The circulation of blood through the BLOOD VESSELS of the BRAIN.
The flow of BLOOD through or around an organ or region of the body.
Unstable isotopes of xenon that decay or disintegrate emitting radiation. Xe atoms with atomic weights 121-123, 125, 127, 133, 135, 137-145 are radioactive xenon isotopes.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.
A gamma-emitting RADIONUCLIDE IMAGING agent used in the evaluation of regional cerebral blood flow and in non-invasive dynamic biodistribution studies and MYOCARDIAL PERFUSION IMAGING. It has also been used to label leukocytes in the investigation of INFLAMMATORY BOWEL DISEASES.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.
A noble gas with the atomic symbol Xe, atomic number 54, and atomic weight 131.30. It is found in the earth's atmosphere and has been used as an anesthetic.
Unstable isotopes of oxygen that decay or disintegrate emitting radiation. O atoms with atomic weights 13, 14, 15, 19, and 20 are radioactive oxygen isotopes.
Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.
The arterial blood vessels supplying the CEREBRUM.
Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Analogs or derivatives of AMPHETAMINE. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopressin, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Determination of the shortest time interval between the injection of a substance in the vein and its arrival at some distant site in sufficient concentration to produce a recognizable end result. It represents approximately the inverse of the average velocity of blood flow between two points.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Pressure within the cranial cavity. It is influenced by brain mass, the circulatory system, CSF dynamics, and skull rigidity.
The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.
A noble gas that is found in the atmosphere. It has the atomic symbol Kr, atomic number 36, atomic weight 83.80, and has been used in electric bulbs.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Measurement of oxygen and carbon dioxide in the blood.
A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.
The making of a radiograph of an object or tissue by recording on a photographic plate the radiation emitted by radioactive material within the object. (Dorland, 27th ed)
The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.
Elements of limited time intervals, contributing to particular results or situations.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
The circulation of blood through the CORONARY VESSELS of the HEART.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.
Dominance of one cerebral hemisphere over the other in cerebral functions.
A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.
A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
The circulation of the BLOOD through the vessels of the KIDNEY.
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.
Scandium. An element of the rare earth family of metals. It has the atomic symbol Sc, atomic number 21, and atomic weight 45.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
The circulation of BLOOD through the LIVER.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Molecules which contain an atom or a group of atoms exhibiting an unpaired electron spin that can be detected by electron spin resonance spectroscopy and can be bonded to another molecule. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed)
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.
The circulation of the BLOOD through the LUNGS.
Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes.
Anesthesia caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Restoration of blood supply to tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. It is primarily a procedure for treating infarction or other ischemia, by enabling viable ischemic tissue to recover, thus limiting further necrosis. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing REPERFUSION INJURY.
Freedom from activity.
A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia, and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.
Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
Posterior portion of the CEREBRAL HEMISPHERES responsible for processing visual sensory information. It is located posterior to the parieto-occipital sulcus and extends to the preoccipital notch.
Radiography of the vascular system of the brain after injection of a contrast medium.
Drugs used to cause dilation of the blood vessels.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
The creation and display of functional images showing where the blood flow reaches by following the distribution of tracers injected into the blood stream.
Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
The processes whereby the internal environment of an organism tends to remain balanced and stable.
Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.
The innermost layer of the three meninges covering the brain and spinal cord. It is the fine vascular membrane that lies under the ARACHNOID and the DURA MATER.
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
Use of reflected ultrasound in the diagnosis of intracranial pathologic processes.
The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, atomic number 43, and atomic weight 98.91. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Large subcortical nuclear masses derived from the telencephalon and located in the basal regions of the cerebral hemispheres.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
Pathological conditions of intracranial ARTERIES supplying the CEREBRUM. These diseases often are due to abnormalities or pathological processes in the ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; and POSTERIOR CEREBRAL ARTERY.
The vessels carrying blood away from the heart.
The decrease in neuronal activity (related to a decrease in metabolic demand) extending from the site of cortical stimulation. It is believed to be responsible for the decrease in cerebral blood flow that accompanies the aura of MIGRAINE WITH AURA. (Campbell's Psychiatric Dictionary, 8th ed.)
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Paired bodies containing mostly GRAY MATTER and forming part of the lateral wall of the THIRD VENTRICLE of the brain.
A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule through inhibition of CARBONIC ANHYDRASES.
A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.
Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight.
A subfamily of the Muridae consisting of several genera including Gerbillus, Rhombomys, Tatera, Meriones, and Psammomys.
Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.
Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.
A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.
Clinical manifestation consisting of a deficiency of carbon dioxide in arterial blood.
A noninvasive technique that uses the differential absorption properties of hemoglobin and myoglobin to evaluate tissue oxygenation and indirectly can measure regional hemodynamics and blood flow. Near-infrared light (NIR) can propagate through tissues and at particular wavelengths is differentially absorbed by oxygenated vs. deoxygenated forms of hemoglobin and myoglobin. Illumination of intact tissue with NIR allows qualitative assessment of changes in the tissue concentration of these molecules. The analysis is also used to determine body composition.
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
Unstable isotopes of cerium that decay or disintegrate emitting radiation. Ce atoms with atomic weights 132-135, 137, 139, and 141-148 are radioactive cerium isotopes.
Elongated gray mass of the neostriatum located adjacent to the lateral ventricle of the brain.
Injections made into a vein for therapeutic or experimental purposes.
A form of compensated hydrocephalus characterized clinically by a slowly progressive gait disorder (see GAIT DISORDERS, NEUROLOGIC), progressive intellectual decline, and URINARY INCONTINENCE. Spinal fluid pressure tends to be in the high normal range. This condition may result from processes which interfere with the absorption of CSF including SUBARACHNOID HEMORRHAGE, chronic MENINGITIS, and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp631-3)
The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Intellectual or mental process whereby an organism obtains knowledge.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.
Veins draining the cerebrum.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
One of the convolutions on the medial surface of the CEREBRAL HEMISPHERES. It surrounds the rostral part of the brain and CORPUS CALLOSUM and forms part of the LIMBIC SYSTEM.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.
Unstable isotopes of nitrogen that decay or disintegrate emitting radiation. N atoms with atomic weights 12, 13, 16, 17, and 18 are radioactive nitrogen isotopes.
The act of constricting.
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
A drive stemming from a physiological need for WATER.
Substances used to allow enhanced visualization of tissues.
Sense of awareness of self and of the environment.
Cognitive disorders including delirium, dementia, and other cognitive disorders. These may be the result of substance use, trauma, or other causes.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.
A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
Impairment in the comprehension of speech and meaning of words, both spoken and written, and of the meanings conveyed by their grammatical relationships in sentences. It is caused by lesions that primarily affect Wernicke's area, which lies in the posterior perisylvian region of the temporal lobe of the dominant hemisphere. (From Brain & Bannister, Clinical Neurology, 7th ed, p141; Kandel et al., Principles of Neural Science, 3d ed, p846)
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)
A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
A language dysfunction characterized by the inability to name people and objects that are correctly perceived. The individual is able to describe the object in question, but cannot provide the name. This condition is associated with lesions of the dominant hemisphere involving the language areas, in particular the TEMPORAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, p484)
The ratio of alveolar ventilation to simultaneous alveolar capillary blood flow in any part of the lung. (Stedman, 25th ed)
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Derived from TELENCEPHALON, cerebrum is composed of a right and a left hemisphere. Each contains an outer cerebral cortex and a subcortical basal ganglia. The cerebrum includes all parts within the skull except the MEDULLA OBLONGATA, the PONS, and the CEREBELLUM. Cerebral functions include sensorimotor, emotional, and intellectual activities.
The posture of an individual lying face up.
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Area of the parietal lobe concerned with receiving sensations such as movement, pain, pressure, position, temperature, touch, and vibration. It lies posterior to the central sulcus.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.
Detection and counting of scintillations produced in a fluorescent material by ionizing radiation.
Unstable isotopes of fluorine that decay or disintegrate emitting radiation. F atoms with atomic weights 17, 18, and 20-22 are radioactive fluorine isotopes.
Area of the FRONTAL LOBE concerned with primary motor control located in the dorsal PRECENTRAL GYRUS immediately anterior to the central sulcus. It is comprised of three areas: the primary motor cortex located on the anterior paracentral lobule on the medial surface of the brain; the premotor cortex located anterior to the primary motor cortex; and the supplementary motor area located on the midline surface of the hemisphere anterior to the primary motor cortex.
Relatively complete absence of oxygen in one or more tissues.
Gases or volatile liquids that vary in the rate at which they induce anesthesia; potency; the degree of circulation, respiratory, or neuromuscular depression they produce; and analgesic effects. Inhalation anesthetics have advantages over intravenous agents in that the depth of anesthesia can be changed rapidly by altering the inhaled concentration. Because of their rapid elimination, any postoperative respiratory depression is of relatively short duration. (From AMA Drug Evaluations Annual, 1994, p173)
A group of methane-based halogenated hydrocarbons containing one or more fluorine and chlorine atoms.
Treatment process involving the injection of fluid into an organ or tissue.
A state in which there is an enhanced potential for sensitivity and an efficient responsiveness to external stimuli.
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. The prefrontal cortex receives afferent fibers from numerous structures of the DIENCEPHALON; MESENCEPHALON; and LIMBIC SYSTEM as well as cortical afferents of visual, auditory, and somatic origin.
The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Act of eliciting a response from a person or organism through physical contact.
The front part of the hindbrain (RHOMBENCEPHALON) that lies between the MEDULLA and the midbrain (MESENCEPHALON) ventral to the cerebellum. It is composed of two parts, the dorsal and the ventral. The pons serves as a relay station for neural pathways between the CEREBELLUM to the CEREBRUM.
The minute vessels that connect the arterioles and venules.
Delivery of drugs into an artery.
The inferior part of the lower extremity between the KNEE and the ANKLE.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
Ingvar, David H.; Lassen, Niels A. (1961). "Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 ... "Radioisotopic assessment of regional cerebral blood flow". Progress in Nuclear Medicine. 1: 376-409. PMID 4567822. Lassen, ... There is a Niels Lassen Award presented by the International Society for Cerebral Blood Flow and Metabolism (ISCBFM). ((The ... Olaf B. Paulson (1997). "Niels A. Lassen, M.D., Ph.D.: 1926-1997". Journal of Cerebral Blood Flow & Metabolism. 17 (10): 1005- ...
NREM sleep is characterized by decreased global and regional cerebral blood flow. It constitutes ~80% of all sleep in adult ... Mazoyer B, Houdé O, Joliot M, Mellet E, Tzourio-Mazoyer N (September 2009). "Regional cerebral blood flow increases during ... "Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): 1173-1197. doi:10.1093/ ... "Regional cerebral blood flow changes as a function of delta and spindle activity during slow wave sleep in humans". The Journal ...
Braun, A. (1 July 1997). "Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): ... This triggers the "continual-activation" mechanism to generate a data stream from the memory stores to flow through the ... A 2001 study showed evidence that illogical locations, characters, and dream flow may help the brain strengthen the linking and ... consolidation of semantic memories.[77] These conditions may occur because, during REM sleep, the flow of information between ...
Journal of Cerebral Blood Flow and Metabolism. 15 (4): 681-6. doi:10.1038/jcbfm.1995.85. PMID 7790418. Meiniel A (March 2001 ... Rahner-Welsch S, Vogel J, Kuschinsky W (July 1995). "Regional congruence and divergence of glucose transporters (GLUT1) and ... Hypendymal cells and ependymal cells both are secretory in nature; their processes project to local blood vessels and also to ... All capillaries in the central nervous system with a functional blood-brain barrier express glucose transporters (GLUT1). These ...
Journal of Cerebral Blood Flow and Metabolism. 9: 786-794. doi:10.1038/jcbfm.1989.112. PMID 2684992. Blin J, Ray CA, Chase TN, ... Piercey MF (1991). "Regional cerebral glucose metabolism compared in rodents and humans". Brain Research. 568: 215-222. doi: ... It is because of this higher basal rate of cerebral metabolism that lesions may appear in rodents but not in large, mature ... Kurumaji A, McCulloch J (1989). "Effects of MK-801 upon local cerebral glucose utilisation in conscious rats and in rats ...
Fallon BA, Keilp J, Prohovnik I, Heertum RV, Mann JJ (2003). "Regional cerebral blood flow and cognitive deficits in chronic ... and possibly testing for specific antibodies in the blood.[3][11] Blood tests are often negative in the early stages of the ... Regional Disease Vector Ecology Profile: Central Europe. DIANE Publishing. April 2001. p. 136. ISBN 9781428911437. . Archived ... Based on symptoms, tick exposure, blood tests[3]. Prevention. Prevention of tick bites (clothing the limbs, DEET), doxycycline[ ...
Braun, A. (1 July 1997). "Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): ...
Gk, Frank; Wh, Kaye; P, Greer; Cc, Meltzer; Jc, Price (November 20, 2000). "Regional Cerebral Blood Flow After Recovery From ... Since PET imaging enables analysis of cerebral physiology, Price led a study exploring whether cerebral blood flow (CBF) to the ... Price is also an associate editor of the Journal of Cerebral Blood Flow and Metabolism, a leading journal in the field. Price ... "Journal of Cerebral Blood Flow & Metabolism". SAGE Publications Ltd. November 3, 2015. Retrieved June 2, 2020. "People - Price ...
"Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): 1173-1197. doi:10.1093/ ... PET studies seem to indicate that there is a correlation between blood flow in the pontine tegmentum and REM sleep Pontine ... recent research suggests a role in providing sensory feedback to the cerebral cortex. Recent research has discovered that the ...
"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... Certain techniques such as fMRI image tissues (particularly cerebral tissues) by blood flow and thus show metabolism. Also, ... Lassen NA, Ingvar DH, Skinhøj E (October 1978). "Brain Function and Blood Flow". Scientific American. 239 (4): 62-71. Bibcode: ... Some studies require the labeling of a patient's own blood cells with a radionuclide (leukocyte scintigraphy and red blood cell ...
"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... Lassen, Niels A.; Ingvar, David H.; Skinhøj, Erik (October 1978). "Brain Function and Blood Flow". Scientific American. 239 (4 ... as well as the flow rates of streams and rivers. In geology, archaeology, and paleontology, natural radionuclides are used to ... 91092-3. Ingvar, David H.; Franzén, Göran (1974). "Distribution of cerebral activity in chronic schizophrenia". The Lancet. 304 ...
"Regional cerebral blood flow changes in female to male gender identity disorder". Psychiatry and Clinical Neurosciences. 64 (2 ... to compare the regional cerebral blood flow (rCBF) of 11 gynephilic FtM transsexuals with that of 9 androphilic cis females. ... the study did reveal that the gynephilic FtM transsexuals showed significant decrease in blood flow in the left anterior ... Savic I, Arver S (November 2011). "Sex dimorphism of the brain in male-to-female transsexuals". Cerebral Cortex. 21 (11): 2525- ...
"Reduced regional cerebral blood flow in non-psychotic violent offenders". Psychiatry Research: Neuroimaging. 98: 29-41. doi: ... Reduced Cerebral Blood Flow in Angular Gyrus. A couple of studies found reduced cerebral blood flow in angular gyrus of ... 2011). "Mindfulness practice leads to increases in regional brain gray matter density". Psychiatry Research: Neuroimaging. 191 ...
"The measurement of regional cerebral blood flow during glossolalia: A preliminary SPECT study". Psychiatry Research: ...
Marion, DW; Darby, J; Yonas, H (1991). "Acute regional cerebral blood flow changes caused by severe head injuries". J Neurosurg ...
August 2000). "Continuous monitoring of regional cerebral blood flow: experimental and clinical validation of a novel thermal ... Perfusion is measured as the rate at which blood is delivered to tissue, or volume of blood per unit time (blood flow) per unit ... extra blood flow in them is used for thermoregulation of a body. In addition to delivering oxygen, blood flow helps to ... Cerebral blood flow determination by rapid-sequence computed-tomography: theoretical analysis. Radiology 137: 679-686, December ...
Methionine enkephalin as a possible neuromodulator of regional cerebral blood flow. Experientia, 41(7), 932-933. https://doi. ...
Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include ... Collaborators (2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of ... The most concerning short-term adverse effects of stimulants, such as elevated blood pressure and heart rate, waned in long- ...
Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include ... following absorption into the blood stream, it is converted by red blood cell-associated enzymes to dextroamphetamine via ... Collaborators (2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of ...
"Effects of smoking on regional cerebral blood flow in neurologically normal subjects". Stroke: A Journal of Cerebral ... Smoking also has a deleterious effect on regional cerebral blood flow (rCBF). The chances of having a stroke increase with the ... Transfusion therapy lowers the risk for a new silent stroke in children who have both abnormal cerebral artery blood flow ... which measures cerebral blood flow velocity (CBFV) in the large intracranial arteries in the brain, has been shown in various ...
"Deep dyslexia and right hemisphere reading-a regional cerebral blood flow study". Aphasiology. 11 (12): 1139-1158. doi:10.1080/ ...
Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... following absorption into the blood stream, it is converted by red blood cell-associated enzymes to dextroamphetamine via ... After oral ingestion, lisdexamfetamine is broken down by enzymes in red blood cells to form L-lysine, a naturally occurring ... The most concerning short-term adverse effects of stimulants, such as elevated blood pressure and heart rate, waned in long- ...
Hosokawa C, Ochi H, Yamagami S, Yamada R (April 1997). "Regional cerebral blood flow and glucose utilization in spontaneously ... following a seizure it has been shown that sometimes cerebral blood flow is not proportionate to metabolism. While cerebral ... Hammers notes that cerebral bloodflow after a seizure can not account for the increase in PET activity observed. Regional ... Cerebral autoregulation typically ensures that the correct amount of blood reaches the various regions of the brain to match ...
Georgiadis J, Kortekaas R, Kuipers R, Nieuwenburg A, Pruim J, Reinders A, Holstege G (2006). "Regional cerebral blood flow ... Some women exhibit a sex flush, a reddening of the skin over much of the body due to increased blood flow to the skin. As a ... and vaginal blood flow". Archives of Sexual Behavior. 14 (5): 439-449. doi:10.1007/BF01542004. PMID 4062540. S2CID 6967042. ... They described a cycle that begins with excitement as blood rushes into the genitals, then reaches a plateau during which they ...
Newberg AB, Wintering NA, Morgan D, Waldman MR (November 2006). "The measurement of regional cerebral blood flow during ... The caudate head receives its blood supply from the lenticulostriate artery while the tail of the caudate receives its blood ... There is some indirect evidence that the caudate may perform this regulatory role by measuring the general activity of cerebral ... "Cerebral vascular territories - Radiology Reference Article - Radiopaedia.org". radiopaedia.org. McDougal, David. "Substantia ...
W. 8. Theodore.W. 1995 Regional cerebral blood flow during object naming and word reading. Hum. Brain Mapp. 3. 93"106. Heath, S ... Medial surface of cerebral hemisphere. Medial view. Deep dissection. Inner lingual gyrus, shown in the right cerebral ... significant activation when moving from high to low contrast words as well as a correlation between word length and regional ...
"Pattern of white matter regional cerebral blood flow and autoregulation in normal pressure hydrocephalus". Brain. 127 (Pt 5): ... of late ischemic complications after cerebral aneurysm surgery by the intraoperative measurement of cerebral blood flow". ... Pickard, JD; Mackenzie, ET (1973). "Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to ... The Role of Prostaglandins in the Control of the Cerebral Circulation') from the University of Cambridge in 1981. He is a ...
Regional Cerebral Blood Flow. Journal of Neurology, Neurosurgery & Psychiatry 1979;42:971. ...
1975) Regional Differences in β-Adrenergic Effects on Local Cerebral Blood Flow and Adrenergic Innervation. In: Langfitt T.W., ... Regional Differences in β-Adrenergic Effects on Local Cerebral Blood Flow and Adrenergic Innervation. ... "Continuous measurement of local cerebral blood flow, PaO2, PaCO2, and blood pressure in the nonanesthetized animal." Pflügers ... Tyramine-induced contraction of the isolated middle cerebral artery of the cat." In Brain and Blood Flow, R. W. Ross Russell, ...
J Cereb Blood Flow Metab. 2009 Jan;29(1):197-205. doi: 10.1038/jcbfm.2008.112. Epub 2008 Oct 1. Research Support, N.I.H., ... Global hemispheric and regional cerebral blood flow (CBF) at baseline and after return of spontaneous circulation (ROSC). Time ... Magnetic resonance imaging assessment of regional cerebral blood flow after asphyxial cardiac arrest in immature rats.. Manole ... Magnetic Resonance Imaging Assessment of Regional Cerebral Blood Flow after Asphyxial Cardiac Arrest in Immature Rats ...
... the complex changes of cerebral hemody-namics and oxygenation pattern with the development of cerebral vasospasm are ... Cerebral Blood Flow Cerebral Blood Volume Cerebral Vasospasm Regional Cerebral Blood Flow Near Infrared Spectroscopy These ... Non invasive measurement of regional cerebral blood flow and regional cerebral blood volume by near infrared spectroscopy and ... Noninvasive measurement of regional cerebral blood flow by near-infrared spectroscopy and indocyanine green. J Cereb Blood Flow ...
To investigate the effect of EA on regional cerebral blood flow, cognitive deficits, inflammation, and its probable mechanisms ... Electroacupuncture Improves Cognitive Deficits through Increasing Regional Cerebral Blood Flow and Alleviating Inflammation in ... using laser Doppler flowmetry to test changes of regional cerebral blood flow (rCBF); double antibody sandwich enzyme-linked ... in chronic cerebral ischemia (CCI) rats. Methods. Rats were assigned randomly into sham operation group (sham group) and ...
Gordon, C., Emans, S., Grace, E. et al. Regional Cerebral Blood Flow Differences During High-Caloric Food Challenge in Patients ... Regional Cerebral Blood Flow Differences During High-Caloric Food Challenge in Patients with Anorexia Nervosa Versus Normal ... was used to make positron emission tomographic measurements of regional cerebral blood flow (rCBF). We compared 8 young women ...
Distribution of regional cerebral blood flow in voluntarily diving rats. Message Subject (Your Name) has sent you a message ... The distribution of regional cerebral blood flow (rCBF) was examined in conscious, voluntarily diving rats using the brain ... A detailed examination of the regional distribution of cerebral blood flow revealed that almost all brain regions were ... Because some brain regions did not increase flow significantly during diving, these results suggest that not all brain regions ...
... and cerebral blood flow velocity (rCBFV), both the regions and the extent of these changes have not yet been defined. Therefore ... and cerebral blood flow velocity (rCBFV), both the regions and the extent of these changes have not yet been defined. Therefore ... we determined the pattern of regional cerebral perfusion mania patients and using patients with major depressive disorder (MDD ... we determined the pattern of regional cerebral perfusion mania patients and using patients with major depressive disorder (MDD ...
However, the effect on regional cerebral blood flow (CBF) is unknown. In this study, we measured regional CBF (rCBF) in ... However, the effect on regional cerebral blood flow (CBF) is unknown. In this study, we measured regional CBF (rCBF) in ... Regional cerebral blood flow during hyperventilation in patients with acute bacterial meningitis Clin Physiol. 2000 Sep;20(5): ... Regional cerebral blood flow abnormalities are frequent in patients with acute bacterial meningitis. Short-term ...
Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET. ST Grafton, JC Mazziotta ... Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET ... Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET ... Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET ...
Effects of sevoflurane, propofol, and adjunct nitrous oxide on regional cerebral blood flow, oxygen consumption, and blood ... the effects of sevoflurane and propofol as sole anesthetics and in combination with N2O on regional cerebral blood flow (rCBF ... These reductions in flow and metabolism were partly attenuated by adjunct N2O. S+N especially reduced the oxygen extraction ... Anesthetic agents, especially volatile anesthetics and nitrous oxide (N2O), are suspected to perturb cerebral homeostasis and ...
... Reza Nemati ... S. E. Mouridsen, C. Videboek, H. Sogaard, and A. R. Andersen, "Regional cerebral blood-flow measured by HMPAO and SPECT in a 5- ... L. A. OTuama, D. K. Urion, M. J. Janicek, S. T. Treves, B. Bjornson, and J. M. Moriarty, "Regional cerebral perfusion in ...
Dynamics and Control Mechanisms in Maintenance of Regional Cerebral Blood Flow. YURI E. MOSKALENKO, IVAN T. DEMCHENKO, ... Dynamics and Control Mechanisms in Maintenance of Regional Cerebral Blood Flow. YURI E. MOSKALENKO, IVAN T. DEMCHENKO, ... Dynamics and Control Mechanisms in Maintenance of Regional Cerebral Blood Flow. YURI E. MOSKALENKO, IVAN T. DEMCHENKO, ... are followed by an increase of local blood flow (LCBF) in regional brain cortex up to 0.3 to 0.4 ml per minute per 1 gm brain ...
Regional cerebral blood flow, as measured by dASL. [ Time Frame: 1 week, 6 and 12 months ]. Part I: regional cerebral blood ... Part II: regional cerebral blood flow, measured at 6 months and 12 months in AD participants and normal control participants. ... The aim of the study is to determine if regional cerebral blood flow, measured by dynamic arterial spin labeling (dASL), can be ... A Study to Assess Regional Cerebral Blood Flow as an Alzheimers Disease Biomarker Compared to Positron Emission Tomography in ...
We examined the possible relationship between the rate of cognitive deterioration and regional cerebral blood flow (rCBF) ... The progression of cognitive deterioration and regional cerebral blood flow patterns in Alzheimers disease: a longitudinal ...
Effect of Acetazolamide on Regional Cerebral Oxygen Saturation and Regional Cerebral Blood Flow. Makio Kaminogo, Akio Ichikura ... Effect of Acetazolamide on Regional Cerebral Oxygen Saturation and Regional Cerebral Blood Flow ... Effect of Acetazolamide on Regional Cerebral Oxygen Saturation and Regional Cerebral Blood Flow ... Effect of Acetazolamide on Regional Cerebral Oxygen Saturation and Regional Cerebral Blood Flow ...
Measurements of regional cerebral blood flow (rCBF), analysis ofcerebrospinal fluid, auditory brain stem responses (ABR) ... Cerebral dysfunction in fibromyalgia (FM): evidence from regional cerebral blood flow measurements, otoneurological tests & ... Measurements of regional cerebral blood flow (rCBF), analysis of. cerebrospinal fluid, auditory brain stem responses (ABR) and ... normal flow level with slight but significant focal flow. decreases in dorsolateral frontal cortical areas of both. hemispheres ...
Duncan, Roderick (1993) Regional Cerebral Blood Flow in Focal Epilepsy. PhD thesis, University of Glasgow. ... have been used to study regional cerebral blood flow (rCBF) in patients with focal epilepsy. The main finding has been of focal ... there was no practical way to study regional cerebral blood flow during or soon after seizures. When the present work was ... Until the development of the blood flow tracer HMPAO (hexamethylpropyleneamine oxime) ...
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and ... Circadian and homeostatic modulation of functional connectivity and regional cerebral blood flow in humans under normal ... and regional cerebral blood flow (rCBF) in healthy human volunteers, using whole-brain resting-state functional magnetic ...
Noninvasive measurements of regional cerebral blood flow using technetium-99m hexamethylpropylene amine oxime MATSUDA H. ... Quantitative Measurements of Regional Cerebral Blood Flow Using Technetium-99m-L,L-ECD SPECT Activated with Acetazolamide: ... The effect of acetazolamide on regional cerebral blood flow in patients with Alzheimers disease or stroke as measured by ... Noninvasive Quantitative Measurements of Regional Cerebral Blood Flow Using Technetium-99m-L,L-ECD SPECT Activated with ...
Selective effects of cocaine on regional cerebral blood flow in the rat.. E A Stein and S A Fuller ... Selective effects of cocaine on regional cerebral blood flow in the rat.. E A Stein and S A Fuller ... Selective effects of cocaine on regional cerebral blood flow in the rat.. E A Stein and S A Fuller ... Selective effects of cocaine on regional cerebral blood flow in the rat. ...
Relationship between regional cerebral blood flow and separate symptom clusters of major depression : a single photon emission ... Regional cerebral blood flow in depression measured by positron emission tomography : the relationship with clinical dimensions ... Statistical parametric mapping analysis of the relationship between regional cerebral blood flow and symptom clusters of the ... Correlation between cerebral blood flow and items of the Hamilton rating scale for depression in anti-depressant-naive patients ...
Perfusion CT performed for the evaluation of regional cerebral blood flow (rCBF) involves sequential acquisition of cerebral CT ... Summary: Perfusion CT studies of regional cerebral blood flow (rCBF), involving sequential acquisition of cerebral CT sections ... Using 80 kVp versus 120 kVp in Perfusion CT Measurement of Regional Cerebral Blood Flow. Max Wintermark, Philippe Maeder, ... Simultaneous Measurement of Regional Cerebral Blood Flow by Perfusion CT and Stable Xenon CT: A Validation Study ...
Long-term effects of tacrine on regional cerebral blood flow changes in Alzheimers disease. Minthon, Lennart LU ; Nilsson, ... Regional cerebral blood flow (rCBF) was studied in patients with Alzheimers disease (AD) before and after 14 months of tacrine ... Regional cerebral blood flow (rCBF) was studied in patients with Alzheimers disease (AD) before and after 14 months of tacrine ... article{a42a0f99-94fd-4913-b3c1-936a0a2ea31b, abstract = {Regional cerebral blood flow (rCBF) was studied in patients with ...
Regional cerebral blood flow, white matter abnormalities, and cerebrospinal fluid hydrodynamics in patients with idiopathic ... Regional cerebral blood flow, white matter abnormalities, and cerebrospinal fluid hydrodynamics in patients with idiopathic ...
The goal of this study was to determine if regional cerebral blood flow (rCBF)in the left and right hemithalami or the left and ... To determine if regional cerebral blood flow (rCBF). in the left and right hemithalami or the left and right heads. of the ... Abnormalities of regional cerebral blood flow in the thalamus & the caudate nucleus are associated with low pain threshold ... Anti-Aging Blood Sugar Control Cholesterol Colds & Flu Detoxification Digestion Liver Health Lyme Support Mens Health Muscle ...
... in the early period after cerebral ischemia/reperfusion (CI/R). Methods: The adenovirus carried human tiss ... The aims of this study were to find out whether kallikrein could induce angiogenesis and affect the cerebral blood flow (rCBF) ... Kallikrein gene transfer induces angiogenesis and further improves regional cerebral blood flow in the early period after ... The aims of this study were to find out whether kallikrein could induce angiogenesis and affect the cerebral blood flow (rCBF) ...
Autoregulation of cerebral blood flow: influence of the arterial blood pressure on the blood flow through the cerebral cortex. ... Hyperacute stroke: simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue ... Simultaneous Measurement of Regional Cerebral Blood Flow by Perfusion CT and Stable Xenon CT: A Validation Study. Max ... Using 80 kVp versus 120 kVp in perfusion CT measurement of regional cerebral blood flow. AJNR Am J Neuroradiol 2000;21:1881- ...
Regional Cerebral Blood Flow and Glucose Utilization during Hypothermia in Newborn Dogs. Anesthesiology 11 1989, Vol.71, 730- ... Regional Cerebral Blood Flow and Glucose Utilization during Hypothermia in Newborn Dogs ... Charles Palmer, Robert C. Vannucci, Melanie A. Christensen, Robert M. Brucklacher; Regional Cerebral Blood Flow and Glucose ... Regional Cerebral Blood Flow and Glucose Utilization during Hypothermia in Newborn Dogs ...
Longitudinal changes in cognitive function and regional cerebral function in Alzheimers disease: a SPECT blood flow study.J ... Quantitative changes in mesial temporal volume, regional cerebral blood flow cognition in Alzheimers disease.Arch Gen ... larger studies to investigate the effects of acetylcholinesterase inhibitors on regional cerebral blood flow. ... Donepezil hydrochloride preserves regional cerebral blood in patients with Alzheimers disease.J Nucl Med. 2001; 42: 1441-1445. ...
  • The tracer, oxygen 15-labeled carbon dioxide, was used to make positron emission tomographic measurements of regional cerebral blood flow (rCBF). (nature.com)
  • The distribution of regional cerebral blood flow (rCBF) was examined in conscious, voluntarily diving rats using the brain blood flow tracer N-[14C]isopropyl-p-iodoamphetamine and quantitative autoradiography. (biologists.org)
  • While evidence that episodes of mania in bipolar I are associated with changes in bioenergetic and regional cerebral blood flow (rCBF) and cerebral blood flow velocity (rCBFV), both the regions and the extent of these changes have not yet been defined. (frontiersin.org)
  • On all participants, Transcranial Doppler (TCD) was conducted to measure rCBFV parameters, 320-slice CT was conducted to measure rCBF in the different cerebral artery regions, and hematological parameters were assessed. (frontiersin.org)
  • In this study, we measured regional CBF (rCBF) in patients with acute bacterial meningitis before and during short-term hyperventilation. (nih.gov)
  • Using standard templates to identify regions of interest (ROIs), we calculated rCBF in percentage of cerebellar (99mTc-HMPAO images) or mean hemispheric (133Xe images) flow for each ROI, the degree of side-to-side asymmetry for each ROI, and the anterior-to-posterior flow ratio. (nih.gov)
  • On 99mTc-HMPAO images (n=12), relative rCBF and the anterior-to-posterior flow ratio were significantly lower in patients than in controls in the frontal and parietal cortex as well as in the basal ganglia. (nih.gov)
  • The authors quantified the effects of sevoflurane and propofol as sole anesthetics and in combination with N2O on regional cerebral blood flow (rCBF), metabolic rate of oxygen (rCMRO2), and blood volume (rCBV) in the living human brain using positron emission tomography. (nih.gov)
  • We examined the possible relationship between the rate of cognitive deterioration and regional cerebral blood flow (rCBF) patterns in patients with AD. (nih.gov)
  • Background and Purpose To verify whether the monitoring of regional cerebral oxygen saturation (rSO 2 ) with transcranial near-infrared spectroscopy would successfully reflect changes in intracranial hemodynamics but not changes in extracranial compartment, we measured rSO 2 and regional cerebral blood flow (rCBF) simultaneously in seven patients with cerebral ischemia and five normal volunteers before and after acetazolamide administration. (ahajournals.org)
  • Measurements of regional cerebral blood flow (rCBF), analysis of cerebrospinal fluid, auditory brain stem responses (ABR) and oculomotor tests were performed in 19 patients with fibromyalgia. (prohealth.com)
  • The results from the rCBF measurements showed a normal flow level with slight but significant focal flow decreases in dorsolateral frontal cortical areas of both hemispheres. (prohealth.com)
  • In recent years in vivo imaging techniques, principally single photon emission computed tomography (SPECT), have been used to study regional cerebral blood flow (rCBF) in patients with focal epilepsy. (gla.ac.uk)
  • To address this issue, we explicitly examined the effects of circadian and homeostatic regulation on functional connectivity (FC) and regional cerebral blood flow (rCBF) in healthy human volunteers, using whole-brain resting-state functional magnetic resonance imaging (rs-fMRI) and arterial spin labeling (ASL). (sigmaaldrich.com)
  • However, because of the pharmacokinetic properties of cocaine, brief duration of action and complex behavioral actions, regional cerebral blood flow (rCBF), a rapid marker of neuronal activity, was used to identify structures involved in different temporal aspects of its pharmacologic profile. (aspetjournals.org)
  • Summary: Perfusion CT studies of regional cerebral blood flow (rCBF), involving sequential acquisition of cerebral CT sections during IV contrast material administration, have classically been reported to be achieved at 120 kVp. (ajnr.org)
  • Perfusion CT performed for the evaluation of regional cerebral blood flow (rCBF) involves sequential acquisition of cerebral CT sections obtained in axial mode during IV administration of iodinated contrast material. (ajnr.org)
  • Regional cerebral blood flow (rCBF) was studied in patients with Alzheimer's disease (AD) before and after 14 months of tacrine treatment. (lu.se)
  • At baseline the two groups showed an identical rCBF and mean hemispheric blood flow. (lu.se)
  • article{a42a0f99-94fd-4913-b3c1-936a0a2ea31b, abstract = {Regional cerebral blood flow (rCBF) was studied in patients with Alzheimer's disease (AD) before and after 14 months of tacrine treatment. (lu.se)
  • The aim of this study was to investigate the differences in regional cerebral blood flow (rCBF) between two groups of subjects exposed to different types of traumatic stressor either developing or not PTSD. (cnr.it)
  • For CBF 1 the regional CO 2 response was a 3.1-3.9% increase in rCBF/mm Hg increase in CO 2 - Regional cerebral blood flow (ml/g/min) ranged from 0.64 ± 0.05-0.83 ± 0.15 at Paco 2 of 19 mm Hg to 1.34 ± 0.11-1.80 ± 0.33 at Paco 2 of 41 mm Hg to 2.61 ± 0.26-3.72 ± 0.37 at Paco 2 of 59 mm Hg (mean ± SEM). (ovid.com)
  • These results show that rCBF is well maintained in normal cerebral tissue when mean BP is decreased to below the autoregulatory threshold during controlled hypotension with deep isoflurane anesthesia. (ovid.com)
  • To gain insights into the working mechanism of morphine, regional cerebral blood flow (rCBF) patterns after morphine administration were assessed in dogs. (avmi.net)
  • Critical regional cerebral blood flow (rCBF) has been defined as the rCBF below which electroencephalographic (EEG) changes of ischemia occur. (ovid.com)
  • This study determined the rCBF50, the rCBF value at which 50% of patients will not demonstrate EEG evidence of cerebral ischemia with carotid cross-clamping. (ovid.com)
  • Although the core of the diagnostic process in dementia rests firmly on clinical and cognitive assessments, a wide range of investigations are available to aid diagnosis.Regional cerebral blood flow (rCBF) single-photon emission computed tomography (SPECT) is an established clinical tool that uses an intravenously injected radiolabelled tracer to map blood flow in the brain. (altmetric.com)
  • This pattern of blood flow is different to patterns seen in other subtypes of dementia and so can be used to differentiate FTD.It has been proposed that a diagnosis of FTD, (particularly early stage), should be made not only on the basis of clinical criteria but using a combination of other diagnostic findings, including rCBF SPECT. (altmetric.com)
  • The influence of such therapy on regional cerebral blood flow (rCBF) remains, however, unknown. (ku.dk)
  • This thesis utilized radioisotope-labeled tracers to investigate the distribution of cardiac output and regional cerebral blood flow (rCBF) during a mammalian diving response. (usask.ca)
  • The present study addressed the question of hemispheric asymmetry of frontal regions and aimed to further understand the acute effects of high- and low-frequency rTMS on regional cerebral blood flow (rCBF). (mpg.de)
  • Previous studies found changes in regional cerebral blood flow (rCBF) patterns related to both age and various cognitive tasks. (nova.edu)
  • To test the hypothesis that regional cerebral blood flow (rCBF) is normally regulated by regional metabolic activity, rCBF and the regional cerebral metabolic rate for oxygen (rCMRO 2 ) were compared in selected human subjects. (jamanetwork.com)
  • The authors examined the possible correlation between the rCBF values obtained by PET and the blood flow speed readings measured by TCD in MCAs. (elsevier.com)
  • We measured the regional cerebral blood flow (rCBF) using the Xenon inhalation method in 31 treatment-refractory patients with OCD and the same number of age-matched normal controls. (elsevier.com)
  • Patients with Alzheimer disease (AD) had reduced regional cerebral blood flow (rCBF) in the posterior parietotemporal region compared with controls, as determined with technetium-99m hexamethyl propyleneamine oxime and single photon emission tomography. (ox.ac.uk)
  • The regional cerebral blood flow (rCBF) measure has been proposed as a biomarker for HIV-associated CNS damage. (ismrm.org)
  • To identify associated changes in the functional brain response, we studied performance measures and regional cerebral blood flow (rCBF) using positron emission tomography (PET) in healthy subjects during performance of a WM task. (imtlucca.it)
  • To examine the contributions of the amygdala and other limbic and paralimbic regions to emotional processing, we exposed healthy subjects to aversive olfactory stimuli while measuring regional cerebral blood flow (rCBF) with positron emission tomography. (pnas.org)
  • We used H(2)15O positron emission tomography (PET) to measure age-related changes in regional cerebral blood flow (rCBF) during a verbal recognition memory task. (uky.edu)
  • The authors analyzed how the regional cerebral blood flow (rCBF) findings of patients with major depression differ from the normal control , and our results were compared to previous reports . (bvsalud.org)
  • Regional cerebral blood flow (rCBF) of 16 drug-free Brazilian patients with OCD and 17 healthy subjects matched for age, gender, handedness and level of education was measured with [99m-Tc] HMPAO single photon emission computed tomography. (unicamp.br)
  • We investigated the regional cerebral blood flow (rCBF) in SW using perfusion MRI (pMRI) and evaluated the relationships between altered rCBF and sleep, mood, psychometric measures, and quality of life. (bvsalud.org)
  • Interestingly, we also observed that motor skill training induced significant increases in regional cerebral blood flow (rCBF) in both task and resting states as the practice progressed. (ox.ac.uk)
  • Our study intent was to assess adolescent regional cerebral blood flow (rCBF) as it relates to current and future alcohol use. (uthscsa.edu)
  • Serial determinations of regional cerebral blood flow (rCBF) in the cortex and deep-seated areas (internal capsule, thalamus, and caudate nucleus) were made during the following 2 hours, while intracranial pressure (ICP) was maintained at normal values. (thejns.org)
  • To investigate the effect of EA on regional cerebral blood flow, cognitive deficits, inflammation, and its probable mechanisms in chronic cerebral ischemia (CCI) rats. (hindawi.com)
  • Kallikrein gene transfer induces angiogenesis and further improves regional cerebral blood flow in the early period after cerebral ischemia/reperfusion in rats. (biomedsearch.com)
  • 10 to 15 cc/[100 g × min], whereas penumbra, relating to reversible cerebral ischemia, happens with CBF between 15 and 20 cc/[100 g × min] (6-8) . (ajnr.org)
  • The EEG signal demonstrated the necessary amplitude, frequency, and stability for the accurate detection of cerebral ischemia in all patients within the range of 0.6-1.2% sevoflurane in 50% N2 O. (ovid.com)
  • In vivo , BID-knockout (KO) mice and wild type (WT) mice were subjected to 60 min of transient middle cerebral artery occlusion (tMCAO) to induce focal cerebral ischemia, and allowed to recover for 24 h. (frontiersin.org)
  • In conclusion, our data suggest that BID deficiency is neuroprotective in an in vitro model and modulates the inflammatory response to focal cerebral ischemia in vivo . (frontiersin.org)
  • Frackowiak RS, Lenzi GL, Jones T, Heather JD (1980) Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 150 and positron emission tomography: theory, procedure, and normal values. (springer.com)
  • This paper investigates the relationship between the blood oxygenation level dependent (BOLD) contrast effect and regional cerebral blood flow using the techniques of functional MRI (fMRI) and positron emission tomography (PET). (semanticscholar.org)
  • No effects of short-term GSM mobile phone radiation on cerebral blood flow measured using positron emission tomography. (emf-portal.org)
  • We characterized regional and temporal changes in CBF from 5 to 150 mins after asphyxial CA of increasing duration (8.5, 9, 12 min) in postnatal day (PND) 17 rats using the noninvasive method of arterial spin-labeled magnetic resonance imaging (ASL-MRI). (nih.gov)
  • We also assessed blood-brain barrier (BBB) permeability, and evaluated the relationship between CBF and mean arterial pressure after resuscitation. (nih.gov)
  • Relationship between mean arterial pressure (MAP) and cerebral blood flow (CBF). (nih.gov)
  • In cases of distal arterial narrowing, techniques measuring regional values of local cortical perfusion, representing se-lected vascular territories, may be more sensitive. (springer.com)
  • The aim of the study is to determine if regional cerebral blood flow, measured by dynamic arterial spin labeling (dASL), can be a biomarker for stage of Alzheimer's disease. (clinicaltrials.gov)
  • Since the intracranial microvasculature consists of approximately 75% venous, 20% arterial, and 5% capillary blood, 6 7 the oximeter reading is weighted toward venous blood oxygen saturation, representing oxygen extraction by the cerebral tissue. (ahajournals.org)
  • This study was performed to determine whether stimulation of the carotid chemoreceptors increases total or regional cerebral blood flow and whether activation of arterial chemoreceptors contributes to cerebral vasodilation during systemic hypoxemia. (ahajournals.org)
  • The primary outcome measure is changes in regional cerebral blood flow from baseline in the arterial territories of the anterior cerebral artery, medial cerebral artery and the posterior cerebral artery, measured by CT perfusion scan. (biomedcentral.com)
  • Increase in regional cerebral blood flow following experimental arterial air embolism. (elsevier.com)
  • Arterial pressure and blood flow were used to calculate vascular resistance. (uky.edu)
  • Arterial spin labeling (ASL) MRI is a novel noninvasive technique that can measure regional CBF. (psychiatryinvestigation.org)
  • Experimental brain injury resulted in changes in arterial blood pressure, CBF, and pial arteriolar diameter that were related to the severity of the injury. (utmb.edu)
  • Dopaminergic modulation of regional cerebral blood flow: An arterial spin labelling study of genetic and pharmacological manipulation of COMT activity. (ox.ac.uk)
  • We then assessed regional cerebral blood flow at rest using pulsed arterial spin labelling. (ox.ac.uk)
  • Ten patients with a presenile (before 65 years old) onset of the disease and 16 with senile onset of the disease were evaluated clinically and neuropsychologically and studied with single photon emission computed tomography using the blood flow tracer [ 123 I] N -isopropyl-p-iodoamphetamine. (jamanetwork.com)
  • No significant alterations were found in regional cortical perfusion, indicating that the increased binding index was not a consequence of increased tracer delivery. (ugent.be)
  • Selectively reduced regional cortical volumes in post-traumatic stress disorder. (semanticscholar.org)
  • Recently, short-term visual deprivation has been shown to affect a variety of non-visual processes and regional cortical activity (Sathian & Zangaladze, 2001). (arvojournals.org)
  • To keep up with the nutritional and waste removal demands of a higher metabolic rate, cerebral blood flow to the cortical area in use must increase proportionally. (wikipedia.org)
  • Photoelectric cells in a spectrophotometer device worn on the forehead measure the amount of each wavelength of light reflected by cerebral blood flow in the activated cortical tissue and send the data to a computer, which then calculates the ratio of red to infrared light and translates it into a visual signal of corresponding to oxygenation level on a graphical interface the patient can see. (wikipedia.org)
  • 1975) Regional Differences in β -Adrenergic Effects on Local Cerebral Blood Flow and Adrenergic Innervation. (springer.com)
  • Discrepancies between radiographic findings and delayed ischemic deficits may depend on the relationship between local cerebral oxygen-requirement and -deliv-ery, which only can be determined if cerebral blood flow (CBF) and cerebral oxy-gen extraction can be estimated. (springer.com)
  • There is evidence showing increased resting energy expenditure in manic episode patients, suggesting an altered regulation of energy and local cerebral blood flow in mania ( 3 ). (frontiersin.org)
  • After subarachnoid hemorrhage (SAH), the complex changes of cerebral hemody-namics and oxygenation pattern with the development of cerebral vasospasm are underestimated if transcranial Doppler (TCD) monitoring and angiography are considered singularly. (springer.com)
  • Furthermore, techniques based on jugular bulb cat-heters, represent only global cerebral oxygenation and perfusion. (springer.com)
  • As a simple but reliable method to evaluate in-tracerebral oxygenation, transcranial NIRS has become widely used to monitor cerebral hemodynamics and oxygenation. (ahajournals.org)
  • Along with the increase in flow, hemoglobin molecules in the blood, which are responsible for the transport and transference of oxygen to tissue throughout the body, must increase the amount of oxygen they deliver to the activated region of the cortex, resulting in a greater local blood oxygenation level. (wikipedia.org)
  • Developed by Dr. Hershel Toomim, near infrared hemoencephalography measures changes in the local oxygenation level of the blood. (wikipedia.org)
  • Similar to functional magnetic resonance imaging, which uses changes in the magnetic properties of blood resulting from oxygenation to form an image of brain activity, NIR utilizes the changes in blood translucence resulting from oxygenation to generate a signal that can be consciously manipulated in neurofeedback sessions. (wikipedia.org)
  • In contrast, the amount of infrared light scattered by the blood is largely impermeable to changes in the oxygenation level of hemoglobin. (wikipedia.org)
  • PIR uses a sensor similar to the NIR sensor to detect light from a narrow band of the infrared spectrum that corresponds to the amount of heat being generated by an active brain region, as well as the local blood oxygenation level. (wikipedia.org)
  • In: Langfitt T.W., McHenry L.C., Reivich M., Wollman H. (eds) Cerebral Circulation and Metabolism. (springer.com)
  • These reductions in flow and metabolism were partly attenuated by adjunct N2O. (nih.gov)
  • A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation. (semanticscholar.org)
  • This study aims to evaluate changes in regional metabolism and cerebral perfusion in subjects who used methamphetamine (METH) prior to sustaining a TBI. (elsevier.com)
  • We hypothesized that METH use would decrease pericontusional cerebral perfusion and markers of neuronal metabolism, in TBI patients compared to those without METH use. (elsevier.com)
  • There is a Niels Lassen Award presented by the International Society for Cerebral Blood Flow and Metabolism (ISCBFM). (wikipedia.org)
  • and was the first recipient of the inaugural International Society for Cerebral Blood Flow and Metabolism (ISCBFM) Lifetime Achievement Award in 1997. (wikipedia.org)
  • Methods A middle cerebral artery occlusion (MCAO) model was first established. (bmj.com)
  • abstract = "REGIONAL HEMODYNAMIC DISTURBANCES may complicate the treatment of certain cerebral arteriovenous malformations (AVM) and occasionally produce life-threatening situations. (elsevier.com)
  • J Cereb Blood Flow Metab. (nih.gov)
  • Results of computer tomography and measurement of regional cerebral blood flow]. (arctichealth.org)
  • With his colleague Ole Munck he began in the 1950s to use radioactive isotopes for the measurement of the blood circulation in the brain, and in the beginning of the 1960s he together with David H. Ingvar [sv] from University of Lund began the development of methods for regional measurements on the brain with krypton-85 and xenon-133 isotopes. (wikipedia.org)
  • Magnetic resonance imaging assessment of regional cerebral blood flow after asphyxial cardiac arrest in immature rats. (nih.gov)
  • Distribution of regional cerebral blood flow in voluntarily diving rats. (biologists.org)
  • The pattern of blood flow within the brain was also investigated during voluntarily initiated diving in rats. (usask.ca)
  • It is concluded that an oxygen conserving response, involving a redistribution of blood flow toward the brain, occurs during voluntarily initiated diving in rats. (usask.ca)
  • Ocular and regional cerebral blood flow in aging Fischer-344 rats. (uky.edu)
  • Vascular resistance was not different in other cerebral tissues or in the spinal cord in the aged rats. (uky.edu)
  • These data suggest that regional cerebral and spinal blood flow and vascular resistance remain largely unchanged in conscious aged rats at rest but that elevations in ocular vascular resistance and, correspondingly, decreases in ocular perfusion with advanced age could have serious adverse effects on visual function. (uky.edu)
  • Objective To examine for an opening effect on the blood-brain barrier (BBB) in intact rats and rats with experimental ischaemia-reperfusion (I/R) during the recovery period after various electroacupuncture (EA) treatments with different time courses, and to determine whether there is a time-dependent effect. (bmj.com)
  • Nevertheless first examinations in patients with SAH show that the sensitivity of the new method to detect cerebral vasospasm may be limited by the technique measuring only global CBF values [11]. (springer.com)
  • A decrease in the jugular bulb oxygen saturation (SjvO 2 ) may be useful only in detecting severe prox-imal cerebral vasospasm, leading to significant reduction of hemispheric blood flow. (springer.com)
  • The sensitivity of SjvO 2 to detect smaller ischemic areas secondary to cerebral vasospasm of single vessels is limited [11]. (springer.com)
  • Moreover, cerebral vasospasm may occur in different vascular territories not observed with the PbtO 2 -monitoring. (springer.com)
  • Vora YY, Suarez-Almazor M, Steinke DE, Martin ML, Findlay JM (1999) Role of transcranial Doppler monitoring in the diagnosis of cerebral vasospasm after subarachnoid hemorrhage. (springer.com)
  • One of the main causes of mortality and morbidity following subarachnoid haemorrhage (SAH) is the development of cerebral vasospasm, a frequent complication arising in the weeks after the initial bleeding. (biomedcentral.com)
  • In vitro models have shown a relaxing effect of prostacyclin after induced contraction in cerebral arteries, and a recent pilot trial showed a positive effect on cerebral vasospasm in a clinical setting. (biomedcentral.com)
  • The secondary outcomes will be vasospasm measured by CT angiography, ischaemic parameters measured by brain microdialysis, flow velocities in the medial cerebral artery, clinical parameters and outcome (Glasgow Outcome Scale) at 3 months. (biomedcentral.com)
  • however, measurements obtained soon after the onset of focal symptoms suggest that the only CBF decreases directly produced by vasospasm in Grade III patients are regional changes. (elsevier.com)
  • Higher BMI is linked to decreased cerebral blood flow, which is associated with increased risk of Alzheimer's disease and mental illness. (reddit.com)
  • Hyperventilation is frequently used to prevent or postpone the development of cerebral edema and intracranial hypertension in patients with fulminant hepatic failure (FHF). (ku.dk)
  • Single Photon Emission Computerised Tomography (SPECT) was carried out to measure regional cerebral blood flow in DAT patients and controls. (gla.ac.uk)
  • The Tc-99m ECD brain perfusion SPECT findings in our study did not differ from the previously reported regional cerebral blood flow pattern of patients with major depression . (bvsalud.org)
  • CBFv (transcranial Doppler ultrasound) was measured concurrently in the posterior cerebral artery (PCA) and the middle cerebral artery (MCA). (arvojournals.org)
  • There was significant positive correlation between the total score of SRS-A and the regional cerebral blood flow (CBF) in posterior cingulate cortex (PCC). (psychiatryinvestigation.org)
  • It is a small glandular structure that is located in the posterior region of the third ventricle, near the entrance of the cerebral aqueduct. (wikipedia.org)
  • Systemic hypoxemia produced large and equivalent increases in cerebral blood flow before and after chemodenervation. (ahajournals.org)
  • PIR has a poorer resolution than NIR and this treatment typically focuses on more global increases in cerebral blood flow. (wikipedia.org)
  • Stimulation of chemoreceptors did not increase cerebral blood flow or produce significant redistribution of cerebral blood flow, even though the chemoreflex was intact in these animals (as manifested by vasoconstriction in muscle, kidney, and small bowel) and the cerebral vessels dilated in response to systemic hypercapnia. (ahajournals.org)
  • By so doing, participants increase cerebral blood flow to a specified region of the brain, consequently increasing brain activity and performance on tasks involving that region of the brain. (wikipedia.org)
  • Regional cerebral blood flow, white matter abnormalities, and cerebrospinal fluid hydrodynamics in patients with idiopathic adult hydrocephalus syndrome. (bmj.com)
  • Although it is now well documented (6, 8) that pial as well as intracerebral vessels are amply supplied with sympathetic adrenergic nerves which, as shown for pial arteries, fulfill ultra-structural (5) as well as pharmacologic (7) criteria for a true vasomotor innervation, the role of these fibers in the regulation of cerebral blood flow (CBF) remains a subject of considerable controversy. (springer.com)
  • A limited number of studies exist investigating the possible effects of prostacyclin on cerebral vessels in a clinical setting. (biomedcentral.com)
  • Stroke may occur in approximately one third of patients as a result of narrowing of the blood vessels around the brain, following aSAH. (strokecenter.org)
  • their processes project to local blood vessels and also to the subarachnoidal space. (wikipedia.org)
  • In vivo neuroimaging studies can assist in understanding the neural regions involved in energy dysfunction in bipolar disorder via analyzing blood flow and metabolic processes. (frontiersin.org)
  • 2 The neurovascular unit, which acts as a blood-brain barrier (BBB), is one of the major defence mechanisms of the brain and regulates the passage of large molecules to and from the brain to maintain its delicate ionic and metabolic environment. (bmj.com)
  • Neurovascular coupling is the mechanism by which cerebral blood flow is matched to metabolic activity. (wikipedia.org)
  • Therefore, we determined the pattern of regional cerebral perfusion mania patients and using patients with major depressive disorder (MDD) as positive controls and healthy participants as negative controls. (frontiersin.org)
  • In five patients undergoing cerebral CT survey, one section level was imaged at 120 kVp and 80 kVp, before and after IV administration of iodinated contrast material. (ajnr.org)
  • For each of our five patients, we had four cerebral CT sections: native 80 kVp (number 2, Fig 1C ) and 120 kVp (number 1, Fig 1A ), and 80 kVp (number 4, Fig 1D ) and 120 kVp (number 3, Fig 1B ) after contrast enhancement. (ajnr.org)
  • Twelve stable xenon CT and perfusion CT cerebral examinations were performed within an interval of a few minutes in patients with various cerebrovascular diseases. (ajnr.org)
  • Although the presenile subjects had more severe neuropsychological abnormalities in all realms of cognitive function, including language, and showed greater reductions in regional blood flow than the older patients, they were also more severely demented, thus complicating interpretation of the results. (jamanetwork.com)
  • Two indexes of cerebral perfusion, a ratio of regional flow compared with occipital flow and a left-right asymmetry index, demonstrated relative left frontal hypoperfusion in presenile- but not senile-onset patients and did not appear to be an artifact of the severity differences. (jamanetwork.com)
  • Acetazolamide-enhanced quantitative regional cerebral blood flow studies were performed preoperatively in 35 patients to determine if patterns of vasoreactivity could be identified that might be markers for postoperative morbidity. (elsevier.com)
  • These findings call into question traditional theories of AVM-related hemodynamic decompensation and suggest unique smooth muscle derangements in cerebral vasculature in some AVM patients. (elsevier.com)
  • Five patients with normal CBF tomograms on admission developed delayed neurological deficits in the 2nd week after hemorrhage, at which time repeat CBF tomograms in 4 patients revealed large areas of well defined regional flow decrease in the vascular territories of the anterior or middle cerebral arteries. (elsevier.com)
  • By stimulating these neurons, we aim to investigate whether it is possible to improve the blood flow around brain and ultimately prevent strokes in patients following subarachnoid haemorrhage. (strokecenter.org)
  • The patients were studied by CT and regional cerebral blood flow as well. (arctichealth.org)
  • In Brain and Blood Flow , R. W. Ross Russell, ed. (springer.com)
  • Monitoring of partial pressure of brain tissue oxygen (PbtO 2 ) is suitable for detecting focal changes in cerebral oxy-genation pattern [13]. (springer.com)
  • A detailed examination of the regional distribution of cerebral blood flow revealed that almost all brain regions were hyperperfused during diving. (biologists.org)
  • Because some brain regions did not increase flow significantly during diving, these results suggest that not all brain regions participate equally in the global cerebrovascular response to diving. (biologists.org)
  • have observed that the brain advanced function is related to the changes in the cerebral blood flow perfusion, and that both cerebral blood flow and blood flow velocity in certain regions will change when human emotion is changed ( 4 ). (frontiersin.org)
  • Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. (nii.ac.jp)
  • Single-photon emission tomography (SPET) was used to measure regional brain perfusion using technetium-99m labelled ethyl cysteinate dimer (ECD). (ugent.be)
  • Importantly, despite a decreased cardiac output, relative blood flow to the head increased during diving, suggesting that there is maintenance of blood flow to the brain. (usask.ca)
  • The effects of two levels of fluid-percussion brain injury on cerebral blood flow (CBF) and pial arteriolar diameter were investigated in cats. (utmb.edu)
  • Kontos, H. A. / Effects of fluid-percussion brain injury on regional cerebral blood flow and pial arteriolar diameter . (utmb.edu)
  • Background In the graph theoretical analysis of anatomical brain connectivity, the white matter connections between regions of the brain are identified and serve as basis for the assessment of regional connectivity profiles, for example, to locate the hubs of the brain. (mpg.de)
  • Aneurysmal subarachnoid hemorrhage (aSAH) is bleeding around the under surface of the brain caused by rupture of an aneurysm arising from a blood vessel. (strokecenter.org)
  • One theory as to why this may happen is because bleeding around the base of the brain damages particular cells (neurons) that control blood flow around the rest of the brain. (strokecenter.org)
  • We predict that by increasing the amount of Ach in these neurons, donepezil may improve blood flow to the brain, reducing the chance of developing stroke. (strokecenter.org)
  • All trial participants will have a Xenon CT scan under GA to assess brain blood flow prior to having treatment of their aneurysm. (strokecenter.org)
  • He was married to Edda Sveinsdottir who as a computer scientist helped with the development of the (at that time) advanced computer technology for image construction of the regional brain measurements. (wikipedia.org)
  • The ependymal cells of the SCO are also involved in the production of brain transthyretin, a protein involved in the transport of thyroid hormones in blood. (wikipedia.org)
  • All capillaries in the central nervous system with a functional blood-brain barrier express glucose transporters (GLUT1). (wikipedia.org)
  • The studies described in this Thesis were designed to investigate the patterns of cerebral blood flow (CBF) deficits that occur in Dementia of the Alzheimer Type (DAT) and relate them to performance on a variety of cognitive tasks. (gla.ac.uk)
  • Cerebral blood flow (CBF) alterations after asphyxial cardiac arrest (CA) are not defined in developmental animal models or humans. (nih.gov)
  • Knowledge of cerebral blood flow (CBF) alterations in cases of acute stroke could be valuable in the early management of these cases. (ajnr.org)
  • Among imaging techniques affording evaluation of cerebral perfusion, perfusion CT studies involve sequential acquisition of cerebral CT sections obtained in an axial mode during the IV administration of iodinated contrast material. (ajnr.org)
  • A spiral-based FAIR sequence was used for the acquisition of cerebral blood flow (CBF) maps. (elsevier.com)
  • 1 2 3 4 However, conflicting data regarding the accuracy of this method were recently presented by Harris and Bailey, 5 indicating that hypercapnia induced during general anesthesia made a very small increase in rSO 2 despite the more than doubling of the middle cerebral artery flow velocity. (ahajournals.org)
  • Surprisingly, very little is known about how such visual deprivation impacts regional cerebral blood flow velocity (CBFv) or its adaptation with the underlying neuronal activity (i.e., neurovascular coupling). (arvojournals.org)
  • Regional cerebral oxygen supply and utilization in dementia. (springer.com)
  • Effects of sevoflurane, propofol, and adjunct nitrous oxide on regional cerebral blood flow, oxygen consumption, and blood volume in humans. (nih.gov)
  • S+N especially reduced the oxygen extraction fraction, suggesting disturbed flow-activity coupling in humans at a moderate depth of anesthesia. (nih.gov)
  • The resting state fMRI BOLD (blood-oxygen-level-dependent) signal will be evaluated for 'Goodness-of-Fit' to the default mode network at Baseline, 1 week, and 6 and 12 months in AD participants and normal control participants. (clinicaltrials.gov)
  • COMT activity influences the functional connectivity of the PFC at rest, as well as its activity during task performance, determined using blood oxygen level-dependent (BOLD) fMRI. (ox.ac.uk)
  • Functional neuroimaging studies have pointed to a possible role of cerebral circuits involving the prefrontal and anterior cingulate cortices, the striatum, and thalamus in the pathophysiology of obsessive-compulsive disorder (OCD). (unicamp.br)
  • Our data demonstrate that lower COMT activity is associated with lower cerebral blood flow, although the regions affected differ between those affected by genotype compared with those altered by acute pharmacological inhibition. (ox.ac.uk)
  • Biphasic responses were seen in several structures manifest as increased blood flow at 0.1 mg/kg and a decrease or no effect at the mid doses only to increase again after the two highest doses. (aspetjournals.org)
  • Although exercising skeletal muscle was shown to modify the peripheral distribution of blood flow during diving, the brain's share of cardiac output increases primarily due to a decrease in cerebrovascular resistance. (usask.ca)
  • The purpose of this study was to test the hypothesis that old age results in an increase in vascular resistance and, correspondingly, a decrease in blood flow to ocular, regional cerebral, and spinal tissue in the rat. (uky.edu)
  • Tyramine-induced contraction of the isolated middle cerebral artery of the cat. (springer.com)
  • Present indications for a thrombolytic therapy rely on the time interval between the beginning of symptoms (inferior or superior to 3 hr) and the native cerebral CT findings (5, 9, 10) . (ajnr.org)
  • These findings suggest the need for additional, larger studies to investigate the effects of acetylcholinesterase inhibitors on regional cerebral blood flow. (springer.com)
  • In one patient the conventional x-ray tomogram was negative, while the flow tomogram clearly showed a decreased flow in consonance with the clinical findings. (forskningsdatabasen.dk)
  • Our findings also highlight the importance of considering vascular effects in functional neuroimaging studies, and of exercising caution in ascribing group differences in BOLD signal solely to altered neuronal activity if information about regional perfusion is not available. (ox.ac.uk)
  • Global hemispheric and regional cerebral blood flow (CBF) at baseline and after return of spontaneous circulation (ROSC). (nih.gov)
  • Assessment of intermittent UMTS electromagnetic field effects on blood circulation in the human auditory region using a near-infrared system. (emf-portal.org)
  • Assessment of potential short-term effects of intermittent UMTS electromagnetic fields on blood circulation in an exploratory study, using near-infrared imaging. (emf-portal.org)
  • Dopamine has direct and complex vasoactive effects on cerebral circulation. (ox.ac.uk)
  • In other studies in anesthetized, ventilated dogs and rhesus monkeys, cerebral vasodilator responses to systemic hypoxemia were observed before and after denervation of carotid and aortic chemoreceptors. (ahajournals.org)
  • Flow in these regions of interest was again quantitated after the administration of acetazolamide, a known cerebral vasodilator. (elsevier.com)
  • After the native cerebral CT examination, one section level through the basal nuclei was selected and imaged at 120 kVp (number 1) and 80 kVp (number 2). (ajnr.org)
  • Effect of stimulation of carotid chemoreceptors on total and regional cerebral blood flow. (ahajournals.org)
  • We conclude that stimulation of carotid chemoreceptors does not produce cerebral vasodilation and that chemoreceptors do not contribute significantly to cerebral vasodilation during systemic hypoxemia. (ahajournals.org)
  • Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease. (ox.ac.uk)
  • Optimal recovery of cerebral blood flow (CBF) has been implicated as a critical factor in determining neuronal survival after asphyxial cardiac arrest (CA) in infants and children. (pubmedcentralcanada.ca)
  • A previous study restricted to "handset-like" radiofrequency electromagnetic fields ( publication 9345 ) revealed increased relative regional cerebral blood flow in the dorsolateral prefrontal cortex ipsilateral to the side of exposure . (emf-portal.org)
  • Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. (semanticscholar.org)
  • Our hypothesis is that damage to these neurons may prevent the production of ACh, which then causes reduced blood flow and stroke if left untreated. (strokecenter.org)
  • Fourteen NaI-collimated scintillation probes were applied over each cerebral hemisphere. (ahajournals.org)
  • Cerebral perfusion in SW was significantly decreased in the cuneus, fusiform/parahippocampal gyri, and cerebellum of the right hemisphere, while it was increased in the inferior occipital gyrus of the left hemisphere. (bvsalud.org)
  • BBB was impermeable to gadoteridol 150 mins after CA. CBF in the 12-min CA group was blood pressure passive at 60 min assessed via infusion of epinephrine. (nih.gov)
  • Lennihan L, Mayer S, Fink ME, et al (2000) Effect of hypervolemic therapy on cerebral blood flow after subarachnoid hemorrhage. (springer.com)
  • Subarachnoid hemorrhage (SAH) was induced in 13 adult mongrel cats by a slow injection of fresh autogenous blood into the cisterna magna. (thejns.org)
  • However, lesions of the amygdala in humans rarely produce the constellation of emotional abnormalities associated with lesions of the amygdala in nonhuman primates, except when amygdala damage occurs in conjunction with diffuse cerebral disease ( 9 ). (pnas.org)
  • Until the development of the blood flow tracer HMPAO (hexamethylpropyleneamine oxime) there was no practical way to study regional cerebral blood flow during or soon after seizures. (gla.ac.uk)
  • To study the effects of radiofrequency electromagnetic fields similar to those emitted by mobile phones on waking 1regional cerebral blood flow in healthy young men. (emf-portal.org)
  • In the present study, the effect of a " base station -like" signal (mimicked the signal modulation emitted by a GSM base station ) on regional blood flow was investigated and compared with a "handset-like" signal (similar spectral content as the one emitted by GSM mobile phones ). (emf-portal.org)
  • Effects of a 902 MHz mobile phone on cerebral blood flow in humans: a PET study. (emf-portal.org)
  • The current study sought to investigate the effects of short-term (two-hour) visual deprivation on regional CBFv and neurovascular coupling. (arvojournals.org)
  • A rapidly rotating single-photon emission tomograph was used to study regional cerebral blood flow by 133Xenon inhalation. (forskningsdatabasen.dk)
  • A regional cerebral blood flow study. (wikigenes.org)
  • The limitations of the available techniques encourage the development of a practical method for measuring regional cerebral perfusion non invasively in different vascular territories. (springer.com)
  • After decades of work with various biofeedback mechanisms, Toomim accidentally stumbled upon conscious control of cerebral blood flow in 1994. (wikipedia.org)
  • Regional cerebral rate of glucose consumption, MRglc, as assessed by FDG-PET will be measured at Baseline in (Part I) and at 12 months in (Part II), in AD participants and normal control participants. (clinicaltrials.gov)
  • Circadian and homeostatic modulation of functional connectivity and regional cerebral blood flow in humans under normal entrained conditions. (sigmaaldrich.com)
  • They speculated that external carotid flow might severely affect the results of NIRS. (ahajournals.org)
  • In anesthetized and ventilated dogs, carotid chemoreceptors were stimulated with nicotine or hypoxic and hypercapnic blood. (ahajournals.org)