The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
An agency in the Executive Branch of the Federal Government. It was created as an independent regulatory agency responsible for the implementation of federal laws designed to protect the environment. Its mission is to protect human health and the ENVIRONMENT.
Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.
An array of tests used to determine the toxicity of a substance to living systems. These include tests on clinical drugs, foods, and environmental pollutants.
The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.
The science concerned with the detection, chemical composition, and biological action of toxic substances or poisons and the treatment and prevention of toxic manifestations.
The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.
The study of ENVIRONMENTAL POLLUTION and the toxic effects of ENVIRONMENTAL POLLUTANTS on the ECOSYSTEM. The term was coined by Truhaut in 1969.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Evaluation of the nature and extent of nursing problems presented by a patient for the purpose of patient care planning.
Procedures, such as TISSUE CULTURE TECHNIQUES; mathematical models; etc., when used or advocated for use in place of the use of animals in research or diagnostic laboratories.
The process of minimizing risk to an organization by developing systems to identify and analyze potential hazards to prevent accidents, injuries, and other adverse occurrences, and by attempting to handle events and incidents which do occur in such a manner that their effect and cost are minimized. Effective risk management has its greatest benefits in application to insurance in order to avert or minimize financial liability. (From Slee & Slee: Health care terms, 2d ed)
The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The maximum exposure to a biologically active physical or chemical agent that is allowed during an 8-hour period (a workday) in a population of workers, or during a 24-hour period in the general population, which does not appear to cause appreciable harm, whether immediate or delayed for any period, in the target population. (From Lewis Dictionary of Toxicology, 1st ed)
Carcinogenic substances that are found in the environment.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.
Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water.
The predisposition to tooth decay (DENTAL CARIES).
The science of controlling or modifying those conditions, influences, or forces surrounding man which relate to promoting, establishing, and maintaining health.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
The highest dosage administered that does not produce toxic effects.
Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).
The study of existing genetic knowledge, and the generation of new genetic data, to understand and thus avoid DRUG TOXICITY and adverse effects from toxic substances from the environment.
Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.
Elements of limited time intervals, contributing to particular results or situations.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Evaluation of the level of physical, physiological, or mental functioning in the older population group.
Chlorinated hydrocarbons containing heteroatoms that are present as contaminants of herbicides. Dioxins are carcinogenic, teratogenic, and mutagenic. They have been banned from use by the FDA.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.
Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.
Substances which pollute the soil. Use for soil pollutants in general or for which there is no specific heading.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Chemical substances that are foreign to the biological system. They include naturally occurring compounds, drugs, environmental agents, carcinogens, insecticides, etc.
A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
The exposure to potentially harmful chemical, physical, or biological agents by inhaling them.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Systematic identification of a population's needs or the assessment of individuals to determine the proper level of services needed.
The measurement of the health status for a given population using a variety of indices, including morbidity, mortality, and available health resources.
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Falls due to slipping or tripping which may result in injury.
Acquiring information from a patient on past medical conditions and treatments.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
Detection of a MUTATION; GENOTYPE; KARYOTYPE; or specific ALLELES associated with genetic traits, heritable diseases, or predisposition to a disease, or that may lead to the disease in descendants. It includes prenatal genetic testing.
An educational process that provides information and advice to individuals or families about a genetic condition that may affect them. The purpose is to help individuals make informed decisions about marriage, reproduction, and other health management issues based on information about the genetic disease, the available diagnostic tests, and management programs. Psychosocial support is usually offered.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Cultivated plants or agricultural produce such as grain, vegetables, or fruit. (From American Heritage Dictionary, 1982)
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The collective designation of three organizations with common membership: the European Economic Community (Common Market), the European Coal and Steel Community, and the European Atomic Energy Community (Euratom). It was known as the European Community until 1994. It is primarily an economic union with the principal objectives of free movement of goods, capital, and labor. Professional services, social, medical and paramedical, are subsumed under labor. The constituent countries are Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden, and the United Kingdom. (The World Almanac and Book of Facts 1997, p842)
A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.
Evaluation and measurement of nutritional variables in order to assess the level of nutrition or the NUTRITIONAL STATUS of the individual. NUTRITION SURVEYS may be used in making the assessment.
The promotion and maintenance of physical and mental health in the work environment.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
Waste products which threaten life, health, or the environment when improperly treated, stored, transported, disposed of, or otherwise managed.
Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or material. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS.
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.
Means or process of supplying water (as for a community) usually including reservoirs, tunnels, and pipelines and often the watershed from which the water is ultimately drawn. (Webster, 3d ed)
Contamination of the air, bodies of water, or land with substances that are harmful to human health and the environment.
Substances or organisms which pollute the water or bodies of water. Use for water pollutants in general or those for which there is no specific heading.
Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.
Activities involved in ensuring the safety of FOOD including avoidance of bacterial and other contamination.
Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
The capability to perform acceptably those duties directly related to patient care.
The external elements and conditions which surround, influence, and affect the life and development of an organism or population.
Pesticides or their breakdown products remaining in the environment following their normal use or accidental contamination.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
The condition in which reasonable knowledge regarding risks, benefits, or the future is not available.
The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.
Tumors or cancer of the human BREAST.
Mathematical or statistical procedures used as aids in making a decision. They are frequently used in medical decision-making.
Uptake of substances through the SKIN.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect.
Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.
An infant during the first month after birth.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Any enterprise centered on the processing, assembly, production, or marketing of a line of products, services, commodities, or merchandise, in a particular field often named after its principal product. Examples include the automobile, fishing, music, publishing, insurance, and textile industries.
Exercise of governmental authority to control conduct.
Release of oil into the environment usually due to human activity.
The assessing of academic or educational achievement. It includes all aspects of testing and test construction.
Evaluation of biomedical technology in relation to cost, efficacy, utilization, etc., and its future impact on social, ethical, and legal systems.
An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)
Diseases caused by factors involved in one's employment.
Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.
General agreement or collective opinion; the judgment arrived at by most of those concerned.
A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Assessment of psychological variables by the application of mathematical procedures.
Administrative units of government responsible for policy making and management of governmental activities.
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
Standards for limiting worker exposure to airborne contaminants. They are the maximum concentration in air at which it is believed that a particular substance will not produce adverse health effects with repeated daily exposure. It can be a time-weighted average (TLV-TWA), a short-term value (TLV-STEL), or an instantaneous value (TLV-Ceiling). They are expressed either as parts per million (ppm) or milligram per cubic meter (mg/m3).
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Metals with high specific gravity, typically larger than 5. They have complex spectra, form colored salts and double salts, have a low electrode potential, are mainly amphoteric, yield weak bases and weak acids, and are oxidizing or reducing agents (From Grant & Hackh's Chemical Dictionary, 5th ed)
An institute of the CENTERS FOR DISEASE CONTROL AND PREVENTION which is responsible for assuring safe and healthful working conditions and for developing standards of safety and health. Research activities are carried out pertinent to these goals.
A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794)
Air pollutants found in the work area. They are usually produced by the specific nature of the occupation.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
A chemical by-product that results from burning or incinerating chlorinated industrial chemicals and other hydrocarbons. This compound is considered an environmental toxin, and may pose reproductive, as well as, other health risks for animals and humans.
A nursing specialty involving nursing care given to the pregnant patient before, after, or during childbirth.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
The total amount of a chemical, metal or radioactive substance present at any time after absorption in the body of man or animal.
Application of statistical procedures to analyze specific observed or assumed facts from a particular study.
The study of chance processes or the relative frequency characterizing a chance process.
Psychiatry in its legal aspects. This includes criminology, penology, commitment of mentally ill, the psychiatrist's role in compensation cases, the problems of releasing information to the court, and of expert testimony.
The study of aquatic life inhabiting bodies of water, including growth, morphology, physiology, genetics, distribution, and interactions with other organisms and the environment. It includes MARINE HYDROBIOLOGY.
Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)
Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.
A course or method of action selected, usually by a government, from among alternatives to guide and determine present and future decisions.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.
Place or physical location of work or employment.
The branch of dentistry concerned with the prevention of disease and the maintenance and promotion of oral health.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
A graphic device used in decision analysis, series of decision options are represented as branches (hierarchical).
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
The development of systems to prevent accidents, injuries, and other adverse occurrences in an institutional setting. The concept includes prevention or reduction of adverse events or incidents involving employees, patients, or facilities. Examples include plans to reduce injuries from falls or plans for fire safety to promote a safe institutional environment.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)
Studies designed to examine associations, commonly, hypothesized causal relations. They are usually concerned with identifying or measuring the effects of risk factors or exposures. The common types of analytic study are CASE-CONTROL STUDIES; COHORT STUDIES; and CROSS-SECTIONAL STUDIES.
Conformity in fulfilling or following official, recognized, or institutional requirements, guidelines, recommendations, protocols, pathways, or other standards.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS.
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
Specific practices for the prevention of disease or mental disorders in susceptible individuals or populations. These include HEALTH PROMOTION, including mental health; protective procedures, such as COMMUNICABLE DISEASE CONTROL; and monitoring and regulation of ENVIRONMENTAL POLLUTANTS. Primary prevention is to be distinguished from SECONDARY PREVENTION and TERTIARY PREVENTION.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
The science, art or practice of cultivating soil, producing crops, and raising livestock.
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, Sint Maarten, formerly included in the NETHERLANDS ANTILLES.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
Presentation of pertinent data by one with special skill or knowledge representing mastery of a particular subject.
The contamination of indoor air.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
International organizations which provide health-related or other cooperative services.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Provision of physical and biological barriers to the dissemination of potentially hazardous biologically active agents (bacteria, viruses, recombinant DNA, etc.). Physical containment involves the use of special equipment, facilities, and procedures to prevent the escape of the agent. Biological containment includes use of immune personnel and the selection of agents and hosts that will minimize the risk should the agent escape the containment facility.
A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Research techniques that focus on study designs and data gathering methods in human and animal populations.
The branch of science concerned with the interrelationship of organisms and their ENVIRONMENT, especially as manifested by natural cycles and rhythms, community development and structure, interactions between different kinds of organisms, geographic distributions, and population alterations. (Webster's, 3d ed)
Planned management, use, and preservation of energy resources.
Individual or group aggressive behavior which is socially non-acceptable, turbulent, and often destructive. It is precipitated by frustrations, hostility, prejudices, etc.
A chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations. Its primary use is as a solvent in manufacturing and food technology.
The decision process by which individuals, groups or institutions establish policies pertaining to plans, programs or procedures.
Collection, analysis, and interpretation of data about the frequency, distribution, and consequences of disease or health conditions, for use in the planning, implementing, and evaluating public health programs.
The system of glands that release their secretions (hormones) directly into the circulatory system. In addition to the ENDOCRINE GLANDS, included are the CHROMAFFIN SYSTEM and the NEUROSECRETORY SYSTEMS.
A plant growing in a location where it is not wanted, often competing with cultivated plants.
The presence of contaminants or pollutant substances in the air (AIR POLLUTANTS) that interfere with human health or welfare, or produce other harmful environmental effects. The substances may include GASES; PARTICULATE MATTER; or volatile ORGANIC CHEMICALS.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Studies designed to assess the efficacy of programs. They may include the evaluation of cost-effectiveness, the extent to which objectives are met, or impact.
Knowledge, attitudes, and associated behaviors which pertain to health-related topics such as PATHOLOGIC PROCESSES or diseases, their prevention, and treatment. This term refers to non-health workers and health workers (HEALTH PERSONNEL).
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.
A weight-carrying structure for navigation of the air that is supported either by its own buoyancy or by the dynamic action of the air against its surfaces. (Webster, 1973)
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.
Care which provides integrated, accessible health care services by clinicians who are accountable for addressing a large majority of personal health care needs, developing a sustained partnership with patients, and practicing in the context of family and community. (JAMA 1995;273(3):192)
Regulations to assure protection of property and equipment.
A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.
The protection, preservation, restoration, and rational use of all resources in the total environment.
Approximate, quantitative reasoning that is concerned with the linguistic ambiguity which exists in natural or synthetic language. At its core are variables such as good, bad, and young as well as modifiers such as more, less, and very. These ordinary terms represent fuzzy sets in a particular problem. Fuzzy logic plays a key role in many medical expert systems.
Breaks in bones.
Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.

Does risk factor epidemiology put epidemiology at risk? Peering into the future. (1/30946)

The multiple cause black box paradigm of the current risk factor era in epidemiology is growing less serviceable. This single level paradigm is likely to be displaced. The signs are that the growing strength of molecular epidemiology on the one side, and of a global epidemiology based on information systems on the other, will come to dominate epidemiology and segregate it into separate disciplines. At the same time, the links with public health interests grow weaker. A multilevel ecoepidemiology has the potential to bind these strands together.  (+info)

Hepatitis B--are surgeons putting patients at risk? (2/30946)

The 1993 Department of Health guidelines permit a surgeon who is hepatitis B surface antigen (HBsAg) positive but e-antigen (HBeAg) negative to perform exposure prone procedures, unless demonstrated to have infected patients. However, there is increasing evidence of transmission of hepatitis B to patients from health care workers in this supposedly low infectivity category. The Occupational Physician must decide whether existing guidelines represent an adequate risk assessment and indeed whether this is an acceptable risk for patients. If an NHS Trust continues to follow these guidelines it may be in breach of its duty of care to patients. Yet refusing to allow such carriers to operate without testing for additional serological markers may be unlawful discrimination. Further research is clearly needed as well as an urgent review of the guidelines.  (+info)

Contact dermatitis in Alstroemeria workers. (3/30946)

Hand dermatitis is common in workers in the horticultural industry. This study determined the prevalence of hand dermatitis in workers of Alstroemeria cultivation, investigated how many workers had been sensitized by tulipalin A (the allergen in Alstroemeria) and took stock of a wide range of determinants of hand dermatitis. The 12-month period prevalence of major hand dermatitis amounted to 29.5% whereas 7.4% had minor dermatitis. Of these workers, 52.1% were sensitized for tulipalin A. Several personal and work-related determinants played a role in the multifactorial aetiology of hand dermatitis. Factors which showed a significant relationship with major hand dermatitis were: female sex, atopic dermatitis, chapped hands and the frequency of washing hands. It may be concluded that the Alstroemeria workers are a population at risk of developing contact dermatitis and it might be useful to carry out an educational campaign to lower the high prevalence.  (+info)

Irritant contact dermatitis due to 1-bromo-3-chloro-5,5-dimethylhydantoin in a hydrotherapy pool. Risk assessments: the need for continuous evidence-based assessments. (4/30946)

A physiotherapist working in hydrotherapy presented to occupational health with irritant contact dermatitis. Subsequent investigation revealed that the likely causative agent was 1-bromo 3-chloro 5,5 dimethylhydantoin which was used to disinfect the hydrotherapy pool. A COSHH risk assessment had been performed which failed to take full account of current knowledge and this agent had been introduced into the workplace. The development of adverse health effects among staff and other pool users lead to a review of this risk assessment and eventually a return to less hazardous chlorine-based disinfection. Had an evidence-based approach been combined with an appropriate COSHH assessment prior to and following changes in the workplace then unnecessary risk to employees would not have occurred.  (+info)

Validation of the Rockall risk scoring system in upper gastrointestinal bleeding. (5/30946)

BACKGROUND: Several scoring systems have been developed to predict the risk of rebleeding or death in patients with upper gastrointestinal bleeding (UGIB). These risk scoring systems have not been validated in a new patient population outside the clinical context of the original study. AIMS: To assess internal and external validity of a simple risk scoring system recently developed by Rockall and coworkers. METHODS: Calibration and discrimination were assessed as measures of validity of the scoring system. Internal validity was assessed using an independent, but similar patient sample studied by Rockall and coworkers, after developing the scoring system (Rockall's validation sample). External validity was assessed using patients admitted to several hospitals in Amsterdam (Vreeburg's validation sample). Calibration was evaluated by a chi2 goodness of fit test, and discrimination was evaluated by calculating the area under the receiver operating characteristic (ROC) curve. RESULTS: Calibration indicated a poor fit in both validation samples for the prediction of rebleeding (p<0.0001, Vreeburg; p=0.007, Rockall), but a better fit for the prediction of mortality in both validation samples (p=0.2, Vreeburg; p=0.3, Rockall). The areas under the ROC curves were rather low in both validation samples for the prediction of rebleeding (0.61, Vreeburg; 0.70, Rockall), but higher for the prediction of mortality (0.73, Vreeburg; 0.81, Rockall). CONCLUSIONS: The risk scoring system developed by Rockall and coworkers is a clinically useful scoring system for stratifying patients with acute UGIB into high and low risk categories for mortality. For the prediction of rebleeding, however, the performance of this scoring system was unsatisfactory.  (+info)

Risk factors for injuries and other health problems sustained in a marathon. (6/30946)

OBJECTIVES: To identify risk factors for injuries and other health problems occurring during or immediately after participation in a marathon. METHODS: A prospective cohort study was undertaken of participants in the 1993 Auckland Citibank marathon. Demographic data, information on running experience, training and injuries, and information on other lifestyle factors were obtained from participants before the race using an interviewer-administered questionnaire. Information on injuries and other health problems sustained during or immediately after the marathon were obtained by a self administered questionnaire. Logistic regression analyses were undertaken to identify significant risk factors for health problems. RESULTS: This study, one of only a few controlled epidemiological studies that have been undertaken of running injuries, has identified a number of risk factors for injuries and other health problems sustained in a marathon. Men were at increased risk of hamstring and calf problems, whereas women were at increased risk of hip problems. Participation in a marathon for the first time, participation in other sports, illness in the two weeks before the marathon, current use of medication, and drinking alcohol once a month or more, were associated with increased self reported risks of problems. While increased training seemed to increase the risk of front thigh and hamstring problems, it may decrease the risk of knee problems. There are significant but complex relations between age and risk of injury or health problem. CONCLUSIONS: This study has identified certain high risk subjects and risk factors for injuries and other health problems sustained in a marathon. In particular, subjects who have recently been unwell or are taking medication should weigh up carefully the pros and cons of participating.  (+info)

Factors influencing tackle injuries in rugby union football. (7/30946)

OBJECTIVES: To assess the influence of selected aspects of lifestyle, personality, and other player related factors on injuries in the tackle. To describe the detailed circumstances in which these tackles occurred. METHODS: A prospective case-control study was undertaken in which the tackling and tackled players ("the cases") involved in a tackle injury were each matched with "control" players who held the same respective playing positions in the opposing teams. A total of 964 rugby matches involving 71 senior clubs drawn from all districts of the Scottish Rugby Union (SRU) were observed by nominated linkmen who administered self report questionnaires to the players identified as cases and controls. Information on lifestyle habits, match preparation, training, and coaching experience was obtained. A validated battery of psychological tests assessed players' trait anger and responses to anger and hostility. The circumstances of the tackles in which injury occurred were recorded by experienced SRU coaching staff in interviews with involved players after the match. RESULTS: A total of 71 tackle injury episodes with correct matching of cases and controls were studied. The following player related factors did not contribute significantly to tackle injuries: alcohol consumption before the match, feeling "below par" through minor illness, the extent of match preparation, previous coaching, or practising tackling. Injured and non-injured players in the tackle did not differ in their disposition toward, or expression of, anger or hostility. Some 85% of tackling players who were injured were three quarters, and 52% of injuries occurred when the tackle came in behind the tackled player or within his peripheral vision. Either the tackling or tackled player was sprinting or running in all of these injury episodes. One third of injuries occurred in differential speed tackles--that is, when one player was travelling much faster than the other at impact. The player with the lower momentum was injured in 80% of these cases. Forceful or crunching tackles resulting in injury mostly occurred head on or within the tackled player's side vision. CONCLUSIONS: Attention should be focused on high speed tackles going in behind the tackled player's line of vision. Comparative information on the circumstances of the vast majority of tackles in which no injury occurs is required before any changes are considered to reduce injuries in the tackle.  (+info)

Rider injury rates and emergency medical services at equestrian events. (8/30946)

BACKGROUND: Horse riding is a hazardous pastime, with a number of studies documenting high rates of injury and death among horse riders in general. This study focuses on the injury experience of cross country event riders, a high risk subset of horse riders. METHOD: Injury data were collected at a series of 35 equestrian events in South Australia from 1990 to 1998. RESULTS: Injury rates were found to be especially high among event riders, with frequent falls, injuries, and even deaths. The highest injury rates were among the riders competing at the highest levels. CONCLUSION: There is a need for skilled emergency medical services at equestrian events.  (+info)

Neoplasm refers to an abnormal growth of cells that can be benign (non-cancerous) or malignant (cancerous). Neoplasms can occur in any part of the body and can affect various organs and tissues. The term "neoplasm" is often used interchangeably with "tumor," but while all tumors are neoplasms, not all neoplasms are tumors.

Types of Neoplasms

There are many different types of neoplasms, including:

1. Carcinomas: These are malignant tumors that arise in the epithelial cells lining organs and glands. Examples include breast cancer, lung cancer, and colon cancer.
2. Sarcomas: These are malignant tumors that arise in connective tissue, such as bone, cartilage, and fat. Examples include osteosarcoma (bone cancer) and soft tissue sarcoma.
3. Lymphomas: These are cancers of the immune system, specifically affecting the lymph nodes and other lymphoid tissues. Examples include Hodgkin lymphoma and non-Hodgkin lymphoma.
4. Leukemias: These are cancers of the blood and bone marrow that affect the white blood cells. Examples include acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL).
5. Melanomas: These are malignant tumors that arise in the pigment-producing cells called melanocytes. Examples include skin melanoma and eye melanoma.

Causes and Risk Factors of Neoplasms

The exact causes of neoplasms are not fully understood, but there are several known risk factors that can increase the likelihood of developing a neoplasm. These include:

1. Genetic predisposition: Some people may be born with genetic mutations that increase their risk of developing certain types of neoplasms.
2. Environmental factors: Exposure to certain environmental toxins, such as radiation and certain chemicals, can increase the risk of developing a neoplasm.
3. Infection: Some neoplasms are caused by viruses or bacteria. For example, human papillomavirus (HPV) is a common cause of cervical cancer.
4. Lifestyle factors: Factors such as smoking, excessive alcohol consumption, and a poor diet can increase the risk of developing certain types of neoplasms.
5. Family history: A person's risk of developing a neoplasm may be higher if they have a family history of the condition.

Signs and Symptoms of Neoplasms

The signs and symptoms of neoplasms can vary depending on the type of cancer and where it is located in the body. Some common signs and symptoms include:

1. Unusual lumps or swelling
2. Pain
3. Fatigue
4. Weight loss
5. Change in bowel or bladder habits
6. Unexplained bleeding
7. Coughing up blood
8. Hoarseness or a persistent cough
9. Changes in appetite or digestion
10. Skin changes, such as a new mole or a change in the size or color of an existing mole.

Diagnosis and Treatment of Neoplasms

The diagnosis of a neoplasm usually involves a combination of physical examination, imaging tests (such as X-rays, CT scans, or MRI scans), and biopsy. A biopsy involves removing a small sample of tissue from the suspected tumor and examining it under a microscope for cancer cells.

The treatment of neoplasms depends on the type, size, location, and stage of the cancer, as well as the patient's overall health. Some common treatments include:

1. Surgery: Removing the tumor and surrounding tissue can be an effective way to treat many types of cancer.
2. Chemotherapy: Using drugs to kill cancer cells can be effective for some types of cancer, especially if the cancer has spread to other parts of the body.
3. Radiation therapy: Using high-energy radiation to kill cancer cells can be effective for some types of cancer, especially if the cancer is located in a specific area of the body.
4. Immunotherapy: Boosting the body's immune system to fight cancer can be an effective treatment for some types of cancer.
5. Targeted therapy: Using drugs or other substances to target specific molecules on cancer cells can be an effective treatment for some types of cancer.

Prevention of Neoplasms

While it is not always possible to prevent neoplasms, there are several steps that can reduce the risk of developing cancer. These include:

1. Avoiding exposure to known carcinogens (such as tobacco smoke and radiation)
2. Maintaining a healthy diet and lifestyle
3. Getting regular exercise
4. Not smoking or using tobacco products
5. Limiting alcohol consumption
6. Getting vaccinated against certain viruses that are associated with cancer (such as human papillomavirus, or HPV)
7. Participating in screening programs for early detection of cancer (such as mammograms for breast cancer and colonoscopies for colon cancer)
8. Avoiding excessive exposure to sunlight and using protective measures such as sunscreen and hats to prevent skin cancer.

It's important to note that not all cancers can be prevented, and some may be caused by factors that are not yet understood or cannot be controlled. However, by taking these steps, individuals can reduce their risk of developing cancer and improve their overall health and well-being.

1. Coronary artery disease: The narrowing or blockage of the coronary arteries, which supply blood to the heart.
2. Heart failure: A condition in which the heart is unable to pump enough blood to meet the body's needs.
3. Arrhythmias: Abnormal heart rhythms that can be too fast, too slow, or irregular.
4. Heart valve disease: Problems with the heart valves that control blood flow through the heart.
5. Heart muscle disease (cardiomyopathy): Disease of the heart muscle that can lead to heart failure.
6. Congenital heart disease: Defects in the heart's structure and function that are present at birth.
7. Peripheral artery disease: The narrowing or blockage of blood vessels that supply oxygen and nutrients to the arms, legs, and other organs.
8. Deep vein thrombosis (DVT): A blood clot that forms in a deep vein, usually in the leg.
9. Pulmonary embolism: A blockage in one of the arteries in the lungs, which can be caused by a blood clot or other debris.
10. Stroke: A condition in which there is a lack of oxygen to the brain due to a blockage or rupture of blood vessels.

Symptoms may include sensitivity, discomfort, visible holes or stains on teeth, bad breath, and difficulty chewing or biting. If left untreated, dental caries can progress and lead to more serious complications such as abscesses, infections, and even tooth loss.

To prevent dental caries, it is essential to maintain good oral hygiene habits, including brushing your teeth at least twice a day with fluoride toothpaste, flossing daily, and using mouthwash regularly. Limiting sugary foods and drinks and visiting a dentist for regular check-ups can also help prevent the disease.

Dental caries is treatable through various methods such as fillings, crowns, root canals, extractions, and preventive measures like fissure sealants and fluoride applications. Early detection and prompt treatment are crucial to prevent further damage and restore oral health.

There are different types of Breast Neoplasms such as:

1. Fibroadenomas: These are benign tumors that are made up of glandular and fibrous tissues. They are usually small and round, with a smooth surface, and can be moved easily under the skin.

2. Cysts: These are fluid-filled sacs that can develop in both breast tissue and milk ducts. They are usually benign and can disappear on their own or be drained surgically.

3. Ductal Carcinoma In Situ (DCIS): This is a precancerous condition where abnormal cells grow inside the milk ducts. If left untreated, it can progress to invasive breast cancer.

4. Invasive Ductal Carcinoma (IDC): This is the most common type of breast cancer and starts in the milk ducts but grows out of them and invades surrounding tissue.

5. Invasive Lobular Carcinoma (ILC): It originates in the milk-producing glands (lobules) and grows out of them, invading nearby tissue.

Breast Neoplasms can cause various symptoms such as a lump or thickening in the breast or underarm area, skin changes like redness or dimpling, change in size or shape of one or both breasts, discharge from the nipple, and changes in the texture or color of the skin.

Treatment options for Breast Neoplasms may include surgery such as lumpectomy, mastectomy, or breast-conserving surgery, radiation therapy which uses high-energy beams to kill cancer cells, chemotherapy using drugs to kill cancer cells, targeted therapy which uses drugs or other substances to identify and attack cancer cells while minimizing harm to normal cells, hormone therapy, immunotherapy, and clinical trials.

It is important to note that not all Breast Neoplasms are cancerous; some are benign (non-cancerous) tumors that do not spread or grow.

Explanation: Genetic predisposition to disease is influenced by multiple factors, including the presence of inherited genetic mutations or variations, environmental factors, and lifestyle choices. The likelihood of developing a particular disease can be increased by inherited genetic mutations that affect the functioning of specific genes or biological pathways. For example, inherited mutations in the BRCA1 and BRCA2 genes increase the risk of developing breast and ovarian cancer.

The expression of genetic predisposition to disease can vary widely, and not all individuals with a genetic predisposition will develop the disease. Additionally, many factors can influence the likelihood of developing a particular disease, such as environmental exposures, lifestyle choices, and other health conditions.

Inheritance patterns: Genetic predisposition to disease can be inherited in an autosomal dominant, autosomal recessive, or multifactorial pattern, depending on the specific disease and the genetic mutations involved. Autosomal dominant inheritance means that a single copy of the mutated gene is enough to cause the disease, while autosomal recessive inheritance requires two copies of the mutated gene. Multifactorial inheritance involves multiple genes and environmental factors contributing to the development of the disease.

Examples of diseases with a known genetic predisposition:

1. Huntington's disease: An autosomal dominant disorder caused by an expansion of a CAG repeat in the Huntingtin gene, leading to progressive neurodegeneration and cognitive decline.
2. Cystic fibrosis: An autosomal recessive disorder caused by mutations in the CFTR gene, leading to respiratory and digestive problems.
3. BRCA1/2-related breast and ovarian cancer: An inherited increased risk of developing breast and ovarian cancer due to mutations in the BRCA1 or BRCA2 genes.
4. Sickle cell anemia: An autosomal recessive disorder caused by a point mutation in the HBB gene, leading to defective hemoglobin production and red blood cell sickling.
5. Type 1 diabetes: An autoimmune disease caused by a combination of genetic and environmental factors, including multiple genes in the HLA complex.

Understanding the genetic basis of disease can help with early detection, prevention, and treatment. For example, genetic testing can identify individuals who are at risk for certain diseases, allowing for earlier intervention and preventive measures. Additionally, understanding the genetic basis of a disease can inform the development of targeted therapies and personalized medicine."


1. Asbestosis: a lung disease caused by inhaling asbestos fibers.
2. Carpal tunnel syndrome: a nerve disorder caused by repetitive motion and pressure on the wrist.
3. Mesothelioma: a type of cancer caused by exposure to asbestos.
4. Pneumoconiosis: a lung disease caused by inhaling dust from mining or other heavy industries.
5. Repetitive strain injuries: injuries caused by repetitive motions, such as typing or using vibrating tools.
6. Skin conditions: such as skin irritation and dermatitis caused by exposure to chemicals or other substances in the workplace.
7. Hearing loss: caused by loud noises in the workplace.
8. Back injuries: caused by lifting, bending, or twisting.
9. Respiratory problems: such as asthma and other breathing difficulties caused by exposure to chemicals or dust in the workplace.
10. Cancer: caused by exposure to carcinogens such as radiation, certain chemicals, or heavy metals in the workplace.

Occupational diseases can be difficult to diagnose and treat, as they often develop gradually over time and may not be immediately attributed to the work environment. In some cases, these diseases may not appear until years after exposure has ended. It is important for workers to be aware of the potential health risks associated with their job and take steps to protect themselves, such as wearing protective gear, following safety protocols, and seeking regular medical check-ups. Employers also have a responsibility to provide a safe work environment and follow strict regulations to prevent the spread of occupational diseases.

There are several factors that can contribute to the development of pressure ulcers, including:

1. Pressure: Prolonged pressure on a specific area of the body can cause damage to the skin and underlying tissue.
2. Shear: Movement or sliding of the body against a surface can also contribute to the development of pressure ulcers.
3. Friction: Rubbing or friction against a surface can damage the skin and increase the risk of pressure ulcers.
4. Moisture: Skin that is wet or moist is more susceptible to pressure ulcers.
5. Incontinence: Lack of bladder or bowel control can lead to prolonged exposure of the skin to urine or stool, increasing the risk of pressure ulcers.
6. Immobility: People who are unable to move or change positions frequently are at higher risk for pressure ulcers.
7. Malnutrition: A diet that is deficient in essential nutrients can impair the body's ability to heal and increase the risk of pressure ulcers.
8. Smoking: Smoking can damage blood vessels and reduce blood flow to the skin, increasing the risk of pressure ulcers.
9. Diabetes: People with diabetes are at higher risk for pressure ulcers due to nerve damage and poor circulation.
10. Age: The elderly are more susceptible to pressure ulcers due to decreased mobility, decreased blood flow, and thinning skin.

Pressure ulcers can be classified into several different stages based on their severity and the extent of tissue damage. Treatment for pressure ulcers typically involves addressing the underlying cause and providing wound care to promote healing. This may include changing positions frequently, using support surfaces to reduce pressure, and managing incontinence and moisture. In severe cases, surgery may be necessary to clean and close the wound.

Prevention is key in avoiding pressure ulcers. Strategies for prevention include:

1. Turning and repositioning frequently to redistribute pressure.
2. Using support surfaces that are designed to reduce pressure on the skin, such as foam mattresses or specialized cushions.
3. Maintaining good hygiene and keeping the skin clean and dry.
4. Managing incontinence and moisture to prevent skin irritation and breakdown.
5. Monitoring nutrition and hydration to ensure adequate intake.
6. Encouraging mobility and physical activity to improve circulation and reduce immobility.
7. Avoiding tight clothing and bedding that can constrict the skin.
8. Providing proper skin care and using topical creams or ointments to prevent skin breakdown.

In conclusion, pressure ulcers are a common complication of immobility and can lead to significant morbidity and mortality. Understanding the causes and risk factors for pressure ulcers is essential in preventing and managing these wounds. Proper assessment, prevention, and treatment strategies can improve outcomes and reduce the burden of pressure ulcers on patients and healthcare systems.

Osteoporotic fractures can occur in any bone, but they most commonly affect the spine, hips, and wrists. The risk of developing osteoporotic fractures increases with age, and certain factors such as family history, lifestyle habits (e.g., smoking, alcohol consumption), and medical conditions (e.g., rheumatoid arthritis) can also contribute to the development of osteoporosis and associated fractures.

There are several types of osteoporotic fractures, including:

1. Vertebral compression fractures: These occur when the vertebrae in the spine collapse due to weakened bone density, causing back pain, loss of height, and a stooped posture.
2. Hip fractures: These are breaks in the thigh bone (femur) or pelvis that can be caused by falls or other injuries, and can lead to complications such as blood clots, pneumonia, and surgical intervention.
3. Wrist fractures: These occur when the bones of the wrist break due to a fall or other injury, and can cause pain, swelling, and limited mobility.
4. Fractures of the ribs and long bones: These are less common but can still cause significant pain and disability.

The diagnosis of osteoporotic fractures is typically made through imaging tests such as X-rays, CT scans, or MRIs, and may also involve blood tests to assess bone mineral density (BMD) and other factors. Treatment for osteoporotic fractures typically involves a combination of medications, lifestyle modifications, and surgical interventions to help restore bone strength and prevent further fractures.

There are several types of drug-related side effects and adverse reactions, including:

1. Common side effects: These are side effects that are commonly experienced by patients taking a particular medication. Examples include nausea, dizziness, and fatigue.
2. Serious side effects: These are side effects that can be severe or life-threatening. Examples include allergic reactions, liver damage, and bone marrow suppression.
3. Adverse events: These are any unwanted or harmful effects that occur during the use of a medication, including side effects and other clinical events such as infections or injuries.
4. Drug interactions: These are interactions between two or more drugs that can cause harmful side effects or reduce the effectiveness of one or both drugs.
5. Side effects caused by drug abuse: These are side effects that occur when a medication is taken in larger-than-recommended doses or in a manner other than as directed. Examples include hallucinations, seizures, and overdose.

It's important to note that not all side effects and adverse reactions are caused by the drug itself. Some may be due to other factors, such as underlying medical conditions, other medications being taken, or environmental factors.

To identify and manage drug-related side effects and adverse reactions, healthcare providers will typically ask patients about any symptoms they are experiencing, perform physical exams, and review the patient's medical history and medication list. In some cases, additional tests may be ordered to help diagnose and manage the problem.

Overall, it's important for patients taking medications to be aware of the potential for side effects and adverse reactions, and to report any symptoms or concerns to their healthcare provider promptly. This can help ensure that any issues are identified and addressed early, minimizing the risk of harm and ensuring that the patient receives the best possible care.

Coronary disease is often caused by a combination of genetic and lifestyle factors, such as high blood pressure, high cholesterol levels, smoking, obesity, and a lack of physical activity. It can also be triggered by other medical conditions, such as diabetes and kidney disease.

The symptoms of coronary disease can vary depending on the severity of the condition, but may include:

* Chest pain or discomfort (angina)
* Shortness of breath
* Fatigue
* Swelling of the legs and feet
* Pain in the arms and back

Coronary disease is typically diagnosed through a combination of physical examination, medical history, and diagnostic tests such as electrocardiograms (ECGs), stress tests, and cardiac imaging. Treatment for coronary disease may include lifestyle changes, medications to control symptoms, and surgical procedures such as angioplasty or bypass surgery to improve blood flow to the heart.

Preventative measures for coronary disease include:

* Maintaining a healthy diet and exercise routine
* Quitting smoking and limiting alcohol consumption
* Managing high blood pressure, high cholesterol levels, and other underlying medical conditions
* Reducing stress through relaxation techniques or therapy.

The symptoms of dermatitis, allergic contact can vary depending on the severity of the reaction, but may include:

* Redness and swelling of the affected area
* Itching, burning, or stinging sensations
* Small blisters or hives
* Thickening or scaling of the skin
* Crusting or oozing of fluid

Dermatitis, allergic contact can be caused by a variety of substances, including:

* Metals, such as nickel, chrome, and mercury
* Plastics, such as latex and polyethylene
* Certain chemicals, such as perfumes, dyes, and preservatives
* Plant extracts, such as poison ivy or poison oak
* Insect bites or stings

The diagnosis of dermatitis, allergic contact is typically made through a combination of physical examination, medical history, and patch testing. Patch testing involves applying small amounts of potential allergens to the skin and observing for any signs of an allergic reaction over a period of time.

Treatment for dermatitis, allergic contact typically focuses on removing the allergen from the affected area and providing relief from symptoms. This may include:

* Avoiding exposure to the allergen
* Applying topical creams or ointments to reduce inflammation and itching
* Taking oral medications, such as antihistamines or corticosteroids, to reduce symptoms
* In severe cases, hospitalization may be necessary to manage the reaction.

Preventative measures for dermatitis, allergic contact include:

* Avoiding exposure to potential allergens
* Wearing protective clothing or gloves when handling suspected allergens
* Using hypoallergenic products and avoiding fragrances and dyes
* Performing patch testing before introducing new substances into the environment.

It is important to seek medical attention if symptoms persist or worsen over time, as dermatitis, allergic contact can lead to complications such as infection or scarring. Early diagnosis and treatment can help prevent these complications and improve outcomes for patients with this condition.

Open fracture: The bone breaks through the skin, exposing the bone to the outside environment.

Closed fracture: The bone breaks, but does not penetrate the skin.

Comminuted fracture: The bone is broken into many pieces.

Hairline fracture: A thin crack in the bone that does not fully break it.

Non-displaced fracture: The bone is broken, but remains in its normal position.

Displaced fracture: The bone is broken and out of its normal position.

Stress fracture: A small crack in the bone caused by repetitive stress or overuse.

Some common types of mental disorders include:

1. Anxiety disorders: These conditions cause excessive worry, fear, or anxiety that interferes with daily life. Examples include generalized anxiety disorder, panic disorder, and social anxiety disorder.
2. Mood disorders: These conditions affect a person's mood, causing feelings of sadness, hopelessness, or anger that persist for weeks or months. Examples include depression, bipolar disorder, and seasonal affective disorder.
3. Personality disorders: These conditions involve patterns of thought and behavior that deviate from the norm of the average person. Examples include borderline personality disorder, narcissistic personality disorder, and antisocial personality disorder.
4. Psychotic disorders: These conditions cause a person to lose touch with reality, resulting in delusions, hallucinations, or disorganized thinking. Examples include schizophrenia, schizoaffective disorder, and brief psychotic disorder.
5. Trauma and stressor-related disorders: These conditions develop after a person experiences a traumatic event, such as post-traumatic stress disorder (PTSD).
6. Dissociative disorders: These conditions involve a disconnection or separation from one's body, thoughts, or emotions. Examples include dissociative identity disorder (formerly known as multiple personality disorder) and depersonalization disorder.
7. Neurodevelopmental disorders: These conditions affect the development of the brain and nervous system, leading to symptoms such as difficulty with social interaction, communication, and repetitive behaviors. Examples include autism spectrum disorder, attention deficit hyperactivity disorder (ADHD), and Rett syndrome.

Mental disorders can be diagnosed by a mental health professional using the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), which provides criteria for each condition. Treatment typically involves a combination of medication and therapy, such as cognitive-behavioral therapy or psychodynamic therapy, depending on the specific disorder and individual needs.

The burden of chronic diseases is significant, with over 70% of deaths worldwide attributed to them, according to the World Health Organization (WHO). In addition to the physical and emotional toll they take on individuals and their families, chronic diseases also pose a significant economic burden, accounting for a large proportion of healthcare expenditure.

In this article, we will explore the definition and impact of chronic diseases, as well as strategies for managing and living with them. We will also discuss the importance of early detection and prevention, as well as the role of healthcare providers in addressing the needs of individuals with chronic diseases.

What is a Chronic Disease?

A chronic disease is a condition that lasts for an extended period of time, often affecting daily life and activities. Unlike acute diseases, which have a specific beginning and end, chronic diseases are long-term and persistent. Examples of chronic diseases include:

1. Diabetes
2. Heart disease
3. Arthritis
4. Asthma
5. Cancer
6. Chronic obstructive pulmonary disease (COPD)
7. Chronic kidney disease (CKD)
8. Hypertension
9. Osteoporosis
10. Stroke

Impact of Chronic Diseases

The burden of chronic diseases is significant, with over 70% of deaths worldwide attributed to them, according to the WHO. In addition to the physical and emotional toll they take on individuals and their families, chronic diseases also pose a significant economic burden, accounting for a large proportion of healthcare expenditure.

Chronic diseases can also have a significant impact on an individual's quality of life, limiting their ability to participate in activities they enjoy and affecting their relationships with family and friends. Moreover, the financial burden of chronic diseases can lead to poverty and reduce economic productivity, thus having a broader societal impact.

Addressing Chronic Diseases

Given the significant burden of chronic diseases, it is essential that we address them effectively. This requires a multi-faceted approach that includes:

1. Lifestyle modifications: Encouraging healthy behaviors such as regular physical activity, a balanced diet, and smoking cessation can help prevent and manage chronic diseases.
2. Early detection and diagnosis: Identifying risk factors and detecting diseases early can help prevent or delay their progression.
3. Medication management: Effective medication management is crucial for controlling symptoms and slowing disease progression.
4. Multi-disciplinary care: Collaboration between healthcare providers, patients, and families is essential for managing chronic diseases.
5. Health promotion and disease prevention: Educating individuals about the risks of chronic diseases and promoting healthy behaviors can help prevent their onset.
6. Addressing social determinants of health: Social determinants such as poverty, education, and employment can have a significant impact on health outcomes. Addressing these factors is essential for reducing health disparities and improving overall health.
7. Investing in healthcare infrastructure: Investing in healthcare infrastructure, technology, and research is necessary to improve disease detection, diagnosis, and treatment.
8. Encouraging policy change: Policy changes can help create supportive environments for healthy behaviors and reduce the burden of chronic diseases.
9. Increasing public awareness: Raising public awareness about the risks and consequences of chronic diseases can help individuals make informed decisions about their health.
10. Providing support for caregivers: Chronic diseases can have a significant impact on family members and caregivers, so providing them with support is essential for improving overall health outcomes.

Conclusion

Chronic diseases are a major public health burden that affect millions of people worldwide. Addressing these diseases requires a multi-faceted approach that includes lifestyle changes, addressing social determinants of health, investing in healthcare infrastructure, encouraging policy change, increasing public awareness, and providing support for caregivers. By taking a comprehensive approach to chronic disease prevention and management, we can improve the health and well-being of individuals and communities worldwide.

1. Infection: Bacterial or viral infections can develop after surgery, potentially leading to sepsis or organ failure.
2. Adhesions: Scar tissue can form during the healing process, which can cause bowel obstruction, chronic pain, or other complications.
3. Wound complications: Incisional hernias, wound dehiscence (separation of the wound edges), and wound infections can occur.
4. Respiratory problems: Pneumonia, respiratory failure, and atelectasis (collapsed lung) can develop after surgery, particularly in older adults or those with pre-existing respiratory conditions.
5. Cardiovascular complications: Myocardial infarction (heart attack), cardiac arrhythmias, and cardiac failure can occur after surgery, especially in high-risk patients.
6. Renal (kidney) problems: Acute kidney injury or chronic kidney disease can develop postoperatively, particularly in patients with pre-existing renal impairment.
7. Neurological complications: Stroke, seizures, and neuropraxia (nerve damage) can occur after surgery, especially in patients with pre-existing neurological conditions.
8. Pulmonary embolism: Blood clots can form in the legs or lungs after surgery, potentially causing pulmonary embolism.
9. Anesthesia-related complications: Respiratory and cardiac complications can occur during anesthesia, including respiratory and cardiac arrest.
10. delayed healing: Wound healing may be delayed or impaired after surgery, particularly in patients with pre-existing medical conditions.

It is important for patients to be aware of these potential complications and to discuss any concerns with their surgeon and healthcare team before undergoing surgery.

Disease progression can be classified into several types based on the pattern of worsening:

1. Chronic progressive disease: In this type, the disease worsens steadily over time, with a gradual increase in symptoms and decline in function. Examples include rheumatoid arthritis, osteoarthritis, and Parkinson's disease.
2. Acute progressive disease: This type of disease worsens rapidly over a short period, often followed by periods of stability. Examples include sepsis, acute myocardial infarction (heart attack), and stroke.
3. Cyclical disease: In this type, the disease follows a cycle of worsening and improvement, with periodic exacerbations and remissions. Examples include multiple sclerosis, lupus, and rheumatoid arthritis.
4. Recurrent disease: This type is characterized by episodes of worsening followed by periods of recovery. Examples include migraine headaches, asthma, and appendicitis.
5. Catastrophic disease: In this type, the disease progresses rapidly and unpredictably, with a poor prognosis. Examples include cancer, AIDS, and organ failure.

Disease progression can be influenced by various factors, including:

1. Genetics: Some diseases are inherited and may have a predetermined course of progression.
2. Lifestyle: Factors such as smoking, lack of exercise, and poor diet can contribute to disease progression.
3. Environmental factors: Exposure to toxins, allergens, and other environmental stressors can influence disease progression.
4. Medical treatment: The effectiveness of medical treatment can impact disease progression, either by slowing or halting the disease process or by causing unintended side effects.
5. Co-morbidities: The presence of multiple diseases or conditions can interact and affect each other's progression.

Understanding the type and factors influencing disease progression is essential for developing effective treatment plans and improving patient outcomes.

Deep Vein Thrombosis (DVT): DVT occurs when a blood clot forms in the deep veins of the body, usually in the legs. This can cause swelling, pain, and warmth in the affected area.

Pulmonary Embolism (PE): PE occurs when a blood clot from the deep veins of the body travels to the lungs, causing shortness of breath, chest pain, and coughing up bloody mucus.

The risk factors for VTE include:

* Prolonged immobility (e.g., long-distance travel or bed rest)
* Injury or surgery
* Age > 60 years
* Family history of VTE
* Cancer and its treatment
* Hormone replacement therapy or birth control pills
* Inherited blood-clotting disorders
* Inflammatory bowel disease

Prevention methods include:

* Moving around regularly during long-distance travel or bed rest
* Avoiding crossing your legs or ankles, which can restrict blood flow
* Wearing compression stockings during travel or when advised by a healthcare professional
* Elevating the affected leg when sitting or lying down
* Taking blood-thinning medication as prescribed by a healthcare professional

Early diagnosis and treatment of VTE can help prevent serious complications such as PE. Treatment options include anticoagulant medications, thrombolysis (dissolving the clot), and filtration devices.

The buildup of plaque in the coronary arteries is often caused by high levels of low-density lipoprotein (LDL) cholesterol, smoking, high blood pressure, diabetes, and a family history of heart disease. The plaque can also rupture, causing a blood clot to form, which can completely block the flow of blood to the heart muscle, leading to a heart attack.

CAD is the most common type of heart disease and is often asymptomatic until a serious event occurs. Risk factors for CAD include:

* Age (men over 45 and women over 55)
* Gender (men are at greater risk than women, but women are more likely to die from CAD)
* Family history of heart disease
* High blood pressure
* High cholesterol
* Diabetes
* Smoking
* Obesity
* Lack of exercise

Diagnosis of CAD typically involves a physical exam, medical history, and results of diagnostic tests such as:

* Electrocardiogram (ECG or EKG)
* Stress test
* Echocardiogram
* Coronary angiography

Treatment for CAD may include lifestyle changes such as a healthy diet, regular exercise, stress management, and quitting smoking. Medications such as beta blockers, ACE inhibitors, and statins may also be prescribed to manage symptoms and slow the progression of the disease. In severe cases, surgical intervention such as coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) may be necessary.

Prevention of CAD includes managing risk factors such as high blood pressure, high cholesterol, and diabetes, quitting smoking, maintaining a healthy weight, and getting regular exercise. Early detection and treatment of CAD can help to reduce the risk of complications and improve quality of life for those affected by the disease.

1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.

2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.

3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.

4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.

5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.

6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.

7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.

8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.

9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.

10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.

There are many different types of heart diseases, including:

1. Coronary artery disease: The buildup of plaque in the coronary arteries, which supply blood to the heart muscle, leading to chest pain or a heart attack.
2. Heart failure: When the heart is unable to pump enough blood to meet the body's needs, leading to fatigue, shortness of breath, and swelling in the legs.
3. Arrhythmias: Abnormal heart rhythms, such as atrial fibrillation or ventricular tachycardia, which can cause palpitations, dizziness, and shortness of breath.
4. Heart valve disease: Problems with the heart valves, which can lead to blood leaking back into the chambers or not being pumped effectively.
5. Cardiomyopathy: Disease of the heart muscle, which can lead to weakened heart function and heart failure.
6. Heart murmurs: Abnormal sounds heard during a heartbeat, which can be caused by defects in the heart valves or abnormal blood flow.
7. Congenital heart disease: Heart defects present at birth, such as holes in the heart or abnormal blood vessels.
8. Myocardial infarction (heart attack): Damage to the heart muscle due to a lack of oxygen, often caused by a blockage in a coronary artery.
9. Cardiac tamponade: Fluid accumulation around the heart, which can cause compression of the heart and lead to cardiac arrest.
10. Endocarditis: Infection of the inner lining of the heart, which can cause fever, fatigue, and heart valve damage.

Heart diseases can be diagnosed through various tests such as electrocardiogram (ECG), echocardiogram, stress test, and blood tests. Treatment options depend on the specific condition and may include lifestyle changes, medication, surgery, or a combination of these.

1. Ischemic stroke: This is the most common type of stroke, accounting for about 87% of all strokes. It occurs when a blood vessel in the brain becomes blocked, reducing blood flow to the brain.
2. Hemorrhagic stroke: This type of stroke occurs when a blood vessel in the brain ruptures, causing bleeding in the brain. High blood pressure, aneurysms, and blood vessel malformations can all cause hemorrhagic strokes.
3. Transient ischemic attack (TIA): Also known as a "mini-stroke," a TIA is a temporary interruption of blood flow to the brain that lasts for a short period of time, usually less than 24 hours. TIAs are often a warning sign for a future stroke and should be taken seriously.

Stroke can cause a wide range of symptoms depending on the location and severity of the damage to the brain. Some common symptoms include:

* Weakness or numbness in the face, arm, or leg
* Difficulty speaking or understanding speech
* Sudden vision loss or double vision
* Dizziness, loss of balance, or sudden falls
* Severe headache
* Confusion, disorientation, or difficulty with memory

Stroke is a leading cause of long-term disability and can have a significant impact on the quality of life for survivors. However, with prompt medical treatment and rehabilitation, many people are able to recover some or all of their lost functions and lead active lives.

The medical community has made significant progress in understanding stroke and developing effective treatments. Some of the most important advances include:

* Development of clot-busting drugs and mechanical thrombectomy devices to treat ischemic strokes
* Improved imaging techniques, such as CT and MRI scans, to diagnose stroke and determine its cause
* Advances in surgical techniques for hemorrhagic stroke
* Development of new medications to prevent blood clots and reduce the risk of stroke

Despite these advances, stroke remains a significant public health problem. According to the American Heart Association, stroke is the fifth leading cause of death in the United States and the leading cause of long-term disability. In 2017, there were over 795,000 strokes in the United States alone.

There are several risk factors for stroke that can be controlled or modified. These include:

* High blood pressure
* Diabetes mellitus
* High cholesterol levels
* Smoking
* Obesity
* Lack of physical activity
* Poor diet

In addition to these modifiable risk factors, there are also several non-modifiable risk factors for stroke, such as age (stroke risk increases with age), family history of stroke, and previous stroke or transient ischemic attack (TIA).

The medical community has made significant progress in understanding the causes and risk factors for stroke, as well as developing effective treatments and prevention strategies. However, more research is needed to improve outcomes for stroke survivors and reduce the overall burden of this disease.

The presence of chromosome-defective micronuclei in cells can be an indication of genetic damage and may be used as a diagnostic marker for certain diseases or conditions, such as cancer or exposure to toxic substances. The frequency and distribution of these structures within a cell population can also provide information about the type and severity of genetic damage present.

In contrast to other types of micronuclei, which are typically smaller and less complex, chromosome-defective micronuclei are larger and more irregular in shape, and may contain fragmented or abnormal chromatin material. They can also be distinguished from other types of micronuclei by their specific staining properties and the presence of certain structural features, such as the presence of nucleoli or the absence of a membrane boundary.

Overall, the study of chromosome-defective micronuclei is an important tool for understanding the mechanisms of genetic damage and disease, and may have practical applications in fields such as cancer diagnosis and environmental health assessment.

There are several types of lung neoplasms, including:

1. Adenocarcinoma: This is the most common type of lung cancer, accounting for approximately 40% of all lung cancers. It is a malignant tumor that originates in the glands of the respiratory tract and can be found in any part of the lung.
2. Squamous cell carcinoma: This type of lung cancer accounts for approximately 25% of all lung cancers and is more common in men than women. It is a malignant tumor that originates in the squamous cells lining the airways of the lungs.
3. Small cell lung cancer (SCLC): This is a highly aggressive form of lung cancer that accounts for approximately 15% of all lung cancers. It is often found in the central parts of the lungs and can spread quickly to other parts of the body.
4. Large cell carcinoma: This is a rare type of lung cancer that accounts for only about 5% of all lung cancers. It is a malignant tumor that originates in the large cells of the respiratory tract and can be found in any part of the lung.
5. Bronchioalveolar carcinoma (BAC): This is a rare type of lung cancer that originates in the cells lining the airways and alveoli of the lungs. It is more common in women than men and tends to affect older individuals.
6. Lymphangioleiomyomatosis (LAM): This is a rare, progressive, and often fatal lung disease that primarily affects women of childbearing age. It is characterized by the growth of smooth muscle-like cells in the lungs and can lead to cysts, lung collapse, and respiratory failure.
7. Hamartoma: This is a benign tumor that originates in the tissue of the lungs and is usually found in children. It is characterized by an overgrowth of normal lung tissue and can be treated with surgery.
8. Secondary lung cancer: This type of cancer occurs when cancer cells from another part of the body spread to the lungs through the bloodstream or lymphatic system. It is more common in people who have a history of smoking or exposure to other carcinogens.
9. Metastatic cancer: This type of cancer occurs when cancer cells from another part of the body spread to the lungs through the bloodstream or lymphatic system. It is more common in people who have a history of smoking or exposure to other carcinogens.
10. Mesothelioma: This is a rare and aggressive form of cancer that originates in the lining of the lungs or abdomen. It is caused by asbestos exposure and can be treated with surgery, chemotherapy, and radiation therapy.

Lung diseases can also be classified based on their cause, such as:

1. Infectious diseases: These are caused by bacteria, viruses, or other microorganisms and can include pneumonia, tuberculosis, and bronchitis.
2. Autoimmune diseases: These are caused by an overactive immune system and can include conditions such as sarcoidosis and idiopathic pulmonary fibrosis.
3. Genetic diseases: These are caused by inherited mutations in genes that affect the lungs and can include cystic fibrosis and primary ciliary dyskinesia.
4. Environmental diseases: These are caused by exposure to harmful substances such as tobacco smoke, air pollution, and asbestos.
5. Radiological diseases: These are caused by exposure to ionizing radiation and can include conditions such as radiographic breast cancer and lung cancer.
6. Vascular diseases: These are caused by problems with the blood vessels in the lungs and can include conditions such as pulmonary embolism and pulmonary hypertension.
7. Tumors: These can be benign or malignant and can include conditions such as lung metastases and lung cancer.
8. Trauma: This can include injuries to the chest or lungs caused by accidents or other forms of trauma.
9. Congenital diseases: These are present at birth and can include conditions such as bronchopulmonary foregut malformations and congenital cystic adenomatoid malformation.

Each type of lung disease has its own set of symptoms, diagnosis, and treatment options. It is important to seek medical attention if you experience any persistent or severe respiratory symptoms, as early diagnosis and treatment can improve outcomes and quality of life.

Examples of Nervous System Diseases include:

1. Alzheimer's disease: A progressive neurological disorder that affects memory and cognitive function.
2. Parkinson's disease: A degenerative disorder that affects movement, balance and coordination.
3. Multiple sclerosis: An autoimmune disease that affects the protective covering of nerve fibers.
4. Stroke: A condition where blood flow to the brain is interrupted, leading to brain cell death.
5. Brain tumors: Abnormal growth of tissue in the brain.
6. Neuropathy: Damage to peripheral nerves that can cause pain, numbness and weakness in hands and feet.
7. Epilepsy: A disorder characterized by recurrent seizures.
8. Motor neuron disease: Diseases that affect the nerve cells responsible for controlling voluntary muscle movement.
9. Chronic pain syndrome: Persistent pain that lasts more than 3 months.
10. Neurodevelopmental disorders: Conditions such as autism, ADHD and learning disabilities that affect the development of the brain and nervous system.

These diseases can be caused by a variety of factors such as genetics, infections, injuries, toxins and ageing. Treatment options for Nervous System Diseases range from medications, surgery, rehabilitation therapy to lifestyle changes.

Recurrence can also refer to the re-emergence of symptoms in a previously treated condition, such as a chronic pain condition that returns after a period of remission.

In medical research, recurrence is often studied to understand the underlying causes of disease progression and to develop new treatments and interventions to prevent or delay its return.

There are different types of myocardial infarctions, including:

1. ST-segment elevation myocardial infarction (STEMI): This is the most severe type of heart attack, where a large area of the heart muscle is damaged. It is characterized by a specific pattern on an electrocardiogram (ECG) called the ST segment.
2. Non-ST-segment elevation myocardial infarction (NSTEMI): This type of heart attack is less severe than STEMI, and the damage to the heart muscle may not be as extensive. It is characterized by a smaller area of damage or a different pattern on an ECG.
3. Incomplete myocardial infarction: This type of heart attack is when there is some damage to the heart muscle but not a complete blockage of blood flow.
4. Collateral circulation myocardial infarction: This type of heart attack occurs when there are existing collateral vessels that bypass the blocked coronary artery, which reduces the amount of damage to the heart muscle.

Symptoms of a myocardial infarction can include chest pain or discomfort, shortness of breath, lightheadedness, and fatigue. These symptoms may be accompanied by anxiety, fear, and a sense of impending doom. In some cases, there may be no noticeable symptoms at all.

Diagnosis of myocardial infarction is typically made based on a combination of physical examination findings, medical history, and diagnostic tests such as an electrocardiogram (ECG), cardiac enzyme tests, and imaging studies like echocardiography or cardiac magnetic resonance imaging.

Treatment of myocardial infarction usually involves medications to relieve pain, reduce the amount of work the heart has to do, and prevent further damage to the heart muscle. These may include aspirin, beta blockers, ACE inhibitors or angiotensin receptor blockers, and statins. In some cases, a procedure such as angioplasty or coronary artery bypass surgery may be necessary to restore blood flow to the affected area.

Prevention of myocardial infarction involves managing risk factors such as high blood pressure, high cholesterol, smoking, diabetes, and obesity. This can include lifestyle changes such as a healthy diet, regular exercise, and stress reduction, as well as medications to control these conditions. Early detection and treatment of heart disease can help prevent myocardial infarction from occurring in the first place.

Types of Cognition Disorders: There are several types of cognitive disorders that affect different aspects of cognitive functioning. Some common types include:

1. Attention Deficit Hyperactivity Disorder (ADHD): Characterized by symptoms of inattention, hyperactivity, and impulsivity.
2. Traumatic Brain Injury (TBI): Caused by a blow or jolt to the head that disrupts brain function, resulting in cognitive, emotional, and behavioral changes.
3. Alzheimer's Disease: A progressive neurodegenerative disorder characterized by memory loss, confusion, and difficulty with communication.
4. Stroke: A condition where blood flow to the brain is interrupted, leading to cognitive impairment and other symptoms.
5. Parkinson's Disease: A neurodegenerative disorder that affects movement, balance, and cognition.
6. Huntington's Disease: An inherited disorder that causes progressive damage to the brain, leading to cognitive decline and other symptoms.
7. Frontotemporal Dementia (FTD): A group of neurodegenerative disorders characterized by changes in personality, behavior, and language.
8. Post-Traumatic Stress Disorder (PTSD): A condition that develops after a traumatic event, characterized by symptoms such as anxiety, avoidance, and hypervigilance.
9. Mild Cognitive Impairment (MCI): A condition characterized by memory loss and other cognitive symptoms that are more severe than normal age-related changes but not severe enough to interfere with daily life.

Causes and Risk Factors: The causes of cognition disorders can vary depending on the specific disorder, but some common risk factors include:

1. Genetics: Many cognitive disorders have a genetic component, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.
2. Age: As people age, their risk of developing cognitive disorders increases, such as Alzheimer's disease, vascular dementia, and frontotemporal dementia.
3. Lifestyle factors: Factors such as physical inactivity, smoking, and poor diet can increase the risk of cognitive decline and dementia.
4. Traumatic brain injury: A severe blow to the head or a traumatic brain injury can increase the risk of developing cognitive disorders, such as chronic traumatic encephalopathy (CTE).
5. Infections: Certain infections, such as meningitis and encephalitis, can cause cognitive disorders if they damage the brain tissue.
6. Stroke or other cardiovascular conditions: A stroke or other cardiovascular conditions can cause cognitive disorders by damaging the blood vessels in the brain.
7. Chronic substance abuse: Long-term use of drugs or alcohol can damage the brain and increase the risk of cognitive disorders, such as dementia.
8. Sleep disorders: Sleep disorders, such as sleep apnea, can increase the risk of cognitive disorders, such as dementia.
9. Depression and anxiety: Mental health conditions, such as depression and anxiety, can increase the risk of cognitive decline and dementia.
10. Environmental factors: Exposure to certain environmental toxins, such as pesticides and heavy metals, has been linked to an increased risk of cognitive disorders.

It's important to note that not everyone with these risk factors will develop a cognitive disorder, and some people without any known risk factors can still develop a cognitive disorder. If you have concerns about your cognitive health, it's important to speak with a healthcare professional for proper evaluation and diagnosis.

There are several types of osteoporosis, including:

1. Postmenopausal osteoporosis: This type of osteoporosis is caused by hormonal changes that occur during menopause. It is the most common form of osteoporosis and affects women more than men.
2. Senile osteoporosis: This type of osteoporosis is caused by aging and is the most common form of osteoporosis in older adults.
3. Juvenile osteoporosis: This type of osteoporosis affects children and young adults and can be caused by a variety of genetic disorders or other medical conditions.
4. secondary osteoporosis: This type of osteoporosis is caused by other medical conditions, such as rheumatoid arthritis, Crohn's disease, or ulcerative colitis.

The symptoms of osteoporosis can be subtle and may not appear until a fracture has occurred. They can include:

1. Back pain or loss of height
2. A stooped posture
3. Fractures, especially in the spine, hips, or wrists
4. Loss of bone density, as determined by a bone density test

The diagnosis of osteoporosis is typically made through a combination of physical examination, medical history, and imaging tests, such as X-rays or bone density tests. Treatment for osteoporosis can include medications, such as bisphosphonates, hormone therapy, or rANK ligand inhibitors, as well as lifestyle changes, such as regular exercise and a balanced diet.

Preventing osteoporosis is important, as it can help to reduce the risk of fractures and other complications. To prevent osteoporosis, individuals can:

1. Get enough calcium and vitamin D throughout their lives
2. Exercise regularly, especially weight-bearing activities such as walking or running
3. Avoid smoking and excessive alcohol consumption
4. Maintain a healthy body weight
5. Consider taking medications to prevent osteoporosis, such as bisphosphonates, if recommended by a healthcare provider.

Example sentences:

1. The patient developed a radiation-induced neoplasm in their chest after undergoing radiation therapy for breast cancer.
2. The risk of radiation-induced neoplasms increases with higher doses of radiation exposure, making it crucial to minimize exposure during medical procedures.
3. The oncologist monitored the patient's health closely after their radiation therapy to detect any signs of radiation-induced neoplasms.

Zoonoses (zoonosis) refers to infectious diseases that can be transmitted between animals and humans. These diseases are caused by a variety of pathogens, including bacteria, viruses, parasites, and fungi, and can be spread through contact with infected animals or contaminated animal products.

Examples of Zoonoses

Some common examples of zoonoses include:

1. Rabies: a viral infection that can be transmitted to humans through the bite of an infected animal, typically dogs, bats, or raccoons.
2. Lyme disease: a bacterial infection caused by Borrelia burgdorferi, which is spread to humans through the bite of an infected blacklegged tick (Ixodes scapularis).
3. Toxoplasmosis: a parasitic infection caused by Toxoplasma gondii, which can be transmitted to humans through contact with contaminated cat feces or undercooked meat.
4. Leptospirosis: a bacterial infection caused by Leptospira interrogans, which is spread to humans through contact with contaminated water or soil.
5. Avian influenza (bird flu): a viral infection that can be transmitted to humans through contact with infected birds or contaminated surfaces.

Transmission of Zoonoses

Zoonoses can be transmitted to humans in a variety of ways, including:

1. Direct contact with infected animals or contaminated animal products.
2. Contact with contaminated soil, water, or other environmental sources.
3. Through vectors such as ticks, mosquitoes, and fleas.
4. By consuming contaminated food or water.
5. Through close contact with an infected person or animal.

Prevention of Zoonoses

Preventing the transmission of zoonoses requires a combination of personal protective measures, good hygiene practices, and careful handling of animals and animal products. Some strategies for preventing zoonoses include:

1. Washing hands frequently, especially after contact with animals or their waste.
2. Avoiding direct contact with wild animals and avoiding touching or feeding stray animals.
3. Cooking meat and eggs thoroughly to kill harmful bacteria.
4. Keeping pets up to date on vaccinations and preventative care.
5. Avoiding consumption of raw or undercooked meat, particularly poultry and pork.
6. Using insect repellents and wearing protective clothing when outdoors in areas where vectors are prevalent.
7. Implementing proper sanitation and hygiene practices in animal housing and husbandry.
8. Implementing strict biosecurity measures on farms and in animal facilities to prevent the spread of disease.
9. Providing education and training to individuals working with animals or in areas where zoonoses are prevalent.
10. Monitoring for and reporting cases of zoonotic disease to help track and control outbreaks.

Conclusion

Zoonoses are diseases that can be transmitted between animals and humans, posing a significant risk to human health and animal welfare. Understanding the causes, transmission, and prevention of zoonoses is essential for protecting both humans and animals from these diseases. By implementing appropriate measures such as avoiding contact with wild animals, cooking meat thoroughly, keeping pets up to date on vaccinations, and implementing proper sanitation and biosecurity practices, we can reduce the risk of zoonotic disease transmission and protect public health and animal welfare.

The different types of Neurotoxicity Syndromes include:

1. Organophosphate-induced neurotoxicity: This syndrome is caused by exposure to organophosphate pesticides, which can damage the nervous system and cause symptoms such as headaches, dizziness, and memory loss.
2. Heavy metal neurotoxicity: Exposure to heavy metals, such as lead, mercury, and arsenic, can damage the nervous system and cause symptoms such as tremors, muscle weakness, and cognitive impairment.
3. Pesticide-induced neurotoxicity: This syndrome is caused by exposure to pesticides, which can damage the nervous system and cause symptoms such as headaches, dizziness, and memory loss.
4. Solvent-induced neurotoxicity: Exposure to solvents, such as toluene and benzene, can damage the nervous system and cause symptoms such as memory loss, difficulty with concentration, and mood changes.
5. Medication-induced neurotoxicity: Certain medications, such as antidepressants and antipsychotics, can damage the nervous system and cause symptoms such as tremors, muscle rigidity, and cognitive impairment.
6. Environmental neurotoxicity: Exposure to environmental toxins, such as air pollution and pesticides, can damage the nervous system and cause symptoms such as headaches, dizziness, and memory loss.
7. Neurodegenerative disease-induced neurotoxicity: Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, can cause neurotoxicity and lead to symptoms such as cognitive decline, memory loss, and motor dysfunction.
8. Traumatic brain injury-induced neurotoxicity: Traumatic brain injury can cause neurotoxicity and lead to symptoms such as cognitive impairment, memory loss, and mood changes.
9. Stroke-induced neurotoxicity: A stroke can cause neurotoxicity and lead to symptoms such as weakness or paralysis on one side of the body, difficulty with speech and language, and memory loss.
10. Neurodevelopmental disorder-induced neurotoxicity: Neurodevelopmental disorders, such as autism spectrum disorder, can cause neurotoxicity and lead to symptoms such as cognitive impairment, social withdrawal, and repetitive behaviors.

It is important to note that these are just a few examples of the many different types of neurotoxicity that can occur, and that each type may have its own unique set of causes, symptoms, and treatments. If you suspect that you or someone you know may be experiencing neurotoxicity, it is important to seek medical attention as soon as possible in order to receive an accurate diagnosis and appropriate treatment.

Body weight is an important health indicator, as it can affect an individual's risk for certain medical conditions, such as obesity, diabetes, and cardiovascular disease. Maintaining a healthy body weight is essential for overall health and well-being, and there are many ways to do so, including a balanced diet, regular exercise, and other lifestyle changes.

There are several ways to measure body weight, including:

1. Scale: This is the most common method of measuring body weight, and it involves standing on a scale that displays the individual's weight in kg or lb.
2. Body fat calipers: These are used to measure body fat percentage by pinching the skin at specific points on the body.
3. Skinfold measurements: This method involves measuring the thickness of the skin folds at specific points on the body to estimate body fat percentage.
4. Bioelectrical impedance analysis (BIA): This is a non-invasive method that uses electrical impulses to measure body fat percentage.
5. Dual-energy X-ray absorptiometry (DXA): This is a more accurate method of measuring body composition, including bone density and body fat percentage.

It's important to note that body weight can fluctuate throughout the day due to factors such as water retention, so it's best to measure body weight at the same time each day for the most accurate results. Additionally, it's important to use a reliable scale or measuring tool to ensure accurate measurements.

Thromboembolism can be caused by a variety of factors, such as injury, surgery, cancer, and certain medical conditions like atrial fibrillation. It can also be inherited or acquired through genetic mutations.

The symptoms of thromboembolism depend on the location of the clot and the severity of the blockage. They may include:

* Swelling or redness in the affected limb
* Pain or tenderness in the affected area
* Weakness or numbness in the affected limb
* Shortness of breath or chest pain if the clot has traveled to the lungs (pulmonary embolism)
* Dizziness, lightheadedness, or fainting

Thromboembolism can be diagnosed through a variety of tests, such as ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and blood tests. Treatment typically involves anticoagulant medications to prevent the clot from growing and to prevent new clots from forming. In some cases, thrombolysis or clot-busting drugs may be used to dissolve the clot. Filters can also be placed in the vena cava to prevent clots from traveling to the lungs.

Prevention of thromboembolism includes:

* Moving around regularly to improve blood flow
* Avoiding long periods of immobility, such as during long-distance travel
* Elevating the affected limb to reduce swelling
* Compression stockings to improve blood flow
* Avoiding smoking and managing weight
* Taking anticoagulant medications if recommended by a healthcare provider.

Type 2 diabetes can be managed through a combination of diet, exercise, and medication. In some cases, lifestyle changes may be enough to control blood sugar levels, while in other cases, medication or insulin therapy may be necessary. Regular monitoring of blood sugar levels and follow-up with a healthcare provider are important for managing the condition and preventing complications.

Common symptoms of type 2 diabetes include:

* Increased thirst and urination
* Fatigue
* Blurred vision
* Cuts or bruises that are slow to heal
* Tingling or numbness in the hands and feet
* Recurring skin, gum, or bladder infections

If left untreated, type 2 diabetes can lead to a range of complications, including:

* Heart disease and stroke
* Kidney damage and failure
* Nerve damage and pain
* Eye damage and blindness
* Foot damage and amputation

The exact cause of type 2 diabetes is not known, but it is believed to be linked to a combination of genetic and lifestyle factors, such as:

* Obesity and excess body weight
* Lack of physical activity
* Poor diet and nutrition
* Age and family history
* Certain ethnicities (e.g., African American, Hispanic/Latino, Native American)
* History of gestational diabetes or delivering a baby over 9 lbs.

There is no cure for type 2 diabetes, but it can be managed and controlled through a combination of lifestyle changes and medication. With proper treatment and self-care, people with type 2 diabetes can lead long, healthy lives.

There are several different types of obesity, including:

1. Central obesity: This type of obesity is characterized by excess fat around the waistline, which can increase the risk of health problems such as type 2 diabetes and cardiovascular disease.
2. Peripheral obesity: This type of obesity is characterized by excess fat in the hips, thighs, and arms.
3. Visceral obesity: This type of obesity is characterized by excess fat around the internal organs in the abdominal cavity.
4. Mixed obesity: This type of obesity is characterized by both central and peripheral obesity.

Obesity can be caused by a variety of factors, including genetics, lack of physical activity, poor diet, sleep deprivation, and certain medications. Treatment for obesity typically involves a combination of lifestyle changes, such as increased physical activity and a healthy diet, and in some cases, medication or surgery may be necessary to achieve weight loss.

Preventing obesity is important for overall health and well-being, and can be achieved through a variety of strategies, including:

1. Eating a healthy, balanced diet that is low in added sugars, saturated fats, and refined carbohydrates.
2. Engaging in regular physical activity, such as walking, jogging, or swimming.
3. Getting enough sleep each night.
4. Managing stress levels through relaxation techniques, such as meditation or deep breathing.
5. Avoiding excessive alcohol consumption and quitting smoking.
6. Monitoring weight and body mass index (BMI) on a regular basis to identify any changes or potential health risks.
7. Seeking professional help from a healthcare provider or registered dietitian for personalized guidance on weight management and healthy lifestyle choices.

1. Preeclampsia: A condition characterized by high blood pressure during pregnancy, which can lead to complications such as stroke or premature birth.
2. Gestational diabetes: A type of diabetes that develops during pregnancy, which can cause complications for both the mother and the baby if left untreated.
3. Placenta previa: A condition in which the placenta is located low in the uterus, covering the cervix, which can cause bleeding and other complications.
4. Premature labor: Labor that occurs before 37 weeks of gestation, which can increase the risk of health problems for the baby.
5. Fetal distress: A condition in which the fetus is not getting enough oxygen, which can lead to serious health problems or even death.
6. Postpartum hemorrhage: Excessive bleeding after delivery, which can be life-threatening if left untreated.
7. Cesarean section (C-section) complications: Complications that may arise during a C-section, such as infection or bleeding.
8. Maternal infections: Infections that the mother may contract during pregnancy or childbirth, such as group B strep or urinary tract infections.
9. Preterm birth: Birth that occurs before 37 weeks of gestation, which can increase the risk of health problems for the baby.
10. Chromosomal abnormalities: Genetic disorders that may affect the baby's growth and development, such as Down syndrome or Turner syndrome.

It is important for pregnant women to receive regular prenatal care to monitor for any potential complications and ensure a healthy pregnancy outcome. In some cases, pregnancy complications may require medical interventions, such as hospitalization or surgery, to ensure the safety of both the mother and the baby.

Examples of acute diseases include:

1. Common cold and flu
2. Pneumonia and bronchitis
3. Appendicitis and other abdominal emergencies
4. Heart attacks and strokes
5. Asthma attacks and allergic reactions
6. Skin infections and cellulitis
7. Urinary tract infections
8. Sinusitis and meningitis
9. Gastroenteritis and food poisoning
10. Sprains, strains, and fractures.

Acute diseases can be treated effectively with antibiotics, medications, or other therapies. However, if left untreated, they can lead to chronic conditions or complications that may require long-term care. Therefore, it is important to seek medical attention promptly if symptoms persist or worsen over time.

There are two types of hypertension:

1. Primary Hypertension: This type of hypertension has no identifiable cause and is also known as essential hypertension. It accounts for about 90% of all cases of hypertension.
2. Secondary Hypertension: This type of hypertension is caused by an underlying medical condition or medication. It accounts for about 10% of all cases of hypertension.

Some common causes of secondary hypertension include:

* Kidney disease
* Adrenal gland disorders
* Hormonal imbalances
* Certain medications
* Sleep apnea
* Cocaine use

There are also several risk factors for hypertension, including:

* Age (the risk increases with age)
* Family history of hypertension
* Obesity
* Lack of exercise
* High sodium intake
* Low potassium intake
* Stress

Hypertension is often asymptomatic, and it can cause damage to the blood vessels and organs over time. Some potential complications of hypertension include:

* Heart disease (e.g., heart attacks, heart failure)
* Stroke
* Kidney disease (e.g., chronic kidney disease, end-stage renal disease)
* Vision loss (e.g., retinopathy)
* Peripheral artery disease

Hypertension is typically diagnosed through blood pressure readings taken over a period of time. Treatment for hypertension may include lifestyle changes (e.g., diet, exercise, stress management), medications, or a combination of both. The goal of treatment is to reduce the risk of complications and improve quality of life.

There are several different types of pain, including:

1. Acute pain: This type of pain is sudden and severe, and it usually lasts for a short period of time. It can be caused by injuries, surgery, or other forms of tissue damage.
2. Chronic pain: This type of pain persists over a long period of time, often lasting more than 3 months. It can be caused by conditions such as arthritis, fibromyalgia, or nerve damage.
3. Neuropathic pain: This type of pain results from damage to the nervous system, and it can be characterized by burning, shooting, or stabbing sensations.
4. Visceral pain: This type of pain originates in the internal organs, and it can be difficult to localize.
5. Psychogenic pain: This type of pain is caused by psychological factors such as stress, anxiety, or depression.

The medical field uses a range of methods to assess and manage pain, including:

1. Pain rating scales: These are numerical scales that patients use to rate the intensity of their pain.
2. Pain diaries: These are records that patients keep to track their pain over time.
3. Clinical interviews: Healthcare providers use these to gather information about the patient's pain experience and other relevant symptoms.
4. Physical examination: This can help healthcare providers identify any underlying causes of pain, such as injuries or inflammation.
5. Imaging studies: These can be used to visualize the body and identify any structural abnormalities that may be contributing to the patient's pain.
6. Medications: There are a wide range of medications available to treat pain, including analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), and muscle relaxants.
7. Alternative therapies: These can include acupuncture, massage, and physical therapy.
8. Interventional procedures: These are minimally invasive procedures that can be used to treat pain, such as nerve blocks and spinal cord stimulation.

It is important for healthcare providers to approach pain management with a multi-modal approach, using a combination of these methods to address the physical, emotional, and social aspects of pain. By doing so, they can help improve the patient's quality of life and reduce their suffering.

There are several types of diabetes mellitus, including:

1. Type 1 DM: This is an autoimmune condition in which the body's immune system attacks and destroys the cells in the pancreas that produce insulin, resulting in a complete deficiency of insulin production. It typically develops in childhood or adolescence, and patients with this condition require lifelong insulin therapy.
2. Type 2 DM: This is the most common form of diabetes, accounting for around 90% of all cases. It is caused by a combination of insulin resistance (where the body's cells do not respond properly to insulin) and impaired insulin secretion. It is often associated with obesity, physical inactivity, and a diet high in sugar and unhealthy fats.
3. Gestational DM: This type of diabetes develops during pregnancy, usually in the second or third trimester. Hormonal changes and insulin resistance can cause blood sugar levels to rise, putting both the mother and baby at risk.
4. LADA (Latent Autoimmune Diabetes in Adults): This is a form of type 1 DM that develops in adults, typically after the age of 30. It shares features with both type 1 and type 2 DM.
5. MODY (Maturity-Onset Diabetes of the Young): This is a rare form of diabetes caused by genetic mutations that affect insulin production. It typically develops in young adulthood and can be managed with lifestyle changes and/or medication.

The symptoms of diabetes mellitus can vary depending on the severity of the condition, but may include:

1. Increased thirst and urination
2. Fatigue
3. Blurred vision
4. Cuts or bruises that are slow to heal
5. Tingling or numbness in hands and feet
6. Recurring skin, gum, or bladder infections
7. Flu-like symptoms such as weakness, dizziness, and stomach pain
8. Dark, velvety skin patches (acanthosis nigricans)
9. Yellowish color of the skin and eyes (jaundice)
10. Delayed healing of cuts and wounds

If left untreated, diabetes mellitus can lead to a range of complications, including:

1. Heart disease and stroke
2. Kidney damage and failure
3. Nerve damage (neuropathy)
4. Eye damage (retinopathy)
5. Foot damage (neuropathic ulcers)
6. Cognitive impairment and dementia
7. Increased risk of infections and other diseases, such as pneumonia, gum disease, and urinary tract infections.

It is important to note that not all individuals with diabetes will experience these complications, and that proper management of the condition can greatly reduce the risk of developing these complications.

Malignant prostatic neoplasms are cancerous tumors that can be aggressive and spread to other parts of the body (metastasize). The most common type of malignant prostatic neoplasm is adenocarcinoma of the prostate, which accounts for approximately 95% of all prostate cancers. Other types of malignant prostatic neoplasms include sarcomas and small cell carcinomas.

Prostatic neoplasms can be diagnosed through a variety of tests such as digital rectal examination (DRE), prostate-specific antigen (PSA) test, imaging studies (ultrasound, CT scan or MRI), and biopsy. Treatment options for prostatic neoplasms depend on the type, stage, and grade of the tumor, as well as the patient's age and overall health. Treatment options can include active surveillance, surgery (robotic-assisted laparoscopic prostatectomy or open prostatectomy), radiation therapy (external beam radiation therapy or brachytherapy), and hormone therapy.

In summary, Prostatic Neoplasms are tumors that occur in the prostate gland, which can be benign or malignant. The most common types of malignant prostatic neoplasms are adenocarcinoma of the prostate, and other types include sarcomas and small cell carcinomas. Diagnosis is done through a variety of tests, and treatment options depend on the type, stage, and grade of the tumor, as well as the patient's age and overall health.

There are several types of disease susceptibility, including:

1. Genetic predisposition: This refers to the inherent tendency of an individual to develop a particular disease due to their genetic makeup. For example, some families may have a higher risk of developing certain diseases such as cancer or heart disease due to inherited genetic mutations.
2. Environmental susceptibility: This refers to the increased risk of developing a disease due to exposure to environmental factors such as pollutants, toxins, or infectious agents. For example, someone who lives in an area with high levels of air pollution may be more susceptible to developing respiratory problems.
3. Lifestyle susceptibility: This refers to the increased risk of developing a disease due to unhealthy lifestyle choices such as smoking, lack of exercise, or poor diet. For example, someone who smokes and is overweight may be more susceptible to developing heart disease or lung cancer.
4. Immune system susceptibility: This refers to the increased risk of developing a disease due to an impaired immune system. For example, people with autoimmune disorders such as HIV/AIDS or rheumatoid arthritis may be more susceptible to opportunistic infections.

Understanding disease susceptibility can help healthcare providers identify individuals who are at risk of developing certain diseases and provide preventive measures or early intervention to reduce the risk of disease progression. Additionally, genetic testing can help identify individuals with a high risk of developing certain diseases, allowing for earlier diagnosis and treatment.

In summary, disease susceptibility refers to the predisposition of an individual to develop a particular disease or condition due to various factors such as genetics, environment, lifestyle choices, and immune system function. Understanding disease susceptibility can help healthcare providers identify individuals at risk and provide appropriate preventive measures or early intervention to reduce the risk of disease progression.

Some common examples of drug-induced abnormalities include:

1. Allergic reactions: Some drugs can cause an allergic reaction, which can lead to symptoms such as hives, itching, swelling, and difficulty breathing.
2. Side effects: Many drugs can cause side effects, such as nausea, dizziness, and fatigue, which can be mild or severe.
3. Toxic reactions: Some drugs can cause toxic reactions, which can damage the body's organs and tissues.
4. Autoimmune disorders: Certain drugs can trigger autoimmune disorders, such as lupus or rheumatoid arthritis, which can cause a range of symptoms including joint pain, fatigue, and skin rashes.
5. Gastrointestinal problems: Some drugs can cause gastrointestinal problems, such as stomach ulcers, diarrhea, or constipation.
6. Neurological disorders: Certain drugs can cause neurological disorders, such as seizures, tremors, and changes in mood or behavior.
7. Cardiovascular problems: Some drugs can increase the risk of cardiovascular problems, such as heart attack or stroke.
8. Metabolic changes: Certain drugs can cause metabolic changes, such as weight gain or loss, and changes in blood sugar levels.
9. Endocrine disorders: Some drugs can affect the body's endocrine system, leading to hormonal imbalances and a range of symptoms including changes in mood, energy levels, and sexual function.
10. Kidney damage: Certain drugs can cause kidney damage or failure, especially in people with pre-existing kidney problems.

It's important to note that not all drugs will cause side effects, and the severity of side effects can vary depending on the individual and the specific drug being taken. However, it's important to be aware of the potential risks associated with any medication you are taking, and to discuss any concerns or questions you have with your healthcare provider.

The term "asymptomatic" means "not showing symptoms."

In medical terminology, the word asymptomatic is used to describe a person who has a disease or condition but does not show any symptoms. Symptoms are changes in the body or mind that indicate the presence of a disease or condition. For example, fever, pain, and fatigue are all symptoms of an infection.

Asymptomatic diseases can be difficult to diagnose because they do not cause any noticeable symptoms. In many cases, these diseases are only discovered through routine medical testing or exams. For example, a person may have high blood pressure without knowing it, as there are usually no noticeable symptoms until the condition is advanced.

The importance of screening tests and early diagnosis

Screening tests are medical tests that are performed on people who do not have any symptoms of a disease or condition. These tests are designed to detect diseases or conditions before they cause any noticeable symptoms. Examples of screening tests include blood pressure checks, cholesterol tests, mammograms, and colonoscopies.

Early diagnosis is critical for successfully treating many asymptomatic diseases. When a disease or condition is detected early, it can be treated more effectively before it causes any significant damage. In some cases, early diagnosis may even prevent the development of complications.

The importance of screening tests and early diagnosis cannot be overstated. By detecting diseases or conditions before they cause symptoms, individuals can receive treatment before any long-term damage occurs. This can help to improve their quality of life, increase their lifespan, and reduce the risk of complications.

The importance of screening tests and early diagnosis is particularly important for certain populations, such as older adults or those with a family history of certain diseases or conditions. These individuals may be at a higher risk for developing certain asymptomatic diseases, and screening tests can help to detect these conditions before they cause any noticeable symptoms.

The benefits of early diagnosis include:

1. Improved treatment outcomes: When a disease or condition is detected early, it can be treated more effectively before it causes any significant damage. This can improve the chances of successful treatment and reduce the risk of complications.
2. Prevention of long-term damage: By detecting diseases or conditions before they cause any noticeable symptoms, individuals can receive treatment before any long-term damage occurs. This can help to preserve their quality of life and increase their lifespan.
3. Reduced healthcare costs: Early diagnosis can reduce healthcare costs by preventing the need for more expensive treatments or hospitalizations that may be required if a condition is allowed to progress untreated.
4. Increased awareness: Screening tests and early diagnosis can increase awareness of certain diseases or conditions, which can lead to increased education and advocacy efforts aimed at prevention and treatment.
5. Improved patient outcomes: Early diagnosis can lead to improved patient outcomes by allowing for earlier intervention and treatment, which can improve the chances of successful treatment and reduce the risk of complications.
6. Reduced suffering: By detecting diseases or conditions before they cause any noticeable symptoms, individuals can receive treatment before they experience any unnecessary suffering.
7. Increased survival rates: Early diagnosis can lead to increased survival rates for certain diseases or conditions, particularly those that are more treatable when detected early.
8. Better management of chronic conditions: Screening tests and early diagnosis can help individuals with chronic conditions to manage their condition more effectively, which can improve their quality of life and increase their lifespan.
9. Improved patient satisfaction: Early diagnosis can lead to improved patient satisfaction by providing individuals with a sense of control over their health and well-being.
10. Reduced anxiety: By detecting diseases or conditions before they cause any noticeable symptoms, individuals may experience reduced anxiety about their health and well-being.

Overall, early diagnosis has the potential to significantly improve patient outcomes and quality of life for individuals with a wide range of medical conditions. It is important for healthcare providers to prioritize early diagnosis and screening tests in order to provide the best possible care for their patients.

Down syndrome can be diagnosed before birth through prenatal testing, such as chorionic villus sampling or amniocentesis, or after birth through a blood test. The symptoms of Down syndrome can vary from person to person, but common physical features include:

* A flat face with a short neck and small ears
* A short stature
* A wide, short hands with short fingers
* A small head
* Almond-shaped eyes that are slanted upward
* A single crease in the palm of the hand

People with Down syndrome may also have cognitive delays and intellectual disability, as well as increased risk of certain medical conditions such as heart defects, gastrointestinal problems, and hearing and vision loss.

There is no cure for Down syndrome, but early intervention and proper medical care can greatly improve the quality of life for individuals with the condition. Treatment may include speech and language therapy, occupational therapy, physical therapy, and special education programs. With appropriate support and resources, people with Down syndrome can lead fulfilling and productive lives.

There are several different types of calcinosis, each with its own unique causes and symptoms. Some common forms of calcinosis include:

1. Dystrophic calcinosis: This type of calcinosis occurs in people with muscular dystrophy, a group of genetic disorders that affect muscle strength and function. Dystrophic calcinosis can cause calcium deposits to form in the muscles, leading to muscle weakness and wasting.
2. Metastatic calcinosis: This type of calcinosis occurs when cancer cells spread to other parts of the body and cause calcium deposits to form. Metastatic calcinosis can occur in people with a variety of different types of cancer, including breast, lung, and prostate cancer.
3. Idiopathic calcinosis: This type of calcinosis occurs for no apparent reason, and the exact cause is not known. Idiopathic calcinosis can affect people of all ages and can cause calcium deposits to form in a variety of different tissues.
4. Secondary calcinosis: This type of calcidosis occurs as a result of an underlying medical condition or injury. For example, secondary calcinosis can occur in people with kidney disease, hyperparathyroidism (a condition in which the parathyroid glands produce too much parathyroid hormone), or traumatic injuries.

Treatment for calcinosis depends on the underlying cause and the severity of the condition. In some cases, treatment may involve managing the underlying disease or condition that is causing the calcium deposits to form. Other treatments may include medications to reduce inflammation and pain, physical therapy to improve mobility and strength, and surgery to remove the calcium deposits.

There are several types of hip fractures, including:

1. Femoral neck fracture: A break in the thin neck of the femur just above the base of the thigh bone.
2. Subtrochanteric fracture: A break between the lesser trochanter (a bony prominence on the upper end of the femur) and the neck of the femur.
3. Diaphyseal fracture: A break in the shaft of the femur, which is the longest part of the bone.
4. Metaphyseal fracture: A break in the area where the thigh bone meets the pelvis.

Hip fractures can be caused by a variety of factors, including:

1. Osteoporosis: A condition that causes brittle and weak bones, making them more susceptible to fractures.
2. Trauma: A fall or injury that causes a direct blow to the hip.
3. Overuse: Repetitive strain on the bone, such as from sports or repetitive movements.
4. Medical conditions: Certain medical conditions, such as osteopenia (low bone density) or Paget's disease (a condition that causes abnormal bone growth), can increase the risk of hip fractures.

Treatment for hip fractures typically involves surgery to realign and stabilize the bones. This may involve inserting plates, screws, or rods to hold the bones in place while they heal. In some cases, a total hip replacement may be necessary. After surgery, physical therapy is often recommended to help regain strength and mobility in the affected limb.

Preventive measures for hip fractures include:

1. Exercise: Regular exercise, such as weight-bearing activities like walking or running, can help maintain bone density and reduce the risk of hip fractures.
2. Diet: A diet rich in calcium and vitamin D can help support bone health.
3. Fall prevention: Taking steps to prevent falls, such as removing tripping hazards from the home and using handrails, can help reduce the risk of hip fractures.
4. Osteoporosis treatment: If you have osteoporosis, medications or other treatments may be recommended to help strengthen your bones and reduce the risk of hip fractures.

People with pica may eat these items in secret and experience a sense of relief or satisfaction after consuming them. The condition is more common in children and adolescents, but it can also affect adults. Pica can lead to nutritional deficiencies, gastrointestinal problems, and other health issues if the eaten items are not digestible or contain harmful substances.

Treatment for pica usually involves addressing any underlying mental health issues and providing education on nutrition and healthy eating habits. In some cases, medication may be prescribed to help manage symptoms. It is important to seek medical attention if you or someone you know is experiencing symptoms of pica, as early intervention can help prevent complications and improve overall health.

HIV (human immunodeficiency virus) infection is a condition in which the body is infected with HIV, a type of retrovirus that attacks the body's immune system. HIV infection can lead to AIDS (acquired immunodeficiency syndrome), a condition in which the immune system is severely damaged and the body is unable to fight off infections and diseases.

There are several ways that HIV can be transmitted, including:

1. Sexual contact with an infected person
2. Sharing of needles or other drug paraphernalia with an infected person
3. Mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Blood transfusions ( although this is rare in developed countries due to screening processes)
5. Organ transplantation (again, rare)

The symptoms of HIV infection can be mild at first and may not appear until several years after infection. These symptoms can include:

1. Fever
2. Fatigue
3. Swollen glands in the neck, armpits, and groin
4. Rash
5. Muscle aches and joint pain
6. Night sweats
7. Diarrhea
8. Weight loss

If left untreated, HIV infection can progress to AIDS, which is a life-threatening condition that can cause a wide range of symptoms, including:

1. Opportunistic infections (such as pneumocystis pneumonia)
2. Cancer (such as Kaposi's sarcoma)
3. Wasting syndrome
4. Neurological problems (such as dementia and seizures)

HIV infection is diagnosed through a combination of blood tests and physical examination. Treatment typically involves antiretroviral therapy (ART), which is a combination of medications that work together to suppress the virus and slow the progression of the disease.

Prevention methods for HIV infection include:

1. Safe sex practices, such as using condoms and dental dams
2. Avoiding sharing needles or other drug-injecting equipment
3. Avoiding mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Post-exposure prophylaxis (PEP), which is a short-term treatment that can prevent infection after potential exposure to the virus
5. Pre-exposure prophylaxis (PrEP), which is a daily medication that can prevent infection in people who are at high risk of being exposed to the virus.

It's important to note that HIV infection is manageable with proper treatment and care, and that people living with HIV can lead long and healthy lives. However, it's important to be aware of the risks and take steps to prevent transmission.

Types of experimental neoplasms include:

* Xenografts: tumors that are transplanted into animals from another species, often humans.
* Transgenic tumors: tumors that are created by introducing cancer-causing genes into an animal's genome.
* Chemically-induced tumors: tumors that are caused by exposure to certain chemicals or drugs.

The use of experimental neoplasms in research has led to significant advances in our understanding of cancer biology and the development of new treatments for the disease. However, the use of animals in cancer research is a controversial topic and alternatives to animal models are being developed and implemented.

Types of Substance-Related Disorders:

1. Alcohol Use Disorder (AUD): A chronic disease characterized by the excessive consumption of alcohol, leading to impaired control over drinking, social or personal problems, and increased risk of health issues.
2. Opioid Use Disorder (OUD): A chronic disease characterized by the excessive use of opioids, such as prescription painkillers or heroin, leading to withdrawal symptoms when the substance is not available.
3. Stimulant Use Disorder: A chronic disease characterized by the excessive use of stimulants, such as cocaine or amphetamines, leading to impaired control over use and increased risk of adverse effects.
4. Cannabis Use Disorder: A chronic disease characterized by the excessive use of cannabis, leading to impaired control over use and increased risk of adverse effects.
5. Hallucinogen Use Disorder: A chronic disease characterized by the excessive use of hallucinogens, such as LSD or psilocybin mushrooms, leading to impaired control over use and increased risk of adverse effects.

Causes and Risk Factors:

1. Genetics: Individuals with a family history of substance-related disorders are more likely to develop these conditions.
2. Mental health: Individuals with mental health conditions, such as depression or anxiety, may be more likely to use substances as a form of self-medication.
3. Environmental factors: Exposure to substances at an early age, peer pressure, and social environment can increase the risk of developing a substance-related disorder.
4. Brain chemistry: Substance use can alter brain chemistry, leading to dependence and addiction.

Symptoms:

1. Increased tolerance: The need to use more of the substance to achieve the desired effect.
2. Withdrawal: Experiencing symptoms such as anxiety, irritability, or nausea when the substance is not present.
3. Loss of control: Using more substance than intended or for longer than intended.
4. Neglecting responsibilities: Neglecting responsibilities at home, work, or school due to substance use.
5. Continued use despite negative consequences: Continuing to use the substance despite physical, emotional, or financial consequences.

Diagnosis:

1. Physical examination: A doctor may perform a physical examination to look for signs of substance use, such as track marks or changes in heart rate and blood pressure.
2. Laboratory tests: Blood or urine tests can confirm the presence of substances in the body.
3. Psychological evaluation: A mental health professional may conduct a psychological evaluation to assess symptoms of substance-related disorders and determine the presence of co-occurring conditions.

Treatment:

1. Detoxification: A medically-supervised detox program can help manage withdrawal symptoms and reduce the risk of complications.
2. Medications: Medications such as methadone or buprenorphine may be prescribed to manage withdrawal symptoms and reduce cravings.
3. Behavioral therapy: Cognitive-behavioral therapy (CBT) and contingency management are effective behavioral therapies for treating substance use disorders.
4. Support groups: Joining a support group such as Narcotics Anonymous can provide a sense of community and support for individuals in recovery.
5. Lifestyle changes: Making healthy lifestyle changes such as regular exercise, healthy eating, and getting enough sleep can help manage withdrawal symptoms and reduce cravings.

It's important to note that diagnosis and treatment of substance-related disorders is a complex process and should be individualized based on the specific needs and circumstances of each patient.

There are three main types of silicosis:

1. Acute silicosis: This type of silicosis occurs shortly after exposure to high levels of silica dust and is often seen in workers who have been exposed to very high concentrations of silica for a short period of time, such as in a mines or quarries. Symptoms include coughing, fever, and difficulty breathing.
2. Chronic silicosis: This type of silicosis occurs after long-term exposure to lower levels of silica dust and is the most common form of the disease. Symptoms may not appear until years after exposure and can include shortness of breath, coughing, and fatigue.
3. Accelerated silicosis: This type of silicosis is a combination of acute and chronic silicosis and is typically seen in workers who have been exposed to high levels of silica dust for an extended period of time. Symptoms can include all of those listed for acute and chronic silicosis, as well as weight loss and night sweats.

Silicosis is diagnosed through a combination of physical examination, medical history, and lung function tests. Chest X-rays and CT scans may also be used to confirm the presence of silicosis and assess its severity. There is no cure for silicosis, but treatment can help manage symptoms and slow the progression of the disease. This may include medications to reduce inflammation and improve lung function, as well as respiratory therapy and oxygen therapy. In severe cases, lung transplantation may be necessary.

Prevention is key in reducing the risk of developing silicosis. This includes using proper ventilation and protection equipment when working with silica-containing materials, implementing strict safety protocols, and providing adequate training and education to workers. Regular monitoring of worker exposure levels can also help identify and address any potential risks before they become serious.

In conclusion, silicosis is a debilitating and potentially fatal respiratory disease caused by the inhalation of silica dust. While there is no cure for silicosis, early diagnosis and appropriate treatment can help manage symptoms and slow the progression of the disease. Prevention through proper safety protocols and monitoring of worker exposure levels is crucial in reducing the risk of developing silicosis.

Symptoms of venous thrombosis may include pain, swelling, warmth, and redness in the affected limb. In some cases, the clot can break loose and travel to the lungs, causing a potentially life-threatening condition called Pulmonary Embolism (PE).

Treatment for venous thrombosis typically involves anticoagulant medications to prevent the clot from growing and to prevent new clots from forming. In some cases, a filter may be placed in the vena cava, the large vein that carries blood from the lower body to the heart, to prevent clots from traveling to the lungs.

Prevention of venous thrombosis includes encouraging movement and exercise, avoiding long periods of immobility, and wearing compression stockings or sleeves to compress the veins and improve blood flow.

There are two main types of noise-induced hearing loss:

1. Acoustic trauma: This type of hearing loss occurs suddenly after a single exposure to an extremely loud noise, such as an explosion or a gunshot.
2. Cumulative trauma: This type of hearing loss occurs gradually over time as a result of repeated exposure to loud noises, such as machinery or music.

The risk of developing noise-induced hearing loss increases with the intensity and duration of noise exposure. Factors that can contribute to an individual's risk of developing NIHL include:

1. Loudness of the noise: Noises that are louder than 85 decibels can cause permanent damage to the hair cells in the inner ear.
2. Prolonged exposure: The longer an individual is exposed to loud noises, the greater their risk of developing NIHL.
3. Age: Older adults are more susceptible to noise-induced hearing loss due to the natural aging process and the degeneration of the hair cells in the inner ear.
4. Genetics: Some individuals may be more susceptible to noise-induced hearing loss due to genetic factors.
5. Other medical conditions: Certain medical conditions, such as diabetes or otosclerosis, can increase an individual's risk of developing NIHL.

The symptoms of noise-induced hearing loss can vary depending on the severity of the damage. Some common symptoms include:

1. Difficulty hearing high-pitched sounds
2. Difficulty understanding speech in noisy environments
3. Ringing or buzzing in the ears (tinnitus)
4. Muffled hearing
5. Decreased sensitivity to sounds

There is currently no cure for noise-induced hearing loss, but there are several treatment options available to help manage the symptoms. These include:

1. Hearing aids: These can help amplify sounds and improve an individual's ability to hear.
2. Cochlear implants: These are electronic devices that are surgically implanted in the inner ear and can bypass damaged hair cells to directly stimulate the auditory nerve.
3. Tinnitus management: There are several techniques and therapies available to help manage tinnitus, including sound therapy, counseling, and relaxation techniques.
4. Speech therapy: This can help individuals with hearing loss improve their communication skills and better understand speech in noisy environments.

Prevention is key when it comes to noise-induced hearing loss. To reduce your risk of developing NIHL, you should:

1. Avoid loud noises whenever possible
2. Wear earplugs or earmuffs when exposed to loud noises
3. Take regular breaks in a quiet space if you are working in a loud environment
4. Keep the volume down on personal audio devices
5. Get your hearing checked regularly to identify any potential issues early on.

Acute wounds and injuries are those that occur suddenly and heal within a relatively short period of time, usually within a few days or weeks. Examples of acute wounds include cuts, scrapes, and burns. Chronic wounds and injuries, on the other hand, are those that persist over a longer period of time and may not heal properly, leading to long-term complications. Examples of chronic wounds include diabetic foot ulcers, pressure ulcers, and chronic back pain.

Wounds and injuries can be caused by a variety of factors, including accidents, sports injuries, violence, and medical conditions such as diabetes or circulatory problems. Treatment for wounds and injuries depends on the severity of the injury and may include cleaning and dressing the wound, applying antibiotics, immobilizing broken bones, and providing pain management. In some cases, surgery may be necessary to repair damaged tissues or restore function.

Preventive measures for wounds and injuries include wearing appropriate protective gear during activities such as sports or work, following safety protocols to avoid accidents, maintaining proper hygiene and nutrition to prevent infection, and seeking medical attention promptly if an injury occurs.

Overall, wounds and injuries can have a significant impact on an individual's quality of life, and it is important to seek medical attention promptly if symptoms persist or worsen over time. Proper treatment and management of wounds and injuries can help to promote healing, reduce the risk of complications, and improve long-term outcomes.

Myocardial ischemia can be caused by a variety of factors, including coronary artery disease, high blood pressure, diabetes, and smoking. It can also be triggered by physical exertion or stress.

There are several types of myocardial ischemia, including:

1. Stable angina: This is the most common type of myocardial ischemia, and it is characterized by a predictable pattern of chest pain that occurs during physical activity or emotional stress.
2. Unstable angina: This is a more severe type of myocardial ischemia that can occur without any identifiable trigger, and can be accompanied by other symptoms such as shortness of breath or vomiting.
3. Acute coronary syndrome (ACS): This is a condition that includes both stable angina and unstable angina, and it is characterized by a sudden reduction in blood flow to the heart muscle.
4. Heart attack (myocardial infarction): This is a type of myocardial ischemia that occurs when the blood flow to the heart muscle is completely blocked, resulting in damage or death of the cardiac tissue.

Myocardial ischemia can be diagnosed through a variety of tests, including electrocardiograms (ECGs), stress tests, and imaging studies such as echocardiography or cardiac magnetic resonance imaging (MRI). Treatment options for myocardial ischemia include medications such as nitrates, beta blockers, and calcium channel blockers, as well as lifestyle changes such as quitting smoking, losing weight, and exercising regularly. In severe cases, surgical procedures such as coronary artery bypass grafting or angioplasty may be necessary.

Some common examples of respiratory tract diseases include:

1. Pneumonia: An infection of the lungs that can be caused by bacteria, viruses, or fungi.
2. Bronchitis: Inflammation of the airways (bronchi) that can cause coughing, wheezing, and difficulty breathing.
3. Asthma: A chronic condition that causes inflammation and narrowing of the airways, leading to symptoms such as wheezing, coughing, and shortness of breath.
4. Chronic obstructive pulmonary disease (COPD): A progressive condition that makes it difficult to breathe due to damage to the lungs over time.
5. Tuberculosis: An infectious disease caused by the bacteria Mycobacterium tuberculosis that primarily affects the lungs.
6. Laryngitis: Inflammation of the voice box (larynx) that can cause hoarseness and difficulty speaking.
7. Tracheitis: Inflammation of the trachea, or windpipe, that can cause coughing, fever, and difficulty breathing.
8. Croup: An infection of the throat and lungs that can cause a barky cough and difficulty breathing.
9. Pleurisy: Inflammation of the lining around the lungs (pleura) that can cause chest pain, fever, and difficulty breathing.
10. Pertussis (whooping cough): An infectious disease caused by the bacteria Bordetella pertussis that can cause coughing fits and difficulty breathing.

These are just a few examples of the many different types of respiratory tract diseases that exist. Each one has its own unique symptoms, causes, and treatment options.

Types of Kidney Diseases:

1. Acute Kidney Injury (AKI): A sudden and reversible loss of kidney function that can be caused by a variety of factors, such as injury, infection, or medication.
2. Chronic Kidney Disease (CKD): A gradual and irreversible loss of kidney function that can lead to end-stage renal disease (ESRD).
3. End-Stage Renal Disease (ESRD): A severe and irreversible form of CKD that requires dialysis or a kidney transplant.
4. Glomerulonephritis: An inflammation of the glomeruli, the tiny blood vessels in the kidneys that filter waste products.
5. Interstitial Nephritis: An inflammation of the tissue between the tubules and blood vessels in the kidneys.
6. Kidney Stone Disease: A condition where small, hard mineral deposits form in the kidneys and can cause pain, bleeding, and other complications.
7. Pyelonephritis: An infection of the kidneys that can cause inflammation, damage to the tissues, and scarring.
8. Renal Cell Carcinoma: A type of cancer that originates in the cells of the kidney.
9. Hemolytic Uremic Syndrome (HUS): A condition where the immune system attacks the platelets and red blood cells, leading to anemia, low platelet count, and damage to the kidneys.

Symptoms of Kidney Diseases:

1. Blood in urine or hematuria
2. Proteinuria (excess protein in urine)
3. Reduced kidney function or renal insufficiency
4. Swelling in the legs, ankles, and feet (edema)
5. Fatigue and weakness
6. Nausea and vomiting
7. Abdominal pain
8. Frequent urination or polyuria
9. Increased thirst and drinking (polydipsia)
10. Weight loss

Diagnosis of Kidney Diseases:

1. Physical examination
2. Medical history
3. Urinalysis (test of urine)
4. Blood tests (e.g., creatinine, urea, electrolytes)
5. Imaging studies (e.g., X-rays, CT scans, ultrasound)
6. Kidney biopsy
7. Other specialized tests (e.g., 24-hour urinary protein collection, kidney function tests)

Treatment of Kidney Diseases:

1. Medications (e.g., diuretics, blood pressure medication, antibiotics)
2. Diet and lifestyle changes (e.g., low salt intake, increased water intake, physical activity)
3. Dialysis (filtering waste products from the blood when the kidneys are not functioning properly)
4. Kidney transplantation ( replacing a diseased kidney with a healthy one)
5. Other specialized treatments (e.g., plasmapheresis, hemodialysis)

Prevention of Kidney Diseases:

1. Maintaining a healthy diet and lifestyle
2. Monitoring blood pressure and blood sugar levels
3. Avoiding harmful substances (e.g., tobacco, excessive alcohol consumption)
4. Managing underlying medical conditions (e.g., diabetes, high blood pressure)
5. Getting regular check-ups and screenings

Early detection and treatment of kidney diseases can help prevent or slow the progression of the disease, reducing the risk of complications and improving quality of life. It is important to be aware of the signs and symptoms of kidney diseases and seek medical attention if they are present.

There are several symptoms of RA, including:

1. Joint pain and stiffness, especially in the hands and feet
2. Swollen and warm joints
3. Redness and tenderness in the affected areas
4. Fatigue, fever, and loss of appetite
5. Loss of range of motion in the affected joints
6. Firm bumps of tissue under the skin (rheumatoid nodules)

RA can be diagnosed through a combination of physical examination, medical history, blood tests, and imaging studies such as X-rays or ultrasound. Treatment typically involves a combination of medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs), and biologic agents. Lifestyle modifications such as exercise and physical therapy can also be helpful in managing symptoms and improving quality of life.

There is no cure for RA, but early diagnosis and aggressive treatment can help to slow the progression of the disease and reduce symptoms. With proper management, many people with RA are able to lead active and fulfilling lives.

Cocarcinogenesis can occur through various mechanisms, such as:

1. Synergistic effects: The combined effect of two or more substances is greater than the sum of their individual effects. For example, smoking and exposure to asbestos can increase the risk of lung cancer more than either factor alone.
2. Antagonism: One substance may counteract the protective effects of another substance, leading to an increased risk of cancer. For example, alcohol consumption may antagonize the protective effects of a healthy diet against liver cancer.
3. Potentiation: One substance may enhance the carcinogenic effects of another substance. For example, smoking can potentiate the carcinogenic effects of exposure to certain chemicals in tobacco smoke.
4. Multistage carcinogenesis: Cocarcinogens can contribute to the development of cancer through multiple stages of carcinogenesis, including initiation, promotion, and progression.

Understanding cocarcinogenesis is important for developing effective cancer prevention strategies and for identifying potential co-carcinogens in our environment and diet. By identifying and avoiding co-carcinogens, we can reduce our risk of cancer and improve our overall health.

There are two main types of heart failure:

1. Left-sided heart failure: This occurs when the left ventricle, which is the main pumping chamber of the heart, becomes weakened and is unable to pump blood effectively. This can lead to congestion in the lungs and other organs.
2. Right-sided heart failure: This occurs when the right ventricle, which pumps blood to the lungs, becomes weakened and is unable to pump blood effectively. This can lead to congestion in the body's tissues and organs.

Symptoms of heart failure may include:

* Shortness of breath
* Fatigue
* Swelling in the legs, ankles, and feet
* Swelling in the abdomen
* Weight gain
* Coughing up pink, frothy fluid
* Rapid or irregular heartbeat
* Dizziness or lightheadedness

Treatment for heart failure typically involves a combination of medications and lifestyle changes. Medications may include diuretics to remove excess fluid from the body, ACE inhibitors or beta blockers to reduce blood pressure and improve blood flow, and aldosterone antagonists to reduce the amount of fluid in the body. Lifestyle changes may include a healthy diet, regular exercise, and stress reduction techniques. In severe cases, heart failure may require hospitalization or implantation of a device such as an implantable cardioverter-defibrillator (ICD) or a left ventricular assist device (LVAD).

It is important to note that heart failure is a chronic condition, and it requires ongoing management and monitoring to prevent complications and improve quality of life. With proper treatment and lifestyle changes, many people with heart failure are able to manage their symptoms and lead active lives.

Benign ovarian neoplasms include:

1. Serous cystadenoma: A fluid-filled sac that develops on the surface of the ovary.
2. Mucinous cystadenoma: A tumor that is filled with mucin, a type of protein.
3. Endometrioid tumors: Tumors that are similar to endometrial tissue (the lining of the uterus).
4. Theca cell tumors: Tumors that develop in the supportive tissue of the ovary called theca cells.

Malignant ovarian neoplasms include:

1. Epithelial ovarian cancer (EOC): The most common type of ovarian cancer, which arises from the surface epithelium of the ovary.
2. Germ cell tumors: Tumors that develop from germ cells, which are the cells that give rise to eggs.
3. Stromal sarcomas: Tumors that develop in the supportive tissue of the ovary.

Ovarian neoplasms can cause symptoms such as pelvic pain, abnormal bleeding, and abdominal swelling. They can also be detected through pelvic examination, imaging tests such as ultrasound and CT scan, and biopsy. Treatment options for ovarian neoplasms depend on the type, stage, and location of the tumor, and may include surgery, chemotherapy, and radiation therapy.

Some common examples of intraoperative complications include:

1. Bleeding: Excessive bleeding during surgery can lead to hypovolemia (low blood volume), anemia (low red blood cell count), and even death.
2. Infection: Surgical wounds can become infected, leading to sepsis or bacteremia (bacterial infection of the bloodstream).
3. Nerve damage: Surgery can sometimes result in nerve damage, leading to numbness, weakness, or paralysis.
4. Organ injury: Injury to organs such as the liver, lung, or bowel can occur during surgery, leading to complications such as bleeding, infection, or organ failure.
5. Anesthesia-related complications: Problems with anesthesia can include respiratory or cardiac depression, allergic reactions, or awareness during anesthesia (a rare but potentially devastating complication).
6. Hypotension: Low blood pressure during surgery can lead to inadequate perfusion of vital organs and tissues, resulting in organ damage or death.
7. Thromboembolism: Blood clots can form during surgery and travel to other parts of the body, causing complications such as stroke, pulmonary embolism, or deep vein thrombosis.
8. Postoperative respiratory failure: Respiratory complications can occur after surgery, leading to respiratory failure, pneumonia, or acute respiratory distress syndrome (ARDS).
9. Wound dehiscence: The incision site can separate or come open after surgery, leading to infection, fluid accumulation, or hernia.
10. Seroma: A collection of serous fluid that can develop at the surgical site, which can become infected and cause complications.
11. Nerve damage: Injury to nerves during surgery can result in numbness, weakness, or paralysis, sometimes permanently.
12. Urinary retention or incontinence: Surgery can damage the bladder or urinary sphincter, leading to urinary retention or incontinence.
13. Hematoma: A collection of blood that can develop at the surgical site, which can become infected and cause complications.
14. Pneumonia: Inflammation of the lungs after surgery can be caused by bacteria, viruses, or fungi and can lead to serious complications.
15. Sepsis: A systemic inflammatory response to infection that can occur after surgery, leading to organ dysfunction and death if not treated promptly.

It is important to note that these are potential complications, and not all patients will experience them. Additionally, many of these complications are rare, and the vast majority of surgeries are successful with minimal or no complications. However, it is important for patients to be aware of the potential risks before undergoing surgery so they can make an informed decision about their care.

There are several types of chromosome aberrations, including:

1. Chromosomal deletions: Loss of a portion of a chromosome.
2. Chromosomal duplications: Extra copies of a chromosome or a portion of a chromosome.
3. Chromosomal translocations: A change in the position of a chromosome or a portion of a chromosome.
4. Chromosomal inversions: A reversal of a segment of a chromosome.
5. Chromosomal amplifications: An increase in the number of copies of a particular chromosome or gene.

Chromosome aberrations can be detected through various techniques, such as karyotyping, fluorescence in situ hybridization (FISH), or array comparative genomic hybridization (aCGH). These tests can help identify changes in the chromosomal makeup of cells and provide information about the underlying genetic causes of disease.

Chromosome aberrations are associated with a wide range of diseases, including:

1. Cancer: Chromosome abnormalities are common in cancer cells and can contribute to the development and progression of cancer.
2. Birth defects: Many birth defects are caused by chromosome abnormalities, such as Down syndrome (trisomy 21), which is caused by an extra copy of chromosome 21.
3. Neurological disorders: Chromosome aberrations have been linked to various neurological disorders, including autism and intellectual disability.
4. Immunodeficiency diseases: Some immunodeficiency diseases, such as X-linked severe combined immunodeficiency (SCID), are caused by chromosome abnormalities.
5. Infectious diseases: Chromosome aberrations can increase the risk of infection with certain viruses, such as human immunodeficiency virus (HIV).
6. Ageing: Chromosome aberrations have been linked to the ageing process and may contribute to the development of age-related diseases.
7. Radiation exposure: Exposure to radiation can cause chromosome abnormalities, which can increase the risk of cancer and other diseases.
8. Genetic disorders: Many genetic disorders are caused by chromosome aberrations, such as Turner syndrome (45,X), which is caused by a missing X chromosome.
9. Rare diseases: Chromosome aberrations can cause rare diseases, such as Klinefelter syndrome (47,XXY), which is caused by an extra copy of the X chromosome.
10. Infertility: Chromosome abnormalities can contribute to infertility in both men and women.

Understanding the causes and consequences of chromosome aberrations is important for developing effective treatments and improving human health.

Developmental disabilities can include a wide range of diagnoses, such as:

1. Autism Spectrum Disorder (ASD): A neurological disorder characterized by difficulties with social interaction, communication, and repetitive behaviors.
2. Intellectual Disability (ID): A condition in which an individual's cognitive abilities are below average, affecting their ability to learn, reason, and communicate.
3. Down Syndrome: A genetic disorder caused by an extra copy of chromosome 21, characterized by intellectual disability, delayed speech and language development, and a distinctive physical appearance.
4. Cerebral Palsy (CP): A group of disorders that affect movement, balance, and posture, often resulting from brain injury or abnormal development during fetal development or early childhood.
5. Attention Deficit Hyperactivity Disorder (ADHD): A neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity, and impulsivity.
6. Learning Disabilities: Conditions that affect an individual's ability to learn and process information, such as dyslexia, dyscalculia, and dysgraphia.
7. Traumatic Brain Injury (TBI): An injury to the brain caused by a blow or jolt to the head, often resulting in cognitive, emotional, and physical impairments.
8. Severe Hearing or Vision Loss: A condition in which an individual experiences significant loss of hearing or vision, affecting their ability to communicate and interact with their environment.
9. Multiple Disabilities: A condition in which an individual experiences two or more developmental disabilities simultaneously, such as intellectual disability and autism spectrum disorder.
10. Undiagnosed Developmental Delay (UDD): A condition in which an individual experiences delays in one or more areas of development, but does not meet the diagnostic criteria for a specific developmental disability.

These conditions can have a profound impact on an individual's quality of life, and it is important to provide appropriate support and accommodations to help them reach their full potential.

Examples of communicable diseases include:

1. Influenza (the flu)
2. Measles
3. Tuberculosis (TB)
4. HIV/AIDS
5. Malaria
6. Hepatitis B and C
7. Chickenpox
8. Whooping cough (pertussis)
9. Meningitis
10. Pneumonia

Communicable diseases can be spread through various means, including:

1. Direct contact with an infected person: This includes touching, hugging, shaking hands, or sharing food and drinks with someone who is infected.
2. Indirect contact with contaminated surfaces or objects: Pathogens can survive on surfaces for a period of time and can be transmitted to people who come into contact with those surfaces.
3. Airborne transmission: Some diseases, such as the flu and TB, can be spread through the air when an infected person talks, coughs, or sneezes.
4. Infected insect or animal bites: Diseases such as malaria and Lyme disease can be spread through the bites of infected mosquitoes or ticks.

Prevention and control of communicable diseases are essential to protect public health. This includes:

1. Vaccination: Vaccines can prevent many communicable diseases, such as measles, mumps, and rubella (MMR), and influenza.
2. Personal hygiene: Frequent handwashing, covering the mouth when coughing or sneezing, and avoiding close contact with people who are sick can help prevent the spread of diseases.
3. Improved sanitation and clean water: Proper disposal of human waste and adequate water treatment can reduce the risk of disease transmission.
4. Screening and testing: Identifying and isolating infected individuals can help prevent the spread of disease.
5. Antibiotics and antiviral medications: These drugs can treat and prevent some communicable diseases, such as bacterial infections and viral infections like HIV.
6. Public education: Educating the public about the risks and prevention of communicable diseases can help reduce the spread of disease.
7. Contact tracing: Identifying and monitoring individuals who have been in close contact with someone who has a communicable disease can help prevent further transmission.
8. Quarantine and isolation: Quarantine and isolation measures can be used to control outbreaks by separating infected individuals from those who are not infected.
9. Improved healthcare infrastructure: Adequate healthcare facilities, such as hospitals and clinics, can help diagnose and treat communicable diseases early on, reducing the risk of transmission.
10. International collaboration: Collaboration between countries and global organizations is crucial for preventing and controlling the spread of communicable diseases that are a threat to public health worldwide, such as pandemic flu and SARS.

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A flood risk assessment (FRA) is an assessment of the risk of flooding from all flooding mechanisms, the identification of ... A flood risk assessment should be an evaluation of the flood risk and the consequences and impact and vulnerability. Non- ... In exceptional cases a FRA can be completed to justify development in flood risk areas. Advice on flood risk assessment is ... consisting of a flood risk assessment. Flood warning Floods directive Flood Modeller (software used to undertake flood risk ...
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An essential part of a risk assessment is the dose-response assessment. This is an evaluation that determines the correlation ... The final step of an occupational risk assessment is risk characterization. This is where the data gathered is combined to ... An occupational risk assessment is an evaluation of how much potential danger a hazard can have to a person in a workplace ... Occupational risk assessments are only estimations and must be done in a logical coherent fashion using probability. Due to an ...
Quantitative risk assessment (QRA) software and methodologies give quantitative estimates of risks, given the parameters ... Impact assessment, Occupational safety and health, Probability assessment, Risk analysis software). ... In financial terms, quantitative risk assessments include a calculation of the single loss expectancy of monetary value of an ... NATIONAL MINERALS INDUSTRY SAFETY AND HEALTH RISK ASSESSMENT GUIDELINE, Joy J & Griffiths D, 2007, p. 61 (Evaluation methods, ...
In England and Wales, Strategic Flood Risk Assessments (SFRAs) are a required part of the local planning process, as set out in ... On the smaller scale these SFRAs are used to inform site-specific Flood Risk Assessments (FRAs) for individual planning ... At the regional level, the equivalent document is the Regional Flood Risk Appraisal. ... "form the basis for preparing appropriate policies for flood risk management" at the local level. ...
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DREAD is part of a system for risk-assessing computer security threats that was formerly used at Microsoft. It provides a ... mnemonic for risk rating security threats using five categories. The categories are: Damage - how bad would an attack be? ...
In the context of food and feed safety, risk assessment is taken to mean a risk-oriented assessment with the aim of ... Risk assessment, risk management and risk communication are legally (Regulation (EC) No. 178/2002) separate activities. In ... in place relating to a certain risk. To ensure that the assessment principles of the health-related risk assessments are ... So risk assessment and risk management are legally separate activities (Regulation (EC) No. 178/2002). The BfR has more than ...
... is a bimonthly peer-reviewed scientific journal covering risk analysis as it relates to ... Risk analysis, Environmental health journals, Ecology journals, Taylor & Francis academic journals, Publications established in ...
... underwriting risk, market risk, counterparty default risk, operational risk, intangible asset risk - but also other risks ... risk management framework Insurer assessment of risk exposures Group risk capital and prospective solvency assessment Solvency ... The risk appetite The risk tolerances The risk appetite is the maximum aggregated level of risk that a company wishes to take. ... business risk, strategic risk, reputation risk, etc.. Once the mapping is done, a metric must be defined to quantify the risks ...
Risk assessment involves two parts: risk analysis and risk evaluation, although the term "risk assessment" can be seen used ... and fault trees are few examples of how network theories can be applied in risk assessment. In epidemiology risk assessments ( ... Risk assessment is a method for dealing with uncertainty. For it to be beneficial to the overall risk management and decision ... "Chapter 5 Risk Management." Risk Assessment: Theory, Methods, and Applications. Hoboken, NJ: John Wiley & Sons, 2011. p.117-36 ...
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It was created with the purpose to obtain and improved approach to support the risk assessment of influenza viruses with ... TIPRA was modelled after the Influenza Risk Assessment Tool (IRAT), an evaluation tool developed by the U.S. Centers for ... The Tool for Influenza Pandemic Risk Assessment (TIPRA), is a tool developed by the World Health Organization's Global ... Global Influenza Surveillance and Response System Burke, Stephen A.; Trock, Susan C. (2018). "Use of Influenza Risk Assessment ...
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... not based on a risk assessment) when the relevant scientific evidence is insufficient. Risk assessment is defined in para4 of ... "risk management", which takes into account the result of the risk assessment in addition to the social values and politics. ... SPS measures must be based on appropriate assessments of the risks to human, animal or plant life or health. The risk ... Risk assessment represents a quantitative or qualitative estimate of the possible "harmful effect of the intake of or exposure ...
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Intimate Partner Violence Risk Assessment Validation Study. U.S. Department of Justice. University of Wisconsin - Madison ... perception of risk of re-assault and risk of serious harm; captured relevant information equally well with victims of various ... To do less risks more. A variation of MAJ is now used by Sheriff's Deputies, bailiffs, and others tasked to protect judges and ... MOSAIC threat assessment systems (MOSAIC) is a method developed by Gavin de Becker and Associates in the early 1980s to assess ...
Multicriteria-based ranking for risk management of foodborne parasites. Microbiological Risk Assessment Series No. 23. FAO/WHO ... The operational definition of a food safety authority includes those authorities involved in: food policy; risk assessment; ... Microbiological risk assessment series 10. Archived from the original on April 2, 2015. Scallan E, Griffin PM, Angulo FJ, Tauxe ... "Reducing the risk from E. coli 0157 - controlling cross-contamination". Food Standards Agency, United Kingdom. February 2011. ...
The decision is made after a Multi Agency Risk Assessment Conference known as MARAC. In the case a parent who is not capable of ... It is the "manner" of acting that is important: is this activity being carried out safely after an appropriate risk assessment ... "Risk assessment". www.hse.gov.uk. Retrieved 20 September 2017. "Overarching Principles: Overarching Principles: Assaults on ... The assessment of capacity is used in a home based disability assessment under s.47 NHS and Community Care Act 1990. For a ...
II, Assessments and scientific basis for management options. U.S. Geological Survey. Retrieved February 16, 2017. Jardine, Jeff ... forcing the Corps to stop filling the lake or risk drowning him. Dubois hid in the canyon for five days while local authorities ... "Chapter 3: Central Valley Flood Management Systems" (PDF). Post-Flood Assessment for 1983, 1986, 1995, and 1997. Auburn Dam ...
The institute has also revamped its assessment structure from a percentage based to a CGPA based grading system. At research ... Dnyanajyoti Research Series (DJRS) is a research serial, which publishes occasional papers dealing with insurance and risk ... On 22 December 2007, National Assessment and Accreditation Council, an autonomous body of University Grants Commission (UGC), ... The PhD program revolves around Management, Insurance, Risk Management, Information Technology and Economics. The academy ...
"Two Tests Could Aid in Risk Assessment and Early Diagnosis of Alzheimer's", The New York Times, January 18, 2011. Accessed ...
"A Pilot Health Assessment of Exotic Dancers in San Francisco" A summer internship project conducted by current Executive ... This isolation puts sex workers at greater risk of occupational health and safety hazards that would otherwise be preventable. ... "Can the Decriminalization of Sex Work Assist HIV Prevention?" Sex Worker Environmental Assessment Team(SWEAT) Study data ... stjamesinfirmary.org/wordpress/wp-content/uploads/2008/05/Evaluating-Podcast-Social-Media.pdf A Pilot Health Assessment of ...
... risk analyses based on the number of people at a specific location at a specific time), transportation origin-destination ... "Rapid and near Real-time Assessments of Population Displacement Using Mobile Phone Data Following Disasters: The 2015 Nepal ... using rapid and near real-time assessment of population displacement following the Nepal earthquake. Modelling epidemics - ...
During the construction of a thermal power station in Niigata in 1957, he considered the risk of soil liquefaction being caused ... "Onagawa genshiryokuhatudensyo niokeru tusunamihyouka/taisaku no keii nituite" (About the process of assessment and measures of ... "女川原子力発電所における津波評価・対策の経緯について (About the process of assessment and measures of tsunami at
Critics claim it carries the risks of other types of food aid, which include displacing imports and disruption of local markets ... Report of the Food Aid and Food Security Assessment: A Review of the Title II Development Food Aid Program (PDF), Washington, D ... Experience has shown that these transactions are also fraught with legal and financial risks. 2. Monetization is economically ... Experience has shown that monetization requires intensive management and is fraught with risks. Procurement, shipping, ...
Assessment and Management of Risk for Engineered Systems and Geohazards. 13 (1): 53-65. doi:10.1080/17499518.2018.1498524. van ... Assessment and Management of Risk for Engineered Systems and Geohazards. 13 (1): 53-65. doi:10.1080/17499518.2018.1498524. ... Assessment and Management of Risk for Engineered Systems and Geohazards. 16 (3): 518-535. doi:10.1080/17499518.2021.1952611. ( ... Risk Analysis. Wiley. 8 (1): 71-90. doi:10.1111/j.1539-6924.1988.tb01155.x. ISSN 0272-4332. Walker, W.E.; Harremoës, P.; ...
In January 2016, a court denied bail to Ammon and Ryan Bundy saying that they were "a flight risk and a danger to the community ... The FBI's Art Crime Team conducted an archaeological field assessment to determine if the Native American Graves Protection and ... A USFWS spokesperson said that the damage risked "the destruction and desecration of culturally significant Native American ...
25 of the Committee on the Rights of the Child, children are at great risk in the digital domain regarding their vulnerable and ... data protection impact assessments, age appropriate design, privacy by default and transparency. The politics of the empire are ... ISBN 978-1-4798-8890-0. Gee, J.P. (2017). Teaching, learning, literacy in our high-risk high-tech world: A framework for ... has been highlighted as a challenge in ensuring the burgeoning AI norms sufficiently consider unique opportunities and risks ...
... three as probable high-risk (26, 53, and 66), and 12 as low-risk (6, 11, 40, 42, 43, 44, 54, 61, 70, 72, 81, and CP6108). ... Health Technology Assessment. 4 (18): 1-73. doi:10.3310/hta4180. PMID 10932023. Karnon J, Peters J, Platt J, Chilcott J, ... Other risk factors include smoking, a weak immune system, birth control pills, starting sex at a young age, and having many ... Due to the possible risk of cancer spread to the lymph nodes in stage 1B cancers and some stage 1A cancers, the surgeon may ...
"Peer review of the pesticide risk assessment of the active substance maleic hydrazide". EFSA Journal. 14 (6). June 2016. doi: ...
... machine Expertise of the operator Fetal posture Obstetric sonography is useful in the assessment of the cervix in women at risk ... A short cervix preterm is associated with a higher risk for premature delivery: At 24 weeks' gestation, a cervix length of less ... Further, the shorter the cervix, the greater the risk. Cervical measurement on ultrasound also has been helpful to use ... 1996). "The Length of the Cervix and the Risk of spontaneous Premature Delivery". New England Journal of Medicine. 334 (9): 567 ...
ATS-P processes available information from these databases to develop a risk assessment for each traveler. The risk assessment ... "Privacy Impact Assessment, CBP Automated Targeting System" (PDF). Department of Homeland Security. Retrieved March 26, 2011. ... Against this backdrop, it is not surprising that various assessments of national security have concluded that the nation's ... receive additional screening prior to entry into or departure from the country because the traveler may pose a greater risk for ...
Their assessment was complete the following day and it was concluded that it was in fact a tornado that caused the most ... The highest risk of tornadoes was in eastern Pennsylvania where low-level wind shear and high Convective available potential ... However, a less thermodynamic environment in southern New York led to a lower risk around New York City. Around 11:00 a.m. EDT ... On July 25, 2010, the Storm Prediction Center (SPC) issued a slight risk for severe thunderstorms in the Tri-State Region, with ...
Davenport, Coral (2018-10-07). "Major Climate Report Describes a Strong Risk of Crisis as Early as 2040". The New York Times. ... Climate change assessment and attribution, Environmental reports, Intergovernmental Panel on Climate Change). ... A landmark report from the UN's Intergovernmental Panel on Climate Change warns policymakers of the risks ahead and the changes ... "High-latitude tundra and boreal forests are particularly at risk of climate change-induced degradation and loss, with woody ...
The aforementioned Global Assessment Report on Biodiversity and Ecosystem Services also suggested that a reduction in meat ... Boyle, Louise (22 February 2022). "US meat industry using 235m pounds of pesticides a year, threatening thousands of at-risk ... The 2019 IPBES Global Assessment Report on Biodiversity and Ecosystem Services found that the primary driver of biodiversity ...
A 2016 study finds that "oil production, oil reserves, oil dependence, and oil exports are associated with a higher risk of ... "Gender and Growth Assessment: Macroeconomic study. Research Report." Report produced for the Department for International ... One study finds the mere discovery (as opposed to just the exploitation) of petroleum resources increases the risk of conflict ... Responsible use of financial hedges can mitigate this risk to some extent.[citation needed] Susceptibility to this volatility ...
Liu Jingzhen has characterized him as self-confident and self-reliant, but I think a more accurate assessment would be arrogant ... While most candidates were men of certain means, those from poor families risked everything on passing the exams. Ambitious and ... After they give regular examinations to students, they rely on self-serving assessment of student performance to decide who ...
The website was updated after protests and now holds that no such risk has been found in recent, well-designed studies. The ... Biden's removal of Betsy Weatherhead from her role as director of the National Climate Assessment has been criticized as being ... "Scientific Integrity at Risk: The Food and Drug Administration" (PDF). Union of Concerned Scientists. Archived from the ... Pregnancy interruption as a risk factor in tumor incidence". Am J Pathol. 100 (2): 505-506. PMC 1903536. PMID 6773421. "In ...
... perceived risk and time pressure. Considering the situation within the context of the task under assessment, the panel are ... Perceived risk and feedback are deemed to be of greatest importance, twice as much as training and procedures, which these two ... Definition of situations and subsets Upon selection of a relevant panel of experts who will carry out the assessment, these ... Success Likelihood Index Method (SLIM) is a technique used in the field of Human reliability Assessment (HRA), for the purposes ...
At home on disability, he risks adopting a "sick role" that ends up depriving him of the estimable therapeutic value of work. ... The CAPS is the gold standard in PTSD assessment. Watson, P.; McFall, M.; McBrine, C.; Schnurr, P. P.; Friedman, M. J.; Keane, ... An Act To amend and modify the War Risk Insurance Act, ch. 16, 41 Stat. 371, 373 (1919) ("A schedule of ratings of reductions ... You ought to go.' Harbaugh, Ken (June 1, 2015). "The Risk of Over-Thanking Our Veterans". The New York Times. Archived from the ...
Management Audit is an assessment of methods and policies of an organization's management in the administration and the use of ... L Audit Internal audit Risk-based auditing Arter, Dennis R. (2000-01-04). "Management Audit". Qualitydigest.com. Retrieved 2013 ...
Assessment and Selection in Organizations, International Handbook of Selection and Assessment. Wiley. pp. 455-473. ISBN 978-0- ... For instance, their irresponsibility may be misconstrued by interviewers as risk-taking or entrepreneurial spirit. Their thrill ... "Towards an Integrated Analysis of Bias in Cross-Cultural Assessment" (PDF). European Journal of Psychological Assessment. 13 (1 ... This type of interview can be used for selection, promotion, or assessment of team skills. Interviewers may also use a group ...
... government in accordance with guidelines spelled out under the Federal Risk and Authorization Management Program (FedRAMP), a U ... government program that provides a standardized approach to security assessment, authorization, and continuous monitoring for ...
One of the risks of LNG is a rapid phase transition explosion (RPT), which occurs when cold LNG comes into contact with water. ... "Dominion welcomes FERC assessment of Cove Point LNG". lngindustry.com. July 28, 2014. Archived from the original on July 28, ... "LNG: Benefits and Risks of Liquified Natural Gas". Archived from the original on 2013-08-08. Retrieved 2013-02-25. "lng ... If this mixture is within the flammable range, there is risk of ignition, which would create fire and thermal radiation hazards ...
Level II characterizes stream type by using numbers 1 - 6, in addition to letters A - G, to include the assessments of the ... acceptance of the risk of classifying streams incorrectly, and (3) classification results may be used inappropriately Rosgen, ... Level II is a quantitative morphological assessment of the stream reach which provides greater detail from data collected in ...
Center for Environmental Risk Assessment. "GM Crop Database:Tomato". International Life Sciences Institute. Archived from the ... Specifically, there was no evidence for health risks, and the nutritional content was unchanged. According to the existing ... Safety Assessment of Genetically Engineered Fruits and Vegetables: A Case Study of the Flavr Savr Tomato. CRC Press. p. 288.{{ ...
Another risk of these powerful magnets is that if more than one magnet is ingested, they can pinch soft tissues in the ... Scenario assessment of neodymium recycling in Japan based on substance flow analysis and future demand forecast. J Mater Cycles ...
The identification and assessment of assumptions solves this problem and forms the foundation for managing new business ... Discovery Driven Growth: A Breakthrough Process to Reduce Risk and Seize Opportunity. Boston: Harvard Business Publishing ... Important parts of the business plan to check are the definition of the business concept and an assessment of the competition. ... The continuous process consists of six steps: Knowledge Base Assessment, Critical Assumption Planning, Test Program Design, ...
Read the risk assessment CDC prepared about the new COVID-19 Variant BA2.86 being tracked. ... Current Risk Assessment. Based on what CDC knows now, existing tests used to detect and medications used to treat COVID-19 ... Risk Assessment Summary for SARS CoV-2 Sublineage BA.2.86. August 23, 2023, 10:10 AM EDT ... What follows is a scientific assessment of BA.2.86s risk profile based on what CDC knows now. ...
... cancer or who have an ancestry associated with BRCA1/2 gene mutations with an appropriate brief familial risk assessment tool. ... Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: a systematic review to update the U. ... Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force ... Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women: Updated Evidence Report and ...
Risk assessment -- RDoC Element. Type of Element: Behavior. The following construct(s)/subconstruct(s) refer to this element... ... Home , Research , Research Funded by NIMH , Research Domain Criteria (RDoC) , Units of Analysis , Behaviors , Risk assessment. ...
... few data exist on which specific bodily fluids are infected or on the risk of fomite transmission. Therefore, we tested various ... Assessment of the risk of Ebola virus transmission from bodily fluids and fomites Daniel G Bausch et al. J Infect Dis. 2007. . ... Assessment of the risk of Ebola virus transmission from bodily fluids and fomites Daniel G Bausch 1 , Jonathan S Towner, Scott ... We conclude that EBOV is shed in a wide variety of bodily fluids during the acute period of illness but that the risk of ...
... * Tracking Personal Exposures Over Time ... The infrastructure and decades of risk assessment expertise provided by UC Berkeley SRP Center researchers served as the ... and Medicine committee on risk assessment in the 21st century.. Smith and Lauren Zeise Ph.D., head of the Office of ... Since then, NTP has also used the approach in their cancer hazard assessment report on night shift work and light at night, ...
Cite this: Rabies Risk Assessment: Test Your Knowledge - Medscape - Aug 08, 2019. ... important milestones for rabies control and underscores the need for a campaign to raise public awareness about rabies risk.[3] ...
Violence Risk Assessment Tools. Risk assessment tools provide a standard against which to evaluate individuals for potential ... A danger assessment scale is helpful for ascertaining the risk of assault or homicide. The use of such a scale is important ... Danger Assessment Tool: to assess the risk to nurses and other healthcare personnel of an individual who is exhibiting signs of ... Note: This risk assessment tool was clinically tested and evaluated by community mental health clinicians and a sample of ...
Travel Risk Assessment. The DHS Office of Strategy, Policy, and Plans recently completed its evaluation and review of all ... The goal of the Travel Risk Assessment process is to keep Americans safe. As then-Acting Secretary Wolf noted during his 2020 ... Overview of the Travel Risk Assessment Process. PDF. 749.22 KB. 01/15/2021 ... DHS/PLCY continues to assess in real time the risk of COVID-19 infection from travelers arriving from foreign ports and makes ...
A generic risk assessment for people managing or using cryogenic materials ... The generic risk assessment can be adopted and adapted by departments or research groups or others using cryogenic materials in ... Line managers / PIs are responsible for making sure that the risk assessment is tailored to reflect the tasks and context in ... The Oxygen Depletion Calculator at the end of the risk assessment should be used to calculate the amount of cryogenic material ...
Risk assessments have direct impact among the occupational safety and health community, providing quantitative information on ... NIOSH work on risk assessment methods has had an impact on the field of risk assessment by expanding the methods available and ... Risk assessment methods development is a critical focus to provide the most statistically sound risk assessments. Methods to ... The Environmental Protection Agency (EPA) has also used NIOSH risk assessments to support environmental assessments. State ...
... complete the Event Risk Assessment form at least 30 days before your event. Please be comprehensive and descriptive with your ... Risk Management and Public Safety will review your event details and contact you to discuss it further. If there will be an ... If you are an OSE Recognized Student Organization who is hosting an event that involves risk, please schedule a meeting with ... During the meeting, Mary will review the risk and assist with the completion of the form. ...
guidance notes for risk assessment outlined in annex 3 of council directive 90/219/EEC on the contained use of genetically ... such that the risk assessment is no longer adequate, the risk assessment must be reviewed in the light of the changes. Any ... The assessment requires that the risk of these potentially harmful effects are considered for each activity and allocated to a ... The risk assessment process requires the identification of any potentially harmful properties of the GMM as a result of the ...
Assessment Questions. Historical Document. This document is provided by the Agency for Toxic Substances and Disease Registry ( ...
Estimates indicate that approximately one half of all cancer cases either arise from modifiable risk factors or can be detected ... Risk Assessment. Assessment of an individuals risk is a key step in cancer prevention; risk assessment programs have been ... Women with a lifetime risk of breast cancer estimated at 20% or greater according to family history-based risk assessment ... Practice Bulletin Number 179: Breast Cancer Risk Assessment and Screening in Average-Risk Women. Obstet Gynecol. 2017 Jul. 130 ...
Both scenario-based and probabilistic risk assessment are... ... practices in regional and portfolio seismic risk assessment, ... 16.2.2 Probabilistic Hazard/Risk Assessment. In a fully probabilistic risk assessment, where all possible and relevant ... is also of relevance for risk assessment.. In fact, the use of the term "deterministic" in current hazard and risk assessment ... The use of PSHA hazard maps is appropriate for site-specific risk assessment and maps which present the comparative risk at ...
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risk assessment Share to Facebook Share to Twitter Related Projects. Cybersecurity Supply Chain Risk Management C-SCRM. NEW! ... Privacy Risk Assessment: A Prerequisite for Privacy Risk Management. June 5, 2017 As part of an ongoing series of workshops on ... Cyber Supply Chain Risk Management (C-SCRM): Validating the Integrity of Server and Client Devices. September 10, 2019 On ... Cyber Security Assessment and Management (CSAM), Planning for Implementing SP 800-53, Revision 5. Presentation - May 26, 2021 ...
This activity encourages students to apply public policy and risk regulation concepts to the case of the Canterbury Earthquakes ... Risk Assessment and Regulation in Christchurch, New Zealand Risk Assessment and Regulation in Christchurch, New Zealand This ... risk regulation, risk assessment and management, and policy analysis and evaluation); ... The activity requires students to engage with the concept of risk in terms of understanding risk regulation (how can/does/ ...
Find caries risk assessment forms along with other helpful ADA resources valuable for the prevention and management of dental ... and appropriate risk assessment (detection and staging of lesions, assessment of caries activity, and caries risk assessment); ... Caries Risk Form (Patients Over 6 Years) (PDF). ADA Caries Risk Assessment Forms (For Dental Education Use Only). *Caries Risk ... Caries Risk Assessment Form (Age 0-6). Accessed May 27, 2021.. *American Dental Association. Caries Risk Assessment Form (Age , ...
Your message has been sent to our CLARA - Claims Risk Assessment team. ... Smart underwriting: 4 + 2 health questions suffice for in-depth risk assessment ... Improved risk result Structured data collection and a focused handling process help to avoid errors. ... Shorter assessment times have a positive impact on your companys reputation. The claims process is increasingly important in ...
Risk assessment has been most often applied in assessing the risk of carcinogens, often with animal bioassay data. However, ... In order to more accurately estimate risks to humans from exposures to toxic agents, it is important that risk assessment ... MECHANISTIC-BASED CANCER RISK ASSESSMENT METHODS Release Date: April 15, 1999 RFA: OH-99-003 P.T. National Institute for ... Risk assessment for noncarcinogens, particularly qualitative approaches, is even less well developed. Improved methods are ...
Risk Assessment. It must be appreciated that risk assessment is not a precise science. ... There are many systems that can be used to determine the risk associated with a hazard within the workplace. A simple and ... It is necessary, therefore, to quantify the risks in a way that is understandable and credible to all concerned. ...
NICEATM and partners developed a non-animal approach to evaluate ACD risk for isothiazolinones, which are used as ... Non-animal Risk Assessment for Isothiazolinones. In May 2020, EPA requested comment on draft human health and ecological risk ... The draft risk assessments rely heavily on work done by NTP, NICEATM, and ICCVAM. The in vitro testing was conducted by the NTP ... This is the first use of this type of defined approach in regulatory risk assessment. ...
A fall risk assessment helps find out how likely it is that you will fall. It is mostly done for adults 65 years or older. ... Are there any risks to a fall risk assessment?. There is a small risk that you may fall as you do the assessment. ... A fall risk assessment is used to find out if you have a low, moderate, or high risk of falling. If the assessment shows you ... medlineplus.gov/lab-tests/fall-risk-assessment/ Fall Risk Assessment. ...
Uncertainty and Variability Characterization and Measures in Risk Assessment.. Understanding Large-Scale Structure in Massive ... Home » MAA Publications » MAA Reviews » Encyclopedia of Quantitative Risk Analysis and Assessment ... From Basel II to Solvency II - Risk Management in the Insurance Sector. ... Mathematics of Risk and Reliability: A Select History.. Mercury/Methylmercury Risk.. Meta-Analysis in Clinical Risk Assessment. ...
A54978 - Response to Comments: MolDX: Biomarkers in Cardiovascular Risk Assessment LCDs. DL36318 - (MCD Archive Site) DL36358 ... Page Help for Article - Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment (A57037). ... Biomarkers in Cardiovascular Risk Assessment LCD and placed in this article. ...
The framework draws on a standard VaR type framework used to assess various types of stability risk and can be easily applied ... This paper presents a novel documentation of cyber risk around the world for financial institutions by analyzing the different ... The other novel contribution that is outlined is a quantitative framework to assess cyber risk for the financial sector. ... Cyber risk has emerged as a key threat to financial stability, following recent attacks on financial institutions. ...
... risk assessments, risk management, cyber security program, security risk assessment , Yokogawa Belgium (NL) ...
2004)‎. IPCS risk assessment terminology. World Health Organization. https://extranet.who.int/iris/restricted/handle/10665/ ...
  • Both scenario-based and probabilistic risk assessment are addressed, and modelling practices in the hazard, fragility/vulnerability and exposure components are presented and critiqued. (springer.com)
  • The Environmental Protection Agency (EPA) has also used NIOSH risk assessments to support environmental assessments. (cdc.gov)
  • NIOSH risk assessments support NIOSH authoritative recommendations to reduce hazardous exposures to workers. (cdc.gov)
  • The Occupational Safety and Health Administration (OSHA) has incorporated NIOSH risk assessments into workplace standards. (cdc.gov)
  • State agencies and other entities setting occupational exposure limits have used NIOSH recommendations based on risk assessments. (cdc.gov)
  • NIOSH work on risk assessment methods has had an impact on the field of risk assessment by expanding the methods available and better characterizing exposure-response model uncertainty. (cdc.gov)
  • In the 1st European Conference on Earthquake Engineering and Seismology in Geneva in 2006, a keynote paper was presented by Norman Abrahamson on "Seismic hazard assessment: problems with current practice and future developments" (Abrahamson 2006 ). (springer.com)
  • Abrahamson reviewed areas within the practice of probabilistic seismic hazard assessment (PSHA) that needed improvement and made recommendations on the direction that future research in PSHA should take. (springer.com)
  • Abrahamson ( 2006 ) summarised both deterministic and probabilistic approaches to hazard assessment, and outlined many of the misunderstandings related to these two approaches. (springer.com)
  • Abrahamson's focus was on hazard input for design and assessment, whereas herein we are interested in the hazard input for risk assessment of distributed assets. (springer.com)
  • In fact, the use of the term "deterministic" in current hazard and risk assessment practice is misleading as it implies that there is no uncertainty involved in the process. (springer.com)
  • There are many systems that can be used to determine the risk associated with a hazard within the workplace. (aberdeenshire.gov.uk)
  • Depending on the worker's level of experience and the degree of potential hazard associated with the proposed experiment, it may be necessary to obtain the assistance of supervisors and safety professionals before proceeding with risk assessment. (wpi.edu)
  • Cumulative Risk Assessment for Environmental Hazards. (maa.org)
  • to assess the risk to nurses and other healthcare personnel of an individual who is exhibiting signs of potentially dangerous behavior. (cdc.gov)
  • Explanation notation]The Danger Assessment is a clinical and research instrument that has been designed to help battered women assess their danger of homicide. (nih.gov)
  • DHS/PLCY continues to assess in real time the risk of COVID-19 infection from travelers arriving from foreign ports and makes appropriate recommendations. (dhs.gov)
  • This will drive targeted development of your business, give you a better understanding of incidence rates and allow you to assess risks in a more sophisticated manner. (munichre.com)
  • The other novel contribution that is outlined is a quantitative framework to assess cyber risk for the financial sector. (imf.org)
  • The framework draws on a standard VaR type framework used to assess various types of stability risk and can be easily applied at the individual country level. (imf.org)
  • This module will help you to assess risk, which is one of the key roles of a Club and Event Rowing Safety Adviser. (britishrowing.org)
  • The following outline provides a summary of the steps that laboratory workers should use to assess the risks of handling toxic chemicals. (wpi.edu)
  • Nevertheless, the key message that Abrahamson put forward - that both deterministic and probabilistic approaches result in probabilistic statements about the ground motion - is also of relevance for risk assessment. (springer.com)
  • Approaches for risk assessment have been developed for nonnutrients such as drugs, food additives, and pesticides, but approaches for risk assessment have received less attention in the nutrition area. (nih.gov)
  • Adapting and developing risk assessment strategies for application in nutrition science could lead to improved approaches to the development of dietary and nutritional recommendations and thus is a topic of considerable interest. (nih.gov)
  • How can the perspectives and methods of these diverse fields be brought together to develop more effective approaches for quantitative nutritional risk assessment? (nih.gov)
  • With this in mind, various experts presented information on a range of methodological challenges of nutritional risk assessment and on approaches that might be used to address the challenges. (nih.gov)
  • Risk assessment tools provide a standard against which to evaluate individuals for potential violence, enabling all healthcare providers to share a common frame of reference and understanding. (cdc.gov)
  • EPA requested comment on the use of an in vitro and artificial neural network-based defined approach instead of using laboratory animal data to evaluate skin sensitization risks for products containing isothiazolinones. (nih.gov)
  • These issues connect to geoscience because regulators and communities often depend on scientists and experts to help evaluate potential risks. (carleton.edu)
  • The flood risk assessment is intended to evaluate the integrity of the existing dike system and to determine whether the original design criteria apply to current and future flood levels. (citywindsor.ca)
  • Comparative Risk Assessment. (maa.org)
  • Comprehensive framework for comparative risk assessment in the energy sector. (psi.ch)
  • The comparative risk assessment of energy accidents has also progressed in terms of methodological developments and novel case study applications. (psi.ch)
  • Risk assessment methods development is a critical focus to provide the most statistically sound risk assessments. (cdc.gov)
  • Methods to improve risk assessment modeling and characterization of model uncertainty include model averaging and semi-parametric modeling. (cdc.gov)
  • MECHANISTIC-BASED CANCER RISK ASSESSMENT METHODS Release Date: April 15, 1999 RFA: OH-99-003 P.T. National Institute for Occupational Safety and Health National Center for Environmental Research and Quality Assurance National Cancer Institute Letter of Intent Receipt Date: May 26, 1999 Application Receipt Date: July 14, 1999 THIS RFA USES THE "MODULAR GRANT" AND "JUST-IN-TIME" CONCEPTS. (nih.gov)
  • PURPOSE The Centers for Disease Control and Prevention (CDC), the United States Environmental Protection Agency (EPA), and the National Institutes of Health, National Cancer Institute (NCI) announce the availability of fiscal year (FY) 1999 funds for grant applications for research related to mechanistic-based cancer risk assessment methods. (nih.gov)
  • Systematic methods of caries detection, classification, and risk assessment, as well as prevention/risk management strategies, can help to reduce patient risk of developing advanced disease and may even arrest the disease process. (ada.org)
  • Eligible Principal Investigators (PIs) should be an experienced senior level individual familiar ambulatory care delivery, patient safety, and with the use of risk assessment methods and approach or have such have expertise available as part of the project. (nih.gov)
  • As a step toward improving the communication and sharing methods and information across disciplines, members of the Interagency Risk Assessment Consortium, the U.S. Health and Human Services Office of the Assistant Secretary for Planning and Evaluation, the Institute of Medicine's Food Forum, and the International Life Sciences Institute planned the Nutritional Risk Assessment Workshop. (nih.gov)
  • The City of Windsor recently received funding approval to undertake a flood risk assessment for the study area along Riverside Drive East and inland, from St. Rose Beach easterly to the city limit with the Town of Tecumseh. (citywindsor.ca)
  • The City of Windsor retained Landmark Engineers Inc. in the fall of 2018 to undertake a flood risk assessment study for the East Riverside area. (citywindsor.ca)
  • to detect events early, the HIM Programme continuously monitor both indicator- and event-based surveillance sources and undertake risk assessments on priority events to guide a timely public health response to outbreaks and other emergencies. (who.int)
  • The risk assessment considers the exposure of humans or the environment to GMMs during the operation of, or possible unintended release from, a contained use facility. (hse.gov.uk)
  • Assessment of Risk Association with Beryllium Exposure. (maa.org)
  • Are the chemicals gases, or are they volatile enough to present a significant risk of exposure through inhalation? (wpi.edu)
  • Conduct methodological research for nutrition risk assessment. (nih.gov)
  • To conduct a risk assessment for a proposed event, complete the Event Risk Assessment form at least 30 days before your event. (ithaca.edu)
  • Within a short time of the claim being submitted, the claims handler uses CLARA to conduct a rule-based telephone interview for the purposes of assessment. (munichre.com)
  • Conduct a trial risk assessment of a single nutrient. (nih.gov)
  • The need to conduct vulnerability and risk assessments is being driven by these new laws and mandates. (informit.com)
  • When assessing workplace safety in the United States, we have to consider what measures of risk to use. (cdc.gov)
  • These declines have been attributed to risk reduction strategies, detection of early disease, and improvement in treatment strategies. (medscape.com)
  • The information in this article contains billing, coding or other guidelines that complement the Local Coverage Determination (LCD) for MolDX: Biomarkers in Cardiovascular Risk Assessment L36358. (cms.gov)
  • Risk assessments have direct impact among the occupational safety and health community, providing quantitative information on hazardous chemicals, of particular use to employers, workers, researchers, safety and health professionals, and standard- and recommendation-setting organizations. (cdc.gov)
  • Bayesian Statistics in Quantitative Risk Assessment. (maa.org)
  • Note: This risk assessment tool was clinically tested and evaluated by community mental health clinicians and a sample of clients in 6 catchment areas of Erie County, NY with a total population of 1.2 million, and approved that that county's Department of Mental Health for broad implementation. (cdc.gov)
  • The Danger Assessment has been used both clinically and in a research study with battered women. (nih.gov)
  • Environmental Risk Regulation. (maa.org)
  • risk assessment programs have been developed at many cancer centers to identify people who are at high risk. (medscape.com)
  • The Centers for Disease Control and Prevention (CDC) and the American Geriatric Society recommend yearly fall assessment screening for all adults 65 years of age and older. (medlineplus.gov)
  • NIEHS-funded University of California, Berkeley Superfund Research Program Center ( UC Berkeley SRP Center ) researchers and collaborators developed a new approach to help risk assessors predict the toxicity of chemicals based on shared characteristics. (nih.gov)
  • Called the key characteristics approach, the method helps risk assessors more easily identify, organize, and summarize the potential health risks of many different chemicals. (nih.gov)
  • How can they help overcome the data challenges that confront nutritional risk assessors? (nih.gov)
  • A danger assessment scale is helpful for ascertaining the risk of assault or homicide. (cdc.gov)
  • There are many danger assessment tools available for research, but clinicians need a quick manageable tool. (cdc.gov)
  • Results of this study, which give initial support for the reliability and validity of the Danger Assessment, are reported. (nih.gov)
  • The nurse and woman fill out and discuss the Danger Assessment together. (nih.gov)
  • The author recommends that this assessment for risk of homicide be part of the nursing assessments of battered women in all health care settings. (nih.gov)
  • If your provider recommends other assessments, he or she will let you know what to expect. (medlineplus.gov)
  • In this paper I take inspiration from Abrahamson, but will focus on the practice and development of probabilistic seismic risk assessment (PSRA), i.e. the estimation of the probability of damage and loss, for distributed buildings. (springer.com)
  • estimation of risk indicators for integration in future energy scenarios. (psi.ch)
  • In May 2020, EPA requested comment on draft human health and ecological risk assessments for a group of antimicrobial chemicals known as isothiazolinones. (nih.gov)
  • The draft risk assessments rely heavily on work done by NTP, NICEATM , and ICCVAM . (nih.gov)
  • This risk mitigation results in increased security and less probability of a threat or vulnerability impacting an organization's production environment. (informit.com)
  • Risk is the probability or likelihood of the occurrence or realization of a threat. (informit.com)
  • 2004)‎. IPCS risk assessment terminology. (who.int)
  • The classification level determined by the risk assessment defines the containment requirements for the activities involving GMMs in accordance with Annex IV. (hse.gov.uk)
  • Risk assessment is a valuable tool for the prevention and management of dental caries. (ada.org)
  • This paper looks at the current practices in regional and portfolio seismic risk assessment, discusses some of their shortcomings and presents proposals for improving the state-of-the-practice in the future. (springer.com)
  • For more than two decades, the practice of risk assessment has been applied to human public health issues, and policy makers have used the results of risk assessments in their decision-making process. (nih.gov)
  • Cyber risk has emerged as a key threat to financial stability, following recent attacks on financial institutions. (imf.org)
  • This paper presents a novel documentation of cyber risk around the world for financial institutions by analyzing the different types of cyber incidents (data breaches, fraud and business disruption) and identifying patterns using a variety of datasets. (imf.org)
  • That is why the Department, along with our interagency partners, developed a process for evaluating the information sharing cooperation, identity management practices and travel related risk associated with each country in the world. (dhs.gov)
  • Risk Management and Public Safety will review your event details and contact you to discuss it further. (ithaca.edu)
  • As part of an ongoing series of workshops on privacy engineering and risk management, NIST will host. (nist.gov)
  • Enterprise Risk Management (ERM). (maa.org)
  • From Basel II to Solvency II - Risk Management in the Insurance Sector. (maa.org)
  • The recent Federal Information Security Management Act (FISMA) is driving the need for vulnerability and risk assessments to be conducted for all United States federal government agencies. (informit.com)
  • The recent Canadian Management of Information Security Standard (MITS) requires regular security assessments for all Canadian federal government agencies. (informit.com)
  • The Oxygen Depletion Calculator at the end of the risk assessment should be used to calculate the amount of cryogenic material that could be released and impact on potential users of the space at the time of any release. (bath.ac.uk)
  • Therefore, risk models should be selected based on each individual's situation in order to calculate risk as accurately as possible. (medscape.com)
  • The goal of the Travel Risk Assessment process is to keep Americans safe. (dhs.gov)
  • These models allow for the incorporation of biological and mechanistic data into the risk assessment process. (astm.org)
  • These advances will not only improve the risk assessment process for halogenated solvents but will stimulate and guide basic research in the biological area. (astm.org)
  • The risk assessment process requires the identification of any potentially harmful properties of the GMM as a result of the genetic modification or any alteration of the recipient organisms' existing properties. (hse.gov.uk)
  • On average, such claims can take up to 200 days to process and often involve multiple requests for further information and convoluted assessment cycles - the scope for improvement is huge. (munichre.com)
  • Experience with the application of a risk assessment process to the setting of upper levels of intake for essential nutrients, for example, has uncovered a number of challenges. (nih.gov)
  • One nonscientific but overall challenge to nutritional risk assessment relates to increasing and improving communication among experts from key disciplines in ways that could inform the nutritional risk assessment process. (nih.gov)
  • This article will describe the literature supporting the danger of homicide for battered women, the development of the assessment instrument, the results of the research using the instrument, and suggestions for future use and research. (nih.gov)
  • The generic risk assessment can be adopted and adapted by departments or research groups or others using cryogenic materials in the course of their work. (bath.ac.uk)
  • Assessment with a nurse is conceptualized as a means of increasing the self-care agency of battered women, according to Orem's nursing conceptual framework.1 The instrument was used in a study of 79 battered women. (nih.gov)
  • For this purpose, the PSI's Technology Assessment group has developed a comprehensive and integrated framework for comparative accident risk assessment of energy systems (Figure 1) since the late 1990s. (psi.ch)
  • Cite this: Rabies Risk Assessment: Test Your Knowledge - Medscape - Aug 08, 2019. (medscape.com)
  • The overall approach, however, must be adapted and modified to take into account the unique aspects of nutrients, including the fact that both high and low nutrient intakes are associated with risk. (nih.gov)
  • The assessments and modeling will lead to the identification of preventable patient injuries/harm and inform the development and deployment of intervention strategies that eliminate, mitigate, or minimize those harms and threats in ambulatory care settings. (nih.gov)
  • Estimates indicate that approximately one half of all cancer cases either arise from modifiable risk factors or can be detected as precursor lesions before the development of disease with metastatic potential. (medscape.com)
  • A recent development in the cancer risk area is the advent of biologically based pharmacokinetic and pharmacodynamic models. (astm.org)
  • The ICCVAM Skin Sensitization Expert Group reviewed the NTP testing report and the NICEATM analyses before data were provided to EPA for development of the risk assessments. (nih.gov)
  • The elements of the risk assessment outlined in points 1 and 2 of Annex III requires consideration of potentially harmful effects to human health and the environment. (hse.gov.uk)
  • The degree of risk arising from contained uses with a genetically modified micro-organism (GMM), and their construction, is determined by consideration of the severity of the potential harmful effects, to human health or the environment, with the possibility of those effects occurring. (hse.gov.uk)
  • If the assessment shows you are at an increased risk, your health care provider and/or caregiver may recommend strategies to prevent falls and reduce the chance of injury. (medlineplus.gov)
  • Based on your results, your health care provider may make recommendations to reduce your risk of falling. (medlineplus.gov)
  • The program's components, with the exception of the announcement on risk assessment, have an emphasis on the role of health information technology (health IT). (nih.gov)
  • Environmental Health Risk. (maa.org)
  • Environmental Health Risk Assessment. (maa.org)
  • Environmental Health Triage, Chemical Risk Assessment for. (maa.org)
  • The Healthcare Information Privacy and Portability Act (HIPPA) is driving the need for vulnerability and risk assessments to be conducted within any health-care or health-care-related institution. (informit.com)
  • Through the Health Emergency Information and Risk Assessment (HIM) Programme area, WHO is committed to achieving one simple yet ambitious goal: to make the African Regional Office a reference point and source of knowledge for all public health emergencies in the African region. (who.int)
  • Does the experiment involve a significant risk of inadvertent ingestion or injection of chemicals? (wpi.edu)
  • The following memo from John Vandenberg, Director of EPA's National Center for Environmental Assessment, provides information regarding EPA's 2010 Integrated Risk Information System (IRIS) assessment of the air pollutant chloroprene. (epa.gov)
  • Some aspects of the risk assessment approach used for nonnutrients are applicable to the assessment of risks related to nutrition (called nutritional risk assessment in this workshop summary). (nih.gov)
  • Line managers / PI's are responsible for making sure that the risk assessment is tailored to reflect the tasks and context in which the work with cryogenic materials will be done. (bath.ac.uk)
  • work in the class focuses on evaluating and developing risk regulations and policy solutions. (carleton.edu)
  • Risk Of Homicide With Battered Women woman determine how much danger of homicide she is in by giving information about how many of the risk factors are present in the woman's relationship. (nih.gov)
  • Axiomatic Measures of Risk and Risk-Value Models. (maa.org)
  • The purpose of this Funding Opportunity Announcement (FOA) is to support proactive risk assessments and to model risks and known hazards that threaten patient safety in ambulatory care settings and in transitions of care. (nih.gov)
  • That assessment may change as additional scientific data are developed. (cdc.gov)
  • This assessment may change as additional data become available. (cdc.gov)
  • Although Ebola virus (EBOV) is transmitted by unprotected physical contact with infected persons, few data exist on which specific bodily fluids are infected or on the risk of fomite transmission. (nih.gov)
  • Urgent need for nutrition data suitable for risk assessment. (nih.gov)
  • By conducting a risk assessment and vulnerability assessment, an organization can uncover known weaknesses and vulnerabilities in its existing IT infrastructure, prioritize the impact of these vulnerabilities based on the value and importance of affected IT and data assets, and then implement the proper security controls and security countermeasures to mitigate those identified weaknesses. (informit.com)
  • In contrast, a simplified probabilistic safety assessment (PSA) is applied for nuclear , and evaluations of new renewables are based on a hybrid approach combining available data, modeling, and expert judgment. (psi.ch)
  • Cancer Risk Evaluation from Animal Studies. (maa.org)
  • Evaluation of Risk Communication Efforts. (maa.org)
  • A set of tasks, known as fall assessment tools. (medlineplus.gov)
  • The assessment includes performing a series of tasks called fall assessment tools. (medlineplus.gov)
  • Models of cancer risk have been developed to permit calculation of an individual's risk for a specific type of cancer. (medscape.com)
  • This is the first use of this type of defined approach in regulatory risk assessment. (nih.gov)
  • One of the best known of these is the Gail model, which predicts breast cancer risk on the basis of current age, race, age when menstruation began, age of first live birth, number of close relatives with breast cancer, number of breast biopsies, and the presence or absence of atypical hyperplasia on breast biopsies. (medscape.com)
  • [ 3 ] Like most cancer risk models, the Gail model has limitations: it does not include ovarian cancer history or breast cancer in second-degree relatives such as aunts, cousins, or grandparents. (medscape.com)
  • This model may also be less accurate in predicting risk in non-white women. (medscape.com)
  • We conclude that EBOV is shed in a wide variety of bodily fluids during the acute period of illness but that the risk of transmission from fomites in an isolation ward and from convalescent patients is low when currently recommended infection control guidelines for the viral hemorrhagic fevers are followed. (nih.gov)
  • they are now subject to compliance with the Sarbanes-Oxley Act, Section 404, which also is driving the need for vulnerability and risk assessments to be conducted for publicly traded companies. (informit.com)
  • During the meeting, Mary will review the risk and assist with the completion of the form. (ithaca.edu)
  • NEW YORK (GenomeWeb) - The European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) completed a review of Ariad Pharmaceuticals' Iclusig (ponatinib) and recommended that the company continue to sell the drug for the leukemia indications for which it is already approved. (genomeweb.com)
  • Complete the Event Risk Assessment form for events on campus at least 30 days before your event. (ithaca.edu)
  • The committee also noted that "the risk of vascular occlusive events is likely dose-related," and such risk information will need to be included in drug labeling. (genomeweb.com)
  • The results may show you have a low, moderate, or high risk of falling. (medlineplus.gov)
  • Organizations must now be information security conscious and must develop and implement proper security controls based on the results of their internal risk assessment and vulnerability assessment. (informit.com)