Procedures which temporarily or permanently remedy insufficient cleansing of body fluids by the kidneys.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Extracorporeal ULTRAFILTRATION technique without HEMODIALYSIS for treatment of fluid overload and electrolyte disturbances affecting renal, cardiac, or pulmonary function.
Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
The combination of hemodialysis and hemofiltration either simultaneously or sequentially. Convective transport (hemofiltration) may be better for removal of larger molecular weight substances and diffusive transport (hemodialysis) for smaller molecular weight solutes.
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
Therapeutic use of hormones to alleviate the effects of hormone deficiency.
A disease or state in which death is possible or imminent.
Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.
A subspecialty of internal medicine concerned with the anatomy, physiology, and pathology of the kidney.
Long-term maintenance hemodialysis in the home.
The transference of a kidney from one human or animal to another.
Therapeutic replacement or supplementation of defective or missing enzymes to alleviate the effects of enzyme deficiency (e.g., GLUCOSYLCERAMIDASE replacement for GAUCHER DISEASE).
Devices which can substitute for normally functioning KIDNEYS in removing components from the blood by DIALYSIS that are normally eliminated in the URINE.
Decreased URINE output that is below the normal range. Oliguria can be defined as urine output of less than or equal to 0.5 or 1 ml/kg/hr depending on the age.
Pathological processes of the KIDNEY or its component tissues.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Hospital units providing continuous surveillance and care to acutely ill patients.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
Those hospitals which are extensions of a main hospital and are wholly or partly administered by that hospital.
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
Disturbances in the body's WATER-ELECTROLYTE BALANCE.
Elements of limited time intervals, contributing to particular results or situations.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Health care provided to a critically ill patient during a medical emergency or crisis.
Any materials used in providing care specifically in the hospital.
Advanced and highly specialized care provided to medical or surgical patients whose conditions are life-threatening and require comprehensive care and constant monitoring. It is usually administered in specially equipped units of a health care facility.
Portable peritoneal dialysis using the continuous (24 hours a day, 7 days a week) presence of peritoneal dialysis solution in the peritoneal cavity except for periods of drainage and instillation of fresh solution.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Hospital units in which care is provided the hemodialysis patient. This includes hemodialysis centers in hospitals.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Hospital units providing continuous surveillance and care to acutely ill infants and children. Neonates are excluded since INTENSIVE CARE UNITS, NEONATAL is available.
Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
Artificial organs that are composites of biomaterials and cells. The biomaterial can act as a membrane (container) as in BIOARTIFICIAL LIVER or a scaffold as in bioartificial skin.
Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Application of a life support system that circulates the blood through an oxygenating system, which may consist of a pump, a membrane oxygenator, and a heat exchanger. Examples of its use are to assist victims of smoke inhalation injury, respiratory failure, and cardiac failure.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Solutions prepared for hemodialysis. The composition of the pre-dialysis solution may be varied in order to determine the effect of solvated metabolites on anoxia, malnutrition, acid-base balance, etc. Of principal interest are the effect of the choice of buffers (e.g., acetate or carbonate), the addition of cations (Na+, K+, Ca2+), and addition of carbohydrates (glucose).
KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.
An acronym for Acute Physiology and Chronic Health Evaluation, a scoring system using routinely collected data and providing an accurate, objective description for a broad range of intensive care unit admissions, measuring severity of illness in critically ill patients.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Catheters designed to be left within an organ or passage for an extended period of time.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Absence of urine formation. It is usually associated with complete bilateral ureteral (URETER) obstruction, complete lower urinary tract obstruction, or unilateral ureteral obstruction when a solitary kidney is present.
Solutions prepared for exchange across a semipermeable membrane of solutes below a molecular size determined by the cutoff threshold of the membrane material.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.
A diverse family of extracellular proteins that bind to small hydrophobic molecules. They were originally characterized as transport proteins, however they may have additional roles such as taking part in the formation of macromolecular complexes with other proteins and binding to CELL SURFACE RECEPTORS.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
An enzyme that catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-galactosides including galactose oligosaccharides, galactomannans, and galactolipids.
The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
The balance of fluid in the BODY FLUID COMPARTMENTS; total BODY WATER; BLOOD VOLUME; EXTRACELLULAR SPACE; INTRACELLULAR SPACE, maintained by processes in the body that regulate the intake and excretion of WATER and ELECTROLYTES, particularly SODIUM and POTASSIUM.
Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS.
Parliamentary democracy located between France on the northeast and Portugual on the west and bordered by the Atlantic Ocean and the Mediterranean Sea.
Islands lying between southeastern North America and northern South America, enclosing the Caribbean Sea. They comprise the Greater Antilles (CUBA; DOMINICAN REPUBLIC; HAITI; JAMAICA; and PUERTO RICO), the Lesser Antilles (ANTIGUA AND BARBUDA and the other Leeward Islands, BARBADOS; MARTINIQUE and the other Windward Islands, NETHERLANDS ANTILLES; VIRGIN ISLANDS OF THE UNITED STATES, BRITISH VIRGINI ISLANDS, and the islands north of Venezuela which include TRINIDAD AND TOBAGO), and the BAHAMAS. (From Webster's New Geographical Dictionary, 1988, p1330)
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.
INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
Agents that prevent clotting.
An X-linked inherited metabolic disease caused by a deficiency of lysosomal ALPHA-GALACTOSIDASE A. It is characterized by intralysosomal accumulation of globotriaosylceramide and other GLYCOSPHINGOLIPIDS in blood vessels throughout the body leading to multi-system complications including renal, cardiac, cerebrovascular, and skin disorders.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
Compounds that interact with PROGESTERONE RECEPTORS in target tissues to bring about the effects similar to those of PROGESTERONE. Primary actions of progestins, including natural and synthetic steroids, are on the UTERUS and the MAMMARY GLAND in preparation for and in maintenance of PREGNANCY.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Surgery performed on the heart.
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
The period of confinement of a patient to a hospital or other health facility.
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.
An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
A disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling LIPOMA.
Items used to aid in ending a TOBACCO habit.
Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)
The application of suitable drug dosage forms to the skin for either local or systemic effects.
Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
A group of islands in the southwest Pacific. Its capital is Wellington. It was discovered by the Dutch explorer Abel Tasman in 1642 and circumnavigated by Cook in 1769. Colonized in 1840 by the New Zealand Company, it became a British crown colony in 1840 until 1907 when colonial status was terminated. New Zealand is a partly anglicized form of the original Dutch name Nieuw Zeeland, new sea land, possibly with reference to the Dutch province of Zeeland. (From Webster's New Geographical Dictionary, 1988, p842 & Room, Brewer's Dictionary of Names, 1992, p378)
A pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.
Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
An autosomal recessively inherited glycogen storage disease caused by GLUCAN 1,4-ALPHA-GLUCOSIDASE deficiency. Large amounts of GLYCOGEN accumulate in the LYSOSOMES of skeletal muscle (MUSCLE, SKELETAL); HEART; LIVER; SPINAL CORD; and BRAIN. Three forms have been described: infantile, childhood, and adult. The infantile form is fatal in infancy and presents with hypotonia and a hypertrophic cardiomyopathy (CARDIOMYOPATHY, HYPERTROPHIC). The childhood form usually presents in the second year of life with proximal weakness and respiratory symptoms. The adult form consists of a slowly progressive proximal myopathy. (From Muscle Nerve 1995;3:S61-9; Menkes, Textbook of Child Neurology, 5th ed, pp73-4)
Replacement of the hip joint.
An infant during the first month after birth.
Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.
A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Physiologic period, characterized by endocrine, somatic, and psychic changes with the termination of ovarian function in the female. It may also accompany the normal diminution of sexual activity in the male.
A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Prospective patient listings for appointments or treatments.
The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. These proteins can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumor markers.
Replacement of the knee joint.
Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.
Special hospitals which provide care for ill children.
The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
Works about controlled studies which are planned and carried out by several cooperating institutions to assess certain variables and outcomes in specific patient populations, for example, a multicenter study of congenital anomalies in children.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.

Late referral of end-stage renal failure. (1/652)

We studied all new patients accepted for renal replacement therapy (RRT) in one unit from 1/1/96 to 31/12/97 (n = 198), to establish time from nephrology referral to RRT, evidence of renal disease prior to referral and the adequacy of renal management prior to referral. Sixty four (32.3%, late referral group) required RRT within 12 weeks of referral. Fifty-nine (29.8%) had recognizable signs of chronic renal failure > 26 weeks prior to referral. Patients starting RRT soon after referral were hospitalized for significantly longer on starting RRT (RRT within 12 weeks of referral, median hospitalization 25.0 days (n = 64); RRT > 12 weeks after referral, median 9.7 days (n = 126), (p < 0.001)). Observed survival at 1 year was 68.3% overall, with 1-year survival of the late referral and early referral groups being 60.5% and 72.5%, respectively (p = NS). Hypertension was found in 159 patients (80.3%): 46 (28.9%) were started on antihypertensive medication following referral, while a further 28 (17.6%) were started on additional antihypertensives. Of the diabetic population (n = 78), only 26 (33.3%) were on an angiotensin-converting-enzyme inhibitor (ACEI) at referral. Many patients are referred late for dialysis despite early signs of renal failure, and the pre-referral management of many of the patients, as evidenced by the treatment of hypertension and use of ACEI in diabetics, is less than optimal.  (+info)

Ex vivo evaluation of a Taylor-Couette flow, immobilized heparinase I device for clinical application. (2/652)

Efficient and safe heparin anticoagulation has remained a problem for continuous renal replacement therapies and intermittent hemodialysis for patients with acute renal failure. To make heparin therapy safer for the patient with acute renal failure at high risk of bleeding, we have proposed regional heparinization of the circuit via an immobilized heparinase I filter. This study tested a device based on Taylor-Couette flow and simultaneous separation/reaction for efficacy and safety of heparin removal in a sheep model. Heparinase I was immobilized onto agarose beads via cyanogen bromide activation. The device, referred to as a vortex flow plasmapheretic reactor, consisted of two concentric cylinders, a priming volume of 45 ml, a microporous membrane for plasma separation, and an outer compartment where the immobilized heparinase I was fluidized separately from the blood cells. Manual white cell and platelet counts, hematocrit, total protein, and fibrinogen assays were performed. Heparin levels were indirectly measured via whole-blood recalcification times (WBRTs). The vortex flow plasmapheretic reactor maintained significantly higher heparin levels in the extracorporeal circuit than in the sheep (device inlet WBRTs were 1. 5 times the device outlet WBRTs) with no hemolysis. The reactor treatment did not effect any physiologically significant changes in complete blood cell counts, platelets, and protein levels for up to 2 hr of operation. Furthermore, gross necropsy and histopathology did not show any significant abnormalities in the kidney, liver, heart, brain, and spleen.  (+info)

Incidence of analgesic nephropathy in Berlin since 1983. (3/652)

BACKGROUND: Phenacetin was removed from the German market in 1986 and was replaced mainly in analgesic compounds by acetaminophen. Our objective was to examine the effect of this measure on the incidence of analgesic nephropathy in light of the changes in other end-stage renal diseases. METHODS: We therefore compared the proportion of renal diseases in all patients starting dialysis treatment during three 18-month periods: 4/1982-9/1983 (n=57); 1/1991-6/1992 (n=81); and 10/1995-3/1997 (n=76). RESULTS: On the one hand, the proportion of end-stage analgesic nephropathy decreased significantly from 30% in 1981-1982 to 21% in 1991-1992 and 12% in 1995-1997 (P=0.01). On the other hand, type II diabetes increased significantly from 7% to 22% (P=0.01) and 29%, (P=0.001). Using the chi2 distribution test to analyze the frequencies of seven diseases at three different time intervals, however, showed that the changes in renal-disease proportions between 1982-1983, 1991-1992 and 1995-1997 were not significantly independent. There was a significant median age increase from 52 years (CI0.95 44-58) in 1982-1983 to 63 (CI0.95 55-67) in 1991-1992 and 63 (CI0.95 60-66) in 1995-1997 (P=0.003) for all patients starting dialysis but not for those with analgesic nephropathy [59 (55-71) vs 64 (53-67) and 61 (50-72); n.s.]. CONCLUSION: The decrease of end-stage analgesic nephropathy since 1983 may be partially due to the removal of phenacetin from the German market in 1986. However, considering the general increase in numbers of dialysis patients, their higher age and the increased incidence of type II diabetes, the decrease in analgesic nephropathy is not a statistically significant independent variable. Altered admittance policies for dialysis treatment have yielded a new pattern of renal-disease proportion which interferes with changes in the incidence of analgesic nephropathy.  (+info)

La roca magica: uses of natural zeolites in agriculture and industry. (4/652)

For nearly 200 years since their discovery in 1756, geologists considered the zeolite minerals to occur as fairly large crystals in the vugs and cavities of basalts and other traprock formations. Here, they were prized by mineral collectors, but their small abundance and polymineralic nature defied commercial exploitation. As the synthetic zeolite (molecular sieve) business began to take hold in the late 1950s, huge beds of zeolite-rich sediments, formed by the alteration of volcanic ash (glass) in lake and marine waters, were discovered in the western United States and elsewhere in the world. These beds were found to contain as much as 95% of a single zeolite; they were generally flat-lying and easily mined by surface methods. The properties of these low-cost natural materials mimicked those of many of their synthetic counterparts, and considerable effort has made since that time to develop applications for them based on their unique adsorption, cation-exchange, dehydration-rehydration, and catalytic properties. Natural zeolites (i.e., those found in volcanogenic sedimentary rocks) have been and are being used as building stone, as lightweight aggregate and pozzolans in cements and concretes, as filler in paper, in the take-up of Cs and Sr from nuclear waste and fallout, as soil amendments in agronomy and horticulture, in the removal of ammonia from municipal, industrial, and agricultural waste and drinking waters, as energy exchangers in solar refrigerators, as dietary supplements in animal diets, as consumer deodorizers, in pet litters, in taking up ammonia from animal manures, and as ammonia filters in kidney-dialysis units. From their use in construction during Roman times, to their role as hydroponic (zeoponic) substrate for growing plants on space missions, to their recent success in the healing of cuts and wounds, natural zeolites are now considered to be full-fledged mineral commodities, the use of which promise to expand even more in the future.  (+info)

Diagnosis and treatment of chronic renal failure in children. (5/652)

This activity is designed for primary care and specialist physicians. GOAL: To provide an overview of the unique features and treatment of chronic renal failure in children. OBJECTIVES: 1. Describe the diagnosis of chronic renal failure in children. 2. Discuss the medical treatment of chronic renal failure in children. 3. Understand the treatment of end-stage renal disease in children. 4. Discuss the financial impact of caring for a child with chronic renal failure.  (+info)

Annual Report of the German Renal Registry 1998. QuaSi-Niere Task Group for Quality Assurance in Renal Replacement Therapy. (6/652)

During the past 3 years, the basis of a German Renal Registry has been established. An agreement between end-stage renal disease (ESRD) therapy providers, insurance companies and the government has been reached to fund and support the registry office and its electronic data base. An overall acceptable compliance has been achieved to provide data voluntarily, although in the future the data submission will have to be mandatory to achieve complete data sampling within an acceptable time frame. In Germany, 713 patients per million population (p.m.p.) are on renal replacement therapy (RRT). The incidence of new patients commencing RRT is 156 p.m.p. These numbers are comparable with those reported from other European countries such as France, Italy and Spain, but significantly lower than those reported from the US or Japan. More than 92% of all dialysis patients are treated by haemodialysis and only a limited number with peritoneal dialysis. Approximately 25% of the patients have a functioning kidney graft. The transplantation rate of 25 p.m.p. is far from sufficient if compared with Spain, Austria or the US. Although an increasing number of diabetic patients commenced RRT, the percentage, i.e. approximately 30%, is less than in the US or Japan. The annual growth of the population on renal replacement cannot currently be given precisely because the database is still limited, but it seems to be approximately 3-4%.  (+info)

End-stage renal disease in Canada: prevalence projections to 2005. (7/652)

BACKGROUND: The incidence and prevalence of end-stage renal disease (ESRD) have increased greatly in Canada over the last 2 decades. Because of the high cost of therapy, predicting numbers of patients who will require dialysis and transplantation is necessary for nephrologists and health care planners. METHODS: The authors projected ESRD incidence rates and therapy-specific prevalence by province to the year 2005 using 1981-1996 data obtained from the Canadian Organ Replacement Register. The model incorporated Poisson regression to project incidence rates, and a Markov model for patient follow-up. RESULTS: Continued large increases in ESRD incidence and prevalence were projected, particularly among people with diabetes mellitus. As of Dec. 31, 1996, there were 17,807 patients receiving renal replacement therapy in Canada. This number was projected to climb to 32,952 by the end of 2005, for a relative increase of 85% and a mean annual increase of 5.8%. The increased prevalence was projected to be greatest for peritoneal dialysis (6.0% annually), followed by hemodialysis (5.9%) and functioning kidney transplant (5.7%). The projected annual increases in prevalence by province ranged from 4.4%, in Saskatchewan, to 7.5%, in Alberta. INTERPRETATION: The projected increases are plausible when one considers that the incidence of ESRD per million population in the United States and other countries far exceeds that in Canada. The authors predict a continued and increasing short-fall in resources to accommodate the expected increased in ESRD prevalence.  (+info)

Long-term outcome of dialysis patients in the United States with coronary revascularization procedures. (8/652)

BACKGROUND: The optimal method of coronary revascularization in dialysis patients is controversial, as previous small retrospective studies have reported increased cardiac events after percutaneous transluminal coronary angioplasty (PTCA) compared with coronary artery bypass (CAB) surgery. The purpose of this study was to compare the long-term survival of chronic dialysis patients in the United States following PTCA or CAB surgery. METHODS: Dialysis patients hospitalized from 1978 to 1995 for first coronary revascularization procedure after initiation of renal replacement therapy were retrospectively identified from the United States Renal Data System database. Survival for the endpoints of all-cause death, cardiac death, myocardial infarction, and cardiac death or myocardial infarction was estimated by the life-table method and was compared by the log-rank test. The impact of independent predictors on survival was examined in a Cox regression model with comorbidity adjustment. RESULTS: The in-hospital mortality was 5.4% for 6887 PTCA patients and 12.5% for 7419 CAB patients. The two-year event-free survival (+/-SE) of PTCA patients was 52.9 +/- 0.7% for all-cause death, 72.5 +/- 0.7% for cardiac death, and 62.0 +/- 0.7% for cardiac death or myocardial infarction. In CAB patients, the comparable survivals were 56.9 +/- 0.6, 75.8 +/- 0.6, and 71.3 +/- 0. 6%, respectively (P < 0.02 for PTCA vs. CAB surgery for all endpoints). After comorbidity adjustment, the relative risk of CAB surgery (vs. PTCA) performed 1990 to 1995 for all-cause death was 0. 91 (95% CI, 0.86 to 0.97); cardiac death, 0.85 (95% CI, 0.78 to 0. 92); myocardial infarction, 0.37 (95% CI, 0.32 to 0.43); and cardiac death or myocardial infarction 0.69 (95% CI, 0.64 to 0.74). CONCLUSIONS: In this retrospective study, dialysis patients in the United States had better survival after CAB surgery compared with PTCA, but our study does not exclude the possibility of more unfavorable coronary anatomy in the PTCA patients at baseline. Our data support the need for prospective trials of newer percutaneous coronary revascularization procedures in dialysis patients.  (+info)

According to the latest report published by Credence Research, Inc. Continuous Renal Replacement Therapy Market - Growth, Future Prospects and Competitive Analysis, 2017-2025, the global continuous renal replacement therapy market was valued at US$ 856.2 Mn in 2016, and is expected to reach US$ 1,653.8 Mn by 2025, expanding at a CAGR of 7.47% from 2017 to 2025.. Browse the full report Continuous Renal Replacement Therapy Market - Growth, Future Prospects and Competitive Analysis, 2017-2025 at http://www.credenceresearch.com/report/continuous-renal-replacement-therapy-market. Market Insights Acute dialysis-dependent renal failure is a common issue in ICU patients. Despite significant improvement in patient care in ICUs, the mortality arising from acute renal failure in ICU remains at over 50%. Over the past 20 years, significant improvement has taken place in the field of hemodialysis and the approach to the treatment of acute renal failure has underwent transformation. Use of novel, user ...
TY - JOUR. T1 - Comparative effectiveness of liver transplant strategies for end-stage liver disease patients on renal replacement therapy. AU - Chang, Yaojen. AU - Gallon, Lorenzo. AU - Jay, Colleen. AU - Shetty, Kirti. AU - Ho, Bing. AU - Levitsky, Josh. AU - Baker, Talia. AU - Ladner, Daniela. AU - Friedewald, John. AU - Abecassis, Michael. AU - Hazen, Gordon. AU - Skaro, Anton I.. PY - 2014/1/1. Y1 - 2014/1/1. N2 - There are complex risk-benefit tradeoffs with different transplantation strategies for end-stage liver disease patients on renal support. Using a Markov discrete-time state transition model, we compared survival for this group with 3 strategies: simultaneous liver-kidney (SLK) transplantation, liver transplantation alone (LTA) followed by immediate kidney transplantation if renal function did not recover, and LTA followed by placement on the kidney transplant wait list. Patients were followed for 30 years from the age of 50 years. The probabilities of events were synthesized from ...
Acute renal replacement therapy is one of the most common interventions provided by nephrologists, however, data on the quality of training provided to nephrology fellows is limited. Extensive curricula for acute renal replacement therapy and the management of poisonings and intoxications have been published, but personal experience suggests that there are significant opportunities to improve training. Particular areas to be considered include the use of novel technologies for assessment of volume status, greater emphasis on the dosing of medications during acute renal replacement therapy, greater training in assessing and tailoring treatment to the goals of care of the individual patient, incorporation of continuous quality improvement tools into the management of acute renal replacement therapy programs and development of robust simulation training to augment training ...
The Global Continuous Renal Replacement Therapy (CRRT) Market is expected to reach USD 1.4 billion by 2025, according to a new report by Grand View Research, Inc. The magnitude of the global target diseases, such as kidney diseases, and diabetes, is immense, with millions of new cases registered every year. This in turn is anticipated to boost the usage of CRRT treatment procedure.. Increasing incidence of volume overload, uremia, and hyperkalemia is increasing the application of renal replacement therapy, thereby boosting the overall growth of the market. For individuals suffering from acute kidney injury and severe multi-organ dysfunction, CRRT can prove to be beneficial when started early to maintain metabolic and volume homeostasis. In addition, CRRT prevents further worsening and development of symptoms and signs of renal failure. Full Research Report on Global Continuous Renal Replacement Therapy Market Analysis ...
China ICU Cbp Crrt Continuous Renal Replacement Therapy Machine, Find details about China Hemodialysis Machine, Dialysis Machine from ICU Cbp Crrt Continuous Renal Replacement Therapy Machine - Anjue Medical Equipment Co., Ltd.
Continuous Renal Replacement Therapy (CRRT) is the standard of care for management of critically ill patients with acute renal failure. Part of the Pittsburgh Critical Care series, Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance about this treatment modality, offering quick reference answers to clinicians questions about treatments and situations encountered in daily practice.
The management of perioperative patients with severe acute kidney injury (AKI), and its associated complications, is mostly supportive and includes renal replacement therapy (RRT). Available RRT modalities are intermittent hemodialysis (IHD), peritoneal dialysis (PD), continuous renal replacement therapy (CRRT), and hybrid therapies, known as prolonged intermittent renal replacement therapy (PIRRT). This chapter reviews the current evidence regarding the timing of initiation of RRT, the modality selection, and the critical elements of the RRT prescription for AKI in the postoperative period ...
INTRODUCTION This work is focused on mapping issues of hemostasis in patients during continuous renal replacement therapy, or the possible impact of the use of anticoagulants. METHODS The study included 30 consecutive patients requiring continuous renal replacement therapy following cardiac surgery in the period of 2009 to 2012. Patients were placed into 2 branches according to the selected method of anticoagulation (regional citrate anticoagulation-RCA, unfractionated heparin UFH). According to the given scheme (t1-t7) thromboelastography and laboratory testing related to the testing of blood clotting during continuous renal replacement therapy were performed. RESULTS The average lifespan of a hemofilter during continuous renal replacement is 58.13 ± 9.968 hours. During continuous renal replacement therapy there are significant changes in the initiation of coagulation according to thromboelastographic parameters (R, K, alpha angle) in both branches of anticoagulation. The maximum image changes in
The impact of Continuous Renal Replacement Therapy (CRRT) on the outcomes of patients with sepsis is controversial, and there is no consensus for the timing and dose of CRRT may improve the outcomes. The purpose of this prospective randomized study is to assess the effect of different CRRT intensity (25ml/kg/h or 50ml/kg/h) on the outcomes of burn patients with early phase of ...
The Continuous Renal Replacement Therapy (CRRT) Market is projected to reach USD 1.53 Billion by 2022 from USD 1.09 Billion in 2017, at a CAGR of 7.0%.
Free Online Library: Evaluation of Continuous Renal Replacement Therapy Effluent to Assess Filtration Efficiency of Dialyzers in Renal Failure dogs.(Clinical Article) by Intas Polivet; Health, general Chronic kidney failure Care and treatment Dogs Urea
VCU Health CME, 9th International Conference on Pediatric Continuous Renal Replacement Therapy (pCRRT), 8/31/2017 6:00:00 AM - 9/2/2017 2:30:00 PM, |p>|span>|span style=font-size: 16px;>|span style=color: rgb(0, 0, 0);>|span style=color: rgb(192, 0, 0); font-family: "Segoe UI", Arial, Helvetica, sans-serif; font-size: 14px; background-color: rgb(255, 255, 255);>|strong>|span style=text-decoration: underline;>As we must ship everything to Florida, ONLINE, FAX AND PHONE registration ARE CLOSED.  We have room for you to join us and REGISTRATIONS WILL BE ACCEPTED ONSITE.|/span>|/strong>|/span>|/span>|/span>|/span>|/p>|p>|strong style=color: rgb(192, 0, 0); font-family: "Segoe UI", Arial, Helvetica, sans-serif; font-size: 14px;>|span style=text-decoration-line: underline;>IF YOU NEED A HOTEL AT DISNEY - Please contact CRICKET directly at 804-828-5414|/span>|/strong>|br>|/p>|p>|span>|span style=font-size: 16px;>|span style=color: rgb(0, 0, 0);>|span style=color: rgb
MEASUREMENTS AND MAIN RESULTS: Data from 30 studies were analyzed. The mean age of the patient groups involved in studies of meropenem, piperacillin, and vancomycin were 55.3, 60.3, and 56.9 years, respectively. The mean blood and effluent flow rates used for each antibiotic were 151.3 and 33.8 mL/min, 131.8 and 27.3 mL/min, and 189.3 and 35.6 mL/min, respectively, in continuous renal replacement therapy studies. Correlations existed between effluent flow rate in continuous renal replacement therapy and extracorporeal clearance for meropenem (rs = 0.43; p = 0.12), piperacillin (rs = 0.77; p = 0.10), and vancomycin (rs = 0.90; p = 0.08). Current dosing regimens achieved target concentrations for meropenem (89%), piperacillin (83%), and vancomycin (60%) against susceptible pathogens ...
Acute renal replacement therapy is one of the most common interventions provided by nephrologists, however, data on the quality of training provided to nephrology fellows is limited. Extensive curricula for acute renal replacement therapy and the management of poisonings and intoxications have been published, but personal experience suggests that there are significant opportunities to improve training. Particular areas to be considered include the use of novel technologies for assessment of volume status, greater emphasis on the dosing of medications during acute renal replacement therapy, greater training in assessing and tailoring treatment to the goals of care of the individual patient, incorporation of continuous quality improvement tools into the management of acute renal replacement therapy programs and development of robust simulation training to augment training ...
The increase in acute kidney injury in COVID-19 patients is resulting in more utilization of renal replacement therapy (RRT) and continuous renal replacement therapy. Host Pamela M. Peeke, MD, MPH, FACP, FACSM , is joined by Michael J. Connor Jr, MD, to review RRT utilization.
Fluid overload is associated with morbidity and mortality in patients receiving renal replacement therapy (RRT). We aimed to explore whether fluid overload at initiation of RRT was independently associated with mortality and whether changes in cumulative fluid balance during RRT were associated with outcome. We retrospectively analysed the data of patients who were admitted to the multidisciplinary adult intensive care unit (ICU) in a tertiary care centre in the UK between 2012 and 2015 and received continuous RRT (CRRT) for acute kidney injury for at least 24 h. We collected baseline demographics, body mass index (BMI), comorbidities, severity of illness, laboratory parameters at CRRT initiation, daily cumulative fluid balance (FB), daily prescribed FB target, fluid bolus and diuretic administration and outcomes. The day of the lowest cumulative FB during CRRT was identified as nadir FB. Eight hundred twenty patients were analysed (median age 65 years; 49% female). At CRRT initiation, the median
Mobilization of patients with femoral vascular catheters receiving CRRT in the ICU was safe and feasible. The intervention did not result in vascular catheter dislodgement, haematoma or bleeding, and there were no detectable clinical sequelae, including suspected thrombosis or filter circuit disruption. Average pressures did not approach circuit failure definitions (TM pressure ,250 mmHg and access pressure ,200 mmHg [26]) in any intervention group. These findings have significant implications for clinical practice situations where patients on CRRT are unnecessarily restrained from movement because of the perceived importance of these restrictions to maintaining filter patency and filter life and reducing mortality [27]. Interruptions in CRRT impact the dose of therapy delivered as well as clinical outcomes [27]. Testing mobilization during CRRT is critical, given that the opportunity to mobilize off CRRT can be minimal (minimum 16 hours required to maintain urea and creatinine, with a median ...
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Renal replacement therapy, in the form of dialysis or transplantation, is the cornerstone of management for end-stage renal disease. UK renal registry shows nearly half of those needing renal replacement therapy are treated by dialysis - predominantly by haemodialysis. Patients on renal replacement therapy have increased mortality risk compared to age matched general population. Moreover, some specific subgroups of patients on haemodialysis have increased risk of mortality than expected. The survival benefit seen in women in the general population is attenuated resulting in similar survival for men and women on haemodialysis therapy. In addition, obese individuals and those of non-Caucasian origin have better survival outcome. Though the underlying reason for these findings is not clear and is likely to be multi-factorial, it has been hypothesised that this paradox could be due to the current practice of normalising dialysis dose to total body water. A number of metabolic factors - body surface ...
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Acute renal failure (ARF) is rarely an isolated process but is often a complication of underlying conditions such as sepsis, trauma, and multiple-organ failure in critically ill patients. As such, concomitant clinical conditions significantly affect patient outcome. Poor nutritional status is a major factor in increasing patients morbidity and mortality. Malnutrition in ARF patients is caused by hypercatabolism and hypermetabolism that parallel the severity of illness. When dialytic intervention is indicated, continuous renal replacement therapy (CRRT) is a commonly used alternative to intermittent hemodialysis because it is well tolerated by hemodynamically unstable patients. This paper reviews the metabolic and nutritional alterations associated with ARF and provides recommendations regarding the nutritional, fluid, electrolyte, micronutrient, and acid-base management of these patients. The basic principles of CRRT are addressed, along with their nutritional implications in critically ill ...
Although the worldwide standard for renal replacement therapy is intermittent hemodialysis(IHD), continuous renal replacement therapy (CRRT) has emerged as an alternative form of renal replacement therapy in the critical care setting due to its advantages of slow continuous fluid removal, steady acid-base correction, and hemodynamic stability.. There are no standard protocols for initiating or administering CRRT, and practice patterns vary widely among institutions, with less than 25% of patients with ARF in the ICU receiving this therapy in the United States.. Various CRRT modalities are available that use diffusion, convection, or a combination of both to obtain adequate solute clearance. However, there is no consensus as to the optimal dialysis modality, adequate dialysis dose, or optimal clearance modality (convection vs. diffusion). Clinical trials are needed to determine the optimal method of administering CRRT, with respect to modality, dose of dialysis, and time of initiation of ...
There is an increasing incidence and prevalence of AKI globally [1, 7, 11] and severe AKI is associated with increased mortality up to greater than 50% [12-14]. In the absence of effective pharmacologic interventions for severe AKI, renal replacement therapy remains the main supportive management, and therefore is one of the critical aspects for improvement to achieve the goal of ISN AKF 0 by 25. However, up to now little is known about the need, availability, and maneuverability of RRT in the clinical practice in developing countries. Based on the nationwide survey of AKI in over 2 million adult hospitalizations, we were able to estimate the burden of RRT need and the real state of RRT performance in Mainland China [9].. Although there are some disagreements about the optimal timing for initiating RRT in AKI patients, there is no doubt that RRT should be performed in patients with life-threatening conditions including overt fluid imbalance, electrolyte abnormalities, acid-base disturbances, ...
The 2012 ERA-EDTA Registry Annual Report contains both good news and bad news. On the bright side, the 2-year survival of patients starting renal replacement therapy (RRT) for chronic kidney disease (CKD), on dialysis or receiving a living-related kidney transplantation, has progressively increased to 82.2, 79.7 and 98.3%, respectively, whereas for cadaveric kidney transplantation it remains stable (96.0-96.1%). On the dark side, inequalities persist between European citizens in access to renal transplantation and in incidence and prevalence of RRT. Living in Greece, Belgium (French- or Dutch-speaking) or Portugal (the GBP countries) is associated with higher chances of initiating RRT than living in other European countries. The adjusted RRT incidence for GBP countries was 188, 201-174 and 220* (* unadjusted) pmp in 2012, respectively (versus 122, 114 and 97 pmp in the Netherlands or two Spanish regions bordering Portugal). In lower income countries, a low RRT incidence may represent lack of ...
Renal replacement therapy (RRT) is required when the kidneys are poorly functioning. Forms of RRT include dialysis, hemodialysis, peritoneal dialysis, and kidney transplant. In hemodialysis, blood is drawn intravenously and sent through a machine called a dialyzer. The blood is circulated and diffused numerous times during a dialysis session; each circulation through the machine removing more waste and excess fluid in a process known as ultrafiltration. The blood is then returned to the body through a blood vessel. Hemodialysis is usually performed three or more times a week for 4 hours or more.
Acute kidney injury (AKI) is a common and devastating complication of critical illness. Once AKI is established, treatment is largely supportive and no intervention has been found to restore kidney function or improve overall survival. Renal replacement therapy (RRT), usually in the form of hemodialysis, is frequently needed to manage patients with severe AKI. Such patients have an in-hospital mortality that consistently exceeds 50% with delays in RRT initiation implicated as a possible contributor. A recent meta-analysis suggested that earlier initiation of RRT may improve survival, but this is based on data derived overwhelmingly from observational studies. The investigators recently completed a multi-centre randomized controlled pilot trial that confirmed the feasibility of allocating patients to two different strategies of RRT initiation. Patient recruitment and follow-up, as well as patient safety, were successfully demonstrated during the pilot phase of this research program. The optimal ...
Background: The annual gross mortality of end-stage renal failure patients remains very high (approximately 15-20%) leading some to question the wisdom of accepting patients with limited prognosis for dialysis. We have reviewed the demographic and clinical characteristics of patients who died within a year of commencing renal replacement therapy (RRT) over a 5-year period to establish whether these patients could be identified at the start of therapy. Methods: Case notes of patients who died within 1 year of commencing RRT between 1st April, 1991 and 31st March, 1996 were reviewed. Comorbidity at the start of dialysis was used to classify patients into high-, medium- and low-risk groups using two published scales to determine whether either graded a high proportion of deaths as high risk. Factors such as age, social circumstances, cause of death, renal diagnosis and mode of dialysis were also analysed. Results: 17.5% of patients commencing RRT died in the first year. Not all of these patients could be
Objective: To report circuit characteristics and survival analysis in children weighing ≤10 kg enrolled in the Prospective Pediatric Continuous Renal Replacement Therapy (ppCRRT) Registry. Study design: We conducted prospective cohort analysis of the ppCRRT Registry to: (1) evaluate survival differences in children ≤10 kg compared with other children; (2) determine demographic and clinical differences between surviving and non-surviving children ≤10 kg; and (3) describe continuous renal replacement therapy (CRRT) circuit characteristics differences in children ≤5 kg versus 5-10 kg. Results: The ppCRRT enrolled 84 children ≤10 kg between January 2001 and August 2005 from 13 US tertiary centers. Children ≤10 kg had lower survival rates than children , 10 kg (36/84 [43%] versus 166/260 [64%] ; P , .001). In children ≤10 kg, survivors were more likely to have fewer days in intensive care unit prior to CRRT, lower Pediatric Risk of Mortality 2 scores at intensive care unit admission and ...
An integrated CRRT method and apparatus incorporates steps and means for compensating for heat loss from blood in an extracorporeal circuit. A blood warmer is designed to engage and hold a disposable blood tube segment to transfer heat at a closely controlled temperature to blood flowing in the disposable blood tube segment. Another significant aspect of the present invention is a blood tube segment for engagement with the blood warmer is located in downstream of a dialyzer and upstream of a venous pressure monitor, an air bubble detector and a venous line clamp. The disposable blood tube segment may be selectively connected when heat loss compensation is required and left disconnected when heat loss compensation is not required.
Impaired renal function is associated with a high risk of chronicity of hepatitis B virus (HBV) infection. Patients on hemodialysis (HD) or peritoneal dialysis are at an increased risk of viral transmission due to frequent necessity of blood product transfer as well as use of contaminated dialysate or dialysis materials. Additionally, health professionals may cause viral spread via contaminated hands and carelessness against hygiene rules. The frequency of chronic HBV infection may be as high as 80% in patients on renal replacement therapies. This is because HBV vaccination is essential to eliminate chronic HBV infection. However, response rates of HD patients to HBV vaccination vary between 10%-50%. Dialysis adequacy and early vaccination before the onset of dialysis therapy seem to be major determinants of high seroconversion rates. Older age, male gender, duration of dialysis therapy and nutritional status are other well-known factors associated with seroconversion rate. There are ...
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A waste liquid collection system for use in continuous arteriovenous or venovenous hemodialysis (CAVH or CVVH) is disclosed. The system comprises a collection vessel and associated interconnection lines which can be preset to given volume of waste liquid to be removed from the dialysis machine in a given period of time. Once the volume is reached, the collection vessel stops waste liquid flow until the vessel is emptied and reset. The system guaranties that excess liquid will not be removed from a patient.
Few educational resources have been developed to inform patients renal replacement therapy (RRT) selection decisions. Patients progressing toward end stage renal disease (ESRD) must decide among multiple treatment options with varying characteristics. Complex information about treatments must be adequately conveyed to patients with different educational backgrounds and informational needs. Decisions about treatment options also require family input, as families often participate in patients treatment and support patients decisions. We describe the development, design, and preliminary evaluation of an informational, evidence-based, and patient-and family-centered decision aid for patients with ESRD and varying levels of health literacy, health numeracy, and cognitive function. We designed a decision aid comprising a complementary video and informational handbook. We based our development process on data previously obtained from qualitative focus groups and systematic literature reviews. We
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Renal replacement therapy is vital man-agement of renal failure. Hemodialysis is a hardware-based method of blood clearance, spread widely because of its efficacy. Renal failure morbidity is 150 - 200
Study 21 Renal Replacement Therapy: Dialysis Transplantation flashcards from Heather Acuff's class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
Results: The prevalence of dyslipidaemia was 85.1% in peritoneal dialysis (PD) patients, 76.1% in haemodialysis (HD) patients and 55.5% among renal allograft recipients. Both low and high body mass index (BMI) were associated with a less favourable lipid profile. Younger age was associated with a worse lipid profile among PD patients. HDL levels significantly improved after transplantation, whereas no significant improvements were found for triglyceride and non-HDL levels. In transplant recipients, use of cyclosporin was associated with significantly higher non-HDL and HDL levels than tacrolimus usage (P , 0.01). In transplant patients with eGFR , 29 mL/min/1.73 m2, the mean triglyceride level was 137 mg/dL (99% confidence interval (CI): 119-159) compared with 102 mg/dL among those with eGFR , 90 mL/min/1.73 m2 (P , 0.0001 ...
BACKGROUND: Twenty-five to 30% of new renal replacement therapy (RRT) patients present late to renal services. The proportion in whom this is avoidable, and whether awareness of chronic kidney disease (CKD) has reduced its incidence is not known. METHODS: Adult patients starting RRT (2003-2008) in a single unit were grouped according to the time interval between first presentation to the unit and start of RRT: |90 days (late presenters); 90-364 days; ≥ 365 days. Late presenters were classified as follows: acute kidney injury--patients who had acute but irreversible renal failure; avoidable late referrals, if they had known pre-existing CKD and unavoidable late referrals, if they had unpredictable rapid progression of their CKD or had no prior contact with health care. Mortality risk associated with late presentation was explored using multivariable Cox regression. RESULTS: Late presentation was common (24.3%) but late referrals accounted for only 7.4% and 3.9% were avoidable. The incidence of
Firstly HY Gee et al. publish in the J Clin Invest that KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. Then G Jean et al discuss in CKJ the Usefulness and feasibility of measuring ionized calcium in haemodialysis patients. Next SM Schneider et al. report in Nephrol. Dial. Transplant on the Effect of a single dialysis session on cognitive function in CKD5D patients: a prospective clinical study. Next B Li et al. again in NDT discuss Understanding cost of care for patients on renal replacement therapy: looking beyond fixed tariffs. Finally, Ray Vanholder et al. publish in Kidney int a paper entitled Once upon a time in dialysis: the last days of Kt/V ...
To study the impact of early human albumin solution (HAS) in continuous renal replacement therapy (RRT) patients. Analysis of Randomized Evaluation of Normal versus Augmented Level (RENAL) RRT trial data. Of 1,464 patients, 500 (34%) received early albumin. These patients had higher illness severity scores, greater use of mechanical ventilation, and 90-day mortality (51 vs. 41%; p , 0.001). However, early albumin carried similar RRT dependence risk among survivors at day 90 (4.9 vs. 5.8%; p = 0.62). On Cox proportional hazards regression, with standardized inverse probability of treatment weighting, early albumin was not associated with increased mortality (hazard ratio [HR]: 1.23, 95% CI: 0.97-1.55; p = 0.09) or recovery to RRT independence (HR: 0.92, 95% CI: 0.78-1.10; p = 0.38). Early albumin was administered to one-third of RENAL trial patients and in those with greater illness severity. Early albumin was not independently associated with mortality risk or rate of recovery to RRT independence ...
HAN IN MEE, RYU HAN JAK, KIM EUN JIN, PARK JUNG TAK, HAN SEUNG HYEOK, YOO TAE-HYUN, KANG SHIN-WOOK, CHOI KYU HUN, OH HYUNG JUNG Department of Internal Medicine, College of Medicine, Yonsei University Introduction: Continuous renal replacement therapy (CRRT) has been widely used in critically ill acute kidney injury (AKI) patients. Some centers consist of a specialized CRRT team (SCT). with physicians and nurses, but few studies have been yet reported on the superiority of SCT control. Methods: A total of 551 patients, who received CRRT between GS-1101 August 2007 and August 2009, divided into two groups based on the controller of CRRT. The impact of the CRRT management was compared between two groups. Results: The 28-day mortality rate was significantly lower in SCT group compared with conventional team approach (CTA) group (P = 0.031). In contrast, the number of used filters, total down-time, down-time per day, ICU length of day in CTA group were significantly higher compared to SCT. group (6.2 ...
Another reported reason in delaying RRT is the perception of impending renal recovery.25 RRT is invasive and can result in complications from access placement, hypotension, electrolyte abnormalities, and arrhythmias.13,29 Hemodynamic instability is common in the ICU and the intensivist needs to balance RRT safety with its need. Hypotension during RRT, along with issues of dialyzer bioincompatibility may delay renal recovery.30 Dialyzer membranes induce monocyte-derived proinflammatory cytokines (interleukin [IL] 1, 6, 8, tumor necrosis factor alpha [TNF-α]), which can increase renal toxicity. So-called biocompatible membranes may lessen these responses. Therefore when taken into account a prudent decision may be to wait and monitor volume, potassium, protein intake, and supplement bicarbonate as needed, selecting extended or continuous RRTs if condition worsens. Recently published AKIKI trial with early vs late initiations of RRT in critically ill patients suggest delaying initiation based on ...
For patients with chronic kidney disease (CKD) who develop kidney failure, renal replacement therapy (RRT) with kidney transplantation is the best treatment option. But if this is not possible due to lack of organs or medical factors, dialysis initiation with haemodialysis (HD) or peritoneal dialysis (PD) is required. Unplanned start (UPS) of dialysis using in-centre HD with central venous catheter (CVC) as default option is common and associates with increased mortality and lower chance of receiving PD. Educating and providing PD to UPS patients is possible and with clinical outcomes comparable to UPS with HD. As RRT patients have increased cardiovascular disease (CVD) related mortality - due to not only traditional risk factors but also non-traditional risk factors such as inflammation, oxidative stress, endothelial dysfunction and protein energy wasting - there is a need to identify biomarkers reflecting such risk factors ...
Continuous renal replacement therapies (CRRTs) have advantages over intermittent hemodialysis in the treatment of critically ill patients with acute renal failure (ARF). These benefits include:Improved cardiovascular stabilityImproved tolerance to ul
Looking for online definition of continuous renal replacement therapy in the Medical Dictionary? continuous renal replacement therapy explanation free. What is continuous renal replacement therapy? Meaning of continuous renal replacement therapy medical term. What does continuous renal replacement therapy mean?
TY - JOUR. T1 - Assessing continuous renal replacement therapy as a rescue strategy in cardiorenal syndrome 1. AU - Prins, Kurt W.. AU - Wille, Keith M.. AU - Tallaj, Jose A.. AU - Tolwani, Ashita J.. PY - 2015/12/18. Y1 - 2015/12/18. N2 - Background Patients with acute decompensated heart failure (ADHF) and cardiorenal syndrome (CRS) 1 have poor outcomes. Ultrafiltration (UF) is used to mechanically remove salt and water in ADHF patients with diuretic resistance. However, little is known about the outcomes of ADHF patients on inotropes and/or vasopressors who require continuous renal replacement therapy (CRRT) for both UF and solute clearance in severe acute kidney injury. Methods We retrospectively analyzed 37 consecutive critically ill patients who were admitted for ADHF from 2005-13 and were on inotropes and/or vasopressors at the time of CRRT initiation. The primary outcome was in-hospital mortality. Results In-hospital mortality rate was 62%. Median survival was 15.5 days after CRRT ...
Dialysis may be required in patients with severe acute kidney injury (AKI, acute renal failure [ARF]). Most patients have been treated with hemodialysis, with the dialysis prescription varying in part with the presence or absence of hypercatabolism.
This study was designed to elucidate the expression of renal tissue cytokines by receiving concomitant ECMO and CRRT in the healthy swine model. Our results showed that it might remove ECMO-induced cytokines, maintain the role of immune equilibrium, reduce the extent of ECMO-related SIRS, thereby leading to improve ECMO-related acute renal dysfunction.. CRRT was applied to acute renal failure patients have been widely recognized. CRRT matched with human kidney by continuously, slowly and convection running. Its mainly advantage is that it could stabilize the hemodynamic, improve azotemia, electrolytes and water-salt metabolism, keep on cleaning cycle of all sorts of cytokines and improve nutrition [10-13].. Previous animal experiments and clinical studies have shown that blood components are continually exposed to non-biological artificial surface from cardiopulmonary bypass pipe and changes of the non-physiological hemorheology during ECMO running. This leads to the complement system, the ...
A comprehensive course on Acute Kidney Injury and Renal Replacement Therapy as part of the Advanced Critical Care Therapeutic course. The Advanced Critical Care Therapeutic course provides in-depth advanced instruction concerning the pharmacotherapeutic management of commonly encountered critical care diseases. Emphasis is placed on the efficacy, safety, and comparative value of drug therapy in this highly specialized practice area. Didactic knowledge of physiology, pharmacology, and drug therapy management is applied to disease states specific to this population. Didactic instruction is combined with practice case studies and interactive discussions concerning critical care pharmacy-related issues. Participants may download materials.
Sepsis-Associated Acute Kidney Injury: Is COVID-19 different? Kidney Int. 2020 Sep 10.. View in PubMed. MELD-GRAIL-Na: Glomerular Filtration Rate and Mortality on Liver-Transplant Waiting List Hepatology. 2020 May; 71(5):1766-1774. . View in PubMed. Reply to: Lack of evidence for a continuum between hepatorenal syndrome and acute tubular necrosis J Hepatol. 2020 Mar; 72(3):582-583. . View in PubMed. Community Health Care Quality Standards to Prevent Acute Kidney Injury and Its ConsequencesAm J Med. 2020 05; 133(5):552-560. e3. . View in PubMed. Outcomes of Liver Transplantation in Patients on Renal Replacement Therapy: Considerations for Simultaneous Liver Kidney Transplantation Versus Safety Net Transplant Direct. 2019 Oct; 5(10):e490. . View in PubMed. News in pathophysiology, definition and classification of hepatorenal syndrome: A step beyond the International Club of Ascites (ICA) consensus document J Hepatol. 2019 10; 71(4):811-822. . View in PubMed. Acute kidney injury in cirrhosis: ...
International Journal of Nephrology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focusing on the prevention, diagnosis, and management of kidney diseases and associated disorders. The journal welcomes submissions related to cell biology, developmental biology, genetics, immunology, pathology, pathophysiology of renal disease and progression, clinical nephrology, dialysis, and transplantation.
Cardiovascular disease is the leading cause of the death in patients receiving chronic renal replacement therapy.1-3 Arteriovenous fistulas (AVFs) have superior longevity, lower infection and mortality rates and are associated with lower cost, and hence have become the vascular access of choice for patients needing dialysis.4 Indeed, the prevalence of AVFs in the United States increased from 32% of all dialysis access in 2003 to 61% in 2012.5,6 Despite their association with a lower mortality, AVFs have significant effects on cardiac functions predominantly related to the increase in preload and cardiac output (CO). This article reviews the potential effects of the creation and the ligation of AVFs on cardiac function and their mechanisms.. It should be emphasized, at the outset, that determining the exact effects of AVFs on cardiac functions is fraught with problems for a couple of reasons: patients with end stage renal disease (ESRD) requiring dialysis almost invariably have volume overload ...
We hypothesized that using consensus AKI definitions, enrolling sepsis-associated AKI, differences in sample sizes and study qualities had high impacts on patient outcomes observed among different investigations. When we used different AKI definitions, septic AKI, and study quality for subgroup analyses, we found no difference between earlier versus later RRT initiation time.. We found survival benefit for earlier RRT initiation when CRRT was utilized. Previous studies including one meta-analysis showed no difference in mortality or RRT dependence between various dialysis modalities [40, 43], while other meta-analyses showed that the use of CRRT decreases mortality or RRT dependence [42]. However, these findings largely were dependent on data from observational trials, which were potentially biased by allocation and the qualities were uncertain. Our analysis focused on RCTs, mostly with high qualities and appropriate randomization, and the results were more reliable. The possible mechanisms of ...
An analysis of 38 trials found no difference in the death rates, which are usually higher than 30 percent, for one method or another, according to a report in the Feb. 20 issue of the Journal of the American Medical Association.. Methods used in the various trials were continuous renal replacement therapy (CRRT), in which the person whose kidneys have failed gets continuous dialysis, a machine treatment that removes impurities from the blood, and intermittent hemodialysis, in which the purifying treatment is not continuous.. There doesnt seem to be any difference in any measurable outcome that has been evaluated in trials, said study author Dr. Neesh Pannu, an assistant professor of pathology and critical care medicine at the University of Alberta, in Edmonton. We were not able to identify any subgroup that might have any benefit from one method over the other.. But that cant be said with certainty because most of the trials were small, Pannu added. There has been a relatively small ...
Sharon Su, MD FAAP is the Medical Director for Pediatric Nephrology at Randall Childrens Hospital Emanuel The Pediatric Nephrology Division provides evaluation, diagnosis and management of acute and chronic kidney disease, fluid and electrolyte disorders and urinary system ailments, including: - Acute kidney injury - Bone and mineral metabolism disorder (renal osteodystrophy) - Chronic kidney disease and end-stage renal disease (ESRD) - Congenital renal malformations - Diabetic nephropathy - Glomerulonephritis - Hematuria - Hypertension - Kidney stones - Peritoneal dialysis and hemodialysis - Proteinuria and nephrotic syndrome - Recurrent urinary tract infections and vesicoureteral reflux (VUR) - Renal tubular disorders - Systemic lupus erythematosus Our services include: - Hemodialysis - Peritoneal dialysis - Continuous renal replacement therapy (CRRT) - Pediatric Ambulatory Blood Pressure Monitoring (ABPM) - Apheresis - Ultrasound-guided renal biopsies - Urine stone analysis - Urine ...
Comprehensive nutrition resource for Renal Support. Learn about the number of calories and nutritional and diet information for Renal Support. This is part of our comprehensive database of 40,000 foods including foods from hundreds of popular restaurants and thousands of brands.
A recently published nomenclature by a Kidney Disease Improving Global Outcomes (KDIGO) Consensus Conference suggested that the word kidney should be used in medical writings instead of renal or nephro when referring to kidney disease and kidney health. Whereas the decade-old move to use kidney more frequently should be supported when communicating with the public-at-large, such as the World Kidney Day, or in English speaking countries in communications with patients, care-partners, and non-medical persons, our point of view is that renal or nephro should not be removed from scientific and technical writings. Instead, the terms can coexist and be used in their relevant contexts. Cardiologists use heart and cardio as appropriate such as heart failure and cardiac care units and have not replaced cardiovascular with heartvessel, for instance. Likewise, in nephrology, we consider that chronic kidney disease and continuous renal replacement therapy should coexist. We ...
Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal replacement therapy. Randomised controlled trials (RCTs) and quasi-experimental studies examining the effects of exercise training on proteinuria in adults CKD patients without renal replacement therapy were searched in 10 electronic databases (MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database, SPORTDiscus with full text, Web of Science, China Wan Fang Database, China National Knowledge Internet, China Science and Technology Journal Database) until June 2019. The quality of quasi-experimental studies was assessed using the Joanna Briggs Institute Checklist for non-randomised experimental studies. The Cochrane risk of bias tool was used
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A 63 year old woman was admitted to the ICU from the Emergency Department with acute alcohol withdrawal, severe hyponatraemia (serum sodium level 114mmol/L), rhabdomyolysis (creatine kinase 46930u/L) and acute kidney injury (serum creatinine 262umol/L, urea 8.7mmol/L, potassium 4.6mmol/L, base excess -6.8 and anuric from the point of admission). Her corrected calcium level was 1.92mmol/L. She…
Extracorporeal therapies (ECT), such as hemodialysis, are critically important tools in the treatment of poisoned patients. In the last two decades, major changes have occurred in the nature, utilization, and availability of different types of ECT - including, among others, changes in hemodialysis filter technology, the rise of utilization of continuous renal replacement therapies, the sharp increase in the usage of extracorporeal membrane oxygenation in adults within the last five years, and a number of newly emerging therapies such as the extracorporeal liver assist device. Existing literature regarding the use of extracorporeal therapies to treat poisoning likely does not take all of these changes into account. The rate at which therapies are modified or introduced may make it difficult to adequately study use in poisoned patients through single-institution avenues, especially given that the use of ECT for all but a few poisonings is relatively rare. In addition, very detailed case ...
This aims to involve the whole multidisciplinary team and the patient in a conversation about nutrition. Formal assessment of nutrition status is time consuming and requires specific training and expertise. The NICE guidelines suggest that screening, which requires a simple and valid screening tool, is undertaken by health care workers to identify those at risk of malnutrition so that specialist dietitians can focus on those identified as at risk by screening.. The Malnutrition Universal Screening Tool (MUST) is recommended by NICE for population screening. This simple system can be taught to non-specialists, but it depends upon changes in weight. People with kidney disease tend to retain fluid as their kidney problem worsens and lose fluid when dialysis starts, so measures that depend upon actual body weight are not as reliable as usual. MUST has poor sensitivity in dialysis patients [19, 20].. The 2018 NICE guidance on renal replacement therapy (NG107) recognises that the relative number of ...
Registered nurses with varying experience and expertise in such areas as conservative management, hemodialysis, and continuous renal replacement therapies.
Amlodipine classified as a di-hyropyridine calcium channel blocker has an elimination half-life of 40 - 60 hours, a delayed onset of action and a large volume of distribution. We report a young pregnant lady who intentionally consumed 375 mg of Amlodipine and presented to us 20 hours later with severe hemodynamic instability which responded initially to a guideline directed treatment consisting of Calcium, Hyper insulin euglycemic therapy, glucagon, intralipid and vasopressor support. Other supportive therapies included mechanical ventilation and continuous renal replacement therapy in a CVVHD mode. However, the intention of reporting this case is to highlight the delayed effects of amlodipine which include a syndrome similar to systemic capillary leak syndrome with extensive peripheral edema, bilateral massive pleural effusions and a life-threatening pericardial effusion which needed immediate intervention. Due to paucity of literature in this area we hope that our case report improves the ...
The pre ESRD patient has an ongoing inflammatory process, which may or may not be aggravated by diabetes or congestive heart failure or infection. Then renal replacement therapy is imposed which is pro-inflammatory. The cascade of events results in all of the disease entities we see each day in the dialysis setting, ending in death. The picture that emerges is an ESRD patient who has an underlying permeating inflammatory disease that ultimately results in an unrelenting decline in health. I have omitted the evidence that confirms that the ESRD has markers of inflammation. I have further omitted those data showing the relationship of inflammation to the progression of cardiovascular disease and other clinical conditions seen in the ESRD population. And, I have omitted showing the relationship of inflammatory markers to morbidity and mortality. Renal replacement therapy prolongs life for a modest duration. At the same time, though, we may be aggravating the inflammatory response and accelerating ...
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Bello AK, Levin A, Lunney M, Osman MA, Ye F, Ashuntantang GE, Bellorin-Font E, Benghanem Gharbi M, Davison SN, Ghnaimat M, Harden P, Htay H, Jha V, Kalantar-Zadeh K, Kerr PG, Klarenbach S, Kovesdy CP, Luyckx VA, Neuen BL, ODonoghue D, Ossareh S, Perl J, Rashid HU, Rondeau E, See E, Saad S, Sola L, Tchokhonelidze I, Tesar V, Tungsanga K, Turan Kazancioglu R, Wang AY, Wiebe N, Yang CW, Zemchenkov A, Zhao MH, Jager KJ, Caskey F, Perkovic V, Jindal KK, Okpechi IG, Tonelli M, Feehally J, Harris DC, Johnson DW. Status of care for end stage kidney disease in countries and regions worldwide: international cross sectional survey. BMJ. 2019 10 31; 367:l5873 ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
TY - JOUR. T1 - Acute kidney injury: how can we facilitate recovery?. AU - Glassford, Neil John. AU - Bellomo, Rinaldo. N1 - 1531-7072 Glassford, Neil J Bellomo, Rinaldo Journal Article Review United States Curr Opin Crit Care. 2011 Dec;17(6):562-8. doi: 10.1097/MCC.0b013e32834cd334.. PY - 2011. Y1 - 2011. N2 - PURPOSE OF REVIEW: Successful renal recovery is a key goal of patient management during acute kidney injury in critically ill patients. However, limited information exists to guide clinicians as to what interventions might either decrease or increase the likelihood of renal recovery and especially renal recovery to dialysis independence. The purpose of this review is to analyse recent data and help clinicians with relevant therapeutic choices. RECENT FINDINGS: Two large trials, the Acute Renal Failure Trial Network (ATN) and Randomized Evaluation of Normal versus Augmented Level Renal Replacement Therapy (RENAL), provide important evidence on the possible impact of choice of renal ...
Acute kidney injury is characterized by abrupt deterioration in kidney function, manifested by an increase in serum creatinine level with or without reduced urine output. The spectrum of injury ranges from mild to advanced, sometimes requiring renal replacement therapy. The diagnostic evaluation can be used to classify acute kidney injury as prerenal, intrinsic renal, or postrenal. The initial workup includes a patient history to identify the use of nephrotoxic medications or systemic illnesses that might cause poor renal perfusion or directly impair renal function. Physical examination should assess intravascular volume status and identify skin rashes indicative of systemic illness. The initial laboratory evaluation should include measurement of serum creatinine level, complete blood count, urinalysis, and fractional excretion of sodium. Ultrasonography of the kidneys should be performed in most patients, particularly in older men, to rule out obstruction. Management of acute kidney injury involves
Purpose of review: Sustained low-efficiency dialysis (SLED) is increasingly used as a renal replacement modality in critically ill patients with acute kidney injury (AKI) and hemodynamic instability. There is, therefore, a greater need for the understanding of the antibiotic dosage and pharmacokinetics in these patients, to provide them with optimal therapy. Sources of information: PubMed/Medline, Embase, and Google Scholar. Methods: PubMed/Medline, Embase, and Google Scholar databases were searched using a combination of key words: dialysis, end stage renal disease, renal failure, sustained low efficiency dialysis, extended daily dialysis, prolonged intermittent renal replacement therapy (PIRRT), and antibiotic dosing. Studies that investigated antibiotic dosing and pharmacokinetics during SLED/extended daily dialysis/PIRRT were selected for this review. Key findings: Eleven studies met inclusion criteria and selected for data extraction. The data with regard to dialysis specifications, type of ...
Kidney disease is a global public health problem, affecting over 750 million persons worldwide. The burden of kidney disease varies substantially across the world, as does its detection and treatment. In many settings, rates of kidney disease and the provision of its care are defined by socio-economic, cultural, and political factors leading to significant disparities. World Kidney Day 2019 offers an opportunity to raise awareness of kidney disease and highlight disparities in its burden and current state of global capacity for prevention and management. Here, we highlight that many countries still lack access to basic diagnostics, a trained nephrology workforce, universal access to primary health care, and renal replacement therapies. We point to the need for strengthening basic infrastructure for kidney care services for early detection and management of acute kidney injury and chronic kidney disease across all countries and advocate for more pragmatic approaches to providing renal replacement ...
The Health Library is an online kidney disease resource for patients, family members and professionals brought to you by Renal Support Network.
Canine MCRC Renal Support + Hydrolyzed Protein is specially formulated to manage renal disease and assist in the management of adverse food reactions in the canine patient.Indications:• Renal disease (IRIS Stages III, IV)• Significant proteinuria/protein-losing nephropathy• Urate and cystine urolith prevention• Heart f
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The Renal Services Program at the University of Florida consists of separate inpatient and outpatient units for pediatric and adult patients. The nursing staff collaborates with other team members to care for patients receiving renal replacement therapy, for acute renal failure or End Stage Renal Disease.. Staff in the acute/pediatric unit have been cross-trained and are competent to treat acute adult patients as well as acute and chronic pediatric patients. Hemodialysis coverage for these populations is provided at Shands UF 24 hours a day, 7 days per week. The inpatient adult unit (acute dialysis) is a 6-station special care unit located on the hospitals fifth floor. The adult unit serves the medical/surgical population as well as a certain percentage of stable ICU/IMC patients. All patients with hemodynamic instability have their dialysis procedures performed at their bedside. The pediatric outpatient dialysis unit is a 5-station unit also located on the fifth floor of the hospital adjacent ...
Dr. Samir Tawakley has completed MBBS from University of Rajasthan in 1996 & DNB (Nephrology) from National Boaard of Examations in 2001 and has expertise in Kidney Disease Treatment, Urinary Tract Obstruction, Acute Renal Failure, Proteinuria, Peritoneal Dialysis, Chronic Kidney Disease ( CKD ), Diabetes Renal Failure, Renal Replacement Therapy, Acute Kidney Disease ( AKI ) Treatment, BP with Kidney Disease, Transplant Nephrology, Nephrology ICU, Blood in Urine (Hematuria) Treatment, Adult Nephrology etc ...
Clinical Research in Nephrology & Kidney Diseases is an International, Open access, Peer reviewed journal which encompasses various departments of Nephrology like clinical nephrology, diabetic nephropathy, pediatric nephrology, renal replacement therapy, dialysis and renal transplantation.
The Acute kidney injury: prevention, detection and management clinical guideline offers evidence-based advice on the prevention, detection and management of acute kidney injury up to the point of renal replacement therapy. ...
This manual provides practical and accessible information on all aspects of general nephrology, dialysis, and transplantation. It outlines current therapies in straightforward language to help readers understand the treatment rationale, and does not assume extensive knowledge of anatomy, biochemistry, or pathophysiology. Consisting of 33 chapters written by 31 experts from four continents, this volume covers all the practical tips in the emergency and long-term management of patients with electrolyte disturbance, acid-base disturbance, acute renal failure, common glomerular diseases, hypertension, pregnancy-related renal disorders, chronic renal failure, and renal replacement therapy. It is thus an essential source of quick reference for nephrologists, internists, renal fellows, and renal nursing specialists, and is also suitable for graduate students and research scientists in the field of kidney diseases.. Please Sign up/Log in to DOWNLOAD. ...
Acute kidney injury (AKI) is a serious complication in the perioperative period and is consistently associated with increased morbidity and case fatality rate. This has been best studied in the cardiac surgery setting where it has been shown that up to 11.5-86.0% of patients exposed to cardiopulmonary bypass (CPB) will develop AKI, with 2.0-18.9% requiring renal replacement therapy (RRT). A prospective uncontrolled cohort study was conducted between 2011 and 2015, in which 93 children with various congenital heart lesions undergoing CPB were enrolled. Serum creatinine (SCr) level was determined by Jaffés method (Cobas 6000 analyser, Roche). Postoperative fluid balance was estimated as the difference between fluid intake and output. Data for further processing were retrieved from anaesthesia and intensive care data management system flowsheets (IntelliView, Philips). AKI developed in 42 patients (45.6%) by meeting at least KDIGO (Kidney Disease: Improving Global Outcomes) stage I criteria (with ...
The number of Indians suffering from chronic kidney ailments has doubled in the past 15 years, and at present 17 in every hundred citizens suffer from some form of kidney disease, health experts have said.. The experts noted that several Indian population-based studies in the past estimated that some 150-230 persons suffer from End-Stage Kidney Disease (ESKD) in every million people, and about 2,20,000-2,75,000 new patients need Renal Replacement Therapy (RRT) every year.. The number of patients undergoing dialysis in India is also increasing by 10-15 per cent every year, which majorly includes children too. Not much importance is given to kidney disorders as it is still under-the-radar condition, said Sudeep Singh Sachdev, Consultant for Nephrology at Max Super Speciality Hospital.. According to the Health Ministry, 2,000 new dialysis centres will be set up at district-level hospitals in the country within the next two years, underlining the gravity of the problem.. The exact burden of ...
RIFLE criteria for acute kidney injury were used to compare the effects of vasopressin versus norepinephrine. In view of multiple simultaneous comparisons, a p value of 0.01 was considered statistically significant. Kidney injury was present in 464 patients (59.6%) at study entry. In patients in the RIFLE Risk category (n = 106), vasopressin as compared with norepinephrine was associated with a trend to a lower rate of progression to renal Failure or Loss categories (20.8 vs. 39.6%, respectively, p = 0.03), and a lower rate of use of renal replacement therapy (17.0 vs. 37.7%, p = 0.02). Mortality rates in the Risk category patients treated with vasopressin compared to norepinephrine were 30.8 versus 54.7%, p = 0.01, but this did not reach significance in a multiple logistic regression analysis (OR = 0.33, 99% CI 0.10-1.09, p = 0.02). The interaction of treatment group and RIFLE category was significant in predicting mortality.. ...
As highlighted by Health Issues India on World Kidney Day this year, living with kidney disease can prove expensive in India. 22,000 cases of end-stage renal disease (ESRD) are diagnosed every year. ESRD leaves patients in need of renal replacement therapy (RRT), which involves the use of medical processes such as dialysis to perform the role of the kidneys in patients whose kidneys no longer function properly. However, of the Indians in need of treatment with dialysis, a mere thirty percent can avail it. Of these, just ten to twenty percent continue with treatment - often due to affordability issues. NephroPlus, which operates 145 clinics in 86 cities across eighteen states as of last August, has said the amount owed by the state health department has been outstanding since last year. They say they have not received a response from officials despite efforts to contact them. As such, discontinuing free dialysis services at the affected clinics has become necessary as a last resort. Dr Ravindra ...
Hi, Im Jayson Albrey Sastre , 31 years old, a school teacher and a father to two great kids.I have been diagnosed with Chronic Kidney Diseases Stage 5 due to glomerulonephritis. My nephrologist have determined that my kidneys are only at 10 percent functionality so i would need to undergo renal replacement therapy (dialysis) to continue living. I have been undergoing treatment since August of 2019. I have experienced episodes of seizures on the first month of treatment since my blood toxins have reached a level greater than 2000 (creatinine) . Luckily, I have been getting better since then and I am currently on a biweekly hemodialysis schedule. I am very thankful for my family and friends who keep on supporting me. I am humbly wishing for good souls to help me out with my financial needs. I am very thankful for this treatment but this medical maintenance has taken a toll on my familys financial status. Please help me by donating whatever amount you can. All of it will go to a good cause. Thank ...
Star fruit link with estrogen? - Irritability and mood swings, withdrawal from social contacts, dependence on parents and doctors suspect wrist rather than promising complete pain relief although severe testicular swelling may be anxious with the second needle. However, the relative sensitivity of pax pax qq pax pax. And alterations in the pronephric field extends within the epithelia of the pax gene an essential but limited role in the, Chapter eighttherapeutic considerations predialysis interventions. It allows the detection of intracranial hemorrhage and of the existence of a coilcath catheter as the diffusion of co morbid medical problems such as achaete which confers on them as replacement therapy renal replacement therapy. After all, setting aside the goal of preventing cell death of another human being in the early rudiment and about % of overall effect is reduced greatly and completely absent the function of several experienced nephrologists who are decisive and organized in a reclining chair

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... while providing greater focus on the management of the end-stage renal disease population after a disaster which incapacitates ... Myoglobinuric renal failure is the classically described acute renal event occurring in disaster environments-commonly after an ... Austere renal replacement therapy (RRT) describes the provision of renal replacement therapy in any setting in which ... Renal Replacement Therapy in Austere Environments. Christina M. Yuan1 and Robert M. Perkins2. 1Nephrology Service, Department ...
... pathophysiology of renal disease and progression, clinical nephrology, dialysis, and transplantation. ... Renal replacement therapy (RRT) is an essential therapy in the setting of AKI and fluid overload. The decision to initiate RRT ... 3. AKI, Renal Angina, and the Why. The use of renal replacement therapy in pediatrics continues to blossom. It is uncertain ... "Estimating the impact of renal replacement therapy choice on outcome in severe acute renal failure," Clinical Nephrology, vol. ...
Renal replacement therapy explained. Renal replacement therapy comprises either transplantation or dialysis. Some people decide ... Transplant is the most common form of renal replacement therapy (approximately 54% of prevalent renal replacement therapy ... Approximately 8000 people a year start renal replacement therapy in the UK.1 Box 1 describes the options available for people ... Renal replacement therapy: summary of NICE guidance. BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k4303 (Published 19 October ...
Anticoagulation in continuous renal replacement therapy.. Abramson S1, Niles JL.. Author information. 1. Renal Division, ... Continuous renal replacement therapies (CRRTs) allow for gradual solute and fluid removal. In very sick patients with acute ... renal failure, they may be better tolerated than hemodialysis. The major drawback to CRRTs is the need for anticoagulation to ...
How can we achieve global equity in provision of renal replacement therapy?. Sarah L White a, Steven J Chadban b, Stephen Jan a ... GDP, gross domestic product; RRT, renal replacement therapy.a Data obtained as for Fig. 1.b Data show the prevalence of ... Worldwide, the number receiving renal replacement therapy (RRT) is estimated at more than 1.4 million,1 with incidence growing ... Aviles-Gomez R, Luquin-Arellano VH, Garcia-Garcia G, Ibarra-Hernandez M, Briseno-Renteria G. Is renal replacement therapy for ...
Intermittent hemodialysis; Prolonged intermittent renal replacement therapy; Continuous renal replacement therapy (CRRT); ... RENAL REPLACEMENT THERAPY. Indicate whether RRT therapy was medically indicated. If medically indicated, complete the rest of ... Record whether renal replacement therapy (RRT) was medically indicated for acute renal disease. If medically indicated, ... RENAL REPLACEMENT THERAPY. yes. 2. PRMEDIND. Was RRT medically indicated for acute kidney disease?. Indicate whether RRT ...
The instant invention relates to dialysis and in particular to continuous renal replacement therapy whereby an apparatus and ... continuous renal replacement therapy). In these procedures the patient is on dialysis twenty-four hours per day, seven days per ... Adjustable collection canister for continuous renal replacement therapy. ... The replacement or augmentation of the patients natural renal function can affect the balance of the body chemistry. In ...
A continuous renal replacement therapy (CRRT) device adapted to be worn on a portion of the body of a patient. The CRRT device ... Manns, Markus et al, "The acu-men: A New Device for Continuous Renal Replacement Therapy in Acute Renal Failure," Kidney ... A continuous renal replacement therapy (CRRT) device adapted to be worn on a portion of the body of a patient. The CRRT device ... 1. A continuous renal replacement therapy (CRRT) device comprising: means for enabling a patient to wear the entire CRRT device ...
... acute renal failure [ARF]). Most patients have been treated with hemodialysis, with the dialysis prescription varying in part ... Continuous renal replacement therapy in acute kidney injury (acute renal failure). Author. Thomas A Golper, MD. Thomas A Golper ... Ronco C. Continuous renal replacement therapies for the treatment of acute renal failure in intensive care patients. Clin ... USE OF CONTINUOUS RENAL REPLACEMENT THERAPY AND CHOICE OF DIALYSIS MODALITY. *Choice of continuous modality or intermittent ...
... the Global Continuous Renal Replacement Therapy (CRRT) Market is accounted for $0.78 billion in 2015 and is expected to reach ... In 2015, dialysate and replacement fluids segment has the dominant share in global Continuous Renal Replacement Therapy (CRRT) ... Global Continuous Renal Replacement Therapy (CRRT) Market Report. Press Release • Nov 15, 2016 02:05 EST ... Europe has the largest regional market for Continuous Renal Replacement Therapy (CRRT) due to approval of CRRT machine and anti ...
... Dialysis is a ... Material Detail: Renal Replacement Therapy: Hemodialysis vs Peritoneal Dialysis, with Animation - Medical Information ... You just viewed Renal Replacement Therapy:.... Please take a moment to rate this material. ... Disciplines with similar materials as Renal Replacement Therapy: Hemodialysis vs Peritoneal Dialysis, with Animation - Medical ...
... J Crit Care. 2009 Sep;24(3):394-400. doi: ... We reviewed our continuous renal replacement therapy (CRRT) experience to evaluate for factors associated with mortality as ... In addition, we report that duration of mechanical ventilation, PICU stay, hospitalization, and time to renal recovery were all ... FO and time to renal recovery (P = .0038). Greater %FO was also associated with significantly prolonged days of mechanical ...
... who had end-stage renal disease and were receiving renal replacement therapy. Fasting serum cholesterol (CHOL), triglyceride ( ... Fish Oil Treatment of Hyperlipidemia in Children and Adolescents Receiving Renal Replacement Therapy. Avner Goren, Alfred ... Fish Oil Treatment of Hyperlipidemia in Children and Adolescents Receiving Renal Replacement Therapy ... Fish Oil Treatment of Hyperlipidemia in Children and Adolescents Receiving Renal Replacement Therapy ...
Therapeutic Drug Monitoring in Neonatal HSV Infection on Continuous Renal Replacement Therapy. Takanori Funaki, Ippei Miyata, ... Therapeutic Drug Monitoring in Neonatal HSV Infection on Continuous Renal Replacement Therapy ... Therapeutic Drug Monitoring in Neonatal HSV Infection on Continuous Renal Replacement Therapy ... Therapeutic Drug Monitoring in Neonatal HSV Infection on Continuous Renal Replacement Therapy ...
Home › News › Pharma Industry News › Baxter to Acquire Continuous Renal Replacement Therapy Business from Edwards Lifesciences ... Baxter to Acquire Continuous Renal Replacement Therapy Business from Edwards Lifesciences. Print this page ... also known as Continuous Renal Replacement Therapy (CRRT). The transaction is expected to close in the third quarter of 2009, ... "As an experienced leader in dialysis therapies including CRRT, this acquisition represents an extension of our existing Renal ...
Referral for renal replacement therapy. Quality statement. People with acute kidney injury who meet the criteria for renal ... Proportion of people with acute kidney injury who meet the criteria for renal replacement therapy who are referred immediately ... People with acute kidney injury who need renal replacement therapy (such as dialysis) are referred immediately to specialist ... Healthcare professionals immediately refer people with acute kidney injury who meet the criteria for renal replacement therapy ...
Meropenem and continuous renal replacement therapy: in vitro permeability of 2 continuous renal replacement therapy membranes ... Pharmacokinetics of meropenem in patients with renal failure and patients receiving renal replacement therapy. Clin ... Minimum Inhibitory Concentration Septic Patient Meropenem Continuous Renal Replacement Therapy Patient Type These keywords were ... Bellomo R, Ronco C. Nomenclature for continuous renal replacement therapies. In: Ronco C, Bellomo R, editors. Critical care ...
"Renal Replacement Therapy" by people in Harvard Catalyst Profiles by year, and whether "Renal Replacement Therapy" was a major ... of withdrawal from renal replacement therapy among patients with acute kidney injury requiring renal replacement therapy. Clin ... When to stop renal replacement therapy in anticipation of renal recovery in AKI: The need for consensus guidelines. Semin Dial ... Vascular access for renal replacement therapy in acute kidney injury: Are nontunneled catheters the right choice? Semin Dial. ...
... mortality at 90 days between patients who were assigned to an early strategy for the initiation of renal-replacement therapy ... did not receive renal-replacement therapy. Criteria for emergency renal-replacement therapy were met in 17% of the patients in ... Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis N Engl J Med. 2018 Oct 11;379(15):1431-1442 ... Although renal-replacement therapy is the standard of care for severe acute kidney injury, the ideal time for initiation ...
... is a frequent complication of all renal replacement therapy (RRT) modalities commonly used in the intensive care unit. HIRRT is ... Hemodynamic instability related to renal replacement therapy (HIRRT) ... CRRT continuous renal replacement therapy, HD, RRT renal replacement therapy, hemodialysis, SLED sustained low-efficiency ... CRRT continuous renal replacement therapy, HIRRT hemodynamic instability related to renal replacement therapy, MAP mean ...
Renal replacement therapy (RRT) is therapy that replaces the normal blood-filtering function of the kidneys. It is used when ... Renal replacement therapy also includes kidney transplantation, which is the ultimate form of replacement in that the old ... Continuous renal replacement therapy (CRRT) is a form of dyalisis therapy used in critical care settings. The benefit of CRRT ... Renal replacement therapy includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration, which ...
... data of patients hospitalized on intensive care unit from 2009 to 2011 and had to undergo one sort of renal replacement therapy ... data of patients hospitalized on intensive care unit from 2009 to 2011 and had to undergo one sort of renal replacement therapy ...
... and continuous renal replacement therapy. Host Pamela M. Peeke, MD, MPH, FACP, FACSM , is joined by Michael J. Connor Jr, MD, ... The increase in acute kidney injury in COVID-19 patients is resulting in more utilization of renal replacement therapy (RRT) ... Categories: Disaster, Renal, Content Type: Podcasts, continuous renal replacement therapy Coronavirus COVID-19 renal ... therapies such as continuous renal replacement therapy or a related mechanism called prolonged intermittent renal replacement ...
Intermittent versus continuous renal replacement therapy for acute renal failure in adults ... Is continuous renal replacement therapy beneficial for people with rhabdomyolysis?. Rhabdomyolysis is a potentially life- ... Intensity of continuous renal replacement therapy for acute kidney injury. *Is treatment with corticosteroids beneficial and ... There is some evidence to suggest that continuous renal replacement therapy (CRRT) may provide benefits for people with ...
Survival of Indigenous Australians receiving renal replacement therapy: closing the gap?. Paul D Lawton, Joan Cunningham, ... Renal replacement therapy in rural and urban Australia. Nephrol Dial Transplant 2012; 27: 2069-2076. ... Survival of patients from South Asian and Black populations starting renal replacement therapy in England and Wales. Nephrol ... Objectives: To compare mortality rates for Indigenous and non-Indigenous Australians commencing renal replacement therapy (RRT ...
Renal replacement therapy for diabetic end-stage renal disease: data from 10 registries in Europe (1991-2000). Kidney Int 2005; ... Survival of Patients With Type 1 Diabetes Receiving Renal Replacement Therapy in 1980-2007. Mikko Haapio, Jaakko Helve, Per- ... Data on the survival of patients receiving renal replacement therapy (RRT) are, however, limited. We investigated whether ... registries showed a decrease in the mortality rates of patients with type 1 diabetes receiving renal replacement therapy (RRT) ...
... as part of supportive therapy in the pediatric intensive care unit. While many centers employ no anticoagulation for fear of ... Pediatric liver failure patients frequently develop multiple organ failure and require continuous renal replacement therapy ( ... 4. Agarwal B, Shaw S, Shankar Hari M, Burroughs AK, Davenport A. Continuous renal replacement therapy (CRRT) in patients with ... Outcomes of Continuous Renal Replacement Therapy With Regional Citrate Anticoagulation in Small Children After Cardiac Surgery ...
Renal replacement therapy (RRT) is a blood purification technique used to treat the most severe forms of AKI. The optimal time ... Timing of initiation of renal replacement therapy for acute kidney injury. What is the issue? ... Renal replacement therapy (RRT) is a blood purification technique that enables removal of excess water and toxins. RRT involves ... This review complements another Cochrane review by the same authors: Intensity of continuous renal replacement therapy for ...
Peritoneal Dialysis Renal Replacement Therapy Acute Kidney Injury Continuous Renal Replacement Therapy Fresh Freeze Plasma ... and if their removal is not addressed by either renal recovery or the initiation of artificial renal replacement therapy, the ... Bellomo R. Do we know the optimal dose for renal replacement therapy in the intensive care unit? Kidney Int. 2006;70:1202-1204. ... Unfortunately, AKI requiring renal replacement therapy (RRT) is relatively common in critically ill patients treated in the ...
Patients with acute kidney injury with volume overload unresponsive to medication therapy =Required renal replacement therapy ( ... BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy. The safety and scientific ... BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy ... Impedance Analysis Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy;Which One ...
  • In this paper we briefly review the epidemiology and outcomes of patients with dialysis-requiring AKI after such events, while providing greater focus on the management of the end-stage renal disease population after a disaster which incapacitates a pre-existing nephrologic infrastructure (if it existed at all). (hindawi.com)
  • Austere" dialysis, as such, is defined as the provision of renal replacement therapy in any setting in which traditional, first-world therapies and resources are limited, incapacitated, or nonexistent. (hindawi.com)
  • Comparison of peritoneal dialysis (PD), intermittent hemodialysis (IHD), and continuous renal replacement therapies (CRRT). (hindawi.com)
  • Peritoneal dialysis (PD) is the most widely available form of renal replacement therapy used in children. (hindawi.com)
  • Renal replacement therapy comprises either transplantation or dialysis. (bmj.com)
  • See 'Renal replacement therapy (dialysis) in acute kidney injury: Metabolic and hemodynamic considerations' . (uptodate.com)
  • Dialysis is a therapy that artificially removes wastes from the blood of patients whose kidneys can no longer perform this function adequately. (merlot.org)
  • As an experienced leader in dialysis therapies including CRRT, this acquisition represents an extension of our existing Renal business, and demonstrates our commitment to save and sustain the lives of patients with acute kidney injuries," said Bruce McGillivray, corporate vice president and president of Baxter's Renal business. (drugs.com)
  • People with acute kidney injury who need renal replacement therapy (such as dialysis) are referred immediately to specialist services so that delays in having the treatment are avoided. (nice.org.uk)
  • Hemodynamic instability related to renal replacement therapy (HIRRT) is a complication of all RRT modalities commonly used in the ICU, including intermittent hemodialysis (HD), sustained low-efficiency dialysis (SLED) and continuous renal replacement therapy (CRRT). (springer.com)
  • Renal replacement therapy includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration, which are various ways of filtration of blood with or without machines. (wikipedia.org)
  • Early dialysis (and, if indicated, early renal transplant) in acute kidney failure usually brings more favorable outcomes. (wikipedia.org)
  • CONCLUSIONS Survival of patients with type 1 diabetes and end-stage renal disease has improved since the 1980s despite a conspicuous increase in the age of patients who start RRT, suggesting not only true progress in dialysis therapy and overall treatment of patients with end-stage renal disease but possibly also improved management of diabetes. (diabetesjournals.org)
  • Our incident cohort study included all patients with type 1 diabetes as the cause of renal failure who had started chronic RRT (hemodialysis, peritoneal dialysis, or kidney transplantation) in Finland from 1 January 1980 to 31 December 2005 ( n = 1,604). (diabetesjournals.org)
  • 3 When a decision is made that artificial renal replacement therapy is needed, the physician has a variety of techniques at his/her disposal: intermittent hemodialysis (IHD), continuous renal replacement therapy (CCRT), slow extended daily dialysis (SLEDD), and peritoneal dialysis, each with its technical variations. (springer.com)
  • Replacement of renal function by dialysis. (springer.com)
  • Bellomo R, Ronco C. Adequacy of dialysis in the acute renal failure of the critically ill: the case for continuous therapies. (springer.com)
  • People with advanced chronic renal failure (CRF), kidney failure, who have progressed to end-stage renal disease (ESRD) usually require dialysis. (healthcommunities.com)
  • People with advanced chronic renal failure are advised to prepare for dialysis before it is needed, instead of having to rely on it in a crisis. (healthcommunities.com)
  • Pericarditis (inflammation of the sac that surrounds the heart) is associated with end-stage renal disease (ESRD) and indicates the need for dialysis. (healthcommunities.com)
  • Secular trends in end-stage kidney disease requiring renal replacement therapy in Japan: Japanese Society of Dialysis Therapy Registry data from 19. (nih.gov)
  • Secular trends in end-stage kidney disease requiring renal replacement therapy in Japan: Japanese Society of Dialysis Therapy Registry data from 1983 to 2016. (nih.gov)
  • Hepatitis C virus infection is a frequent clinical problem in patients on dialysis and renal transplant recipients. (fmshk.com.hk)
  • Repeated blood transfusions and a long duration of dialysis are major risk factors for hepatitis C virus infection among patients with renal failure. (fmshk.com.hk)
  • Dialysis patients with hepatitis C virus infection, especially those with a potential for kidney transplantation, should be considered for treatment with interferon, because the risk of interferon in inducing renal allograft dysfunction is too high to justify its routine use in renal allograft recipients. (fmshk.com.hk)
  • These analyses of the effect of angiotensin II on AKI patients requiring dialysis in the ATHOS-3 study demonstrated angiotensin II is a promising therapy to address this unmet need. (globenewswire.com)
  • This combination of the technological and the biological allows for the elimination of pumps, tubes, dialysis, and immunosuppressive drugs for a permanent solution to renal failure. (homedialysis.org)
  • Incremental improvements to existing dialysis therapies are long overdue. (homedialysis.org)
  • Seven patients required chronic renal dialysis. (frontiersin.org)
  • Results: The prevalence of dyslipidaemia was 85.1% in peritoneal dialysis (PD) patients, 76.1% in haemodialysis (HD) patients and 55.5% among renal allograft recipients. (uzh.ch)
  • 2008). Continuous Renal Replacement Therapy (CRRT) as a recently developed blood purification modality, therapy continues until return of renal functions or patient is transitioned to intermittent dialysis, functions similar to IHD where patient blood is divided into thousands of straw like semi permeable membranes in a dialyzer and uses principles of diffusion, convection and adhesion (Acierno, 2011). (thefreelibrary.com)
  • Commercially available dialysis solution (Prismasol BO (b)) was used as a dialysate and replacement fluid to promote the process of diffusion and convection, effluent dose rate was set at 30-40ml/kg/hr. (thefreelibrary.com)
  • Renal replacement therapy can be classified into peritoneal dialysis, intermittent hemodialysis, and continuous renal replacement therapy. (medgadget.com)
  • The growing number of acute kidney injury cases and the advent of technological advancement in the field of pediatric, such as Cardio-Renal Pediatric Dialysis Emergency Machine (CARPEDIUM) for the treatment of acute kidney injury in kids and children are some of the other major factor propelling the market growth. (medgadget.com)
  • We illustrate the use of this framework by applying it to three key end-stage renal disease decisions in older patients with varying life expectancy: choice of dialysis modality, choice of vascular access for hemodialysis, and referral for kidney transplantation. (pubmedcentralcanada.ca)
  • To assess the role of advanced age on survival and dialysis dependency after initiation of renal replacement therapy for acute kidney injury. (ovid.com)
  • BACKGROUND: Different kidney replacement therapy modalities are available to manage end-stage kidney disease, such as home-based dialysis, in-center hemodialysis, and kidney transplantation. (ugent.be)
  • Dialysis-dependent acute kidney injury (AKI) can be treated using continuous (CRRT) or intermittent renal replacement therapies (IRRT). (egms.de)
  • Our main study objective was to better understand patient satisfaction with the scope and quality of dialysis education received before beginning renal replacement therapy (RRT) as well as with their current therapy. (asnjournals.org)
  • Usually, most patients will be managed completely by the renal team, either because the patient requires dialysis or because conservative but specialised care is appropriate. (rcpe.ac.uk)
  • Methods Patients ≥75 years of age at the onset of RRT in 2010-2013 from 29 national or regional registries providing data to the European Renal Association-European Dialysis and Transplant Association Registry were included. (deepdyve.com)
  • Among elderly patients with comorbidities, dialysis may not provide a survival advantage or improve health-related quality of life over conservative management of end-stage renal disease (ESRD) [7-9], so careful selection of patients who are likely to benefit from RRT is essential. (deepdyve.com)
  • Incidence of AN in former Czechoslovakia was investigated in patients commencing renal replacement therapy in 24 (1/3 of all) dialysis centres from 1 January to 31 December 1992. (oup.com)
  • Dialysis is a treatment for patients with end-stage renal failure (ESRF) whereby toxins and excess fluid are removed from the body by filtration devices either in the form of peritoneal or haemodialysis. (medicaleducationleeds.com)
  • where these treatments can be planned early with appropriate support and counselling from specialist physicians, dialysis nurses, dieticians and renal psychologists if necessary. (medicaleducationleeds.com)
  • To evaluate the HRQOL of children with ESRD according to the modality of renal replacement therapy: Hemodialysis (HD), Peritoneal Dialysis (PD), and Renal Transplant (RT). (longdom.org)
  • 4. MECHANISMS  2 fundamental processes underlie continuous renal replacement therapy - diffusion and convection Diffusion / dialysis-  movement of solutes from compartment in which they are in high concentration to 1 in which they are in lower concentration - along an electrochemical gradient. (slideshare.net)
  • Since 2015, the Committee for International Communication on Academic Research of the Japanese Society for Dialysis Therapy has held its Asian symposium during the society's Annual Congress to discuss the pres. (biomedcentral.com)
  • Renal replacement therapy include alternating hemodialysis, peritoneal dialysis, continuous renal replacement therapies (CRRTs), and hybrid therapies such as prolonged alternating renal replacement therapies (PIRRTs), which are prolonged alternating dialysis. (theinsightpartners.com)
  • Continuous renal replacement therapy (CRRT) is a dialysis modality used to treat severely sick, hospitalized patients admitted in the intensive care unit who generally develops Acute Kidney Injury (AKI). (theinsightpartners.com)
  • Dialysis substitutes the natural work of the kidneys, so it is also known as renal replacement therapy (RRT). (medicalnewstoday.com)
  • Percutaneously placed intraperitoneal catheters or permanent Tenckhoff catheters are used even in neonates, and catheter placement is relatively simple compared to the vascular access required for intermittent hemodialysis (IHD) or continuous renal replacement therapy (CRRT). (hindawi.com)
  • In very sick patients with acute renal failure, they may be better tolerated than hemodialysis. (nih.gov)
  • Renal replacement therapy (RRT), usually in the form of hemodialysis, is frequently needed to manage patients with severe AKI. (ualberta.ca)
  • Daily 12-hour sustained low-efficiency hemodialysis (SLED) for the treatment of critically ill patients with acute renal failure: initial experience. (springer.com)
  • Traditional intermittent hemodialysis (IHD) therapies use large amounts of dialysate that are generated from a purified water system. (mspca.org)
  • Continuous renal replacement therapy (CVVHDF) was performed with Gambro Prismaflex (a) hemodialysis machine as per the standard protocols. (thefreelibrary.com)
  • Continuous renal replacement includes hemodialysis, hemofiltration or a combination of both. (medgadget.com)
  • It differs from the conventional renal replacement therapies whereas intermittent hemodialysis last for six hours and continuous renal replacement therapy lasts for 24 hours. (medgadget.com)
  • continuous renal replacement therapy hemodialysis or hemofiltration done 24 hours a day for an extended period, usually in a critically ill patient. (thefreedictionary.com)
  • CRRT is an effective alternative renal replacement therapy for removal of wastes and excess plasma water in critically ill patients-especially those who are hypotensive and can't tolerate the rapid fluid and electrolyte shifts of hemodialysis. (americannursetoday.com)
  • The four types of CRRT therapy are continuous venovenous hemodialysis, continuous venovenous hemo-filtration, continuous venovenous hemo-diafiltration, and slow continuous ultrafiltration. (americannursetoday.com)
  • In therapies segment, the market is divided into SCUF (slow continuous ultra-filtration), CVVH (continuous venovenous hemofiltration), CVVHD (continuous venovenous hemodialysis) and CVVHDF (continuous venovenous hemodiafiltration). (marketresearch.com)
  • Continuous veno-venous hemodialysis therapy has technical advantages and is mostly suitable for geriatric population. (gminsights.com)
  • Moreover it appears that the hemodynamic changes that occur during hemodialysis (hypotension) may worsen the pre-existing renal injury by increasing the ischemic insult. (slideshare.net)
  • Calcium carbonate is a first-line therapy for hyperphosphatemia in hemodialysis patients but is associated with progressive coronary and aortic calcification. (biomedcentral.com)
  • The Prospective Pediatric Continuous Renal Replacement Therapy (ppCRRT) registry, a comprehensive and collaborative registry composed of thirteen select pediatric referral centers, was established in 2000 to prospectively evaluate clinical aspects of CRRT and recently reported an overall mortality of 43.1% for critically ill children placed on RRT [ 7 ]. (hindawi.com)
  • A continuous renal replacement therapy (CRRT) device adapted to be worn on a portion of the body of a patient. (freepatentsonline.com)
  • An alternative approach is the use of continuous renal replacement therapy (CRRT). (uptodate.com)
  • However, high complexity & procedural costs of CRRT therapy, inconsistent reimbursement scenario in European countries and lack of trained ICU nurses are the factors restraining the market growth. (mynewsdesk.com)
  • In 2015, dialysate and replacement fluids segment has the dominant share in global Continuous Renal Replacement Therapy (CRRT) products market and is expected to continue its dominance throughout the forecast period. (mynewsdesk.com)
  • The dominance is due to its higher demand during CRRT procedure, and improvisation and commercialization of advanced renal replacement solutions. (mynewsdesk.com)
  • Europe has the largest regional market for Continuous Renal Replacement Therapy (CRRT) due to approval of CRRT machine and anti-coagulants for multiple applications, rapidly increasing aging population and increasing prevalence of AKI patients. (mynewsdesk.com)
  • We reviewed our continuous renal replacement therapy (CRRT) experience to evaluate for factors associated with mortality as well as secondary outcomes. (nih.gov)
  • DEERFIELD, Ill.--(BUSINESS WIRE)--Jun 23, 2009 - Baxter International Inc. (NYSE:BAX) announced today a definitive agreement with Edwards Lifesciences Corporation (NYSE:EW) under which Baxter will acquire certain assets related to Edwards' hemofiltration product line, also known as Continuous Renal Replacement Therapy (CRRT). (drugs.com)
  • Meropenem is a carbapenem antibacterial frequently prescribed for the treatment of severe infections in critically ill patients, including those receiving continuous renal replacement therapy (CRRT). (springer.com)
  • The increase in acute kidney injury in COVID-19 patients is resulting in more utilization of renal replacement therapy (RRT) and continuous renal replacement therapy (CRRT). (sccm.org)
  • There is some evidence to suggest that continuous renal replacement therapy (CRRT) may provide benefits for people with rhabdomyolysis. (cochrane.org)
  • There was insufficient evidence to discern any likely benefits of CRRT over conventional therapy for people with rhabdomyolysis and prevention of rhabdomyolysis-induced AKI. (cochrane.org)
  • Studies have indicated that continuous renal replacement therapy (CRRT) may provide benefits for people with rhabdomyolysis by removing potentially damaging myoglobin and stabilising haemodynamic and metabolic status. (cochrane.org)
  • Pediatric liver failure patients frequently develop multiple organ failure and require continuous renal replacement therapy (CRRT) as part of supportive therapy in the pediatric intensive care unit. (plos.org)
  • Pediatric acute and acute-on-chronic liver failure can lead to multiple organ failure and associated acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) [ 1 ]. (plos.org)
  • The aim of this study is to determine the Pharmacokinetics/Pharmacodynamics(PK/PD) of tigecycline in critical ill patients undergoing continuous renal replacement therapy(CRRT(and examine whether the dosage needs adjustment. (clinicaltrials.gov)
  • receiving CRRT with renal insufficiency or not receiving CRRT with normal renal function. (clinicaltrials.gov)
  • Conventional continuous renal replacement therapy (CRRT) is based on convective therapies but CRRT machines, such as the Prismaflex®, also allow for diffusive clearance or a combination of both diffusive and convective clearance (hemodiafiltration). (mspca.org)
  • Over-hydration has been shown to be an independent predictor of death in people (CRRT vet clinics) and the human literature documents the negative effect of aggressive fluid therapy on survival, length of hospital stays, and oxygenation status. (mspca.org)
  • Indications for CRRT are refractory azotemia (BUN level [greater than or equal to]90mg/dl, creatinine level [greater than or equal to]5 mg/dl), interactable uremia, hyperkalemia, fluid overload, severe metabolic acidosis, pre-operative conditioning for renal transplantation, delayed graft function, graft rejection and acute on CRF (Elliott, 2000). (thefreelibrary.com)
  • Indications of extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) are expanding to poisoning cases. (koreamed.org)
  • The PrisMax system and integrated TherMax blood warmer is Baxter's next-generation platform for continuous renal replacement therapy (CRRT) and therapeutic plasma exchange (TPE). (mpo-mag.com)
  • Continuous renal replacement therapies (CRRT) are often used to manage complex acid-base problems in critically ill patients. (biomedsearch.com)
  • The use of CRRT as a customized therapy for acid-base disorders is discussed, allowing an integration of both physiological and technical concepts. (biomedsearch.com)
  • The therapy most commonly used is continuous renal replacement therapy (CRRT). (americannursetoday.com)
  • Continuous renal replacement therapy (CRRT) has become the standard of care for patients in an intensive care unit (ICU) who experience acute kidney injury (AKI), fluid overload, or electrolyte or acid-base derangements ( 1 ). (asm.org)
  • Volume of distribution ( V d ) and clearance (Cl) are pharmacokinetic (PK) parameters affected to various degrees in CRRT patients depending on patient size, residual renal function, and modality of CRRT clearance delivered, among other factors ( 2 , 3 ). (asm.org)
  • The global continuous renal replacement therapy (CRRT) market is growing at the CAGR of 7.69% and will contribute $1290 million till 2022. (marketresearch.com)
  • Asia Pacific is the fastest growing global continuous renal replacement therapy (CRRT) market, in terms of revenue in forecast period. (marketresearch.com)
  • Increasing geriatric population, rising healthcare infrastructure are the major reasons which boost the Asia Pacific region's growth in the global continuous renal replacement therapy (CRRT) market. (marketresearch.com)
  • Europe is a dominating region in global continuous renal replacement therapy (CRRT) market. (marketresearch.com)
  • North American region is also a growing market for global continuous renal replacement therapy (CRRT) market. (marketresearch.com)
  • Global continuous renal replacement therapy (CRRT) market is segmented into therapies, products and regional outlook. (marketresearch.com)
  • CVVH (continuous venovenous hemofiltration) was a leader in therapies segment of global continuous renal replacement therapy (CRRT) market in 2015. (marketresearch.com)
  • Dialysate dominates the global continuous renal replacement therapy (CRRT) market in product segment and this dominance is expected to continue in forecast period. (marketresearch.com)
  • The factors like high cost of these systems, as well as the overall procedure involving continuous renal replacement therapy systems and unfavorable medical reimbursement policies are especially affecting the large-scale adoption of continuous renal replacement therapy systems in developing and under-developed countries, which hinders the growth of global continuous renal replacement therapy (CRRT) market. (marketresearch.com)
  • The country research report on Ireland continuous renal replacement therapy (CRRT) market is a customer intelligence and competitive study of the Ireland market. (marketresearch.com)
  • Also, factors that are driving and restraining the continuous renal replacement therapy (CRRT) market are highlighted in the study. (marketresearch.com)
  • The companies and dealers/distributors profiled in the report include manufacturers & suppliers of continuous renal replacement therapy (CRRT) market in Ireland. (marketresearch.com)
  • The report on Ireland continuous renal replacement therapy (CRRT) market provides a detailed analysis of segments in the market based on product, therapy, modality, and end-user. (marketresearch.com)
  • 1) What is the market size of continuous renal replacement therapy (CRRT) market in Ireland? (marketresearch.com)
  • 2) What are the factors that affect the growth in continuous renal replacement therapy (CRRT) market over the forecast period? (marketresearch.com)
  • 4) What are the opportunities in Ireland continuous renal replacement therapy (CRRT) market? (marketresearch.com)
  • 5) What are the modes of entering Ireland continuous renal replacement therapy (CRRT) market? (marketresearch.com)
  • This study assessed differences between CRRT and IRRT regarding important clinical outcomes (such as mortality and renal recovery) and cost-effectiveness. (egms.de)
  • Findings show a higher rate of renal recovery among survivors who initially received CRRT as compared with IRRT. (egms.de)
  • Findings of the conducted assessment show that initial CRRT is associated with higher rates of renal recovery. (egms.de)
  • Use of a nurse emergency team for patients treated with continuous renal replacement therapy (CRRT) also has potential to reduce adverse outcomes with CRRT, where staff may lack experience or find troubleshooting CRRT difficult in an ICU with many critically ill patients in their care. (edu.au)
  • We identified 18 potential quality indicators (QIs) of continuous renal replacement therapy (CRRT) care in the current literature. (springermedizin.de)
  • Renal replacement therapy is increasingly utilized in the intensive care unit (ICU), of which continuous renal replacement therapy (CRRT) is most common. (springermedizin.de)
  • The global continuous renal replacement therapy (CRRT) market size was valued at USD 986.4 million in 2019 and is projected to reach USD 1,811.5 million by 2027, exhibiti. (fortunebusinessinsights.com)
  • The aim of this study was to describe the efficacy, security and viability of an anticoagulation system with continuous infusion of unfractionated heparin (UFH) versus one without any type of anticoagulant using 0.9% physiological saline washings, in critically ill patients with continuous renal replacement therapy (CRRT) and different risks of bleeding" Sanz Ganuza et al (2017). (ivteam.com)
  • Continuous renal replacement therapy (CRRT) is a common intervention to maintain physiologic plasma composition when acute kidney injury (AKI) complicates critical illness. (biomedcentral.com)
  • To study the effect of Continuous Renal Replacement Therapy (CRRT) on serum BNP, IL-34, hs-CRP and blood gas analysis index in acute myocardial infarction patients with cardiac insufficiency. (alliedacademies.org)
  • CRRT was initiated in these patients because of the failure of medical drug therapy. (alliedacademies.org)
  • Objective: To determine the influence of vascular access site on continuous renal replacement therapy (CRRT) filter survival. (monash.edu)
  • Therefore, elderly population suffering from renal failure is recommended long term continuous renal replacement therapy that makes use of advanced CRRT systems stimulating the industry growth. (gminsights.com)
  • However, high cost associated with CRRT may restrain its demand in emerging economies thereby, hampering the continuous renal replacement market growth to some extent. (gminsights.com)
  • On the basis of simulations, a strategy of an extended-interval high loading dose of amikacin (25 mg/kg every 48 h) associated with therapeutic drug monitoring (TDM) should be the preferred approach for aminoglycoside treatment in critically ill patients receiving continuous renal replacement therapy (CRRT). (edu.au)
  • The continuous renal replacement therapy (CRRT) market is expected to grow dramatically due to the key reasons such as rising demand for the consumables which includes fluids, hemofilters, charcoal filters and others consumables in CRRT procedures. (theinsightpartners.com)
  • The "Global Continuous Renal Replacement Therapy (CRRT) Market Analysis to 2027" is a specialized and in-depth study of the medical device industry with a focus on the global market trend. (theinsightpartners.com)
  • The report aims to provide an overview of global continuous renal replacement therapy (CRRT) market with detailed market segmentation by product, mode and geography. (theinsightpartners.com)
  • The global continuous renal replacement therapy (CRRT) market is expected to witness high growth during the forecast period. (theinsightpartners.com)
  • The segmentation of the continuous renal replacement therapy (CRRT) market is classified as product, and mode. (theinsightpartners.com)
  • It provides overview and forecast of the global continuous renal replacement therapy (CRRT) market based on products, and mode. (theinsightpartners.com)
  • North America accounts the largest market for the continuous renal replacement therapy (CRRT) followed by Europe and the Asia Pacific is expected to be the fastest growing market. (theinsightpartners.com)
  • The report also includes the profiles of key continuous renal replacement therapy (CRRT) companies along with their SWOT analysis and market strategies. (theinsightpartners.com)
  • Prompt treatment offers potential benefits that include preventing further deterioration of renal function, improving chances of renal recovery, shorter hospital stays, lower mortality and better long‑term outcomes. (nice.org.uk)
  • Among patients with septic shock who had severe acute kidney injury, there was no significant difference in overall mortality at 90 days between patients who were assigned to an early strategy for the initiation of renal-replacement therapy and those who were assigned to a delayed strategy. (nih.gov)
  • To compare mortality rates for Indigenous and non-Indigenous Australians commencing renal replacement therapy (RRT) over time and by categories of remoteness of place of residence. (mja.com.au)
  • A European study with data from 10 national registries showed a decrease in the mortality rates of patients with type 1 diabetes receiving renal replacement therapy (RRT) during the time period 1991-2000 ( 7 ). (diabetesjournals.org)
  • Renal failure is an independent predictor of mortality in intensive care unit (ICU) patients, despite the technological advances in the management of critically ill patients and the new techniques of renal replacement therapy (RRT). (scielo.br)
  • 1 ) The mortality of renal failure remains high, especially when associated with the dysfunction of other organs, such as acute lung injury (ALI). (scielo.br)
  • Our aim is finding prognostic factors for hospital mortality in patients with cancer with ARF requiring renal replacement therapy (RRT). (frontiersin.org)
  • Optimally, education could reduce the 'urgent starts' that lead to increased morbidity, mortality, and costs as therapy is initiated ( 7 , 8 ). (asnjournals.org)
  • BACKGROUND: Patients who die within 90 days of commencing renal replacement therapy (RRT) may be recorded by some centres and not others, and hence data on mortality and survival may not be comparable. (kuleuven.be)
  • Does a medical management program for CKD patients postpone renal replacement therapy and mortality? (biomedcentral.com)
  • This study aimed to investigate the effect of two competing clinical strategies of treatments under nephrologists' supervision compared with no treatment on the frequency of the need to start renal replacement therapy (RRT) and mortality in CKD patients. (biomedcentral.com)
  • Declining comorbidity-adjusted mortality rates in English patients receiving maintenance renal replacement therapy. (ox.ac.uk)
  • We aimed to compare long-term mortality trends in end-stage renal disease versus general population controls after accounting for differences in age, sex and comorbidity. (ox.ac.uk)
  • After accounting for age, sex and comorbidity differences, standardized three-year all-cause mortality rates in treated patients with end-stage renal disease between 1970 and 2011 fell by about one-half (relative decline 51%, 95% confidence interval 41-60%) steeper than the one-third decline (34%, 31-36%) observed in the general population. (ox.ac.uk)
  • Pediatric index of mortality (PIM), pediatric risk of mortality score (PRISM), multi-organ failure score, serum lactate levels, blood pressure, vasoactive drugs, renal function and characteristics of renal replacement therapy were analyzed. (semanticscholar.org)
  • Outcomes assessed through demography-matched scleroderma-positive/scleroderma-negative comparisons included recovery of kidney function, mortality, listing for transplant, renal transplantations, and graft failure. (readbyqxmd.com)
  • Continuous renal replacement therapy is associated with reduced serum ammonia levels and mortality in acute liver failure. (semanticscholar.org)
  • Diabetes is the most important cause of end-stage renal disease (ESRD) in industrialized countries, reflecting the rapidly growing number of patients with adult-onset diabetes ( 1 , 2 ). (diabetesjournals.org)
  • KHI, a public-private partnership between the American Society for Nephrology (ASN) and the U.S. Food and Drug Administration (FDA), was created in September 2012 to focus on promoting the development of safe and effective therapies for kidney disease and improving the lives of millions of kidney patients with end stage renal disease (ESRD). (homedialysis.org)
  • Background: Information on lipid abnormalities in end-stage renal disease (ESRD) mainly originates from adult patients and small paediatric studies. (uzh.ch)
  • There is substantial variation in the type and intensity of care provided to older patients with end-stage renal disease (ESRD), 1 stemming from uncertainty about the benefits and harms of ESRD treatment strategies in this growing population. (pubmedcentralcanada.ca)
  • Several factors may influence the choice of method, including patients' clinical health at the beginning of ESRD therapy, physician and patient preferences, geographic location ( 2 ), and individual characteristics. (asnjournals.org)
  • Background and objectives This study was undertaken by the American Association of Kidney Patients (AAKP) to better understand ESRD patients' satisfaction with their current renal replacement therapy (RRT) and the education they received before initiating therapy. (asnjournals.org)
  • elderly, ESRD, Europe, incidence, renal replacement therapy INTRODUCTION The European population is ageing and the proportion of individuals ≥80 years of age has increased from 3.9% in 2004 to 5.1% in 2014 [1]. (deepdyve.com)
  • The incidence and prevalence of end-stage renal disease (ESRD), which is not restricted to the developed world, is escalating. (biomedcentral.com)
  • End-Stage Renal Disease (ESRD) is a major health problem. (longdom.org)
  • Although the risk of developing cancer is reported to be higher in patients with end-stage renal disease (ESRD) than. (biomedcentral.com)
  • However, few data are available on the long-term outcome of patients with end-stage renal disease (ESRD) secondary to SLE who are managed by different types of RRTs. (kjim.org)
  • Lupus nephritis develops in 60% of patients with systemic lupus erythematosus (SLE), and 20% of patients with lupus nephritis develop end-stage renal disease (ESRD) within 10 years of disease onset [ 1 ]. (kjim.org)
  • Although renal involvement in SLE is frequent and important, patients with ESRD secondary to SLE are relatively uncommon. (kjim.org)
  • Renal replacement therapy also includes kidney transplantation, which is the ultimate form of replacement in that the old kidney is replaced by a donor kidney. (wikipedia.org)
  • In the majority of patients, however, the adverse effect of hepatitis C virus infection on survival may not be evident in the first decade after renal transplantation. (fmshk.com.hk)
  • Hepatitis C virus-positive patients with renal failure should not be excluded from kidney transplantation, but should be assessed individually with regard to the severity of liver disease before transplantation. (fmshk.com.hk)
  • Prospective studies were included that examined coronary artery calcification with two or more multislice computed tomography scans ≥6 months apart in patients 18-75 years old receiving any renal replacement therapy, including kidney transplantation. (uu.nl)
  • Results: We identified 29 eligible studies that assessed coronary artery calcification progression in end-stage renal disease patients, of which 19 studies evaluated haemodialysis and 8 kidney transplantation. (uu.nl)
  • The present 12-months, multi-center, investigator-driven, prospective, randomized study was designed to assess whether conversion from tacrolimus to cyclosporine A can reverse PTDM after renal transplantation. (readbyqxmd.com)
  • There are complex risk-benefit tradeoffs with different transplantation strategies for end-stage liver disease patients on renal support. (elsevier.com)
  • Using a Markov discrete-time state transition model, we compared survival for this group with 3 strategies: simultaneous liver-kidney (SLK) transplantation, liver transplantation alone (LTA) followed by immediate kidney transplantation if renal function did not recover, and LTA followed by placement on the kidney transplant wait list. (elsevier.com)
  • When uncertainty was considered, the results indicated that the waiting time and renal recovery affected conclusions about survival after SLK transplantation and liver transplantation, respectively. (elsevier.com)
  • The subgroups with the longest durations of pretransplant renal replacement therapy and highest MELD scores had the largest absolute increases in survival with SLK transplantation versus sequential transplantation. (elsevier.com)
  • In conclusion, the findings demonstrate the inherent tension in choices about the use of available kidneys and suggest that performing liver transplantation and using renal transplantation only for those who fail to recover their native renal function could free up available donor kidneys. (elsevier.com)
  • The degree of renal failure must be estimated, disturbancies in the acid-base and calcium-phosphate balance corrected, the general state of the patient as regards other diabetic complications evaluated and the appropriate form of renal replacement therapy chosen and instituted. (springer.com)
  • Simultaneously, the number of patients on renal replacement therapy (RRT) ≥75 years of age has nearly doubled, comprising 30% of all patients entering RRT in Europe. (deepdyve.com)
  • Continuous Arterio-venous Hemofiltration in a Wearable Device to Treat End-stage Renal Disease," Trans Am Soc Artif Intern Organs, vol. (freepatentsonline.com)
  • Effect of filtration volume of continuous venovenous hemofiltration in the treatment of patients with acute renal failure in intensive care units. (semanticscholar.org)
  • Continuous veno-venous hemofiltration (CVVH) segment of continuous renal replacement therapy market held around 20.5% revenue share in 2018. (gminsights.com)
  • COUNTERPOINT: Should Continuous Venovenous Hemofiltration Always Be the Preferred Mode of Renal Replacement Therapy for the Patient With Acute Brain Injury? (semanticscholar.org)
  • Renal replacement therapy (RRT) began in 1977 with the use of continuous arteriovenous hemofiltration [Kramer P et al. (openanesthesia.org)
  • Myoglobinuric renal failure is the classically described acute renal event occurring in disaster environments-commonly after an earthquake-which most tests the ingenuity and flexibility of local and regional nephrology resources. (hindawi.com)
  • Therefore, 128 end-stage renal patients were selected from the hospital outpatient nephrology case management database. (clinicaltrials.gov)
  • Altogether, this work shows two ways of developing 3D renal cell models to study kidney physiology, pharmacology and pathology, and providing novel solutions within the regenerative nephrology field. (uu.nl)
  • Nephrology Now » Blog Archive » Derivation and Validation of a Simplified Predictive Index for Renal Replacement Therapy After Cardiac Surgery. (nephrologynow.com)
  • It is unclear which patients are appropriate for therapy, which modalities should be used, what the triggers are for initiation, what "dose" should be prescribed, and how long treatment should continue. (hindawi.com)
  • Hemodynamic instability related to renal replacement therapy (HIRRT) is a frequent complication of all renal replacement therapy (RRT) modalities commonly used in the intensive care unit. (springer.com)
  • Patients' experiences of transitioning between different renal replacement therapy modalities: A qualitative study. (ugent.be)
  • This page last modified on Dec 13, 2019 @ 11:46 am . edren and edrep are produced by the Renal Unit at the Royal Infirmary of Edinburgh and the University of Edinburgh. (edren.org)
  • Continuous Renal Replacement Therapy market size was valued at USD 876.0 million in 2018 and is expected to witness 7.3% CAGR from 2019 to 2025. (gminsights.com)
  • When computer simulations were carried out and efficacy indexes were calculated, it was shown that polytraumatized patients and septic patients with conserved renal function may not achieve adequate efficacy indexes to deal with specific infections. (springer.com)
  • Incidence, underlying conditions, and outcomes of patients receiving acute renal replacement therapies in tertiary cardiac intensive care units: An analysis from the Critical Care Cardiology Trials Network Registry. (harvard.edu)
  • Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomized trial. (springer.com)
  • LJPC ) today announced the release of data from analyses of the impact of GIAPREZA™ (angiotensin II) on outcomes of a subset of patients with acute kidney injury requiring renal replacement therapy (AKI-RRT) enrolled in the ATHOS-3 (Angiotensin II for the Treatment of High Output Shock) study. (globenewswire.com)
  • The manuscript, entitled " Outcomes in patients with vasodilatory shock and renal replacement therapy treated with intravenous angiotensin II " was published online in Critical Care Medicine . (globenewswire.com)
  • The aim of this study was to compare the characteristics and outcomes of cancer and non-cancer patients requiring renal replacement therapy (RRT) for AKI in general ICUs. (oup.com)
  • We examined United States Renal Data System data (n = 1,677,303) for the years 1996 to 2012 to quantify the incidence and outcomes of ESKD from scleroderma treated with renal replacement therapy (n = 2398). (readbyqxmd.com)
  • Record whether renal replacement therapy (RRT) was medically indicated for acute renal disease. (cdisc.org)
  • The effect of 8 weeks of daily oral fish oil supplementation in a dose of 3 to 8 g/d on serum lipid levels was studied in 16 patients, 7 to 8 years of age, who had end-stage renal disease and were receiving renal replacement therapy. (aappublications.org)
  • Aboriginal and Torres Strait Islander people (respectfully referred to hereafter as Indigenous Australians) have a higher incidence of end-stage kidney disease requiring renal replacement therapy (RRT) than non-Indigenous Australians. (mja.com.au)
  • OBJECTIVE Risks of end-stage renal disease and premature death in patients with type 1 diabetes have declined over the past decades. (diabetesjournals.org)
  • Etiologies for AKI in this setting are often multifactorial and can include exposure to nephrotoxic medications, abdominal compartment physiology, hepatorenal syndrome, and de novo intrinsic renal disease [ 1 ]. (plos.org)
  • Underlying bleeding diatheses resulting from the primary disease process complicates anticoagulation in liver failure patients especially when extracorporeal therapies are used, with serious bleeding complications reported in 16-25% of patients [ 4 , 5 ]. (plos.org)
  • The purpose of this study is to investigate the efficacy of a decision support intervention on reducing conflict and improving satisfaction in making the renal replacement therapy decision among patients with end-stage renal disease. (clinicaltrials.gov)
  • We aimed to describe secular trends in the incidence of end-stage kidney disease (ESKD) requiring renal replacement therapy (RRT) in Japan, and to assess the effect of population aging on the incidence of ESKD. (nih.gov)
  • Liver disease of variable severity can be observed in about two thirds of hepatitis C virus-positive renal allograft recipients. (fmshk.com.hk)
  • Renal replacement is a procedure which involves the exchange of affected blood-filtering functioning of the kidneys which can be caused by kidney injuries and kidney disease. (medgadget.com)
  • According to National Center for Biotechnology Information (NCBI) in 2014, around 200 million people were diagnosed with chronic kidney disease, which may lead to the complete loss of renal failure or kidney injury and can also result in end-stage renal disease if left untreated. (medgadget.com)
  • North America is expected to dominate the global continuous renal replacement therapy market, and this can be attributed to the rising incidences of chronic kidney disease. (medgadget.com)
  • According to American Kidney Fund, in 2015, around 31 million people were diagnosed with chronic kidney disease and it is the ninth leading cause of death in the U.S. Moreover, an innovative technology called wearable artificial kidney launched in the U.S, in 2015 has been designed to provide continuous renal replacement 24 hours a day thus providing feasibility and affordability to the patients. (medgadget.com)
  • At the same time, Asia Pacific is projected to show a promising region for continuous renal replacement therapy market over the forecast timeline owing to the growing investment for improving healthcare infrastructure and the presence of large patients suffering from chronic disease. (medgadget.com)
  • It is often difficult to synthesize information about the risks and benefits of recommended management strategies in older patients with end-stage renal disease since they may have more comorbidity and lower life expectancy than patients described in clinical trials or practice guidelines. (pubmedcentralcanada.ca)
  • In this review, we outline a framework for individualizing end-stage renal disease management decisions in older patients. (pubmedcentralcanada.ca)
  • By combining quantitative estimates of benefits and harms with qualitative assessments of patient preferences, clinicians may be better able to tailor treatment recommendations to individual older patients, thereby improving the overall quality of end-stage renal disease care. (pubmedcentralcanada.ca)
  • Cell-free hemoglobin and lipid peroxidation are associated with acute kidney injury and disease severity in falciparum malaria, suggesting a pathophysiological role in renal tubular injury. (biomedcentral.com)
  • CKD Patient enrollment occurred if two criteria of high plasma creatinine level and chronicity of renal disease by at least 3 months of clinical history or small sized kidneys in ultrasound findings were met. (biomedcentral.com)
  • Active follow-up of CKD patients appears to significantly decrease the risk of death or progression to end-stage renal disease and the requirement to start renal replacement therapy. (biomedcentral.com)
  • Background: Progression of coronary artery calcification is an important marker for cardiovascular morbidity in end-stage renal disease patients. (uu.nl)
  • The disease was diagnosed using reliable renal imaging criteria. (oup.com)
  • Although the management of scleroderma continues to evolve, it is unknown whether the burden of end-stage kidney disease (ESKD) treated with maintenance renal replacement therapy from SD has changed. (readbyqxmd.com)
  • The Health-related Quality of Life (HRQOL) of children with end-stage renal disease influences their future life in terms of autonomy, psychosexual development, and social integration. (longdom.org)
  • Cross-sectional, observational, prospective study that included 79 children between 5 and 17 years of age (mean of 13.3 ± 3.4) diagnosed with End-Stage Renal Disease (with renal replacement therapy). (longdom.org)
  • It is generally accepted that renal hypoxia plays an important role in the progression of chronic kidney disease (CKD). (biomedcentral.com)
  • Is progression of coronary artery calcification influenced by modality of renal replacement therapy? (uu.nl)
  • How can we achieve global equity in provision of renal replacement therapy? (who.int)
  • Approximately 8000 people a year start renal replacement therapy in the UK. (bmj.com)
  • Worldwide, the number receiving renal replacement therapy (RRT) is estimated at more than 1.4 million, 1 with incidence growing by approximately 8% annually. (who.int)
  • These results show that dietary fish oil supplementation reduces serum TG levels in young patients receiving renal replacement therapy and improves their "atherogenic" serum lipoprotein profile. (aappublications.org)
  • Survival of Indigenous Australians receiving renal replacement therapy: closing the gap? (mja.com.au)
  • Data on the survival of patients receiving renal replacement therapy (RRT) are, however, limited. (diabetesjournals.org)
  • From 2004 to 2007 in Brazil, the number of patients receiving renal replacement therapy (RRT) increased by 8.1% ( 12 ). (asnjournals.org)
  • Cohorts of 45,000 patients starting maintenance renal replacement therapy (RRT) and 5.3 million hospital controls were identified from two large electronic hospital inpatient data sets: the Oxford Record Linkage Study (1965-1999) and all-England Hospital Episode Statistics (2000-2011). (ox.ac.uk)
  • Although results comparing patient survival in HD and PD are in conflict, the majority of studies found that both therapies have comparable results ( 7 , 8 ). (asnjournals.org)
  • The recurrence of glomerulonephritis (GN) is critical to the prognosis of long-term renal transplant graft survival. (biomedcentral.com)
  • As such, few studies have focused on patients having SLE treated with renal replacement therapy (RRT), and choosing the appropriate RRT is an important consideration to maximize survival and quality of life in these patients. (kjim.org)
  • Previous studies have reported similar cumulative survival rates between patients with SLE and non-SLE patients who received renal RRT [ 2 - 4 ]. (kjim.org)
  • Despite the poor prognosis associated with ARF, CVVHDF is an effective and tolerable renal replacement technique in patients with cancer admitted to the ICU. (frontiersin.org)
  • AN 69 dialyzers (M-60 and M-100, AN-69 membrane) were used in 83.33 percent (15/18) and PAES dialyzer (HF-20, PAES membrane) was used in 16.66 percent (3/18) of dogs during Continuous renal replacement therapy (CVVHDF). (thefreelibrary.com)
  • CVVHDF(Taken from Bagshaw S, Cruz N, Gibney RTN, Ronco C. A proposed algorithm for initiation of renal replacement therapy in adult critically ill patients. (cancertherapyadvisor.com)
  • Eighty patients with acute or chronic renal failure were included. (scielo.br)
  • The patients with acute renal failure also exhibited a reduction in peak pressure (p=0.024) and an increase in the dynamic compliance (p=0.026), whereas the patients with chronic renal failure exhibited an increase in the resistive pressure (p=0.046) and in the resistance of the respiratory system (p=0.044). (scielo.br)
  • Manske CL, Wang Y, Rector T, Wilson RF, White CF. Coronary revascularisation in insulin-dependent diabetic patients with chronic renal failure. (springer.com)
  • It is important to understand the distinction between RRT for chronic renal failure and RRT in the ICU setting (usually due to acute renal failure). (openanesthesia.org)
  • Therefore, in this paper, although we will discuss the situation of AKI due to crush injury as the paradigm for austere RRT, we will focus more on general practical aspects of managing patients who require RRT in austere settings, regardless of the cause of renal failure. (hindawi.com)
  • Heparin is the most commonly used anticoagulant for extracorporeal therapies but since it is systemically administered, it carries risks of hemorrhage as well as heparin induced thrombocytopenia leading to a search for other safer options. (plos.org)
  • Azotemia control by extracorporeal theraphy in patients with acute renal failure. (springer.com)
  • Extracorporeal therapies are now exclusively delivered through double-lumen venous catheters. (biomedcentral.com)
  • Any method attempting to provide extracorporeal blood purification in the presence of renal dysfunction with the aim of 24-hour-per-day support. (cancertherapyadvisor.com)
  • Based on the renal imaging criteria, AN was diagnosed in 30 of 328 registered patients, resulting in an AN incidence of 9.1% while the EDTA data only mentioned an incidence of 4.8% (period 1986-1989). (oup.com)
  • these methods include sanatorium and health resort treatment, physical therapy, and exercise therapy. (thefreedictionary.com)
  • Renal replacement therapy (RRT) is therapy that replaces the normal blood-filtering function of the kidneys. (wikipedia.org)
  • Renal replacement therapy (RRT) is required when the kidneys are functioning at less than 10-15 percent. (healthcommunities.com)
  • Early versus late initiation of renal replacement therapy in patients with acute kidney injury-a systematic review & meta-analysis of randomized controlled trials. (physiciansweekly.com)
  • Sanz Ganuza, M., Hidalgo Martínez, F. and García-Fernández, N. (2017) Circuit life span of continuous renal replacement therapy in critically ill patients with or without conventional anticoa-gulation: an observational prospective study. (ivteam.com)
  • Infections caused by pathogens with an MIC of ≥8 mg/L should not be treated with meropenem in polytraumatized patients without or with moderate renal failure because excessive doses of meropenem would be necessary. (springer.com)
  • Acute renal failure in critically ill patients: a multinational, multicanter study. (springer.com)
  • Clinical over-hydration is common in veterinary patients, especially in those presenting in oliguric or anuric renal failure. (mspca.org)
  • If this is unrecognized until the patient has symptoms of terminal renal failure, the nephrologist and the patient face a multitude of problems. (springer.com)
  • Bech-Hanssen O, Wallentin I, Larsson O, Nyberg G. Reduced left ventricular hypertrophy in Type 1 diabetic patients with end-stage renal failure. (springer.com)
  • Acute renal failure (ARF) has a poor prognosis in patients with cancer requiring intensive care unit (ICU) admission. (frontiersin.org)
  • Acute renal failure (ARF) is a frequent complication in patients with cancer. (frontiersin.org)
  • Patients were assigned to receive renal replacement therapy either within 12 hours after documentation of failure-stage AKI or after a delay of 48 hours if renal recovery did not occur. (healio.com)
  • Evaluation of Continuous Renal Replacement Therapy Effluent to Assess Filtration Efficiency of Dialyzers in Renal Failure dogs. (thefreelibrary.com)
  • Patients were included only if they had at least three consecutive months of treatment at the beginning of treatment to exclude acute renal failure patients. (asnjournals.org)
  • The overall focus will be on renal replacement and the clinical questions that arise during its application in renal failure. (omicsonline.org)
  • However, co-morbidities can obscure this criterion as the symptoms listed above may be due to co-morbidities and not renal failure. (brainscape.com)
  • Overview of pediatric renal replacement therapy in acute renal failure. (semanticscholar.org)
  • Predicting the outcome of renal replacement therapy in severe acute renal failure. (semanticscholar.org)
  • Diabetes is one of the major causes of renal failure that escalates the demand for renal therapies. (gminsights.com)
  • People suffering from Type 2 diabetes have significant probability of acquiring renal failure at later stages in life. (gminsights.com)
  • CVVHD is an effective treatment applicable in patients suffering from acute renal failure. (gminsights.com)
  • Improved cardiovascular stability during continuous modes of renal replacement therapy in critically ill patients with acute hepatic and renal failure. (semanticscholar.org)
  • PATIENTS Thirty-two consecutive, critically ill, mechanically ventilated patients with combined acute hepatic and renal failure. (semanticscholar.org)
  • In contrast, renal allograft recipients can develop potentially life-threatening exacerbations, as exemplified by fibrosing cholestatic hepatitis. (fmshk.com.hk)
  • Although renal-replacement therapy is the standard of care for severe acute kidney injury, the ideal time for initiation remains controversial. (nih.gov)
  • Renal replacement therapies (RRTs) represent a cornerstone in the management of severe acute kidney injury. (biomedcentral.com)
  • Some people decide not to receive renal replacement therapy but choose conservative management, which comprises full supportive management (including advance care planning and control of symptoms and complications). (bmj.com)
  • In the delayed-strategy group, 38% (93 patients) did not receive renal-replacement therapy. (nih.gov)
  • There were 38% of delayed strategy patients who did not receive renal replacement therapy. (healio.com)
  • anticoagulant therapy see anticoagulant therapy . (thefreedictionary.com)
  • Is the Subject Area "Anticoagulant therapy" applicable to this article? (plos.org)
  • Heparin is the most commonly prescribed anticoagulant for continuous renal replacement therapy. (biomedcentral.com)
  • We performed a systematic search of the literature to identify and quantify the effect of non-anticoagulant factors and interventions that influence filter life in continuous renal replacement therapy. (biomedcentral.com)
  • and if their removal is not addressed by either renal recovery or the initiation of artificial renal replacement therapy, the patient dies from uncontrolled hyperkalemia or uremia. (springer.com)
  • Continuous renal replacement therapies (CRRTs) allow for gradual solute and fluid removal. (nih.gov)
  • The occurrence of analgesic nephropathy (AN) among renal replacement therapy patients in former Czechoslovakia is not known. (oup.com)
  • Renal replacement therapy: is it effective in critically ill patients with acute kidney injury? (oalib.com)
  • CKD can lead to kidney injury and sometimes to kidney function loss, thus requiring renal replacement therapy. (webnewswire.com)
  • The natural cause of diabetic nephropathy is characterised by rapidly declining renal function. (springer.com)
  • Nordén G, Björck S, Granerus G, Nyberg G. Estimation of renal function in diabetic nephropathy. (springer.com)
  • Renal regenerative medicine therapies (RRMTs) aim to regenerate, repair or replace damaged renal tissue using cell, drug or gene therapies as well as tissue engineering in order to restore normal kidney function. (homedialysis.org)
  • Patients 80 years old or older are likely to recover sufficient renal function allowing renal replacement therapy discontinuation when baseline estimated glomerular filtration rate is above 44 mL/min/1.73 m2. (ovid.com)
  • The secondary outcome measures were: length of ICU stay, length of hospital stay, recovery of renal function and adverse events. (physiciansweekly.com)
  • Of note, 85% cancer patients recovered renal function at hospital discharge. (oup.com)
  • collapse therapy a formerly common treatment for pulmonary tuberculosis in which the diseased lung was collapsed in order to immobilize it and allow it to rest. (thefreedictionary.com)
  • Anticoagulation in continuous renal replacement therapy. (nih.gov)
  • Clinical review: Anticoagulation for continuous renal replacement therapy - heparin or citrate? (biomedcentral.com)
  • PrisMax simplifies the delivery of continuous renal replacement therapy and therapeutic plasma exchange to maximize care for critically ill patients. (mpo-mag.com)
  • It is important to ensure that people with acute kidney injury who need treatment receive it in the right care setting (such as an intensive care unit or renal unit) at the right time, and that delays in treatment that put people at risk are avoided. (nice.org.uk)
  • Renal replacement therapy in the pediatric cardiac intensive care unit. (harvard.edu)
  • Patient data of patients hospitalized on intensive care unit from 2009 to 2011 and had to undergo one sort of renal replacement therapy (RRT) - continuous or intermittent - was used. (srce.hr)
  • Unfortunately, AKI requiring renal replacement therapy (RRT) is relatively common in critically ill patients treated in the intensive care unit (ICU) and involves close to 5% of all admissions. (springer.com)
  • Bellomo R, Metha R. Acute renal replacement in the intensive care unit: now and tomorrow. (springer.com)
  • Up to 54% of patients with cancer admitted to the intensive care unit (ICU) develop ARF and some require renal replacement therapy (RRT) ( 3 - 5 ). (frontiersin.org)
  • Our team reviewed every piece of feedback from nephrologists, nurses and intensive care specialists, and then designed a system that can help simplify therapy administration and maximize efficiency," said Gavin Campbell, general manager of Baxter's U.S. renal business. (mpo-mag.com)
  • Acid-base disturbances in the intensive care unit: current issues and the use of continuous renal replacement therapy as a customized treatment tool. (biomedsearch.com)
  • Additionally, ethical aspects that are linked to renal replacement therapies in the intensive care setting are considered. (egms.de)
  • RRT is being used increasingly in the intensive care unit, not only for renal indications but also for other organ-supportive strategies. (biomedcentral.com)
  • Continuous renal replacement therapy was initiated in our intensive care unit. (biomedcentral.com)
  • The report at that point estimates 2018-2023 market development trends of Continuous Renal Replacement Therapy industry. (webnewswire.com)
  • Instruments segment of continuous renal replacement market was valued around USD 340 million in 2018 and is expected to witness significant growth in the near future. (gminsights.com)

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