Academies and Institutes: Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.National Human Genome Research Institute (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports research into the mapping of the human genome and other organism genomes. The National Center for Human Genome Research was established in 1989 and re-named the National Human Genome Research Institute in 1997.Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Research Support as Topic: Financial support of research activities.Awards and PrizesResearch Personnel: Those individuals engaged in research.Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.National Institutes of Health (U.S.): An operating division of the US Department of Health and Human Services. It is concerned with the overall planning, promoting, and administering of programs pertaining to health and medical research. Until 1995, it was an agency of the United States PUBLIC HEALTH SERVICE.Coronary Thrombosis: Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.Translational Medical Research: The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.United StatesSinus Thrombosis, Intracranial: Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.Comparative Effectiveness Research: Conduct and synthesis of systematic research comparing interventions and strategies to prevent, diagnose, treat, and monitor health conditions. The purpose of this research is to inform patients, providers, and decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. (hhs.gov/recovery/programs/cer/draftdefinition.html accessed 6/12/2009)History, 20th Century: Time period from 1901 through 2000 of the common era.Research Design: A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.Guidelines as Topic: A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.Intracranial Thrombosis: Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.TaiwanPatient-Centered Care: Design of patient care wherein institutional resources and personnel are organized around patients rather than around specialized departments. (From Hospitals 1993 Feb 5;67(3):14)IndiaCarotid Artery Thrombosis: Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.International Cooperation: The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Great BritainClinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Institute of Medicine (U.S.): Identifies, for study and analysis, important issues and problems that relate to health and medicine. The Institute initiates and conducts studies of national policy and planning for health care and health-related education and research; it also responds to requests from the federal government and other agencies for studies and advice.Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Outcome Assessment (Health Care): Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).National Cancer Institute (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. Through basic and clinical biomedical research and training, it conducts and supports research with the objective of cancer prevention, early stage identification and elimination. This Institute was established in 1937.Anticoagulants: Agents that prevent clotting.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Ethics, Research: The moral obligations governing the conduct of research. Used for discussions of research ethics as a general topic.Genome-Wide Association Study: An analysis comparing the allele frequencies of all available (or a whole GENOME representative set of) polymorphic markers in unrelated patients with a specific symptom or disease condition, and those of healthy controls to identify markers associated with a specific disease or condition.Sagittal Sinus Thrombosis: Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA.Phlebography: Radiographic visualization or recording of a vein after the injection of contrast medium.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Intracranial Embolism and Thrombosis: Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.Nursing Research: Research carried out by nurses, generally in clinical settings, in the areas of clinical practice, evaluation, nursing education, nursing administration, and methodology.National Heart, Lung, and Blood Institute (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports research program related to diseases of the heart, blood vessels, lung, and blood; blood resources; and SLEEP WAKE DISORDERS. From 1948 until October 10, 1969, it was known as the National Heart Institute. From June 25, 1976, it was the National Heart and Lung Institute. Since October 1997, the NHLBI has also had administrative responsibility for the NIH Woman's Health Initiative.Iliac Vein: A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.Thrombophilia: A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.Femoral Vein: The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.Upper Extremity Deep Vein Thrombosis: DEEP VEIN THROMBOSIS of an upper extremity vein (e.g., AXILLARY VEIN; SUBCLAVIAN VEIN; and JUGULAR VEINS). It is associated with mechanical factors (Upper Extremity Deep Vein Thrombosis, Primary) secondary to other anatomic factors (Upper Extremity Deep Vein Thrombosis, Secondary). Symptoms may include sudden onset of pain, warmth, redness, blueness, and swelling in the arm.Health Services Research: The integration of epidemiologic, sociological, economic, and other analytic sciences in the study of health services. Health services research is usually concerned with relationships between need, demand, supply, use, and outcome of health services. The aim of the research is evaluation, particularly in terms of structure, process, output, and outcome. (From Last, Dictionary of Epidemiology, 2d ed)Fibrinolytic Agents: Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Cerebral Veins: Veins draining the cerebrum.Genetic Research: Research into the cause, transmission, amelioration, elimination, or enhancement of inherited disorders and traits.National Institute of Mental Health (U.S.): A component of the NATIONAL INSTITUTES OF HEALTH concerned with research, overall planning, promoting, and administering mental health programs and research. It was established in 1949.Heparin: A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.Factor V: Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.Hemostasis: The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.Heparin, Low-Molecular-Weight: Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.Cavernous Sinus Thrombosis: Formation or presence of a blood clot (THROMBUS) in the CAVERNOUS SINUS of the brain. Infections of the paranasal sinuses and adjacent structures, CRANIOCEREBRAL TRAUMA, and THROMBOPHILIA are associated conditions. Clinical manifestations include dysfunction of cranial nerves III, IV, V, and VI, marked periorbital swelling, chemosis, fever, and visual loss. (From Adams et al., Principles of Neurology, 6th ed, p711)Blood Coagulation: The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.Platelet Aggregation Inhibitors: Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.Antiphospholipid Syndrome: The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).Vena Cava, Inferior: The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.Thrombectomy: Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.National Institute for Occupational Safety and Health (U.S.): An institute of the CENTERS FOR DISEASE CONTROL AND PREVENTION which is responsible for assuring safe and healthful working conditions and for developing standards of safety and health. Research activities are carried out pertinent to these goals.Lateral Sinus Thrombosis: Formation or presence of a blood clot (THROMBUS) in the LATERAL SINUSES. This condition is often associated with ear infections (OTITIS MEDIA or MASTOIDITIS) without antibiotic treatment. In developed nations, lateral sinus thrombosis can result from CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; NEUROSURGICAL PROCEDURES; THROMBOPHILIA; and other conditions. Clinical features include HEADACHE; VERTIGO; and increased intracranial pressure.Bleeding Time: Duration of blood flow after skin puncture. This test is used as a measure of capillary and platelet function.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Fibrin Fibrinogen Degradation Products: Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis.Clinical Nursing Research: Research carried out by nurses in the clinical setting and designed to provide information that will help improve patient care. Other professional staff may also participate in the research.Thrombolytic Therapy: Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.Protein S Deficiency: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)Platelet Aggregation: The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.Drug-Eluting Stents: Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.National Institute of Allergy and Infectious Diseases (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. It was established in 1948.Mesenteric Veins: Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein.Subclavian Vein: The continuation of the axillary vein which follows the subclavian artery and then joins the internal jugular vein to form the brachiocephalic vein.Dental Research: The study of laws, theories, and hypotheses through a systematic examination of pertinent facts and their interpretation in the field of dentistry. (From Jablonski, Illustrated Dictionary of Dentistry, 1982, p674)Prothrombin: A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.Popliteal Vein: The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.Hemorrhage: Bleeding or escape of blood from a vessel.Venous Thromboembolism: Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Community-Based Participatory Research: Collaborative process of research involving researchers and community representatives.Jugular Veins: Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.Behavioral Research: Research that involves the application of the behavioral and social sciences to the study of the actions or reactions of persons or animals in response to external or internal stimuli. (from American Heritage Dictionary, 4th ed)Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Antibodies, Antiphospholipid: Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; related autoimmune diseases, some non-autoimmune diseases, and also in healthy individuals.Qualitative Research: Any type of research that employs nonnumeric information to explore individual or group characteristics, producing findings not arrived at by statistical procedures or other quantitative means. (Qualitative Inquiry: A Dictionary of Terms Thousand Oaks, CA: Sage Publications, 1997)Protein C Deficiency: An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)National Institute of Neurological Disorders and Stroke: Component of the NATIONAL INSTITUTES OF HEALTH. It supports and conducts research, both basic and clinical, on the normal and diseases nervous system. It was established in 1950.Cranial Sinuses: Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.Activated Protein C Resistance: A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.National Institute on Aging (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. Through basic and clinical biomedical research and training, it conducts and supports research into the nature of the aging process and diseases associated with the later stages of life. The Institute was established in 1974.Lupus Coagulation Inhibitor: An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.Platelet Activation: A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.Recurrence: The return of a sign, symptom, or disease after a remission.Thromboplastin: Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serves as a cofactor with factor VIIa to activate factor X in the extrinsic pathway of blood coagulation.Human Experimentation: The use of humans as investigational subjects.Renal Veins: Short thick veins which return blood from the kidneys to the vena cava.Tissue Plasminogen Activator: A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.Splenic Vein: Vein formed by the union (at the hilus of the spleen) of several small veins from the stomach, pancreas, spleen and mesentery.Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)Ultrasonography, Doppler, Duplex: Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.Acute Disease: Disease having a short and relatively severe course.Budd-Chiari Syndrome: A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon.Antithrombin III Deficiency: An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.Fibrinolysis: The natural enzymatic dissolution of FIBRIN.Axillary Vein: The venous trunk of the upper limb; a continuation of the basilar and brachial veins running from the lower border of the teres major muscle to the outer border of the first rib where it becomes the subclavian vein.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Protein C: A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.Mesenteric Vascular Occlusion: Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)Catheterization, Central Venous: Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.Postthrombotic Syndrome: A condition caused by one or more episodes of DEEP VEIN THROMBOSIS, usually the blood clots are lodged in the legs. Clinical features include EDEMA; PAIN; aching; heaviness; and MUSCLE CRAMP in the leg. When severe leg swelling leads to skin breakdown, it is called venous STASIS ULCER.Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Fibrin: A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.Cooperative Behavior: The interaction of two or more persons or organizations directed toward a common goal which is mutually beneficial. An act or instance of working or acting together for a common purpose or benefit, i.e., joint action. (From Random House Dictionary Unabridged, 2d ed)Fibrinogen: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Vena Cava Filters: Mechanical devices inserted in the inferior vena cava that prevent the migration of blood clots from deep venous thrombosis of the leg.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Ticlopidine: An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.Postphlebitic Syndrome: A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous VARICOSE VEINS are usually present. Leg pain may occur after long period of standing.Patient Selection: Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.Arteriovenous Shunt, Surgical: Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)Angioplasty, Balloon, Coronary: Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.Antithrombins: Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.Randomized Controlled Trials as Topic: Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.Sirolimus: A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.Partial Thromboplastin Time: The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.History, 21st Century: Time period from 2001 through 2100 of the common era.Blood Coagulation Tests: Laboratory tests for evaluating the individual's clotting mechanism.Informed Consent: Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.Catheters, Indwelling: Catheters designed to be left within an organ or passage for an extended period of time.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Coronary Restenosis: Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Registries: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.Antibodies, Anticardiolipin: Antiphospholipid antibodies found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. The antibodies are detected by solid-phase IMMUNOASSAY employing the purified phospholipid antigen CARDIOLIPIN.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Research Report: Detailed account or statement or formal record of data resulting from empirical inquiry.Empirical Research: The study, based on direct observation, use of statistical records, interviews, or experimental methods, of actual practices or the actual impact of practices or policies.Data Collection: Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.Societies, Medical: Societies whose membership is limited to physicians.Thrombocytopenia: A subnormal level of BLOOD PLATELETS.Catheterization, Peripheral: Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Stockings, Compression: Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.Thrombocythemia, Essential: A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.Blood Coagulation Factors: Endogenous substances, usually proteins, that are involved in the blood coagulation process.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Veins: The vessels carrying blood away from the capillary beds.Blood Coagulation Disorders: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.Enoxaparin: Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)National Institute of Diabetes and Digestive and Kidney Diseases (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports basic and applied research for a national program in diabetes, endocrinology, and metabolic diseases; digestive diseases and nutrition; and kidney, urologic, and hematologic diseases. It was established in 1948.Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.Universities: Educational institutions providing facilities for teaching and research and authorized to grant academic degrees.Vascular Patency: The degree to which BLOOD VESSELS are not blocked or obstructed.Information Dissemination: The circulation or wide dispersal of information.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Infant, Newborn: An infant during the first month after birth.National Institute of Environmental Health Sciences (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports basic and applied research to reduce the burden of human illness and dysfunction from environmental causes by, defining how environmental exposures, genetic susceptibility, and age interact to affect an individual's health. It was established in 1969.National Institute of Child Health and Human Development (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It was initially established to investigate the broad aspects of human development as a means of understanding developmental disabilities, including mental retardation, and the events that occur during pregnancy. It now conducts and supports research on all stages of human development. It was established in 1962.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Embryo Research: Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus during the prenatal stage of development that is characterized by rapid morphological changes and the differentiation of basic structures. In humans, this includes the period from the time of fertilization to the end of the eighth week after fertilization.Multicenter Studies as Topic: Works about controlled studies which are planned and carried out by several cooperating institutions to assess certain variables and outcomes in specific patient populations, for example, a multicenter study of congenital anomalies in children.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Bandages: Material used for wrapping or binding any part of the body.Superior Sagittal Sinus: The long large endothelium-lined venous channel on the top outer surface of the brain. It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. Near the lower back of the CRANIUM, the superior sagittal sinus deviates to one side (usually the right) and continues on as one of the TRANSVERSE SINUSES.Protein S: The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.Interdisciplinary Communication: Communication, in the sense of cross-fertilization of ideas, involving two or more academic disciplines (such as the disciplines that comprise the cross-disciplinary field of bioethics, including the health and biological sciences, the humanities, and the social sciences and law). Also includes problems in communication stemming from differences in patterns of language usage in different academic or medical disciplines.Practice Guidelines as Topic: Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.Plethysmography, Impedance: Recording changes in electrical impedance between electrodes placed on opposite sides of a part of the body, as a measure of volume changes in the path of the current. (Stedman, 25th ed)Public Health: Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.beta 2-Glycoprotein I: A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.Science: The study of natural phenomena by observation, measurement, and experimentation.National Institute on Drug Abuse (U.S.): Component of the NATIONAL INSTITUTES OF HEALTH. It supports a comprehensive research portfolio that focuses on the biological, social, behavioral and neuroscientific bases of drug abuse on the body and brain as well as its causes, prevention, and treatment. NIDA, NIAAA, and NIMH were created as coequal institutes within the Alcohol, Drug Abuse and Mental Health Administration in 1974. It was established within the NATIONAL INSTITUTES OF HEALTH in 1992.United States Agency for Healthcare Research and Quality: An agency of the PUBLIC HEALTH SERVICE established in 1990 to "provide indexing, abstracting, translating, publishing, and other services leading to a more effective and timely dissemination of information on research, demonstration projects, and evaluations with respect to health care to public and private entities and individuals engaged in the improvement of health care delivery..." It supersedes the National Center for Health Services Research. The United States Agency for Health Care Policy and Research was renamed Agency for Healthcare Research and Quality (AHRQ) under the Healthcare Research and Quality Act of 1999.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.Angiography: Radiography of blood vessels after injection of a contrast medium.Platelet Count: The number of PLATELETS per unit volume in a sample of venous BLOOD.Intermittent Pneumatic Compression Devices: Instruments that generate intermittent forces, uniformed or graduated, to facilitate the emptying of VEINS. These devices are used to reduce limb EDEMA and prevent venous THROMBOEMBOLISM, such as deep vein thrombosis in the legs.Thrombin: An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.Biological Specimen Banks: Facilities that collect, store, and distribute tissues, e.g., cell lines, microorganisms, blood, sperm, milk, breast tissue, for use by others. Other uses may include transplantation and comparison of diseased tissues in the identification of cancer.
He serves on the board of trustees of the Thrombosis Research Institute. He is an honorary fellow of Merton College, Oxford and ... "Management & Governance". Thrombosis Research Institute. Retrieved 4 August 2017. "Guy Weston: Honorary Fellow". Merton College ...
Kakkar is Chair of UCLPartners, the Academic Health Science Partnership, Director of the Thrombosis Research Institute, London ... Thrombosis Research Institute Archived February 23, 2010, at the Wayback Machine. http://www.alleyns.org.uk/school.aspx?sid=2 " ... He has research interests in the prevention and treatment of venous thromboembolic disease and cancer-associated thrombosis and ... International Society on Thrombosis and Haemostasis 1997 and the James IV Association of Surgeons Fellow 2006. He is a ...
Among his awards were the Perkin Medal in 1950 and the Industrial Research Institute (IRI) Medal in 1953. The E. V. Murphree ... He died on October 29, 1962 at Overlook Hospital in Summit, New Jersey of coronary thrombosis. He was inducted into the ... Led Esso Research Company. Chemist Helped Establish the Manhattan District Project. Held 39 Patents". New York Times. October ... school for a year he spent several years at the Massachusetts Institute of Technology as a Staff Assistant and Research ...
... and the Robarts Research Institute, one of Canada's leading medical research organizations. He is a recognized expert in stroke ... Recently, he has received the Research Excellence Award from the Canadian Society for Atherosclerosis, Thrombosis and Vascular ... Clinical Pharmacology training at the Cardiovascular Research Institute of the University of California at San Francisco. M.B.A ... Spence is the director of the Stroke Prevention & Atherosclerosis Research Centre (SPARC) located at the Robarts Research ...
"Director profile". Central Drug Research Institute. 2017-11-24. Retrieved 2017-11-24. "Dr. Madhu Dixit Adjunct Research ... Known for her studies on cardiovascular pathologies such as thrombosis, she is also an adjunct professor at Carleton University ... pharmacologist and the director of the Central Drug Research Institute of the Council of Scientific and Industrial Research. ... "Natural Products Research in CDRI - Dr Madhu Dikshit, Director, CSIR-CDRI talks" (YouTube video). CSIR-CDRI India. February 25 ...
In 1935, Ranke joined the Aviation Medical Research Institute of the Military Medical Academy in Berlin, where Hubertus ... Ranke died in 1959 unexpectedly of an arterial thrombosis in his sleep. Rudolf Vierhaus (Hrsg.): Deutsche biographische ... The drug was brought to the attention of Ranke, at the time a military doctor and director of the Institute for General and ... His research interests were sensory and nutritional physiology and physiology of metabolism. Ranke was author of many ...
... a personal friend and the secretary and manager of the Kaiser Wilhelm Institute. Warburg pursued his research until the age of ... This was complicated by deep vein thrombosis. He died in 1970 from pulmonary embolism and was buried in a Christian cemetery. ... In 1918, Warburg was appointed professor at the Kaiser Wilhelm Institute for Biology in Berlin-Dahlem (part of the Kaiser- ... "suffered a broken femur, complicated by deep vein thrombosis, and in 1970, Otto Heinrich Warburg died from a pulmonary embolism ...
... he moved back to Berlin and conducted research at the institute at the Ziegelstrasse. In 1890, Schimmelbusch invented a mask ... During his time at Halle, he assisted Eberth with his work on thrombosis, and the pair published a number of papers together. ... and praised his work in the fields of thrombosis and aseptic techniques. Die Blutplättchen und die Blutgerinnung. Berlin: Druck ...
He moved to the University of Oslo in 1963, as professor and head of the University of Oslo Institute for Thrombosis Research ... Olav, one of the founders and honorary member of the European Thrombosis Research Organization, Co-chairman and Chairman of the ... 1984;51:292 Ørstavik, KH; Stormorken, H; Sparr, T (March 1985). "Hemophilia BM in a female". Thrombosis Research. 37 (5): 561- ... Stormorken, H; Gogstad, GO; Brosstad, F (August 1983). "Hereditary α2-antiplasmin deficiency". Thrombosis Research. 31 (4): 647 ...
The Harry Bateman Research Instructorships at the California Institute of Technology are named in his honour. After his death, ... was on his way to New York to receive an award from the Institute of Aeronautical Science when he died of coronary thrombosis. ... In 1917 he took up his permanent position at California Institute of Technology, then still called Throop Polytechnic Institute ... He died on his way to New York in 1946 of Coronary thrombosis. In 1907 Harry Bateman was lecturing at the University of ...
In this area, initial research is concentrated on in vitro and in vivo models of angiogenesis, thrombosis and vascular biology ... Pharmaceutical Research Institute (PRI)- Albany is an independent, not-for-profit research and development institute dedicated ... This segment of research at the Pharmaceutical Research Institute provides key information that will help bridge the gap ... Experimental research at the Pharmaceutical Research Institute focuses on identifying novel therapeutic and diagnostic ...
... mechanism of early graft thrombosis was recognized with a five-year RO1 clinical research grant from the National Institutes of ... His research manuscripts are available on pubmed. Robert Poston attended University of Texas at Austin 1986-1989 where he ... Robert S. Poston is an American cardiac surgeon at University of Arizona Medical Center most noted for his research in robot- ... Griffith's guidance, he developed a clinical and research niche in off-pump Coronary artery bypass surgery and robotic CABG, ...
... president of Princeton University Sidney Weinhouse headed the Fels Research Institute of Temple University and Cancer Research ... Sherry founded the Council on Thrombosis of the American Heart Association, International Council of Osmosis, and the ... The 2015 U.S. News & World Report medical school research ranking places Temple University School of Medicine 55th best in the ... Machteld Elisabeth Sano, a Belgian-trained clinical pathologist known for her research on tissue culture and use of fibrin glue ...
"Chromosome Abnormalities Fact Sheet". National Human Genome Research Institute (NHGRI). Retrieved 14 May 2017. Leveno 2013, p. ... diabetes Hyperemesis gravidarum Pelvic girdle pain HELLP syndrome Acute fatty liver of pregnancy Deep vein thrombosis Pregnancy ... delivery Uterine rupture Hysterectomy after delivery Postpartum infection Postpartum depression Septic pelvic thrombosis ...
Shaun Jackson - Thrombosis Group Dr Mary Kavurma - Vascular Complications Group A/Prof. Martin Ng - Translational and ... The Heart Research Institute (HRI) is a not-for-profit research facility, originally based in Camperdown, New South Wales, ... the Institute has become a research and research training facility, in particular in investigating the disease atherosclerosis ... Heart Research Institute. Archived from the original on 30 July 2013. Official website. ...
Thrombosis and Vascular Biology Cardiovascular Research Institute homepage Cardiovascular Revascularization Medicine homepage ... His current research interests include brachytherapy for restenosis prevention bioabsorbable/ biodegradable stents, HDL therapy ... Cardiovascular Revascularization Medicine homepage Cardiovascular Research Technologies homepage Cardiovascular Research ...
Malcolm McKibbin - Head, Northern Ireland Civil Service Ajay Kakkar, Baron Kakkar - Director, Thrombosis Research Institute ( ... Members of the Honours Committee-which comprises a main committee and nine subcommittees in speciality areas-research and vet ... Institute for Government Sir Robert Rogers, Baron Lisvane KCB - former Clerk of the House of Commons Mark Harper MP - ... Senior Research Fellow, Nuffield College Dame Glynis Breakwell DBE DL - Vice Chancellor, University of Bath Julia King, ...
Researchers at the Duke Clinical Research Institute have been accused of withholding clinical data used to evaluate rivaroxaban ... On July 1, 2011, the U.S. Food and Drug Administration (FDA) approved rivaroxaban for prophylaxis of deep vein thrombosis (DVT ... National Institute for Health and Clinical Excellence, July 2012 "Medication Guide--Xarelto" (PDF). U.S. Food and Drug ... In July 2012, the UK´s National Institute for Health and Clinical Excellence recommended rivaroxaban to prevent and treat ...
Thrombosis Research Institute, London, Annual Award for 1993 1990: American Cancer Society Professor of Molecular Biology 1988 ... He received his Ph.D. from the Weizmann Institute of Science in Israel in 1971 and conducted his postdoctoral research in the ... Among his professional activities, he is a member of the Board of Scientific Governors of The Scripps Research Institute. He is ... Fellow of the Jane Coffin Childs Memorial Fund for Medical Research "Salk Institute Faculty Directory". Retrieved 25 November ...
Ottawa Health Research Institute (General Campus), the Children's Hospital of Eastern Ontario Research Institute. The medical ... Criteria for Deep Vein Thrombosis and Pulmonary Embolism, through which many emergency departments stratify possibility of DVT ... Research Institute The Royal Ottawa Health Care Group University of Ottawa Heart Institute University of Ottawa Eye Institute ... Palliative Care University of Ottawa Institute of Mental Health Research University of Ottawa Neuroscience Research Institute ...
Lorand, L (July 2005). "Factor XIII and the clotting of fibrinogen: From basic research to medicine". Journal of Thrombosis and ... Lorand is associated with the Feinberg Cardiovascular Research Institute. He was the co-editor of Proteolytic Enzymes, a volume ... Biochemical and Biophysical Research Communications. 15 (2): 182-187. doi:10.1016/0006-291X(64)90321-3. Retrieved November 16, ...
... and thrombolysis in arterial and venous thrombosis research. Lin's research interest is in cellular dysfunction in arterial and ... He was the principal investigator on a five-year National Institute of Health grant to study hypertension and homocysteinemia ... and was concurrently a research assistant in the Vascular Surgery Research Lab at the Loyola Stritch School of Medicine in ... venous thrombosis as well as experimental model of endovascular therapy. His research expertise also includes clinical outcome ...
SBP Medical Discovery Institute 2015 Society for Free Radical Research (SFRR), Clinical Science Award 2014, 2015 Thomson ... Thrombosis & Haemostasis (ISTH) 1998 International Association Francaise Des Hemophiles Award, "Prix Henri Chaigneau" 1993 Dr. ... Neuroscience and Aging Center at Sanford Burnham Prebys Medical Discovery Institute (SBP) and an Adjunct Professor in the ...
In the summer of 1989 he visited Thrombosis Research Institute, Chelsea, London and worked again with Prof. Kakkar's group. In ... After resigning from this Institute, he worked in the Central Food Technological Research Institute, Mysore for five years ( ... Jayadeva Institute of Cardiology, Indian Institute of Sciences, Bangalore; Sri Chitra Tiruanl Institute For Medical Sciences ... and Post Graduate Institute, Lucknow; Nizam's Institute of Medical Sciences, Hyderabad; Madras Diabetes Research Foundation, ...
... was opened in December 1988 as the Shenyang Research Institute of Thrombosis and Liaoning Province ... In November 2001, research at the hospital was awarded the Gold Prize at the 50th World Exhibition of Innovation, Research and ... The Sujiatun Thrombosis Hospital, officially known as the Liaoning Provincial Thrombosis Treatment Center of Integrated Chinese ... It is a thrombosis treatment centre approved by the State Administration of Traditional Chinese Medicine, a class A Grade three ...
"Twin Research and Human Genetics. 18 (6): 762-771. doi:10.1017/thg.2015.83. ISSN 1832-4274. PMID 26678054.. ... "National Institute of Diabetes and Digestive and Kidney Diseases. June 2014. Archived from the original on 6 March 2016. ... Thrombosis and Vascular Biology, Council on Cardiovascular Disease in the, Young.; American Diabetes, Association. (August 2012 ... "Progress in Lipid Research. 48 (1): 44-51. doi:10.1016/j.plipres.2008.10.002. PMC 2654180. PMID 19032965.. ...
Thrombosis Research Institute staff may join the Royal Brompton Campus Library.. You will need to complete a registration form ... Thrombosis Research Institute staff. Total items. Number of weeks. Including 24 hour loans. ... EnterpriseLearn how we support entrepreneurship and help find research-driven solutions to industry challenges ... Imperials impactRead case studies about how Imperial research has made a difference ...
The Heart Research Institute has 12 groups conducting research into heart disease, atherosclerosis, stroke prevention and ... Clinical Research Haematology Research Heart Rhythm and Stroke Prevention High Blood Pressure Thrombosis Vascular Complications ... Copyright 2018 Heart Research Institute - Registered Charity in Australia ABN 41 003 209 952 ... Our research projects. Role of PACAP in the regulation of arterial blood pressure. PACAP is a polypeptide that is present ...
The Heart Research Institute has 12 groups conducting research into heart disease, atherosclerosis, stroke prevention and ... Clinical Research Haematology Research Heart Rhythm and Stroke Prevention High Blood Pressure Thrombosis Vascular Complications ... Copyright 2018 Heart Research Institute - Registered Charity in Australia ABN 41 003 209 952 ... The main objective of our research program is to broaden our understanding of the cellular and molecular mechanisms involved in ...
... Monday, ... Professor of Surgery at University College London and Director of the Thrombosis Research Institute (TRI), UK. ... World Thrombosis Day. Know Thrombosis. Available at: http://www.worldthrombosisday.org/issue/thrombosis/. [Last accessed: 10 ... A blood clot in an artery in the brain leads to a stroke; 92% of fatal strokes are caused by thrombosis.[5] Stroke is a major ...
Murdoch Childrens Research Institute. Royal Childrens Hospital. Flemington Road, Parkville. Victoria 3052 Australia. ABN 21 ... Research and practice in thrombosis and haemostasis 3 (1) : 99 - 108(2019) PubMed ... Education needs of nurses in thrombosis and hemostasis: An international, mixed-methods study. ...
Murdoch Childrens Research Institute. Royal Childrens Hospital. Flemington Road, Parkville. Victoria 3052 Australia. ABN 21 ... Clinical Research Development Office (CRDO)*CRDO Workshops*Core Workshops: Practical skills in research including Good Clinical ... Monagle P. Diagnosis and management of deep venous thrombosis and pulmonary embolism in neonates and children. Seminars in ...
Thrombosis Research Institute (TRI) Launches Innovative Risk Calculator for Predicting Stroke, Major Bleeding and Mortality in ... Source: Thrombosis Research Institute (TRI). Keywords: Computer Software Computer/Electronics Health Care/Hospital Medical ... Thrombosis Research Institute (TRI) Launches Innovative Risk Calculator for Predicting Stroke, Major Bleeding and Mortality in ... Photo - https://mma.prnewswire.com/media/1033769/Thrombosis_Research_Institute_Infographic.jpg ...
The Thrombosis Research Institute is dedicated to bringing new solutions to patients for the detection, prevention and ... Thrombosis Research Institute. Emmanuel Kaye Building. 1b Manresa Road. Chelsea. London. SW3 6LR ... If youd like to discuss the possibilities of building your career with the Thrombosis Research Institute, please contact ... CYTE is a dynamic new clinical research organisation operated by TRI, extending our in house resources and global research site ...
Center for Injury Research and Prevention, Center for Child Injury Prevention Studies, Center for Autism Research, PennCHOP ... by Research Communications Division of Cardiology, University of Pennsylvania, Childrens Hospital of Philadelphia, Division of ... Congress of the International Society of Thrombosis and Haemostasis, Penn Medicine, Sriram Krishnaswamy, division of Hematology ...
Thrombosis Research Institute. Emmanuel Kaye Building. 1b Manresa Road. Chelsea. London. SW3 6LR ... Thrombosis News. Click through to read our pick of some of the recent news stories on thrombosis from around the web. We update ...
Thrombosis Research Institute. London. About Us The single biggest killer in Britain today is cardiovascular disease. It ... About Us Alzheimer s Research UK is the UK s leading dementia research charity dedicated...Read more » ... The Northern Counties Kidney Research Fund (NCKRF) was established in 1972 to support kidney rese...Read more » ... Staying well until a cure is found..... Diabetes Research & Wellness Foundation (DRWF) ai...Read more » ...
Thrombosis Research Institute,. India Location: India - Primary collection method: not provided. Minimum submission review ... Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you ...
HRIs Thrombosis and Haematology Research Groups did their part to raise awareness of thrombosis - a leading factor in heart ... To celebrate World Thrombosis Day, HRIs Thrombosis and Haematology Research Groups did their part to raise awareness of ... The Heart Research Institute (UK) is a registered company limited by guarantee No. 05935975 (England and Wales).. The Heart ... Every donation to the Heart Research Institute is an investment into the lives of millions.. Help us to make a long-lasting ...
Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, 92037, CA, USA. *Wolfram Ruf ... Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center, Mainz, 55131, Germany. *Wolfram Ruf ... Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, L8S 4K1, ON, Canada. *Alberto Caminero ... was granted a Farncombe Fellowship Award and Campbell Research Award. M.M. was supported by a CCFA Research Fellowship Award ( ...
This project will study blood cell adhesion and thrombus formation in microfluidic devices to assess for persisting thrombotic tendency in patients with a history of venous clots, who have completed treatment.
Clinical trial for Venous Thrombosis , Pulmonary Embolism , Venous Thromboembolism , Hokusai Study in Pediatric Patients With ... FSBI of Science Kirov Scientific and Research Institute of Hematology and Blood Transfusion, FMBA. Kirov, Russian Federation ... Indiana Hemophilia and Thrombosis Center. Indianapolis, IN United States. Connect » University of Louisville. Louisville, KY ... Brief Description Eligibility Contact Research Team Receive Emails About New Clinical Trials!. Sign up for our FREE service to ...
Heart & Vascular Outcomes Research Institute. Beverly, Massachusetts, United States. 42. NCT03388775. Recruiting. New. Real ... Upper Limb Thrombosis Associated With Midline Catheter. *Venous Thrombosis Deep (Limbs). *Device: application in midline ... Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial). *Deep Vein Thrombosis ... Age-adjusted D-dimer Cutoff Levels to Rule Out Deep Vein Thrombosis: a Prospective Outcome Study. *Deep Vein Thrombosis ...
Blood Research Institute, Versiti. Milwaukee, WI. Myeloproliferative Neoplasms and Thrombosis. 1:05 p.m. - 2:05 p.m. ... Seattle Childrens Research Institute. Seattle, WA. Functional Determination of All Possible Disease-Associated Variants in a ... Vincents Institute of Medical Research. Fitzroy, Australia. Key Roles of Hoxa1 in Myelodysplastic Syndromes ... Levine L. Cancer Institute. Charlotte, NC. Speakers:. Mehmet K. Samur, PhD. Dana Farber Cancer Institute. Boston, MA. Molecular ...
Variants from Hubei Clinical and Research Center of Thrombosis and Hemostasis Institute of Hematology,. Union Hospital Location ... Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you ...
National Institute for Health Research Journals Library - PDF. Medical. *Thrombosis - Genetic Alliance ... Medical Care Research Unit, University of Sheffield, UK.. Abstract. OBJECTIVES: To estimate the diagnostic accuracy of non- ... Recommendations for research include the evaluation of the costs and outcomes of using the optimal diagnostic algorithms in ... Measurement of the clinical and cost-effectiveness of non-invasive diagnostic testing strategies for deep vein thrombosis.. ...
Keywords provided by Thrombosis Research Institute: Atrial fibrillation. Anticoagulation. Stroke. Stroke prevention. Health ... To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For ... To learn more about this study, you or your doctor may contact the study research staff using the contact information provided ...
Thrombosis Research Institute. *Bayer. *University of Birmingham. *(and 4 more...). Other / Industry. *Observational Model: ... Alabama Clinical Research Institute, Inc. (ACRI). Alexander City, Alabama, United States. *Alabama Clinical Therapeutics, LLC. ... Ironwood Cancer and Research Center. Chandler, Arizona, United States. *21st Century Oncology. Scottsdale, Arizona, United ... Uni of Arkansas For Medical Sciences; Arkansas Cancer Research Center. Little Rock, Arkansas, United States ...
3 Population Health Research Institute, Hamilton, Canada. *4 Hamilton Health Sciences, Hamilton, Canada ... Deep vein thrombosis: update on diagnosis and management. Paul C Kruger, John W Eikelboom, James D Douketis and Graeme J Hankey ... Diagnosis of deep vein thrombosis (DVT) requires a multifaceted approach that includes clinical assessment, evaluation of pre‐ ...
Francis Crick Institute staff. Medical Research Council (MRC) Staff. Thrombosis Research Institute staff. Staff and students of ... Research Grant information (researchers submitting publications to Symplectic or applying for funding to pay open access fees) ... to facilitate the deposit of publications as required by the open access policies of Imperial College London and research ... EnterpriseLearn how we support entrepreneurship and help find research-driven solutions to industry challenges ...
The TRI is a charitable foundation and multi-disciplinary research institute dedicated to the study of thrombosis and related ... led by an international steering committee under the auspices of the Thrombosis Research Institute (TRI), London, UK. To date, ... TRIs mission is to provide excellence in thrombosis research and education, to develop new strategies to prevent and treat ... Ninety-two per cent of fatal strokes are caused by thrombosis.[9] People with AF also are at high risk for heart failure, ...
  • The latest issue of our series MARROW, which presents original research, reviews, perspectives, and commentaries on topics in basic, translational, and clinical and biology and medicine. (nyas.org)
  • Dr. Lowenstein's research is focused on vascular biology. (rochester.edu)
  • Regulatory non-coding RNAs and RNA-binding proteins (RBPs) are important research areas in gene regulation and RNA biology. (rochester.edu)
  • He has research interests in the prevention and treatment of venous thromboembolic disease and cancer-associated thrombosis and, in particular, the role of antithrombotic therapy in prolonging survival in cancer and the role of coagulation serine proteases in tumour biology. (wikipedia.org)
  • The research, which was led by Yanming Wang, a Penn State University associate professor of biochemistry and molecular biology, and Denisa Wagner, senior author with decades of research on thrombosis at the Boston Children's Hospital and the Harvard University Medical School, will be published in in the Online Early Edition of the journal Proceedings of the National Academy of Sciences during the week ending 10 May 2013. (redorbit.com)
  • Measurement of the clinical and cost-effectiveness of non-invasive diagnostic testing strategies for deep vein thrombosis. (nih.gov)
  • A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein. (redorbit.com)
  • Nigel Mackman, Ph.D. The Scripps Research Institute La Jolla. (slideserve.com)
  • We are collaborating with our colleagues in radiology at UC San Diego Health as well as basic researchers at The Scripps Research Institute to investigate molecular aspects of hemophilic joint disease. (ucsd.edu)
  • I'm going to show you the best way to visualize platelets," says Professor Zaverio Ruggeri, giving an impromptu lesson in blood clotting last month in a darkened laboratory in the Molecular and Experimental Medicine (MEM) building at The Scripps Research Institute (TSRI). (scripps.edu)
  • In contrast, patients with thrombosis were found to have significantly higher mean levels of factor VIII, total cholesterol, triglycerides, VLDL cholesterol, and apolipoproteins B-100, C-II, and C-III than those without thrombosis. (bmj.com)
  • 2018 Association for Research in Vision and Opthalmology (ARVO) Annual Meeting, Honolulu, HI, April 29-May 3, 2018. (afar.org)
  • National Institute on Aging (NIA) U13 "Bench-to-Bedside" conference series, Bethesda, MD. March 11-12, 2019. (afar.org)
  • Montreal, Feb. 22, 2017 - A team of researchers from the Research Institute of the McGill University Health Center (RI-MUHC) found that elevations in a unusual form of cholesterol, called Lipoprotein(a) or Lp(a), as responsible for 1 in 14 heart attacks and 1 in 7 cases of aortic valve disease. (eurekalert.org)
  • Thrombosis occurs when platelets and inflammatory cells in the circulating blood come into contact with the thrombogenic necrotic core. (medscape.com)
  • In this issue of Blood , Verhoef et al provide evidence that platelets contain polyphosphate polymers of sufficient size to promote activation of factor XII (FXII), thereby addressing a long-standing enigma as to the potential contribution of platelet polyphosphate to thrombosis. (bloodjournal.org)
  • Platelets have two major functions: hemostastis/thrombosis and an immune regulatory function. (rochester.edu)
  • At the cellular level ( Figure 1 ), thrombosis is initiated by platelets tethering to subendothelial von Willebrand factor (vWF) via the glycoproteinIb (GPIb) [ 2 , 3 ]. (omicsonline.org)
  • But, Watson said, research suggests that HDL function can go awry when its environment is not ideal -- such as when a person is obese or has diabetes or other health conditions causing chronic inflammation in the blood vessels. (hon.ch)
  • Atherosclerotic plaque rupture with thrombosis is the pathologic mechanism responsible for the majority of acute myocardial infarctions (AMI) and sudden coronary death (SCD). (medscape.com)
  • Research in the Small Lab is focused on understanding the molecular mechanisms that control how a cell responds to its surroundings during development or following tissue injury. (rochester.edu)
  • In the search for mechanisms linking complement activation and thrombosis, we found that exuberant complement activation in response to Stx generated an increased amount of C3a that caused further endothelial P-selectin expression, thrombomodulin (TM) loss, and thrombus formation. (jimmunol.org)
  • Other research in the lab examines the epidemiology and unique mechanisms of thrombosis in patients with hemoglobin disorders. (hopkinsmedicine.org)
  • El Khoudary recently received funding from the U.S. National Institute on Aging to expand on this research. (hon.ch)
  • Our mission is to design, conduct and facilitate innovative research that translates into high-quality health care and improved health outcomes for oncology patients with cancer-related symptoms and comorbidities. (mdanderson.org)
  • She was on the organizing committee for ISTH-Boston, overseeing clinical thrombosis programming, and she developed specific early career programming at that ISTH Congress for the first time. (isth.org)