Gastric Acidity Determination: Gastric analysis for determination of free acid or total acid.Ranitidine: A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.Gastric Acid: Hydrochloric acid present in GASTRIC JUICE.Histamine H2 Antagonists: Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.Anti-Ulcer Agents: Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.Achlorhydria: A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.2-Pyridinylmethylsulfinylbenzimidazoles: Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.Gastric Juice: The liquid secretion of the stomach mucosa consisting of hydrochloric acid (GASTRIC ACID); PEPSINOGENS; INTRINSIC FACTOR; GASTRIN; MUCUS; and the bicarbonate ion (BICARBONATES). (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p651)Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Rabeprazole: A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.Duodenal Ulcer: A PEPTIC ULCER located in the DUODENUM.Gastrins: A family of gastrointestinal peptide hormones that excite the secretion of GASTRIC JUICE. They may also occur in the central nervous system where they are presumed to be neurotransmitters.Bismuth: A metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.Sulfoxides: Organic compounds that have the general formula R-SO-R. They are obtained by oxidation of mercaptans (analogous to the ketones). (From Hackh's Chemical Dictionary, 4th ed)Antacids: Substances that counteract or neutralize acidity of the GASTROINTESTINAL TRACT.Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.Stomach: An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.Gastric Mucosa: Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones.Simethicone: A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base.Benzimidazoles: Compounds with a BENZENE fused to IMIDAZOLES.Proton Pump Inhibitors: Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.Cross-Over Studies: Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)Furans: Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.Magnesium Hydroxide: An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.Helicobacter pylori: A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).Sucralfate: A basic aluminum complex of sulfated sucrose.Postprandial Period: The time frame after a meal or FOOD INTAKE.Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).Esophagus: The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.Heartburn: Substernal pain or burning sensation, usually associated with regurgitation of gastric juice into the esophagus.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Circadian Rhythm: The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs and stimuli, hormone secretion, sleeping, and feeding.Acids: Chemical compounds which yield hydrogen ions or protons when dissolved in water, whose hydrogen can be replaced by metals or basic radicals, or which react with bases to form salts and water (neutralization). An extension of the term includes substances dissolved in media other than water. (Grant & Hackh's Chemical Dictionary, 5th ed)Aluminum Hydroxide: A compound with many biomedical applications: as a gastric antacid, an antiperspirant, in dentifrices, as an emulsifier, as an adjuvant in bacterins and vaccines, in water purification, etc.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Enprostil: A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on gastrin. It has been shown to be efficient and safe in the treatment of gastroduodenal ulcers.Nizatidine: A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.Receptors, Histamine H2: A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)Esophagitis, Peptic: INFLAMMATION of the ESOPHAGUS that is caused by the reflux of GASTRIC JUICE with contents of the STOMACH and DUODENUM.Clarithromycin: A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.Quantitative Structure-Activity Relationship: A quantitative prediction of the biological, ecotoxicological or pharmaceutical activity of a molecule. It is based upon structure and activity information gathered from a series of similar compounds.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.Health Facility Merger: The combining of administrative and organizational resources of two or more health care facilities.Enterochromaffin-like Cells: Neuroendocrine cells in the glands of the GASTRIC MUCOSA. They produce HISTAMINE and peptides such as CHROMOGRANINS. ECL cells respond to GASTRIN by releasing histamine which acts as a paracrine stimulator of the release of HYDROCHLORIC ACID from the GASTRIC PARIETAL CELLS.Enterochromaffin Cells: A subtype of enteroendocrine cells found in the gastrointestinal MUCOSA, particularly in the glands of PYLORIC ANTRUM; DUODENUM; and ILEUM. These cells secrete mainly SEROTONIN and some neuropeptides. Their secretory granules stain readily with silver (argentaffin stain).Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)Body Surface Area: The two dimensional measure of the outer layer of the body.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.
"Determination of the time of onset of action of ranitidine and famotidine on intra-gastric acidity". Aliment. Pharmacol. Ther. ... With gastric malignancies, relief of symptoms due to the use of ranitidine does not exclude the presence of a gastric ... ranitidine was found to be more effective than proton pump inhibitors in reducing the volume of gastric secretions. Ranitidine ... Ranitidine is a competitive, reversible inhibitor of the action of histamine at the histamine H2 receptors found in gastric ...
"Determination of the time of onset of action of ranitidine and famotidine on intra-gastric acidity". Aliment. Pharmacol. Ther. ... With gastric malignancies, relief of symptoms due to the use of ranitidine does not exclude the presence of a gastric ... Ranitidine is a competitive, reversible inhibitor of the action of histamine at the histamine H2 receptors found in gastric ... Short-term and maintenance therapy of gastric and duodenal ulcers. *Ranitidine can also be given with NSAIDs to reduce the risk ...
"Determination of the time of onset of action of ranitidine and famotidine on intra-gastric acidity". Aliment. Pharmacol. Ther. ... With gastric malignancies, relief of symptoms due to the use of ranitidine does not exclude the presence of a gastric ... Ranitidine is a competitive, reversible inhibitor of the action of histamine at the histamine H2 receptors found in gastric ... Short-term and maintenance therapy of gastric and duodenal ulcers. *Ranitidine can also be given with NSAIDs to reduce the risk ...
... on gastric volume and pH in three homogeneous groups undergoing emergency surgery. Group I (10 patients) received placebo, ... cimetidine and ranitidine, given 1 h prior to anesthesia, ... Gastric Acidity Determination. Humans. Male. Middle Aged. ... This paper has studied the effect of i.v. cimetidine and ranitidine, given 1 h prior to anesthesia, on gastric volume and pH in ... There were no significant differences in gastric volume among the three groups. However, treated patients had significantly ...
RESULTS: Pylorus ligation showed a significant (P , 0.01) reduction in gastric volume, free acidity, total acidity and ulcer ... The antiulcer effect of sodium cromoglycate 40 mg/kg b.w., i.p., was compared with the reference drug ranitidine 27 mg/kg b.w ... total acidity, pH, mucin, pepsin and volume of gastric juice were determined. ... i.p. The ulcer index was calculated and other biochemical parameters like free acidity, ...
... along the greater curvature and the gastric juice was collected into a small beaker for volume and acidity determinations (3). ... Figure 1 - Gastric emptying of saline in rats treated with scorpion toxin alone (TX, N = 8), or in combination with ranitidine ... Effect of scorpion toxin on gastric emptying Data concerning gastric emptying are presented in Figure 1. The fraction of the ... Also, the lack of effect of ranitidine rules out an influence of gastric acid hypersecretion, which might theoretically cause ...
Gastro protective potential can be measured by the determination of pH, Gastric content, free and total acidity. The results of ... kg were evaluated by pylorus ligation using Ranitidine (50mg/kg) as standards. The standard drugs and the test drugs were ... Gastric and duodenal ulcers are common pathologies that may be induced by a variety of factors such as stress, smoking and ... Peptic ulcers occur in that part of the gastrointestinal tract which is exposed to gastric acid and pepsin, i.e., the stomach ...
... on experimentally induced gastric ulceration in Wistar rats, SS Sakat, Preeti Tupe, Archana Juvekar ... Determination of total acidity. An aliquot of 1 ml gastric juice diluted with 1 ml of distilled water was taken into a 50 ml ... Ranitidine was used as a standard drug (100 mg/kg). Acid secretory parameters like gastric volume, pH, total acidity and free ... Table 2: effect of meoc on gastric content, ph, total acidity and free acidity in pylorus ligation induced gastric ulceration ...
2.7.3. Determination of Free Acidity and Total Acidity [17, 18]. 1 mL of gastric juice was pipette out into a 100 mL conical ... in group II animals, when compared to control group I. Administration of EEMT and ranitidine showed a significant (. 𝑃. ,. 0. . ... 2.7.2. Determination of pH of Gastric Content [16]. 1 mL of the gastric juice was collected, and pH was directly measured by ... 2.7.1. Determination of Gastric Volume [15]. After sacrificing the rat, the stomach portion was removed. The gastric contents ...
... , Abdulrahman A. I. AL-Yahya, ... The gastric juice accumulated in the stomach was centrifuged and the total acidity [14], mucin [15], pepsin content [16] and ... Except for determination of ulcerogenic potential, the animals were grouped as follows. The first group of animals received ... pylorus ligation induced gastric, ethanol induced gastric, stress induced gastric, and indomethacin induced gastric ulcers. Gum ...
Except for pH and total acidity, MMMC also significantly (P < 0.001) reduced the volume of gastric content but increased the ... activities of the gastric tissue intoxicated by ethanol. UHPLC analysis of MMMC confirmed the presence several flavonoid-based ... and then subjected to the ethanol-induced gastric ulcer or pyloric ligation assays. Stomach of rats from the former assay was ... and enzymatic and non-enzymatic antioxidant studies while the gastric juice content and tissue from the latter assay were ...
... evaluation of gastric content parameters such as volume, pH, free and total acidity, protein estimation, and quantification of ... In pylorus-ligation model, EAF significantly (p <0.001) prevent gastric lesion formation. Volume of gastric content and total ... protein content reduced significantly (p < 0.01 and p < 0.05, respectively), while free and total acidity reduced in the doses ... The mechanism of gastroptotection of EAF was further investigated using pylorus ligation-induced gastric lesion rat model (100 ...
Humans , Male , Female , Erythromycin/pharmacology , Ranitidine/pharmacology , Metoclopramide/pharmacology , Gastric Acidity ... oral erythromycin-ranitidine combination and metoclopramide-ranitidine combination in reducing gastric fluid volume and acidity ... Combination of erythromycin-ranitidine is more effective than metoclopramide-ranitidine in reducing the gastric aspirate fluid ... combination and metoclopramide-ranitidine combination in reducing residual gastric fluid volume and acidity in elective surgery ...
Ranitidine/pharmacology , Carbachol , Gastric Acidity Determination , Rats, Sprague-Dawley ... Evaluation of combined effect of verapamil and ranitidine on the volume and acidity of carbachol induced gastric secretion ... Comparison of effects of verapamil and ranitidine on volume and acidity of carbachol induced gastric secretion ... Animals, Laboratory , Gastric Juice/drug effects , Ranitidine/pharmacology , Rats, Sprague-Dawley , Gastric Juice/metabolism , ...
Gastric acidity was expressed in m Eq/l. - Determination of gastric wall mucus content ... Ranitidine reduced the total acid output by 34.83%. In conclusion, prevention of gastric lesions in rats by VCO was found to ... The gastric juice induced by each different types of oil showed significantly lower total acidity, high in mucus content (µg/g ... Gastric secretion is also blocked by histamine H2-receptor blockers (Schultz, 1979). In the group of rats received Ranitidine ...
... and medications which alter gastric acid levels. Seventy-five patients in a long-term care hospital in Guelph, Ontario were ... Twenty-four-hour intragastric acidity and plasma gastrin concentration before and during treatment with either ranitidine or ... Termanini B, Gibril F, Sutliff VE, Yu F, Venzon DJ, Jensen RT: Effect of long-term gastric acid suppressive therapy on serum ... Assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current ...
1) Pepsin activity 2)free acidity 3)total acidity 4) ulcer index 5)gastric mucus secretion 6) Volume of gastric juice. ... Group IV- Ranitidine(150mg/kg orally for 7days)and Aspirin(400mg/kg orally on the 7th day). ... portion of the stomach and that of ulcerated mucosa were measured for determination of the ulcer index. ... free acidity(5)total acidity (6)gastric mucus secretion were studied. The ulcer index, pepsin activity, free and total acidity ...
... the gastric juice was titrated against 0. 01N sodium hydroxide using Topfers reagent as indicator to find out the free acidity ... o ranitidine(sigma chemicals,Bangalore,India) as standard, Group 3 received 200 mg/kg, p. o ethanolic bark extract of IAF,Group ... This prompted us to pursue the activity and was examined for their efficacy and for determination of their possible mechanism ... Gastric ulceration is a cause of economic loss and a source of welfare concern worldwide. There are 350,000 to 500,000 new ...
Decreased gastric acidity due to any means including proton pump inhibitors, increases gastric counts of bacteria normally ... The "max" value represents determinations at a time of maximum effect (2 to 6 hours after dosing), while "min" values are those ... controlled study of omeprazole 40 mg twice daily for 12 months followed by 20 mg twice daily for 12 months or ranitidine 300 mg ... Serum chromogranin A (CgA) levels increase secondary to drug-induced decreases in gastric acidity. The increased CgA level may ...
... determination of gastric pH.13 The Gastro-Test® compares well with gastric intubation in pH determination and in the diagnosis ... One question that was posed concerning IHNs role in changing gastric acidity was whether or not the decrease in gastric pH ... Studies with omeprazole and ranitidine in intact and antrectomized rats. Gastroenterology 1986;90:391-399.. 6. Carney JA, Go ... gastric acidity reverted to normal. His gastric acid, as measured by the Gastro-Test®, remained normal even after he had fasted ...
Decreased gastric acidity due to any means including proton pump inhibitors, increases gastric counts of bacteria normally ... Treatment of Gastric Ulcer % of Patients Healed (All Patients Treated) 1. (p , 0.01) omeprazole 40 mg versus ranitidine.. 2. (p ... The "max" value represents determinations at a time of maximum effect (2 to 6 hours after dosing), while "min" values are those ... Serum chromogranin A (CgA) levels increase secondary to drug-induced decreases in gastric acidity. The increased CgA level may ...
Ranitidine (Zantac, Zantac 75, Zantac EFFERdose, Zantac injection, and Zantac Syrup). Ranitidine could provide better pain aid ... Acidity is often triggered by an offensive food or as a part of a medical condition by which certain foods not tolerated by the ... Gastric acid also has the additional good thing about serving to to kill off any harmful micro organism or organisms which you ... it is crucial you perceive what is happening in your body so you can also make the absolute best determination in treating acid ...
Ipproton is used as a treatment of other conditions such as the management of gastric or duodenal ulcers, gastroesophageal ... Total 24-hour gastric acid secretion in patients with duodenal ulcer. Here we explore the response of the shell structure of ... Determination of consistent patterns of range of motion in the ankle joint with a computed tomography stress-test. This study ... omeprazole ranitidine gerd dose. *what is omeprazole cap 20mg used for. *omeprazole different brands of water ...
One embodiment includes use of gastric irritating bio-affecting agents in which case the composition is preventative as well as ... Method for the determination of substrates or enzyme activities. US4178393 *. 2 May 1977. 11 Dec 1979. Aktieselskabet ... One embodiment includes use of gastric irritating bio-affecting agents in which case the composition is preventative as well as ... Antacids are any alkaline substance which can be taken internally to neutralize stomach acidity. Substances which can be used ...
Serum chromogranin A (CgA) levels increase secondary to drug-induced decreases in gastric acidity. The increased CgA level may ... and ranitidine 150 mg twice a day were evaluated. Treatment of Gastric Ulcer % of Patients Healed (All Patients Treated) ... The "max" value represents determinations at a time of maximum effect (2 to 6 hours after dosing), while "min" values are those ... Effects on Gastrointestinal Microbial Ecology Decreased gastric acidity due to any means including proton pump inhibitors, ...
The agency also asked ranitidine manufacturers to run their own lab tests on product to assess. Valisure tested ranitidine ... Part I: Determination of the amount of base in antacid tablets Digestion of food occurs in the mouth, stomach and small ... Hydrochloric acid (HCl) is one of the substances found in gastric juices secreted by the lining of the stomach. HCl is needed ... Antacids neutralize stomach acidity to relieve heartburn, sour stomach, acid. simethicone chewable tablet, magaldrate and ...
Attenuation of stress-induced gastric lesions by lansoprazolePD and ranitidine in rats. This validated method is sensitive and ... using the natural logarithmic transformation of the percent decrease from baseline in integrated gastric acidity for the hour ... The method digifalis fully validated for the determination of S-isomers of each drug in their dosage form. ... Attenuation of stress-induced gastric lesions by lansoprazolePD and ranitidine in rats. ...
  • Atrophic gastritis (also known as type A or type B gastritis) is a process of chronic inflammation of the gastric mucosa of the stomach, leading to a loss of gastric glandular cells and their eventual replacement by intestinal and fibrous tissues. (patcue.com)
  • Bile acids can damage the gastric mucosa through various mechanisms. (patcue.com)
  • To elucidate whether human primary gastric cancer and gastric mucosa epithelial cells in vitro can grow normally in a methionine (Met) depleted environment, i.e. (termsreign.cf)
  • The results of the present study showed that the chloroform extract of Phoenix dactylifera leaves possessed gastro protective activity as evidenced by its significant inhibition of mean ulcer score and ulcer index and a marked decrease in gastric content, free and total acidity levels and increase in pH in a dose dependant manner. (wjpr.net)
  • The drug is used in conditions, where the inhibition of gastric acid secretion may be beneficial, including aspiration syndromes, dyspepsia, gastro-oesophageal reflux disease, peptic ulcer disease, and the Zollinger-Ellison syndrome. (faintpower.cf)
  • Peptic ulcers occur in that part of the gastrointestinal tract which is exposed to gastric acid and pepsin, i.e., the stomach and duodenum. (wjpr.net)
  • An imbalance between the aggressive factors such as acid and pepsin secretion, H. pylori, refluxed bile, deliverance of leukotrienes and reactive oxygen species (ROS) and mucosal protective factors that include bicarbonate secretion, mucus-bicarbonate barrier, surface active phospholipids, prostaglandins (PGs), mucosal blood circulation, cell renewal and relocation, non-enzymatic and enzymatic antioxidants and some growth factors [ 4 ] leads to gastric damages. (biomedcentral.com)
  • Pathologic gastrointestinal (GI) hypersecretory conditions such as Zollinger-Ellison syndrome Gastroesophageal reflux disease (GERD) Erosive esophagitis Part of a multidrug regimen for Helicobacter pylori eradication to reduce the risk of duodenal ulcer recurrence Recurrent postoperative ulcer Upper GI bleeding Prevention of acid-aspiration pneumonitis during surgery: ranitidine can be administered preoperatively to reduce the risk of aspiration pneumonia. (wikipedia.org)
  • BACKGROUND AND AIM: The aim of this study was to identify factors affecting persistent gastric regenerating atypia and determine the effect of Helicobacter pylori eradication on the course of this lesion. (bvsalud.org)
  • doses of 15, 150 or 300 mg/kg) and then subjected to the ethanol-induced gastric ulcer or pyloric ligation assays. (biomedcentral.com)
  • The current study was undertaken to evaluate the antiJournal of Pharmacy Research ulcer activity IAF ethanolic extract by aspirin induced gastric ulcer, till now no pharmacological evaluation has been done on IAF especially in leaf for its anti-ulcer activity. (nmmra.org)
  • A multiple-unit floating drug delivery system based on gas formation technique was developed, in order to prolong the gastric residence time and to increase the overall bioavailability of the dosage form. (jyoungpharm.in)
  • Patients with duodenal ulcers do tend to have higher-than-normal levels of hydrochloric acid, but most patients with gastric ulcers have normal or lower-than-normal acid levels. (adam.com)
  • In this retrospective analysis, BMI and LN ratio were independently associated with survival in patients with gastric cancer. (storysteel.cf)
  • Prevention of acid-aspiration pneumonitis during surgery: ranitidine can be administered preoperatively to reduce the risk of aspiration pneumonia. (wikipedia.org)
  • Single-dose pharmacokinetic properties of esomeprazole van children aged 1 - 11 years with endoscopically proven GERD: An analysis of variance model was used to test the pharmacodynamic equivalence of CDFR and omeprazole -DR, using the natural logarithmic transformation of the percent decrease from baseline in integrated gastric acidity for the hour interval after the seventh dose of each omeprazole formulation. (podsolnuhi54.ru)
  • 2D and 3D dose distribution determination in proton beam radiotherapy with GafChromic film detectors. (finasteride2020.site)
  • Data analysis of our study showed statistically significant reduction in mean gastric fluid aspirate volume in group A [3.4ml+2.3 vs. 7.2m1+3. (bvsalud.org)
  • MMMC also improved the catalase (CAT), superoxide dismutase (SOD), glutathione (GSH), prostaglandin E2 (PGE2) and malondialdehyde (MDA) activities of the gastric tissue intoxicated by ethanol. (biomedcentral.com)
  • In adults and children, it is used to treat conditions such as reflux esophagitis (tissue damage caused by reflux of gastric contents into the esophagus) and symptoms of gastro esophageal reflux, or GERD. (plateaudrugs.com)
  • Determination of bile reflux in esophagus after cholecystectomy is possible and informative. (patcue.com)
  • The objective of this study was to evaluate the effect of formulation variables on the release properties, floating lag time, and hardness, when developing floating tablets of Ranitidine hydrochloride, by the statistical optimization technique. (jyoungpharm.in)
  • The results demonstrate the feasibility of the model in the development of floating tablets containing Ranitidine hydrochloride. (jyoungpharm.in)