Regional blood flow. Medical search

The flow of BLOOD through or around an organ or region of the body.

Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.

A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.

The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).

The circulation of blood through the BLOOD VESSELS of the BRAIN.

The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.

The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.

The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.

The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)

The circulation of blood through the CORONARY VESSELS of the HEART.

The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.

PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.

Scandium. An element of the rare earth family of metals. It has the atomic symbol Sc, atomic number 21, and atomic weight 45.

The circulation of the BLOOD through the vessels of the KIDNEY.

The circulation of BLOOD through the LIVER.

The circulation of the BLOOD through the LUNGS.

A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.

Unstable isotopes of xenon that decay or disintegrate emitting radiation. Xe atoms with atomic weights 121-123, 125, 127, 133, 135, 137-145 are radioactive xenon isotopes.

The number of times the HEART VENTRICLES contract per unit of time, usually per minute.

A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.

Measurement of oxygen and carbon dioxide in the blood.

Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.

The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)

Unstable isotopes of nitrogen that decay or disintegrate emitting radiation. N atoms with atomic weights 12, 13, 16, 17, and 18 are radioactive nitrogen isotopes.

Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.

A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

The ratio of alveolar ventilation to simultaneous alveolar capillary blood flow in any part of the lung. (Stedman, 25th ed)

Unstable isotopes of oxygen that decay or disintegrate emitting radiation. O atoms with atomic weights 13, 14, 15, 19, and 20 are radioactive oxygen isotopes.

Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.

The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).

Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)

A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.

The circulation of the BLOOD through the MICROVASCULAR NETWORK.

Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.

The placing of a body or a part thereof into a liquid.

The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.

The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.

Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.

Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.

A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.

A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.

The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.

Drugs used to cause dilation of the blood vessels.

The posture of an individual lying face up.

Anesthesia caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.

Elements of limited time intervals, contributing to particular results or situations.

A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.

The hollow, muscular organ that maintains the circulation of the blood.

Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.

The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.

A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

The inferior part of the lower extremity between the KNEE and the ANKLE.

The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

Arteries which arise from the abdominal aorta and distribute to most of the intestines.

The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)

Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.

A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.

Part of the arm in humans and primates extending from the ELBOW to the WRIST.

The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.

A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.

Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.

A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.

Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.

Injections made into a vein for therapeutic or experimental purposes.

An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.

Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

The relationship between the dose of an administered drug and the response of the organism to the drug.

The veins and arteries of the HEART.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.

The vessels carrying blood away from the heart.

Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.

Contractile activity of the MYOCARDIUM.

The minute vessels that connect the arterioles and venules.

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.

Relatively complete absence of oxygen in one or more tissues.

The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)

A noble gas with the atomic symbol Xe, atomic number 54, and atomic weight 131.30. It is found in the earth's atmosphere and has been used as an anesthetic.

The change in gene frequency in a population due to migration of gametes or individuals (ANIMAL MIGRATION) across population barriers. In contrast, in GENETIC DRIFT the cause of gene frequency changes are not a result of population or gamete movement.

Determination of the shortest time interval between the injection of a substance in the vein and its arrival at some distant site in sufficient concentration to produce a recognizable end result. It represents approximately the inverse of the average velocity of blood flow between two points.

Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.

Recording of change in the size of a part as modified by the circulation in it.

The position or attitude of the body.

The arterial blood vessels supplying the CEREBRUM.

Substances used to allow enhanced visualization of tissues.

A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.

The blood vessels which supply and drain the RETINA.

An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Treatment process involving the injection of fluid into an organ or tissue.

The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.

The TEMPERATURE at the outer surface of the body.

The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.

The main artery of the thigh, a continuation of the external iliac artery.

Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.

Intrarenal site of action of calcium on renin secretion in dogs. (1/9283)

We studied the effects of intrarenal calcium infusion on renin secretion in sodium-depleted dogs in an attempt to elucidate the major site of calcium-induced inhibition of renin release. Both calcium chloride and calcium gluconate reduced renal blood flow and renin secretion while renal perfusion pressure was unchanged. These data indicate that calcium inhibition of renin secretion did not occur primarily at the renal vascular receptor; decreased renal blood flow is usually associated with increased renin secretion. Calcium chloride infusion increased urinary chloride excretion without affecting sodium excretion, and calcium gluconate failed to increase either sodium or chloride excretion. Also, the filtered loads of sodium and chloride were unchanged during the calcium infusions. These results give no indication that calcium inhibited renin secretion by increasing the sodium or chloride load at the macula densa. The effects of intrarenal calcium infusion on renin release were also assessed in dogs with a nonfiltering kidney in which renal tubular mechanisms could not influence renin secretion. The observation that calcium still suppressed renin release in these dogs provides additional evidence that the the major effect of calcium involved nontubular mechanisms. Thus, it appears likely that calcium acted directly on the juxtaglomerular cells to inhibit renin secretion. (+info)

Vascular remodeling in response to altered blood flow is mediated by fibroblast growth factor-2. (2/9283)

Vascular structures adapt to changes in blood flow by adjusting their diameter accordingly. The factors mediating this process are only beginning to be identified. We have recently established a mouse model of arterial remodeling in which flow in the common carotid artery is interrupted by ligation of the vessel near the carotid bifurcation, resulting in a dramatic reduction in vessel diameter as a consequence of inward remodeling and intimal lesion formation. In the present study, we used this model to determine the role of fibroblast growth factor-2 (FGF-2) in the remodeling response by maintaining neutralizing serum levels of a mouse monoclonal antibody against FGF-2 for 4 weeks. Morphometric analysis revealed that intimal lesion formation was not affected by the antibody. However, lumen narrowing was significantly inhibited, resulting in a greater than 3-fold increase in lumen area in anti-FGF-2-treated animals compared with controls. Treatment with anti-FGF-2 antibody significantly inhibited the reduction in vessel diameter (inward remodeling) and shortening of the internal elastic lamina in the ligated vessel. In addition, anti-FGF-2 treatment also caused outward remodeling of the contralateral carotid artery. These findings identify FGF-2 as an important factor in vascular remodeling, and its effects are likely to be mediated by increasing vascular tone. The results are consistent with the recent observation of reduced vascular tone in the FGF-2-deficient mouse. (+info)

Role of endothelin in the increased vascular tone of patients with essential hypertension. (3/9283)

We investigated the possible role of endothelin in the increased vasoconstrictor tone of hypertensive patients using antagonists of endothelin receptors. Forearm blood flow (FBF) responses (strain-gauge plethysmography) to intraarterial infusion of blockers of endothelin-A (ETA) (BQ-123) and endothelin-B (ETB) (BQ-788) receptors, separately and in combination, were measured in hypertensive patients and normotensive control subjects. In healthy subjects, BQ-123 alone or in combination with BQ-788 did not significantly modify FBF (P=0.78 and P=0.63, respectively). In hypertensive patients, in contrast, BQ-123 increased FBF by 33+/-7% (P<0.001 versus baseline), and the combination of BQ-123 and BQ-788 resulted in a greater vasodilator response (63+/-12%; P=0.006 versus BQ-123 alone in the same subjects). BQ-788 produced a divergent vasoactive effect in the two groups, with a decrease of FBF (17+/-5%; P=0.004 versus baseline) in control subjects and transient vasodilation (15+/-7% after 20 minutes) in hypertensive patients (P<0.001, hypertensives versus controls). The vasoconstrictor response to endothelin-1 was slightly higher (P=0.04) in hypertensive patients (46+/-4%) than in control subjects (32+/-4%). Our data indicate that patients with essential hypertension have increased vascular endothelin activity, which may be of pathophysiological relevance to their increased vascular tone. In these patients, nonselective ETA and ETB blockade seems to produce a greater vasodilator effect than selective ETA blockade. (+info)

Bronchial artery perfusion scintigraphy to assess bronchial artery blood flow after lung transplantation. (4/9283)

The bronchial arterial system is inevitably interrupted in transplanted lungs when removing the organs from the donor, but it can be reestablished by direct bronchial artery revascularization (BAR) during implantation. The purpose of this study was to visualize and quantify the distribution of bronchial artery perfusion after en bloc double lung transplantation with BAR, by injecting radiolabeled macroaggregated albumin directly into the bronchial artery system. METHODS: BAR was performed using the internal mammary artery as conduit. Patients were imaged 1 mo (n = 13) or 2 y (n = 9) after en bloc double lung transplantation with BAR. Immediately after bronchial arteriography, 100 MBq macroaggregated albumin (45,000 particles) were injected through the arteriographic catheter. Gamma camera studies were then acquired in the anterior position. At the end of imaging, with the patient remaining in exactly the same position, 81mKr-ventilation scintigraphy or conventional intravenous pulmonary perfusion scintigraphy or both were performed. Images were evaluated by visual analysis, and a semiquantitative assessment of the bronchial arterial supply to the peripheral parts of the lungs was obtained with conventional pulmonary scintigraphy. RESULTS: The bronchial artery scintigraphic images showed that the major part of the bronchial arterial flow supplied central thoracic structures, but bronchial artery perfusion could also be demonstrated in the peripheral parts of the lungs when compared with conventional pulmonary scintigraphy. There were no differences between scintigrams obtained from patients studied 1 mo and 2 y post-transplantation. CONCLUSION: Total distribution of bronchial artery supply to the human lung has been visualized in lung transplant patients. This study demonstrates that this nutritive flow reaches even the most peripheral parts of the lungs and is present 1 mo as well as 2 y after lung transplantation. The results suggest that bronchial artery revascularization may be of significance for the long-term status of the lung transplant. (+info)

Pulsed Doppler ultrasonographic evaluation of portal blood flow in dogs with experimental portal vein branch ligation. (5/9283)

Portal blood flow was measured using pulsed Doppler ultrasound in 6 dogs before and after left portal vein branch ligation. Mean portal vein blood flow velocity and mean portal vein blood flow were significantly reduced after ligation and the congestion index was increased (p < 0.01). Pulsed Doppler ultrasound studies provide valuable physiological information which may assist the clinician with the diagnosis of canine hepatic circulatory disorders. (+info)

Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. (6/9283)

Diabetes is a major risk factor for coronary and peripheral artery diseases. Although diabetic patients often present with advanced forms of these diseases, it is not known whether the compensatory mechanisms to vascular ischemia are affected in this condition. Accordingly, we sought to determine whether diabetes could: 1) impair the development of new collateral vessel formation in response to tissue ischemia and 2) inhibit cytokine-induced therapeutic neovascularization. Hindlimb ischemia was created by femoral artery ligation in nonobese diabetic mice (NOD mice, n = 20) and in control C57 mice (n = 20). Hindlimb perfusion was evaluated by serial laser Doppler studies after the surgery. In NOD mice, measurement of the Doppler flow ratio between the ischemic and the normal limb indicated that restoration of perfusion in the ischemic hindlimb was significantly impaired. At day 14 after surgery, Doppler flow ratio in the NOD mice was 0.49+/-0.04 versus 0.73+/-0.06 for the C57 mice (P< or =0.005). This impairment in blood flow recovery persisted throughout the duration of the study with Doppler flow ratio values at day 35 of 0.50+/-0.05 versus 0.90+/-0.07 in the NOD and C57 mice, respectively (P< or =0.001). CD31 immunostaining confirmed the laser Doppler data by showing a significant reduction in capillary density in the NOD mice at 35 days after surgery (302+/-4 capillaries/mm2 versus 782+/-78 in C57 mice (P< or =0.005). The reduction in neovascularization in the NOD mice was the result of a lower level of vascular endothelial growth factor (VEGF) in the ischemic tissues, as assessed by Northern blot, Western blot and immunohistochemistry. The central role of VEGF was confirmed by showing that normal levels of neovascularization (compared with C57) could be achieved in NOD mice that had been supplemented for this growth factor via intramuscular injection of an adenoviral vector encoding for VEGF. We conclude that 1) diabetes impairs endogenous neovascularization of ischemic tissues; 2) the impairment in new blood vessel formation results from reduced expression of VEGF; and 3) cytokine supplementation achieved by intramuscular adeno-VEGF gene transfer restores neovascularization in a mouse model of diabetes. (+info)

Sonographic evidence for the involvement of the utero-ovarian counter-current system in the ovarian control of directed uterine sperm transport. (7/9283)

Sperm transport from the cervix into the tube is an important uterine function within the process of reproduction. This function is exerted by uterine peristalsis and is controlled by the dominant ovarian structure via a cascade of endocrine events. The uterine peristaltic activity involves only the stratum subvasculare of the myometrium, which exhibits a predominantly circular arrangement of muscular fibres that separate at the fundal level into the fibres of the cornua and continue into the circular muscles of the respective tubes. Since spermatozoa are transported preferentially into the tube ipsilateral to the dominant follicle, this asymmetric uterine function may be controlled by the ovary via direct effects utilizing the utero-ovarian counter-current system, in addition to the systemic circulation. To test this possibility the sonographic characteristics of the uterine vascular bed were studied during different phases of the menstrual cycle. Vaginal sonography with the measurement of Doppler flow characteristics of both uterine arteries and of the arterial anastomoses of the uterine and ovarian arteries (junctional vessels) in the cornual region of both sides of the uterus during the menstrual phase of regular-cycling women demonstrated significant lower resistance indices of the junctional vessels ipsilateral to the side of the dominant ovarian structure as compared with the corresponding arteries contralaterally. By the use of the perfusion mode technique, it could be observed that vascular perfusion of the fundal myometrium was significantly increased ipsilateral to the dominant follicle during the late follicular phase of the cycle. These results show that the endocrine control of the dominant ovarian structure over uterine function is not only exerted via the systemic circulation but also directly, most probably utilizing the utero-ovarian counter-current system. (+info)

Endothelial function in Marfan syndrome: selective impairment of flow-mediated vasodilation. (8/9283)

BACKGROUND: The cardiovascular complications of Marfan syndrome arise due to alterations in the structural and functional properties of fibrillin, a constituent of vascular connective tissues. Fibrillin-containing microfibrils are closely associated with arterial endothelial cells, indicating a possible functional role for fibrillin in the endothelium. Plasma concentrations of endothelial cell products are elevated in Marfan subjects, which indirectly indicates endothelial dysfunction. This study directly assessed flow- and agonist-mediated endothelium-dependent brachial artery reactivity in Marfan subjects. METHODS AND RESULTS: In 20 Marfan and 20 control subjects, brachial artery diameter, blood flow, and blood pressure were measured by ultrasonic wall tracking, Doppler ultrasound, and photoplethysmography, respectively. Measurements were taken during hand hyperemia (a stimulus for endothelium-derived nitric oxide [NO] release in the upstream brachial artery) and after sublingual administration of the endothelium-independent vasodilator nitroglycerin. In 9 Marfan and 6 control subjects, the above parameters were also assessed during intra-arterial infusions of acetylcholine and bradykinin (agonists that stimulate NO production) and NG-monomethyl-L-arginine (L-NMMA, an inhibitor of NO production). Flow-mediated responses differed markedly between Marfan and control subjects (-1.6+/-3.5% versus 6. 50+/-4.1%, respectively; P<0.0001), whereas nitroglycerin produced similar vasodilation (14.2+/-5.7% versus 15.2+/-7.8%; P=NS). Agonist-induced vasodilation to incremental intra-arterial infusions of acetylcholine and bradykinin were not significantly different between Marfan and control subjects, and intra-arterial L-NMMA produced similar reductions in brachial artery diameter in both groups. CONCLUSIONS: These data demonstrate impaired flow-mediated but preserved agonist-mediated endothelium-dependent vasodilation in Marfan subjects and suggest preservation of basal NO release. Selective loss of flow-mediated dilation suggests a role for fibrillin in endothelial cell mechanotransduction. (+info)

There are several types of ischemia, including:

1. Myocardial ischemia: Reduced blood flow to the heart muscle, which can lead to chest pain or a heart attack.
2. Cerebral ischemia: Reduced blood flow to the brain, which can lead to stroke or cognitive impairment.
3. Peripheral arterial ischemia: Reduced blood flow to the legs and arms.
4. Renal ischemia: Reduced blood flow to the kidneys.
5. Hepatic ischemia: Reduced blood flow to the liver.

Ischemia can be diagnosed through a variety of tests, including electrocardiograms (ECGs), stress tests, and imaging studies such as CT or MRI scans. Treatment for ischemia depends on the underlying cause and may include medications, lifestyle changes, or surgical interventions.

1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.

2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.

3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.

4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.

5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.

6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.

7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.

8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.

9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.

10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.

There are different types of myocardial infarctions, including:

1. ST-segment elevation myocardial infarction (STEMI): This is the most severe type of heart attack, where a large area of the heart muscle is damaged. It is characterized by a specific pattern on an electrocardiogram (ECG) called the ST segment.
2. Non-ST-segment elevation myocardial infarction (NSTEMI): This type of heart attack is less severe than STEMI, and the damage to the heart muscle may not be as extensive. It is characterized by a smaller area of damage or a different pattern on an ECG.
3. Incomplete myocardial infarction: This type of heart attack is when there is some damage to the heart muscle but not a complete blockage of blood flow.
4. Collateral circulation myocardial infarction: This type of heart attack occurs when there are existing collateral vessels that bypass the blocked coronary artery, which reduces the amount of damage to the heart muscle.

Symptoms of a myocardial infarction can include chest pain or discomfort, shortness of breath, lightheadedness, and fatigue. These symptoms may be accompanied by anxiety, fear, and a sense of impending doom. In some cases, there may be no noticeable symptoms at all.

Diagnosis of myocardial infarction is typically made based on a combination of physical examination findings, medical history, and diagnostic tests such as an electrocardiogram (ECG), cardiac enzyme tests, and imaging studies like echocardiography or cardiac magnetic resonance imaging.

Treatment of myocardial infarction usually involves medications to relieve pain, reduce the amount of work the heart has to do, and prevent further damage to the heart muscle. These may include aspirin, beta blockers, ACE inhibitors or angiotensin receptor blockers, and statins. In some cases, a procedure such as angioplasty or coronary artery bypass surgery may be necessary to restore blood flow to the affected area.

Prevention of myocardial infarction involves managing risk factors such as high blood pressure, high cholesterol, smoking, diabetes, and obesity. This can include lifestyle changes such as a healthy diet, regular exercise, and stress reduction, as well as medications to control these conditions. Early detection and treatment of heart disease can help prevent myocardial infarction from occurring in the first place.

Coronary disease is often caused by a combination of genetic and lifestyle factors, such as high blood pressure, high cholesterol levels, smoking, obesity, and a lack of physical activity. It can also be triggered by other medical conditions, such as diabetes and kidney disease.

The symptoms of coronary disease can vary depending on the severity of the condition, but may include:

* Chest pain or discomfort (angina)
* Shortness of breath
* Fatigue
* Swelling of the legs and feet
* Pain in the arms and back

Coronary disease is typically diagnosed through a combination of physical examination, medical history, and diagnostic tests such as electrocardiograms (ECGs), stress tests, and cardiac imaging. Treatment for coronary disease may include lifestyle changes, medications to control symptoms, and surgical procedures such as angioplasty or bypass surgery to improve blood flow to the heart.

Preventative measures for coronary disease include:

* Maintaining a healthy diet and exercise routine
* Quitting smoking and limiting alcohol consumption
* Managing high blood pressure, high cholesterol levels, and other underlying medical conditions
* Reducing stress through relaxation techniques or therapy.

There are different types of anoxia, including:

1. Cerebral anoxia: This occurs when the brain does not receive enough oxygen, leading to cognitive impairment, confusion, and loss of consciousness.
2. Pulmonary anoxia: This occurs when the lungs do not receive enough oxygen, leading to shortness of breath, coughing, and chest pain.
3. Cardiac anoxia: This occurs when the heart does not receive enough oxygen, leading to cardiac arrest and potentially death.
4. Global anoxia: This is a complete lack of oxygen to the entire body, leading to widespread tissue damage and death.

Treatment for anoxia depends on the underlying cause and the severity of the condition. In some cases, hospitalization may be necessary to provide oxygen therapy, pain management, and other supportive care. In severe cases, anoxia can lead to long-term disability or death.

Prevention of anoxia is important, and this includes managing underlying medical conditions such as heart disease, diabetes, and respiratory problems. It also involves avoiding activities that can lead to oxygen deprivation, such as scuba diving or high-altitude climbing, without proper training and equipment.

In summary, anoxia is a serious medical condition that occurs when there is a lack of oxygen in the body or specific tissues or organs. It can cause cell death and tissue damage, leading to serious health complications and even death if left untreated. Early diagnosis and treatment are crucial to prevent long-term disability or death.

In some cases, hyperemia can be a sign of a more serious underlying condition that requires medical attention. For example, if hyperemia is caused by an inflammatory or infectious process, it may lead to tissue damage or organ dysfunction if left untreated.

Hyperemia can occur in various parts of the body, including the skin, muscles, organs, and other tissues. It is often diagnosed through physical examination and imaging tests such as ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI). Treatment for hyperemia depends on its underlying cause, and may include antibiotics, anti-inflammatory medications, or surgery.

In the context of dermatology, hyperemia is often used to describe a condition called erythema, which is characterized by redness and swelling of the skin due to increased blood flow. Erythema can be caused by various factors, such as sun exposure, allergic reactions, or skin infections. Treatment for erythema may include topical medications, oral medications, or other therapies depending on its underlying cause.

The term ischemia refers to the reduction of blood flow, and it is often used interchangeably with the term stroke. However, not all strokes are caused by ischemia, as some can be caused by other factors such as bleeding in the brain. Ischemic stroke accounts for about 87% of all strokes.

There are different types of brain ischemia, including:

1. Cerebral ischemia: This refers to the reduction of blood flow to the cerebrum, which is the largest part of the brain and responsible for higher cognitive functions such as thought, emotion, and voluntary movement.
2. Cerebellar ischemia: This refers to the reduction of blood flow to the cerebellum, which is responsible for coordinating and regulating movement, balance, and posture.
3. Brainstem ischemia: This refers to the reduction of blood flow to the brainstem, which is responsible for controlling many of the body's automatic functions such as breathing, heart rate, and blood pressure.
4. Territorial ischemia: This refers to the reduction of blood flow to a specific area of the brain, often caused by a blockage in a blood vessel.
5. Global ischemia: This refers to the reduction of blood flow to the entire brain, which can be caused by a cardiac arrest or other systemic conditions.

The symptoms of brain ischemia can vary depending on the location and severity of the condition, but may include:

1. Weakness or paralysis of the face, arm, or leg on one side of the body
2. Difficulty speaking or understanding speech
3. Sudden vision loss or double vision
4. Dizziness or loss of balance
5. Confusion or difficulty with memory
6. Seizures
7. Slurred speech or inability to speak
8. Numbness or tingling sensations in the face, arm, or leg
9. Vision changes, such as blurred vision or loss of peripheral vision
10. Difficulty with coordination and balance.

It is important to seek medical attention immediately if you experience any of these symptoms, as brain ischemia can cause permanent damage or death if left untreated.

Blood Flow Metab. 13 (3): 526-30. doi:10.1038/jcbfm.1993.68. PMID 8478410. "Launch of tablet to make life easier for dogs in ... Huber M, Kittner B, Hojer C, Fink GR, Neveling M, Heiss WD (1993). "Effect of propentofylline on regional cerebral glucose ...

https://en.wikipedia.org/wiki/Propentofylline

In 1965, the first regional Cerebral Blood Flow (rCBF) symposium was held in Lund, Sweden. In March 1980, following discussions ... "History of International Society for Cerebral Blood Flow and Metabolism" (PDF). Journal of Cerebral Blood Flow & Metabolism. 32 ... Technical improvements in the study of cerebral blood flow pioneered by Niels Lassen and David Ingvar in the mid-twentieth ... The Journal of Cerebral Blood Flow & Metabolism has been an important element of the ISCFBM since the organization's founding. ...

https://en.wikipedia.org/wiki/International_Society_for_Cerebral_Blood_Flow_&_Metabolism

Journal of Cerebral Blood Flow and Metabolism. 15 (4): 681-6. doi:10.1038/jcbfm.1995.85. PMID 7790418. Meiniel A (March 2001 ... Rahner-Welsch S, Vogel J, Kuschinsky W (July 1995). "Regional congruence and divergence of glucose transporters (GLUT1) and ... Hypendymal cells and ependymal cells both are secretory in nature; their processes project to local blood vessels and also to ... All capillaries in the central nervous system with a functional blood-brain barrier express glucose transporters (GLUT1). These ...

https://en.wikipedia.org/wiki/Subcommissural_organ

Journal of Cerebral Blood Flow and Metabolism. 9 (6): 786-794. doi:10.1038/jcbfm.1989.112. PMID 2684992. Blin J, Ray CA, Chase ... TN, Piercey MF (1991). "Regional cerebral glucose metabolism compared in rodents and humans". Brain Research. 568 (1-2): 215- ...

https://en.wikipedia.org/wiki/Olney's_lesions

"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... 91092-3. Lassen, Niels A.; Ingvar, David H. (1972). "Radioisotopic assessment of regional cerebral blood flow". Progress in ... There is a Niels Lassen Award presented by the International Society for Cerebral Blood Flow and Metabolism (ISCBFM). ((The ... Olaf B. Paulson (1997). "Niels A. Lassen, M.D., Ph.D.: 1926-1997". Journal of Cerebral Blood Flow & Metabolism. 17 (10): 1005- ...

https://en.wikipedia.org/wiki/Niels_A._Lassen

Kendal, WS (2001). "A stochastic model for the self-similar heterogeneity of regional organ blood flow". Proc Natl Acad Sci U S ... Bassingthwaighte, JB (1989). "Fractal nature of regional myocardial blood flow heterogeneity". Circ Res. 65 (3): 578-590. doi: ... measles epidemiology HIV epidemiology, the geographic clustering of childhood leukemia blood flow heterogeneity the genomic ...

https://en.wikipedia.org/wiki/Taylor's_law

Ball, RH; Espinoza, MI; Parer, JT (1994). "Regional blood flow in asphyxiated fetuses with seizures". Am J Obstet Gynecol. 170 ...

https://en.wikipedia.org/wiki/Montevideo_units

"Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): 1173-1197. doi:10.1093/ ...

https://en.wikipedia.org/wiki/Prefrontal_synthesis

Paradis, G R; Kelly, P J (1975-03-01). "Blood flow and mineral deposition in canine tibial fractures". The Journal of Bone and ... Due to regional acceleratory phenomenon, repeated biopsies of the same bone may perturb the data being gathered. Transient RAP ... Regional acceleratory phenomenon (RAP) is a sudden acceleration of normal tissue processes in reaction to noxious stimuli. It ... The effects of regional acceleratory phenomenon can be positive or negative. A study in rabbits suggested that, following ...

https://en.wikipedia.org/wiki/Regional_Acceleratory_Phenomenon

Gk, Frank; Wh, Kaye; P, Greer; Cc, Meltzer; Jc, Price (November 20, 2000). "Regional Cerebral Blood Flow After Recovery From ... J Cereb Blood Flow Metab 2007 27:1533-1539. PMID 17519979. Lois C, Gonzalez I, Johnson KA, Price JC. PET imaging of tau protein ... Price is also on the publication committee for the Journal of Cerebral Blood Flow and Metabolism, a leading journal in the ... Meltzer at Pittsburgh to assess whether cerebral blood flow (CBF) is reduced in aging. That revealed no decrease in CBF after ...

https://en.wikipedia.org/wiki/Julie_C._Price

"Mechanically restricted regional blood flow might explain gastrointestinal pain". Nature Clinical Practice Gastroenterology & ...

https://en.wikipedia.org/wiki/Hans_Gregersen

During the procedure, the person is under regional or general anesthesia. A surgical tourniquet prevents blood flow to the limb ... Blood tests or imaging studies are not usually necessary. Initial treatment is typically with a cortisone shot into the ... The person is placed under regional anesthesia and a surgical tourniquet is used. The skin is opened with small curved ... Manual workers Alcoholics People with a higher-than-average fasting blood glucose level People with previous hand injury People ...

https://en.wikipedia.org/wiki/Dupuytren's_contracture

"Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 (7): 1173-1197. doi:10.1093/ ... PET studies seem to indicate that there is a correlation between blood flow in the pontine tegmentum and REM sleep Pontine ...

https://en.wikipedia.org/wiki/Pontine_tegmentum

July 1997). "Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study". Brain. 120 ( Pt 7) (7): 1173- ... Hofle N, Paus T, Reutens D, Fiset P, Gotman J, Evans AC, Jones BE (June 1997). "Regional cerebral blood flow changes as a ... NREM sleep is characterized by decreased global and regional cerebral blood flow. It constitutes ~80% of all sleep in adult ... Mazoyer B, Houdé O, Joliot M, Mellet E, Tzourio-Mazoyer N (September 2009). "Regional cerebral blood flow increases during ...

https://en.wikipedia.org/wiki/Neuroscience_of_sleep

"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... Certain techniques such as fMRI image tissues (particularly cerebral tissues) by blood flow and thus show metabolism. Also, ... Lassen NA, Ingvar DH, Skinhøj E (October 1978). "Brain Function and Blood Flow". Scientific American. 239 (4): 62-71. Bibcode: ... Some studies require the labeling of a patient's own blood cells with a radionuclide (leukocyte scintigraphy and red blood cell ...

https://en.wikipedia.org/wiki/Nuclear_medicine

"Quantitative determination of regional cerebral blood-flow in man". The Lancet. 278 (7206): 806-807. doi:10.1016/s0140-6736(61) ... Lassen, Niels A.; Ingvar, David H.; Skinhøj, Erik (October 1978). "Brain Function and Blood Flow". Scientific American. 239 (4 ... as well as the flow rates of streams and rivers. In geology, archaeology, and paleontology, natural radionuclides are used to ...

https://en.wikipedia.org/wiki/Radionuclide

"Regional cerebral blood flow through the sleep-wake cycle". Brain. Oxford University Press. 120: 1173-1197. doi:10.1093/brain/ ... Studies detect an increase of blood flow in a specific brain region and then credit that region with a role in generating ... Non-invasive measures of brain activity like electroencephalogram (EEG) voltage averaging or cerebral blood flow cannot ...

https://en.wikipedia.org/wiki/Dream

... controlling blood pressure; and modulating the regional flow of blood to tissues. In performing these roles, eicosanoids most ... blood flow to tissues, and/or blood pressure. However, their function and relevancy to human physiology and pathology have not ... The blood vessels engorge and the injury reddens. Swelling-LTB4 makes the blood vessels more permeable. Plasma leaks out into ... and other blood vessels as well as on the kidney's reabsorption of sodium and water, and act to reduce blood pressure and ...

https://en.wikipedia.org/wiki/Eicosanoid

"Reduced regional cerebral blood flow in non-psychotic violent offenders". Psychiatry Research: Neuroimaging. 98 (1): 29-41. doi ... Reduced Cerebral Blood Flow in Angular Gyrus. A couple of studies found reduced cerebral blood flow in angular gyrus of ... 2011). "Mindfulness practice leads to increases in regional brain gray matter density". Psychiatry Research: Neuroimaging. 191 ...

https://en.wikipedia.org/wiki/Neurocriminology

Fallon BA, Keilp J, Prohovnik I, Heertum RV, Mann JJ (2003). "Regional cerebral blood flow and cognitive deficits in chronic ... history of tick exposure and possibly testing for specific antibodies in the blood. Blood tests are often negative in the early ... If the removed tick is full of blood a single dose of doxycycline may be used to prevent the development of infection but is ... Unlike blood and intrathecal antibody tests, CSF pleocytosis tests revert to normal after infection ends and therefore can be ...

https://en.wikipedia.org/wiki/Lyme_disease

Marion, DW; Darby, J; Yonas, H (1991). "Acute regional cerebral blood flow changes caused by severe head injuries". J Neurosurg ...

https://en.wikipedia.org/wiki/Maudsley_Hospital

Methionine enkephalin as a possible neuromodulator of regional cerebral blood flow. Experientia, 41(7), 932-933. https://doi. ...

https://en.wikipedia.org/wiki/Kenneth_Blum

... but flowing with hotter blood". Hanrahan spoke highly of his time recording with Jack Bruce, saying "with Jack you are spoilt, ... Burke, Jack (11 August 1984). "The Wax Works". The Lake Geneva Regional News. Lake Geneva, Wisconsin. Retrieved 5 December 2020 ... Music reviewer Jack Burke described Exotica in the Lake Geneva Regional News as "soothing and provocative both, ranging far ...

https://en.wikipedia.org/wiki/Exotica_(Kip_Hanrahan_album)

April 2010). "Regional cerebral blood flow changes in female to male gender identity disorder". Psychiatry and Clinical ... to compare the regional cerebral blood flow (rCBF) of 11 gynephilic trans men with that of 9 androphilic cis females. Although ... the study did reveal that the gynephilic trans men showed significant decrease in blood flow in the left anterior cingulate ... Luders E, Sánchez FJ, Gaser C, Toga AW, Narr KL, Hamilton LS, Vilain E (July 2009). "Regional gray matter variation in male-to- ...

https://en.wikipedia.org/wiki/Causes_of_gender_incongruence

Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include ... Collaborators (2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of ... The most concerning short-term adverse effects of stimulants, such as elevated blood pressure and heart rate, waned in long- ...

https://en.wikipedia.org/wiki/Dextroamphetamine

Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... Following absorption into the blood stream, lisdexamfetamine is completely converted by red blood cells to dextroamphetamine ... reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include ... Collaborators (2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of ...

https://en.wikipedia.org/wiki/Amphetamine

Smoking also has a deleterious effect on regional cerebral blood flow (rCBF). The chances of having a stroke increase with the ... "Effects of smoking on regional cerebral blood flow in neurologically normal subjects". Stroke: A Journal of Cerebral ... Transfusion therapy lowers the risk for a new silent stroke in children who have both abnormal cerebral artery blood flow ... The blood cells in sickle cell disease are abnormally shaped (sickle-shaped) and may form clots or block blood vessels. ...

https://en.wikipedia.org/wiki/Silent_stroke

"Deep dyslexia and right hemisphere reading-a regional cerebral blood flow study". Aphasiology. 11 (12): 1139-1158. doi:10.1080/ ...

https://en.wikipedia.org/wiki/Deep_dyslexia

Devous MD, Trivedi MH, Rush AJ (April 2001). "Regional cerebral blood flow response to oral amphetamine challenge in healthy ... Following absorption into the blood stream, lisdexamfetamine is completely converted by red blood cells to dextroamphetamine ... After oral ingestion, lisdexamfetamine is broken down by enzymes in red blood cells to form L-lysine, a naturally occurring ... The most concerning short-term adverse effects of stimulants, such as elevated blood pressure and heart rate, waned in long- ...

https://en.wikipedia.org/wiki/Lisdexamfetamine

https://en.wikipedia.org/wiki/Adderall

... cerebral blood flow to the cortical area in use must increase proportionally. Along with the increase in flow, hemoglobin ... Hershel Toomim and his wife Marjorie have repeatedly found that NIR HEG training can consciously enhance regional cerebral ... PIR has a poorer resolution than NIR and this treatment typically focuses on more global increases in cerebral blood flow. The ... Neurovascular coupling is the mechanism by which cerebral blood flow is matched to metabolic activity. When a region of the ...

https://en.wikipedia.org/wiki/Hemoencephalography

There were accusations of blood libel by the priests, and new riots against the Jews in Poznań in 1399. Accusations of blood ... The common goals of the Polish state and of the Zionist movement, of increased Jewish population flow to Palestine, resulted in ... covering a wide range of views and vying for votes in local and regional elections. Zionism became very popular with the advent ... Article 31 of the Statute of Kalisz tried to rein in the Catholic Church from disseminating blood libels against the Jews, by ...

https://en.wikipedia.org/wiki/History_of_the_Jews_in_Poland

A Cessna 414 carrying seven people crashes in McLean County, Illinois, two miles east of Central Illinois Regional Airport, ... Roth, Andrew, "Russia cuts gas flow, Ukraine closes airspace as trade war expands," washingtonpost.com, 25 November 2015, 11:25 ... the leader of the Signed In Blood Battalion and former senior member of al Qaeda in the Islamic Maghreb. dropping several 500- ... Mitsubishi Regional Jet 19 December - Epic E1000 - N331FT 25 December - KB SAT SR-10 15 January - Airbus A350 with Qatar ...

https://en.wikipedia.org/wiki/2015_in_aviation

Afterpains (pains similar to menstrual cramps), contractions of the uterus to prevent excessive blood flow, continue for ... GBD 2013 Mortality Causes of Death Collaborators (January 2015). "Global, regional, and national age-sex specific all-cause and ... There is a higher risk of blood clots forming in the legs or pelvis - anti-clot stockings or medication may be ordered to avoid ... Pre-eclampsia is a disorder of pregnancy in which there is high blood pressure and either large amounts of protein in the urine ...

https://en.wikipedia.org/wiki/Childbirth

"Music: High Baptismal Flow: Part 2: The 13th Floor Elevators' ground floors: Where are they now?". The Austin Chronicle. ... In 2009, "You're Gonna Miss Me" was used at length during a scene in episode 21 of Alan Ball's HBO series True Blood, ... ex-lead singer of Zakary Thaks has spoken repeatedly of how the Elevators stood apart from all the other bands on the regional ... 113-. ISBN 978-0-87930-855-1. Moser, Margaret (August 20, 2004). "High Baptismal Flow: Part 2, The 13th Floor Elevators' ground ...

https://en.wikipedia.org/wiki/The_13th_Floor_Elevators

Secular law, like most other aspects of prostitution in the Middle Ages, is difficult to generalize due to the regional ... According to social activists, the steroid can cause diabetes, high blood pressure and is highly addictive. Thailand's Health ... Trotsky, Leon (September 1938). "New War Flows from Versailles Banditry". Marxists.org. Retrieved 14 March 2017. Gerdy, Tom (29 ... Services may be advertised over the Internet, in regional publications, or in local telephone listings. Use of the Internet by ...

https://en.wikipedia.org/wiki/Prostitution

They were the third largest Nez Percé regional group and their tribal area was one of the four centres for the large regional ... as the Clearwater flows into the Snake River here), in Wallowa Mountains and in the Seven Devils Mountains in Oregon and Idaho ... the Kainai or Bloods (Káínaa), and the Siksika or Blackfoot (Siksikáwa), later joined by the unrelated Sarcee (Tsuu T'ina) and ... Their tribal area was one of the four centers for the major regional groups of the Nez Percé. Mákapu Band ("People from Máka/ ...

https://en.wikipedia.org/wiki/Nez_Perce

In this way, they created a large literature in regional languages that embedded Islamic culture deeply into older South Asian ... However, some Indian Muslims were found with detectable, traceable, minor to some levels of gene flow from outside, primarily ... "Every device short of massacre in cold blood was resorted to in order to convert heathen subjects". Hindus who converted to ... Air Chief Marshal Idris Hasan Latif, PVSM Archived 18 May 2011 at the Wayback Machine Civil-military relations: regional ...

https://en.wikipedia.org/wiki/Islam_in_India

He copied his subjects down to the blood. So he drained the Chief's blood and took it into himself. But he wasn't able to ... With the nanomachines gone... Time will unfreeze and begin to flow again. KCEJ. Metal Gear Solid. Roy Campbell: This is Mei ... regional complications, and global terrorist activities; Metal Gear Solid 3 would later retcon the year FOXHOUND was ... He even injects the blood of those he impersonates into his own body for a more "perfect" disguise. Along with the rest of his ...

https://en.wikipedia.org/wiki/List_of_Metal_Gear_characters

Katz, Paul (2005), When the Valleys Turned Blood Red: The Ta-Pa-Ni Incident in Colonial Taiwan, Honolulu, HA: University of ... Under the KMT structure, "Taiwanese" became a strong "regional" identity. The term has often been used synonymously with ... soaring inflation and an increasing flow of immigrants from China (see February 28 Incident)[citation needed]. The latter were ... According to Akatuang, Taiwan's independence shouldn't be established on the idea of blood relations and these people "ignore ...

https://en.wikipedia.org/wiki/Taiwanese_people

His research interests are the regulation of blood pressure and the effect of high blood pressure on the kidneys. He also ... He has been recognized for his use of modern probabilistic methods in the design of networks to monitor rainfall and river flow ... In 1986, he delivered the first child born from the in-vitro fertilization procedure in all of Puerto Rico at the Regional ... a hormone system that helps regulate long-term blood pressure and blood volume in the body and is controlled primarily by the ...

https://en.wikipedia.org/wiki/List_of_Puerto_Rican_scientists_and_inventors

The flow of the aforementioned rivers have been modified in the late 19th century, and while it prevented larger floods and ... The city had a gross metropolitan product of more than $100 billion in 2015, making it one of the largest regional economies in ... Hungary has several wine regions producing among others the worldwide famous white dessert wine Tokaji and the red Bull's Blood ... The Danube also flows through parts of Germany, Austria, Slovakia, Serbia, and Romania. It is navigable within Hungary for 418 ...

https://en.wikipedia.org/wiki/Economy_of_Hungary

Sistemas de dominio regional en el sur de México. El Colegio de Mexico. pp. 165-178. doi:10.2307/j.ctvhn07nx.12. ISBN ... refreshed by a flowing stream, and ending with Mictlāntēcutli, the god of death. The mother with her child is celebrating her ... "Trough Blood & Fire: the Revolutionary Image of Ricardo Flores Magón, Archives , Journal of Undergraduate Research" (PDF). ... The state of Oaxaca has one of many Mexican regional styles of music. At the bottom right of the panel, a compassionate looking ...

https://en.wikipedia.org/wiki/Oaxaca_en_la_historia_y_en_el_mito

They drained blood and caused painful skin sores that became infected, causing lion numbers to crash from 75-100 to 12. The ... Smaller ash eruptions and lava flows continue to slowly fill the current crater. Its name in Maasai means 'Mountain of God'. ... Active Volcanism and Regional Plateaus. Springer. pp. 103-114. ISBN 9783319737843. Estesa, R. D.; Atwood, J. L.; Estes, A. B. ( ... Drought in 1961 and rains throughout the 1962 dry season caused a massive build-up of blood-sucking stable flies (Stomoxys ...

https://en.wikipedia.org/wiki/Ngorongoro_Conservation_Area

As Varlam Shalamov wrote: "Hungry and exhausted, we leaned into a horse collar, raising blood blisters on our chests and ... The largest denominations, the Baptist, Methodist, and Presbyterian churches, split over the slavery issue into regional ... Ebb and Flow of Influences (Leiden, 1995). See also M.O. Koshy, The Dutch Power in Kerala (New Delhi, 1989); K.K. Kusuman, ...

https://en.wikipedia.org/wiki/Slavery

Blood up to your knees': defeated IS jihadists still defiant". Yahoo! News. 8 March 2019. Retrieved 9 March 2019. "SDF: ... with hundreds of civilians and dozens of surrendering militants regularly flowing out of the enclave. The evacuees included ... "very likely will continue to pursue external attacks from Iraq and Syria against regional and Western adversaries, including ... SDF authorities said the freed "have no Syrian blood on their hands," suggesting that they did not take part in any fighting. ...

https://en.wikipedia.org/wiki/Deir_ez-Zor_campaign_(2017–2019)

Men will sometimes mix their blood with a women's menstrual blood, letting them flow together in a ceremonial unification of ... The main regional differences found between the serpent rock art are in the tail of the serpent and the head of the serpent; ... According to legend, the sisters are travelling together when the older sister gives birth, and her blood flows to a waterhole ... Bininj Kunwok Regional Language Centre. Retrieved 16 June 2019. Taylor (1990), p. 330 and 1996. Carroll, Colleen (1 September ...

https://en.wikipedia.org/wiki/Rainbow_Serpent

"Reuters, Move over, blood diamonds". Features.us.reuters.com. Archived from the original on 16 February 2008. Retrieved 16 ... Development of regional airports and expansion of existing airport capacity, and 3) Maintenance and consolidation of urban ... and bizarrely builds itself a new capital city while failing to address the increasingly urgent challenges of refugee flows, ... is noted for its rare pigeon's blood rubies and blue sapphires. Myanmar is famed for its production of Golden South Sea Pearls ...

https://en.wikipedia.org/wiki/Economy_of_Myanmar

In 2011, the Member States engaged in an RCA Regional project to study the disaster impact on the marine environment. The data ... exposure of workers and/or researchers who have been exposed to ionizing radiation through the analyses of blood samples. The ... products through gel permeation chromatography and separates different molecular weight fractions by tangential flow filtration ... "Status of Philippine Regulatory Infrastructure for the Safe Transport of Radioactive Materials." Presented at Regional Training ...

https://en.wikipedia.org/wiki/Philippine_Nuclear_Research_Institute

For example, blood can be said to flow in a proximal or distal direction, and anteroposterior, mediolateral, and inferosuperior ... Regions The more detailed regional approach subdivides the cavity into nine regions, with two vertical and two horizontal lines ... Something that is patent may also refer to a channel such as a blood vessel, section of bowel, collecting system or duct that ... such as blood vessels or leaf veins. Patent, meaning a structure such as an artery or vein that abnormally remains open, such ...

https://en.wikipedia.org/wiki/Anatomical_terminology

Joel Skornicka, 82, American politician, Mayor of Madison, Wisconsin (1979-1983), blood clot. Johnny Wheeler, 91, English ... tributes flow for Champion Hurdle hero Make A Stand Fleet St legend Chris Moncrieff dies aged 88 Morreu Joaquim Moutinho, ... member of the Regional Representative Council (2014-2019), and mayor of Pangkal Pinang (2003-2013). Robert Lyon, 96, British ... ORF regional studios, Kunst- und Ausstellungshalle der Bundesrepublik Deutschland). Maximilian Raub, 93, Austrian sprint canoer ...

https://en.wikipedia.org/wiki/Deaths_in_November_2019

The mass expulsion of the Ugandan Asians in 1972 and that of Goans from Malawi added to the flow. The 1975 independence of ... It was spoken primarily by the Portuguese colonists, Luso-Asians, and elites and middle-class people of pure Chinese blood. As ... In Asia-Pacific regional Conference on Underwater Cultural Heritage Proceedings. Edited by Mark Staniforth, Jennifer Craig, ... Many Luso-Malays possess Chinese blood. Many Luso-Malays emigrated to Penang and Singapore during the period of the Straits ...

https://en.wikipedia.org/wiki/Luso-Asians

... where Fi is blood flow (noted Q in the Figure above), Cart incoming arterial blood concentration, Pi the tissue over blood ... gut loss and regional variation in gut absorption. Each type of modeling technique has its strengths and limitations. PBPK ... Blood flow, assuming that the drug is transported mainly by blood, as is often the case, is then the limiting factor to ... blood) volumetric flow rate through the organ times the incoming blood concentration. In that case; for a generic compartment i ...

https://en.wikipedia.org/wiki/Physiologically_based_pharmacokinetic_modelling

After 2010 due to the economic crisis in Greece there is a new migratory flow of Greeks to New Zealand. A number of Greek New ... Christodoulos, Moisa, Blood and Koka Kola - Short Stories, 2013. Kyriazopoulos, Michael, Cloudy Sunday, 2013. Daglas, Christina ... In Wellington there are a number of associations whose membership is based on regional origin: namely Macedonia, Crete, Ithaca ... Greek organisations representing different regional or national sub-groups have helped sustain the culture. ...

https://en.wikipedia.org/wiki/Greek_New_Zealanders

... and a number of other hemodynamic and blood level factors. Modeling of fluid flows to predict the likelihood of red cell ... Sokol RJ, Hewitt S, Stamps BK (June 1981). "Autoimmune haemolysis: an 18-year study of 865 cases referred to a regional ... machinery is used for intraoperative blood salvage. A centrifuge process takes blood from the patient, washes the red blood ... Hemolysis may result from intrinsic defects in the red blood cell itself: Defects of red blood cell membrane production (as in ...

https://en.wikipedia.org/wiki/Hemolysis

... "full-bloods". "Full-bloods" were then subtracted from the official population figure in accordance with the legal advice from ... One last impact of the referendum has been the benefits of counting all Indigenous Australians flowing from the removal of ... that regional land councils should be established; to establish a fund to purchase land with which Aboriginal people had a ... The benefits of the referendum began to flow to Aboriginal people in 1972. On 26 January 1972, Aboriginal peoples erected the ...

https://en.wikipedia.org/wiki/1967_Australian_referendum_(Aboriginals)

Writing to the Regional Inspector of My Feelings While in Prison I was raised in a secluded place in Boyang, With chaste heart ... Blood splattered my silk garment, but to the end no regrets, Stained my embroidered sleeves, but how could I turn back? The ... My red lips now taste falling tears, alone I bear this wrong, My jade tears flowing criss-cross, I sigh over this injustice. ... Her long narrative poem, Writing to the Regional Inspector of My Feelings While in Prison alludes to her defending herself ...

https://en.wikipedia.org/wiki/Cheng_Changwen

Ultrasound can show the free fluid collection in the right iliac fossa, along with a visible appendix with increased blood flow ... GBD 2013 Mortality Causes of Death Collaborators (January 2015). "Global, regional, and national age-sex specific all-cause and ... This blockage leads to increased pressures in the appendix, decreased blood flow to the tissues of the appendix, and bacterial ... The combination of inflammation, reduced blood flow to the appendix and distention of the appendix causes tissue injury and ...

https://en.wikipedia.org/wiki/Appendicitis

Regional cerebral blood flow (rCBF) was measured in AD patients. 2. Eye-head coordination was analyzed using a Vision analyzer ... Regional cerebral blood flow (rCBF) was measured in AD patients. 2. Eye-head coordination was analyzed using a Vision analyzer ... Regional cerebral blood flow (rCBF) was measured in AD patients. 2. Eye-head coordination was analyzed using a Vision analyzer ... Regional cerebral blood flow (rCBF) was measured in AD patients. 2. Eye-head coordination was analyzed using a Vision analyzer ...

https://tohoku.elsevierpure.com/en/publications/eye-head-coordination-abnormalities-and-regional-cerebral-blood-f

ANS parameters (skin potential and resistance, skin temperature and blood flow, instantaneous heart rate) and instantaneous ... ANS parameters (skin potential and resistance, skin temperature and blood flow, instantaneous heart rate) and instantaneous ...

https://pubmed.ncbi.nlm.nih.gov/1615039/?access_num=1615039&link_type=MED&dopt=Abstract

Arterial spin-labeling parameters influence signal variability and estimated regional relative cerebral blood flow in normal ... Arterial spin-labeling parameters influence signal variability and estimated regional relative cerebral blood flow in normal ...

https://pure.johnshopkins.edu/en/publications/arterial-spin-labeling-parameters-influence-signal-variability-an-3/fingerprints/

Regional cerebral blood flow (rCBF) during migraine using 99m Tc-hexamethylpropyleneamineoxime ( 99m Tc-HMPAO) and single ... Regional cerebral blood flow (rCBF) during migraine using 99m Tc-hexamethylpropyleneamineoxime ( 99m Tc-HMPAO) and single ... Regional cerebral blood flow (rCBF) during migraine using 99m Tc-hexamethylpropyleneamineoxime ( 99m Tc-HMPAO) and single ... Regional cerebral blood flow (rCBF) during migraine using 99m Tc-hexamethylpropyleneamineoxime ( 99m Tc-HMPAO) and single ...

https://research.vumc.nl/en/publications/regional-cerebral-blood-flow-rcbf-during-migraine-using-sup99msup

Leptomeningeal metastases: reduction in regional cerebral blood flow and cognitive impairment. Siegal, T., Mildworf, B., Stein ... Leptomeningeal metastases: reduction in regional cerebral blood flow and cognitive impairment.. Twenty-six patients with ... and measurement of regional cerebral blood flow (rCBF) using the xenon 133 inhalation technique. At diagnosis 50% of the ...

https://www.wikigenes.org/e/ref/e/3985577.html

Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study. Brain. 1997 Jul. 120 ( Pt 7):1173-97. [QxMD ... the blood flow throughout the entire brain progressively decreases. PET studies also show that, during REM sleep, blood flow ... The increase in blood flow to the primary visual regions of the cortex may explain the vivid nature of REM dreaming, while the ... continued decrease in blood flow to the prefrontal cortex may explain the unquestioning acceptance of even the most bizarre ...

https://emedicine.medscape.com/article/1188226-overview

Increased endothelial nitric oxide (NOS-III) expression, increased regional cerebral blood flow, and increased density of ... Cerebral blood flow measurements. Cerebral blood flow (CBF) measurements were performed using the 14C-iodoantipyrine technique ... absolute regional cerebral blood flow in the vicinity of the lateral ventricle wall was also significantly increased in Gsn−/− ... increased regional cerebral blood flow, and increased endothelial nitric oxide synthase (NOS-III) expression in hippocampus. ...

https://www.jneurosci.org/content/30/9/3419.long

Blood Flow Metab. 26, 1122-1127 (2006).. Article PubMed Google Scholar *. Zuo, X. -N. et al. Growing together and growing apart ... High consistency of regional cortical thinning in aging across multiple samples. Cereb. Cortex 19, 2001-2012 (2009). ... Regional variation in interhemispheric coordination of intrinsic hemodynamic fluctuations. J. Neurosci. 28, 13754-13764 (2008). ... As we demonstrated, regional changes in cortical thickness asymmetry are an overlooked yet important feature of normal brain ...

https://www.nature.com/articles/s41467-021-21057-y?error=cookies_not_supported&code=67bd867f-985e-4135-a10d-0b29d3be2a28

SPECT scanning allows for the evaluation of qualitative or semiquantitative regional blood flow. The information provided is ... Intracranial thrombus can appear similar in signal to flowing blood on time-of-flight (TOF) gradient-echo (GRE) MRA. In ... technique involving the inhalation of xenon gas allows for the quantitative determination of regional cerebral blood flow, ... Flow is most easily measured in the middle cerebral arteries, which have been found to have flow velocities normally in the 30- ...

https://emedicine.medscape.com/article/344342-overview

TGN 020 is an aquaporin 4 (AQP4) channel blocker (IC50 = 3.1 μM). Increases regional cerebral blood flow and reduces ischemia- ... Inhibition of aquaporin-4 significantly increases regional cerebral blood flow. Igarashi et al.. Neuroreport, 2013;24:324 ...

https://www.rndsystems.com/products/tgn-020_5425

The regional counts were related to the cerebellar counts and regional cerebral blood flow is expressed as this ratio for each ... The method has been described earlier in detail.26 Regional count densities (regional cerebral blood flow) were calculated for ... 1995) Regional cerebral blood flow measured by 99mTc-HMPAO SPECT differs in subgroups of Alzheimers disease. J Neural Transm ... Regional cerebral blood flow ratios referred to the cerebellum were examined by 99mTc-HMPAO SPECT. Apolipoprotein E genotypes ...

https://jnnp.bmj.com/content/64/6/742

Quantification of myocardial blood flow: Blood flow quantification at rest and stress is used to measure myocardial flow ... Regional flow reserve shows the physiological significance of epicardial CAD, analogous to invasive fractional flow reserve ( ... The ability to routinely quantify myocardial blood flow in ml/min/gram is unique to PET and improves accuracy, risk ... e. Patients in whom myocardial blood flow quantification is identified by clinicians to be a needed adjunct to the image ...

https://jnm.snmjournals.org/content/57/10/1654

At age 44, she suffered a heart attack, and doctors put stents in her arteries to improve blood flow to her heart. ... She works with very ill patients at Magnolia Regional Health Center in Corinth, Mississippi, and it can be stressful at times. ... From there I was admitted to the hospital and sent to the intensive care unit for three days to correct my blood pressure and ... I signed in and went to get my height, weight, and blood pressure checked. The nurse encouraged me to go straight to the ...

https://www.cdc.gov/workplacehealthpromotion/features/hospital-employees-health.html

A Case of Intravascular Lymphoma with Increased Regional Cerebral Blood Flow in I-123 IMP Single-Photon Emission CT Chihoko ... Physiologic Change in Flow Velocity and Direction of Dural Venous Sinuses with Respiration: MR Venography and Flow Analysis ...

https://www.ajnr.org/content/25/4

A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.. ...

https://portal.research.lu.se/en/persons/aki-johanson

Dataset collected during a study on type 2 diabetes on brain blood flow, vasoreactivity and functional outcomes (gait and ... J Cereb Blood Flow Metab 2004; 24:1393-1399.. *Keymeulen B, Jacobs A, de Metx K, de Sadeleer C, Bossuyt A, Somers G. Regional ... We applied continuous arterial spin labeling at 3 Tesla MRI to evaluate regional distribution of cerebral blood flow and ... We applied continuous arterial spin labeling at 3 Tesla MRI to evaluate regional distribution of cerebral blood flow and ...

https://www.physionet.org/content/cerebral-perfusion-diabetes/1.0.1/data/

Influence of muscle strength and body weight and composition on regional bone mineral density in healthy women aged 60 years ... Enhancing strength and postocclusive calf blood flow in older people with training with blood-flow restriction. J Aging Phys ... Low-intensity resistance training with blood flow restriction improves vascular endothelial function and peripheral blood ... Blood flow restriction by low compressive force prevents disuse muscular weakness. J Sci Med Sport 2011;14:95-9.doi:10.1016/j. ...

https://bjsm.bmj.com/content/51/13/1003.long

The Effect of Movement Predictability on Regional Cerebral Blood Flow," Brain, Vol.123, pp. 1216-1228, 2000. ...

https://www.fujipress.jp/jaciii/jc/jacii001700030425/

Similar to heart-bypass procedures, this is where a surgeon takes veins from elsewhere in the body to reroute blood flow around ... UVA is a regional pioneer in subintimal angioplasty. Your surgeon inserts a wire into the wall of the affected artery. Once the ... If you have severe PAD, you may need a procedure to break up blockages or route blood flow around a blockage. ... Doctors use this device to break up blockages in the artery and improve blood flow. ...

https://uvahealth.com/services/aortic-artery-disease/peripheral-artery-disease

The current study assessed the effects of dietary nitrate on cognitive performance and prefrontal cortex cerebral blood-flow ( ... and increase regional perfusion in the brain. ... See Blood Video). Oxy Powder - Natural Colon Cleanser! Cleans ... In neurobiology the HR involves the rapid delivery of blood to active neuronal tissues. The blood vessel dilating effects of ... It has been shown to improve endothelial function, reduce blood pressure and the oxygen cost of sub-maximal exercise, ...

https://beforeitsnews.com/alternative/2017/03/beet-juice-boosts-cognitive-function-in-one-dose-3-3493549.html?replytocom=739318

These blood clots can cause extreme pain in the back, chest, hands and feet. The disrupted blood flow can also cause damage to ... The misshapen cells lack plasticity and can block small blood vessels, impairing blood flow. This condition leads to shortened ... Round red blood cells can move easily through the blood vessels but sickled shaped cells interconnect and can result in blood ... Poor blood oxygen levels and blood vessel blockages in people with sickle-cell disease can lead to chronic acute pain syndromes ...

https://www.afro.who.int/health-topics/sickle-cell-disease

... fractional flow reserve) method is used to calculate the blood pressure differential ... Global Fractional Flow Reserve market analysis Overview The FFR ( ... Regional Analysis. During the forecast period, North America is ... The FFR (fractional flow reserve) method is used to calculate the blood pressure differential through stenosis in coronary ... 3.2 Regional Production Market Analysis. Chapter 4 Global Fractional Flow Reserve Sales, Consumption, Export, Import by Regions ...

https://www.medgadget.com/2021/08/fractional-flow-reserve-market-to-grow-at-high-cagr-industry-size-acne-treatment-trends-in-depth-analysis-top-10-company-profiles-regional-revenue-forecast-to-2027.html

... and postictal changes in regional cerebral blood flow may be useful to differentiate epileptic from non-epileptic episodes (61- ... Li R, Li Y, An D, Gong Q, Zhou D, Chen H. Altered regional activity and inter-regional functional connectivity in psychogenic ... Blood Markers. Several serologic measures have been used to differentiate epilepsy from PNES. One of the most useful markers ... Both studies revealed the presence of decreased regional cortical thickness in PNES patients; however, the study by Labate et ...

https://www.frontiersin.org/articles/10.3389/fneur.2020.00461/full

Luce JM, Ross BK, OQuin RJ, Culver BH, Sivarajan M, Amory DW, Regional blood flow during cardiopulmonary resuscitation in dogs ... including particle removal efficiency and air-flow rate. A Met One Model 227B Hand-Held Particle Counter (Met One, Inc., Grants ...

https://wwwnc.cdc.gov/eid/article/10/2/03-0700

The flow of oxygen-rich blood is blocked from a section of the heart due to plaque buildup in coronary arteries. ... The heart is not pumping blood as it should, and the need for blood and oxygen is not being met.. What are the symptoms?. ... A lifelong disorder of the blood vessels of the heart that can lead to heart attack.. What are the symptoms?. ... Columbus Regional Health pursues Comprehensive Master Plan with City of Columbus for Future Site Development of Westside Farm ...

https://www.crh.org/healthy-tomorrow/healthy-tomorrow/2018/02/23/don-t-miss-a-beat-with-these-heart-facts

Demonstration of dose-dependent global and regional cocaine-induced reductions in brain blood flow using a novel approach to ... Kaufman MJ, Levin JM, Maas LC, et al. Cocaine decrease relative cerebral blood volume in humans: a dynamic susceptibility ... Cocaine produces a dose dependent increase in blood pressure and heart rate, which, in recreational doses, usually remains ... These include increased heart rate and blood pressure and simultaneous coronary vasospasm with reduced oxygen delivery leading ...

https://pmj.bmj.com/content/81/959/568

... they keep the blood flowing and the oxygen flowing to the brain," said Alex Karney of the Susquehanna Regional EMS. ...

https://www.wnep.com/article/news/local/lycoming-county/man-meets-first-responders-who-saved-his-life/523-9f2f7dd1-0c90-4dfa-8095-3eecdd58ced3

Septic shock and specific organ response  Regional circulation Altered blood flow  Microcirculation  Development of ... DEFINITIONS INFECTION- When a pathogen is detected in blood or tissue. Bacteremia-presence of viable bacteria in the blood.  ... Blood glucose correction: target 80 to 150mg/dl.  Red cells, FFP and platelet: keep hemoglobin between 7 to 9 g/dl.  FFP only ... Identifying high risk q sofa:  Respiratory rate at least 22 breaths/minute  Systolic blood pressure 100 mm Hg or lower  ...

https://fr.slideshare.net/AdityaRaghav5/sepsispptx-256865254

Regional cerebral blood flow (rCBF) was measured in AD patients. (elsevierpure.com)
reduction in regional cerebral blood flow and cognitive impairment. (wikigenes.org)
Furthermore, increased hippocampal neurogenesis in Gsn −/− mice was associated with a special microenvironment characterized by enhanced density of perfused vessels, increased regional cerebral blood flow, and increased endothelial nitric oxide synthase (NOS-III) expression in hippocampus. (jneurosci.org)
TGN 020 is an aquaporin 4 (AQP4) channel blocker (IC 50 = 3.1 μ M). Increases regional cerebral blood flow and reduces ischemia-induced brain edema in mice. (rndsystems.com)
Inhibition of aquaporin-4 significantly increases regional cerebral blood flow. (rndsystems.com)
OBJECTIVES In mild Alzheimer's disease, SPECT imaging of regional cerebral blood flow has highlighted deficits in the posterior association cortex, and later in the disease process, the deficit spreads to involve the frontal cortex. (bmj.com)
Regional cerebral blood flow ratios referred to the cerebellum were examined by 99m Tc-HMPAO SPECT. (bmj.com)
A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT. (lu.se)
It comprises cerebral blood, autonomic functions, laboratory and gait variables in 70 patients with type 2 DM and 70 healthy controls (50-85 years old). (physionet.org)
Predictors of cerebrovascular complications of diabetes that are evidence-based on cerebral blood flow, MRI imaging, and cognitive testing are lacking. (physionet.org)
Blood flow velocities were measured in the anterior and middle cerebral arteries using transcranial Doppler ultrasound. (physionet.org)
Cerebral vasoregulation was evaluated by comparing blood flow velocity responses during hypocapnia and hypercapnia, Valsalva maneuver, head-up tilt and sit-to-stand test using simultaneous recordings of cardiovascular variables, blood flow velocity in the anterior and middle cerebral artery using transcranial Doppler and respiratory variables. (physionet.org)
We applied continuous arterial spin labeling at 3 Tesla MRI to evaluate regional distribution of cerebral blood flow and vasomotor reactivity to CO2. (physionet.org)
The current study assessed the effects of dietary nitrate on cognitive performance and prefrontal cortex cerebral blood-flow (CBF) parameters in healthy adults. (beforeitsnews.com)
Overall research focuses on cerebral blood flow and metabolism under normal and conditions and in response to brain injury. (upenn.edu)
Abnormal regional cerebral blood flow in childhood autism. (bvsalud.org)
Flow velocity and pulsatility index were measured in the middle cerebral, basilar and intracranial internal carotid arteries of a sample of 141 diabetic patients with no other risk factors, and 132 age- and sex-matched healthy controls. (who.int)
Cerebral blood flow in diabetes mellitus: evi- tions , 1996, 10:228-242. (who.int)
Effects of different regional cerebral blood flow on white matter hyperintensity in CADASIL patients. (cdc.gov)

Furthermore, the combination of information gained from consistent and high-quality perfusion images, peak stress regional and global contractile function, and quantitation of myocardial blood flow permits identification of very low-risk patients that can obviate the need for further cardiac tests, reduce unnecessary medication expenses, lead to expeditious referrals for assessment of other causes of symptoms, and relieve anxiety over potential life-threatening etiologies for symptoms. (snmjournals.org)
It has been shown to improve endothelial function, reduce blood pressure and the oxygen cost of sub-maximal exercise, and increase regional perfusion in the brain. (beforeitsnews.com)

What I really like about this study is that brain performance can be improved fairly rapidly in healthy people with a simple activity like drinking beetroot juice (high in dietary nitrates, which leads to more nitric oxide to open up oxygen flow in the brain). (beforeitsnews.com)
The blood vessel dilating effects of beet nitrate and subsequent increases in oxygen and nutrients may help explain the improvements in cognitive function in the intervention group. (beforeitsnews.com)
Haemoglobin disorders are inherited blood diseases that affect how oxygen is carried in the body. (who.int)
Poor blood oxygen levels and blood vessel blockages in people with sickle-cell disease can lead to chronic acute pain syndromes, severe bacterial infections, and necrosis (tissue death). (who.int)
The flow of oxygen-rich blood is blocked from a section of the heart due to plaque buildup in coronary arteries. (crh.org)
The heart is not pumping blood as it should, and the need for blood and oxygen is not being met. (crh.org)
In those instances, they keep the blood flowing and the oxygen flowing to the brain," said Alex Karney of the Susquehanna Regional EMS. (wnep.com)

Diabetes mellitus alters the permeability of the blood-brain barrier, thus affecting regional metabolism and microcirculatory regulation. (physionet.org)

Round red blood cells can move easily through the blood vessels but sickled shaped cells interconnect and can result in blood clots. (who.int)
The misshapen cells lack plasticity and can block small blood vessels, impairing blood flow. (who.int)
A lifelong disorder of the blood vessels of the heart that can lead to heart attack. (crh.org)

Thus, local blood flow, metabolism, and reaction, by lowering the Dose response is the most fundamental concept of toxicology. (cdc.gov)

Arterial stiffness was measured using carotid-femoral pulse wave velocity, the speed of blood flow from the upper to the lower aorta. (medscape.com)

At age 44, she suffered a heart attack, and doctors put stents in her arteries to improve blood flow to her heart. (cdc.gov)
The FFR (fractional flow reserve) method is used to calculate the blood pressure differential through stenosis in coronary arteries (blockage). (medgadget.com)
Stiffer arteries disrupt blood flow to the liver and pancreas, which could adversely affect their functioning, he said. (medscape.com)

Your doctor may also prescribe medication to help reduce cholesterol and blood-pressure levels and to help prevent blood clots. (uvahealth.com)
These blood clots can cause extreme pain in the back, chest, hands and feet. (who.int)

If you have severe PAD, you may need a procedure to break up blockages or route blood flow around a blockage. (uvahealth.com)
Similar to heart-bypass procedures, this is where a surgeon takes veins from elsewhere in the body to reroute blood flow around a blockage in the artery. (uvahealth.com)
The wire has a transducer on the tip that monitors blood pressure, temperature, and flow in order to assess the magnitude of the blockage. (medgadget.com)

1, 2 Cocaine may be taken by smoking, nasal inhalation, or injection with varying pharmacokinetics leading to peak blood concentration ranging from 1 to 90 minutes. (bmj.com)
Respiratory which inhalation dosimetric relationships contribute to this tract uptake of halothane, acetone, ethanol and diacetyl was species difference in regional airway injury is not known, but measured in male F344 rat to obtain data for model validation. (cdc.gov)

Doctors use this device to break up blockages in the artery and improve blood flow. (uvahealth.com)
The aim of this study is to assess reduction in CVD risk susceptibility among regular blood donors compared with nondonors using ultrasound brachial artery flow-mediated dilation (BAFMD). (bvsalud.org)

15 It has been suggested that mildly affected patients show temporoparietal and some frontal changes, whereas more severely demented patients also show decreased blood flow in other regions-for example, the occipital areas. (bmj.com)
She works with very ill patients at Magnolia Regional Health Center in Corinth, Mississippi, and it can be stressful at times. (cdc.gov)
This dataset was collected as part of a study to explore vasoregulation and blood flow in patients with type 2 Diabetes mellitus. (physionet.org)
La vitesse d'écoulement du flux sanguin et l'index de pulsatilité ont été mesurés dans les artères carotides internes intercrâniennes, les artères basilaires et cérébrales moyennes d'un échantillon de 141 patients diabétiques sans autre facteur de risque et de 132 témoins en bonne santé appariés pour l'âge et le sexe. (who.int)
Les patients ont été répartis en deux groupes : 73 patients souffrant d'un diabète compliqué dans le premier groupe et 68 patients atteints d'un diabète non compliqué dans le deuxième groupe. (who.int)
A prospective comparative study designed to establish the difference between mean flow-mediated dilatation (FMD) in the patients who are regular blood donors compared with nondonors recruited from a Teaching Hospital donor clinic. (bvsalud.org)

There was no reopening after the ductal closure during the hospital stay or in the follow-up visits in either group and no excessive increases in the blood urea nitrogen or serum creatinine levels were observed. (who.int)

Free acidity, total acidity, basal acid output, serum pepsinogen I, gastric mucosal blood flow [‏GMBF]‏ and gastrin were significantly lower in group II, whereas serum gastrin and somatostatin staining were significantly higher. (who.int)
BAFMD was significantly greater in regular blood donors when compared with nondonors (13.95% ± 7.02% vs. 8.20% ± 4.19%, P = 0.000). (bvsalud.org)
Serum ferritin was significantly decreased in regular blood donors when compared with nondonors (mean value 41.92 ng/ml ± 23.12 ng/ml vs. 61.97 ± 30.19 ng/ml, P = 0.000), but Hb did not differ between the groups. (bvsalud.org)

The Disease Management Program, sponsored by the hospital's main Wellness Program, pays for her blood pressure and diabetes medicines. (cdc.gov)

ANS parameters (skin potential and resistance, skin temperature and blood flow, instantaneous heart rate) and instantaneous respiratory frequency are quantified by original techniques and indices. (nih.gov)

Stents are inserted to open a blocked passageway to improve blood flow. (uvahealth.com)

Background and objective Low-load exercise training with blood flow restriction (BFR) can increase muscle strength and may offer an effective clinical musculoskeletal (MSK) rehabilitation tool. (bmj.com)

DEFINITIONS INFECTION- When a pathogen is detected in blood or tissue. (slideshare.net)

Damage to these organs may increase insulin and LDL cholesterol blood levels, increasing the risk for metabolic syndrome. (medscape.com)

In the Region, the majority of children with the most severe form of the disease die before the age of 5, usually from an infection or severe blood loss. (who.int)

I signed in and went to get my height, weight, and blood pressure checked. (cdc.gov)
The nurse encouraged me to go straight to the emergency room because my blood pressure was very elevated. (cdc.gov)
From there I was admitted to the hospital and sent to the intensive care unit for three days to correct my blood pressure and sugar levels. (cdc.gov)
Now Fitz has lost 25 pounds, brought his blood pressure and sugar levels under control, and been able to cut down on his medicine intake. (cdc.gov)
The pressure after a stenosis compared to the pressure before the stenosis is known as fractional flow reserve. (medgadget.com)
Track your weight, blood pressure and fluids daily. (crh.org)
Physicians should refer at-risk teens to a preventative clinic where they can be monitored and receive repeated measurements of arterial stiffness, lipid levels, blood pressure, glucose levels, and obesity every 3 months, Agbaje said. (medscape.com)
Arterial stiffness also can lead to higher blood pressure and insulin resistance , potentially inducing musculogenesis and vasculogenesis. (medscape.com)

The disrupted blood flow can also cause damage to bones, muscles and organs. (who.int)

Natural Medicines Comprehensive Database (La Base Exhaustiva de Datos de Medicamentos Naturales) clasifica la eficacia, basada en evidencia científica, de acuerdo a la siguiente escala: Eficaz, Probablemente Eficaz, Posiblemente Eficaz, Posiblemente Ineficaz, Probablemente Ineficaz, Ineficaz, e Insuficiente Evidencia para Hacer una Determinación. (medlineplus.gov)

This condition leads to shortened red blood cell survival, and subsequent anaemia, often called sickle-cell anaemia. (who.int)

In sickle cell disease, the normal round shape of red blood cells become like crescent moons. (who.int)

HELLIS is coordinated by WHO Regional Office for South-East Asia. (who.int)

Sickle-cell disease is characterized by a modification in the shape of the red blood cell from a smooth, donut-shape into a crescent or half moon shape. (who.int)

The flow of BLOOD through or around an organ or region of the body. (bvsalud.org)

During the forecast period, these trends are expected to propel the global fractional flow reserve market forward. (medgadget.com)
During the forecast period, North America is predicted to maintain its dominance in the global fractional flow reserve market. (medgadget.com)
As a result, the launch of current, as well as new treatment solutions across North America and Europe, is projected to drive growth in the global fractional flow reserve market over the forecast period. (medgadget.com)

100 eligible regular male blood donors , aged 21-50 years, were selected from a Teaching Hospital blood donor records and their BAFMD assessed. (bvsalud.org)

Anatomy23

Organisms8

Diseases7

Chemicals and Drugs23

Analytical, Diagnostic and Therapeutic Techniques and Equipment28

Phenomena and Processes31

Disciplines and Occupations1

Named Groups1

Intrarenal site of action of calcium on renin secretion in dogs. (1/9283)

Vascular remodeling in response to altered blood flow is mediated by fibroblast growth factor-2. (2/9283)

Role of endothelin in the increased vascular tone of patients with essential hypertension. (3/9283)

Bronchial artery perfusion scintigraphy to assess bronchial artery blood flow after lung transplantation. (4/9283)

Pulsed Doppler ultrasonographic evaluation of portal blood flow in dogs with experimental portal vein branch ligation. (5/9283)

Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. (6/9283)

Sonographic evidence for the involvement of the utero-ovarian counter-current system in the ovarian control of directed uterine sperm transport. (7/9283)

Endothelial function in Marfan syndrome: selective impairment of flow-mediated vasodilation. (8/9283)

Regional Blood Flow

Microspheres

Blood Flow Velocity

Cardiac Output

Cerebrovascular Circulation

Hemodynamics

Blood Circulation

Vascular Resistance

Dogs

Coronary Circulation

Splanchnic Circulation

Blood Pressure

Scandium

Renal Circulation

Liver Circulation

Pulmonary Circulation

Laser-Doppler Flowmetry

Xenon Radioisotopes

Heart Rate

Anesthesia

Oxygen

Blood Gas Analysis

Radioisotopes

Nafronyl

Oxygen Consumption

Nitrogen Radioisotopes

Tomography, Emission-Computed

Phentolamine

Ventilation-Perfusion Ratio

Oxygen Radioisotopes

Kidney

Brain

Swine

Hindlimb

Carbon Dioxide

Microcirculation

Organotechnetium Compounds

Immersion

Vasoconstriction

Partial Pressure

Models, Cardiovascular

Iliac Artery

Blood Volume

Renal Artery

Ischemia

Vasodilation

Pulmonary Gas Exchange

Vasodilator Agents

Supine Position

Anesthesia, Inhalation

Time Factors

NG-Nitroarginine Methyl Ester

Heart

Collateral Circulation

Myocardium

Isoflurane

Leg

Infusions, Parenteral

Nitric Oxide

Mesenteric Arteries

Cats

Flow Cytometry

Rats, Sprague-Dawley

Propranolol

Tomography, Emission-Computed, Single-Photon

Forearm

Sympathetic Nervous System

Muscle, Skeletal

Sheep

Norepinephrine

Rats, Wistar

Rats, Inbred Strains

Injections, Intravenous

Nitric Oxide Synthase

Pulsatile Flow

Rabbits

Dose-Response Relationship, Drug

Coronary Vessels

Disease Models, Animal

Magnetic Resonance Imaging