Rare Diseases: A large group of diseases which are characterized by a low prevalence in the population. They frequently are associated with problems in diagnosis and treatment.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Hinduism: A complex body of social, cultural, and religious beliefs and practices evolved in and largely confined to the Indian subcontinent and marked by a caste system, an outlook tending to view all forms and theories as aspects of one eternal being and truth, and the practice of the way of works, the way of knowledge, or the way of devotion as a means of release from the round of rebirths. (From Webster, 3d ed)Sanitation: The development and establishment of environmental conditions favorable to the health of the public.IndiaBuddhism: The teaching ascribed to Gautama Buddha (ca. 483 B.C.) holding that suffering is inherent in life and that one can escape it into nirvana by mental and moral self-purification. (Webster, 3d ed)Islam: A monotheistic religion promulgated by the Prophet Mohammed with Allah as the deity.Red Cross: International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.ABO Blood-Group System: The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.Blood Grouping and Crossmatching: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.Blood DonorsBlood Group Antigens: Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties.Yukon Territory: A territory of northwest Canada, bounded on the north by the Arctic Ocean, on the south by British Columbia, and on the west by Alaska. Its capital is Whitehorse. It takes its name from the Yukon River, the Indian yu-kun-ah, meaning big river. (From Webster's New Geographical Dictionary, 1988, p1367 & Room, Brewer's Dictionary of Names, 1992, p608)Positive-Pressure Respiration: A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.Cell Line, Tumor: A cell line derived from cultured tumor cells.Molecular Targeted Therapy: Treatments with drugs which interact with or block synthesis of specific cellular components characteristic of the individual's disease in order to stop or interrupt the specific biochemical dysfunction involved in progression of the disease.Soft Tissue Injuries: Injuries of tissue other than bone. The concept is usually general and does not customarily refer to internal organs or viscera. It is meaningful with reference to regions or organs where soft tissue (muscle, fat, skin) should be differentiated from bones or bone tissue, as "soft tissue injuries of the hand".Blood Banks: Centers for collecting, characterizing and storing human blood.Hospitals, County: Hospitals controlled by the county government.Science: The study of natural phenomena by observation, measurement, and experimentation.Soft Tissue Infections: Infections of non-skeletal tissue, i.e., exclusive of bone, ligaments, cartilage, and fibrous tissue. The concept is usually referred to as skin and soft tissue infections and usually subcutaneous and muscle tissue are involved. The predisposing factors in anaerobic infections are trauma, ischemia, and surgery. The organisms often derive from the fecal or oral flora, particularly in wounds associated with intestinal surgery, decubitus ulcer, and human bites. (From Cecil Textbook of Medicine, 19th ed, p1688)Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Heart: The hollow, muscular organ that maintains the circulation of the blood.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Myositis: Inflammation of a muscle or muscle tissue.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Bulimia: Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as "ox hunger".Miller Fisher Syndrome: A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Eccrine Glands: Simple sweat glands that secrete sweat directly onto the SKIN.Bartholin's Glands: Mucus-secreting glands situated on the posterior and lateral aspect of the vestibule of the vagina.Nipples: The conic organs which usually give outlet to milk from the mammary glands.Vulvar Diseases: Pathological processes of the VULVA.Maxillary Sinus: The air space located in the body of the MAXILLARY BONE near each cheek. Each maxillary sinus communicates with the middle passage (meatus) of the NASAL CAVITY on the same side.Breast: In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.Carcinoma, Adenoid Cystic: Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)Mucolipidoses: A group of inherited metabolic diseases characterized by the accumulation of excessive amounts of acid mucopolysaccharides, sphingolipids, and/or glycolipids in visceral and mesenchymal cells. Abnormal amounts of sphingolipids or glycolipids are present in neural tissue. INTELLECTUAL DISABILITY and skeletal changes, most notably dysostosis multiplex, occur frequently. (From Joynt, Clinical Neurology, 1992, Ch56, pp36-7)Mucopolysaccharidosis I: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase (IDURONIDASE) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity from severe to mild: Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome (formerly mucopolysaccharidosis V). Symptoms may include DWARFISM; hepatosplenomegaly; thick, coarse facial features with low nasal bridge; corneal clouding; cardiac complications; and noisy breathing.Mucopolysaccharidosis VII: Mucopolysaccharidosis characterized by excessive dermatan and heparan sulfates in the urine and Hurler-like features. It is caused by a deficiency of beta-glucuronidase.Mucopolysaccharidosis VI: Mucopolysaccharidosis with excessive CHONDROITIN SULFATE B in urine, characterized by dwarfism and deafness. It is caused by a deficiency of N-ACETYLGALACTOSAMINE-4-SULFATASE (arylsulfatase B).Fucosidosis: An autosomal recessive lysosomal storage disease caused by a deficiency of ALPHA-L-FUCOSIDASE activity resulting in an accumulation of fucose containing SPHINGOLIPIDS; GLYCOPROTEINS, and mucopolysaccharides (GLYCOSAMINOGLYCANS) in lysosomes. The infantile form (type I) features psychomotor deterioration, MUSCLE SPASTICITY, coarse facial features, growth retardation, skeletal abnormalities, visceromegaly, SEIZURES, recurrent infections, and MACROGLOSSIA, with death occurring in the first decade of life. Juvenile fucosidosis (type II) is the more common variant and features a slowly progressive decline in neurologic function and angiokeratoma corporis diffusum. Type II survival may be through the fourth decade of life. (From Menkes, Textbook of Child Neurology, 5th ed, p87; Am J Med Genet 1991 Jan;38(1):111-31)Mucopolysaccharidosis II: Systemic lysosomal storage disease marked by progressive physical deterioration and caused by a deficiency of L-sulfoiduronate sulfatase. This disease differs from MUCOPOLYSACCHARIDOSIS I by slower progression, lack of corneal clouding, and X-linked rather than autosomal recessive inheritance. The mild form produces near-normal intelligence and life span. The severe form usually causes death by age 15.Iduronidase: An enzyme that hydrolyzes iduronosidic linkages in desulfated dermatan. Deficiency of this enzyme produces Hurler's syndrome. EC 3.2.1.76.Pediatrics: A medical specialty concerned with maintaining health and providing medical care to children from birth to adolescence.Sentinel Surveillance: Monitoring of rate of occurrence of specific conditions to assess the stability or change in health levels of a population. It is also the study of disease rates in a specific cohort such as in a geographic area or population subgroup to estimate trends in a larger population. (From Last, Dictionary of Epidemiology, 2d ed)Communicable DiseasesBiopharmaceutics: The study of the physical and chemical properties of a drug and its dosage form as related to the onset, duration, and intensity of its action.Virus Diseases: A general term for diseases produced by viruses.United States Food and Drug Administration: An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.Drug Approval: Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.
mertensiana; rare. Leaves greener, less glaucous above, paler below; cones indistinguishable from the type. At one time it was ...
E. Y. Watson The type locality is Darjeeling. Rare. Watson also gave this detailed description: Male and female brown. ...
The type locality is Nilgiris in South India. Not rare. The Indian awlking is 50 to 60 mm long. It is distinguished by the ...
The type locality is New Caledonia. Very rare. The larva has been recorded on Callerya megasperma and Wisteria sinensis. ...
B - Battery (rare). *Third letter (job type): *G - Goods. *P - Passenger. *M - Mixed (goods and passenger) ...
A rare type. This type is represented by the coins of five cities in present-day Shanxi, between the Fen and Yellow River. ... Another rare type. Two sizes are found. The large size has the inscription liang (Chinese: 兩; pinyin: liǎng) on the reverse; ... The type is contemporary, along with the pointed foot spades. Some mints issued both types, and the two are found together in ... for other types the copper content varies between 40% and 70%. Arched foot spades: this type has an arched crutch like an ...
A rare type, this type is represented by the coins of five cities in present-day Shanxi, between the Fen and Yellow River. ... Another rare type. Two sizes are found. The large size has the inscription liang (Chinese: 兩; pinyin: liǎng) on the reverse; ... The type is no doubt contemporary with the pointed foot spades; some mints issued both types, and the two are found together in ... It could be that this type was merely a local variation of the Pointed Tip knives, or that it was the original type that became ...
Meat type. Cooking variation. PhIP ng/g ± SD Beef (1.5 cm thick). Fried - medium rare (51 °C). 0.29 ± 0.14 ... Doneness levels of meat (rare, medium, well-done, and very well-done) are factors in the development of PhIP. Methods to reduce ... Exposure is also related to the type of meat, doneness, cooking method, and quantity consumed. Individual exposures can differ ...
catfish (rare, usually written 鯰). Types of kanji by category[edit]. Main article: Chinese character classification ... In OS X, typing 「じおくり」will reveal the symbol 々 as well as ヽ、ゝ and ゞ. To produce 〻, type 「おどりじ」. Under Windows, typing「くりかえし」 ... Generally, on'yomi are classified into four types according to their region and time of origin:. *Go-on (呉音, "Wu sound") ... However, they occasionally have a Chinese on reading, derived from a phonetic, as in 働, dō, from 動, and in rare cases only have ...
Rare." Froese, Rainer, and Daniel Pauly, eds. (2012). Species of Bidenichthys in FishBase. June 2012 version. Nielsen, JG; ... Common." Bidenichthys capensis Barnard, 1934 (Freetail brotula): The type species for the genus; "intertidal in rocky tidepools ...
This is an extremely rare type of small cell, and there has been little information in the scientific community. It appears to ... Ismaili N (November 2011). "A rare bladder cancer - small cell carcinoma: review and update". Orphanet Journal of Rare Diseases ... In the prostate, small-cell carcinoma (SCCP) is a rare form of cancer (approx 1% of PC). Due to the fact that there is little ... 15% of lung cancers in the US are of this type. Small cell lung cancer occurs almost exclusively in smokers; most commonly in ...
Rainfall is rare. However, during the severe floods that struck Venezuela in December 1999 ("Vargas tragedy", being especially ... composed of three types of dunes; and a littoral plain with a belt of mangrove swamps. The massive sand dunes, known as Médanos ...
The type locality is northeast Bengal. It is considered rare. Calliana pieridoides as per LepIndex. Card for Calliana ...
There are 6 types of Armours and Weapons: •Common Class (Cheap,Weak) •Rare Class (Cheap,Weak) •Epic Class (Cheap,Not very ...
The type locality is the Khasi Hills. It is very rare. Card for Capila pennicillatum in LepIndex. Accessed 04 November 2007. ...
... is a type of food poisoning from eating marine turtles. It is considered rare. Hawksbill turtle meat is one ...
Other very rare types of primary headaches include: cluster headaches: short episodes (15-180 minutes) of severe pain, usually ... The most common types of primary headaches are migraines and tension-type headaches. They have different characteristics. ... Triptans are not helpful in tension-type headaches unless the person also has migraines. For chronic tension type headaches, ... The type of preventive medicine is usually chosen based on the other symptoms the person has. For example, if the person also ...
The cups of this type date to about 550 BC. The earliest specimens are completely black, a type that remains in production ... Figural decoration is rare. Details of the post-540 decorative style are so similar to cups from Laconia that a connection must ... The type goes mostly out of use around 510 BC, although black-slipped cups continue to be made for longer. John Percival Droop ... Droop cups (pronounced: Drope) are a type of Little-master cup in the pottery of ancient Greece, produced about 550 to 510 BC, ...
The "tudati" type is named after the Sanskrit verb that typifies this formation. It is much rarer than the normal type. ... There were also two types: normal type: *(é)-eti ~ *(é)-onti. Accented e-grade root. "tudati" type: *(∅)-éti ~ *(∅)-ónti. Zero- ... This formation was maybe even rarer than the root thematic type, only one verb is reconstructable. Examples: *wéwket. *(ḗ)-s-t ... Affixes of various types were used to switch the inherent aspect to a different type. Such affixes created "characterised" verb ...
... (CDA) is a rare blood disorder, similar to the thalassemias. CDA is one of many types of ... CDA Type I, CDA Type II, CDA Type III, and CDA Type IV . CDA type II (CDA II) is the most frequent type of congenital ... "Congenital dyserythropoietic anemia type 2 , Disease , Treatment , Genetic and Rare Diseases Information Center (GARD) - an ... Congenital dyserythropoietic anemia type IV- is defined by having severe anemia at birth (type V and VI are recognized). ...
Rare) Teruzuki (War at Sea Starter; Destroyer; Common) Tone (War at Sea; Cruiser; Rare) Type 13 Subchaser (War at Sea; Escort; ... Rare) Provence (Condition Zebra; Battleship; Rare) Richelieu (War at Sea; Battleship; Rare) Suffren (Flank Speed; Cruiser; Rare ... Rare) USS Intrepid (CV-11) (Flank Speed; Aircraft Carrier; Rare) USS Iowa (BB-61) (War at Sea; Battleship; Rare) USS John C. ... Rare) USS Washington (BB-56) (War at Sea; Battleship; Rare) USS Wasp (CV-7) (Surface Action; Aircraft Carrier; Rare) USS West ...
Other types are rare. Play media Three quarters of affected patients are asymptomatic. However, 25% develop cyanosis, ... Type I has a large (>2 cm) multiloculated cysts. Type II has smaller uniform cysts. Type III is not grossly cystic, referred to ... In this situation, a special surgical type of delivery called the EXIT procedure may be used. In rare extreme cases, where ... CPAM type 1 is the most common, with large cysts and a good prognosis. CPAM type 2 (with medium-sized cysts) often has a poor ...
... s are rare diseases. About 1 in 5,000 babies are born with some type of skeletal dysplasia. Achondroplasia ... Deformity type Erlenmeyer flask gives a distal femur similar to an Erlenmeyer flask. It may result from Gaucher disease. Kashin ... Langer-Giedion syndrome is a very rare genetic disorder caused by a deletion of chromosomal material. Diagnosis is usually made ... Osteogenesis imperfecta is a rare condition in which bones break easily. There are multiple genetic mutations in different ...
Rare types[edit]. *Diabetes mellitus and deafness, a mitochondrial disease associated with the gene "Leu-UUR" ... Types of diabetes mellitus[edit]. Common types[edit]. *Diabetes mellitus type 1, a form of diabetes mellitus that results from ... Diabetes mellitus type 2, a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance ... to help persons with Type 1 and Type 2 diabetes manage their disease ...
Moroha: A rare, double-edged tantō type that has a diamond-shaped cross-section. The blade tapers to a point and contains a ... Kissaki-moroha: A rare blade type with a double-edged point. Unlike the later kanmuri-otoshi the tip had a distinct shape ... Kubikiri: A very rare type; the sharpened blade is on the inside curve rather than the outside. It has no sharpened point, ... Shinogi: This is the most common type of blade geometry for long swords, but tantō made in this form are very rare, usually ...
It is a type of neurogenic pain. *Patients with the prontaor teres syndrome have numbness in median nerve distribution with ... Rare causes such as following tendon transfers for radial palsy. *Dissimilarity to CTS: *Positive Tinel's sign in forearm ...
... a type that accounts for fewer than 5% of pancreatic cancers and, experts say, differs substantially from the more common kind ... Steve Jobss Pancreatic Cancer Was Rare Type. Steve Jobs had what is called a neuroendocrine pancreatic tumor, a type that ... go ... experts say the slow progress of the rare form of pancreatic cancer that afflicted Apple CEO Steve Jobs was typical but ... Spying High: A Rare Trip in Americas U-2 Spy Plane. 6/7/2018 10:42AM ...
Neurofibromatosis Type 1. In: NORD Guide to Rare Disorders. Lippincott Williams & Wilkins. Philadelphia, PA. 2003:563-64. ... NORDs Rare Disease Database provides brief introductions for patients and their families to more than 1,200 rare diseases. ... RareConnect offers a safe patient-hosted online community for patients and caregivers affected by this rare disease. For more ... NF1 is a rare disorder that affects males and females in equal numbers. NF1 affects all races and ethnic groups equally and is ...
Optical glasses containing the oxides of rare earths such as lanthanum to impart a very high refractive index combined w... ... rare-earth type glass. Optical glasses containing the oxides of rare earths such as lanthanum to impart a very high refractive ...
Pericardial mesothelioma is an extremely rare type of cancer that originates in the lining of the heart and is caused by ... Mesothelioma › Types › Pericardial Mesothelioma Pericardial Mesothelioma. Pericardial mesothelioma is an extremely rare form of ... A rare case of primary malignant pericardial mesothelioma. Journal of Clinical Imaging Science. August 2014;4:47. doi: 10.4103/ ... It is one of the rarest forms of mesothelioma, accounting for 1 - 2% of all diagnoses. Prognosis is extremely poor, with most ...
"We were most surprised that the virus infects such a rare cell type and that even with so few cells infected, the infections ... Norovirus Cruises to Rare Cell Type in GI Tract. April 13, 2018. 0 ... a rare chemosensory type of epithelial cell The findings highlight tuft cells as a potential target for the development of ... Recent studies have found that tuft cells produce interleukin-25 (IL-25) and trigger type 2 immune reactions in response to ...
Hi, I have Dercums Disease as well, but mine is type II I think it is. The type where you have diffuse mutated Dercums fat ... I am not an expert on this rare condition. But like you, I am here trying to help. I read about the article of Drs Brorson and ... Ive never had much of a problem with lipomas; up until that point, I was dealing with the type of Dercums Disease where its ... I have a extremily rare orphan disease called Dercums Disease. Is there any doctor on this site familiar with this disease or ...
... than type II muscle fibers. Now, CFTD is usually only when type I fibres are at least 35-40% smaller than type II fibres, on ... and type II fibers are larger than normal (hypertrophic) and often a class of type II fibers (called type IIB fibers) is absent ... Congenital fiber type disproportion (CFTD) is a rare genetic muscle disease that is usually apparent at birth (congenital ... Home / For Patients and Families / Rare Disease Information / Congenital Fiber Type Disproportion ...
... 06.07.2016. Researchers from the University of Zurich and University ... Shortly afterwards, researchers dis-covered that IFAP syndrome, a group of rare dermatological diseases in humans, is caused by ... their teams and colleagues from the USA and Thailand have now detected a new type of brit-tle-bone disease, identifying two ... Childrens Hospital Zurich have dis-covered the first X-chromosome-inherited type of the congenital disease osteogenesis ...
The Food and Drug Administration has approved a new medicine for use against a rare, rapidly progressing blood cancer after ... FDA OKs Pfizer drug for rare, fast-killing type of leukemia. By LINDA A. JOHNSON. Published August 17, 2017. MarketsAssociated ... The Food and Drug Administration has approved a new medicine for use against a rare, rapidly progressing blood cancer after ... The agency approved Pfizer Inc.'s Besponsa for patients with a type of advanced acute lymphoblastic leukemia. By then, ...
A common dietary supplement may help treat a very rare form of autism with epilepsy that is linked to an amino acid deficiency ... Rare find A common dietary supplement may help treat a very rare form of autism with epilepsy that is linked to an amino acid ... Use these social-bookmarking links to share Amino acids may help rare type of autism. ... Amino acids may help rare type of autism. Friday, 7 September 2012 AFP ...
... to treat adults with a rare type of acute lymphoblastic leukemia. ... FDA Panel Backs Drug for Rare Type of Leukemia. by Emily P. ... Adult ALL is one of the rarest types of cancer -- there are about 2,000 new cases of adult ALL diagnosed each year in the U.S ... to treat adults with a rare type of acute lymphoblastic leukemia.. The FDAs Oncologic Drugs Advisory Committee voted 7-4, with ...
... An immunotherapy has become the first of its kind approved to treat Merkel cell ... Thats largely because its so rare - only 1,600 to 2,000 cases occur each year in the U.S. - but the cancer also "looks ... "On the surface, it seems like its a rare cancer, but Merkel cell might provide insight into other cancers," Russell says. "If ... It might seem that such a rare cancer is unlikely to generate enough research to find more answers, but studying MCCs ...
... linking rare DNA alterations to type 2 diabetes. The study, one of the largest known of its type, includes data from people of ... From this large cohort the researchers identified four genes with rare variants that affect diabetes risk. The data suggests ... linking rare DNA alterations to type 2 diabetes. The study, one of the largest known of its type, includes data from people of ... Massive sequencing study links rare DNA alterations to type 2 diabetes Scientists identify new genetic targets for disease ...
However, there is a rare form of diarrhoea, which is caused due to specific genetic mutation in patients. The symptoms of the ...
O positive is the most common type, followed by A... ... AB negative is the least common blood type in the United States ... How Many Blood Types Are There?. A: Humans have four different blood types: A, B, AB and O. Each of these blood types is also ... What Are the Four Different Blood Types?. A: The four different blood types are A, B, AB and O. People with the A blood type ... Why Is AB Negative Blood so Rare?. A: People with AB negative blood type account for 1 percent of the population, according to ...
Learn more about the different types of blood, including which one is the rarest and the role of genetics in determining your ... Whats the rarest blood type?. Its hard to say which blood type is the rarest in the world, since theyre linked to genetics. ... so a person with this type of blood can receive either type A or type B blood. Everyone can receive type O blood because it ... However, because blood type is linked to genetics, there is no single type thats considered to be the rarest worldwide. ...
Platelet-type von Willebrand disease: a rare, often misdiagnosed and underdiagnosed bleeding disorder.. Othman M1. ... Platelet-type von Willebrand disease (PT-VWD) is an autosomal dominant rare bleeding disorder characterized by hyperresponsive ... likely to be misdiagnosed as type 2B VWD or idiopathic thrombocytopenic purpura, and represents 15% of type 2B VWD diagnoses. ... However, the gold standard is to identify mutations within the VWF gene (indicating type 2B VWD) or the platelet GP1BA gene ( ...
UT Southwestern Medical Center researchers have discovered a new therapeutic target for incurable, rare type of soft-tissue ... Potential Therapeutic Target for Incurable, Rare Type of Soft-tissue Cancer Identified. ... including the dominant NF1 type and rarer NF2 and Schwannomatosis forms. Source: Eurekalert ... Middle ear infection, or otitis media, is a common type of infection that may or may not accompany the infections of nose and ...
... your blood type is present in less than one in every 1,000 people. Patients who need rare blood rely on rare blood donors. Give ...
Fragile site, folic acid type, rare, fra(2)(q13) is a protein that in humans is encoded by the FRA2B gene. "Human PubMed ... Reference:". "Entrez Gene: Fragile site, folic acid type, rare, fra(2)(q13)". Retrieved 2017-04-04. ...
... rare type of soft-tissue cancer may be completely eradicated simply by inhibiting a key protein involved in its growth, UT ... Lu Le, left, and graduate student Amish Patel published a study that found by inhibiting a key protein, a rare, incurable type ... 26, 2013 - A deadly, rare type of soft-tissue cancer may be completely eradicated simply by inhibiting a key protein involved ... UTSW study identifies potential therapeutic target for incurable, rare type of soft-tissue cancer. UT Southwestern Medical ...
FDA approves treatment for two rare types of non-Hodgkin lymphoma PR Newswire SILVER SPRING, Md., Aug. 8, 2018 SILVER SPRING, ... FDA approves treatment for two rare types of non-Hodgkin lymphoma. PRNewswire {{following ? "Following" : "Follow"}} ... Mycosis fungoides and Sézary syndrome are rare, hard-to-treat types of non-Hodgkin lymphoma and this approval fills an unmet ... FDA approves treatment for two rare types of non-Hodgkin lymphoma. PR Newswire ...
Outbreak of a rare phage type (DT124) of Salmonella typhimurium in Finland ... Outbreak of a rare phage type (DT124) of Salmonella typhimurium in Finland. Euro Surveill. 1997;1(15):pii=1065. https://doi.org ...
... a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle ... Rare Type of Immune Cell Responsible for Progression of Heart Inflammation to Heart Failure in Mice. ... Different types of myocarditis are distinguished based on the type of immune cell that predominates the inflammation of the ... This type of scar tissue is also found in DCMi. Although both groups of mice had similar degrees of scar tissue, the eosinophil ...
... -- ... to treat three rare types of Periodic Fever Syndromes, also known as Hereditary Periodic Fevers1. This means Novartis will work ... Of the three rare conditions for which Ilaris is being reviewed by the FDA, FMF is the most common and mainly affects people of ... Ilaris was approved by the FDA in 2009 to treat two subtypes of a rare autoinflammatory disease called Cryopyrin-Associated ...
  • Uterine sarcomas, which form in the muscle wall of the uterus, are rare, making up less than 4 percent of all cancers of the uterus. (cancercenter.com)
  • There is a considerable unmet need in this rare, hard-to-treat family of disease, so these results represent a very important milestone in the treatment of soft tissue sarcomas," comments Professor Patrick Schöffski, Head of the Department of General Medical Oncology, University Hospital Leuven, Belgium. (perssupport.nl)
  • Other sarcomas of the kidney are rare but can occur at any age. (cancer.ca)
  • Each of these types is identified as positive or negative, depending on whether the third antigen, the RH factor, is present in the blood. (reference.com)
  • The four different blood types are A, B, AB and O. People with the A blood type have the A antigen in their red blood cells and the B antibody in their pla. (reference.com)
  • When it comes to blood type, you might inherit an A antigen from one parent and a B antigen from the other, resulting in the AB blood type. (healthline.com)
  • This means that if you inherit an O from your mother and an A from your father, for example, your blood type would be A. It's also possible that two people with type A or type B blood could have a baby with type O blood if they carry the O antigen. (healthline.com)
  • Depending on whether the Rh antigen is present, each blood type is assigned a positive or negative symbol. (healthline.com)
  • For example, AB blood has both the A and B antigen, so a person with this type of blood can receive either type A or type B blood. (healthline.com)
  • Patch points to a patient in Fort Hamilton, Ohio, who needs regular transfusions, and another woman in Eastern Ohio who needs blood with a rare antigen only found in people of Amish descent. (wvxu.org)
  • The child's red blood cells don't have an antigen called Indian B. So the donor should have O or A blood type with the same missing antigen. (mmaringreport.com)
  • Zainab Mughal, 2, is missing a common Indian-B antigen, meaning she'll need a rare donor who is also missing that antigen. (mmaringreport.com)
  • The patient, who the organization has only identified as "Zainab," has an aggressive childhood cancer called neuroblastoma, and an extremely rare blood type, where she's missing an antigen called Indian B or Inb. (orlandoweekly.com)
  • Brachydactyly - long thumb syndrome is a very rare autosomal dominant heart-hand syndrome (see this term) that is characterized by bisymmetric brachydactyly accompanied by long thumbs, joint anomalies (restriction of motion at the shoulder and metacarpophalangeal joints) and cardiac conduction defects. (nih.gov)
  • Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a very rare and lethal tumor, mostly affecting young women, with aggressive clinical course. (thefreelibrary.com)
  • Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is exceedingly rare tumor with very aggressive behavior and strikingly poor prognosis. (thefreelibrary.com)
  • As one example cell hybrids, formed as result of fusion between cancer cells and cells of the tumor microenvironment, are rare and are significantly influenced by the local microenvironment. (jcancer.org)
  • Basal cell adenoma (BCA) of the salivary glands is a rare benign tumor resembling pleomorphic adenoma, but with a prominent basaloid cell layer. (scopemed.org)
  • The agency approved Pfizer Inc.'s Besponsa for patients with a type of advanced acute lymphoblastic leukemia. (foxbusiness.com)
  • It also carries an increased risk of death in patients who have received a certain type of stem cell transplant. (foxbusiness.com)
  • Roughly a quarter of autism patients have epileptic seizures, but Gleeson said this particular condition is believed to be "extremely rare. (abc.net.au)
  • However, there is a rare form of diarrhoea, which is caused due to specific genetic mutation in patients. (thehindubusinessline.com)
  • Mycosis fungoides and Sézary syndrome are rare, hard-to-treat types of non-Hodgkin lymphoma and this approval fills an unmet medical need for these patients,' said Richard Pazdur , M.D., director of the FDA's Oncology Center of Excellence and acting director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research. (benzinga.com)
  • We are committed to continuing to expedite the development and review of this type of targeted therapy that offers meaningful treatments for patients. (benzinga.com)
  • The approval was based on a clinical trial of 372 patients with relapsed MF or SS who received either Poteligeo or a type of chemotherapy called vorinostat. (benzinga.com)
  • In 2013, the FDA approved Ilaris for a rare, autoinflammatory form of juvenile idiopathic arthritis called Systemic Juvenile Idiopathic Arthritis (SJIA) in patients aged two and older. (prnewswire.com)
  • 2 This Rare Pediatric Designation, a first for AbbVie, is an important advancement as we continue to evaluate ABT-414 and its potential to help this group of patients who desperately need a new treatment option," said Gary Gordon, M.D., vice president, oncology clinical development, AbbVie. (drugs.com)
  • Two patients experienced acute renal failure but underwent a full recovery following treatment for MM. We conclude from our analysis that treatment approaches for severe type I CG should involve plasmapheresis at the onset to achieve a rapid control of the CG-related symptoms and that specific MM treatments should be introduced also at an early stage to avoid CG relapse. (biomedsearch.com)
  • On July 3, the U.S. Food and Drug Administration (FDA) approved Beleodaq (belinostat) for the treatment of patients with peripheral T-cell lymphoma, a rare and fast-growing type of non-Hodgkin lymphoma. (americannursetoday.com)
  • Mark Roschewski, M.D., of the Lymphoid Malignancies Branch is leading a study to determine if pembrolizumab can improve outcomes for patients with certain rare lymphomas such as large B cell lymphoma, shown here. (cancer.gov)
  • A newly opened clinical trial led by Mark Roschewski, M.D., of the Lymphoid Malignancies Branch is seeking to determine if pembrolizumab can improve outcomes for patients with certain rare lymphomas. (cancer.gov)
  • Although 60% of patients with IMN develop cold type antibodies, clinically significant hemolytic anemia with a high ferritin level is very rare and validity of serum ferritin as an important biomarker has not been used frequently. (biomedcentral.com)
  • Connect with other caregivers and patients with Acromesomelic dysplasia Hunter Thompson type and get the support you need. (rareguru.com)
  • Herein, a Accepted 11 September 2017 smart yolk-shell type nanocomposites based on the covalent encapsulation of a Yb(III) complex in Available online 11 September 2017 magnetism mesoporous silica nanoparticles (NPs) has been designed and assembled for IDDS. (deepdyve.com)
  • EAST HANOVER, N.J. , April 27, 2016 /PRNewswire/ -- Novartis today announced that the US Food and Drug Administration (FDA) has granted three Breakthrough Therapy Designations for Ilaris ® (canakinumab) to treat three rare types of Periodic Fever Syndromes, also known as Hereditary Periodic Fevers 1 . (prnewswire.com)
  • Hereditary spastic paraplegias are divided into two types: pure and complex. (medlineplus.gov)
  • Like all hereditary spastic paraplegias, spastic paraplegia type 7 involves spasticity of the leg muscles and some muscle weakness. (medlineplus.gov)
  • Studies in mice by researchers at Washington University School of Medicine (WUSM) have now thrown new light on norovirus infection, and shown that the virus specifically infects intestinal tuft cells, a rare chemosensory type of epithelial cell The findings highlight tuft cells as a potential target for the development of therapeutics or vaccines that could help to treat or prevent norovirus infection. (genengnews.com)
  • And while the researchers had determined that "rare isolated intestinal epithelial cells" could be infected by norovirus during chronic infection, expression of CD300lf on epithelial cells hadn't previously been reported. (genengnews.com)
  • For their latest studies, the WUSM researchers used immunofluorescence to identify a scant population of CD300lf-expressing cells in the ilea and colons of mice, the shape of which suggested that the cells were tuft cells, a cell type found in hollow organs. (genengnews.com)
  • Together, our immunofluorescence and flow cytometric analyses indicate that tuft cells are the physiologic target cell of MNoV in WT [wild-type] animals," the researchers write. (genengnews.com)
  • Researchers in PR China have now succeeded in synthesizing a new type of intermetallic nanocapsule that can be applied in cyrogenic magnetic refrigerator devices. (nanowerk.com)
  • Such a new type of nanoparticle, in the form of a superparamagnetic GdAl 2 nanocapsule, was synthesized by the Chinese researchers. (nanowerk.com)
  • This type of model allows researchers to study effects specific to the loss of the protein. (medicalxpress.com)
  • Rare find A common dietary supplement may help treat a very rare form of autism with epilepsy that is linked to an amino acid deficiency, a new study has found. (abc.net.au)
  • O positive is the most common type, followed by A positive as the second most common, and then B positive. (reference.com)
  • The fourth most common blood type among the U.S. population is AB positive, notes the American Red Cross. (reference.com)
  • In India, for example, the most common blood type is B-positive, while in Denmark it's A-positive. (healthline.com)
  • Of the three rare conditions for which Ilaris is being reviewed by the FDA, FMF is the most common and mainly affects people of Eastern Mediterranean ancestry, affecting 1 in 250 to 1 in 1,000 individuals in these populations. (prnewswire.com)
  • Geneticists have made the somewhat artificial distinction between 'common' and 'rare' when describing alleles at polymorphic genetic loci. (biomedcentral.com)
  • It is a common fact that it is extremely difficult to synthesize the nanoparticles/nanocapsules with rare-earth elements or compounds because of the chemical activity of the rare earths. (nanowerk.com)
  • In addition to these physical characteristics, individuals with SED Maroteaux type have some common radiographic findings, including platyspondyly (flattened vertebral bodies in the spine), abnormalities of the pelvis and severe brachydactyly (short fingers and toes). (nih.gov)
  • This is quite a rare occurrence in humans but is quite common in animals and usually results in a twin or higher-order multiple pregnancies where the fetuses show an obvious difference in gestational development. (twinsmagazine.com)
  • Hi, They are more common than what they were 20 years ago,but i agree still pretty rare i ended up traveling 90 miles to get mine,and when i got there was not in great condition but between traveling to get her i took her anyway. (caudata.org)
  • Wilms tumour is the most common type of cancerous kidney tumour in children. (cancer.ca)
  • Also referred to as benign multicystic mesothelioma, benign cystic mesothelioma, and BMPM, this type of peritoneal mesothelioma is most common in women of reproductive age, with only 20 reported cases in men. (mesothelioma.com)
  • This type of mesothelioma is most common in the peritoneum, with rare instances in the pericardium, pleura and tunica vaginalis. (mesothelioma.com)
  • A type of twinning identified as identical on the mother's side but sharing only half their father's genes, these rare twins develop when two sperm fertilize a single egg, forming a triploid, which then split. (twinsmagazine.com)
  • GISTs may mostly represent sporadic cases, but they could also be part of familiar syndromes, such as the Carney triad, Carney--Stratakis syndrome, and neurofibromatosis type 1 (2). (thefreelibrary.com)
  • Investigations revealed that she had cold type autoimmune hemolysis, significantly elevated serum ferritin, elevated serum lactate dehydrogenase level with serological evidence of recent Epstein Barr infection. (biomedcentral.com)
  • Cold type autoimmune hemolytic anemia is a rare manifestation of infectious mononucleosis and serum ferritin is used very rarely as an important biomarker. (biomedcentral.com)
  • hence we describe a case of clinically significant cold type autoimmune hemolytic anemia associate with significantly high serum ferritin as a rare manifestation of IMN. (biomedcentral.com)
  • If a person has been identified as a rare donor and they're called on to give, my hope is that they will donate, if they are able. (kdvr.com)
  • At Community Blood Center, Reference Lab Supervisor Gavin Patch says requests from the rare donor program still arrive by fax machine. (wvxu.org)
  • The symptoms of CFTD are similar to other types of congenital myopathy and may vary from case to case. (rarediseases.org)
  • This abnormal protein appears to have a new, atypical function that interferes with the proliferation or differentiation of chondrocytes, impairing ossification and leading to the signs and symptoms of atelosteogenesis type 1. (medlineplus.gov)
  • Nonfunctional m-AAA proteases cause a build up of unusable proteins in the mitochondria of nerve cells, which can result in swelling of the cell, reduced cell signaling, and impaired cell movement, leading to the major signs and symptoms of spastic paraplegia type 7. (medlineplus.gov)
  • The program, a collaboration between the American Red Cross and AABB , formerly known as the American Association of Blood Banks, is working with OneBlood to secure more rare blood for Zainab. (kdvr.com)
  • MUST be blood type "O" or "A" - All donations for Zainab must be coordinated with OneBlood in advance to ensure the additional compatibility testing is performed. (orlandoweekly.com)
  • Cold type AIHA is mainly caused by lymphoid malignancies and rarely it can be caused by infections mainly Mycoplasma pneumoniae and infectious mononucleosis (IMN). (biomedcentral.com)
  • Although such landraces may not be rare in their home environment, they are considered rare when brought to other parts of the world for pets or (rarely) to do the work for which they originally developed. (wikipedia.org)
  • Optical glasses containing the oxides of rare earths such as lanthanum to impart a very high refractive index combined with a low dispersive power. (photonics.com)
  • As the principal contributor of the novel properties, various magnetic cores of nanocapsules, including rare earths and their carbides, have been researched extensively over the past two decades. (nanowerk.com)
  • The case was essentially reported because of its rare occurrence (pancytopenia and poly-lymphadenopathy which are very rare systemic signs or even exceptional), and because it emphasizes the need for further studies in order to understand how defects in lipid metabolism in NPC can lead to hematological defects especially pancytopenia. (ommegaonline.org)
  • Since the total cases are less than 40,000 a year that makes it a rare occurrence. (blogspot.com)
  • When blood from more than threats, harassment or privacy invasion, impersonation or misrepresentation, fraud or patient, that patient has a rare blood types would be lucky to find blood which. (gethao1p.tk)
  • WASHINGTON -- An FDA advisory committee has tepidly endorsed vincristine sulfate liposomal injection (Marqibo) to treat adults with a rare type of acute lymphoblastic leukemia. (medpagetoday.com)
  • What Are the Different Types of Eye Charts? (reference.com)
  • How Many Different Types of Dammit Dolls Are Available? (reference.com)
  • To decrease the risk of methane explosion, different types of methane sensors based on gas chromatography, semiconductor, infrared and optical interference etc. are developed to monitor and forewarn of the methane concentration [ 1 , 2 ]. (mdpi.com)
  • The parts of the molecule that are mutated are shown in green, blue and red indicating different types of atoms. (edu.au)
  • There are different types of mesothelioma depending on the type of mesothelium affected. (blogspot.com)
  • Spondyloepiphyseal dysplasia (SED) Maroteaux type is a rare skeletal dysplasia that is characterized by short stature beginning in infancy, short, stubby hands and feet, and genu valgum (knock knees). (nih.gov)
  • Intelligence is generally normal and there is no clouding of the cornea, which distinguishes SED Maroteaux type from other forms of spondyloepiphyseal dysplasia. (nih.gov)
  • As seen in acromesomelic dysplasia, Grebe type and acromesomelic dysplasia, Maroteaux type, facial features and intelligence are normal. (rareguru.com)