Surgery-related factors and local recurrence of Wilms tumor in National Wilms Tumor Study 4. (1/13426)

OBJECTIVE: To assess the prognostic factors for local recurrence in Wilms tumor. SUMMARY BACKGROUND DATA: Current therapy for Wilms tumor has evolved through four studies of the National Wilms Tumor Study Group. As adverse prognostic factors were identified, treatment of children with Wilms tumor has been tailored based on these factors. Two-year relapse-free survival of children in the fourth study (NWTS-4) exceeded 91%. Factors once of prognostic import for local recurrence may lose their significance as more effective therapeutic regimens are devised. METHODS: Children evaluated were drawn from the records of NWTS-4. A total of 2482 randomized or followed patients were identified. Local recurrence, defined as recurrence in the original tumor bed, retroperitoneum, or within the abdominal cavity or pelvis, occurred in 100 children. Using a nested case-control study design, 182 matched controls were selected. Factors were analyzed for their association with local failure. Relative risks and 95% confidence intervals were calculated, taking into account the matching. RESULTS: The largest relative risks for local recurrence were observed in patients with stage III disease, those with unfavorable histology (especially diffuse anaplasia), and those reported to have tumor spillage during surgery. Multiple regression analysis adjusting for the combined effects of histology, lymph node involvement, and age revealed that tumor spillage remained significant. The relative risk of local recurrence from spill was largest in children with stage II disease. The absence of lymph node biopsy was also associated with an increased relative risk of recurrence, which was largest in children with stage I disease. The survival of children after local recurrence is poor, with an average survival rate at 2 years after relapse of 43%. Survival was dependent on initial stage: those who received more therapy before relapse had a worse prognosis. CONCLUSIONS: This study has demonstrated that surgical rupture of the tumor must be prevented by the surgeon, because spills produce an increased risk of local relapse. Both local and diffuse spills produce this risk. Stage II children with local spill appear to require more aggressive therapy than that used in NWTS-4. The continued critical importance of lymph node sampling in conjunction with nephrectomy for Wilms tumor is also established. Absence of lymph node biopsy may result in understaging and inadequate treatment of the child and may produce an increased risk of local recurrence.  (+info)

Role of schools in the transmission of measles in rural Senegal: implications for measles control in developing countries. (2/13426)

Patterns of measles transmission at school and at home were studied in 1995 in a rural area of Senegal with a high level of vaccination coverage. Among 209 case children with a median age of 8 years, there were no deaths, although the case fatality ratio has previously been 6-7% in this area. Forty percent of the case children had been vaccinated against measles; the proportion of vaccinated children was higher among secondary cases (47%) than among index cases (33%) (prevalence ratio = 1.36, 95% confidence interval (CI) 1.04-1.76). Vaccinated index cases may have been less infectious than unvaccinated index cases, since they produced fewer clinical cases among exposed children (relative risk = 0.55, 95% CI 0.29-1.04). The secondary attack rate was lower in the schools than in the homes (relative risk = 0.31, 95% CI 0.20-0.49). The school outbreaks were protracted, with 4-5 generations of cases being seen in the two larger schools. Vaccine efficacy was found to be 57% (95% CI -23 to 85) in the schools and 74% (95% CI 62-82) in the residential compounds. Measles infection resulted in a mean of 3.8 days of absenteeism per case, though this did not appear to have an impact on the children's grades. Among the index cases, 56% of children were probably infected by neighbors in the community, and 7% were probably infected at health centers, 13% outside the community, and 24% in one of the three schools which had outbreaks during the epidemic. However, most of the school-related cases occurred at the beginning and therefore contributed to the general propagation of the epidemic. To prevent school outbreaks, it may be necessary to require vaccination prior to school entry and to revaccinate children in individual schools upon detection of cases of measles. Multidose measles vaccination schedules will be necessary to control measles in developing countries.  (+info)

Asthma visits to emergency rooms and soybean unloading in the harbors of Valencia and A Coruna, Spain. (3/13426)

Soybean unloading in the harbor of Barcelona, Spain, has been associated with large increases in the numbers of asthma patients treated in emergency departments between 1981 and 1987. In this study, the association between asthma and soybean unloading in two other Spanish cities, Valencia and A Coruna, was assessed. Asthma admissions were retrospectively identified for the period 1993-1995, and harbor activities were investigated in each location. Two approaches were used to assess the association between asthma and soybean unloading: One used unusual asthma days (days with an unusually high number of emergency room asthma visits) as an effect measure, and the other estimated the relative increase in the daily number of emergency room visits by autoregressive Poisson regression, adjusted for meteorologic variables, seasonality, and influenza incidence. No association between unusual asthma days and soya unloading was observed in either Valencia or A Coruna, except for one particular dock in Valencia. When the association between unloaded products and the daily number of emergency asthma visits was studied, a statistically significant association was observed for unloading of soya husk (relative risk = 1.50, 95% confidence interval 1.16-1.94) and soybeans (relative risk = 1.31, 95% confidence interval 1.08-1.59) in A Coruna. In Valencia, a statistical association was found only for the unloading of soybeans at two particular docks. Although these findings support the notion that asthma outbreaks are not a common hidden condition in most harbors where soybeans are unloaded, the weak associations reported are likely to be causal. Therefore, appropriate control measures should be implemented to avoid soybean dust emissions, particularly in harbors with populations living in the vicinity.  (+info)

Maternal second trimester serum tumor necrosis factor-alpha-soluble receptor p55 (sTNFp55) and subsequent risk of preeclampsia. (4/13426)

Preeclampsia is characterized by diffuse vascular endothelial dysfunction. Tumor necrosis factor-alpha (TNF-alpha), which plays a key role in the cytokine network responsible for immunoregulation, is also known to contribute to endothelial dysfunction and other metabolic disturbances noted in preeclampsia. Results from cross-sectional studies and one longitudinal study indicate that TNF-alpha (or its soluble receptor, sTNFp55) is increased in the peripheral circulation and amniotic fluid of women with preeclampsia as compared with normotensive women. Between December 1993 and August 1994, prediagnostic sTNFp55 concentrations (a marker of excessive TNF-alpha release) were measured in 35 women with preeclampsia and 222 normotensive women to determine whether elevations precede the clinical manifestation of the disorder. Logistic regression procedures were used to calculate maximum likelihood estimates of odds ratios and 95% confidence intervals. Mean second trimester (15-22 weeks' gestation) serum sTNFp55 concentrations, measured by enzyme-linked immunosorbent assay, were 14.4% higher in preeclamptic women than in normotensive controls (716.6 pg/ml (standard deviation 193.6) vs. 626.4 pg/ml (standard deviation 158.0); p = 0.003). The relative risk of preeclampsia increased across successively higher quintiles of sTNFp55 (odds ratios were 1.0, 1.3, 2.1, and 3.7, with the lowest quintile used as the referent; p for trend = 0.007). After adjustment for maternal age, adiposity, and parity, the relative risk between extreme quintiles was 3.3 (95% confidence interval 0.8-13.4). These findings indicate that the level of TNF-alpha in maternal circulation is increased prior to the clinical manifestation of the disorder, and they are consistent with the hypothesized role of cytokines in mediating endothelial dysfunction and the pathogenesis of preeclampsia. Further work is needed to identify modifiable risk factors for the excessive synthesis and release of TNF-alpha in pregnancy, and to assess whether lowering of TNF-alpha concentrations in pregnancy alters the incidence and severity of preeclampsia.  (+info)

Relation between obesity and breast cancer in young women. (5/13426)

This study was conducted to assess the relation between body size and risk of breast cancer among young women. A case-control study was conducted among women aged 21-45 years living in three counties in Washington State. Cases were women born after 1944 with invasive or in situ breast cancer that was diagnosed between January 1, 1983, and April 30, 1990. Controls were selected using random digit dialing and were frequency-matched to cases on the basis of age and county of residence. Interviews took place between 1986 and 1992. Body size was evaluated using indices from several different time periods. After adjustment for confounders, a decreased risk of breast cancer was found for women in the highest quintile of body mass index (weight (kg)/height (m)2) as compared with the lowest quintile (for maximum lifetime body mass index, odds ratio = 0.69, 95% confidence interval (CI) 0.51-0.94). Age modified the relation between body size and risk of breast cancer. The odds ratio for women in the highest quintile of maximum body mass index who were aged 21-35 years was 0.29 (95% CI 0.16-0.55), as compared with an odds ratio of 1.5 for women aged 36-45 years (95% CI 0.9-2.5) (p for interaction = 0.003). This study supports prior research showing a decreased risk of breast cancer associated with increased body size among premenopausal or young women. More detailed analysis in this study found a strong effect that was limited to the youngest age group (< or = 35 years).  (+info)

Why do short term workers have high mortality? (6/13426)

Increased mortality is often reported among workers in short term employment. This may indicate either a health-related selection process or the presence of different lifestyle or social conditions among short term workers. The authors studied these two aspects of short term employment among 16,404 Danish workers in the reinforced plastics industry who were hired between 1978 and 1985 and were followed to the end of 1988. Preemployment hospitalization histories for 1977-1984 were ascertained and were related to length of employment between 1978 and 1988. Workers who had been hospitalized prior to employment showed a 20% higher risk of early termination of employment than those never hospitalized (rate ratio (RR) = 1.20, 95% confidence interval (CI) 1.16-1.29), and the risk increased with number of hospitalizations. For workers with two or more preemployment hospitalizations related to alcohol abuse or violence, the rate ratios for short term employment were 2.30 (95% CI 1.74-3.06) and 1.86 (95% CI 1.35-2.56), respectively. An unhealthy lifestyle may also be a determinant of short term employment. While it is possible in principle to adjust for lifestyle factors if proper data are collected, the health-related selection of workers requires careful consideration when choosing a reference group for comparative studies of cumulative occupational exposure.  (+info)

Epidemiology of drug-resistant tuberculosis in Texas. (7/13426)

During 1987-1996, over 22,000 tuberculosis cases were reported in Texas, at an average annual incidence rate of 12.5 cases per 100,000 population. Counties with the highest rates were located along the Mexico-Texas border and in northwestern Texas. Nine percent of cases were resistant to at least one of the five first-line antituberculosis drugs used for treatment. Almost 5 percent (4.6%) were resistant to isoniazid, either alone or in combination with other antibiotics; 2.3% were resistant to rifampin; and only 1.3% were resistant to both isoniazid and rifampin. Being a recurrent case, being foreign-born, being 20-39 years of age, and residing in a Mexico-Texas border county were independent risk factors for isoniazid resistance and rifampin resistance. Tuberculosis patients with human immunodeficiency virus (HIV) infection were more likely to have rifampin resistance and less likely to have isoniazid resistance than patients without HIV infection. Factors associated with multi-drug-resistant tuberculosis included a history of previous tuberculosis (relative risk (RR) = 4.91, 95% confidence interval (CI) 3.5-6.8), non-US birth (RR = 2.69, 95% CI 2.1-3.5), age younger than 20 years (RR = 1.97, 95% CI 1.1-3.5), age 20-39 years (RR = 1.82, 95% CI 1.3-2.6), and residence in a Mexico-Texas border county (RR = 2.33, 95% CI 1.8-3.1).  (+info)

Outcome of pregnancy in women with congenital shunt lesions. (8/13426)

OBJECTIVE: To evaluate the outcome of pregnancy in women with congenital shunt lesions. SETTING: Retrospective study in a tertiary care centre. METHODS: Pregnancy history was obtained by a standardised questionnaire and medical records were reviewed. PATIENTS: 175 women were identified, at a mean (SD) age of 42 (14) years. Pregnancies occurred in 126 women: 50 with an atrial septal defect, 22 with a ventricular septal defect, 22 with an atrioventricular septal defect, 19 with tetralogy of Fallot, and 13 with other complex shunt lesions. RESULTS: 309 pregnancies were reported by 126 woman (2.5 (1.6) pregnancies per woman). The shortening fraction of the systemic ventricle was 40 (8)%, and 98% were in New York Heart Association class I-II at last follow up. Spontaneous abortions occurred in 17% of pregnancies (abortion rate, 0.4 (0.9) per woman). Gestational age of the 241 newborn infants was 8.8 (0.8) months. There were no maternal deaths related to pregnancy. Pre-eclampsia and embolic events were observed in 1.3% and 0.6%, respectively of all pregnancies. Women with complex shunt lesions more often underwent caesarean section (70% v 15-30%, p = 0.005) and gave birth to smaller babies for equivalent gestation (2577 (671) g v 3016 (572) to 3207 (610) g, p < 0.05). The recurrence risk of congenital heart disease was 2.5%. CONCLUSIONS: The outcome of pregnancy is favourable in women with congenital shunt lesions if their functional class and their systolic ventricular function are good. Such patients can be reassured.  (+info)

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... may refer to: At Risk (1994 film), an American romantic drama film At Risk (2010 film), an American TV movie At Risk ( ... book), a 1988 book by Alice Hoffman This disambiguation page lists articles associated with the title At Risk. If an internal ...
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A risk-reversal is an option position that consists of selling (that is, being short) an out of the money put and buying (i.e. ... Risk reversal can refer to the manner in which similar out-of-the-money call and put options, usually foreign exchange options ... In finance, risk reversal (also known as a conversion when an investment strategy) can refer to a measure of the volatility ... A risk reversal position can simulate the profit and loss behavior of owning an underlying security; therefore it is sometimes ...
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Such variability in rainfall means there are many and varied associated risks (as well as opportunities). These risks can range ... Bureau Home , Water and the Land , Weather and Climate Risk These pages require JavaScript. Please turn it on in your browser. ... Risks. Possible short-term flooding. Opportunities. Good opportunities for rainfall through the centre of the continent, as ... Risks. MJO, while occasionally producing very good rains, is somewhat erratic in the rain that occurs over the continent.. ...
Explore the latest news and expert commentary on Risk Management, brought to you by the editors of InformationWeek ... Dialing Down AI Risks While Getting Smarter About Its UsesDialing Down AI Risks While Getting Smarter About Its Uses. bySamuel ... 2023 Cyber Risk and Resiliency Report: How CIOs Are Dueling Disaster in 20232023 Cyber Risk and Resiliency Report: How CIOs Are ... 2023 Cyber Risk and Resiliency Report: How CIOs Are Dueling Disaster in 2023Cyber Risk and Resiliency Report: How CIOs Are ...
... places and things that we care about at risk. Coastal communities face a range of unique flooding hazards including storm surge ... Risk MAP * Products and Tools * Guidance & Reports * Cooperating Technical Partners * Know Your Risk * Homeowners, Renters or ... Risk Management * Hazard Mitigation Planning * Climate Resilience * Building Science * Earthquake Risk * Dam Safety * Hurricane ... Through Risk Mapping, Assessment and Planning (Risk MAP) , FEMA is updating the nations coastal Flood Insurance Studies (FIS) ...
Deloittes Cyber Risk services address complex cyber risk management challenges, enabling clients to perform better and build ... Developing a cyber risk programme in line with your organisations strategic objectives and risk appetite.. ... The ability to innovate, to use new technologies and to grow securely requires an end-to-end cyber risk strategy driven by an ... We design the processes and services to help you assess and monitor risks that could cause crises, prevent, and avoid possible ...
... who says that top executives and boards of directors are looking for risk management guidance, and if risk experts in their ... Changing the risk management culture of any organization will be tough… do what you can to lead some of these important changes ... And just last week, my colleague Craig Symons published a report explaining key issues in risk management for the CIO. ... Ive written here several times in the past discussing the changing role and the increasing value of risk management ...
Appreciate how to use FMEA, risk ranking, cause effect matrix and other related Risk Analysis techniques, such as process flow ... Understand how to set up and run a risk management exercise, including team selection, risk assessment, analysis, control, ... Pharmceutical Quality Risk Management Training 16 January 2017 09:00-17:00, Reading, United Kingdom ... The course will be aligned to the latest science and risk based principles and regulatory guidances in the EU and US. ...
Find out about STI risks of various sexual activities, including oral and anal sex, and fingering. ... The risk of passing on or getting HIV during oral sex is lower than anal or vaginal sex without a condom. However, the risk is ... Theres a risk of getting or passing on STIs if youre giving or receiving oral sex. The risk increases if either of you has ... In nearly every case, condoms will help protect you against this risk. Learn about the risks associated with various sexual ...
The process for finding trustworthy men and women is intense - but imperfect.
... places and things that we care about at risk. Coastal communities face a range of unique flooding hazards including storm surge ... Risk MAP * Products and Tools * Guidance & Reports * Cooperating Technical Partners * Know Your Risk * Homeowners, Renters or ... Risk Management * Hazard Mitigation Planning * Climate Resilience * Building Science * Earthquake Risk * Dam Safety * Hurricane ... Through Risk Mapping, Assessment and Planning (Risk MAP) , FEMA is updating the nations coastal Flood Insurance Studies (FIS) ...
Links to a range of documents related to communication and risk communication. ... CDCs Crisis and Emergency Risk Communication Online Course. This online Crisis and Emergency Risk Communication course will ... A Primer on Health Risk Communication. The purpose of this Primer is to provide a framework of principles and approaches for ... Environmental Health Resources Self Learning Module: Risk Communication pdf icon[4.55 MB]. ATSDR developed this module to ...
I am going to talk about measuring systemic risk, based on my joint paper, ... "Risk Topography: Systemic Risk and Macro Modeling," NBER Books, National Bureau of Economic Research, Inc, number brun11-1, May ... "Testing Macroprudential Stress Tests: The Risk of Regulatory Risk Weights," CEPR Discussion Papers 9431, C.E.P.R. Discussion ... "Testing Macroprudential Stress Tests: The Risk of Regulatory Risk Weights," CEPR Discussion Papers 9800, C.E.P.R. Discussion ...
Risk management remains an important tool for classifying and assessing current risks and threats. ... How to achieve the Interoperability of EU Risk Management Frameworks The European Union Agency for Cybersecurity (ENISA) issues ... an analysis of the interoperability potential of cybersecurity risk management frameworks and methodologies to improve decision ...
Leadership in organizing Risk & Resilience. Whether you are a seasoned professional, a dedicated academic or an ambitious ... student with a passion for risk management, resilience of safety, this festiva… ... Leadership in organising Risk & Resilience. On November 7, 2024, the 8th edition of our festival comes to life, and this time ... This is the opportunity to immerse yourself in the world of Risk & Resilience and discover how leadership plays a critical role ...
... credit risk, operational risk, interest rate risk, mortality risk, longevity risks, etc. The term "risk" has a long history in ... It includes market risk, credit risk, liquidity risk and operational risk. In finance, risk is the possibility that the actual ... Where risk criteria refer to the individual risk, the risk assessment must use this metric. Group (or societal risk) - the ... Risk evaluation involves comparing estimated levels of risk against risk criteria to determine the significance of the risk and ...
  • Resilience is about addressing the root causes of crises while strengthening the capacities and resources of a system in order to cope with risks, stresses and shocks. (oecd.org)
  • The Resilience Systems Analysis (RSA) is designed to help DAC members and their partners effectively integrate risk and resilience into their strategies and programme planning. (oecd.org)
  • Risk is one of nine focus areas in our framework for building enterprise resilience. (ey.com)
  • Click here to learn how coastal communities are reducing risk and building resilience using FEMA data. (fema.gov)
  • Whether you are a seasoned professional, a dedicated academic or an ambitious student with a passion for risk management, resilience of safety, this festival offers a unique opportunity to deepen your knowledge and network with like-minded people. (utwente.nl)
  • This is the opportunity to immerse yourself in the world of Risk & Resilience and discover how leadership plays a critical role in organising risk and strengthening resilience. (utwente.nl)
  • Enable conversations with IT, security, and the line-of-business to improve processes and mitigate risks. (ibm.com)
  • These local professionals may also be aware of efforts already taken to mitigate the risks. (realtor.com)
  • Access the Security Risks page to analyze and mitigate the discovered misconfigurations, application vulnerabilities, and user behavior risks. (bitdefender.com)
  • Successful organizations know that risk can come from every angle - upside, downside and outside - and can be hard to see, anticipate and respond to. (ey.com)
  • The interplay between upside and downside risk is important to understand the long-term decisions being made to prevent risk and how that impacts an organization's ability to meet its future business strategy and objectives. (ey.com)
  • Therefore, organizations should broaden their focus on the risk landscape and consider three categories of risks: upside, outside and downside. (ey.com)
  • Measuring Systemic Risk ," CEPR Discussion Papers 8824, C.E.P.R. Discussion Papers. (repec.org)
  • A Theory of Systemic Risk and Design of Prudential Bank Regulation ," CEPR Discussion Papers 7164, C.E.P.R. Discussion Papers. (repec.org)
  • Properties of Foreign Exchange Risk Premiums ," CEPR Discussion Papers 8503, C.E.P.R. Discussion Papers. (repec.org)
  • Heart disease risk factors and diagnoses are more common among ethnic minorities. (clevelandclinic.org)
  • When it comes to heart disease risk factors, minority groups also carry a heavier burden. (clevelandclinic.org)
  • These are two major risk factors for heart disease. (clevelandclinic.org)
  • Comprehensive analysis, disclosure and management of fiscal risks - factors that can cause fiscal outcomes to differ from expectations - is needed to ensure sound public finances and macroeconomic stability as well as fiscal transparency. (imf.org)
  • Environmental risk factors are those that are attributable to the layout, design, and amenities of the physical workspace. (cdc.gov)
  • Risk factors are things that increase your chance of getting a disease or condition. (medlineplus.gov)
  • This article discusses the risk factors for stroke and things you can do to lessen your risk. (medlineplus.gov)
  • Some risk factors for stroke you cannot change. (medlineplus.gov)
  • Changing the risk factors that you have control over will help you live a longer, healthier life. (medlineplus.gov)
  • It will help control some of your risk factors. (medlineplus.gov)
  • I think before we conclude that we should be giving our patients pomegranate juice, we need to do bigger studies in other settings [with] more diverse populations and, of course, look beyond just the risk factors that they measured. (medscape.com)
  • Cite this: Pomegranate Juice Lowers Cardiovascular Risk Factors - Medscape - Nov 12, 2011. (medscape.com)
  • The triangles show the relative importance of different risk factors for child maltreatment. (who.int)
  • Not all risk factors are found in all social and cultural contexts. (who.int)
  • Analyses were stratified by susceptibility to ASCVD based on family history, genetic risk, and established risk factors. (medscape.com)
  • Lifestyle related risk factors such as tobacco use, harmful use of alcohol, unhealthy diet, and insufficient physical activity are known modifiable contributors to non-communicable diseases (NCDs) and mental health issues2. (who.int)
  • Preventing these risk factors will have a dual beneficial effect of reducing the number of people at risk of severe disease as well as improving the recovery of those affected by COVID-19. (who.int)
  • See Risk Factors . (medscape.com)
  • EGOS 2017 , Copenhagen, "Sub-theme 16: Risk, Value and Virtue in the Audit Society", organized by Mike Power, Steve Maguire and Roger Friedland. (lse.ac.uk)
  • The ISRM program is based on risk assessment and developed in consideration of University priorities, staffing, and budget. (fordham.edu)
  • Risk Assessment is the process of taking identified risks and analyzing their potential severity of impact and likelihood of occurrence. (fordham.edu)
  • Through Risk Mapping, Assessment and Planning (Risk MAP) , FEMA is updating the nation's coastal Flood Insurance Studies (FIS) and Flood Insurance Rate Maps (FIRMs, or flood maps), where appropriate, and publishing new flood maps of densely populated areas that were not previously mapped. (fema.gov)
  • After the New gTLD program is launched, staff to provide periodic status reports to the BRC regarding the assessment of actual performance measured against the assessed risks. (icann.org)
  • Risk assessment, or risk management, today is all too often purely a "checklist function. (bcg.com)
  • Risk advantage means that companies integrate risk assessment and mitigation into their strategic decision making. (bcg.com)
  • It facilitates a collective and contextualised understanding of the impacts of risks and stressors on a system's main assets. (oecd.org)
  • The tools provide a practical basis to help countries identify, analyze, manage and disclose fiscal risks. (imf.org)
  • IBM Security® Guardium® Data Risk Manager provides you and your teams with a business-consumable data risk control center that helps to uncover, analyze, and visualize data-related business risks so they can take action to protect your business. (ibm.com)
  • Analyze identified risks, their type, impacted information assets, and additional elements to deliver a comprehensive view of their potential probability and business impact. (ibm.com)
  • With its business-consumable dashboard, this helps privacy and data officers across IBM uncover, analyze, and visualize business risks around sensitive data so they can take corrective action. (ibm.com)
  • Examples of relevant Flood Risk Products for coastal areas include coastal depth grids (which show how deep the water would be during the 1%-annual-chance flood at any given location) and tools that show where the risks from wave heights, severity of flooding, and erosion may have increased. (fema.gov)
  • The First Street Foundation's Flood Factor ™ uses a risk score ranging from 1 to 10 and represents both a property's risk of flooding and severity of flooding over the course of a 30-year period. (realtor.com)
  • Alcohol impairs thoughts, judgement, decision-making and behaviour and increases the risk, frequency and severity of interpersonal violence. (who.int)
  • Download our 2024 Planning Guide for Security and Risk Leaders to see where strategic cybersecurity investments (and divestments) can deliver more business value. (forrester.com)
  • The European Union Agency for Cybersecurity (ENISA) issues an analysis of the interoperability potential of cybersecurity risk management frameworks and methodologies to improve decision-making. (europa.eu)
  • Many companies do a good job of analyzing and planning for competitive risks, such as new market entrants or the threat of substitution, but they give only pro forma attention to noncompetitive uncertainties, including cybersecurity, natural disasters, and geopolitical risk-even though the impact of these events can be immediate and catastrophic. (bcg.com)
  • How do cardiovascular disease risks vary by race and ethnicity? (clevelandclinic.org)
  • This condition raises a person's risk for cardiovascular disease down the road. (clevelandclinic.org)
  • Dr. Kristal speculated that the consumption of pomegranate juice might lower the risk for cardiovascular disease in patients on hemodialysis, and recommended that it be added to diets that improve cardiometabolic risks, including low-salt diets, Dietary Approaches to Stop Hypertension (DASH), and the Mediterranean diet. (medscape.com)
  • Climbing more than five flights of stairs daily is associated with a reduced risk of atherosclerotic cardiovascular disease (ASCVD) of about 20%, new observational data suggest. (medscape.com)
  • It is a major risk factor for non-communicable diseases (NCDs) including cardiovascular disease, chronic respiratory disease, diabetes and cancer4. (who.int)
  • Combining our risk consultancy with the latest technologies and tailored strategies in cyber, sustainability, strategy, regulation, compliance, and controls, we can provide valuable insights that help keep your business resilient through crises and complex times. (deloitte.com)
  • The purpose of this policy is to facilitate compliance with applicable federal and state laws and regulations, protect the confidentiality and integrity of the University's IT Resources, and enable informed decisions regarding Risk Management. (fordham.edu)
  • We'll implement a variety of solutions in a programmatic fashion, for instance, implementing an integrated governance, risk management, and compliance (GRC) platform or spot fixes in areas such as developing and validating risk models, optimizing controls, implementing programs for managing compliances, contracts and program-related risks. (ey.com)
  • Only SAS delivers comprehensive risk solutions that include AI and best practices to help you align strategies and goals across finance, risk, actuarial and regulatory compliance functions. (sas.com)
  • Find or establish internal committees where you can offer your risk management expertise and exert more influence among compliance, legal, finance, lines of business, or other stakeholders. (forrester.com)
  • The emphasis is on detailed risk registers, compliance questionnaires, and process. (bcg.com)
  • Our ever-changing world creates risk and uncertainty, but it also offers opportunity. (deloitte.com)
  • Risk involves uncertainty about the effects/implications of an activity with respect to something that humans value (such as health, well-being, wealth, property or the environment), often focusing on negative, undesirable consequences. (wikipedia.org)
  • ISO Guide 73:2009 defines risk as: effect of uncertainty on objectives Note 1: An effect is a deviation from the expected - positive or negative. (wikipedia.org)
  • This links "risk" to "uncertainty", which is a broader term than chance or probability. (wikipedia.org)
  • This definition comes from Knight's "Risk, Uncertainty and Profit" (1921). (wikipedia.org)
  • Do we as investors, customers, or business partners have similar expectations with respect to companies' ability and preparedness to manage risk and uncertainty? (bcg.com)
  • The opportunity is for companies that do make the necessary assessments and have the plans in place to deal with risk-and with uncertainty in general. (bcg.com)
  • Risk advantage marries these two ideas: it is the ability to systematically manage the uncertainty (or uncertainties) inherent in any given strategic position in order to generate an attractive return with less risk taken. (bcg.com)
  • SAS enables you to put on-demand, high-performance insurance risk analytics in the hands of your CRO and risk professionals. (sas.com)
  • Update legacy processes with a modernized risk and finance infrastructure that supports scalable, high-quality data, workflow, analytics and reporting. (sas.com)
  • Endpoint Risk Analytics ( ERA ) identifies, assesses, and remediates Windows endpoints weaknesses via security risk scans (on-demand or scheduled via policy), taking into account a vast number of indicators of risk. (bitdefender.com)
  • Global insurer moves from transactional to strategic by teaming with Deloitte for cyber solutions and Operate services​, reducing complexity, costs, and risks with an IAM transformation​. (deloitte.com)
  • Information Security Risk Management (ISRM) is a program that consistently identifies and tracks information security risks, implements plans for remediation, and guides strategic resource planning. (fordham.edu)
  • Learn how best-in-class risk management will create value through driving confidence in achieving strategic objectives and maintaining stakeholder trust. (ey.com)
  • We help boards and CxOs build agile and risk-aware organizations that make better decisions to achieve their strategic objectives. (ey.com)
  • Organizations grow and generate value through a series of strategic business decisions - decisions that require taking risks. (ey.com)
  • FEMA is working with local community officials to produce additional data and hazard mitigation tools that will enable more strategic emergency preparedness, planning and risk reduction in coastal communities. (fema.gov)
  • Deloitte's Cyber services balance the requirements to be secure, vigilant and resilient with strategic objectives and the risk appetite of the organisation. (deloitte.com)
  • Developing a cyber risk programme in line with your organisation's strategic objectives and risk appetite. (deloitte.com)
  • A person's risk of severe illness from COVID-19 increases as the number of underlying medical conditions they have increases. (cdc.gov)
  • The risk increases if either of you has sores or cuts around the mouth, genitals or anus. (www.nhs.uk)
  • If there are any cuts or sores on the fingers, no matter how small, the risk of passing on or getting an STI increases. (www.nhs.uk)
  • A risk factor is something that increases your chance of getting a disease or health problem. (medlineplus.gov)
  • Our findings suggest that dairy intake increases Parkinson's disease risk," the investigators concluded. (medscape.com)
  • Heavy use of alcohol increases the risk of acute respiratory distress syndrome (ARDS), one of the most severe complications of COVID-196. (who.int)
  • EGOS 2015 , Athens, "Sub-theme 47: Risk and Organizations: Understanding Reason, Reflexivity and Responsibility in Risk Management", organized by Robert P. Gephart Jr, Steve Maguire and Mike Power. (lse.ac.uk)
  • Historically, organizations have focused on risks that can be managed through the implementation of controls. (ey.com)
  • Typically, organizations have several functions that are tasked with different aspects of risk management. (ey.com)
  • The article quotes the Institute of Risk Management's deputy chairman, Alex Hindson, who says that top executives and boards of directors are looking for risk management guidance, and if risk experts in their organizations can't step up to fill that role in their 'window of opportunity,' it will be filled instead by auditors, finance professionals, or external consultants. (forrester.com)
  • The international standard for risk management, ISO 31000, provides principles and general guidelines on managing risks faced by organizations. (wikipedia.org)
  • The Centers for Medicare & Medicaid Services (CMS) is in the process of drafting comprehensive ligature risk interpretive guidance to provide direction and clarity for Regional offices (RO), State Survey Agencies (SAs), and accrediting organizations (AOs). (cms.gov)
  • They originate as systemic risk events before becoming your current nightmare scenario. (forrester.com)
  • I am going to talk about measuring systemic risk, based on my joint paper, "Measuring Systemic Risk," with Lasse Pederson, Thomas Philippon, and Matt Richardson, who are all my colleagues at NYU Stern.The way bank regulations have been thought and implemented so far has invariably focused only on the risk of individual banks. (repec.org)
  • Measuring Systemic Risk ," World Scientific Book Chapters , in: Stijn Claessens & Douglas D Evanoff & George G Kaufman & Laura E Kodres (ed. (repec.org)
  • Measuring Systemic Risk ," Review of Financial Studies , Society for Financial Studies, vol. 30(1), pages 2-47. (repec.org)
  • Measuring Systemic Risk ," World Scientific Book Chapters , in: Oliviero Roggi & Edward I Altman (ed. (repec.org)
  • Measuring systemic risk ," Working Papers (Old Series) 1002, Federal Reserve Bank of Cleveland. (repec.org)
  • Measuring systemic risk ," Proceedings 1140, Federal Reserve Bank of Chicago. (repec.org)
  • A theory of systemic risk and design of prudential bank regulation ," Journal of Financial Stability , Elsevier, vol. 5(3), pages 224-255, September. (repec.org)
  • ORG workshop "(Re)constructing risks for decision making", 4th and 5th July 2022, Copenhagen Business School (Denmark) and online. (lse.ac.uk)
  • If you or your family member are at high risk for severe illness, wear a mask or respirator with greater protection in public indoor spaces if you are in an area with a high COVID-19 hospital admission level . (cdc.gov)
  • Healthcare professionals should see Underlying Medical Conditions Associated with Higher Risk for Severe COVID-19 for more detailed information. (cdc.gov)
  • The list below does not include all possible conditions that put you at higher risk of severe illness from COVID-19. (cdc.gov)
  • The Equal Employment Opportunity Commission (EEOC) has updated its guidance on COVID-19 and the Americans with Disabilities Act (ADA), clarifying how to accommodate individuals who are at high risk for severe illness from the coronavirus. (shrm.org)
  • There are many conditions, physical and mental, that could put someone at higher risk of severe illness, said David Fram, director of ADA services with the National Employment Law Institute, headquartered in Golden, Colo. (shrm.org)
  • The IMF's Fiscal Risk Toolkit, guidance materials and capacity development help policymakers to identify, monitor, and manage fiscal risks. (imf.org)
  • The IMF has prepared a wide range of guidance notes to help countries better understand and manage fiscal risks. (imf.org)
  • These include high-level analytical and policy papers, detailed How to Notes that provide guidance on approaches to analyzing and managing specific fiscal risks, and individual country capacity development reports which aim to help countries strengthen monitoring, analysis, management and reporting of fiscal risks that is tailored to their particular situation. (imf.org)
  • To learn more about a property's flood history and potential flood risks, contact your real estate agent or local floodplain official for guidance. (realtor.com)
  • The Office of Risk Management has issued guidance to supplement any post-pandemic guidelines to alternate workforce strategies deployed in schools and units, with focus on remote work. (northwestern.edu)
  • Interim Guidance: Until CMS' comprehensive ligature risk interpretive guidance is released, the ROs, SAs and AOs may use their judgment as to the identification of ligature and other safety risk deficiencies, the level of citation for those deficiencies, as well as the approval of the facility's corrective action and mitigation plans to minimize risk to patient safety and remedy the identified deficiencies. (cms.gov)
  • The EEOC defines direct threat in its guidance on pandemics and the ADA as 'a significant risk of substantial harm to the health or safety of the individual or others that cannot be eliminated or reduced by reasonable accommodation. (shrm.org)
  • BRC chair to contact staff coordinating reviews related to the Affirmation of Commitments to provide further guidance on the types of risk identification that will be helpful to the BRC. (icann.org)
  • Their research covers a variety of topics including riskwork and risk management practices, crisis management and business continuity, internal controls and auditing, decision-making and risk regulation. (lse.ac.uk)
  • This online Crisis and Emergency Risk Communication course will stress the fundamentals of CDC's Crisis & Emergency Risk Communication (CERC). (cdc.gov)
  • The course has been designed to serve those who will perform crisis and risk communication and media relations in the event of a public health emergency. (cdc.gov)
  • Managing and Measuring Risk Emerging Global Standards and Regulations After the Financial Crisis , chapter 3, pages 65-98, World Scientific Publishing Co. Pte. (repec.org)
  • Crisis and Emergency Risk Communication (CERC) training can help responders and public health professionals prepare to communicate in an emergency. (cdc.gov)
  • CERC trainings are based on lessons learned during public health emergencies, evidence-based practices from the fields of risk and crisis communication, and psychology. (cdc.gov)
  • Through sample scenarios, you will have the opportunity to identify information needs and develop useful messages to help you communicate effectively and promote behaviors that reduce health risks during a global crisis or emergency. (cdc.gov)
  • IBM Security Guardium Data Risk Manager software is a unified dashboard for IBM Guardium , Symantec DLP, and IBM Information Governance Catalog that provides workflows for the discovery, classification and reporting of sensitive data and associated risks across the enterprise. (ibm.com)
  • Programmatically discover, classify, and report sensitive data and associated risks across the enterprise by integrating outputs from IBM Guardium, Symantec DLP, and IBM Information Governance Catalog. (ibm.com)
  • By delivering identity governance and administration, access management and privileged access management as a complete package, this turnkey solution helps you reduce implementation risk, improve cost efficiencies and dramatically accelerate your digital identity maturity. (deloitte.com)
  • Deloitte's Cyber Risk services address complex cyber risk management challenges, enabling clients to perform better and build more confident futures. (deloitte.com)
  • The ability to innovate, to use new technologies and to grow securely requires an end-to-end cyber risk strategy driven by an organisation's executive leadership. (deloitte.com)
  • Provide early visibility into potential risks that may impact sensitive business information assets, data, and processes. (ibm.com)
  • Providing multiple ratings on the listing details page paints a clearer picture of potential risks. (realtor.com)
  • Staff provided updated report on project-level risk management within the New gTLD program and risks identified within the program, with mitigation efforts also identified. (icann.org)
  • As issues of risk cut across traditional disciplinary boundaries, the group is open to the use of multiple perspectives and research methods to better understand the complex relationship between risk and organizing, including organization theory, strategy, and accounting as well as social studies of finance or of science and technology. (lse.ac.uk)
  • ORG holds a bi-annual sub-theme on risk at EGOS (European Group of Organization Studies) and organizes special research events. (lse.ac.uk)
  • Organizing risk: Organization and management theory for the risk society. (lse.ac.uk)
  • Identifying, managing and responding to these risks well position an organization to grow and remain successful. (ey.com)
  • Depending on the risk maturity of the organization, our Risk Transformation Consulting Services team will prioritize and implement digitization opportunities across the landscape of risk types and risk activities. (ey.com)
  • Changing the risk management culture of any organization will be tough… do what you can to lead some of these important changes. (forrester.com)
  • The First Street Foundation is a nonprofit organization that created Flood Factor ™ in an effort to provide accurate, publicly available flood risk assessments for individual properties. (realtor.com)
  • The International Organization for Standardization (ISO) Guide 73 provides basic vocabulary to develop common understanding on risk management concepts and terms across different applications. (wikipedia.org)
  • Staff confirmed work on each action item, including work on formation of the Risk Oversight Management Team and completion of the Enterprise Risk Management Guidelines, as well as coordination of outreach to the Numbers Resource Organization on IPv4 depletion issues, continuing work on risk areas related to the Affirmation of Commitments. (icann.org)
  • Birth control pills (particularly those with higher estrogen content) can raise your risk of blood clots. (medlineplus.gov)
  • Flood Factor ™ also depicts the likelihood of flood risk by depth of water. (realtor.com)
  • Note 4: Risk is often expressed in terms of a combination of the consequences of an event (including changes in circumstances) and the associated likelihood of occurrence. (wikipedia.org)
  • To avoid or overcome this organizational hazard, you must build synergy, develop agility in risk functions and processes and define and assign clear ownerships and accountabilities. (ey.com)
  • To help coastal communities understand and reduce their risks, FEMA has initiated coastal flood hazard studies for 100% of the populated coastline. (fema.gov)
  • The Federal Emergency Management Agency (FEMA) uses the latest science and technology to identify flood risk by mapping hazard zones across the U.S. These maps are defined by law to represent an area's flood risk at the time that it is documented and are used to determine flood insurance rates and help communities make decisions on how to manage land within these zones. (realtor.com)
  • The earliest use of the word "risk" was as a synonym for the much older word "hazard", meaning a potential source of harm. (wikipedia.org)
  • Better understanding of fiscal risks, combined with their transparent reporting and effective risk management underpin fiscal credibility and the sustainability of public finances. (imf.org)
  • Now you can identify and help prevent risks to sensitive business data that may impact business processes, operations, and competitive position. (ibm.com)
  • Examine current inventory and map business processes that involve high-risk data elements throughout the data lifecycle. (pwc.com)
  • Strategy, enterprise risk management (ERM), and business continuity processes operate in their own silos. (bcg.com)
  • Deviations from policies, procedures, or guidelines published and approved by Information Security and Assurance (ISA) may only be done cooperatively between ISA and the requesting entity with sufficient time to allow for appropriate risk analysis, documentation, and possible presentation to authorized University representatives. (fordham.edu)
  • ISO 31000:2018 "Risk management - Guidelines" uses the same definition with a simpler set of notes. (wikipedia.org)
  • You will be able to resolve certain security risks automatically from GravityZone Control Center , and view recommendations for mitigating endpoint vulnerabilities. (bitdefender.com)
  • The global COVID-19 pandemic is contributing to social and economic disruptions that may drive people to engage in risk-taking behavior and unhealthy habits. (who.int)
  • Anal sex has a higher risk of spreading STIs than many other types of sexual activity. (www.nhs.uk)
  • Men have a higher risk of getting heart disease and stroke than women, except in older adults. (medlineplus.gov)
  • If your parents had a stroke, you are at higher risk. (medlineplus.gov)
  • Among more than 156,000 hospitalized patients with ARDS, 16.8% of whom also had a diagnosis of PH, the presence of PH was associated with about a 50% higher risk for in-hospital mortality and a 37% higher risk for longer hospital stays. (medscape.com)
  • On the other hand, in the event that an employer is considering keeping an employee out of the workplace because the employee is part of the higher-risk group, the rules are far stricter,' Hartstein said. (shrm.org)
  • Risk A ssessments must identify, quantify, and prioritize risk acceptance and objectives relevant to the University. (fordham.edu)
  • We have created a programme that has synergies between disaster risk management and climate change adaptation because these two areas are strongly interlinked. (lu.se)
  • Magnus Hagelsteen, Programme Director, MSc in Disaster Risk Management and Climate Change Adaptation. (lu.se)
  • Managing risk isn't just about responding to change. (pwc.com)
  • When you are one of the largest beauty and consumer goods companies in the world - winning and delivering in markets while managing risks and being compliant with regulations is a constant challenge. (deloitte.com)
  • The results are to guide and determine the appropriate management action and priorities for managing information security risks and for implementing C ontrols to protect against these risks. (fordham.edu)
  • Implementing and managing solutions across the lines of defense owned by process owners, controlling functions, and auditors requires an integrated view of risk. (ey.com)
  • Managing risk, at all timescales, is one of the keys to a successful enterprise. (bom.gov.au)
  • Discover how leading risk management practices create value and a competitive advantage by embracing disruption with trust and confidence. (ey.com)
  • Read best practices and success stories about mitigating coastal risk. (fema.gov)
  • SAS helps RSA Canada accurately predict the impact of risk characteristics on customer premiums, while identifying customer segments with growth potential. (sas.com)
  • Properties of foreign exchange risk premiums ," Journal of Financial Economics , Elsevier, vol. 105(2), pages 279-310. (repec.org)
  • Properties of Foreign Exchange Risk Premiums ," Working Paper series 10_12, Rimini Centre for Economic Analysis. (repec.org)
  • These non-regulatory tools are called Flood Risk Products. (fema.gov)
  • To learn more about FEMA's Flood Risk Products click here . (fema.gov)
  • Understand your flood risk and view your flood maps . (fema.gov)
  • Sign up for emails to receive coastal flood risk and mapping updates. (fema.gov)
  • Navigating institutional complexity: The production of risk culture in the financial sector. (lse.ac.uk)
  • Its complexity reflects the difficulty of satisfying fields that use the term risk in different ways. (wikipedia.org)
  • Rising complexity exacerbates the types of risk that companies face, and volatility amplifies the potential impact. (bcg.com)
  • Airlines are highly sensitive to risks and their first cousin, uncertainties, which can be both competitive and noncompetitive in nature and include economic dips, fuel price swings, and terror incidents. (bcg.com)
  • What is new in the last roughly 150 years is the extent to which average people have gotten access to financial devices which, by sharing risks, have reduced the economic uncertainties in their lives. (bostonreview.net)
  • We spoke to four people about their thoughts when it comes to the health uncertainties involved while protesting and why, to them, it's a risk worth taking. (yahoo.com)
  • Countercyclical Currency Risk Premia ," NBER Working Papers 16427, National Bureau of Economic Research, Inc. (repec.org)
  • A Long-Run Risks Explanation of Predictability Puzzles in Bond and Currency Markets ," NBER Working Papers 18357, National Bureau of Economic Research, Inc. (repec.org)
  • The classic multiplayer roguelike, Risk of Rain, returns with an extra dimension and more challenging action. (gamespot.com)
  • Because Flood Factor ™ shows the risk of flooding from rain, rivers, tides, and storm surge, and forecasts how these risks will change over time because of the environment, a home's Flood Factor ™ often differs from its FEMA flood zone designations. (realtor.com)
  • The University uses formal Information Security Risk Management (ISRM) programs that identify risks and implement plans to address and manage them. (fordham.edu)
  • Correlate security metrics from point security solutions to provide an end-to-end view of your security posture, using the common language of risk to communicate with the C-suite and the risk office. (ibm.com)
  • We provide security and risk services to both audit and non-audit clients in 153 countries worldwide. (pwc.com)
  • Security Risk? (wbur.org)
  • Calculate a risk score that highlights the parts of the business that are at risk. (ibm.com)
  • Risk return is another well-established practice: investors regularly calculate the risk of a stock or a bond to assess the return they need in order to be adequately compensated for investing their funds. (bcg.com)
  • In this environment, when a single bad actor can undermine hundreds of companies and institutions in just a few hours, the ability to turn the tables on risk and establish a sustainable "risk advantage" will be as important for the companies of the future as creating a competitive advantage is today. (bcg.com)
  • After scanning your network for indicators of risk, you will gain and overview of your network risk status through the Risk Management dashboard, available from the main menu. (bitdefender.com)
  • Hispanic women are more than twice as likely as white women to have diabetes, which is a major risk factor for heart disease. (clevelandclinic.org)
  • Other groups also face disadvantages that affect their risks for heart disease. (clevelandclinic.org)
  • Successful completion of this one day course provides the delegate with understanding of the principles of Quality Risk Management (QRM) and its practical application. (rsc.org)
  • The course will be aligned to the latest science and risk based principles and regulatory guidances in the EU and US. (rsc.org)
  • The purpose of this Primer is to provide a framework of principles and approaches for the communications of health risk information to diverse audiences. (cdc.gov)
  • One safety concern is that pomegranate juice contains a high level of potassium, so potassium overload is a risk, especially in patients with chronic kidney disease and dietary potassium restrictions. (medscape.com)
  • Ligature Risks Compromise Psychiatric Patients' Right to Receive Care in a Safe Setting: The care and safety of psychiatric patients and the staff that provide that care are our primary concerns. (cms.gov)
  • Patients should be counseled about smoking, and they should be warned about the risk of developing mucosal candidiasis after taking medications that impair salivation, antibiotics, corticosteroids, and other immunosuppressants. (medscape.com)
  • Helping societies to better manage risks and shocks will ensure that our development investments are not undermined or destroyed by crises. (oecd.org)
  • Because different types of risks (violence and conflict, natural hazards, economic shocks, etc.) and stressors (such as urbanisation and ageing populations) are complex and interlinked, humanitarian and development actors, along with states, must work together more closely to target vulnerability. (oecd.org)
  • For example, did you know that systemic risks are one of four shocks that all companies will experience in the 2020s? (forrester.com)
  • As a leader in your organisation, you play a vital role in helping everyone understand risks and guiding them to better seize opportunities for the future. (pwc.com)
  • in order to better understand the structural drivers of vulnerability and to adequately address them humanitarian, development and peace and state-building actors need to build a common understanding of risks, capacities and vulnerability in a specific context, to inform response, recovery and development plans. (oecd.org)
  • On demand - by selecting the endpoints from the Network page and send a Risk Scan task from the Tasks menu. (bitdefender.com)
  • Access the Companies View page for an overview of the risk score of all the companies under your management. (bitdefender.com)
  • Risk Management and Climate Change Adaptation will be at- universityadmissions.se. (lu.se)