicylate wormlike micelles in aqueous binary systems. (americanelements.com)
  • This hypothesis was previously extended to wormlike micelles (WLM) of cetyltrimethylammonium bromide (CTAB) and sodium salicylate (NaSal). (americanelements.com)
  • The efficacy of three different doses of sodium salicylate (SAL) in combination with one dose of N-acetylcysteine (NAC) to prevent noise-induced hearing loss was studied in chinchillas. (noiseandhealth.org)
  • Le Gloss T Colour Gel 1253392 F: Aqua/Water/Eau Cetearyl Alcohol Cocamidopropyl Betaine Behentrimonium Chloride Propylene Glycol Amodimethicone, Sclerotium Gum Hc Blue 2 Isopropyl Alcohol Sodium Chloride Phenoxyethanol Parfum/Fragrance Ethanolamine, Citric Acid 2-Nitro-5-Glyceryl Methylaniline Cocos Nucifera Oil/Coconut Oil Trideceth-6 Lunalool Hexyl Cinnamal Chlorhexidine Digluconate Basic Brown 17, Benzyl Salicylate Benzyl Alcohol Limonene Cetrimonium Chloride Amyl Cinnamal Coumarin Citronellol Alpha-Isomethyl Ionone, F.I.L. (cub.com)
Salicylic3
  • Salicylates are a group of chemicals derived from salicylic acid which are found naturally in certain plants and synthetically in products like medications, toothpaste, and food preservatives. (cleure.com)
  • Benzyl salicylate is a synthetic chemical produced for industry from benzyl alcohol and salicylic acid, however it can be found naturally in some plants and plant extracts, such as hyacinth flower oil and ylang-ylang oil. (ecostore.com)
  • Betaine salicylate combines perfectly the benefits of salicylic acid with the unique and gentle skin improvement properties,it can improve skin conditions wildly,that has antimicrobial properties and exfoliating ,moisturizing functions. (zhonglanindustry.com)
Aspirin and other salicylates3
  • Aspirin and other salicylates are most often used to reduce pain , fever , and inflammation. (medlineplus.gov)
  • But aspirin and other salicylates are usually safe and effective for adults when taken at the proper dose. (medlineplus.gov)
  • These studies conducted by state health departments suggest an association between prior ingestion of aspirin and other salicylates and Reye syndrome. (cdc.gov)
Toxicity5
  • Salicylate toxicity has been reported with the topical use of salicylate-containing teething gels in infants. (medscape.com)
  • In a study of 599 cases of salicylate exposure in children less than 6 years old, the majority of children with signs of salicylate toxicity (metabolic acidosis, tachypnea) were exposed to liquid preparations. (medscape.com)
  • The acid-base, fluid, and electrolyte abnormalities seen with salicylate toxicity can be grouped into phases. (medscape.com)
  • Salicylate toxicity increases CNS utilization of glucose, serum glucose levels may not reflect CNS levels. (wikem.org)
  • Salicylate toxicity is the great toxicologic mimicker! (emclerkship.com)
Serum2
  • The nonacetylated salicylates are administered in doses up to 3-4 g of salicylate a day and can be monitored using serum salicy-late measurements. (brainkart.com)
  • Loop Diuretics may increase the serum concentration of Salicylates. (genericpedia.com)
Ingestion of aspirin1
  • Although concentrations of salicylate persist following ingestion of aspirin tablets, it has been shown that the majority of salicylate concentrations declined following ingestion of salicylate as acetylsalicylic powder. (medscape.com)
Drugs5
  • The Surgeon General notes that the FDA will notify health professionals through its Drug Bulletin, will develop lay-language information for widespread distribution, and will take the steps necessary to establish new labeling requirements for drugs containing salicylates. (cdc.gov)
  • It belongs to a class of drugs known as salicylates . (webmd.com)
  • Salicylate increased is found to be associated with 22 drugs by eHealthMe. (ehealthme.com)
  • All nonacetylated salicylates are effective anti-inflammatory drugs, although they may be less effective anal-gesics than aspirin. (brainkart.com)
  • Treatment with mesalazine was initially started in 2015 before being withdrawn because of the inflammatory condition of the patient refractory to salicylates drugs. (lww.com)
Analogues of the drug1
  • Here, we have gauged the contribution of these effects to control of hepatocyte glucose production, comparing salicylate with inactive hydroxybenzoic acid analogues of the drug. (hw.ac.uk)
Analgesics2
  • However, the incidence of salicylate poisoning in children has declined because of reliance on alternative analgesics and the use of child-resistant containers. (medscape.com)
  • Its salts, the salicylates, are used as analgesics. (ncats.io)
Concentrations1
  • In one study, salicylate concentrations increased or changed insignificantly in 50% of patients who ingested tablets, but following powder ingestions, concentrations declined in 94% of cases. (medscape.com)
Trolamine1
  • Trolamine salicylate is used to treat minor aches and pains of the muscles/joints (such as arthritis , backache, sprains). (webmd.com)
Doses1
  • We found, for example, that H4IIE cells were exquisitely sensitive to uncoupling with modest doses of salicylate, which occurred on a similar time course to another anti-hyperglycaemic uncoupling agent 2,4-dinitrophenol, while there was no discernible effect at all of two salicylate analogues which are not anti-hyperglycaemic. (hw.ac.uk)
Inhibit4
  • Different pharmacological agents including salicylate have been shown to inhibit IL-4-induced P-selectin expression in endothelial cells. (uni-muenchen.de)
  • Salicylate may competitively inhibit prostaglandin formation. (ncats.io)
  • This is in contrast to salicylates (eg, aspirin), which irreversibly bind to COX and inhibit production for the entire life of the cell, or acetaminophen, which inhibits COX centrally. (medscape.com)
  • In particular, salicylate was found to potently activate AMPK, a kinase known to inhibit HAS2 activity, and caused a dose -dependent decrease of cell associated (intracellular and membrane -bound) as well as secreted hyaluronan , followed by the down-regulation of HAS2 and the induction of HYAL-2 and CD44 in metastatic breast cancer cells . (bvsalud.org)
Fragrance5
Reye's2
  • Reye's syndrome and salicylate use. (cdc.gov)
  • Salicylates can cause Reye's syndrome, a serious and sometimes fatal condition in children. (drugs.com)
Poisoning4
  • However, if you take too much, it can cause a serious and sometimes fatal condition called salicylate or aspirin poisoning. (medlineplus.gov)
  • Salicylate ingestion continues to be a common cause of poisoning in children and adolescents. (medscape.com)
  • Therefore, consider salicylate poisoning when topical herbal medicinal oil is involved. (medscape.com)
  • A case of neonatal salicylate poisoning due to administration of this medicine as a colic reliever has been reported. (medscape.com)
Medications2
  • Because the use of salicylates such as aspirin for children with influenza and chickenpox has been associated with Reye syndrome, the Surgeon General advises against use of salicylate and salicylate-containing medications for children with these diseases. (cdc.gov)
  • advises against the use of salicylates and salicylate-containing medications for children with influenza and chickenpox. (cdc.gov)
Liquids1
  • Salicylate is available for ingestion as tablets, capsules, and liquids. (medscape.com)
20211
  • Retrieved September 29, 2021 from https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-salicylate. (ecostore.com)
Medicinal1
  • Salicylates are natural anti-inflammatory and medicinal substances found in plants, which are the active ingredient in aspirin. (mysensitiveskincare.com)
Benzyl4
  • Benzyl Salicylate is used as an odor molecule in scented products. (wellacompany.com)
  • Benzyl salicylate is an aromatic chemical, usually appearing as a clear liquid with a mild sweet floral odour. (ecostore.com)
  • Benzyl salicylate: a survey of consumer patch-test sensitization. (ecostore.com)
  • PubChem Compound Summary for CID 8363, Benzyl salicylate. (ecostore.com)
GLYCERIN1
  • That being said, I do know of one brand of ***z-cleure-salicylate-free-glycerin-soap.shtml*** which is lightly scented. (mysensitiveskincare.com)
Oxalates1
  • This is my favorite i f you're looking for a list of symptoms and which one of the many chemical constituents it might be, such as salicylates, oxalates, histamines, and more. (loricoultrup.com)
Triethanolamine1
Topical1
  • Salicylate is also available for topical application, in creams or lotions. (medscape.com)
Evaluation1
  • We report on the virtual screening, synthesis, and biological evaluation of new furan derivatives targeting Mycobacterium tuberculosis salicylate synthase (MbtI). (unimi.it)
Responses2
  • Aim of the study: I. Salicylate and heme oxygenase-1: The adhesion molecule P-selectin has been shown to be a major determinant of inflammatory responses. (uni-muenchen.de)
  • Using the salicylate-induced model of tinnitus and hyperacusis, we found that long-latency (>10 ms) sound-evoked response components in both the brain regions were significantly enhanced after salicylate administration, while the short-latency responses were reduced, likely reflecting cochlear hearing loss. (cdc.gov)
Dose2
  • Salicylate showed dose-dependent inhibitory effects on all of the cell lines (IC 50 , 1.65 ± 0.36 to 7.38 ± 1.08 m m ), yet carcinoma and in vitro -transformed adenoma cell lines were more sensitive than adenoma cell lines. (aacrjournals.org)
  • Finally, we demonstrate that salicylate results in an increase in corticosterone level in a dose-dependent manner consistent with the notion that stress may interact with hearing loss in tinnitus and hyperacusis development. (cdc.gov)
Adult1
  • C.09.032 (1) Subject to subsections (2) and (3) and section C.09.035, a salicylate product in the form of a tablet, capsule or other solid dosage form intended for oral administration shall contain one adult standard dosage unit of a salicylate per individual dosage form. (gc.ca)
Diagnosis1
  • Dramatic reversal of the effects of anticholinergic symptoms can be expected in minutes after the intravenous administration of Physostigmine Salicylate Injection, if the diagnosis is correct and the patient has not suffered anoxia or other insult. (nih.gov)
Enzyme1
  • In a sub-panel of analogues, salicylate alone reduced promoter activity of the key gluconeogenic enzyme glucose 6-phosphatase and suppressed basal glucose production in mouse primary hepatocytes. (hw.ac.uk)
Derivative1
  • Physostigmine Salicylate Injection is a derivative of the Calabar bean, and its active moiety, physostigmine, is also known as eserine. (nih.gov)
Essential oils1
AMPK3
  • In rat H4IIE hepatoma cells, salicylate was the only drug tested that activated AMPK. (hw.ac.uk)
  • Both salicylate and 2,6 dihydroxybenzoic acid suppressed TNFα-induced IκB degradation, and in genetic knockout experiments, we found that the effect of salicylate on IκB degradation was AMPK-independent. (hw.ac.uk)
  • Previous data also identified AMPK-independent regulation of glucose but we found that direct inhibition of neither NF-κB nor mTOR signalling suppressed glucose production, suggesting that other factors besides these cell signalling pathways may need to be considered to account for this response to salicylate. (hw.ac.uk)
Chicken1
  • Egg-Free Chicken Nuggets GFCFSF/Low Oxalate/Low Salicylate, Egg-Free, and Nut-Free Use white vinegar for low salicylate. (nourishinghope.com)
Found2
  • Salicylates are a type of drug found in many over-the-counter and prescription medicines. (medlineplus.gov)
  • Salicylate is a natural substance thatcan be found in many foods, such as almonds, tomatoes, grapes and apples. (medguidance.com)
Symptoms1
  • If excessive symptoms of salivation, emesis, urination and defecation occur, the use of Physostigmine Salicylate Injection should be terminated. (nih.gov)
Illness1
  • CDC, on the basis of its review of the available data and the recommendations of an advisory panel on February 12, 1982, stated that 'until definitive information is available, CDC advises physicians and parents of the possible increased risk of Reye syndrome associated with the use of salicylates for children with chickenpox and influenza-like illness' (3). (cdc.gov)
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