AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaNamed GroupsHealth Care
RhabdomyosarcomaRhabdomyosarcoma, EmbryonalRhabdomyosarcoma, AlveolarMuscle NeoplasmsPAX7 Transcription FactorPaired Box Transcription FactorsSoft Tissue NeoplasmsOrbital NeoplasmsUrogenital NeoplasmsSarcomaSarcoma, EwingMesenchymomaChromosomes, Human, Pair 13Forkhead Transcription FactorsOncogene Proteins, FusionCombined Modality TherapyTranslocation, GeneticInfant, NewbornChromosomes, Human, Pair 2DesminVincristineVaginal NeoplasmsSertoli-Leydig Cell TumorMyogeninMyoD ProteinCell Line, TumorThoracic NeoplasmsTumor Cells, CulturedChild AbusePrecursor Cell Lymphoblastic Leukemia-LymphomaGene Expression Regulation, NeoplasticPelvic NeoplasmsRisk FactorsDactinomycinAdult Survivors of Child AbusePulmonary BlastomaPrognosisNeoplasmsGene FusionAntineoplastic Combined Chemotherapy ProtocolsChild Abuse, SexualEnterovirus A, HumanNephroblastoma Overexpressed ProteinRetrospective StudiesDisease-Free SurvivalTendonsTomography, X-RayTomography, X-Ray ComputedPelvisBiopsyHernia, VentralBiopsy, NeedleSurgical Mesh
Rhabdomyosarcoma: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)Rhabdomyosarcoma, Embryonal: A form of RHABDOMYOSARCOMA arising primarily in the head and neck, especially the orbit, of children below the age of 10. The cells are smaller than those of other rhabdomyosarcomas and are of two basic cell types: spindle cells and round cells. This cancer is highly sensitive to chemotherapy and has a high cure rate with multi-modality therapy. (From Holland et al., Cancer Medicine, 3d ed, p2188)Rhabdomyosarcoma, Alveolar: A form of RHABDOMYOSARCOMA occurring mainly in adolescents and young adults, affecting muscles of the extremities, trunk, orbital region, etc. It is extremely malignant, metastasizing widely at an early stage. Few cures have been achieved and the prognosis is poor. "Alveolar" refers to its microscopic appearance simulating the cells of the respiratory alveolus. (Holland et al., Cancer Medicine, 3d ed, p2188)Muscle Neoplasms: Tumors or cancer located in muscle tissue or specific muscles. They are differentiated from NEOPLASMS, MUSCLE TISSUE which are neoplasms composed of skeletal, cardiac, or smooth muscle tissue, such as MYOSARCOMA or LEIOMYOMA.PAX7 Transcription Factor: A paired box transcription factor that is involved in EMBRYONIC DEVELOPMENT of the CENTRAL NERVOUS SYSTEM and SKELETAL MUSCLE.Paired Box Transcription Factors: A family of transcription factors that control EMBRYONIC DEVELOPMENT within a variety of cell lineages. They are characterized by a highly conserved paired DNA-binding domain that was first identified in DROSOPHILA segmentation genes.Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.Orbital Neoplasms: Neoplasms of the bony orbit and contents except the eyeball.Urogenital Neoplasms: Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.Sarcoma, Ewing: A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females.Mesenchymoma: A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)Chromosomes, Human, Pair 13: A specific pair of GROUP D CHROMOSOMES of the human chromosome classification.Forkhead Transcription Factors: A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila.Oncogene Proteins, Fusion: The GENETIC TRANSLATION products of the fusion between an ONCOGENE and another gene. The latter may be of viral or cellular origin.Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Translocation, Genetic: A type of chromosome aberration characterized by CHROMOSOME BREAKAGE and transfer of the broken-off portion to another location, often to a different chromosome.Infant, Newborn: An infant during the first month after birth.Chromosomes, Human, Pair 2: A specific pair of human chromosomes in group A (CHROMOSOMES, HUMAN, 1-3) of the human chromosome classification.Desmin: An intermediate filament protein found predominantly in smooth, skeletal, and cardiac muscle cells. Localized at the Z line. MW 50,000 to 55,000 is species dependent.Vincristine: An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)Vaginal Neoplasms: Tumors or cancer of the VAGINA.Sertoli-Leydig Cell Tumor: A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS.Myogenin: A myogenic regulatory factor that controls myogenesis. Myogenin is induced during differentiation of every skeletal muscle cell line that has been investigated, in contrast to the other myogenic regulatory factors that only appear in certain cell types.MyoD Protein: A myogenic regulatory factor that controls myogenesis. Though it is not clear how its function differs from the other myogenic regulatory factors, MyoD appears to be related to fusion and terminal differentiation of the muscle cell.Cell Line, Tumor: A cell line derived from cultured tumor cells.Thoracic NeoplasmsTumor Cells, Cultured: Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.Child Abuse: Abuse of children in a family, institutional, or other setting. (APA, Thesaurus of Psychological Index Terms, 1994)Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Pelvic Neoplasms: Tumors or cancer of the pelvic region.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Dactinomycin: A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)Adult Survivors of Child Abuse: Persons who were child victims of violence and abuse including physical, sexual, or emotional maltreatment.Pulmonary Blastoma: A malignant neoplasm of the lung composed chiefly or entirely of immature undifferentiated cells (i.e., blast forms) with little or virtually no stroma. (From Stedman, 25th ed)Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Gene Fusion: The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Child Abuse, Sexual: Sexual maltreatment of the child or minor.Enterovirus A, Human: A species of ENTEROVIRUS infecting humans and containing 10 serotypes, mostly coxsackieviruses.Nephroblastoma Overexpressed Protein: A CCN protein family member found at high levels in NEPHROBLASTOMA cells. It is found both intracellularly and in the EXTRACELLULAR MATRIX and may play a role in the regulation of CELL PROLIFERATION and EXTRACELLULAR MATRIX synthesis.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Disease-Free Survival: Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.Tendons: Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.Tomography, X-Ray: Tomography using x-ray transmission.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Pelvis: The space or compartment surrounded by the pelvic girdle (bony pelvis). It is subdivided into the greater pelvis and LESSER PELVIS. The pelvic girdle is formed by the PELVIC BONES and SACRUM.Biopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Hernia, Ventral: A hernia caused by weakness of the anterior ABDOMINAL WALL due to midline defects, previous incisions, or increased intra-abdominal pressure. Ventral hernias include UMBILICAL HERNIA, incisional, epigastric, and spigelian hernias.Biopsy, Needle: Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed.Surgical Mesh: Any woven or knit material of open texture used in surgery for the repair, reconstruction, or substitution of tissue. The mesh is usually a synthetic fabric made of various polymers. It is occasionally made of metal.
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaNamed GroupsHealth Care
RhabdomyosarcomaRhabdomyosarcoma, EmbryonalRhabdomyosarcoma, AlveolarMuscle NeoplasmsPAX7 Transcription FactorPaired Box Transcription FactorsSoft Tissue NeoplasmsOrbital NeoplasmsUrogenital NeoplasmsSarcomaSarcoma, EwingMesenchymomaChromosomes, Human, Pair 13Forkhead Transcription FactorsOncogene Proteins, FusionCombined Modality TherapyTranslocation, GeneticInfant, NewbornChromosomes, Human, Pair 2DesminVincristineVaginal NeoplasmsSertoli-Leydig Cell TumorMyogeninMyoD ProteinCell Line, TumorThoracic NeoplasmsTumor Cells, CulturedChild AbusePrecursor Cell Lymphoblastic Leukemia-LymphomaGene Expression Regulation, NeoplasticPelvic NeoplasmsRisk FactorsDactinomycinAdult Survivors of Child AbusePulmonary BlastomaPrognosisNeoplasmsGene FusionAntineoplastic Combined Chemotherapy ProtocolsChild Abuse, SexualEnterovirus A, HumanNephroblastoma Overexpressed ProteinRetrospective StudiesDisease-Free SurvivalTendonsTomography, X-RayTomography, X-Ray ComputedPelvisBiopsyHernia, VentralBiopsy, NeedleSurgical Mesh
VinorelbineVinorelbine
"Vinorelbine in previously treated advanced childhood sarcomas: Evidence of activity in rhabdomyosarcoma". Cancer. 94 (12): 3263 ... It is also active in rhabdomyosarcoma. Vinorelbine has a number of side-effects that can limit its use: Chemotherapy-induced ...
Malignant rhabdoid tumourMalignant rhabdoid tumour
MRTs are a rare and highly malignant childhood neoplasm. Later rhabdoid tumours outside the kidney were reported in many ... The term rhabdoid was used due to its similarity with rhabdomyosarcoma under the light microscope. The exact pathogenesis of ...
Li-Fraumeni syndromeLi-Fraumeni syndrome
Li and Fraumeni identified four families in which siblings or cousins of rhabdomyosarcoma patients had a childhood sarcoma, ... who first recognized the syndrome after reviewing the medical records and death certificates of 648 childhood rhabdomyosarcoma ... 80% of children with adrenocortical carcinoma and 2%-10% of childhood brain tumors have p53 mutations. 2%-3% of osteosarcomas, ... July 2013). "Impact of neonatal screening and surveillance for the TP53 R337H mutation on early detection of childhood ...
Childrens Oncology GroupChildren's Oncology Group
... studied a diverse array of childhood cancers, while two others, the Intergroup Rhabdomyosarcoma Study Group (IRSG) and the ... The cooperative group system for clinical research began in 1955 with a consortium focused on childhood cancer research. By the ... Central nervous system (brain) tumors are the second most common form of childhood cancer. COG conducts research in children ... The large multi-site structure of COG also allows it to conduct research into very rare childhood cancer including ...
Costello syndromeCostello syndrome
It is a RASopathy.[citation needed] Beginning in early childhood, people with Costello syndrome have an increased risk of ... The most frequent cancerous tumor associated with Costello syndrome is a soft tissue tumor called a rhabdomyosarcoma. Other ...
List of vaginal tumorsList of vaginal tumors
PDQ Pediatric Treatment Editorial Board (2018). PDQ Cancer Information Summaries - Childhood Rhabdomyosarcoma Treatment. ... Mierau GW, Lovell MA, Wyatt-Ashmead J, Goin L (May 2005). "Benign müllerian papilloma of childhood". Ultrastructural Pathology ... "Progress in the surgical management of vaginal rhabdomyosarcoma: a 25-year review from the Intergroup Rhabdomyosarcoma Study ...
Pediatric surgeryPediatric surgery
... pectus excavatum childhood tumors: like neuroblastoma, Wilms' tumor, rhabdomyosarcoma, ATRT, liver tumors, teratomas Separation ... childhood cancer) surgery. Common pediatric diseases that may require pediatric surgery include: congenital malformations: ...
Childhood cancerChildhood cancer
Childhood rhabdomyosarcoma (3%, many sites) Retinoblastoma (3%, eye) Osteosarcoma (3%, bone cancer) Ewing sarcoma (1%, many ... Childhood cancer (also known as pediatric cancer) is cancer in a child. In the United States, an arbitrarily adopted standard ... In developed countries, childhood cancer has a mortality of approximately 20% of cases. In low resource settings, on the other ... Other, less common childhood cancer types are: Neuroblastoma (6%, nervous system) Wilms tumor (5%, kidney) Non-Hodgkin lymphoma ...
RhabdomyosarcomaRhabdomyosarcoma
"Pretreatment TNM staging of childhood rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Study Group. Children's ... Ognjanovic, Simona; Linabery, Amy M.; Charbonneau, Bridget; Ross, Julie A. (2009-09-15). "Trends in childhood rhabdomyosarcoma ... PDQ Pediatric Treatment Editorial Board (2002-01-01). Childhood Rhabdomyosarcoma Treatment (PDQ®): Health Professional Version ... However, rhabdomyosarcoma can be generally divided into three histological subsets: Embryonal rhabdomyosarcoma (ERMS) is the ...
VinorelbineVinorelbine
"Vinorelbine in previously treated advanced childhood sarcomas: Evidence of activity in rhabdomyosarcoma". Cancer. 94 (12): 3263 ...
Childhood rhabdomyosarcomaChildhood rhabdomyosarcoma
... Treatment Bethesda, MD. "Childhood Rhabdomyosarcoma Treatment". PDQ (NCI). Missing or empty ,url= ( ... Childhood rhabdomyosarcoma is a cancer that develops out of the cells that form skeletal muscles. These cells are called ... Childhood rhabdomyosarcoma consists of three subgroups. Embryonal is the most common among children and young adults. Alveolar ... Anaplastic rhabdomyosarcoma is rarely seen in children and only precise intensive lab work can identify it. Childhood ...
Intergroup Rhabdomyosarcoma Study GroupIntergroup Rhabdomyosarcoma Study Group
... and Canadian clinical trial cooperative group created with the mission of studying childhood cancers. In 2000, IRS merged with ... The Intergroup Rhabdomyosarcoma Study Group used to have all of its protocol driven cases reviewed at the Quality Assurance ... The Intergroup Rhabdomyosarcoma Study Group (IRS) was a U.S. ... "Results of the Intergroup Rhabdomyosarcoma Study Group D9602 ... "The Intergroup Rhabdomyosarcoma Study Group (IRSG): Major Lessons From the IRS-I Through IRS-IV Studies as Background for the ...
Li-Fraumeni syndromeLi-Fraumeni syndrome
Li and Fraumeni identified four families in which siblings or cousins of rhabdomyosarcoma patients had a childhood sarcoma, ... who first recognized the syndrome after reviewing the medical records and death certificates of 648 childhood rhabdomyosarcoma ... a proband with any childhood cancer or sarcoma, brain tumor or adrenal cortical carcinoma diagnosed before age 45 ... 80% of children with adrenocortical carcinoma and 2%-10% of childhood brain tumors have p53 mutations. ...
Mismatch repair cancer syndromeMismatch repair cancer syndrome
... "childhood cancer syndrome" has also been proposed.Café-au-lait macules have been observed. Familial adenomatous polyposis + ... "Rhabdomyosarcoma in patients with constitutional mismatch-repair-deficiency syndrome". Journal of Medical Genetics. 46 (6): 418 ... "Biallelic PMS2 mutations and a distinctive childhood cancer syndrome". Journal of Pediatric Hematology/Oncology. 30 (3): 254-7 ...
Beckwith-Wiedemann syndromeBeckwith-Wiedemann syndrome
While children with BWS are at increased risk of childhood cancer, most children with BWS do not develop cancer and the vast ... rhabdomyosarcoma, and mesoblastic nephroma. Wilms tumor, hepatoblastoma, and mesoblastic nephroma can usually be cured if ... Individuals with BWS appear to only be at increased risk for cancer during childhood (especially before age four) and do not ... Children with BWS are most at risk during early childhood and should receive cancer screening during this time. In general, ...
In vitro fertilisationIn vitro fertilisation
Overall, IVF does not cause an increased risk of childhood cancer.[49] Studies have shown a decrease in the risk of certain ... cancers and an increased risks of certain others including retinoblastoma[50] hepatoblastoma[49] and rhabdomyosarcoma.[49] ...
Mark StaniszewskiMark Staniszewski
... he began training Brazilian Jiu-Jitsu in the garage of childhood friend and former UFC champion Matt Serra. Finding them to be ... Stage 4 Alveolar Rhabdomyosarcoma). The judo, Brazilian Jiu-Jitsu and wrestling communities rallied around the Staniszewski ...
Desmoplastic small-round-cell tumorDesmoplastic small-round-cell tumor
The tumor appears to arise from the primitive cells of childhood, and is considered a childhood cancer. Research has indicated ... DSRCT in young patients can be mistaken for other abdominal tumors including rhabdomyosarcoma, neuroblastoma, and mesenteric ... It is considered a childhood cancer that predominantly strikes boys and young adults. The disease rarely occurs in females, but ... rhabdomyosarcoma, and Wilms' tumor. DSRCT is frequently misdiagnosed. Adult patients should always be referred to a sarcoma ...
Epithelioid sarcomaEpithelioid sarcoma
"Secondary Sarcomas in Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study". Journal of the National ... "Non-metastatic unresected paediatric non-rhabdomyosarcoma soft tissue sarcomas: Results of a pooled analysis from United States ... Rao, Bhaskar N.; Rodriguez-Galindo, Carlos (2003). "Local control in childhood extremity sarcomas: Salvaging limbs and sparing ... "Late Cardiac Effects of Doxorubicin Therapy for Acute Lymphoblastic Leukemia in Childhood". New England Journal of Medicine. ...
Sharon WeissSharon Weiss
Sclerosing Rhabdomyosarcoma (2002) Spindle cell hemangioma (formerly spindle cell hemangioendothelioma)(1986) List of ... "Kaposiform Hemangioendothelioma of Infancy and Childhood: An Aggressive Neoplasm Associated with Kasabach-Merritt Syndrome and ...
List of diseases (R)List of diseases (R)
Rhabdomyomatous dysplasia cardiopathy genital anomalies Rhabdomyosarcoma Rhabdomyosarcoma 1 Rhabdomyosarcoma 2 Rhabdomyosarcoma ... Reactive attachment disorder of early childhood Reactive attachment disorder of infancy Reactive hypoglycemia Reardon-Hall- ... alveolar Rhabdomyosarcoma, embryonal Rheumatic fever Rheumatism Rheumatoid arthritis Rheumatoid purpura Rheumatoid vasculitis ...
EctomesenchymomaEctomesenchymoma
Mouton SC, Rosenberg HS, Cohen MC, Drut R, Emms M, Kaschula RO (1996) Malignant ectomesenchymoma in childhood. Pediat Pathol ... Differential diagnosis should consider rhabdomyosarcoma, Triton tumor, teratoma, Wilms tumor and benign, mature ... usually rhabdomyosarcoma . The most accepted theory suggests that this tumor arises from remnants of migratory neural crest ... a finding in common with alveolar rhabdomyosarcoma. They found as well 2 distinctive chromosome 6p21.32-p21.2 and 6p11.2 ...
Mark SanchezMark Sanchez
Mark's father remarried and raised them strictly, seeking to influence them to become leaders.[4][5] Throughout his childhood ... a terminally ill 11-year-old struck with rhabdomyosarcoma. Sanchez developed a bond with Binkley and the two remained close ... helps raise awareness about childhood obesity and how families can prevent it.[135][136] Sanchez has also worked with the Teddy ...
EnterovirusEnterovirus
Hand, foot and mouth disease is a childhood illness most commonly caused by infection by Coxsackie A virus or EV71. ... Lin TY, Chu C, Chiu CH (2002). "Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in ...
Sacrococcygeal teratomaSacrococcygeal teratoma
Engelskirchen R, Holschneider AM, Rhein R, Hecker WC, Höpner F (1987). "[Sacral teratomas in childhood. An analysis of long- ... These include extraspinal ependymoma, ependymoblastoma, neuroblastoma and rhabdomyosarcoma. Smaller SCTs with an external ...
Eye neoplasmEye neoplasm
Tumors in the eye and orbit can be benign like dermoid cysts, or malignant like rhabdomyosarcoma and retinoblastoma. ... Cancer.Net: Retinoblastoma, Childhood. Retrieved from "https://en.wikipedia.org/w/index.php?title=Eye_neoplasm&oldid=895356793" ...
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaNamed GroupsHealth Care
RhabdomyosarcomaRhabdomyosarcoma, EmbryonalRhabdomyosarcoma, AlveolarMuscle NeoplasmsPAX7 Transcription FactorPaired Box Transcription FactorsSoft Tissue NeoplasmsOrbital NeoplasmsUrogenital NeoplasmsSarcomaSarcoma, EwingMesenchymomaChromosomes, Human, Pair 13Forkhead Transcription FactorsOncogene Proteins, FusionCombined Modality TherapyTranslocation, GeneticInfant, NewbornChromosomes, Human, Pair 2DesminVincristineVaginal NeoplasmsSertoli-Leydig Cell TumorMyogeninMyoD ProteinCell Line, TumorThoracic NeoplasmsTumor Cells, CulturedChild AbusePrecursor Cell Lymphoblastic Leukemia-LymphomaGene Expression Regulation, NeoplasticPelvic NeoplasmsRisk FactorsDactinomycinAdult Survivors of Child AbusePulmonary BlastomaPrognosisNeoplasmsGene FusionAntineoplastic Combined Chemotherapy ProtocolsChild Abuse, SexualEnterovirus A, HumanNephroblastoma Overexpressed ProteinRetrospective StudiesDisease-Free SurvivalTendonsTomography, X-RayTomography, X-Ray ComputedPelvisBiopsyHernia, VentralBiopsy, NeedleSurgical Mesh
Sci. Pharm. | Free Full-Text | Integrin- and IGF1-Receptor-Mediated Liposomal siRNA Delivery to Alveolar Rhabdomyosarcoma CellsSci. Pharm. | Free Full-Text | Integrin- and IGF1-Receptor-Mediated Liposomal siRNA Delivery to Alveolar Rhabdomyosarcoma Cells
Especially the alveolar rhabdomyosarcoma (ARMS) shows poor prognosis when metastases have developed. [...] ... Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. ... Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Especially the alveolar rhabdomyosarcoma (ARMS) shows ... Integrin- and IGF1-Receptor-Mediated Liposomal siRNA Delivery to Alveolar Rhabdomyosarcoma Cells. S. STRIEPE 1,* , J. RÖSSLER 2 ...
mdpi.com
Sarcoma Awareness Month - ACCOSarcoma Awareness Month - ACCO
Rhabdomyosarcoma accounts for 5-8% of childhood cancers.. *70% of all rhabdomyosarcoma cases diagnosed in the first ten years ... The American Childhood Cancer Organization is a 501(c)(3) public charity, whose programs and services are funded entirely by ... Rhabdomyosarcoma accounts for about half of the cases of pediatric soft tissue sarcomas. Less frequent pediatric soft tissue ...
acco.org
Childhood rhabdomyosarcoma - WikipediaChildhood rhabdomyosarcoma - Wikipedia
Childhood Rhabdomyosarcoma Treatment Bethesda, MD. "Childhood Rhabdomyosarcoma Treatment". PDQ (NCI). Missing or empty ,url= ( ... Childhood rhabdomyosarcoma is a cancer that develops out of the cells that form skeletal muscles. These cells are called ... Childhood rhabdomyosarcoma consists of three subgroups. Embryonal is the most common among children and young adults. Alveolar ... Anaplastic rhabdomyosarcoma is rarely seen in children and only precise intensive lab work can identify it. Childhood ...
en.wikipedia.org
Rhabdomyosarcoma - Childhood: Types of Treatment | Cancer.NetRhabdomyosarcoma - Childhood: Types of Treatment | Cancer.Net
You will learn about the different types of treatments doctors use for children with rhabdomyosarcoma. Use the menu to see ... Rhabdomyosarcoma - Childhood: Types of Treatment. Approved by the Cancer.Net Editorial Board, 10/2018 ... In the United States, most research on childhood rhabdomyosarcoma takes place through the COG. Other individual hospitals may ... Surgery is usually the first treatment for childhood rhabdomyosarcoma, unless there is distant metastases. However, even ...
cancer.net
Rhabdomyosarcoma - Childhood: Stages and Groups | Cancer.NetRhabdomyosarcoma - Childhood: Stages and Groups | Cancer.Net
Rhabdomyosarcoma - Childhood: Stages and Groups. Rhabdomyosarcoma - Childhood: Stages and Groups. Approved by the Cancer.Net ... The Intergroup Rhabdomyosarcoma Studies (IRS) designed the following grouping and staging guidelines:. Group I: Describes a ... Doctors use a grouping and staging system to describe rhabdomyosarcoma. Staging is a way of describing where the cancer is ...
cancer.net
Childhood Rhabdomyosarcoma Treatment (PDQ®) (Health professionals) | OncoLinkChildhood Rhabdomyosarcoma Treatment (PDQ®) (Health professionals) | OncoLink
Childhood Rhabdomyosarcoma Treatment. childhood rhabdomyosarcoma. General Information About Childhood Rhabdomyosarcoma. ... childhood rhabdomyosarcoma. Cellular Classification for Childhood Rhabdomyosarcoma. Histologic Subtypes. Rhabdomyosarcoma can ... childhood rhabdomyosarcoma. Stage Information for Childhood Rhabdomyosarcoma. Staging Evaluation. Before a biopsy of a ... childhood rhabdomyosarcoma. Treatment Option Overview for Childhood Rhabdomyosarcoma. Multimodality Therapy. All children with ...
oncolink.org
Rhabdomyosarcoma | Alexs Lemonade Stand Foundation for Childhood CancerRhabdomyosarcoma | Alex's Lemonade Stand Foundation for Childhood Cancer
There are several types of RMS including: embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma, anaplastic rhabdomyosarcoma ... Rhabdomyosarcoma (RMS) is a cancer that develops from the cells that normally develop into skeletal muscles. RMS commonly ... There are several types of RMS including: embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma, anaplastic rhabdomyosarcoma ... Rhabdomyosarcoma. Rhabdomyosarcoma (RMS) is a cancer that develops from the cells that normally develop into skeletal muscles. ...
alexslemonade.org
alveolar rhabdomyosarcoma | St. Baldricks Blog | Childhood Cancer Stories & Researchalveolar rhabdomyosarcoma | St. Baldrick's Blog | Childhood Cancer Stories & Research
Read our blog to learn more about childhood cancer, lifesaving research, inspiring families, and how the foundation is making a ... What is alveolar rhabdomyosarcoma?. There are two main types of pediatric rhabdomyosarcoma: embryonal rhabdomyosarcoma and ... Katie is now in treatment for alveolar rhabdomyosarcoma, a type of childhood cancer. ... What Is Alveolar Rhabdomyosarcoma?. by St. Baldricks Foundation May 13, 2013 Scott Diede, M.D., Ph.D., a St. Baldricks ...
stbaldricks.org
Childhood cancer treatment optimization: In rhabdomyosarcoma and supportive careChildhood cancer treatment optimization: In rhabdomyosarcoma and supportive care
... Supervisors. H.N. Caron. ... rhabdomyosarcoma. In the last chapters adverse events following local treatment in head and neck rhabdomyosarcoma are described ... In the majority of head and neck rhabdomyosarcoma patients radiotherapy is needed to achieve and maintain local control. ... related complications and improvement of local treatment in head and neck rhabdomyosarcoma survivors. Central venous catheters ...
dare.uva.nl
Childhood Rhabdomyosarcoma Treatment (PDQ®): Treatment - Patient Information [NCI]Childhood Rhabdomyosarcoma Treatment (PDQ®): Treatment - Patient Information [NCI]
Rhabdomyosarcoma is a type of sarcoma. Sarcoma is cancer of soft tissue (such as muscle), connective tissue (such as tendon or ... Rhabdomyosarcoma usually begins in muscles that are attached to bones and... ... Childhood rhabdomyosarcoma is a disease in which malignant (cancer) cells form in muscle tissue. ... Childhood Rhabdomyosarcoma Treatment. General Information About Childhood Rhabdomyosarcoma. Childhood rhabdomyosarcoma is a ...
cardiosmart.org
Childhood Rhabdomyosarcoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Adventist HealthCareChildhood Rhabdomyosarcoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Adventist HealthCare
Rhabdomyosarcoma is a type of sarcoma. Sarcoma is cancer of soft tissue (such as muscle), connective tissue (such as tendon or ... Rhabdomyosarcoma usually begins in muscles that are attached to bones and... ... Childhood rhabdomyosarcoma is a disease in which malignant (cancer) cells form in muscle tissue. ... Staging of childhood rhabdomyosarcoma is done in three parts.. Childhood rhabdomyosarcoma is staged by using three different ...
adventisthealthcare.com
Role of the macro lncRNA KCNQ1OT1 in embryonal rhabdomyosarcoma tumorigenesis | Alexs Lemonade Stand Foundation for Childhood...Role of the macro lncRNA KCNQ1OT1 in embryonal rhabdomyosarcoma tumorigenesis | Alex's Lemonade Stand Foundation for Childhood...
... and the most common soft tissue connective cancer of childhood. While the medical community has made great strides in improving ... Embryonal rhabdomyosarcoma (ERMS) is a soft tissue cancer with features of skeletal muscle, ... Home » Where the Money Goes » ALSF Funded Projects » Role of the macro lncRNA KCNQ1OT1 in embryonal rhabdomyosarcoma ... Embryonal rhabdomyosarcoma (ERMS) is a soft tissue cancer with features of skeletal muscle, and the most common soft tissue ...
alexslemonade.org
GENERIC childhood rhabdomyosarcomaGENERIC childhood rhabdomyosarcoma
NCI: An aggressive malignant mesenchymal neoplasm arising from skeletal muscle in children. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites. ...
linkedlifedata.com
What is the prognosis of Childhood Rhabdomyosarcoma? | CancerWhat is the prognosis of Childhood Rhabdomyosarcoma? | Cancer
Childhood rhabdomyosarcoma is a medical condition characterised by malignant (cancer) cells forming in muscle tissues. The size ... One of the possible signs of childhood rhabdomyosarcoma is a lump or swelling that keeps getting bigger. Among other signs are ... What is the Prognosis of Childhood Rhabdomyosarcoma?. Cancer By Himanshu Sharma , Onlymyhealth editorial team / Aug 09, 2018 ... Childhood rhabdomyosarcoma is a medical condition characterised by malignant (cancer) cells forming in muscle tissues. It is a ...
onlymyhealth.com
What is the diagnosis of Childhood Rhabdomyosarcoma? | Childhood Rhabdomyosarcoma Diagnosis and PrognosisWhat is the diagnosis of Childhood Rhabdomyosarcoma? | Childhood Rhabdomyosarcoma Diagnosis and Prognosis
What are the symptoms of Childhood Rhabdomyosarcoma? Childhood rhabdomyosarcoma is a medical condition characterised by ... What is the prognosis of Childhood Rhabdomyosarcoma? Childhood rhabdomyosarcoma is a medical condition characterised by ... What is the diagnosis of Childhood Rhabdomyosarcoma?. By NIH , National Institute of Health ... Tests that examine the area of the body with symptoms are used to detect (find) and diagnose childhood rhabdomyosarcoma. ...
onlymyhealth.com
Rhabdomyosarcoma - Pediatric Cancer Treatment - Dana-Farber Cancer Institute | Boston, MARhabdomyosarcoma - Pediatric Cancer Treatment - Dana-Farber Cancer Institute | Boston, MA
Learn about rhabdomyosarcoma and find information on how we support and care for children and teens with rhabdomyosarcoma ... Rhabdomyosarcoma is a cancer that forms in the soft tissues in a type of muscle called striated muscle. ... What Is Childhood Rhabdomyosarcoma?. * Rhabdomyosarcoma is a cancerous tumor that grows in the bodys soft tissues (which ... Learn more about rhabdomyosarcoma. Find in-depth details on rhabdomyosarcoma on the Dana-Farber/Boston Childrens website, ...
dana-farber.org
Sarcoma in Children | Ewing, Rhabdomyosarcoma, Osteosarcoma | Duke HealthSarcoma in Children | Ewing, Rhabdomyosarcoma, Osteosarcoma | Duke Health
Childhood Cancer Survivorship Care Once treatment is complete, you can count on us for continuing support. We offer long-term ... Sarcoma is cancer that affects connective tissue, including muscle (rhabdomyosarcoma) and bone (osteosarcoma and Ewing sarcoma ... the worlds largest childhood and adolescent cancer research organization. That means your child gets the combined expertise of ...
dukehealth.org
Rhabdomyosarcoma | Vanderbilt-Ingram Cancer CenterRhabdomyosarcoma | Vanderbilt-Ingram Cancer Center
Low-risk childhood rhabdomyosarcoma. Low-risk childhood rhabdomyosarcoma is one of the following:. *An embryonal tumor of any ... General Information About Childhood Rhabdomyosarcoma. Go to Health Professional Version Key Points. *Childhood rhabdomyosarcoma ... Stages of Childhood Rhabdomyosarcoma. Key Points. *After childhood rhabdomyosarcoma has been diagnosed, treatment is based in ... Recurrent Childhood Rhabdomyosarcoma. Recurrent childhood rhabdomyosarcoma is cancer that has recurred (come back) after it has ...
vicc.org
Which histologic findings are characteristic of pediatric rhabdomyosarcoma (RMS)?Which histologic findings are characteristic of pediatric rhabdomyosarcoma (RMS)?
Pretreatment TNM staging of childhood rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Study Group. Childrens ... Childhood rhabdomyosarcoma. Anatomo-clinical and therapeutic study on 25 cases. Surgical implications. Rom J Morphol Embryol. ... Prevalence and clinical impact of anaplasia in childhood rhabdomyosarcoma : a report from the Soft Tissue Sarcoma Committee of ... Vinorelbine in previously treated advanced childhood sarcomas: evidence of activity in rhabdomyosarcoma. Cancer. 2002 Jun 15. ...
medscape.com
What is the pathophysiology of pediatric rhabdomyosarcoma (RMS)?What is the pathophysiology of pediatric rhabdomyosarcoma (RMS)?
Five variants of rhabdomyosarcoma are described in the international classificat... more ... Pretreatment TNM staging of childhood rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Study Group. Childrens ... Childhood rhabdomyosarcoma. Anatomo-clinical and therapeutic study on 25 cases. Surgical implications. Rom J Morphol Embryol. ... Prevalence and clinical impact of anaplasia in childhood rhabdomyosarcoma : a report from the Soft Tissue Sarcoma Committee of ...
medscape.com
Results of a prospective study of the treatment of rhabdomyosarcoma in childhood]. - Semantic ScholarResults of a prospective study of the treatment of rhabdomyosarcoma in childhood]. - Semantic Scholar
Results of a prospective study of the treatment of rhabdomyosarcoma in childhood]. by Ulrich Willnow et al. ... Results of a prospective study of the treatment of rhabdomyosarcoma in childhood].. *. Ulrich Willnow, Hans Lindner, Karin ... article{Willnow1986ResultsOA, title={[Results of a prospective study of the treatment of rhabdomyosarcoma in childhood].}, ...
semanticscholar.org
Rhabdomyosarcoma Stages and Risk GroupsRhabdomyosarcoma Stages and Risk Groups
Childhood Rhabdomyosarcoma Treatment (PDQ®). 2018. Accessed at www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma- ... Rhabdomyosarcoma Stages and Risk Groups. Once rhabdomyosarcoma (RMS) has been diagnosed and the type of RMS identified, doctors ... Accessed at www.uptodate.com/contents/rhabdomyosarcoma-in-childhood-and-adolescence-epidemiology-pathology-and-molecular- ... Okcu MF, Hicks J. Rhabdomyosarcoma in childhood and adolescence: Epidemiology, pathology, and molecular pathogenesis. UpToDate ...
cancer.org
Whats New in Rhabdomyosarcoma Research?What's New in Rhabdomyosarcoma Research?
... largely due to the work of the Intergroup Rhabdomyosarcoma Study Group (now known as the Soft Tissue Sarcoma Committee of the ... The treatment of rhabdomyosarcoma has come a long way in the past 30 years, ... Childhood Rhabdomyosarcoma Treatment (PDQ®). 2018. Accessed at www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma- ... Rhabdomyosarcoma in childhood and adolescence: Treatment. UpToDate. Accessed at www.uptodate.com/contents/rhabdomyosarcoma-in- ...
cancer.org
Pediatric Rhabdomyosarcoma Surgery Differential DiagnosesPediatric Rhabdomyosarcoma Surgery Differential Diagnoses
Rhabdomyosarcoma is a malignancy that arises from embryonic mesenchymal cells that possess the potential to develop into ... Pretreatment TNM staging of childhood rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Study Group. Childrens ... Childhood rhabdomyosarcoma. Anatomo-clinical and therapeutic study on 25 cases. Surgical implications. Rom J Morphol Embryol. ... Prevalence and clinical impact of anaplasia in childhood rhabdomyosarcoma : a report from the Soft Tissue Sarcoma Committee of ...
emedicine.medscape.com
A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma - Full Text View - ClinicalTrials.govA Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma - Full Text View - ClinicalTrials.gov
Genetic and Rare Diseases Information Center resources: Medulloblastoma Medulloblastoma, Childhood Soft Tissue Sarcoma Glioma ... A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma. This study has been withdrawn prior to enrollment. ... Rhabdomyosarcoma. Medulloblastoma. Myosarcoma. Neoplasms, Muscle Tissue. Neoplasms, Connective and Soft Tissue. Neoplasms by ... For Part A: Have a diagnosis of recurrent or refractory rhabdomyosarcoma or medulloblastoma and have had histologic ...
clinicaltrials.gov
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaNamed GroupsHealth Care
RhabdomyosarcomaRhabdomyosarcoma, EmbryonalRhabdomyosarcoma, AlveolarMuscle NeoplasmsPAX7 Transcription FactorPaired Box Transcription FactorsSoft Tissue NeoplasmsOrbital NeoplasmsUrogenital NeoplasmsSarcomaSarcoma, EwingMesenchymomaChromosomes, Human, Pair 13Forkhead Transcription FactorsOncogene Proteins, FusionCombined Modality TherapyTranslocation, GeneticInfant, NewbornChromosomes, Human, Pair 2DesminVincristineVaginal NeoplasmsSertoli-Leydig Cell TumorMyogeninMyoD ProteinCell Line, TumorThoracic NeoplasmsTumor Cells, CulturedChild AbusePrecursor Cell Lymphoblastic Leukemia-LymphomaGene Expression Regulation, NeoplasticPelvic NeoplasmsRisk FactorsDactinomycinAdult Survivors of Child AbusePulmonary BlastomaPrognosisNeoplasmsGene FusionAntineoplastic Combined Chemotherapy ProtocolsChild Abuse, SexualEnterovirus A, HumanNephroblastoma Overexpressed ProteinRetrospective StudiesDisease-Free SurvivalTendonsTomography, X-RayTomography, X-Ray ComputedPelvisBiopsyHernia, VentralBiopsy, NeedleSurgical Mesh
CancersSarcomasCases diagnosedChildrenOrganizationEmbryonal rhabdomyosarcomaSarcomaPrognosisAnaplastic rhabdomyosarcomaChemotherapySubtypeCases of rhabdomyosarcoma2018OsteosarcomaTreat rhabdomyosarcomaSymptomsDiagnosisAcute LeukemiaAggressiveOccurHigh-risk rhabdomyosarcomaIntergroup Rhabdomyosarcoma StudiesArmsSkeletalBoneHistologicChild has rhabdomyosarcomaPax3GeneticPrognosticSpindle cellCause rhabdomyosarcomaOrbital rhabdomyosarcomaAlveolar rhabdomyosarcomasIncidenceClinicalAdultsIRSGTreatment of childhoodCancer survivorsStages
Cancers1
Sarcomas1
Cases diagnosed1
Children1
Organization1
  • The American Childhood Cancer Organization is a 501(c)(3) public charity, whose programs and services are funded entirely by private donations, foundation grants, and corporate contributions. (acco.org)
Embryonal rhabdomyosarcoma23
Sarcoma23
Prognosis6
Anaplastic rhabdomyosarcoma2
Chemotherapy15
Subtype2
Cases of rhabdomyosarcoma3
20181
Osteosarcoma1
Treat rhabdomyosarcoma3
Symptoms14
Diagnosis7
Acute Leukemia2
Aggressive10
Occur4
High-risk rhabdomyosarcoma1
  • Determine the safety and feasibility of administering maintenance therapy comprising irinotecan to patients with high-risk rhabdomyosarcoma treated with this regimen. (knowcancer.com)
Intergroup Rhabdomyosarcoma Studies1
Arms4
Skeletal5
Bone3
Histologic2
Child has rhabdomyosarcoma1
Pax37
Genetic2
Prognostic2
Spindle cell1
Cause rhabdomyosarcoma2
Orbital rhabdomyosarcoma2
Alveolar rhabdomyosarcomas2
Incidence3
Clinical4
Adults1
IRSG2
Treatment of childhood2
Cancer survivors5
Stages3