Dronabinol: A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.Pharmacology, Clinical: The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.Marijuana Smoking: Inhaling and exhaling the smoke from CANNABIS.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Cannabis: The plant genus in the Cannabaceae plant family, Urticales order, Hamamelidae subclass. The flowering tops are called many slang terms including pot, marijuana, hashish, bhang, and ganja. The stem is an important source of hemp fiber.Marijuana Abuse: The excessive use of marijuana with associated psychological symptoms and impairment in social or occupational functioning.Receptor, Cannabinoid, CB1: A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Replica Techniques: Methods of preparing tissue specimens for visualization using an electron microscope, usually a scanning electron microscope. The methods involve the creation of exact copies of the specimens by making a mold or cast (i.e., replica) of the specimen.MedlinePlus: NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.Freeze Fracturing: Preparation for electron microscopy of minute replicas of exposed surfaces of the cell which have been ruptured in the frozen state. The specimen is frozen, then cleaved under high vacuum at the same temperature. The exposed surface is shadowed with carbon and platinum and coated with carbon to obtain a carbon replica.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.Consumer Health Information: Information intended for potential users of medical and healthcare services. There is an emphasis on self-care and preventive approaches as well as information for community-wide dissemination and use.North CarolinaAutistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)Asperger Syndrome: A disorder beginning in childhood whose essential features are persistent impairment in reciprocal social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities. These symptoms may limit or impair everyday functioning. (From DSM-5)Nonverbal Communication: Transmission of emotions, ideas, and attitudes between individuals in ways other than the spoken language.Child Development Disorders, Pervasive: Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.United StatesAcademic Medical Centers: Medical complexes consisting of medical school, hospitals, clinics, libraries, administrative facilities, etc.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Lymph Nodes: They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.Database Management Systems: Software designed to store, manipulate, manage, and control data for specific uses.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Information Storage and Retrieval: Organized activities related to the storage, location, search, and retrieval of information.Breast: In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.Breast Neoplasms: Tumors or cancer of the human BREAST.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Carcinoma, Ductal, Breast: An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.Sympathetic Nervous System: The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.Receptors, Estrogen: Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.Science: The study of natural phenomena by observation, measurement, and experimentation.Cyanamide: A cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.Earth (Planet): Planet that is the third in order from the sun. It is one of the four inner or terrestrial planets of the SOLAR SYSTEM.Evolution, Chemical: Chemical and physical transformation of the biogenic elements from their nucleosynthesis in stars to their incorporation and subsequent modification in planetary bodies and terrestrial biochemistry. It includes the mechanism of incorporation of biogenic elements into complex molecules and molecular systems, leading up to the origin of life.Nobel PrizeEvolution, Planetary: Creation and development of bodies within solar systems, includes study of early planetary geology.Biogenesis: The origin of life. It includes studies of the potential basis for life in organic compounds but excludes studies of the development of altered forms of life through mutation and natural selection, which is BIOLOGICAL EVOLUTION.History, 20th Century: Time period from 1901 through 2000 of the common era.Lipopeptides: Compounds consisting of a short peptide chain conjugated with an acyl chain.Face: The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.Educational Measurement: The assessing of academic or educational achievement. It includes all aspects of testing and test construction.Hydroxyeicosatetraenoic Acids: Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.Schools, Veterinary: Educational institutions for individuals specializing in the field of veterinary medicine.Attention: Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.Competency-Based Education: Educational programs designed to ensure that students attain prespecified levels of competence in a given field or training activity. Emphasis is on achievement or specified objectives.Egypt: A country in northern Africa, bordering the Mediterranean Sea, between Libya and the Gaza Strip, and the Red Sea north of Sudan, and includes the Asian Sinai Peninsula Its capital is Cairo.Leadership: The function of directing or controlling the actions or attitudes of an individual or group with more or less willing acquiescence of the followers.Physicians, Women: Women licensed to practice medicine.Agonistic Behavior: Any behavior associated with conflict between two individuals.Territoriality: Behavior in defense of an area against another individual or individuals primarily of the same species.2-Chloroadenosine: 2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system.Lobbying: A process whereby representatives of a particular interest group attempt to influence governmental decision makers to accept the policy desires of the lobbying organization.
Self-replicating machines[edit]. Smart computers or robots would be able to produce copies of themselves. They would be self- ... replicating machines. A growing population of intelligent robots could conceivably outcompete inferior humans in job markets, ... with some claiming that intelligence is too complex to be completely replicated in the near term. However, a small number of ...
In distributed computing, a conflict-free replicated data type (CRDT) is a data structure which can be replicated across ... State-based CRDTs are called convergent replicated data types, or CvRDTs. In contrast to CmRDTs, CvRDTs send their full local ... Shapiro, Marc; Preguiça, Nuno; Baquero, Carlos; Zawirski, Marek (2011), Conflict-Free Replicated Data Types (PDF), Lecture ... Operation-based CRDTs are also called commutative replicated data types, or CmRDTs. CmRDT replicas propagate state by ...
"A Study of a Retroviral Replicating Vector Administered to Subjects With Recurrent Malignant Glioma". Clinical Trials.gov. July ... reported in 2001 the first successful example of applying the use of retroviral replicating vectors towards transducing cell ...
... but the spare space is automatically configured in order to take over the functionality of the dead cell and to replicate it. ... Self-replicating Loops (>>>) Turing Artificial Neural Networks (>>>) Von Neumann's Universal Constructor (>>>) Wolfram's ...
This system of replicating clays and their metabolic phenotype then evolved into the sulfide rich region of the hotspring ... The RNA world hypothesis describes an early Earth with self-replicating and catalytic RNA but no DNA or proteins. It is ... January 1990). "Self-replicating system". Journal of the American Chemical Society. Washington, D.C.: American Chemical Society ... The lipid world theory postulates that the first self-replicating object was lipid-like. It is known that phospholipids form ...
"Self-replicating system. Tjivikua, T., Ballester, P., Rebek, J., Jr. J. Am. Chem. Soc. 1990, 112:1249". Retrieved 2011-08-05. ... Philip Ball in his book, Designing the Molecular World, argues that Rebek's self replicating molecules share some criteria with ... The self-complementary "recipe" has been incorporated universally in self-replicating systems synthesized in other research ... self-replicating molecules. In July 1996, he moved his research group to the Scripps Research Institute to become the director ...
Lee, David H.; Granja, Juan R.; Martinez, Jose A.; Severin, Kay; Ghadiri, M. Reza (1996-08-08). "A self-replicating peptide". ...
"Quines (self-replicating programs)". Rijnard van Tonder. "Pentaquine - 5 part multiquine". Lu Wang. "Quine Chameleon#Variants ... "Ask and ye shall receive: Self-replicating program that goes through three generations, Python, Bash, Perl". b.m. (1 February ... The standard terms for these programs in the computability theory and computer science literature are "self-replicating ... Diagonal lemma Fixed point combinator Self-interpreter Self-replicating machine Self-replication Self-relocation Tupper's self- ...
In later years Ozzie broke open the pendant and discovered Quantum fields; replicating the quantum properties; he thus created ...
"Replicating the Voynich Manuscript". UK: Keele. Retrieved June 8, 2016. McKie, Robin (January 25, 2004). "Secret of historic ...
"Reprap: the replicating rapid prototyper: maximizing customizability by breeding the means of production." HANDBOOK OF RESEARCH ... the replicating rapid prototyper. Robotica, 29(1), 177-191. Durach, Christian F.; Kurpjuweit, Stefan; Wagner, Stephan M. (2017- ...
ISBN 0-19-509599-5. Rebeck, Julius (July 1994). "Synthetic Self-Replicating Molecules". Scientific American: 48-55. Ecology, ... could alter the chemical structure of some of these self-replicating molecules (an analogue for mutation) in such ways that ... could either boost or interfere with its ability to react, thus boosting or interfering with its ability to replicate and ...
A replicating, low molecular weight RNA". Virology. 45 (2): 411-28. doi:10.1016/0042-6822(71)90342-4. PMID 5095900.. ... The RNA world is a hypothetical stage in the evolutionary history of life on Earth, in which self-replicating RNA molecules ... Like DNA, RNA can store and replicate genetic information; like protein enzymes, RNA enzymes (ribozymes) can catalyze (start or ... Opinions differ, however, as to whether RNA constituted the first autonomous self-replicating system or was a derivative of a ...
Early academic work on self-replicating programsEdit. The first academic work on the theory of self-replicating computer ... In order to replicate itself, a virus must be permitted to execute code and write to memory. For this reason, many viruses ... A computer virus is a type of malicious software that, when executed, replicates itself by modifying other computer programs ... If two macro viruses simultaneously infect a document, the combination of the two, if also self-replicating, can appear as a " ...
Jones, R., Haufe, P., Sells, E., Iravani, P., Olliver, V., Palmer, C., & Bowyer, A. (2011). Reprap-- the replicating rapid ... and which is capable of replicating itself by printing many of its own (plastic) parts to create more machines. RepRaps have ...
Replicating portfolio Björk, Tomas (2009). Arbitrage theory in continuous time (3rd ed.). Oxford University Press. p. 87. ISBN ...
doi:10.1016/0167-2789(84)90256-2. Hutton, Tim J. (2010). "Codd's self-replicating computer" (PDF). Artificial Life. 16 (2): 99- ... Codd designed a self-replicating computer in the cellular automaton, based on Wang's W-machine. However, the design was so ...
Experiments in Replicating Hohokam Points. 1973. Tebiwa 16(1):10-45. The Obtuse Angle as a Functional Edge. 1973. Tebiwa 16(1): ... Tebiwa 7(1):1-6. A Stoneworker's Approach to Analyzing and Replicating the Lindenmeier Folsom. 1966. Tebiwa 9(1):3-39. Notes on ...
The replicating portfolio. This, in turn, is built on the assumption of a credit-risk-free environment. Post financial crisis ... under the assumptions of funding at the risk free rate and the ability to perfectly replicate derivatives so as to fully hedge ...
Crush Skarl, the Replicating Beast! (分裂獣スカールを砕け!) 08. Counterstrike! Shiva, the Double-Headed Devil Beast (逆襲! 双頭魔獣シバ) 09
A current research area is in using replicated Sarrus linkages to replace them. The "Core team" of the project has included: Dr ... RepRap is short for replicating rapid prototyper. As an open design, all of the designs produced by the project are released ... Simon Hooper, CNN, 2 June 2005 Self Replicating Robots And The Developing World. KnowProSE.com, 5 June 2005 Interview with Vik ... Sells, E., Smith, Z., Bailard, S., Bowyer, A., & Olliver, V. (2009). Reprap: the replicating rapid prototyper: maximizing ...
The protein Ei gives the catalytic support to build the next sequence in the cycle, Ii+1. The self-replicating sequences I form ... While it has an ability to catalyse polymerization of longer sequences, even of its own length, it cannot replicate itself due ... The hypercycle is a cycle of connected, self-replicating macromolecules. In the hypercycle, all molecules are linked such that ... According to current estimations, the maximum length of a replicated chain that can be correctly reproduced and maintained in ...
Any self-replicating mechanism which does not make a perfect copy will experience genetic variation and will create variants of ... Since all robots (at least in modern times) have a fair number of the same features, a self-replicating robot (or possibly a ... Biological viruses can replicate, but only by commandeering the reproductive machinery of cells through a process of infection ... Many authorities say that in the limit, the cost of self-replicating items should approach the cost-per-weight of wood or other ...
... for self-replicating rapid prototyper). As a result, the price of this technology has dropped by two orders of magnitude since ... which is capable of replicating itself by printing many of its own (plastic) parts to create more machines.[65][66] RepRaps ... "Reprap-- the replicating rapid prototyper". Robotica. 29 (1): 177-191. doi:10.1017/s026357471000069x ...
BrdU: used to identify replicating cells. Used to identify tumors as well as in neuroscience research.[11] ...
Replicating portfolios can be set up to replicate such options and guarantees. It may be easier to value the replicating ... arbitrage opportunities are exploited by constructing a replicating portfolio. In practice, replicating portfolios are seldom, ... In mathematical finance, a replicating portfolio for a given asset or series of cash flows is a portfolio of assets with the ... The market price of those two instruments (that is, the cost of buying this simple replicating portfolio) might be $145 - and ...
In Finance a Replicating Strategy of a particular financial instrument is a set of liquid, usually exchange-traded assets with ... Replicating strategies are used by dealers to hedge the risk exposure that arises from writing options. Self financing ...
Pharmacologists have synthesized new drugs designed to take advantage of the potentially beneficial effects of the active substance in marijuana. Smoking marijuana is known to alleviate anxiety through the action of tetrahydrocannabinol (THC), which is a so-called cannabinoid. Danielle Piomelli...
China replicating Neverland Ranch. 10:59 AM PDT 7/10/2009 by Reuters , AP ...
IBM Big Replicate offers replication across supported Hadoop distributions and versions running on supported Hadoop compatible ... Big Replicate unifies Hadoop clusters running on CDH, HDP, IBM, Amazon S3, EMR, MS Azure, OpenStack Swift and Google Cloud ... Big Replicate can help hospitals digitally assemble all data relating to patients in real time cutting down unacceptable ... IBM Big Replicate. Enables active-active data replication between Hadoop clusters and Object stores, including between cross- ...
Welcome to the website of the former Replicating Effective Programs (REP) project, which includes other related resources. This ... These packaged interventions can guide prevention providers in replicating effective risk-reduction programs in their own ...
In this paper we present an empirical Bayes method for analysing replicated microarray data. Data from all the genes in a ... if any replicates for each gene. Traditional methods using means and standard deviations to detect dierential expression are ... replicate set of experiments are combined into estimates of parameters of a prior distribution. These parameter estimates are ... title = {Replicated Microarray Data},. journal = {Statistica Sinica},. year = {2001},. volume = {12},. pages = {31--46}. }. ...
In distributed computing, a conflict-free replicated data type (CRDT) is a data structure which can be replicated across ... State-based CRDTs are called convergent replicated data types, or CvRDTs. In contrast to CmRDTs, CvRDTs send their full local ... Shapiro, Marc; Preguiça, Nuno; Baquero, Carlos; Zawirski, Marek (2011), Conflict-Free Replicated Data Types (PDF), Lecture ... Operation-based CRDTs are also called commutative replicated data types, or CmRDTs. CmRDT replicas propagate state by ...
We at MAKE were excited about replicating history on our desktop and printed out our own copy of the 1.8 million year old ...
The Supreme Court on Monday for the first time backed patents for a self-replicating technology -- Monsantos Roundup Ready ... The Supreme Court on Monday for the first time backed patents for a self-replicating technology - Monsantos Roundup Ready ... especially for products like soybeans that easily self-replicate. A lower court, an appeals court and even the President Barack ... rather than every one involving a self-replicating product. ... Supreme Court Backs Patents on Seeds (Self-Replicating ...
Folded over or backward; folded back upon itself; as, a replicate leaf or petal; a replicate margin of a shell. ...
Go forth and replicate!. To make replication studies more useful, researchers must make more of them, funders must encourage ... No scientist wants to be the first to try to replicate anothers promising study: much better to know what happened when others ... assuming that others will want to replicate their work. We urge funders and publishers to support tools that help researchers ...
I am coming across various problems replicating the ways product variations are displayed in the demo store with new, custom ... In case this helps anyone wanting to duplicate product types, I use the following two modules to replicate each of the types:. ... Bit fiddly, and probably bad practice / plain wrong for many reasons, but it was the only way I found to replicate the nice ... I am coming across various problems replicating the ways product variations are displayed in the demo store with new, custom ...
Replicating Effective Programs (REP) is a CDC-initiated project that supports the translation of evidence-based HIV/AIDS ...
... you arent exactly going to replicate a 1mm circuitous worm hole that way. ... you arent exactly going to replicate a 1mm circuitous worm hole that way. ...
Bootstrap ANOVA can use these replicates to extract system-topic interactions---something not possible without replicates--- ... Randomly partitioning the test document collection allows for multiple tests of a given system and topic (replicates). ...
Ferrie added, "There is no payload in this virus-it simply replicates. However, it wont replicate very well, because it is ... but say the risk level is very low because it does not replicate effectively.. *Share this item with your network: ... but say the risk level is very low because it does not replicate effectively. ...
Researchers at Duke University report theyve replicated autism symptoms in mice using one gene mutation, one of the first so- ... Autism symptoms have been replicated in mice using one gene mutation, one of the first so-called single-gene knockouts that ... But these mouse models of autism replicated only a few specific behavioral traits associated with autism. ... Scientists examining genetic traits or environmental exposures that can contribute to autism have previously replicated ...
VRX496 is an example of a conditionally replicating HIV vector that replicates only in the presence of wild type HIV, and it ... Gene transfer in humans using a conditionally replicating lentiviral vector. Bruce L. Levine, Laurent M. Humeau, Jean Boyer, ... Gene transfer in humans using a conditionally replicating lentiviral vector. Bruce L. Levine, Laurent M. Humeau, Jean Boyer, ... Gene transfer in humans using a conditionally replicating lentiviral vector. Bruce L. Levine, Laurent M. Humeau, Jean Boyer, ...
For example, it is determined whether the set of groups to be replicated to new master site 162 excludes the master group 110 b ... In step 420, it is determined whether the set of groups being replicated on the new master site is a subset of the master ... is a flowchart that illustrates a high level view of a method 200 for replicating groups of database objects onto a new master ... In step 418, it is determined whether any two or more of the master groups being replicated on the new master site have ...
Prior to this, the only way to replicate pieces such as the Thomas Jefferson statue would be to make a copy employing rubber ... Smithsonian employs 3D printing to replicate collections. The Smithsonian Institute intends to digitize its 137 million-piece ...
do-social-science-research-findings-replicate.html - do-social-science-research-findings-replicate.html Do social science ... The markets were highly accurate in predicting which studies would later succeed or fail to replicate. The prediction markets ... The team tried to replicate one main finding from every eligible experimental social science paper published between 2010 and ... Nevertheless, some original authors provided commentaries with potential reasons for failures to replicate. These productive ...
Breast cancer replicates brain development process. University of York. Journal. International Journal of Cancer. Funder. ... What is most exciting is that the mechanism by which Beta One regulates migration appears to replicate what it does in the ...
PARTS OF REPLICATED STORAGE A replicated storage contains several parts. First, there is the replicated storage itself (DBIx:: ... Class::Storage::DBI::Replicated). A replicated storage takes a pool of replicants (DBIx::Class::Storage::DBI::Replicated::Pool ... In this case, we are setting the Replicated storage type using ::DBI::Replicated as the first value. You will only use a ... DBIx::Class::Storage::DBI::Replicated::Balancer::First, DBIx::Class::Storage::DBI::Replicated::Balancer::Random. ...
The team then set out to replicate the experiment using modern equipment. They were able to verify that the reaction did create ... were able to replicate the old experiment using modern technology. The team was also able to show that the reaction could have ... San Diego was able to successfully replicate a mysterious and groundbreaking experiment by the "Father of Pre-biotic Chemistry ... researchers have been regularly delving into Millers past work and replicating his greatest experiment in different ways. In ...
  • Dynamic replication is fundamental to the Black-Scholes model of derivatives pricing, which assumes that derivatives can be replicated by portfolios of other securities, and thus their prices determined. (wikipedia.org)
  • If you want to use replication, you will override this setting so that the replicated storage engine will 'wrap' your underlying storages and present a unified interface to the end programmer. (cpan.org)
  • In particular, although simple artificial self-replicating systems including wooden blocks, magnetic systems, modular robots and synthetic molecular systems have been devised, such kinematic self-replicators are rare compared with examples of theoretical cellular self-replication. (phys.org)
  • If we can find out how the virus evades immune responses and learn more about the signals the virus sees as necessary for replicating within the host cell, then we can figure out how to inhibit them and halt the viral replication," she said. (innovations-report.com)
  • So while the idea of replicating successful initiatives may seem like the epitome of empirical, social-science-driven public policy, replication itself actually has a fairly poor track record. (nationalaffairs.com)
  • A fuller understanding of replication-coupled nucleosome assembly will be needed to explain how epigenetic information is replicated at every cell division. (sciencemag.org)
  • And the journal Social Psychology devoted its most recent issue to replication - and failed to replicate a number of high-profile findings in social psychology. (insidehighered.com)
  • While previously reported nucleic acid-based self-replicating systems rely on pre-synthesis of (short) oligonucleotide sequences, self-replication in the present systems start from units containing only a single nucleobase. (rug.nl)
  • The Replication Crisis began in 2015 when a group of 270 contributing authors undertook what they called the Reproducibility Project and attempted to replicate 100 studies that had been published in three of the top psychology journals: Psychological Science, Journal of Personality and Social Psychology, and Journal of Experimental Psychology. (aier.org)
  • In this report, we examined the ability of ONYX-015 to infect and replicate in s.c. tumors following either ( a ) direct injection into and replication within a distant tumor or ( b ) i.v. administration. (aacrjournals.org)
  • The results demonstrate that ONYX-015 localized and replicated efficiently within tumors following i.v. administration and that viral replication was associated with significant antitumoral efficacy. (aacrjournals.org)
  • A mutant that affects the function of autonomously replicating sequences in yeast. (nih.gov)
  • The government will replicate twin city model of urban development for cities like Halol-Vadodara,Madhapar-Bhuj and Surendranagar-Vadhavan, Modi said at a programme of Gandhinagar Urban Development Authority (GUDA). (indianexpress.com)
  • Official: Other cities hope to replicate Louisville's asthma inhaler study Mayor Greg Fischer said Air Louisville "is a prime example of how these types of things keeps me excited about the future of the city. (courier-journal.com)
  • The markets were highly accurate in predicting which studies would later succeed or fail to replicate. (uibk.ac.at)
  • Though the scale at which studies fail to replicate is shocking, that scientific endeavors come up with false conclusions should not come as a surprise to anyone. (aier.org)
  • If you understand how this search bar works and can replicate the functionality of this with some changes you can bid for this project. (freelancer.com)
  • Autism symptoms have been replicated in mice using one gene mutation, one of the first so-called single-gene knockouts that scientists say puts them another step closer to understanding a genetic link to autism, researchers at Duke University reported. (go.com)
  • This new model, according to researchers, used a known gene mutation associated with autism -- called the SHANK3 gene mutation -- to replicate a wider range of behaviors that include impaired social interaction and repetitive behaviors. (go.com)
  • This trial evaluated the safety of a conditionally replicating HIV-1-derived vector expressing an antisense gene against the HIV envelope. (pnas.org)
  • We believe this is the first time a gene-diet interaction influencing BMI and obesity has been replicated in as many as three independent study populations," said corresponding and senior author Jose Ordovas, PhD, director of the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts. (innovations-report.com)
  • While selected SNPs in replicates of the same treatment (desiccation-selection or lab-adaptation) tended to change frequency in the same direction, suggesting some commonality in the selection response, candidate SNP and gene lists often differed among replicates. (genetics.org)
  • Three of the five desiccation-selection replicates showed significant overlap at the gene and network level. (genetics.org)
  • More recently gene transfer has been attempted with oncolytic, replicating viruses. (clinicaltrials.gov)
  • To overcome these shortcomings of previous gene transfer protocols, Toca 511 has been developed utilizing a Retroviral Replicating Vector (RRV). (clinicaltrials.gov)
  • In a tribute to his old mentor and colleague, a marine chemistry professor at the University of California, San Diego was able to successfully replicate a mysterious and groundbreaking experiment by the "Father of Pre-biotic Chemistry. (redorbit.com)
  • According to a newly published report in the journal Angewandte Chemie , Miller's old student and colleague Jeffrey Bada , along with a team of American researchers, were able to replicate the old experiment using modern technology. (redorbit.com)
  • The team then set out to replicate the experiment using modern equipment. (redorbit.com)
  • Like tribute bands putting their own twist on a classic hit, researchers have been regularly delving into Miller's past work and replicating his greatest experiment in different ways. (redorbit.com)
  • Attempts to replicate an experiment failed more often if there was no author overlap. (insidehighered.com)
  • When sample replicates are limited in a label-free proteomics experiment, selecting differentially regulated proteins with an assignment of statistical significance remains difficult for proteins with a single-peptide hit or a small fold-change. (hindawi.com)
  • This is a multicenter, open-label, ascending-dose trial of the safety and tolerability of increasing doses of Toca 511, a Retroviral Replicating Vector (RRV), administered to subjects with recurrent high grade glioma (rHGG) who have undergone surgery followed by adjuvant radiation therapy and chemotherapy. (clinicaltrials.gov)
  • Biology provides numerous examples of self-replicating machines, but artificially engineering such complex systems remains a formidable challenge. (phys.org)
  • In developing neuromorphic chips to artificially replicate the circuits that mimic brain structure and function, the functions of generation and transmission of spontaneous spikes that mimic nerve impulses (spikes) have not yet been fully utilized. (phys.org)
  • Data from all the genes in a replicate set of experiments are combined into estimates of parameters of a prior distribution. (psu.edu)
  • All five replicates showed enrichment for ovary-expressed genes, suggesting maternal effects on the selected trait. (genetics.org)
  • Overall, while there was overlap in the direction of allele frequency changes and the network and functional categories affected by desiccation selection, replicates showed unique responses at all levels, likely reflecting hitchhiking effects, and highlighting the challenges in identifying candidate genes from these types of experiments when traits are likely to be polygenic. (genetics.org)
  • We used pooled whole-genome sequencing (Pool-Seq) to compare the genetic basis of their selection responses, using a matching set of replicated control lines for characterizing laboratory (lab-)adaptation, as well as the original base population. (genetics.org)
  • A sub-domain of the viral polymerase undergoes large-scale structural reorganization to enable an essential part of the polymerase to enter the nucleus of the infected cell, where the viral genome is replicated. (medicalnewstoday.com)
  • The resulting vectors are self-replicating and have a high copy number. (etis.ee)
  • Big Replicate can help hospitals digitally assemble all data relating to patients in real time cutting down unacceptable downtime. (ibm.com)
  • In distributed computing , a conflict-free replicated data type ( CRDT ) is a data structure which can be replicated across multiple computers in a network , where the replicas can be updated independently and concurrently without coordination between the replicas, and where it is always mathematically possible to resolve inconsistencies which might result. (wikipedia.org)
  • Accordingly, much of distributed computing focuses on the problem of how to prevent concurrent updates to replicated data. (wikipedia.org)
  • Operation-based CRDTs are also called commutative replicated data types , or CmRDTs . (wikipedia.org)
  • State-based CRDTs are called convergent replicated data types , or CvRDTs . (wikipedia.org)
  • Additionally, if you need high data integrity, such as when you are executing a transaction, replicated storage will automatically delegate all database traffic to the master storage. (cpan.org)
  • This module provides a replicated data store that is coordinated using a variation on Lamport's Paxos concensus protocol. (swi-prolog.org)
  • We present the first scalable, geo-replicated storage system that guarantees low latency, offers a rich data model, and provides "stronger" semantics. (usenix.org)
  • Modern Web applications such as Facebook rely on geo-replicated storage, replicating their entire data stores in multiple data centers in order to serve each client quickly from the nearest one. (usenix.org)
  • A replicated database system is a distributed database system in which some data objects are stored redundantly at multiple sites to improve the reliability of the system. (umd.edu)
  • In the present study, we systematically evaluated SNP detection performance of three strategies to utilize the duplicated exome data of 92 subjects, only using the data with higher depth, only using the data with lower depth, and using the merged data from technical replicates. (hindawi.com)
  • These data showed that some cancer cells have decreased fidelity in replicating methylation patterns in some CGIs, and that the decrease could lead to methylation of the entire CGIs. (aacrjournals.org)
  • I am looking for all possible solutions to replicate data from our Oracle production database to Microsoft SQL Server for reporting. (techtarget.com)
  • If you don't want to use triggers, then you will have a delay in replicating your data. (techtarget.com)
  • In this case, you'll have to set up your own routines to replicate the data. (techtarget.com)
  • Distributed systems maintain copies of geo-replicated data sets on multiple machines connected via computer networks. (mun.ca)
  • Replicated Data Types (RDTs) provide encapsulated resolution policies on how to resolve conflicts when replicas on a network/cluster exchange updates. (mun.ca)
  • In biological systems, DNA replicates with the aid of proteins. (phys.org)
  • However, Junghoon Kim, Junwye Lee, Shogo Hamada, Satoshi Murata, and Sung Ha Park of Sungkyunkwan University and Tohoku University have designed a controllable self-replicating system that does not require proteins. (phys.org)
  • You're suggesting we shouldn't look into self-replicating structures because one day far down the road, some evil government agency MIGHT use it to unleash a horde of nanobots which will destroy the world? (slashdot.org)
  • Published in the Jan. 27 issue of Nature , the study reports that even in undetectable patients, HIV is still replicating in the lymphoid tissues-a part of the immune system that's spread among structures like the lymph nodes, tonsils, and spleen. (slate.com)
  • DNA is a self-replicating molecule where its component parts, nucleotides, have specific chemical interactions that allow for the design of self-assembled structures. (phys.org)
  • Here, we show that DNA T-motifs, which self-assemble into ring structures, can be designed to self-replicate through toehold-mediated strand displacement reactions. (phys.org)
  • To document the in vivo interactions occurring between the immune system and HIV replicating cells, we analyzed using in situ hybridization the production of IL-1 beta, IL-6, IL-2, and INF-gamma in eight hyperplastic lymph nodes from HIV-1 infected patients. (jci.org)
  • In Replicating Success, we learn about innovative collaborations between community colleges, government and community organizations for economic development, and the biotechnology industry. (bio-link.org)
  • Here, we investigate this issue in a set of replicated Drosophila melanogaster lines selected for increased desiccation resistance-a classical physiological trait that has been closely linked to Drosophila species distributions. (genetics.org)
  • Replicating Effective Programs (REP) is a CDC-initiated project that supports the translation of evidence-based HIV/AIDS prevention interventions into everyday practice, by working with the original researchers in developing a user-friendly package of materials designed for prevention providers. (cdc.gov)
  • A fully operational process plant replicating industry practice to demonstrate chemical reaction, solids handling, filtration, and CO 2 capture. (surrey.ac.uk)
  • A team of Japanese and Taiwanese paddlers in a dugout canoe on Tuesday successfully replicated a hypothetical human migration between Taiwan and Okinawa about 30,000 years ago. (japantimes.co.jp)
  • Self-organization emerges only through a process of cyclic development with limited evolution/variation within each cycle, a self-replicating development that becomes incrementally tuned for progressively greater self-assembly, self-repair, and self-reorganization, particularly at the lowest component levels. (accelerationwatch.com)
  • It'd be a pretty shitty story that went "Thousands of years ago, a civilisation created a self-replicating machine. (slashdot.org)
  • Rapid prototyping and 3D printing are becoming commonplace, but the development of a self-replicating machine is making it possible for anyone to have their own machine for around the same price as a high-specification mobile telephone. (engineerlive.com)
  • But the concept of a self-replicating machine is now closer to reality than ever before, with one group of researchers, based in the UK's University of Bath, claiming that in May 2008 the first 'child' was produced from a 'parent' machine, and the first 'grandchild' produced by the 'child' machine shortly after the 'child' was assembled (Fig.1). (engineerlive.com)
  • The team tried to replicate one main finding from every eligible experimental social science paper published between 2010 and 2015. (uibk.ac.at)
  • But, as some states and cities are learning, replicating an initiative like the Tennessee Promise isn't an exact science. (insidehighered.com)
  • The government is spending $1.6 million on a project to try to replicate Chinese mothers ' milk, Zhang Xiaohua, an official with the Beijing Science and Technology Commission, said this week. (chinadigitaltimes.net)
  • In the world of science fiction, authors have written about self-replicating machines that reproduce and take over the world. (engineerlive.com)
  • What is most exciting is that the mechanism by which Beta One regulates migration appears to replicate what it does in the central nervous system. (eurekalert.org)
  • In mathematical finance, a replicating portfolio for a given asset or series of cash flows is a portfolio of assets with the same properties (especially cash flows). (wikipedia.org)
  • Given an asset or liability, an offsetting replicating portfolio (a "hedge") is called a static hedge or dynamic hedge, and constructing such a portfolio (by selling or purchasing) is called static hedging or dynamic hedging. (wikipedia.org)
  • The notion of a replicating portfolio is fundamental to rational pricing, which assumes that market prices are arbitrage-free - concretely, arbitrage opportunities are exploited by constructing a replicating portfolio. (wikipedia.org)
  • See explication under Rational pricing #The replicating portfolio. (wikipedia.org)
  • The market price of those two instruments (that is, the cost of buying this simple replicating portfolio) might be $145 - and therefore the value of the cashflows is also taken to be $145 (as opposed to the face value of the total cash flows at the conclusion of the 7 years, which is $162). (wikipedia.org)
  • It should be clear that the advantages of a replicating portfolio approach include: an arbitrary discount rate is not required the term structure of interest rates is automatically taken into account. (wikipedia.org)
  • It may be easier to value the replicating portfolio than to value the underlying feature (options and guarantees). (wikipedia.org)
  • 2015). This suggests that in some cases the success of programmes may be due to unique features such as special teachers, school leaders, peer environments, or other factors that cannot be easily replicated. (voxeu.org)
  • As Tennessee's Promise program expands to include adult students, other community college scholarship programs are figuring out how to replicate its success. (insidehighered.com)
  • Can Government Replicate Success? (nationalaffairs.com)
  • This record does not mean, however, that policymakers should conclude that they cannot ever replicate success and should not try to learn from the achievements of others. (nationalaffairs.com)
  • A lack of due skepticism, and especially a lack of patience to wait for reliable, replicated results before moving ahead with a major new initiative, add up to a large part of the reason for the difficulty policymakers have had in scaling up success. (nationalaffairs.com)
  • Each of the three said Gonzaga's sustained success is unique, and while its manner of doing so isn't the only model, it is certainly one that is difficult to replicate. (spokesman.com)
  • While the Spartans would like to have the same success as Gonzaga, Bankhead said they aren't trying to replicate the Zags' model. (spokesman.com)
  • Having witnessed the success of the USAID-funded IREX project "Village -online", the Ministry of Communications and High Technologies of Azerbaijan decided to replicate it by installing 15 more similar kiosks in remote villages. (usaid.gov)
  • In this regard, DNA is a prime candidate material for constructing self-replicating systems due to its ability to self-assemble through molecular recognition. (phys.org)
  • Linking physically-based self-replicating systems (SRS's) to the emerging biologically inspired computational systems (neural networks, genetic algorithms, evolutionary systems) which are their current predecessors will be another important bottom up method, as first envisioned by John Von Neumann in the 1950's. (accelerationwatch.com)
  • The imperfections in technology and the own biological variability result in non-identical replicated features that are more similar to one another than features from different subjects. (uci.edu)
  • Welcome to the website of the former Replicating Effective Programs (REP) project, which includes other related resources. (cdc.gov)
  • Dr Adrian Bowyer initiated the Reprap (replicating rapid-prototyper) project in 2004, with the aim of developing a rapid prototyping or three-dimensional (3D) printing machine that would be capable of manufacturing the majority of its own components. (engineerlive.com)
  • Although the goal of the project is to create a machine that can replicate itself, the machine's usefulness extends much further. (engineerlive.com)
  • Physical SRS's, like today's primitive self-replicating robots , provide an emerging body for the emerging mind of the coming machine intelligence, a way for it to learn, from the bottom up the myriad lessons of 'common sense' interaction in the physical world (e.g., sensorimotor before instinctual before linguistic learning). (accelerationwatch.com)
  • Here, we analyzed the fidelity in replicating their methylation statuses in cancer cells. (aacrjournals.org)
  • Recently, taking advantage of methylation analysis by sequencing after bisulfite modification (13) , we measured the fidelity in replicating the methylation status of each CpG site in normal cells (14) . (aacrjournals.org)
  • ONYX-015 (dl1520) is an attenuated adenovirus that replicates in and causes selective lysis of cancer cells. (aacrjournals.org)
  • For additional information on economic valuations and replicating portfolios can be found here: The Economics of Insurance Sart, Frédéric (2010). (wikipedia.org)
  • The MPSP rule generates permuted sample pairings from limited analytical replicates and simply requires that a differentially regulated protein can be selected only when it is found significant in designated number of permuted sample pairings. (hindawi.com)
  • This wrapper storage class will delegate method calls to either a master database or one or more replicated databases based on if they are read only (by default sent to the replicants) or write (reserved for the master). (cpan.org)
  • Additionally, the Replicated storage will monitor the health of your replicants and automatically drop them should one exceed configurable parameters. (cpan.org)
  • A replicated storage contains several parts. (cpan.org)