The use of IONIZING RADIATION to treat malignant NEOPLASMS and some benign conditions.
The total amount of radiation absorbed by tissues as a result of radiotherapy.
Radiotherapy where there is improved dose homogeneity within the tumor and reduced dosage to uninvolved structures. The precise shaping of dose distribution is achieved via the use of computer-controlled multileaf collimators.
Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
CONFORMAL RADIOTHERAPY that combines several intensity-modulated beams to provide improved dose homogeneity and highly conformal dose distributions.
Computer-assisted mathematical calculations of beam angles, intensities of radiation, and duration of irradiation in radiotherapy.
Radiotherapy using high-energy (megavolt or higher) ionizing radiation. Types of radiation include gamma rays, produced by a radioisotope within a teletherapy unit; x-rays, electrons, protons, alpha particles (helium ions) and heavy charged ions, produced by particle acceleration; and neutrons and pi-mesons (pions), produced as secondary particles following bombardment of a target with a primary particle.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
Administration of the total dose of radiation (RADIATION DOSAGE) in parts, at timed intervals.
Harmful effects of non-experimental exposure to ionizing or non-ionizing radiation in VERTEBRATES.
Computer systems or programs used in accurate computations for providing radiation dosage treatment to patients.
The use of pre-treatment imaging modalities to position the patient, delineate the target, and align the beam of radiation to achieve optimal accuracy and reduce radiation damage to surrounding non-target tissues.
A subspecialty of medical oncology and radiology concerned with the radiotherapy of cancer.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A radiological stereotactic technique developed for cutting or destroying tissue by high doses of radiation in place of surgical incisions. It was originally developed for neurosurgery on structures in the brain and its use gradually spread to radiation surgery on extracranial structures as well. The usual rigid needles or probes of stereotactic surgery are replaced with beams of ionizing radiation directed toward a target so as to achieve local tissue destruction.
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.
A collective term for interstitial, intracavity, and surface radiotherapy. It uses small sealed or partly-sealed sources that may be placed on or near the body surface or within a natural body cavity or implanted directly into the tissues.
The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Treatment that combines chemotherapy with radiotherapy.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
Tumors or cancer of the NASOPHARYNX.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
The ability of some cells or tissues to survive lethal doses of IONIZING RADIATION. Tolerance depends on the species, cell type, and physical and chemical variables, including RADIATION-PROTECTIVE AGENTS and RADIATION-SENSITIZING AGENTS.
Organs which might be damaged during exposure to a toxin or to some form of therapy. It most frequently refers to healthy organs located in the radiation field during radiation therapy.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Tumors or cancer of the LUNG.
Tumors or cancer of the RECTUM.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Devices which accelerate electrically charged atomic or subatomic particles, such as electrons, protons or ions, to high velocities so they have high kinetic energy.
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
The exposure of the head to roentgen rays or other forms of radioactivity for therapeutic or preventive purposes.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by SCINTILLATION COUNTING.
Tumors or cancer of the PROSTATE.
Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
Tumors or cancer of the pelvic region.
Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.
Removal of only enough breast tissue to ensure that the margins of the resected surgical specimen are free of tumor.
Tumors or cancer of the human BREAST.
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
A cutaneous inflammatory reaction occurring as a result of exposure to ionizing radiation.
The use of a heavy ion particle beam for radiotherapy, such as the HEAVY IONS of CARBON.
Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation.
An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)
Techniques, procedures, and therapies carried out on diseased organs in such a way to avoid complete removal of the organ and preserve the remaining organ function.
Decreased salivary flow.
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
A type of high-energy radiotherapy using a beam of gamma-radiation produced by a radioisotope source encapsulated within a teletherapy unit.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Elements of limited time intervals, contributing to particular results or situations.
Spinal neoplasms are abnormal growths or tumors that develop on or in the spinal cord or surrounding tissues.
Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)
A malignant epithelial tumor with a glandular organization.
Unstable isotopes of cobalt that decay or disintegrate emitting radiation. Co atoms with atomic weights of 54-64, except 59, are radioactive cobalt isotopes.
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.
External or interstitial irradiation to treat lymphomas (e.g., Hodgkin's and non-Hodgkin's lymphomas) and lymph node metastases and also some autoimmune diseases, such as rheumatoid arthritis.
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
Tumors or cancer of the UTERINE CERVIX.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other, e.g. military, purposes.
A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Surgical procedure to remove one or both breasts.
Unstable isotopes of iridium that decay or disintegrate emitting radiation. Ir atoms with atomic weights 182-190, 192, and 194-198 are radioactive iridium isotopes.
Necrosis of bone following radiation injury.
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)
The space or compartment surrounded by the pelvic girdle (bony pelvis). It is subdivided into the greater pelvis and LESSER PELVIS. The pelvic girdle is formed by the PELVIC BONES and SACRUM.
Tumors or cancer of the ESOPHAGUS.
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.
Thoracic neoplasms are tumors that develop in the chest region, including the lungs, pleura, mediastinum, and other structures.
The total amount (cell number, weight, size or volume) of tumor cells or tissue in the body.
Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.
Moving a patient into a specific position or POSTURE to facilitate examination, surgery, or for therapeutic purposes.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Mistakes committed in the preparations for radiotherapy, including errors in positioning of patients, alignment radiation beams, or calculation of radiation doses.
Materials used as reference points for imaging studies.
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Total or partial excision of the larynx.
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Compounds which inhibit or antagonize the biosynthesis or actions of androgens.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Tumors or cancer of the OROPHARYNX.
Positively-charged atomic nuclei that have been stripped of their electrons. These particles have one or more units of electric charge and a mass exceeding that of the Helium-4 nucleus (alpha particle).
Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation.
An alkylating agent of value against both hematologic malignancies and solid tumors.
The use of an external beam of PROTONS as radiotherapy.
Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.
Tumors or cancer of the HYPOPHARYNX.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Therapeutic act or process that initiates a response to a complete or partial remission level.
Tumors or cancer located in bone tissue or specific BONES.
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
An INFLAMMATION of the MUCOSA with burning or tingling sensation. It is characterized by atrophy of the squamous EPITHELIUM, vascular damage, inflammatory infiltration, and ulceration. It usually occurs at the mucous lining of the MOUTH, the GASTROINTESTINAL TRACT or the airway due to chemical irritations, CHEMOTHERAPY, or radiation therapy (RADIOTHERAPY).
Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.
Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS).
Tumors or cancer of the NOSE.
ELECTROMAGNETIC RADIATION or particle radiation (high energy ELEMENTARY PARTICLES) capable of directly or indirectly producing IONS in its passage through matter. The wavelengths of ionizing electromagnetic radiation are equal to or smaller than those of short (far) ultraviolet radiation and include gamma and X-rays.
Combined chemotherapy and radiotherapy given to augment some other form of treatment such as surgery. It is commonly used in the therapy of cancer.
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)
Vinblastine derivative with antineoplastic activity against CANCER. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS).
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)
An organoplatinum compound that possesses antineoplastic activity.
INFLAMMATION of the soft tissues of the MOUTH, such as MUCOSA; PALATE; GINGIVA; and LIP.
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
The science concerned with problems of radiation protection relevant to reducing or preventing radiation exposure, and the effects of ionizing radiation on humans and their environment.
The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.
Three-dimensional computed tomographic imaging with the added dimension of time, to follow motion during imaging.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).
Study of the scientific principles, mechanisms, and effects of the interaction of ionizing radiation with living matter. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
Total mastectomy with axillary node dissection, but with preservation of the pectoral muscles.
Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
Institutions specializing in the care of cancer patients.
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Antimetabolites that are useful in cancer chemotherapy.
Abdominal neoplasms refer to tumors or growths that develop in the abdominal cavity or its organs.
Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.
A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)
The return of a sign, symptom, or disease after a remission.
Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
The surgical removal of the eyeball leaving the eye muscles and remaining orbital contents intact.
The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)
Deoxycytidine is a nucleoside that is a building block of DNA and is involved in DNA replication and repair.
Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.
Tumors or cancer of the ANAL CANAL.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
A cell line derived from cultured tumor cells.
Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
A performance measure for rating the ability of a person to perform usual activities, evaluating a patient's progress after a therapeutic procedure, and determining a patient's suitability for therapy. It is used most commonly in the prognosis of cancer therapy, usually after chemotherapy and customarily administered before and after therapy. It was named for Dr. David A. Karnofsky, an American specialist in cancer chemotherapy.
Tumors or cancer of the PHARYNX.
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)
Benign and malignant intra-axial tumors of the MESENCEPHALON; PONS; or MEDULLA OBLONGATA of the BRAIN STEM. Primary and metastatic neoplasms may occur in this location. Clinical features include ATAXIA, cranial neuropathies (see CRANIAL NERVE DISEASES), NAUSEA, hemiparesis (see HEMIPLEGIA), and quadriparesis. Primary brain stem neoplasms are more frequent in children. Histologic subtypes include GLIOMA; HEMANGIOBLASTOMA; GANGLIOGLIOMA; and EPENDYMOMA.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The period following a surgical operation.
Primary or metastatic neoplasms of the CEREBELLUM. Tumors in this location frequently present with ATAXIA or signs of INTRACRANIAL HYPERTENSION due to obstruction of the fourth ventricle. Common primary cerebellar tumors include fibrillary ASTROCYTOMA and cerebellar HEMANGIOBLASTOMA. The cerebellum is a relatively common site for tumor metastases from the lung, breast, and other distant organs. (From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141)
Surgical excision of one or more lymph nodes. Its most common use is in cancer surgery. (From Dorland, 28th ed, p966)
Neoplasms of the bony orbit and contents except the eyeball.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Penetrating, high-energy electromagnetic radiation emitted from atomic nuclei during NUCLEAR DECAY. The range of wavelengths of emitted radiation is between 0.1 - 100 pm which overlaps the shorter, more energetic hard X-RAYS wavelengths. The distinction between gamma rays and X-rays is based on their radiation source.
Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)
Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)
Discrete concentrations of energy, apparently massless elementary particles, that move at the speed of light. They are the unit or quantum of electromagnetic radiation. Photons are emitted when electrons move from one energy state to another. (From Hawley's Condensed Chemical Dictionary, 11th ed)
The ratio of radiation dosages required to produce identical change based on a formula comparing other types of radiation with that of gamma or roentgen rays.
A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).
Tumors or cancer of the EYE.
Abnormally high temperature intentionally induced in living things regionally or whole body. It is most often induced by radiation (heat waves, infra-red), ultrasound, or drugs.
Dissection in the neck to remove all disease tissues including cervical LYMPH NODES and to leave an adequate margin of normal tissue. This type of surgery is usually used in tumors or cervical metastases in the head and neck. The prototype of neck dissection is the radical neck dissection described by Crile in 1906.
Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.
Pathological processes of the male URINARY TRACT and the reproductive system (GENITALIA, MALE).
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
Irradiation of one half or both halves of the body in the treatment of disseminated cancer or widespread metastases. It is used to treat diffuse metastases in one session as opposed to multiple fields over an extended period. The more frequent treatment modalities are upper hemibody irradiation (UHBI) or lower hemibody irradiation (LHBI). Less common is mid-body irradiation (MBI). In the treatment of both halves of the body sequentially, hemibody irradiation permits radiotherapy of the whole body with larger doses of radiation than could be accomplished with WHOLE-BODY IRRADIATION. It is sometimes called "systemic" hemibody irradiation with reference to its use in widespread cancer or metastases. (P. Rubin et al. Cancer, Vol 55, p2210, 1985)
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Leukopenia is a medical condition characterized by a decrease in the number of white blood cells in the body.
Remnant of a tumor or cancer after primary, potentially curative therapy. (Dr. Daniel Masys, written communication)
Experimentally produced harmful effects of ionizing or non-ionizing RADIATION in CHORDATA animals.
Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
Difficulty in SWALLOWING which may result from neuromuscular disorder or mechanical obstruction. Dysphagia is classified into two distinct types: oropharyngeal dysphagia due to malfunction of the PHARYNX and UPPER ESOPHAGEAL SPHINCTER; and esophageal dysphagia due to malfunction of the ESOPHAGUS.
Tumors of cancer of the EYELIDS.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.

Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients. (1/2648)

18-Fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) has previously been used successfully to image primary and metastatic breast cancer. In this pilot study, 19 breast cancer patients with symptoms/signs referrable to the brachial plexus were evaluated with 18FDG-PET. In 11 cases computerized tomography (CT) scanning was also performed. Of the 19 patients referred for PET study, 14 had abnormal uptake of 18FDG in the region of the symptomatic plexus. Four patients had normal PET studies and one had increased FDG uptake in the chest wall that accounted for her axillary pain. CT scans were performed in 9 of the 14 patients who had positive brachial plexus PET studies; six of these were either normal or showed no clear evidence of recurrent disease, while three CTs demonstrated clear brachial plexus involvement. Of two of the four patients with normal PET studies, one has had complete resolution of symptoms untreated while the other was found to have cervical disc herniation on magnetic resonance imaging (MRI) scan. The remaining two patients almost certainly had radiation-induced plexopathy and had normal CT, MRI and PET study. These data suggest that 18FDG-PET scanning is a useful tool in evaluation of patients with suspected metastatic plexopathy, particularly if other imaging studies are normal. It may also be useful in distinguishing between radiation-induced and metastatic plexopathy.  (+info)

Quality of life and performance in advanced head and neck cancer patients on concomitant chemoradiotherapy: a prospective examination. (2/2648)

PURPOSE: To prospectively evaluate performance and quality of life (QOL) in advanced-stage head and neck cancer (HNC) patients on a curative-intent, concomitant-chemoradiotherapy (CT/XRT) (twice-daily radiation, fluorouracil, hydroxyurea, and cisplatin) regimen aimed at improving locoregional control, survival, and QOL. PATIENTS AND METHODS: Sixty-four patients were assessed before, during, and at 3-month intervals after treatment. Standardized measures of QOL (Functional Assessment of Cancer Therapy-Head and Neck), performance (Performance Status Scale for Head and Neck Cancer Patients and Karnofsky Performance Status Rating Scale), and patient-reported symptoms (McMaster University Head and Neck Radiotherapy Questionnaire) were administered. RESULTS: Acute treatment toxicities were severe, with declines in virtually all QOL and functional domains. Marked improvement was seen by 12 months; general functional and physical measures returned to baseline levels of good to excellent. Although up to a third of the patients continued to report problems with swallowing, hoarseness, and mouth pain, these difficulties were present in similar magnitudes before treatment. The following symptoms were more frequent at 12 months: dry mouth (58% v 17%), difficulties tasting (32% v 8%), and soft food diet (82% v 42%). Twelve-month diet was not related to pretreatment functioning, disease, treatment, or patient characteristics. Twelve-month QOL was best predicted by pretreatment QOL, with very little relationship to residual side effects or functional impairments. Small numbers of patients in four of the five disease sites precluded examination of outcome by site. CONCLUSION: These data support the feasibility of intense CT/XRT as primary treatment for advanced HNC. Results confirm acute toxicity but indicate that many of the treatment-related performance and QOL declines resolve by 12 months. The persistent inability to eat a full range of foods warrants further attention and monitoring.  (+info)

p53 and p16INK4A mutations during the progression of glomus tumor. (3/2648)

Glomus tumors are significantly rare tumors of carotid body. The great majority of these tumors are benign in character. Here we present two brothers with hereditary glomus jugulare tumor who had consanguineous parents. Radiotherapy was applied approximately 8 and 10 years ago for treatment in both cases. Eight years later, one of these cases came to our notice due to relapse. The mutation pattern of p53, p57KIP2, p16INK4A and p15NK4B genes which have roles in the cell cycle, was analyzed in tumor samples obtained from the two affected cases in the initial phase and from one of these cases at relapse. The DNA sample obtained from the case in initial diagnosis phase revealed no p53, p57KIP2, p16INK4A or p15INK4B mutation. He is still in remission phase. Despite the lack of p53, p57KIP2, p16INK4A and p15INK4B mutation at initial diagnosis the tumor DNA of the other case in relapse revealed p53 codon 243 (ATG-->ATC; met-->ile) and p16 codon 97 (GAC-->AAC; asp-->asn) missense point mutations. No loss of heterozygosity in p53 and p16INK4A was observed by microsatellite analysis of tumoral tissues in these cases. P53 and p16INK4A mutations observed in relapse phase were in conserved regions of both genes. No previous reports have been published with these mutations in glomus tumor during progression. The mutation observed in this case may due to radiotherapy. In spite of this possibility, the missense point mutations in conserved region of p53 and p16INK4A genes may indicate the role of p53 and p16INK4A in tumor progression of glomus tumors.  (+info)

Radiation induced endothelial cell retraction in vitro: correlation with acute pulmonary edema. (4/2648)

We determined the effects of low dose radiation (<200 cGy) on the cell-cell integrity of confluent monolayers of pulmonary microvascular endothelial cells (PMEC). We observed dose- and time-dependent reversible radiation induced injuries to PMEC monolayers characterized by retraction (loss of cell-cell contact) mediated by cytoskeletal F-actin reorganization. Radiation induced reorganization of F-actin microfilament stress fibers was observed > or =30 minutes post irradiation and correlated positively with loss of cell-cell integrity. Cells of irradiated monolayers recovered to form contact inhibited monolayers > or =24 hours post irradiation; concomitantly, the depolymerized microfilaments organized to their pre-irradiated state as microfilament stress fibers arrayed parallel to the boundaries of adjacent contact-inhibited cells. Previous studies by other investigators have measured slight but significant increases in mouse lung wet weight >1 day post thoracic or whole body radiation (> or =500 cGy). Little or no data is available concerning time intervals <1 day post irradiation, possibly because of the presumption that edema is mediated, at least in part, by endothelial cell death or irreversible loss of barrier permeability functions which may only arise 1 day post irradiation. However, our in vitro data suggest that loss of endothelial barrier function may occur rapidly and at low dose levels (< or =200 cGy). Therefore, we determined radiation effects on lung wet weight and observed significant increases in wet weight (standardized per dry weight or per mouse weight) in < or =5 hours post thoracic exposure to 50 200 cGy x-radiation. We suggest that a single fraction of radiation even at low dose levels used in radiotherapy, may induce pulmonary edema by a reversible loss of endothelial cell-cell integrity and permeability barrier function.  (+info)

When to consider radiation therapy for your patient. (5/2648)

Radiation therapy can be an effective treatment modality for both malignant and benign disease. While radiation can be given as primary treatment, it may also be used pre- or postoperatively, with or without other forms of therapy. Radiation therapy is often curative but is sometimes palliative. There are many methods of delivering radiation effectively. Often, patients tolerate irradiation well without significant complications, and organ function is preserved. To ensure that all patients with cancer have the opportunity to consider all treatment options, family physicians should be aware of the usefulness of radiation therapy.  (+info)

Diagnostic and therapeutic approaches for nonmetastatic breast cancer in Canada, and their associated costs. (6/2648)

In an era of fiscal restraint, it is important to evaluate the resources required to diagnose and treat serious illnesses. As breast cancer is the major malignancy affecting Canadian women, Statistics Canada has analysed the resources required to manage this disease in Canada, and the associated costs. Here we report the cost of initial diagnosis and treatment of nonmetastatic breast cancer, including adjuvant therapies. Treatment algorithms for Stages I, II, and III of the disease were derived by age group (< 50 or > or = 50 years old), principally from Canadian cancer registry data, supplemented, where necessary, by the results of surveys of Canadian oncologists. Data were obtained on breast cancer incidence by age, diagnostic work-up, stage at diagnosis, initial treatment, follow-up practice, duration of hospitalization and direct care costs. The direct health care costs associated with 'standard' diagnostic and therapeutic approaches were calculated for a cohort of 17,700 Canadian women diagnosed in 1995. Early stage (Stages I and II) breast cancer represented 87% of all incident cases, with 77% of cases occurring in women > or = 50 years. Variations were noted in the rate of partial vs total mastectomy, according to stage and age group. Direct costs for diagnosis and initial treatment ranged from $8014 for Stage II women > or = 50 years old, to $10,897 for Stage III women < 50 years old. Except for Stage III women < 50 years old, the largest expenditure was for hospitalization for surgery, followed by radiotherapy costs. Chemotherapy was the largest cost component for Stage III women < 50 years old. This report describes the cost of diagnosis and initial treatment of nonmetastatic breast cancer in Canada, assuming current practice patterns. A second report will describe the lifetime costs of treating all stages of breast cancer. These data will then be incorporated into Statistics Canada's Population Health Model (POHEM) to perform cost-effectiveness studies of new therapeutic interventions for breast cancer, such as the cost-effectiveness of day surgery, or of radiotherapy to all breast cancer patients undergoing breast surgery.  (+info)

In vitro assessment of Lipiodol-targeted radiotherapy for liver and colorectal cancer cell lines. (7/2648)

Intra-arterial Lipiodol has been used to deliver targeted therapies to primary, and some metastatic, liver cancers. Targeted radiotherapy has been used by substituting the iodine in Lipiodol with 131Iodine (131I). Early clinical results are encouraging, but the variable response may partly depend on local pharmacokinetics. This study evaluated the in vitro cytotoxic effects of 131I-Lipiodol on human hepatocellular carcinoma (Hep-G2), human colorectal metastatic cancer (SW620), human colorectal hepatic cancer (LoVo) and human umbilical vein endothelial cells (HUVEC) cell lines. The cell cultures were exposed to 131I-Lipiodol for 48 h, following which cell counts and viability were assessed by haemocytometer, S-Rhodamine uptake and radioactivity assay. The effect of exposure to control Lipiodol, 131I-Lipiodol and 131I alone was evaluated. 131I-Lipiodol was cytotoxic against all the cancer cell lines but not against the non-malignant (HUVEC) cell line. The cytotoxicity effects were very similar in all the cancer cell lines. There were no cytotoxic effects following exposure to plain 131I in any of the cell lines (malignant and non-malignant). A similar trend was seen with radioactivity counts using a gamma counter. The cytotoxic effect of 131I-Lipiodol had a graded effect with an increase in cytotoxicity following the increase in the radioactive dose. This study showed that there was a marked cytotoxic effect by 131I-Lipiodol on all the cancer cell lines. There was no difference between the controls and the 131Iodine. This suggests that effective 131I-Lipiodol targeted therapy is dependent on the uptake and retention of Lipiodol by malignant cells.  (+info)

Correlation of bcl-2 rearrangement with clinical characteristics and outcome in indolent follicular lymphoma. (8/2648)

The t(14;18) translocation, which involves the bcl-2 oncogene, occurs in follicular lymphomas (FL) at two common sites: the major breakpoint region (MBR) and the minor cluster region (mcr). The biological and clinical significance of these breakpoints is unknown. The bcl-2 breakpoint site was determined in 247 previously untreated patients (49% men; median age 52 years) with indolent FL (155 grade I, 83 grade II, and 8 grade III) to correlate it with pretreatment characteristics, response, and outcome. The bcl-2 breakpoint site was determined by a polymerase chain reaction method of peripheral blood (all cases), bone marrows (149 cases), and fresh lymph node biopsy specimens (68 cases). The breakpoint site occurred at MBR in 175 cases (71%) and at mcr in 27 (11%). In 45 cases (18%), no breakpoint was detected (germline). No significant relationship was found between the rearrangements and the expression of BLC-2 and BAX proteins. Patients' germline for MBR and mcr tended to present more frequently with stage IV disease and higher beta2-microglobulin (beta2M) levels, whereas mcr-rearranged patients presented more frequently with early stage and normal beta2M. The complete response rate of germline patients was significantly lower than that of MBR and mcr patients. An estimated 3-year failure-free survival (FFS) for mcr, MBR, and germline cases was 95%, 76%, and 57%, respectively (P <.001). The bcl-2 breakpoint site was independent of serum beta2M and lactate dehydrogenase in its correlation with FFS. In conclusion, the bcl-2 rearrangement site is an important prognostic factor in indolent FL, useful to identify patients who may require different treatment.  (+info)

Radiation injuries refer to damage to living tissue caused by exposure to ionizing radiation. Ionizing radiation is a type of energy that has enough energy to remove tightly bound electrons from atoms, creating ions. This can cause damage to cells and tissues, leading to a range of symptoms and health problems. Radiation injuries can occur from a variety of sources, including medical procedures such as radiation therapy, nuclear accidents, and exposure to radioactive materials. The severity of radiation injuries depends on the dose of radiation received, the duration of exposure, and the type of tissue affected. Symptoms of radiation injuries can include skin burns, hair loss, nausea, vomiting, diarrhea, fatigue, and an increased risk of developing cancer. In severe cases, radiation injuries can be life-threatening and may require medical intervention, such as surgery or supportive care. Treatment for radiation injuries depends on the severity of the injury and the underlying cause. In some cases, treatment may involve medications to manage symptoms, wound care, and physical therapy. In more severe cases, surgery may be necessary to remove damaged tissue or repair injuries.

Head and neck neoplasms refer to tumors that develop in the head and neck region of the body. These tumors can be benign (non-cancerous) or malignant (cancerous) and can affect any part of the head and neck, including the mouth, nose, throat, sinuses, salivary glands, thyroid gland, and neck lymph nodes. Head and neck neoplasms can be further classified based on the type of tissue they arise from, such as squamous cell carcinoma (which develops from the squamous cells that line the inside of the mouth and throat), adenoid cystic carcinoma (which develops from the glands that produce mucus), and salivary gland tumors (which develop from the salivary glands). The treatment for head and neck neoplasms depends on the type, size, location, and stage of the tumor, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, and immunotherapy. Early detection and treatment are crucial for improving the prognosis and reducing the risk of complications.

Neoplasm recurrence, local refers to the return of cancer cells to the original site of the tumor after treatment. This can occur even if the cancer has been completely removed through surgery or other treatments. Local recurrence is typically treated with additional surgery, radiation therapy, or chemotherapy, depending on the type and stage of the cancer. It is important to note that local recurrence does not necessarily mean that the cancer has spread to other parts of the body.

Nasopharyngeal neoplasms refer to tumors that develop in the nasopharynx, which is the part of the throat located at the back of the nose and the top of the throat. These tumors can be either benign or malignant, and they can occur in any part of the nasopharynx, including the nasopharyngeal epithelium, the lymphoid tissue, and the salivary glands. Nasopharyngeal neoplasms are relatively uncommon, but they can be aggressive and difficult to treat. Some of the most common types of nasopharyngeal neoplasms include nasopharyngeal carcinoma, which is a type of head and neck cancer that is particularly common in certain parts of the world, such as Southeast Asia and Southern China, and nasopharyngeal angiofibroma, which is a benign tumor that is more common in adolescent boys. The symptoms of nasopharyngeal neoplasms can vary depending on the location and size of the tumor, but they may include nasal congestion, difficulty swallowing, ear pain, hearing loss, and a persistent sore throat. Diagnosis typically involves a combination of physical examination, imaging studies, and biopsy. Treatment for nasopharyngeal neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. The choice of treatment depends on the type and stage of the tumor, as well as the overall health of the patient.

Brain neoplasms, also known as brain tumors, are abnormal growths of cells in the brain. They can be either benign (non-cancerous) or malignant (cancerous). Brain tumors can occur in any part of the brain and can be primary (originating from brain cells) or secondary (spreading from other parts of the body to the brain). Symptoms of brain neoplasms can vary depending on the location and size of the tumor, but may include headaches, seizures, changes in vision or hearing, difficulty with balance or coordination, and changes in personality or behavior. Diagnosis of brain neoplasms typically involves a combination of imaging tests such as MRI or CT scans, as well as a biopsy to confirm the presence of cancer cells. Treatment options for brain neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. The specific treatment plan will depend on the type, location, and stage of the tumor, as well as the overall health of the patient.

Carcinoma, Squamous Cell is a type of cancer that originates in the squamous cells, which are thin, flat cells that line the surface of the body. Squamous cells are found in the skin, mouth, throat, lungs, and other organs. Carcinoma, Squamous Cell can develop in any part of the body where squamous cells are present, but it is most commonly found in the head and neck, lungs, and skin. The exact cause of Squamous Cell Carcinoma is not always clear, but it is often associated with exposure to certain substances, such as tobacco smoke, alcohol, and certain chemicals. It can also develop as a result of chronic inflammation or infection, such as HPV (human papillomavirus) infection in the cervix. Symptoms of Squamous Cell Carcinoma can vary depending on the location of the tumor, but may include a persistent sore or lesion that does not heal, a change in the appearance of the skin or mucous membranes, difficulty swallowing or breathing, and unexplained weight loss. Treatment for Squamous Cell Carcinoma typically involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to kill any remaining cancer cells. In some cases, targeted therapy or immunotherapy may also be used. The prognosis for Squamous Cell Carcinoma depends on the stage of the cancer at the time of diagnosis and the overall health of the patient.

Lung neoplasms refer to abnormal growths or tumors that develop in the lungs. These growths can be either benign (non-cancerous) or malignant (cancerous). Lung neoplasms can occur in any part of the lung, including the bronchi, bronchioles, and alveoli. Lung neoplasms can be further classified based on their type, including: 1. Primary lung neoplasms: These are tumors that develop in the lungs and do not spread to other parts of the body. 2. Secondary lung neoplasms: These are tumors that develop in the lungs as a result of cancer that has spread from another part of the body. 3. Benign lung neoplasms: These are non-cancerous tumors that do not spread to other parts of the body. 4. Malignant lung neoplasms: These are cancerous tumors that can spread to other parts of the body. Some common types of lung neoplasms include lung adenocarcinoma, squamous cell carcinoma, large cell carcinoma, and small cell carcinoma. The diagnosis of lung neoplasms typically involves a combination of imaging tests, such as chest X-rays and CT scans, and a biopsy to examine a sample of tissue from the tumor. Treatment options for lung neoplasms depend on the type, size, and location of the tumor, as well as the overall health of the patient.

Rectal neoplasms refer to abnormal growths or tumors that develop in the rectum, which is the final section of the large intestine. These neoplasms can be either benign or malignant, and they can range in size and location within the rectum. Benign rectal neoplasms, also known as polyps, are non-cancerous growths that typically do not spread to other parts of the body. They can be either pedunculated, meaning they have a stalk that attaches them to the rectal wall, or sessile, meaning they are attached directly to the rectal wall. Malignant rectal neoplasms, also known as rectal cancers, are cancerous tumors that can invade nearby tissues and spread to other parts of the body through the bloodstream or lymphatic system. Rectal cancers can be either adenocarcinomas, which are the most common type, or squamous cell carcinomas, which are less common. Rectal neoplasms can cause a variety of symptoms, including rectal bleeding, changes in bowel habits, pain or discomfort in the rectum, and a feeling of incomplete bowel movements. Diagnosis typically involves a combination of physical examination, imaging studies, and biopsy. Treatment options for rectal neoplasms depend on the type, size, and location of the tumor, as well as the overall health of the patient.

Cisplatin is a chemotherapy drug that is commonly used to treat various types of cancer, including ovarian, testicular, bladder, and lung cancer. It works by binding to the DNA of cancer cells, which prevents them from dividing and growing. Cisplatin is usually administered intravenously and can cause a range of side effects, including nausea, vomiting, hair loss, and damage to the kidneys and hearing. It is important to note that cisplatin is not effective for all types of cancer and may not be suitable for everyone. The use of cisplatin should be determined by a healthcare professional based on the individual's specific medical needs and circumstances.

Prostatic neoplasms refer to tumors that develop in the prostate gland, which is a small gland located in the male reproductive system. These tumors can be either benign (non-cancerous) or malignant (cancerous). Benign prostatic neoplasms, also known as benign prostatic hyperplasia (BPH), are the most common type of prostatic neoplasm and are typically associated with an increase in the size of the prostate gland. Malignant prostatic neoplasms, on the other hand, are more serious and can spread to other parts of the body if left untreated. The most common type of prostate cancer is adenocarcinoma, which starts in the glandular cells of the prostate. Other types of prostatic neoplasms include sarcomas, which are rare and start in the connective tissue of the prostate, and carcinoid tumors, which are rare and start in the neuroendocrine cells of the prostate.

Radiation pneumonitis is a condition that occurs when the lungs are exposed to high levels of radiation, such as during radiation therapy for cancer. It is a type of inflammation that affects the lungs and can cause symptoms such as coughing, shortness of breath, chest pain, and fever. In severe cases, radiation pneumonitis can lead to lung fibrosis, a condition in which the lungs become scarred and stiff, making it difficult to breathe. Treatment for radiation pneumonitis may include medications to reduce inflammation and manage symptoms, as well as oxygen therapy to help the lungs function properly.

Pelvic neoplasms refer to tumors or abnormal growths that develop in the pelvic region, which includes the bones, muscles, ligaments, and organs of the pelvis. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) in nature. Some common types of pelvic neoplasms include ovarian cancer, uterine cancer, cervical cancer, vaginal cancer, and prostate cancer. These neoplasms can cause a variety of symptoms, such as pelvic pain, difficulty urinating or having a bowel movement, abnormal vaginal bleeding, and a feeling of fullness in the abdomen. Diagnosis of pelvic neoplasms typically involves a combination of physical examination, imaging tests such as CT scans or MRI, and biopsy to confirm the presence of cancer cells. Treatment options for pelvic neoplasms depend on the type and stage of the cancer, as well as the patient's overall health and preferences. They may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Laryngeal neoplasms refer to abnormal growths or tumors that develop in the larynx, which is the voice box located in the throat. These neoplasms can be benign (non-cancerous) or malignant (cancerous) in nature. Benign laryngeal neoplasms include polyps, papillomas, and cysts, which can cause hoarseness, difficulty swallowing, and other symptoms. Malignant laryngeal neoplasms, such as squamous cell carcinoma, can spread to other parts of the body and are more serious. Diagnosis of laryngeal neoplasms typically involves a combination of physical examination, imaging studies, and biopsy. Treatment options depend on the type, size, and location of the neoplasm, as well as the overall health of the patient. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Breast neoplasms refer to abnormal growths or tumors in the breast tissue. These growths can be benign (non-cancerous) or malignant (cancerous). Benign breast neoplasms are usually not life-threatening, but they can cause discomfort or cosmetic concerns. Malignant breast neoplasms, on the other hand, can spread to other parts of the body and are considered a serious health threat. Some common types of breast neoplasms include fibroadenomas, ductal carcinoma in situ (DCIS), invasive ductal carcinoma, and invasive lobular carcinoma.

Hodgkin disease, also known as Hodgkin lymphoma, is a type of cancer that affects the lymphatic system, which is a part of the immune system. It typically starts in the lymph nodes, which are small, bean-shaped organs that help fight infections and diseases. In Hodgkin disease, abnormal cells called Reed-Sternberg cells grow and multiply uncontrollably in the lymph nodes, causing them to become swollen and painful. The cancer can also spread to other parts of the body, such as the spleen, liver, and bone marrow. There are several different types of Hodgkin disease, which are classified based on the appearance of the Reed-Sternberg cells and the presence of other cells in the affected lymph nodes. Treatment for Hodgkin disease typically involves a combination of chemotherapy, radiation therapy, and/or stem cell transplantation, depending on the stage and type of the cancer.

Radiodermatitis is a type of skin inflammation that occurs as a result of exposure to ionizing radiation. It is also known as radiation dermatitis or radiation-induced dermatitis. The condition can affect any part of the body that has been exposed to radiation, but it is most commonly seen on the skin of the face, neck, and hands. Radiodermatitis can be caused by a variety of sources, including medical treatments such as radiation therapy for cancer, as well as exposure to radiation from nuclear accidents or other sources. The condition can range from mild to severe, and symptoms may include redness, swelling, itching, and pain. In severe cases, radiodermatitis can lead to blistering, ulceration, and scarring. Treatment for radiodermatitis typically involves managing symptoms and preventing further skin damage. This may include using moisturizers, anti-inflammatory medications, and antibiotics to treat infections. In some cases, a skin graft may be necessary to repair severe damage. It is important to note that prevention is key, and minimizing exposure to ionizing radiation is the best way to prevent radiodermatitis.

Neoplasms, radiation-induced are abnormal growths of cells that are caused by exposure to ionizing radiation. Ionizing radiation is a type of energy that has enough force to remove tightly bound electrons from atoms, causing the atoms to become ionized. This type of radiation is capable of damaging DNA and other cellular structures, which can lead to mutations and the development of cancer. Radiation-induced neoplasms can occur in any part of the body that has been exposed to ionizing radiation, including the skin, lungs, thyroid gland, and bone marrow. The risk of developing a radiation-induced neoplasm increases with the dose of radiation received and the duration of exposure. In addition, certain factors such as age, gender, and genetic predisposition can also affect the risk of developing a radiation-induced neoplasm. Treatment for radiation-induced neoplasms depends on the type and stage of the cancer, as well as the location and extent of the radiation exposure. Options may include surgery, radiation therapy, chemotherapy, and targeted therapy. It is important for individuals who have been exposed to ionizing radiation to be monitored for the development of radiation-induced neoplasms, as early detection and treatment can improve outcomes.

Vincristine is a chemotherapy drug that is used to treat various types of cancer, including leukemia, lymphoma, and neuroblastoma. It works by interfering with the growth and division of cancer cells, which can slow or stop the growth of tumors. Vincristine is usually administered intravenously, and its side effects can include nausea, vomiting, hair loss, and damage to the nerves that control movement. It is also known by the brand name Oncovin.

In the medical field, "Neoplasms, Second Primary" refers to the development of a new cancer in a person who has already been diagnosed with one or more primary cancers. This type of cancer is also known as a "metastatic cancer" or a "secondary cancer." When a person develops a second primary cancer, it means that the cancer has spread from its original location to a new part of the body. This can happen through the bloodstream, lymphatic system, or other means of spread. The development of a second primary cancer can be a complex and challenging situation for both the patient and their healthcare team. Treatment options may depend on the type and location of the second cancer, as well as the patient's overall health and medical history.

Dacarbazine (DTIC-DMA) is a chemotherapy drug that is used to treat various types of cancer, including melanoma (a type of skin cancer), Hodgkin's lymphoma, and non-Hodgkin's lymphoma. It works by interfering with the growth and division of cancer cells, which can slow down or stop the growth of tumors. Dacarbazine is usually given intravenously (into a vein) or as an injection under the skin. It can cause side effects such as nausea, vomiting, hair loss, and low blood cell counts.

Xerostomia is a medical term used to describe a condition in which the mouth becomes excessively dry. It can be caused by a variety of factors, including dehydration, certain medications, radiation therapy to the head and neck, and certain medical conditions such as diabetes, Sjogren's syndrome, and HIV/AIDS. Xerostomia can cause a range of symptoms, including difficulty swallowing,, and an increased risk of tooth decay and gum disease. Treatment for xerostomia depends on the underlying cause and may include drinking plenty of fluids, using saliva substitutes, and avoiding certain medications that can cause dry mouth. In some cases, medical treatment may be necessary to address the underlying cause of xerostomia.

Procarbazine is a chemotherapy drug that is used to treat certain types of cancer, including Hodgkin's lymphoma, testicular cancer, and brain tumors. It works by interfering with the growth and division of cancer cells. Procarbazine is usually given in combination with other chemotherapy drugs and may be given orally or intravenously. It can cause side effects such as nausea, vomiting, loss of appetite, fatigue, and hair loss. It can also cause more serious side effects such as anemia, low white blood cell count, and damage to the liver or kidneys.

Fluorouracil is a chemotherapy drug that is commonly used to treat various types of cancer, including colorectal cancer, breast cancer, and head and neck cancer. It works by interfering with the production of DNA in cancer cells, which prevents them from dividing and growing. Fluorouracil is usually given intravenously or orally, and it can cause a range of side effects, including nausea, vomiting, diarrhea, and fatigue. In some cases, it can also cause more serious side effects, such as mouth sores, skin reactions, and anemia.

In the medical field, neoplasms refer to abnormal growths or tumors of cells that can occur in any part of the body. These growths can be either benign (non-cancerous) or malignant (cancerous). Benign neoplasms are usually slow-growing and do not spread to other parts of the body. They can cause symptoms such as pain, swelling, or difficulty moving the affected area. Examples of benign neoplasms include lipomas (fatty tumors), hemangiomas (vascular tumors), and fibromas (fibrous tumors). Malignant neoplasms, on the other hand, are cancerous and can spread to other parts of the body through the bloodstream or lymphatic system. They can cause a wide range of symptoms, depending on the location and stage of the cancer. Examples of malignant neoplasms include carcinomas (cancers that start in epithelial cells), sarcomas (cancers that start in connective tissue), and leukemias (cancers that start in blood cells). The diagnosis of neoplasms typically involves a combination of physical examination, imaging tests (such as X-rays, CT scans, or MRI scans), and biopsy (the removal of a small sample of tissue for examination under a microscope). Treatment options for neoplasms depend on the type, stage, and location of the cancer, as well as the patient's overall health and preferences.

Spinal neoplasms refer to tumors that develop in or on the spinal cord or spinal column. These tumors can be either benign (non-cancerous) or malignant (cancerous). Spinal neoplasms can cause a variety of symptoms, depending on their location and size. Some common symptoms include back pain, weakness or numbness in the arms or legs, difficulty walking or standing, and changes in bladder or bowel function. Diagnosis of spinal neoplasms typically involves a combination of imaging tests, such as MRI or CT scans, and a biopsy to confirm the presence of cancer cells. Treatment options for spinal neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches, depending on the type and location of the tumor, as well as the overall health of the patient.

Adenocarcinoma is a type of cancer that starts in the glandular cells of an organ or tissue. It is one of the most common types of cancer and can occur in many different parts of the body, including the lungs, breast, colon, rectum, pancreas, stomach, and thyroid gland. Adenocarcinomas typically grow slowly and may not cause symptoms in the early stages. However, as the cancer grows, it can invade nearby tissues and spread to other parts of the body through the bloodstream or lymphatic system. This can lead to more serious symptoms and a higher risk of complications. Treatment for adenocarcinoma depends on the location and stage of the cancer, as well as the overall health of the patient. Options may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these approaches. The goal of treatment is to remove or destroy the cancer cells and prevent them from spreading further.

Cobalt radioisotopes are radioactive isotopes of the element cobalt that are used in medical applications. These isotopes are typically produced by bombarding cobalt-59 with neutrons in a nuclear reactor or by using a cyclotron to accelerate protons onto a cobalt-59 target. There are several different cobalt radioisotopes that are used in medicine, including cobalt-57, cobalt-58, cobalt-60, and cobalt-67. Each of these isotopes has a different half-life (the time it takes for half of the atoms in a sample to decay) and emits different types of radiation. Cobalt radioisotopes are used in a variety of medical applications, including diagnostic imaging and radiation therapy. For example, cobalt-60 is often used as a source of gamma radiation in radiation therapy to treat cancer. Cobalt-57 is used in a diagnostic test called a "bone scan" to detect bone abnormalities, such as fractures or tumors. Cobalt-58 is used in a similar test called a "lung scan" to detect lung abnormalities. Overall, cobalt radioisotopes play an important role in the diagnosis and treatment of a variety of medical conditions.

Carcinoma, Non-Small-Cell Lung (NSCLC) is a type of lung cancer that starts in the cells that line the airways or the alveoli (tiny air sacs) in the lungs. NSCLC is the most common type of lung cancer, accounting for about 85% of all lung cancer cases. NSCLC is further classified into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. Adenocarcinoma is the most common subtype of NSCLC and is often associated with long-term exposure to tobacco smoke or other environmental factors. Squamous cell carcinoma is also associated with smoking, while large cell carcinoma is less common and can occur in both smokers and non-smokers. Treatment options for NSCLC depend on the stage of the cancer, the patient's overall health, and other factors. Treatment may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these approaches. The goal of treatment is to remove or destroy the cancer cells and prevent them from spreading to other parts of the body.

Mechlorethamine, also known as nitrogen mustard, is a chemotherapy drug that has been used for many years to treat various types of cancer, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, and multiple myeloma. It works by damaging the DNA of cancer cells, which prevents them from dividing and growing. Mechlorethamine is usually given intravenously or by injection into a muscle. It can cause a range of side effects, including nausea, vomiting, hair loss, skin irritation, and an increased risk of infection. It can also cause more serious side effects, such as damage to the lungs, kidneys, or liver, and an increased risk of developing other types of cancer. Mechlorethamine is often used in combination with other chemotherapy drugs to increase its effectiveness and reduce the risk of side effects. It is important to note that the use of chemotherapy drugs like mechlorethamine can have serious side effects, and patients should discuss the potential risks and benefits with their healthcare provider before starting treatment.

Uterine cervical neoplasms refer to abnormal growths or tumors that develop in the cervix, which is the lower part of the uterus that connects to the vagina. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Cervical neoplasms can be classified into different types based on their characteristics and degree of malignancy. The most common type of cervical neoplasm is cervical intraepithelial neoplasia (CIN), which is a precancerous condition that can progress to invasive cervical cancer if left untreated. Cervical cancer is a serious health concern worldwide, and it is the fourth most common cancer in women globally. However, with regular screening and appropriate treatment, the prognosis for cervical cancer is generally good when it is detected early.

Carcinoma is a type of cancer that originates in the epithelial cells, which are the cells that line the surfaces of organs and tissues in the body. Carcinomas can develop in any part of the body, but they are most common in the skin, lungs, breast, prostate, and colon. Carcinomas are classified based on the location and type of epithelial cells from which they originate. For example, a carcinoma that develops in the skin is called a skin carcinoma, while a carcinoma that develops in the lungs is called a lung carcinoma. Carcinomas can be further classified as either non-melanoma skin cancers (such as basal cell carcinoma and squamous cell carcinoma) or melanoma, which is a more aggressive type of skin cancer that can spread to other parts of the body. Treatment for carcinomas depends on the type and stage of the cancer, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, or immunotherapy.

Glioblastoma is a type of brain tumor that is classified as a grade IV astrocytoma, which means it is a highly aggressive and rapidly growing cancer. It is the most common and deadly type of primary brain tumor in adults, accounting for about 15% of all brain tumors. Glioblastoma typically arises from the supportive cells of the brain called astrocytes, but it can also develop from other types of brain cells. The tumor is characterized by its ability to infiltrate and spread into the surrounding brain tissue, making it difficult to remove completely through surgery. Symptoms of glioblastoma can vary depending on the location of the tumor in the brain, but common symptoms include headaches, seizures, nausea, vomiting, memory loss, and changes in personality or behavior. Treatment for glioblastoma typically involves a combination of surgery, radiation therapy, and chemotherapy. Despite these treatments, glioblastoma is generally considered to be incurable, with a median survival rate of about 15 months from diagnosis.

Bleomycin is a chemotherapy drug that is used to treat various types of cancer, including lung cancer, testicular cancer, and Hodgkin's lymphoma. It works by damaging the DNA of cancer cells, which prevents them from dividing and growing. Bleomycin is usually given intravenously or by injection into a muscle. It can also be given as a mist in the lungs for lung cancer. Bleomycin can cause side effects such as nausea, vomiting, hair loss, and damage to the lungs, heart, and kidneys. It is important to carefully follow the instructions of a healthcare provider when taking bleomycin.

Iridium radioisotopes are radioactive isotopes of the element iridium that are used in various medical applications. These isotopes are typically produced by bombarding iridium targets with high-energy particles, such as protons or neutrons, in a nuclear reactor or particle accelerator. One commonly used iridium radioisotope in medicine is iridium-192 (Ir-192), which has a half-life of approximately 74 days and emits low-energy gamma rays. Ir-192 is often used in radiation therapy to treat cancer, as it can be placed directly into or near a tumor to deliver a high dose of radiation to the cancer cells while minimizing damage to surrounding healthy tissue. Another iridium radioisotope used in medicine is iridium-191 (Ir-191), which has a half-life of approximately 27 hours and emits beta particles. Ir-191 has been used in research to study the metabolism of certain drugs and to develop new imaging agents for use in diagnostic procedures. Overall, iridium radioisotopes have a number of potential applications in medicine, including cancer treatment, drug research, and diagnostic imaging. However, they must be handled with care due to their radioactivity, and appropriate safety measures must be taken to minimize the risk of exposure to radiation.

Osteoradionecrosis is a condition that occurs when healthy bone tissue becomes damaged or dies as a result of radiation therapy. It is a complication that can occur in patients who have received radiation to the head and neck, spine, pelvis, or other areas of the body. The damage to the bone tissue can lead to infection, pain, and other complications, and it can be difficult to treat. Treatment options may include antibiotics, surgery, and other therapies, depending on the severity of the condition.

Esophageal neoplasms refer to abnormal growths or tumors that develop in the esophagus, which is the muscular tube that carries food from the throat to the stomach. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Benign esophageal neoplasms include polyps, which are small, non-cancerous growths that can develop on the lining of the esophagus. Other examples of benign neoplasms include leiomyomas, which are smooth muscle tumors, and lipomas, which are fatty tumors. Malignant esophageal neoplasms, on the other hand, are more serious and can be further classified into two main types: squamous cell carcinomas and adenocarcinomas. Squamous cell carcinomas develop in the squamous cells that line the esophagus, while adenocarcinomas develop in the glandular cells that line the lower part of the esophagus, near the stomach. Esophageal neoplasms can cause a range of symptoms, including difficulty swallowing, chest pain, weight loss, and difficulty breathing. Treatment options for esophageal neoplasms depend on the type, size, and location of the tumor, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Glioma is a type of brain tumor that arises from the glial cells, which are the supportive cells of the brain and spinal cord. Gliomas are the most common type of primary brain tumor, accounting for about 80% of all brain tumors. They can occur in any part of the brain, but are most commonly found in the frontal and temporal lobes. Gliomas are classified based on their degree of malignancy, with grades I to IV indicating increasing levels of aggressiveness. Grade I gliomas are slow-growing and have a better prognosis, while grade IV gliomas are highly aggressive and have a poor prognosis. Symptoms of gliomas can vary depending on the location and size of the tumor, but may include headaches, seizures, changes in vision or speech, difficulty with coordination or balance, and personality changes. Treatment options for gliomas may include surgery, radiation therapy, chemotherapy, and targeted therapy, depending on the type and stage of the tumor.

Lymphatic metastasis is a type of cancer spread that occurs when cancer cells from a primary tumor travel through the lymphatic system and spread to other parts of the body. The lymphatic system is a network of vessels and organs that helps to fight infection and remove waste products from the body. When cancer cells enter the lymphatic system, they can travel through the lymph nodes, which are small, bean-shaped structures that filter out harmful substances from the lymph fluid. If the cancer cells reach the lymph nodes, they can multiply and form new tumors, which can then spread to other parts of the body through the lymphatic system. Lymphatic metastasis is a common way for cancer to spread, and it can occur in many different types of cancer, including breast cancer, lung cancer, and colon cancer.

Thoracic neoplasms refer to tumors that develop in the chest region, specifically in the lungs, pleura, mediastinum, or other structures within the thorax. These tumors can be either benign or malignant, and they can arise from a variety of cell types, including epithelial cells, mesenchymal cells, and hematopoietic cells. Some common types of thoracic neoplasms include lung cancer, mesothelioma, thymoma, and germ cell tumors. These tumors can cause a range of symptoms, depending on their location and size, including coughing, shortness of breath, chest pain, and weight loss. Diagnosis of thoracic neoplasms typically involves a combination of imaging studies, such as chest X-rays, CT scans, and PET scans, as well as biopsy to confirm the presence of cancer cells. Treatment options for thoracic neoplasms depend on the type and stage of the tumor, and may include surgery, radiation therapy, chemotherapy, and targeted therapy.

Doxorubicin is an anthracycline chemotherapy drug that is used to treat a variety of cancers, including breast cancer, ovarian cancer, and leukemia. It works by interfering with the production of DNA and RNA, which are essential for the growth and division of cancer cells. Doxorubicin is usually administered intravenously, and its side effects can include nausea, vomiting, hair loss, and damage to the heart and kidneys. It is a powerful drug that can be effective against many types of cancer, but it can also have serious side effects, so it is typically used in combination with other treatments or in low doses.

Vinblastine is a chemotherapy drug that is used to treat various types of cancer, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, and breast cancer. It works by interfering with the formation of microtubules, which are essential components of the cell's cytoskeleton. This disruption of the cytoskeleton can cause the cancer cells to stop dividing and eventually die. Vinblastine is usually administered intravenously and can cause side effects such as nausea, vomiting, hair loss, and low blood cell counts.

Sarcoma is a type of cancer that arises from connective tissue, including bone, cartilage, fat, muscle, and other tissues. Sarcomas can occur in any part of the body, but they are most common in the arms, legs, trunk, and head and neck. Sarcomas are classified based on the type of tissue from which they arise and the specific characteristics of the cancer cells. There are more than 100 different types of sarcomas, and they can be further divided into two main categories: soft tissue sarcomas and bone sarcomas. Soft tissue sarcomas are cancers that develop in the soft tissues of the body, such as muscle, fat, and connective tissue. They can occur anywhere in the body, but they are most common in the arms, legs, and trunk. Bone sarcomas, on the other hand, are cancers that develop in the bones of the body. They are less common than soft tissue sarcomas and can occur in any bone, but they are most common in the long bones of the arms and legs. Sarcomas can be treated with a variety of approaches, including surgery, radiation therapy, chemotherapy, and targeted therapy. The specific treatment plan will depend on the type and stage of the cancer, as well as the patient's overall health and preferences.

Cyclophosphamide is an immunosuppressive drug that is commonly used to treat various types of cancer, including lymphoma, leukemia, and multiple myeloma. It works by inhibiting the growth and division of cells, including cancer cells, and by suppressing the immune system. Cyclophosphamide is usually administered intravenously or orally, and its dosage and duration of treatment depend on the type and stage of cancer being treated, as well as the patient's overall health. Side effects of cyclophosphamide can include nausea, vomiting, hair loss, fatigue, and an increased risk of infection. It can also cause damage to the kidneys, bladder, and reproductive organs, and may increase the risk of developing certain types of cancer later in life.

Androgen antagonists are a class of drugs that block the effects of androgens, which are male sex hormones such as testosterone. These drugs are often used to treat conditions such as prostate cancer, acne, and hirsutism (excessive hair growth in women) by reducing the levels of androgens in the body. They work by binding to androgen receptors, preventing androgens from binding to these receptors and exerting their effects. Examples of androgen antagonists include flutamide, bicalutamide, and spironolactone.

Oropharyngeal neoplasms refer to tumors that develop in the oropharynx, which is the part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the back of the throat. These tumors can be either benign or malignant, and they can arise from any of the tissues in the oropharynx. Malignant oropharyngeal neoplasms, also known as oropharyngeal cancers, are typically caused by exposure to certain risk factors, such as tobacco and alcohol use, human papillomavirus (HPV) infection, and a history of head and neck radiation therapy. These tumors can spread to other parts of the body, including the lymph nodes, lungs, and liver. The diagnosis of oropharyngeal neoplasms typically involves a combination of physical examination, imaging studies, and biopsy. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches, depending on the type and stage of the tumor, as well as the patient's overall health and preferences.

Supratentorial neoplasms are tumors that occur in the brain above the tentorium cerebelli, which is a membrane that separates the cerebrum from the cerebellum. The cerebrum is the largest part of the brain and is responsible for many of the body's higher functions, such as thinking, memory, and movement. Supratentorial neoplasms can be either benign (non-cancerous) or malignant (cancerous). They can also be primary, meaning they start in the brain, or secondary, meaning they have spread from another part of the body to the brain. Some common types of supratentorial neoplasms include gliomas (tumors that arise from glial cells, which support and protect neurons), meningiomas (tumors that arise from cells that line the brain and spinal cord), and pituitary adenomas (tumors that arise from the pituitary gland, which is located at the base of the brain). Treatment for supratentorial neoplasms depends on the type, size, location, and whether the tumor is benign or malignant. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Lomustine is a chemotherapy drug that is used to treat various types of cancer, including brain tumors, Hodgkin's lymphoma, and non-Hodgkin's lymphoma. It works by interfering with the growth and division of cancer cells, which can slow down or stop the growth of tumors. Lomustine is usually given orally, although it can also be administered intravenously or intramuscularly. It is a prodrug, meaning that it is converted into an active form in the body before it can be used to treat cancer. Common side effects of lomustine include nausea, vomiting, hair loss, fatigue, and an increased risk of infection.

Nimustine, also known as CCNU or carmustine, is a chemotherapy drug that is used to treat various types of cancer, including brain tumors, breast cancer, and lung cancer. It works by interfering with the growth and division of cancer cells, which can slow down or stop the growth of tumors. Nimustine is usually given intravenously or orally, and it can cause a range of side effects, including nausea, vomiting, hair loss, fatigue, and a decreased appetite. It can also cause more serious side effects, such as damage to the liver or kidneys, and an increased risk of infection. Nimustine is often used in combination with other chemotherapy drugs or radiation therapy to increase its effectiveness and reduce the risk of side effects. It is important to carefully follow the instructions of your healthcare provider when taking nimustine, as it can be toxic if not used properly.

Hypopharyngeal neoplasms refer to tumors that develop in the hypopharynx, which is the lower part of the throat located just above the larynx. The hypopharynx is responsible for swallowing and breathing, and it is lined with squamous cells, which can become cancerous and form squamous cell carcinomas. Other types of neoplasms that can occur in the hypopharynx include adenoid cystic carcinomas, mucoepidermoid carcinomas, and salivary gland tumors. Treatment for hypopharyngeal neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches, depending on the type and stage of the cancer.

Amifostine is a medication that is used to protect against the harmful effects of radiation therapy and chemotherapy. It works by neutralizing the toxic effects of these treatments on healthy cells in the body. Amifostine is typically given before radiation therapy or chemotherapy to help reduce the risk of side effects such as nausea, vomiting, and hair loss. It is also sometimes used to protect the eyes and salivary glands from the effects of radiation therapy. Amifostine is available as a tablet that is taken by mouth. It is usually given in a dose of 1500 mg, which is divided into two doses of 750 mg, taken 30 minutes before radiation therapy or chemotherapy.

Bone neoplasms are abnormal growths or tumors that develop in the bones. They can be either benign (non-cancerous) or malignant (cancerous). Benign bone neoplasms are usually slow-growing and do not spread to other parts of the body, while malignant bone neoplasms can be invasive and spread to other parts of the body through the bloodstream or lymphatic system. There are several types of bone neoplasms, including osteosarcoma, Ewing's sarcoma, chondrosarcoma, and multiple myeloma. These tumors can affect any bone in the body, but they are most commonly found in the long bones of the arms and legs, such as the femur and tibia. Symptoms of bone neoplasms may include pain, swelling, and tenderness in the affected bone, as well as bone fractures that do not heal properly. Diagnosis typically involves imaging tests such as X-rays, MRI scans, and CT scans, as well as a biopsy to examine a sample of the tumor tissue. Treatment for bone neoplasms depends on the type and stage of the tumor, as well as the patient's overall health. Options may include surgery to remove the tumor, radiation therapy to kill cancer cells, chemotherapy to shrink the tumor, and targeted therapy to block the growth of cancer cells. In some cases, a combination of these treatments may be used.

Prednisone is a synthetic corticosteroid medication that is used to treat a variety of medical conditions, including allergies, autoimmune disorders, inflammatory diseases, and certain types of cancer. It works by reducing inflammation and suppressing the immune system, which can help to reduce symptoms and slow the progression of the disease. Prednisone is available in both oral and injectable forms, and it is typically prescribed in doses that are gradually increased or decreased over time, depending on the patient's response to the medication and the specific condition being treated. While prednisone can be effective in treating a wide range of medical conditions, it can also have side effects, including weight gain, mood changes, and increased risk of infections. Therefore, it is important for patients to work closely with their healthcare provider to monitor their response to the medication and adjust the dosage as needed.

Neoplasm metastasis refers to the spread of cancer cells from a primary tumor to other parts of the body. This occurs when cancer cells break away from the primary tumor, enter the bloodstream or lymphatic system, and travel to distant organs or tissues, where they can form new tumors. Metastasis is a major cause of cancer-related deaths, as it makes the disease more difficult to treat and increases the risk of complications. The ability of cancer cells to metastasize is a key factor in determining the prognosis for patients with cancer.

Mucositis is a condition characterized by inflammation and damage to the mucous membranes lining the digestive tract, mouth, and throat. It can be caused by a variety of factors, including chemotherapy, radiation therapy, infection, autoimmune disorders, and certain medications. Symptoms of mucositis may include pain, swelling, redness, and difficulty swallowing or eating. In severe cases, it can lead to malnutrition, dehydration, and difficulty breathing. Treatment for mucositis may include pain management, nutritional support, and medications to reduce inflammation and promote healing.

Central Nervous System (CNS) neoplasms are tumors that develop in the brain or spinal cord. These tumors can be either benign (non-cancerous) or malignant (cancerous). CNS neoplasms can affect any part of the brain or spinal cord, including the brainstem, cerebellum, and spinal cord. The symptoms of CNS neoplasms can vary depending on the location and size of the tumor. Common symptoms include headaches, seizures, changes in vision or hearing, difficulty with balance or coordination, and changes in personality or behavior. Diagnosis of CNS neoplasms typically involves a combination of imaging tests, such as MRI or CT scans, and a biopsy to confirm the presence of a tumor. Treatment options for CNS neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. CNS neoplasms can be challenging to treat because they are often located in critical areas of the brain or spinal cord, and because they can be difficult to completely remove without causing damage to surrounding healthy tissue. However, with appropriate treatment and management, many people with CNS neoplasms are able to live long and fulfilling lives.

Skull base neoplasms refer to tumors that develop in the skull base region, which is the area where the skull and the base of the brain meet. The skull base is a complex and critical area of the body, containing vital structures such as the brainstem, cranial nerves, and blood vessels. Skull base neoplasms can be either benign or malignant and can arise from a variety of tissues, including bone, cartilage, nerves, and blood vessels. These tumors can cause a range of symptoms, depending on their location and size, including headache, hearing loss, facial weakness, and difficulty swallowing or speaking. Treatment options for skull base neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Nose neoplasms refer to tumors or abnormal growths that develop in the tissues of the nose. These neoplasms can be benign (non-cancerous) or malignant (cancerous). Benign nose neoplasms include nasal polyps, which are non-cancerous growths that develop in the lining of the nasal passages. Other examples of benign nose neoplasms include angiofibromas, which are benign tumors that develop in the blood vessels of the nose and sinuses, and basal cell carcinomas, which are non-cancerous skin growths that can occur on the nose. Malignant nose neoplasms, on the other hand, are cancerous tumors that can develop in any of the tissues of the nose, including the nasal cavity, sinuses, and nasal septum. Examples of malignant nose neoplasms include squamous cell carcinomas, which are the most common type of cancerous nose neoplasm, and adenocarcinomas, which are less common but can be more aggressive. Treatment for nose neoplasms depends on the type and stage of the tumor, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Early detection and treatment are important for improving outcomes and reducing the risk of complications.

Etoposide is a chemotherapy drug that is used to treat various types of cancer, including small cell lung cancer, ovarian cancer, testicular cancer, and some types of leukemia. It works by interfering with the process of cell division, which is necessary for cancer cells to grow and multiply. Etoposide is usually given intravenously or orally, and its side effects can include nausea, vomiting, hair loss, and an increased risk of infection.

Esthesioneuroblastoma, also known as olfactory neuroblastoma, is a rare and aggressive type of cancer that arises from the olfactory epithelium, which is the tissue that lines the upper part of the nasal cavity and is responsible for the sense of smell. This type of cancer typically affects adults in their 40s and 50s and is more common in men than in women. Esthesioneuroblastoma can spread to other parts of the body, including the brain and spinal cord, and is often difficult to treat. Treatment options for this type of cancer may include surgery, radiation therapy, and chemotherapy.

Vindesine is a chemotherapy medication that is used to treat certain types of cancer, including small cell lung cancer, Kaposi's sarcoma, and testicular cancer. It works by interfering with the growth and division of cancer cells, which can slow the growth of tumors and help control the spread of cancer. Vindesine is usually administered intravenously (through a vein) or as a slow injection under the skin. It can cause side effects such as nausea, vomiting, hair loss, and low blood cell counts.

Meningeal neoplasms refer to tumors that develop in the meninges, which are the protective membranes that surround the brain and spinal cord. These tumors can be either benign (non-cancerous) or malignant (cancerous). Meningeal neoplasms can occur in any part of the meninges, including the dura mater (outermost layer), arachnoid mater (middle layer), and pia mater (innermost layer). They can also occur in the leptomeninges, which are the delicate membranes that cover the brain and spinal cord. Symptoms of meningeal neoplasms can include headache, nausea, vomiting, double vision, weakness or numbness in the extremities, and changes in mental status. Diagnosis typically involves a combination of imaging studies, such as MRI or CT scans, and a biopsy to confirm the presence of a tumor. Treatment for meningeal neoplasms depends on the type, location, and size of the tumor, as well as the patient's overall health. Options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Carboplatin is a chemotherapy drug that is used to treat various types of cancer, including ovarian, lung, bladder, and testicular cancer. It works by interfering with the ability of cancer cells to make DNA, which is necessary for their growth and division. This leads to the death of cancer cells and slows the growth of tumors. Carboplatin is usually given intravenously (through a vein) and is often used in combination with other chemotherapy drugs. It can cause side effects such as nausea, vomiting, hair loss, and anemia.

Stomatitis is a medical term that refers to inflammation or irritation of the mouth, including the gums, tongue, lips, and inner lining of the cheeks. It can be caused by a variety of factors, including infections, allergies, irritants, medications, and certain diseases. Symptoms of stomatitis may include pain, swelling, redness, sores, and difficulty swallowing or speaking. Treatment for stomatitis depends on the underlying cause and may include medications, lifestyle changes, or other therapies.

Astrocytoma is a type of brain tumor that arises from astrocytes, which are star-shaped cells that support and nourish neurons in the brain. Astrocytomas are the most common type of primary brain tumor, accounting for about 30% of all brain tumors. They can occur at any age, but are most common in adults between the ages of 40 and 60. Astrocytomas are classified into four grades based on their degree of malignancy and ability to invade surrounding tissues. Grade I astrocytomas are slow-growing and low-grade, while grade IV astrocytomas are highly aggressive and fast-growing. Treatment options for astrocytomas depend on the grade of the tumor, the location of the tumor in the brain, and the patient's overall health. Treatment may include surgery, radiation therapy, chemotherapy, and targeted therapy.

Prostate-Specific Antigen (PSA) is a protein produced by the cells of the prostate gland in men. It is normally present in small amounts in the blood, but levels can increase if there is an abnormality in the prostate gland, such as cancer. PSA testing is commonly used as a screening tool for prostate cancer, as elevated levels of PSA can indicate the presence of cancerous cells in the prostate gland. However, it is important to note that not all cases of elevated PSA levels are due to cancer, and some men with prostate cancer may have normal PSA levels. Therefore, PSA testing should be interpreted in conjunction with other clinical information and diagnostic tests.

Testicular neoplasms refer to tumors or abnormal growths that develop in the testicles, which are the male reproductive organs responsible for producing sperm and testosterone. These neoplasms can be either benign (non-cancerous) or malignant (cancerous), and they can occur in either one or both testicles. Testicular neoplasms are relatively rare, but they are one of the most common types of cancer in young men between the ages of 15 and 35. The most common type of testicular cancer is germ cell tumors, which account for about 95% of all testicular cancers. Other types of testicular neoplasms include Leydig cell tumors, Sertoli cell tumors, and teratomas. Symptoms of testicular neoplasms may include a painless lump or swelling in the testicle, a feeling of heaviness or discomfort in the scrotum, or a change in the size or shape of the testicle. If left untreated, testicular cancer can spread to other parts of the body, including the lymph nodes, lungs, and liver. Diagnosis of testicular neoplasms typically involves a physical examination of the testicles, as well as imaging tests such as ultrasound or CT scans. A biopsy may also be performed to confirm the presence of cancer cells. Treatment for testicular neoplasms depends on the type and stage of the cancer. Options may include surgery to remove the affected testicle or part of the testicle, chemotherapy to kill cancer cells, or radiation therapy to shrink tumors. In some cases, watchful waiting may be recommended for small, slow-growing tumors that are not likely to cause harm.

Meningioma is a type of benign (non-cancerous) tumor that develops on the meninges, which are the protective membranes that surround the brain and spinal cord. Meningiomas are the most common type of primary brain tumor, accounting for about 30-40% of all brain tumors. Meningiomas can occur anywhere on the meninges, but they are most commonly found on the surface of the brain or along the base of the skull. They can also occur in the spinal canal, where they are called spinal meningiomas. Meningiomas are usually slow-growing and may not cause any symptoms for many years. However, as they grow, they can put pressure on surrounding brain tissue, causing symptoms such as headaches, seizures, vision problems, and changes in personality or behavior. Treatment for meningiomas depends on the size and location of the tumor, as well as the patient's overall health. Small meningiomas that are not causing symptoms may not require treatment and can be monitored with regular imaging studies. Larger tumors or those causing symptoms may be treated with surgery, radiation therapy, or a combination of both.

Soft tissue neoplasms are abnormal growths of cells that develop in the soft tissues of the body, such as the muscles, tendons, ligaments, fat, and blood vessels. These tumors can be benign (non-cancerous) or malignant (cancerous), and they can occur in any part of the body. Soft tissue neoplasms can be further classified based on their cell type, such as fibrous tumors, sarcomas, and leiomyomas. Some common examples of soft tissue neoplasms include lipomas (benign fatty tumors), leiomyomas (benign smooth muscle tumors), and sarcomas (malignant tumors that develop from connective tissue). The diagnosis of soft tissue neoplasms typically involves a combination of physical examination, imaging studies (such as MRI or CT scans), and biopsy (the removal of a small sample of tissue for examination under a microscope). Treatment options for soft tissue neoplasms depend on the type, size, location, and stage of the tumor, as well as the patient's overall health and preferences. They may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Carcinoma, Small Cell is a type of cancer that begins in the cells of the lungs. It is called "small cell" because the cancer cells are smaller than the normal cells in the lungs. Small cell carcinoma is a fast-growing cancer that spreads quickly to other parts of the body. It is usually treated with chemotherapy and radiation therapy, and in some cases, surgery. Small cell carcinoma is more common in men than in women and is often associated with smoking. It is a very aggressive form of cancer and can be difficult to treat.

Spinal cord neoplasms are tumors that develop in the spinal cord, which is a bundle of nerves that runs from the base of the brain down through the back. These tumors can be either benign (non-cancerous) or malignant (cancerous), and they can occur at any point along the length of the spinal cord. Spinal cord neoplasms can cause a variety of symptoms, depending on their location and size. Some common symptoms include back pain, weakness or numbness in the arms or legs, difficulty walking or standing, and changes in bladder or bowel function. In some cases, spinal cord neoplasms can also cause problems with sensation, coordination, and balance. Diagnosis of spinal cord neoplasms typically involves a combination of imaging tests, such as MRI or CT scans, and a physical examination by a healthcare provider. Treatment options for spinal cord neoplasms depend on the type and location of the tumor, as well as the patient's overall health and preferences. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Methotrexate is a medication that is used to treat a variety of medical conditions, including cancer, autoimmune diseases, and certain skin conditions. It is a chemotherapy drug that works by inhibiting the growth and division of cells, which can slow or stop the progression of cancer or other diseases. Methotrexate is usually given by injection or taken by mouth, and it can have a number of side effects, including nausea, vomiting, and hair loss. It is important to carefully follow the instructions of a healthcare provider when taking methotrexate, as it can be a potent medication that requires careful monitoring.

Abdominal neoplasms refer to tumors or growths that develop in the abdominal cavity, which includes the organs in the abdomen such as the liver, pancreas, stomach, small intestine, large intestine, and ovary. These neoplasms can be benign or malignant, and they can cause a variety of symptoms depending on their location and size. Some common symptoms of abdominal neoplasms include abdominal pain, bloating, nausea, vomiting, changes in bowel habits, weight loss, and fatigue. Treatment options for abdominal neoplasms depend on the type and stage of the tumor, as well as the overall health of the patient. They may include surgery, chemotherapy, radiation therapy, or a combination of these treatments.

An oligodendroglioma is a type of brain tumor that arises from the oligodendrocytes, which are cells that produce myelin, a fatty substance that insulates nerve fibers and allows them to transmit electrical signals more efficiently. Oligodendrogliomas are typically slow-growing tumors that can occur in both children and adults, although they are more common in adults. They are usually found in the white matter of the brain, which is the area responsible for coordinating and integrating the activity of different brain regions. Oligodendrogliomas can cause a variety of symptoms, depending on their location and size, including headaches, seizures, and changes in vision, speech, and movement. Treatment for oligodendrogliomas typically involves surgery to remove as much of the tumor as possible, followed by radiation therapy and/or chemotherapy to kill any remaining cancer cells.

In the medical field, recurrence refers to the reappearance of a disease or condition after it has been treated or has gone into remission. Recurrence can occur in various medical conditions, including cancer, infections, and autoimmune diseases. For example, in cancer, recurrence means that the cancer has come back after it has been treated with surgery, chemotherapy, radiation therapy, or other treatments. Recurrence can occur months, years, or even decades after the initial treatment. In infections, recurrence means that the infection has returned after it has been treated with antibiotics or other medications. Recurrence can occur due to incomplete treatment, antibiotic resistance, or other factors. In autoimmune diseases, recurrence means that the symptoms of the disease return after they have been controlled with medication. Recurrence can occur due to changes in the immune system or other factors. Overall, recurrence is a significant concern for patients and healthcare providers, as it can require additional treatment and can impact the patient's quality of life.

Lymphoma, Non-Hodgkin (NHL) is a type of cancer that affects the lymphatic system, which is a part of the immune system. NHL is characterized by the abnormal growth of lymphocytes, a type of white blood cell, in the lymph nodes, spleen, and other parts of the body. There are many different types of NHL, and they can vary in their symptoms, progression, and treatment options. Some common symptoms of NHL include swollen lymph nodes, fever, night sweats, weight loss, and fatigue. NHL is typically diagnosed through a combination of physical examination, blood tests, imaging studies, and a biopsy of the affected tissue. Treatment options for NHL may include chemotherapy, radiation therapy, targeted therapy, and stem cell transplantation, depending on the type and stage of the cancer. Overall, NHL is a serious condition that requires prompt diagnosis and treatment to improve outcomes and quality of life for patients.

Fluorodeoxyglucose F18 (FDG) is a radioactive tracer used in positron emission tomography (PET) scans. It is a glucose analog that is taken up by cells in the body, particularly those with high metabolic activity, such as cancer cells. The FDG is then injected into the patient's bloodstream and travels to the cells where it is taken up. The PET scanner detects the radiation emitted by the FDG and creates detailed images of the body's tissues and organs. FDG PET scans are commonly used to diagnose and stage cancer, as well as to monitor the effectiveness of treatment.

Deoxycytidine is a nucleoside that is a building block of DNA. It is composed of a deoxyribose sugar, a nitrogenous base (cytosine), and a phosphate group. Deoxycytidine is a key component of the nucleic acid chain that makes up DNA, and it plays a crucial role in the process of DNA replication. In the medical field, deoxycytidine is sometimes used as a medication to treat certain types of cancer, such as chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). It works by inhibiting the growth and division of cancer cells.

Spinal cord compression is a medical condition in which the spinal cord is compressed or squeezed, leading to damage or dysfunction of the spinal cord. This can occur due to a variety of factors, including injury, disease, or tumors. The spinal cord is a long, thin bundle of nerves that runs down the center of the spinal column, or spine. It is responsible for transmitting signals between the brain and the rest of the body, controlling movement, sensation, and other bodily functions. When the spinal cord is compressed, it can disrupt these signals and cause a range of symptoms, depending on the location and severity of the compression. Symptoms of spinal cord compression may include pain or discomfort in the back or neck, weakness or numbness in the arms or legs, difficulty walking or standing, loss of bladder or bowel control, and changes in sensation or reflexes. In severe cases, spinal cord compression can lead to paralysis or even death. Treatment for spinal cord compression depends on the underlying cause and the severity of the compression. In some cases, conservative treatments such as rest, physical therapy, or medication may be sufficient to relieve symptoms and prevent further damage. In more severe cases, surgery may be necessary to relieve pressure on the spinal cord and restore function.

Anus Neoplasms refer to abnormal growths or tumors that develop in or around the anus. These growths can be either benign or malignant, and they can occur in various parts of the anal canal, including the rectum, anal verge, and anal sphincter. Benign anal neoplasms are non-cancerous growths that do not spread to other parts of the body. Examples of benign anal neoplasms include hemorrhoids, anal polyps, and skin tags. Malignant anal neoplasms, on the other hand, are cancerous growths that can spread to other parts of the body if left untreated. The most common type of malignant anal neoplasm is anal cancer, which is usually caused by the human papillomavirus (HPV) infection. Symptoms of anal neoplasms may include rectal bleeding, pain or discomfort during bowel movements, itching or discharge from the anus, and a lump or mass in the anal area. Diagnosis of anal neoplasms typically involves a physical examination, biopsy, and imaging tests such as colonoscopy or MRI. Treatment for anal neoplasms depends on the type, size, and location of the growth, as well as the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Early detection and treatment of anal neoplasms are crucial for improving the chances of a successful outcome.

Disease progression refers to the worsening or progression of a disease over time. It is a natural course of events that occurs in many chronic illnesses, such as cancer, heart disease, and diabetes. Disease progression can be measured in various ways, such as changes in symptoms, physical examination findings, laboratory test results, or imaging studies. In some cases, disease progression can be slowed or stopped through medical treatment, such as medications, surgery, or radiation therapy. However, in other cases, disease progression may be inevitable, and the focus of treatment may shift from trying to cure the disease to managing symptoms and improving quality of life. Understanding disease progression is important for healthcare providers to develop effective treatment plans and to communicate with patients about their condition and prognosis. It can also help patients and their families make informed decisions about their care and treatment options.

Genital neoplasms, female refer to tumors or abnormal growths that develop in the female reproductive system, including the ovaries, uterus, cervix, vagina, and vulva. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and can present with a variety of symptoms, including abnormal vaginal bleeding, pain, and swelling. Treatment options for genital neoplasms depend on the type, size, and location of the tumor, as well as the patient's overall health and age. Early detection and treatment are important for improving outcomes and reducing the risk of complications.

Pharyngeal neoplasms refer to tumors or growths that develop in the pharynx, which is the back of the throat that extends from the nasal cavity to the esophagus. The pharynx is divided into three main sections: the nasopharynx, oropharynx, and laryngopharynx. Pharyngeal neoplasms can be either benign or malignant, and they can occur in any part of the pharynx. Some common types of pharyngeal neoplasms include squamous cell carcinoma, adenoid cystic carcinoma, and salivary gland tumors. Symptoms of pharyngeal neoplasms may include difficulty swallowing, hoarseness, a persistent sore throat, ear pain, and a lump or mass in the neck. Diagnosis typically involves a physical examination, imaging tests such as CT scans or MRIs, and a biopsy to examine the tissue. Treatment for pharyngeal neoplasms depends on the type, size, and location of the tumor, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Medulloblastoma is a type of cancer that originates in the cerebellum, which is the part of the brain responsible for balance, coordination, and movement. It is the most common type of brain cancer in children, accounting for about 15% of all childhood brain tumors. Medulloblastoma can occur in both children and adults, but it is more common in children. It is usually diagnosed in children between the ages of 3 and 9 years old. Medulloblastoma is a highly aggressive cancer that can spread quickly to other parts of the brain and spinal cord. Treatment typically involves surgery to remove as much of the tumor as possible, followed by chemotherapy and radiation therapy to kill any remaining cancer cells. The prognosis for medulloblastoma depends on several factors, including the age of the patient, the stage of the cancer at diagnosis, and the response to treatment. With appropriate treatment, many people with medulloblastoma can survive for many years or even be cured. However, the long-term effects of treatment, such as cognitive impairment and secondary cancers, can be significant.

Seminoma is a type of cancer that originates in the testicles and is caused by the abnormal growth of cells in the seminiferous tubules, which are responsible for producing sperm. Seminoma is the most common type of testicular cancer, accounting for about 40-50% of all cases. Seminoma typically presents as a painless lump in the testicle, which may be noticed by the patient or discovered during a routine physical examination. Other symptoms may include swelling in the scrotum, a feeling of heaviness in the testicle, or a dull ache in the lower abdomen or back. Seminoma is usually diagnosed through a combination of physical examination, blood tests, and imaging studies such as ultrasound or CT scans. Treatment options for seminoma include surgery to remove the affected testicle, chemotherapy, and radiation therapy. The prognosis for seminoma is generally very good, with a five-year survival rate of over 95% for patients with localized disease.

Brain stem neoplasms refer to tumors that develop in the brain stem, which is the part of the brain that connects the spinal cord to the rest of the brain. The brain stem is responsible for controlling vital functions such as breathing, heart rate, and blood pressure, and it also plays a role in regulating consciousness and movement. Brain stem neoplasms can be either benign (non-cancerous) or malignant (cancerous). Benign brain stem tumors are less common than malignant tumors, but they can still cause significant symptoms and complications. Malignant brain stem tumors are more aggressive and can spread to other parts of the brain and body. Symptoms of brain stem neoplasms can vary depending on the location and size of the tumor, but they may include headache, nausea, vomiting, dizziness, weakness or numbness in the face, arms, or legs, difficulty speaking or swallowing, and changes in vision or hearing. Diagnosis typically involves a combination of imaging tests such as MRI or CT scans, as well as a biopsy to confirm the presence of a tumor. Treatment for brain stem neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. The goal of treatment is to remove or shrink the tumor, relieve symptoms, and improve quality of life. However, because the brain stem is a critical part of the brain, treatment for these tumors can be complex and may carry risks and complications.

Cerebellar neoplasms, also known as cerebellar tumors, are abnormal growths of cells that develop in the cerebellum, which is the part of the brain responsible for controlling balance, coordination, and movement. These tumors can be either benign (non-cancerous) or malignant (cancerous) and can occur at any age, although they are more common in adults. Cerebellar neoplasms can cause a variety of symptoms, depending on their size and location. Some common symptoms include headache, nausea and vomiting, dizziness, unsteadiness, difficulty with coordination and balance, weakness or numbness in the limbs, and changes in speech or vision. Diagnosis of cerebellar neoplasms typically involves a combination of imaging tests, such as MRI or CT scans, and a biopsy to confirm the presence of cancer cells. Treatment options for cerebellar neoplasms depend on the type, size, and location of the tumor, as well as the patient's overall health and preferences. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Orbital neoplasms refer to tumors or growths that develop in the orbit, which is the bony socket that surrounds the eye. These neoplasms can be benign (non-cancerous) or malignant (cancerous) and can affect the muscles, nerves, fat, or other tissues in the orbit. Some common types of orbital neoplasms include: 1. Benign tumors: These include adenomas (tumors made up of glandular tissue), hemangiomas (tumors made up of blood vessels), and schwannomas (tumors made up of nerve tissue). 2. Malignant tumors: These include squamous cell carcinomas (cancers that start in the squamous cells of the skin), melanomas (cancers that start in the pigment-producing cells of the skin), and lymphomas (cancers that start in the lymphatic system). 3. Inflammatory conditions: These include orbital inflammation, which can cause swelling and pain in the orbit. Orbital neoplasms can cause a variety of symptoms, including double vision, eye pain, swelling around the eye, and changes in the shape or size of the eye. Treatment options for orbital neoplasms depend on the type and location of the tumor, as well as the patient's overall health. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Ependymoma is a type of brain tumor that arises from the ependymal cells, which line the ventricles of the brain and the central canal of the spinal cord. These tumors are typically slow-growing and can occur at any age, although they are most common in children and young adults. Ependymomas can be classified into different subtypes based on their location and the specific genetic mutations they exhibit. Treatment for ependymoma typically involves surgery to remove as much of the tumor as possible, followed by radiation therapy and/or chemotherapy to kill any remaining cancer cells. The prognosis for ependymoma depends on several factors, including the location and size of the tumor, the patient's age and overall health, and the response to treatment.

Rhabdomyosarcoma is a type of cancer that arises from the cells that form skeletal muscle. It is the most common soft tissue sarcoma in children and adolescents, and can occur in any part of the body, but is most commonly found in the head and neck, genitourinary system, and extremities. Rhabdomyosarcoma is a highly aggressive cancer, and treatment typically involves a combination of surgery, chemotherapy, and radiation therapy. Despite aggressive treatment, the prognosis for rhabdomyosarcoma varies depending on the location and stage of the cancer, as well as the age and overall health of the patient.

Choroid neoplasms are abnormal growths or tumors that develop in the choroid layer of the eye. The choroid is a layer of blood vessels and connective tissue that lies between the retina and the sclera, and it plays an important role in regulating blood flow to the retina and providing nutrients to the eye. Choroid neoplasms can be either benign (non-cancerous) or malignant (cancerous). Benign choroid neoplasms are usually slow-growing and do not spread to other parts of the body. Malignant choroid neoplasms, on the other hand, can grow quickly and spread to other parts of the body through the bloodstream or lymphatic system. Symptoms of choroid neoplasms may include vision loss, floaters (spots or specks that appear in the field of vision), and changes in the appearance of the eye (such as a bulge or swelling). Diagnosis typically involves a comprehensive eye exam, including imaging tests such as ultrasound or magnetic resonance imaging (MRI). Treatment for choroid neoplasms depends on the type, size, and location of the tumor, as well as the patient's overall health and preferences. Options may include observation, laser therapy, radiation therapy, or surgery. It is important to consult with an ophthalmologist or other healthcare provider for proper diagnosis and treatment.

Eye neoplasms refer to abnormal growths or tumors that develop in the eye or its surrounding tissues. These tumors can be benign (non-cancerous) or malignant (cancerous) and can affect any part of the eye, including the eyelids, conjunctiva, iris, ciliary body, choroid, and retina. Eye neoplasms can cause a variety of symptoms, depending on their location and size. Some common symptoms include changes in vision, eye pain or discomfort, redness or swelling of the eye, and the appearance of a growth or mass on the eye or eyelid. Diagnosis of eye neoplasms typically involves a comprehensive eye exam, including a visual acuity test, dilated eye exam, and imaging tests such as ultrasound, CT scan, or MRI. Treatment options for eye neoplasms depend on the type, size, and location of the tumor, as well as the patient's overall health and preferences. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Male urogenital diseases refer to medical conditions that affect the male reproductive and urinary systems. These systems include the testes, prostate gland, seminal vesicles, vas deferens, and urethra. Some common male urogenital diseases include: 1. Erectile dysfunction: A condition where a man is unable to achieve or maintain an erection sufficient for sexual activity. 2. Prostatitis: Inflammation of the prostate gland, which can cause pain, difficulty urinating, and other symptoms. 3. Benign prostatic hyperplasia (BPH): A non-cancerous enlargement of the prostate gland that can cause difficulty urinating and other symptoms. 4. Testicular cancer: A type of cancer that starts in the testicles. 5. Urinary tract infections (UTIs): Infections that can occur in any part of the urinary system, including the bladder, kidneys, ureters, and urethra. 6. Varicocele: A swelling of the veins in the scrotum that can cause pain and affect fertility. 7. Hydrocele: A swelling of the scrotum caused by fluid accumulation. 8. Epididymitis: Inflammation of the epididymis, a coiled tube that stores and carries sperm. These conditions can be caused by a variety of factors, including infections, genetics, hormonal imbalances, and lifestyle factors. Treatment for male urogenital diseases may include medications, surgery, or other interventions, depending on the specific condition and its severity.

In the medical field, "neoplasm invasiveness" refers to the ability of a cancerous tumor to invade and spread beyond its original site of origin. This can occur through the bloodstream or lymphatic system, or by direct extension into surrounding tissues. The degree of invasiveness of a neoplasm can be an important factor in determining the prognosis and treatment options for a patient. More invasive tumors are generally considered to be more aggressive and may be more difficult to treat. However, the specific characteristics of the tumor, such as its type, stage, and location, as well as the overall health of the patient, can also play a role in determining the prognosis. Invasive neoplasms may also be referred to as malignant tumors, as they have the potential to spread and cause harm to surrounding tissues and organs. Non-invasive neoplasms, on the other hand, are generally considered to be benign and are less likely to spread.

Pancreatic neoplasms refer to abnormal growths or tumors that develop in the pancreas, a gland located in the abdomen behind the stomach. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Pancreatic neoplasms can occur in various parts of the pancreas, including the exocrine gland (which produces digestive enzymes), the endocrine gland (which produces hormones), and the ducts (which carry digestive juices from the pancreas to the small intestine). Symptoms of pancreatic neoplasms can vary depending on the location and size of the tumor, but may include abdominal pain, weight loss, jaundice (yellowing of the skin and eyes), nausea, vomiting, and unexplained fatigue. Diagnosis of pancreatic neoplasms typically involves imaging tests such as CT scans, MRI scans, or ultrasound, as well as blood tests and biopsies. Treatment options may include surgery, chemotherapy, radiation therapy, or a combination of these approaches, depending on the type and stage of the neoplasm.

Leukopenia is a medical condition characterized by a low number of white blood cells (leukocytes) in the blood. The normal range of white blood cells in the blood is typically between 4,500 and 11,000 cells per microliter (µL) of blood. When the number of white blood cells falls below 4,000 cells/µL, it is considered leukopenia. Leukopenia can be caused by a variety of factors, including infections, autoimmune disorders, certain medications, radiation therapy, chemotherapy, and bone marrow disorders. It can also be a symptom of more serious underlying conditions, such as leukemia, lymphoma, or other blood disorders. Symptoms of leukopenia may include fatigue, weakness, fever, chills, and an increased susceptibility to infections. Treatment for leukopenia depends on the underlying cause and may include medications to stimulate the production of white blood cells, antibiotics to treat infections, or other therapies to address the underlying condition.

In the medical field, "Neoplasm, Residual" refers to a remaining or persistent tumor or mass after a surgical or other treatment intended to remove it. It is also known as a "recurrent tumor" or "metastatic tumor." Residual neoplasms can occur when the initial treatment was not completely effective in eliminating all cancer cells, or when cancer cells have spread to other parts of the body. Residual neoplasms may require additional treatment, such as radiation therapy or chemotherapy, to prevent the cancer from returning or spreading further.

Radiation injuries, experimental refer to injuries or damage caused to living tissue as a result of exposure to ionizing radiation in a laboratory or research setting. These injuries can occur intentionally, as part of a scientific study or experiment, or unintentionally, as a result of equipment malfunction or other accidents. The effects of radiation on living tissue can vary depending on the type and amount of radiation exposure, as well as the duration and frequency of exposure. Some common effects of radiation exposure include burns, skin damage, hair loss, nausea, vomiting, and fatigue. In severe cases, radiation exposure can lead to organ damage, tissue necrosis, and even death. Experimental radiation injuries are typically studied in order to better understand the effects of radiation on living tissue and to develop new treatments for radiation-related injuries and illnesses. These studies may involve exposing animals or cells to different types and doses of radiation, and then observing the effects of the radiation on the exposed organisms or cells. The results of these studies can be used to inform the development of new radiation protection measures and treatments for radiation-related injuries and illnesses in humans.

Ifosfamide is a chemotherapy drug that is used to treat various types of cancer, including ovarian cancer, testicular cancer, and sarcomas. It works by interfering with the production of DNA in cancer cells, which prevents them from dividing and growing. Ifosfamide is usually given intravenously, and it can also be given orally in some cases. It is often used in combination with other chemotherapy drugs to increase its effectiveness. Side effects of ifosfamide can include nausea, vomiting, hair loss, and an increased risk of infection.

Deglutition disorders refer to difficulties or problems with swallowing. This can include difficulty starting or stopping the swallowing process, difficulty swallowing solid or liquid foods, or difficulty feeling full after eating. Deglutition disorders can be caused by a variety of factors, including neurological disorders, structural abnormalities of the esophagus or mouth, and certain medications. Treatment for deglutition disorders depends on the underlying cause and may include medications, dietary changes, physical therapy, or surgery.

Eyelid neoplasms refer to abnormal growths or tumors that develop on the eyelid. These growths can be benign (non-cancerous) or malignant (cancerous). Some common types of eyelid neoplasms include basal cell carcinoma, squamous cell carcinoma, sebaceous gland carcinoma, and melanoma. Symptoms of eyelid neoplasms may include a lump or bump on the eyelid, changes in the shape or color of the eyelid, redness or swelling, and difficulty opening or closing the eye. Treatment for eyelid neoplasms may include surgery, radiation therapy, or chemotherapy, depending on the type and stage of the tumor. Early detection and treatment are important for improving the chances of a successful outcome.

Pituitary neoplasms are tumors that develop in the pituitary gland, a small endocrine gland located at the base of the brain. The pituitary gland is responsible for producing and regulating various hormones in the body, and when a tumor develops, it can disrupt the normal functioning of the gland and lead to a variety of symptoms. There are several types of pituitary neoplasms, including: 1. Pituitary adenomas: These are the most common type of pituitary neoplasm and are usually benign (non-cancerous). They can produce excessive amounts of hormones, leading to symptoms such as headaches, vision problems, and hormonal imbalances. 2. Pituitary carcinomas: These are rare and aggressive forms of pituitary neoplasms that can spread to other parts of the body. 3. Pituitary macroadenomas: These are larger tumors that can cause symptoms such as hormonal imbalances, headaches, and vision problems. 4. Pituitary microadenomas: These are smaller tumors that may not cause any symptoms, but can still be detected through imaging tests. Treatment for pituitary neoplasms may include surgery, radiation therapy, and medication to manage symptoms and hormone levels. The specific treatment approach will depend on the type and size of the tumor, as well as the patient's overall health and symptoms.

Mouth neoplasms refer to abnormal growths or tumors that develop in the mouth, including the lips, tongue, gums, palate, and throat. These growths can be benign (non-cancerous) or malignant (cancerous), and they can occur in any part of the mouth. Mouth neoplasms can be further classified based on their type, including: 1. Squamous cell carcinoma: This is the most common type of mouth cancer and usually develops on the lips, tongue, or floor of the mouth. 2. Adenoid cystic carcinoma: This type of cancer usually develops in the salivary glands and can spread to other parts of the mouth and neck. 3. Mucoepidermoid carcinoma: This is a rare type of cancer that develops in the salivary glands and can spread to other parts of the mouth and neck. 4. Basal cell carcinoma: This type of cancer usually develops on the lips and can spread to other parts of the mouth and neck. 5. Melanoma: This is a type of cancer that develops in the melanocytes (pigment-producing cells) of the mouth. Mouth neoplasms can cause a variety of symptoms, including pain, difficulty swallowing, changes in the appearance of the mouth, and bleeding. Treatment options for mouth neoplasms depend on the type, size, and location of the tumor, as well as the overall health of the patient. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Carcinoma, Adenoid Cystic is a type of cancer that originates in the salivary glands, particularly the minor salivary glands located in the mouth, nose, and throat. It is a slow-growing cancer that can spread to nearby tissues and organs, as well as to distant parts of the body through the bloodstream or lymphatic system. The adenoid cystic carcinoma cells are characterized by their ability to invade surrounding tissues and form cysts or nodules. These tumors can be difficult to diagnose and treat because they often do not cause symptoms until they have spread to other parts of the body. Treatment options for adenoid cystic carcinoma may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. The prognosis for this type of cancer depends on several factors, including the stage of the cancer at diagnosis, the location of the tumor, and the patient's overall health.

Hemangiopericytoma is a rare type of tumor that arises from the pericytes, which are cells that surround blood vessels. These tumors can occur in various parts of the body, including the brain, spinal cord, and other organs. Hemangiopericytomas are classified as intermediate-grade tumors, meaning they have a moderate potential for growth and spread. They can grow slowly or rapidly and may cause symptoms such as headaches, seizures, or neurological problems depending on their location. Treatment for hemangiopericytomas typically involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to prevent recurrence. The prognosis for hemangiopericytomas varies depending on the location and size of the tumor, as well as the patient's overall health.

Lymphoma is a type of cancer that affects the lymphatic system, which is a part of the immune system. It occurs when lymphocytes, a type of white blood cell, grow and divide uncontrollably, forming abnormal masses or tumors in the lymph nodes, spleen, bone marrow, or other parts of the body. There are two main types of lymphoma: Hodgkin lymphoma and non-Hodgkin lymphoma. Hodgkin lymphoma is a less common type of lymphoma that typically affects younger adults and has a better prognosis than non-Hodgkin lymphoma. Non-Hodgkin lymphoma is a more common type of lymphoma that can affect people of all ages and has a wide range of outcomes depending on the specific subtype and the stage of the disease. Symptoms of lymphoma can include swollen lymph nodes, fever, night sweats, weight loss, fatigue, and itching. Diagnosis typically involves a combination of physical examination, blood tests, imaging studies, and a biopsy of the affected tissue. Treatment for lymphoma depends on the subtype, stage, and overall health of the patient. It may include chemotherapy, radiation therapy, targeted therapy, immunotherapy, or a combination of these approaches. In some cases, a stem cell transplant may also be necessary.

Esophagitis is a medical condition characterized by the inflammation of the esophagus, which is the muscular tube that connects the throat to the stomach. The inflammation can be caused by a variety of factors, including acid reflux, infections, autoimmune disorders, and certain medications. Symptoms of esophagitis may include difficulty swallowing, chest pain, heartburn, regurgitation of food or stomach acid, and a sore throat. In severe cases, esophagitis can lead to complications such as bleeding, strictures (narrowing of the esophagus), and Barrett's esophagus (a condition in which the lining of the esophagus changes to resemble the lining of the stomach). Treatment for esophagitis depends on the underlying cause. In cases caused by acid reflux, lifestyle changes such as avoiding trigger foods and sleeping with the head of the bed elevated may be recommended. Medications such as proton pump inhibitors (PPIs) or histamine H2 blockers may also be prescribed to reduce acid production. In cases caused by infections, antibiotics may be necessary. In severe cases, surgery may be required to remove damaged tissue or repair strictures.

Chordoma is a rare type of cancer that arises from the remnants of the notochord, which is a structure that forms during fetal development and eventually disappears. Chordomas typically occur in the base of the skull or the spine, and they can grow slowly and infiltrate surrounding tissues, making them difficult to treat. Chordomas are classified as chordoid sarcomas, which are a type of sarcoma that arises from connective tissue. They are typically slow-growing tumors, but they can still be aggressive and cause significant morbidity and mortality if left untreated. The diagnosis of chordoma is usually made through a combination of imaging studies, such as MRI or CT scans, and biopsy of the tumor. Treatment options for chordoma include surgery, radiation therapy, and chemotherapy, and the choice of treatment depends on the location and size of the tumor, as well as the patient's overall health and preferences.

Paranasal sinus neoplasms refer to tumors that develop in the paranasal sinuses, which are air-filled cavities located within the skull. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) in nature. The paranasal sinuses include the frontal sinus, maxillary sinus, ethmoid sinus, and sphenoid sinus. Tumors can develop in any of these sinuses and can cause a range of symptoms, including facial pain, nasal congestion, headache, and facial swelling. Diagnosis of paranasal sinus neoplasms typically involves a combination of imaging studies, such as CT scans or MRI scans, and biopsy of the affected tissue. Treatment options depend on the type and stage of the tumor, as well as the patient's overall health. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Liver neoplasms refer to abnormal growths or tumors that develop in the liver. These growths can be either benign (non-cancerous) or malignant (cancerous). Benign liver neoplasms include hemangiomas, focal nodular hyperplasia, and adenomas. These growths are usually slow-growing and do not spread to other parts of the body. Malignant liver neoplasms, on the other hand, are more serious and include primary liver cancer (such as hepatocellular carcinoma) and secondary liver cancer (such as metastatic cancer from other parts of the body). These tumors can grow quickly and spread to other parts of the body, leading to serious health complications. Diagnosis of liver neoplasms typically involves imaging tests such as ultrasound, CT scan, or MRI, as well as blood tests and biopsy. Treatment options depend on the type and stage of the neoplasm, and may include surgery, chemotherapy, radiation therapy, or targeted therapy.

Thymus neoplasms refer to tumors that develop in the thymus gland, which is a small organ located in the upper chest, behind the breastbone. The thymus gland is responsible for the development and maturation of T-cells, which are a type of white blood cell that plays a critical role in the immune system. Thymus neoplasms can be either benign or malignant. Benign thymus neoplasms are non-cancerous and do not spread to other parts of the body. Malignant thymus neoplasms, on the other hand, are cancerous and can spread to other parts of the body, leading to serious health problems. Thymus neoplasms can be further classified based on their type, including thymoma, thymic carcinoma, and thymic hyperplasia. Thymoma is the most common type of thymus neoplasm, accounting for about 90% of all cases. Thymic carcinoma is a rare and aggressive type of thymus neoplasm, while thymic hyperplasia is a non-cancerous condition characterized by an overgrowth of thymus tissue. Thymus neoplasms can cause a variety of symptoms, including chest pain, difficulty breathing, coughing, and fatigue. Diagnosis typically involves imaging tests such as CT scans or MRI, as well as a biopsy to confirm the presence of a tumor. Treatment options for thymus neoplasms depend on the type and stage of the tumor, and may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

In the medical field, fatigue is a common symptom that can be caused by a variety of factors, including physical or mental exertion, lack of sleep, chronic illness, or medication side effects. Fatigue is characterized by a persistent feeling of tiredness or exhaustion that is not relieved by rest or sleep. Fatigue can be a symptom of many different medical conditions, including anemia, chronic fatigue syndrome, fibromyalgia, heart disease, sleep disorders, and thyroid disorders. It can also be a side effect of certain medications, such as antidepressants or chemotherapy drugs. In some cases, fatigue may be a sign of a more serious underlying condition, such as cancer or a neurological disorder. It is important to discuss any persistent feelings of fatigue with a healthcare provider to determine the cause and appropriate treatment.

Tonsillar neoplasms refer to abnormal growths or tumors that develop in the tonsils, which are two masses of lymphoid tissue located at the back of the throat. These neoplasms can be either benign (non-cancerous) or malignant (cancerous), and they can occur in both children and adults. Tonsillar neoplasms can present with a variety of symptoms, including difficulty swallowing, sore throat, ear pain, hoarseness, and difficulty breathing. In some cases, a tonsillar neoplasm may not cause any symptoms until it becomes large enough to cause blockage of the airway. Diagnosis of a tonsillar neoplasm typically involves a physical examination of the throat, followed by imaging studies such as a CT scan or MRI. A biopsy may also be performed to confirm the diagnosis and determine whether the neoplasm is benign or malignant. Treatment for tonsillar neoplasms depends on the type and stage of the tumor, as well as the patient's overall health. Benign tumors may be treated with surgery to remove the affected tonsil, while malignant tumors may require more extensive surgery, radiation therapy, or chemotherapy. In some cases, a combination of these treatments may be necessary.

Maxillary Sinus Neoplasms refer to tumors or abnormal growths that occur in the maxillary sinus, which is one of the four paired air-filled cavities located in the skull. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) in nature. The maxillary sinus is located in the cheekbone and is responsible for draining mucus and air from the nose. When a neoplasm develops in the maxillary sinus, it can cause a range of symptoms, including facial pain, swelling, congestion, and difficulty breathing. Diagnosis of maxillary sinus neoplasms typically involves a combination of imaging tests, such as CT scans or MRIs, and a biopsy to confirm the presence of cancer cells. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches, depending on the type and stage of the neoplasm.

Carcinoma, Adenosquamous is a type of cancer that arises from the cells that line the inside of certain organs, such as the lungs, bladder, and pancreas. These cells are called glandular cells, and they produce mucus or other substances that help to lubricate and protect the organs. Adenosquamous carcinoma is a rare type of cancer that arises when glandular cells and squamous cells, which are flat, scale-like cells that line the surface of organs, mix together and form a tumor. This type of cancer is often aggressive and can spread quickly to other parts of the body. Treatment for adenosquamous carcinoma typically involves surgery, radiation therapy, and chemotherapy.

Carcinoma, ductal, breast is a type of cancer that starts in the milk ducts of the breast. It is the most common type of breast cancer, accounting for about 80% of all breast cancer cases. Ductal carcinoma in situ (DCIS) is a non-invasive form of this cancer, where cancer cells are found in the lining of the milk ducts but have not spread to nearby tissues or lymph nodes. Invasive ductal carcinoma (IDC) is a more advanced form of the cancer, where cancer cells have invaded the surrounding breast tissue. The diagnosis of ductal carcinoma is usually made through a combination of a physical examination, imaging tests such as mammography or ultrasound, and a biopsy to confirm the presence of cancer cells. Treatment options for ductal carcinoma may include surgery, radiation therapy, chemotherapy, hormone therapy, or a combination of these approaches, depending on the stage and severity of the cancer.

Multiple primary neoplasms, also known as synchronous or metachronous neoplasms, are two or more neoplasms (cancerous or non-cancerous tumors) that occur in the same individual at the same time or at different times. In the medical field, multiple primary neoplasms can occur in different organs or tissues of the body, and they can be either cancerous (malignant) or non-cancerous (benign). The occurrence of multiple primary neoplasms can be due to various factors, including genetic predisposition, exposure to environmental toxins, lifestyle factors such as smoking and alcohol consumption, and certain medical conditions such as immunosuppression. The diagnosis of multiple primary neoplasms typically involves a thorough medical history, physical examination, imaging studies, and biopsy of the tumors. Treatment options depend on the type, location, and stage of the neoplasms, as well as the overall health of the individual.

Mediastinal neoplasms refer to tumors or masses that develop in the mediastinum, which is the central compartment of the chest that contains the heart, great vessels, esophagus, trachea, and thymus gland. These neoplasms can be benign or malignant and can arise from any tissue in the mediastinum, including lymph nodes, thymus, thyroid gland, and chest wall. Symptoms of mediastinal neoplasms may include difficulty breathing, chest pain, cough, hoarseness, and weight loss. Diagnosis typically involves imaging studies such as CT scans or MRI, and biopsy may be necessary to confirm the diagnosis and determine the type of neoplasm. Treatment options depend on the type and location of the neoplasm, and may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Pinealoma is a rare type of brain tumor that arises from the pineal gland, which is a small gland located in the center of the brain. The pineal gland is responsible for producing and regulating various hormones, including melatonin, which plays a role in regulating sleep and wakefulness. Pinealomas are typically slow-growing tumors that can cause a variety of symptoms, including headaches, vision problems, hormonal imbalances, and changes in behavior or personality. In some cases, pinealomas may not cause any noticeable symptoms until they have grown quite large. Diagnosis of a pinealoma typically involves a combination of imaging tests, such as MRI or CT scans, and a biopsy to confirm the presence of cancer cells. Treatment options for pinealomas may include surgery, radiation therapy, and chemotherapy, depending on the size and location of the tumor, as well as the patient's overall health and preferences.

Hemangiosarcoma is a rare and aggressive type of cancer that affects the blood vessels. It is a malignant tumor that arises from the endothelial cells lining the blood vessels. Hemangiosarcoma can occur in various parts of the body, including the liver, spleen, heart, and lungs, as well as other organs such as the skin, bones, and lymph nodes. In the liver, hemangiosarcoma is the most common type of primary liver cancer in dogs, but it can also occur in humans. It is usually found in older dogs and is more common in certain breeds, such as Boxers, Doberman Pinschers, and Great Danes. The symptoms of hemangiosarcoma can vary depending on the location of the tumor and the stage of the disease. Common symptoms include abdominal pain, weight loss, anemia, and a rapid heartbeat. In some cases, the tumor may rupture, causing internal bleeding and severe symptoms. Hemangiosarcoma is usually diagnosed through imaging tests such as ultrasound, CT scan, or MRI, and confirmed through a biopsy. Treatment options for hemangiosarcoma include surgery, chemotherapy, and radiation therapy. However, the prognosis for this type of cancer is generally poor, with a median survival time of only a few months.

Proctitis is an inflammation of the rectum, which is the final part of the large intestine. It can be caused by a variety of factors, including infections, injuries, autoimmune disorders, and certain medications. Symptoms of proctitis may include rectal pain, bleeding, itching, discharge, and difficulty passing stool. Treatment for proctitis depends on the underlying cause and may include medications, lifestyle changes, and in some cases, surgery.

Iodine radioisotopes are radioactive forms of the element iodine that are used in medical imaging and treatment procedures. These isotopes have a nucleus that contains an odd number of neutrons, which makes them unstable and causes them to emit radiation as they decay back to a more stable form of iodine. There are several different iodine radioisotopes that are commonly used in medical applications, including iodine-123, iodine-125, and iodine-131. Each of these isotopes has a different half-life, which is the amount of time it takes for half of the radioactive material to decay. The half-life of an iodine radioisotope determines how long it will remain in the body and how much radiation will be emitted during that time. Iodine radioisotopes are often used in diagnostic imaging procedures, such as thyroid scans, to help doctors visualize the structure and function of the thyroid gland. They may also be used in therapeutic procedures, such as radiation therapy, to treat thyroid cancer or other thyroid disorders. In these cases, the radioactive iodine is administered to the patient and selectively absorbed by the thyroid gland, where it emits radiation that damages or destroys cancerous cells.

Mitomycin is a chemotherapy drug that is used to treat various types of cancer, including bladder cancer, head and neck cancer, and sarcoma. It works by interfering with the DNA replication process in cancer cells, which prevents them from dividing and growing. Mitomycin is usually given as an intravenous injection or as a solution that is applied directly to the tumor. It can cause side effects such as nausea, vomiting, diarrhea, and mouth sores.

Small cell lung carcinoma (SCLC) is a type of lung cancer that begins in the cells that line the airways and alveoli (tiny air sacs) in the lungs. It is called "small cell" because the cancer cells are small and round, and they grow quickly and aggressively. SCLC is a highly aggressive form of lung cancer that tends to spread quickly to other parts of the body, such as the brain, liver, and bones. It is usually diagnosed at an advanced stage, which makes it more difficult to treat. Treatment for SCLC typically involves a combination of chemotherapy and radiation therapy. In some cases, surgery may also be an option. The goal of treatment is to shrink the tumor and control the cancer's growth, as well as to relieve symptoms and improve the patient's quality of life. SCLC is more common in men than in women, and it is more common in smokers than in non-smokers. However, it can occur in non-smokers as well. The prognosis for SCLC is generally poor, with a five-year survival rate of less than 5%.

Retinoblastoma is a rare type of cancer that develops in the retina of the eye, which is the light-sensitive tissue at the back of the eye. It is most commonly found in children, but can also occur in adults. Retinoblastoma is a highly aggressive cancer that can spread quickly to other parts of the body if not treated promptly. Treatment options for retinoblastoma include surgery, chemotherapy, radiation therapy, and laser therapy. Early detection and treatment are crucial for a good prognosis.

Misonidazole is a chemotherapy drug that is used to treat certain types of cancer, particularly those that are resistant to other treatments. It works by interfering with the DNA replication of cancer cells, which can cause them to die. Misonidazole is typically administered in combination with other chemotherapy drugs and is usually given intravenously. It is also sometimes used in combination with radiation therapy. Misonidazole can cause side effects such as nausea, vomiting, and fatigue, and it may also increase the risk of developing certain types of cancer.

Pleural neoplasms refer to tumors that develop in the pleura, which is the thin layer of tissue that covers the lungs and lines the inside of the chest cavity. These tumors can be either benign (non-cancerous) or malignant (cancerous). There are two types of pleural neoplasms: primary pleural neoplasms and secondary pleural neoplasms. Primary pleural neoplasms are tumors that start in the pleura itself, while secondary pleural neoplasms are tumors that have spread to the pleura from another part of the body. Some common types of pleural neoplasms include mesothelioma, a type of cancer that is often associated with exposure to asbestos, and pleural effusion, which is the accumulation of fluid in the pleural space. Other types of pleural neoplasms include pleural fibroma, pleural sarcoma, and pleural mesothelioma. The diagnosis of pleural neoplasms typically involves a combination of imaging tests, such as chest X-rays, CT scans, and MRI scans, as well as a biopsy to confirm the presence of cancer cells. Treatment options for pleural neoplasms depend on the type and stage of the cancer, as well as the overall health of the patient.

Vaginal neoplasms refer to abnormal growths or tumors that develop in the vaginal tissue. These growths can be benign (non-cancerous) or malignant (cancerous). Vaginal neoplasms can occur in any part of the vagina, including the vestibule, the cervix, the corpus, and the vagina itself. Some common types of vaginal neoplasms include vaginal polyps, vaginal cysts, vaginal leiomyomas (fibroids), vaginal adenosis (abnormal growth of glandular tissue), vaginal intraepithelial neoplasia (VIN), and vaginal cancer. VIN is a precancerous condition that can progress to invasive vaginal cancer if left untreated. Vaginal cancer is a rare but serious condition that can be treated with surgery, radiation therapy, chemotherapy, or a combination of these treatments. It is important for women to be aware of the signs and symptoms of vaginal neoplasms, such as abnormal vaginal bleeding, pain during intercourse, and changes in vaginal discharge, and to seek medical attention if they experience any of these symptoms. Early detection and treatment of vaginal neoplasms can improve outcomes and increase the chances of successful treatment.

Skin neoplasms refer to abnormal growths or tumors that develop on the skin. These growths can be benign (non-cancerous) or malignant (cancerous). Skin neoplasms can occur anywhere on the body and can vary in size, shape, and color. Some common types of skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and keratosis. These growths can be treated with a variety of methods, including surgery, radiation therapy, chemotherapy, and immunotherapy. It is important to have any unusual skin growths evaluated by a healthcare professional to determine the best course of treatment.

Leukemia, radiation-induced is a type of cancer that develops in the blood-forming cells of the bone marrow as a result of exposure to ionizing radiation. Ionizing radiation is a type of energy that has enough force to remove tightly bound electrons from atoms, causing them to become ionized. This type of radiation is commonly used in medical treatments such as radiation therapy for cancer, but it can also be caused by exposure to nuclear accidents, nuclear weapons, and certain types of medical imaging procedures. Radiation-induced leukemia typically develops several years after exposure to radiation, and the risk of developing the disease increases with the dose and duration of exposure. The most common type of radiation-induced leukemia is chronic lymphocytic leukemia (CLL), which is a type of cancer that affects the white blood cells called lymphocytes. Other types of radiation-induced leukemia include acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL). Treatment for radiation-induced leukemia typically involves chemotherapy, which uses drugs to kill cancer cells, and sometimes radiation therapy to target the cancer cells. In some cases, a stem cell transplant may be necessary to replace the damaged bone marrow with healthy cells. The prognosis for radiation-induced leukemia depends on several factors, including the type and stage of the cancer, the patient's overall health, and the response to treatment.

Paclitaxel is a chemotherapy drug that is used to treat various types of cancer, including ovarian, breast, lung, and pancreatic cancer. It works by interfering with the normal functioning of the microtubules, which are structures in the cell that help it divide and grow. By disrupting the microtubules, paclitaxel can slow or stop the growth of cancer cells. It is usually administered intravenously, either alone or in combination with other chemotherapy drugs.

Optic nerve neoplasms refer to tumors or growths that develop on or near the optic nerve, which is responsible for transmitting visual information from the eye to the brain. These neoplasms can be either benign or malignant and can cause a variety of symptoms, including vision loss, eye pain, and changes in visual field. Treatment options for optic nerve neoplasms depend on the type and location of the tumor, as well as the patient's overall health and the severity of their symptoms. Some common treatments for optic nerve neoplasms include surgery, radiation therapy, and chemotherapy.

Urogenital neoplasms refer to tumors or abnormal growths that develop in the urinary and genital systems of the body. These neoplasms can occur in various parts of the urinary system, including the kidneys, ureters, bladder, and urethra, as well as in the genital system, including the prostate, testicles, ovaries, and uterus. Urogenital neoplasms can be either benign or malignant. Benign neoplasms are non-cancerous and do not spread to other parts of the body, while malignant neoplasms, also known as cancers, are cancerous and can invade nearby tissues and spread to other parts of the body through the bloodstream or lymphatic system. Some common types of urogenital neoplasms include kidney cancer, bladder cancer, prostate cancer, testicular cancer, ovarian cancer, and uterine cancer. The symptoms of urogenital neoplasms can vary depending on the location and type of the tumor, but may include pain, blood in the urine or stool, difficulty urinating, and changes in bowel or bladder habits. Treatment options for urogenital neoplasms may include surgery, radiation therapy, chemotherapy, and targeted therapy, depending on the stage and type of the tumor.

Urinary bladder neoplasms refer to abnormal growths or tumors that develop in the urinary bladder. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Benign neoplasms include cysts, polyps, and adenomas, while malignant neoplasms are classified as urothelial carcinomas, which are the most common type of bladder cancer. Symptoms of urinary bladder neoplasms may include blood in the urine, frequent urination, pain or burning during urination, and abdominal pain or discomfort. Diagnosis typically involves a combination of physical examination, imaging studies, and biopsy. Treatment options depend on the type, size, and stage of the neoplasm, and may include surgery, chemotherapy, radiation therapy, or a combination of these approaches.

Thymoma is a rare type of cancer that originates in the thymus gland, which is located in the upper chest behind the breastbone. The thymus gland is responsible for the development and maturation of T-cells, which are a type of white blood cell that plays a critical role in the immune system. Thymoma can develop in people of any age, but it is most common in adults between the ages of 40 and 60. The symptoms of thymoma can vary depending on the size and location of the tumor, but they may include chest pain, difficulty breathing, coughing, hoarseness, and swelling of the neck or face. Thymoma is typically diagnosed through a combination of imaging tests, such as CT scans or MRI scans, and a biopsy of the tumor. Treatment options for thymoma may include surgery to remove the tumor, radiation therapy, chemotherapy, or a combination of these approaches. The prognosis for thymoma depends on several factors, including the size and location of the tumor, the stage of the cancer, and the overall health of the patient.

Trismus is a medical condition characterized by difficulty in opening the mouth or jaw. It can be caused by a variety of factors, including injury to the jaw or muscles of the mouth, infection or inflammation of the jaw or teeth, or certain medical conditions such as stroke or multiple sclerosis. Trismus can make it difficult to eat, drink, or speak, and may require medical intervention to treat. Treatment options may include medications, physical therapy, or surgery, depending on the underlying cause of the trismus.

Melanoma is a type of skin cancer that begins in the cells that produce the pigment melanin. It is the most dangerous type of skin cancer, as it has the potential to spread to other parts of the body and be difficult to treat. Melanoma can occur in any part of the body, but it most commonly appears on the skin as a new mole or a change in an existing mole. Other signs of melanoma may include a mole that is asymmetrical, has irregular borders, is a different color than the surrounding skin, is larger than a pencil eraser, or has a raised or scaly surface. Melanoma can also occur in the eye, mouth, and other parts of the body, and it is important to see a doctor if you have any concerning changes in your skin or other parts of your body.

Retroperitoneal neoplasms are tumors that develop in the retroperitoneal space, which is the area behind the peritoneum, the lining of the abdominal cavity. The retroperitoneum contains various organs and structures, including the kidneys, adrenal glands, and the aorta. Retroperitoneal neoplasms can be primary or secondary. Primary retroperitoneal neoplasms arise from cells within the retroperitoneal space, while secondary retroperitoneal neoplasms are tumors that have spread from other parts of the body to the retroperitoneal space. Retroperitoneal neoplasms can be benign or malignant. Benign retroperitoneal neoplasms are non-cancerous tumors, while malignant retroperitoneal neoplasms are cancerous tumors that can spread to other parts of the body. Symptoms of retroperitoneal neoplasms can vary depending on the location and size of the tumor. Common symptoms include abdominal pain, back pain, and a feeling of fullness or pressure in the abdomen. Other symptoms may include weight loss, fever, and fatigue. Diagnosis of retroperitoneal neoplasms typically involves imaging tests such as CT scans, MRI scans, and ultrasound. Biopsy may also be necessary to confirm the diagnosis. Treatment for retroperitoneal neoplasms depends on the type, size, and location of the tumor, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

In the medical field, protons are subatomic particles that have a positive charge and are found in the nucleus of an atom. They are one of the two types of particles that make up atomic nuclei, the other being neutrons, which have no charge. Protons are important in medical applications because they can be used in a type of radiation therapy called proton therapy. Proton therapy is a type of cancer treatment that uses beams of protons to target and destroy cancer cells while minimizing damage to surrounding healthy tissue. This is because protons have a unique property called the Bragg peak, which allows them to deposit most of their energy at a specific depth in the body before coming to a stop. This makes proton therapy particularly effective for treating certain types of cancer, such as brain tumors and pediatric cancers.

Dysgerminoma is a rare type of ovarian germ cell tumor that typically affects young women in their 20s and 30s. It is a malignant tumor that arises from the germ cells, which are the cells that give rise to eggs in the ovaries. Dysgerminomas are usually large and solid, and they can grow quickly if left untreated. They can also spread to other parts of the body, such as the lungs, liver, and brain. Treatment for dysgerminoma typically involves surgery to remove the tumor, followed by chemotherapy or radiation therapy to kill any remaining cancer cells. In some cases, hormone therapy may also be used. The prognosis for dysgerminoma is generally good, especially if the tumor is caught early and treated promptly.

Ewing sarcoma is a rare type of cancer that affects the bones or soft tissues, particularly in children and young adults. It is named after Dr. James Ewing, who first described the disease in 1921. Ewing sarcoma typically occurs in the long bones of the arms and legs, but it can also affect the pelvis, spine, and other bones. It can also occur in soft tissues, such as the muscles, tendons, and ligaments. The exact cause of Ewing sarcoma is not known, but it is believed to be related to genetic mutations that affect the normal development of bone cells. Symptoms of Ewing sarcoma may include pain, swelling, and tenderness in the affected area, as well as fever, fatigue, and weight loss. Treatment for Ewing sarcoma typically involves a combination of surgery, chemotherapy, and radiation therapy. The specific treatment plan will depend on the location and stage of the cancer, as well as the overall health of the patient. Despite advances in treatment, Ewing sarcoma is still a serious and potentially life-threatening disease.

Tongue neoplasms refer to abnormal growths or tumors that develop on the tongue. These growths can be benign (non-cancerous) or malignant (cancerous). Benign tongue neoplasms include conditions such as fibromas, papillomas, and granulomas, while malignant tongue neoplasms are more serious and can include squamous cell carcinoma, adenoid cystic carcinoma, and others. Tongue neoplasms can cause a variety of symptoms, including difficulty swallowing, pain, and changes in the appearance or texture of the tongue. Treatment for tongue neoplasms depends on the type and stage of the tumor, and may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Antibodies, Monoclonal, Humanized are laboratory-made proteins that are designed to mimic the immune system's ability to fight off harmful pathogens. They are created by fusing a human antibody gene to a mouse antibody gene, resulting in a hybrid antibody that is specific to a particular antigen (a protein on the surface of a pathogen). Humanized monoclonal antibodies are designed to be more similar to human antibodies than their fully mouse counterparts, which can cause unwanted immune reactions in humans. They are used in a variety of medical applications, including cancer treatment, autoimmune diseases, and infectious diseases. Monoclonal antibodies are produced in large quantities in the laboratory and can be administered to patients through injection or infusion. They are a type of targeted therapy, meaning that they specifically target a particular antigen on the surface of a pathogen or cancer cell, rather than affecting the entire immune system.

Parotid neoplasms refer to tumors that develop in the parotid gland, which is one of the largest salivary glands located in the face, just in front of the ear. These tumors can be either benign (non-cancerous) or malignant (cancerous), and they can affect people of all ages. The parotid gland is responsible for producing saliva, which helps to moisten the mouth and throat, and aids in the digestion of food. When a tumor develops in the parotid gland, it can cause a variety of symptoms, including swelling or a mass in the neck, difficulty swallowing, ear pain, and hearing loss. The diagnosis of a parotid neoplasm typically involves a combination of physical examination, imaging studies such as ultrasound or CT scan, and biopsy. Treatment options depend on the type and stage of the tumor, as well as the patient's overall health. Benign tumors may be treated with surgery to remove the tumor, while malignant tumors may require surgery, radiation therapy, or chemotherapy.

Taxoids are a class of natural compounds found in certain plants, particularly in the yew tree family. They are a type of chemotherapy drug that are used to treat various types of cancer, including ovarian, breast, and lung cancer. Taxoids work by interfering with the ability of cancer cells to divide and grow, ultimately leading to their death. The most well-known taxoid is paclitaxel, which is used in the treatment of ovarian and breast cancer. Other taxoids include docetaxel and nab-paclitaxel.

Neoplasms, Squamous Cell are abnormal growths of cells that are derived from the squamous epithelial cells, which are the thin, flat cells that cover the surface of many organs and tissues in the body. Squamous cell neoplasms can occur in various parts of the body, including the skin, lungs, cervix, and head and neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous). Benign squamous cell neoplasms are usually slow-growing and do not spread to other parts of the body. Malignant squamous cell neoplasms, on the other hand, can grow quickly and invade nearby tissues and organs, as well as spread to other parts of the body through the bloodstream or lymphatic system. Squamous cell neoplasms can be treated with a variety of methods, depending on the location, size, and stage of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, immunotherapy, or a combination of these approaches. Early detection and treatment are important for improving the chances of a successful outcome.

Epidural neoplasms are tumors that develop in the epidural space, which is the space between the outer layer of the spinal cord (dura mater) and the bony vertebrae. These tumors can be either benign or malignant and can arise from a variety of different tissue types, including bone, fat, and connective tissue. Epidural neoplasms can cause a range of symptoms, depending on their location and size. Some common symptoms include back pain, weakness or numbness in the legs or arms, difficulty walking, and changes in bowel or bladder function. In some cases, epidural neoplasms can also cause compression of the spinal cord, leading to more severe neurological symptoms. Diagnosis of an epidural neoplasm typically involves a combination of imaging studies, such as MRI or CT scans, and a biopsy to confirm the presence of a tumor. Treatment options for epidural neoplasms depend on the type and location of the tumor, as well as the patient's overall health and preferences. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Erectile dysfunction (ED) is a medical condition in which a man is unable to achieve or maintain an erection sufficient for sexual activity. It is also known as impotence. ED can be caused by a variety of factors, including physical, psychological, and lifestyle factors. Physical causes of ED may include conditions such as diabetes, high blood pressure, and heart disease. Psychological causes may include stress, anxiety, and depression. Lifestyle factors such as smoking, excessive alcohol consumption, and a sedentary lifestyle can also contribute to ED. Treatment for ED may include lifestyle changes, medications, and in some cases, surgery.

Skull neoplasms refer to tumors or abnormal growths that develop in or on the skull. These can be either benign (non-cancerous) or malignant (cancerous). Benign skull neoplasms are usually slow-growing and do not spread to other parts of the body, while malignant skull neoplasms can be aggressive and invade surrounding tissues or spread to other parts of the body through the bloodstream or lymphatic system. Skull neoplasms can occur in any part of the skull, including the bones, nerves, and meninges (the protective membranes that cover the brain and spinal cord). Some common types of skull neoplasms include meningiomas, gliomas, and osteomas. Symptoms of skull neoplasms may include headaches, facial pain or numbness, difficulty with vision or hearing, and changes in behavior or personality. Diagnosis of skull neoplasms typically involves a combination of imaging tests, such as MRI or CT scans, and a biopsy to examine a sample of the tissue. Treatment options for skull neoplasms depend on the type, size, and location of the tumor, as well as the patient's overall health and preferences. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

In the medical field, "Neoplasms, Connective Tissue" refers to abnormal growths or tumors that develop in the connective tissue of the body. Connective tissue is a type of tissue that provides support, structure, and protection to various organs and tissues in the body. Connective tissue neoplasms can occur in various forms, including benign (non-cancerous) and malignant (cancerous) tumors. Benign tumors are usually slow-growing and do not spread to other parts of the body, while malignant tumors can grow quickly and invade nearby tissues and organs, as well as spread to other parts of the body through the bloodstream or lymphatic system. Examples of connective tissue neoplasms include fibromas, lipomas, leiomyomas, and sarcomas. Sarcomas are a type of cancer that develops in the connective tissue, including bone, muscle, fat, and blood vessels. The diagnosis and treatment of connective tissue neoplasms depend on the type, size, location, and stage of the tumor, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, and targeted therapy.

Organoplatinum compounds are chemical compounds that contain a carbon atom bonded to a platinum atom. They are commonly used in the medical field as chemotherapy drugs to treat various types of cancer, including ovarian, testicular, and lung cancer. Organoplatinum compounds work by interfering with the growth and division of cancer cells, ultimately leading to their death. Some examples of organoplatinum compounds used in medicine include cisplatin, carboplatin, and oxaliplatin. These drugs can have significant side effects, including nausea, vomiting, and kidney damage, but they are often effective at stopping the growth of cancer cells and improving outcomes for patients.

Craniopharyngioma is a rare, slow-growing benign tumor that develops in the craniopharyngeal region, which is the area where the brain meets the pituitary gland. It is classified into two types: adamantinomatous and papillary. The tumor can cause a variety of symptoms, including headaches, vision problems, hormonal imbalances, and changes in appetite and weight. It can also cause fluid buildup in the brain, leading to increased pressure and potentially life-threatening complications. Treatment options for craniopharyngioma include surgery, radiation therapy, and medication to manage symptoms. The choice of treatment depends on the size and location of the tumor, as well as the patient's overall health and preferences.

Radioisotopes are isotopes of an element that emit radiation, such as alpha particles, beta particles, or gamma rays. In the medical field, radioisotopes are used in a variety of diagnostic and therapeutic applications. In diagnostic imaging, radioisotopes are used to create images of the body's internal structures. For example, a radioisotope such as technetium-99m can be injected into the bloodstream and then detected by a gamma camera to create an image of the heart, lungs, or other organs. This type of imaging is commonly used to diagnose conditions such as cancer, heart disease, and bone disorders. Radioisotopes are also used in therapeutic applications, such as radiation therapy for cancer. In this treatment, a radioisotope is introduced into the body, usually by injection or inhalation, and then targeted to a specific area of the body where it emits radiation that destroys cancer cells. Radioisotopes are also used in targeted radionuclide therapy, where a radioisotope is attached to a molecule that specifically targets cancer cells, allowing for more precise delivery of radiation. Overall, radioisotopes play a critical role in medical imaging and therapy, allowing for the diagnosis and treatment of a wide range of conditions.

Leucovorin, also known as folic acid or folinic acid, is a water-soluble vitamin that is important for the synthesis of DNA and RNA. It is used in the treatment of certain types of cancer, such as methotrexate-induced myelosuppression, and in the prevention of side effects from chemotherapy. Leucovorin is also used to treat vitamin B12 deficiency and to prevent neural tube defects in pregnant women. It is available as a medication and can be taken by mouth or given intravenously.

Carcinoma, Intraductal, Noninfiltrating (CIN) is a type of cancer that originates in the lining of the milk ducts in the breast. It is also known as ductal carcinoma in situ (DCIS). CIN is considered a pre-cancerous condition because it has the potential to develop into invasive breast cancer if left untreated. However, it is important to note that not all cases of CIN will progress to invasive cancer. CIN is typically detected through a mammogram, which is an X-ray of the breast. If CIN is detected, a biopsy may be performed to confirm the diagnosis and determine the extent of the disease. Treatment for CIN may include surgery, radiation therapy, or hormone therapy, depending on the specific circumstances of the case. It is important for women to be aware of the signs and symptoms of breast cancer and to have regular mammograms as part of their routine healthcare. Early detection and treatment of breast cancer can improve outcomes and increase the chances of a successful recovery.

Otorhinolaryngologic neoplasms refer to tumors or growths that develop in the head and neck region, specifically in the ear, nose, throat, and related structures. These neoplasms can be benign or malignant, and can affect any part of the head and neck region, including the sinuses, salivary glands, thyroid gland, and larynx. Some common examples of otorhinolaryngologic neoplasms include: * Nasopharyngeal carcinoma * Laryngeal carcinoma * Sinusitis * Nasal polyps * Thyroid cancer * Salivary gland tumors The diagnosis and treatment of otorhinolaryngologic neoplasms typically involve a combination of medical and surgical interventions, depending on the type and location of the tumor, as well as the patient's overall health and medical history. In some cases, radiation therapy or chemotherapy may also be used to treat these neoplasms.

Retinal neoplasms refer to abnormal growths or tumors that develop on the retina, which is the light-sensitive layer of tissue at the back of the eye. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) in nature. Retinal neoplasms can occur in various parts of the retina, including the choroid, the layer of blood vessels and connective tissue beneath the retina, and the pigment epithelium, the layer of cells that covers the retina and helps to nourish and maintain it. Retinal neoplasms can cause a range of symptoms, depending on their size, location, and type. Some common symptoms include changes in vision, such as blurred vision, floaters, or flashes of light, as well as pain or discomfort in the eye. Diagnosis of retinal neoplasms typically involves a comprehensive eye exam, including dilated eye exams, imaging tests such as optical coherence tomography (OCT) or fluorescein angiography, and sometimes a biopsy to confirm the diagnosis. Treatment for retinal neoplasms depends on the type, size, and location of the tumor, as well as the patient's overall health and preferences. Options may include observation, laser therapy, cryotherapy, radiation therapy, or surgery.

Endometrial neoplasms refer to abnormal growths or tumors that develop in the lining of the uterus, known as the endometrium. These neoplasms can be benign (non-cancerous) or malignant (cancerous). Endometrial neoplasms are classified based on their degree of malignancy, with the most common types being endometrial hyperplasia and endometrial cancer. Endometrial hyperplasia is a condition in which the cells in the endometrium grow abnormally, but do not invade into nearby tissues. Endometrial cancer, on the other hand, is a more serious condition in which the abnormal cells invade into nearby tissues and can spread to other parts of the body. Endometrial neoplasms can cause a variety of symptoms, including abnormal vaginal bleeding, pelvic pain, and pain during sexual intercourse. Diagnosis typically involves a combination of physical examination, imaging studies, and biopsy of the endometrial tissue. Treatment for endometrial neoplasms depends on the type, stage, and severity of the condition. Benign neoplasms may be treated with medication, surgery, or a combination of both. Malignant neoplasms may require more aggressive treatment, such as surgery, radiation therapy, or chemotherapy. Early detection and treatment are important for improving outcomes and reducing the risk of complications.

Facial neoplasms refer to abnormal growths or tumors that develop on the face. These growths can be benign (non-cancerous) or malignant (cancerous) and can occur on any part of the face, including the skin, bones, muscles, and nerves. Facial neoplasms can be further classified based on their location, size, and type. Some common types of facial neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, lipomas, hemangiomas, and cysts. The diagnosis of facial neoplasms typically involves a physical examination, medical history, and imaging studies such as X-rays, CT scans, or MRI scans. Biopsy may also be necessary to confirm the diagnosis and determine the type of neoplasm. Treatment for facial neoplasms depends on the type, size, and location of the growth, as well as the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. In some cases, monitoring the growth over time may be the best course of action.

Exophthalmos is a medical condition characterized by the protrusion or bulging of one or both eyes forward from the orbit. It is also known as proptosis or exophthalmos bulbi. Exophthalmos can be caused by a variety of factors, including inflammation or swelling of the orbit, tumors or masses in the orbit or surrounding tissues, Graves' disease, thyroid eye disease, or other eye or orbital disorders. In some cases, exophthalmos may be a symptom of a more serious underlying condition, such as a brain tumor or an infection of the orbit. Treatment for exophthalmos depends on the underlying cause and may include medications, surgery, or other therapies.

Bronchial neoplasms refer to abnormal growths or tumors that develop in the bronchial tubes, which are the airways that carry air from the trachea (windpipe) to the lungs. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Benign bronchial neoplasms, also known as bronchial adenomas, are relatively rare and usually do not cause any symptoms. However, they can sometimes cause blockages in the bronchial tubes, leading to difficulty breathing or recurrent infections. Malignant bronchial neoplasms, also known as bronchogenic carcinomas, are more common and can be further classified into several subtypes, including small cell lung cancer and non-small cell lung cancer. These tumors can grow rapidly and spread to other parts of the body, leading to serious health problems and potentially death if left untreated. Diagnosis of bronchial neoplasms typically involves a combination of imaging tests, such as chest X-rays or CT scans, and bronchoscopy, a procedure in which a thin, flexible tube is inserted into the bronchial tubes to visualize the tumors and take biopsies for further analysis. Treatment options for bronchial neoplasms depend on the type, size, and location of the tumor, as well as the overall health of the patient.

Ruthenium radioisotopes are radioactive isotopes of the element ruthenium that are used in medical applications. Ruthenium is a chemical element with the symbol Ru and atomic number 44. It is a hard, blue-gray metal that is resistant to corrosion and has a high melting point. There are several different radioisotopes of ruthenium that are used in medicine, including ruthenium-97, ruthenium-99m, and ruthenium-106. These radioisotopes are used in a variety of medical applications, including diagnostic imaging, radiation therapy, and as sources of radiation for certain types of medical equipment. Ruthenium-97 is a short-lived radioisotope that is used in diagnostic imaging to help doctors visualize the inside of the body. It is typically produced by bombarding a target with high-energy protons, and is then used in a technique called positron emission tomography (PET) to create detailed images of the body's organs and tissues. Ruthenium-99m is a more stable radioisotope that is used in diagnostic imaging to help doctors diagnose a wide range of conditions, including bone disorders, heart disease, and cancer. It is typically produced by bombarding a target with neutrons, and is then used in a technique called single-photon emission computed tomography (SPECT) to create detailed images of the body's organs and tissues. Ruthenium-106 is a long-lived radioisotope that is used in radiation therapy to treat certain types of cancer. It is typically produced by bombarding a target with high-energy protons, and is then used to deliver a high dose of radiation to the cancer cells, while minimizing damage to surrounding healthy tissue. Overall, ruthenium radioisotopes play an important role in the medical field, and are used in a variety of diagnostic and therapeutic applications to help doctors diagnose and treat a wide range of conditions.

Monoclonal antibodies (mAbs) are laboratory-made proteins that can mimic the immune system's ability to fight off harmful pathogens, such as viruses and bacteria. They are produced by genetically engineering cells to produce large quantities of a single type of antibody, which is specific to a particular antigen (a molecule that triggers an immune response). In the medical field, monoclonal antibodies are used to treat a variety of conditions, including cancer, autoimmune diseases, and infectious diseases. They can be administered intravenously, intramuscularly, or subcutaneously, depending on the condition being treated. Monoclonal antibodies work by binding to specific antigens on the surface of cells or pathogens, marking them for destruction by the immune system. They can also block the activity of specific molecules involved in disease processes, such as enzymes or receptors. Overall, monoclonal antibodies have revolutionized the treatment of many diseases, offering targeted and effective therapies with fewer side effects than traditional treatments.

Carmustine is a chemotherapy drug that is used to treat various types of cancer, including brain tumors, Hodgkin's lymphoma, and non-Hodgkin's lymphoma. It is also known by its brand name BCNU. Carmustine works by interfering with the growth and division of cancer cells, which can cause them to die or stop growing. It is usually given intravenously (IV) or as a solution that is injected directly into the tumor. Carmustine can cause side effects, including nausea, vomiting, hair loss, fatigue, and a decreased white blood cell count. It can also cause damage to healthy cells in the brain, which can cause symptoms such as headache, dizziness, and confusion. Carmustine is often used in combination with other chemotherapy drugs or radiation therapy to increase its effectiveness and reduce the risk of side effects. It is important to carefully follow the instructions of a healthcare provider when taking this medication.

Neuroectodermal tumors, primitive, are a group of rare and aggressive tumors that arise from the neural crest cells, which are a type of embryonic cell that gives rise to the nervous system and other tissues in the body. These tumors can occur in various parts of the body, including the brain, spinal cord, and peripheral nerves. Primitive neuroectodermal tumors (PNETs) are a subtype of neuroectodermal tumors that are characterized by their aggressive behavior and tendency to spread quickly to other parts of the body. PNETs can occur in both children and adults, and they are often difficult to diagnose and treat. The diagnosis of PNETs is typically made through a combination of imaging studies, such as MRI or CT scans, and a biopsy of the tumor tissue. Treatment for PNETs may include surgery, chemotherapy, radiation therapy, or a combination of these approaches. The prognosis for PNETs depends on several factors, including the location and size of the tumor, the age and overall health of the patient, and the response to treatment.

Bile duct neoplasms refer to tumors that develop in the bile ducts, which are the tubes that carry bile from the liver to the small intestine. These tumors can be either benign or malignant, and they can occur in any part of the bile duct system, including the intrahepatic bile ducts (which are located within the liver), the extrahepatic bile ducts (which are located outside the liver), and the ampulla of Vater (which is the point where the common bile duct and the main pancreatic duct join). Bile duct neoplasms can present with a variety of symptoms, depending on the location and size of the tumor. Some common symptoms include jaundice (yellowing of the skin and eyes), abdominal pain, weight loss, and fever. Diagnosis typically involves imaging studies such as ultrasound, CT scan, or MRI, as well as biopsy to confirm the presence of cancer cells. Treatment for bile duct neoplasms depends on the type and stage of the tumor, as well as the overall health of the patient. Options may include surgery, chemotherapy, radiation therapy, or a combination of these approaches. The prognosis for bile duct neoplasms varies widely, depending on the specific type and stage of the tumor, as well as the patient's age, overall health, and response to treatment.

Mesothelioma is a rare and aggressive type of cancer that develops in the mesothelium, which is the thin layer of tissue that covers most of the internal organs in the body. The most common type of mesothelioma is pleural mesothelioma, which affects the lining of the lungs (pleura). Other types of mesothelioma can develop in the lining of the abdomen (peritoneum), the lining of the heart (pericardium), and the lining of the testicles (tunica vaginalis). Mesothelioma is almost always caused by exposure to asbestos, a naturally occurring mineral that was widely used in construction, shipbuilding, and other industries until the 1970s. When asbestos fibers are inhaled or ingested, they can become embedded in the mesothelium and cause damage that leads to the development of cancerous tumors. Symptoms of mesothelioma may not appear until many years after exposure to asbestos, and can include shortness of breath, chest pain, coughing, and weight loss. Treatment options for mesothelioma include surgery, chemotherapy, radiation therapy, and targeted therapy. However, mesothelioma is often difficult to diagnose and treat, and the prognosis is generally poor.

Octreotide is a synthetic hormone that is used in the medical field to treat various conditions related to the endocrine system. It is a somatostatin analog, which means that it is similar in structure to the natural hormone somatostatin, which is produced by the pancreas and other glands in the body. Octreotide is primarily used to treat acromegaly, a hormonal disorder that occurs when the pituitary gland produces too much growth hormone. It is also used to treat carcinoid tumors, which are tumors that produce excessive amounts of hormones, and to control diarrhea caused by certain medical conditions, such as inflammatory bowel disease or radiation therapy. Octreotide is usually administered as a subcutaneous injection, which means that it is injected just under the skin. It can also be administered as an intravenous infusion or as a nasal spray. The dosage and frequency of administration depend on the specific condition being treated and the individual patient's response to the medication.

Rectal diseases refer to medical conditions that affect the rectum, which is the final part of the large intestine. The rectum is responsible for storing feces until they are eliminated from the body through the anus. Rectal diseases can be acute or chronic and can range from minor to severe. Some common rectal diseases include: 1. Hemorrhoids: Swollen veins in the rectum or anus that can cause pain, itching, and bleeding. 2. Anal fissures: Tears in the lining of the anus that can cause pain and bleeding during bowel movements. 3. Fistulas: Abnormal connections between the rectum and other organs or tissues, such as the skin or vagina. 4. Polyps: Non-cancerous growths in the rectum that can cause bleeding or blockage. 5. Inflammatory bowel disease (IBD): Chronic conditions that cause inflammation in the rectum and other parts of the digestive tract, including Crohn's disease and ulcerative colitis. 6. Rectal cancer: A type of cancer that starts in the rectum and can spread to other parts of the body. Rectal diseases can be diagnosed through a physical examination, medical imaging tests, and other diagnostic procedures. Treatment options depend on the specific disease and may include medications, surgery, or other therapies.

Neurocytoma is a rare, slow-growing tumor that arises from the nerve cells (neurons) in the brain or spinal cord. It is classified as a type of glial tumor, which are tumors that arise from the supportive cells (glial cells) that surround and support neurons. Neurocytomas are typically found in the temporal lobe of the brain, although they can also occur in other parts of the brain and spinal cord. They are usually benign (non-cancerous), but in some cases, they can be malignant (cancerous). Symptoms of neurocytoma may include headaches, seizures, vision problems, and changes in personality or behavior. Diagnosis is typically made through imaging tests such as MRI or CT scans, and a biopsy may be performed to confirm the diagnosis. Treatment for neurocytoma typically involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to prevent the tumor from returning. The prognosis for neurocytoma is generally good, with most patients experiencing a good quality of life after treatment.

Carcinoma, Transitional Cell is a type of cancer that originates in the transitional cells lining the urinary tract, including the bladder, ureters, and renal pelvis. These cells are responsible for regulating the flow of urine and lining the inner surface of the urinary tract. Transitional cell carcinoma can develop in any part of the urinary tract, but it is most commonly found in the bladder. It is the most common type of bladder cancer and can be either non-invasive (in situ) or invasive (infiltrating) depending on whether the cancer cells have spread beyond the lining of the bladder. Symptoms of transitional cell carcinoma may include blood in the urine, frequent urination, pain or burning during urination, and abdominal pain or discomfort. Diagnosis typically involves a combination of physical examination, imaging studies, and biopsy. Treatment for transitional cell carcinoma may include surgery, chemotherapy, radiation therapy, or a combination of these approaches, depending on the stage and location of the cancer. Early detection and treatment are important for improving outcomes and reducing the risk of recurrence.

Carcinoma, Hepatocellular is a type of cancer that originates in the liver cells, specifically in the cells that line the small blood vessels within the liver. It is the most common type of liver cancer and is often associated with chronic liver disease, such as cirrhosis or hepatitis B or C infection. The cancer cells in hepatocellular carcinoma can grow and spread to other parts of the body, including the lungs, bones, and lymph nodes. Symptoms of hepatocellular carcinoma may include abdominal pain, weight loss, jaundice (yellowing of the skin and eyes), and fatigue. Treatment options for hepatocellular carcinoma may include surgery, chemotherapy, radiation therapy, targeted therapy, and liver transplantation. The choice of treatment depends on the stage and location of the cancer, as well as the overall health of the patient.

Astatine is a radioactive element that is not commonly used in the medical field. It has atomic number 85 and is a member of the halogen group. Astatine is highly toxic and has a very short half-life, which means that it decays rapidly into other elements. As a result, it is not used in medical treatments or diagnostic procedures. However, astatine has been studied for its potential use in cancer therapy, as it has been shown to be highly effective in killing cancer cells.

Fibromatosis, aggressive, also known as desmoid tumor, is a rare type of benign (non-cancerous) tumor that arises from fibrous connective tissue. These tumors can grow quickly and aggressively, invading surrounding tissues and potentially causing serious complications. They can occur in any part of the body, but are most commonly found in the abdominal wall, muscles, and ligaments. Treatment options for aggressive fibromatosis may include surgery, radiation therapy, and chemotherapy, depending on the size and location of the tumor and the patient's overall health.

Goserelin is a synthetic hormone used in the medical field to treat various conditions related to the endocrine system. It is a gonadotropin-releasing hormone (GnRH) agonist, which means it mimics the action of GnRH, a hormone produced by the hypothalamus that regulates the production of sex hormones by the pituitary gland. Goserelin is commonly used to treat prostate cancer by reducing the production of testosterone, which can slow the growth of cancer cells. It is also used to treat uterine fibroids, endometriosis, and breast cancer in women. In addition, goserelin is used to treat precocious puberty in children. Goserelin is usually administered as an injection, either subcutaneously (under the skin) or intramuscularly (into a muscle). The frequency and duration of treatment depend on the condition being treated and the individual patient's response to the medication.

Lymphoma, Extranodal NK-T-Cell is a type of cancer that affects the immune system, specifically the lymphocytes, which are a type of white blood cell. It is a rare type of lymphoma that affects the cells called natural killer (NK) cells, which are a type of immune cell that helps the body fight off infections and diseases. Extranodal NK/T-cell lymphoma typically occurs in the nose and throat, but it can also affect other parts of the body, such as the skin, liver, and gastrointestinal tract. The symptoms of this type of lymphoma can vary depending on where it occurs, but they may include swelling or a lump in the affected area, difficulty swallowing, and unexplained weight loss. Treatment for extranodal NK/T-cell lymphoma typically involves a combination of chemotherapy, radiation therapy, and stem cell transplantation. The specific treatment plan will depend on the stage and location of the cancer, as well as the overall health of the patient.

Nitroimidazoles are a class of synthetic organic compounds that contain a nitro group (-NO2) and an imidazole ring. They are used in the medical field as antibiotics and antiprotozoal drugs to treat a variety of infections caused by bacteria and parasites. Some common examples of nitroimidazoles used in medicine include metronidazole, tinidazole, and ornidazole. These drugs are effective against a range of bacterial and parasitic infections, including giardiasis, trichomoniasis, bacterial vaginosis, and certain types of anaerobic bacterial infections. Nitroimidazoles work by inhibiting the growth and reproduction of bacteria and parasites. They are typically administered orally or intravenously, depending on the specific infection being treated and the severity of the illness. Side effects of nitroimidazoles may include nausea, vomiting, diarrhea, and headache, although these are generally mild and temporary.

Flutamide is a medication that is used to treat prostate cancer in men. It is a type of drug called an androgen receptor antagonist, which means that it blocks the effects of male hormones (androgens) on the prostate gland. Flutamide is usually used in combination with other medications or surgery to treat prostate cancer. It can help to slow the growth of cancer cells and reduce the risk of the cancer spreading to other parts of the body. Flutamide is usually taken by mouth as tablets, and the dosage and duration of treatment will depend on the individual patient's condition and response to the medication. It is important to follow the instructions of a healthcare professional when taking flutamide, as it can cause side effects such as breast tenderness, breast enlargement, and hot flashes.

Chondrosarcoma is a type of cancer that arises from cartilage cells in the body. It is a rare cancer that typically affects adults, although it can occur in children as well. Chondrosarcoma can develop in any part of the body where cartilage is present, but it most commonly occurs in the bones of the pelvis, shoulder, and thigh. Chondrosarcoma is classified into different grades based on how aggressive the cancer is and how quickly it grows. Grade I chondrosarcomas are slow-growing and have a good prognosis, while grade II and III chondrosarcomas are more aggressive and have a poorer prognosis. Treatment for chondrosarcoma typically involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to kill any remaining cancer cells. The prognosis for chondrosarcoma depends on the grade of the cancer, the location of the tumor, and the patient's overall health.

Lutetium is a chemical element with the symbol Lu and atomic number 71. It is a rare earth element and is not commonly used in the medical field. However, there is one medical application of lutetium that has gained some attention in recent years. Lutetium-177 (Lu-177) is a radioactive isotope of lutetium that has been used in targeted radionuclide therapy (TRT) for the treatment of certain types of cancer. TRT involves the use of radioactive isotopes to target and destroy cancer cells while minimizing damage to healthy tissue. Lu-177 is typically attached to a molecule that is specific to a particular type of cancer cell, allowing it to be selectively delivered to the cancer cells. Once inside the cancer cells, the radioactive decay of Lu-177 releases energy that damages the cancer cells and causes them to die. Lu-177 has been used to treat several types of cancer, including neuroendocrine tumors, prostate cancer, and multiple myeloma. It has shown promise as a treatment option for patients who have not responded to other forms of therapy or who are not eligible for surgery or radiation therapy.

An acoustic neuroma, also known as a vestibular schwannoma, is a benign (non-cancerous) tumor that develops on the vestibular nerve, which is responsible for transmitting signals from the inner ear to the brain. The tumor typically grows slowly and can cause a variety of symptoms, including hearing loss, ringing in the ears (tinnitus), dizziness, and balance problems. In some cases, an acoustic neuroma can cause pressure on the brainstem, which can lead to more serious symptoms such as double vision, weakness on one side of the face, and difficulty speaking. Treatment options for an acoustic neuroma may include observation, medication, radiation therapy, or surgery.

Epirubicin is an anthracycline chemotherapy drug used to treat various types of cancer, including breast cancer, ovarian cancer, and stomach cancer. It works by interfering with the production of DNA and RNA, which are essential for the growth and division of cancer cells. Epirubicin is usually administered intravenously and can cause side effects such as hair loss, nausea, vomiting, and low white blood cell counts. It is also known by the brand name Ellence.

Tumor suppressor protein p53 is a protein that plays a crucial role in regulating cell growth and preventing the development of cancer. It is encoded by the TP53 gene and is one of the most commonly mutated genes in human cancer. The p53 protein acts as a "guardian of the genome" by detecting DNA damage and initiating a series of cellular responses to repair the damage or trigger programmed cell death (apoptosis) if the damage is too severe. This helps to prevent the accumulation of mutations in the DNA that can lead to the development of cancer. In addition to its role in preventing cancer, p53 also plays a role in regulating cell cycle progression, DNA repair, and the response to cellular stress. Mutations in the TP53 gene can lead to the production of a non-functional or mutated p53 protein, which can result in the loss of these important functions and contribute to the development of cancer. Overall, the p53 protein is a critical regulator of cell growth and survival, and its dysfunction is a common feature of many types of cancer.

Neoplasms, neuroepithelial, also known as neuroepithelial tumors, are a type of cancer that arises from the cells that line the cavities of the brain and spinal cord. These tumors can be either benign (non-cancerous) or malignant (cancerous). Neuroepithelial tumors can be further classified based on their location, size, and cell type. Some common types of neuroepithelial tumors include gliomas (tumors that arise from glial cells), meningiomas (tumors that arise from cells that line the meninges, the protective membranes that surround the brain and spinal cord), and schwannomas (tumors that arise from Schwann cells, which are cells that wrap around nerve fibers). Symptoms of neuroepithelial tumors can vary depending on the location and size of the tumor, but may include headaches, seizures, changes in vision or hearing, and difficulty with balance or coordination. Treatment options for neuroepithelial tumors may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Rhabdomyosarcoma, Embryonal is a type of cancer that arises from the cells that form skeletal muscle. It is the most common type of soft tissue sarcoma in children and adolescents, and it can occur in any part of the body, but it is most commonly found in the head and neck, genitourinary system, and retroperitoneum. Rhabdomyosarcoma, Embryonal is characterized by the presence of cells that resemble immature muscle cells, or rhabdomyoblasts. These cells can form tumors that are either solid or have a mixture of solid and cystic areas. The tumors can be aggressive and may spread to other parts of the body through the bloodstream or lymphatic system. Treatment for Rhabdomyosarcoma, Embryonal typically involves a combination of surgery, chemotherapy, and radiation therapy. The specific treatment plan will depend on the location and stage of the tumor, as well as the overall health of the patient. In some cases, stem cell transplantation may also be used as part of the treatment plan.

Gastrointestinal neoplasms refer to tumors or abnormal growths that develop in the lining of the digestive tract, including the esophagus, stomach, small intestine, large intestine, rectum, and anus. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Gastrointestinal neoplasms can cause a variety of symptoms, depending on the location and size of the tumor. Some common symptoms include abdominal pain, changes in bowel habits, nausea and vomiting, weight loss, and anemia. Diagnosis of gastrointestinal neoplasms typically involves a combination of medical history, physical examination, imaging tests such as endoscopy or CT scans, and biopsy. Treatment options for gastrointestinal neoplasms depend on the type, size, and location of the tumor, as well as the overall health of the patient. Treatment may include surgery, chemotherapy, radiation therapy, or a combination of these approaches.

Lymphoma, B-Cell, Marginal Zone is a type of cancer that affects the lymphatic system, which is a part of the immune system. It is a type of B-cell lymphoma, which means that it starts in the B cells, a type of white blood cell that helps the body fight infections. In marginal zone lymphoma, the cancer cells develop in the marginal zone, which is a part of the lymph node that filters out foreign substances from the blood. This type of lymphoma is usually slow-growing and may not cause symptoms in the early stages. However, as the cancer progresses, it can cause swelling of the lymph nodes, fatigue, fever, and night sweats. Treatment for marginal zone lymphoma may include chemotherapy, radiation therapy, and targeted therapy, which uses drugs to specifically target the cancer cells. The choice of treatment depends on the stage and severity of the cancer, as well as the patient's overall health.

Rhenium is a chemical element with the symbol Re and atomic number 75. It is a rare, silvery-white, transition metal that is found in the Earth's crust in small amounts. In the medical field, rhenium has been studied for its potential use in cancer treatment. It has been shown to have anti-tumor properties and may be effective in treating certain types of cancer, such as prostate cancer and lung cancer. Rhenium has also been used in the development of medical imaging agents, such as radiolabeled rhenium complexes, which can be used to detect and diagnose certain diseases. However, more research is needed to fully understand the potential uses and safety of rhenium in medicine.

Osteosarcoma is a type of cancer that starts in the cells that make up the bones. It is the most common type of bone cancer in children and adolescents, and it can occur in any bone in the body, but it most often affects the long bones of the arms and legs, such as the femur and tibia. Osteosarcoma usually develops in the metaphysis, which is the area of the bone where it is still growing and developing. The cancer cells can spread to the surrounding tissue and bone, and in some cases, they can also spread to other parts of the body through the bloodstream or lymphatic system. Symptoms of osteosarcoma may include pain and swelling in the affected bone, difficulty moving the affected joint, and the appearance of a lump or mass near the bone. Diagnosis is typically made through a combination of imaging tests, such as X-rays and MRI scans, and a biopsy to examine a sample of the tumor tissue. Treatment for osteosarcoma typically involves a combination of surgery, chemotherapy, and radiation therapy. The goal of treatment is to remove as much of the cancer as possible while minimizing damage to the surrounding healthy tissue. The prognosis for osteosarcoma depends on several factors, including the stage of the cancer at diagnosis, the location of the tumor, and the patient's overall health.

Histiocytoma, Malignant Fibrous is a rare type of cancer that arises from the histiocytes, which are a type of white blood cell that plays a role in the immune system. It is also known as malignant fibrous histiocytoma (MFH) or undifferentiated pleomorphic sarcoma (UPS). Malignant fibrous histiocytoma typically affects adults and is most commonly found in the deep soft tissues of the body, such as the muscles, tendons, and ligaments. It can also occur in the bone, lung, and other organs. The symptoms of malignant fibrous histiocytoma can vary depending on the location of the tumor and its size. Common symptoms include pain, swelling, and a mass or lump in the affected area. In some cases, the tumor may spread to other parts of the body, leading to additional symptoms such as weakness, fatigue, and weight loss. Treatment for malignant fibrous histiocytoma typically involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to kill any remaining cancer cells. The prognosis for malignant fibrous histiocytoma depends on several factors, including the size and location of the tumor, the stage of the cancer, and the patient's overall health.

Copper radioisotopes are radioactive isotopes of the element copper that are used in medical imaging and therapy. These isotopes have specific properties that make them useful for certain medical applications, such as their ability to emit gamma rays or positrons, which can be detected by medical imaging equipment. One common copper radioisotope used in medical imaging is copper-64 (64Cu), which is often used in positron emission tomography (PET) scans to study the function of organs and tissues in the body. Copper-64 is taken up by cells in the body and emits positrons, which are detected by the PET scanner. This allows doctors to visualize the distribution of the isotope in the body and get information about the function of the organs and tissues. Copper radioisotopes are also used in targeted radionuclide therapy, a type of cancer treatment that involves delivering a radioactive substance directly to cancer cells. Copper-67 (67Cu) is one example of a copper radioisotope that is used in this way. It is taken up by cancer cells and emits gamma rays, which can damage the cancer cells and kill them. This type of therapy is often used to treat certain types of cancer, such as non-Hodgkin's lymphoma and multiple myeloma. Overall, copper radioisotopes play an important role in medical imaging and therapy, allowing doctors to diagnose and treat a variety of medical conditions.

An ACTH-secreting pituitary adenoma is a type of benign tumor that develops in the pituitary gland, a small endocrine gland located at the base of the brain. This type of adenoma produces excess amounts of adrenocorticotropic hormone (ACTH), which stimulates the adrenal glands to produce cortisol, a hormone that regulates metabolism and the body's response to stress. The overproduction of cortisol in individuals with an ACTH-secreting pituitary adenoma can lead to a variety of symptoms, including weight gain, high blood pressure, muscle weakness, fatigue, and mood changes. In some cases, the excess cortisol production can also cause the skin to become thin and fragile, and the bones to become weak and brittle. Treatment for an ACTH-secreting pituitary adenoma typically involves surgery to remove the tumor, followed by medication to manage any remaining symptoms or to prevent the tumor from growing back. In some cases, radiation therapy may also be used to treat the tumor.

Stomach neoplasms refer to abnormal growths or tumors that develop in the lining of the stomach. These growths can be either benign (non-cancerous) or malignant (cancerous). Stomach neoplasms can occur in different parts of the stomach, including the stomach lining, the muscular wall of the stomach, and the glands that produce stomach acid. Some common types of stomach neoplasms include gastric adenocarcinoma (a type of cancer that starts in the glandular cells of the stomach lining), gastric lymphoma (a type of cancer that starts in the lymphatic cells of the stomach), and gastric stromal tumors (benign tumors that develop in the connective tissue of the stomach). Stomach neoplasms can cause a variety of symptoms, including abdominal pain, nausea, vomiting, weight loss, and loss of appetite. Diagnosis typically involves a combination of medical history, physical examination, imaging tests (such as endoscopy or CT scan), and biopsy. Treatment for stomach neoplasms depends on the type, size, and location of the tumor, as well as the overall health of the patient. Treatment options may include surgery, chemotherapy, radiation therapy, or a combination of these approaches.

Germinoma is a type of germ cell tumor that arises from the germ cells, which are the cells that give rise to eggs or sperm in females and males, respectively. Germinomas are most commonly found in the brain and spinal cord, but they can also occur in other parts of the body, such as the testicles, ovaries, and mediastinum. Germinomas are typically slow-growing tumors and are often diagnosed in young adults and children. They are highly curable with radiation therapy, and the prognosis for patients with germinomas is generally very good if the tumor is detected and treated early. In some cases, germinomas can produce hormones, such as alpha-fetoprotein (AFP) or human chorionic gonadotropin (hCG), which can cause symptoms such as abdominal pain, nausea, and vomiting. These symptoms may be a sign of a more advanced tumor or may be caused by the hormones produced by the tumor.

Tegafur is a chemotherapy drug that is used to treat various types of cancer, including colorectal cancer, breast cancer, and lung cancer. It is a prodrug of 5-fluorouracil (5-FU), which is a medication that works by slowing or stopping the growth of cancer cells in the body. Tegafur is usually given in combination with other chemotherapy drugs, such as leucovorin, to increase its effectiveness and reduce the risk of side effects. It is usually taken orally, although it can also be given intravenously or by injection. Tegafur is a potent medication that can cause a range of side effects, including nausea, vomiting, diarrhea, loss of appetite, fatigue, and hair loss. It can also cause more serious side effects, such as bone marrow suppression, which can lead to anemia, neutropenia, and thrombocytopenia. It is important to note that tegafur is not suitable for everyone, and its use should be carefully considered by a healthcare professional based on the individual's medical history and current health status.

Nervous system neoplasms refer to tumors or abnormal growths that develop in the nervous system, which includes the brain, spinal cord, and nerves. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) and can affect any part of the nervous system. The nervous system is responsible for transmitting signals throughout the body, controlling movement, sensation, and thought. When a neoplasm develops in the nervous system, it can disrupt these functions and cause a range of symptoms, depending on the location and size of the tumor. Some common symptoms of nervous system neoplasms include headaches, seizures, changes in sensation or movement, difficulty speaking or swallowing, and changes in behavior or personality. Diagnosis typically involves imaging tests such as MRI or CT scans, as well as a biopsy to confirm the presence of a tumor. Treatment for nervous system neoplasms depends on the type, location, and size of the tumor, as well as the patient's overall health. Options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. In some cases, a watchful waiting approach may be appropriate if the tumor is small and not causing symptoms.

Synovitis, Pigmented Villonodular (PVNS) is a rare, benign (non-cancerous) condition that affects the synovium, which is the lining of the joint capsule. PVNS is characterized by the formation of abnormal blood vessels and pigmented nodules (lumps) in the synovium, which can cause inflammation and pain in the affected joint. PVNS can occur in any joint, but it most commonly affects the knee, elbow, and ankle. The condition can be classified into two types: localized PVNS, which affects only one joint, and diffuse PVNS, which affects multiple joints and can also involve other organs such as the liver and lung. PVNS is usually diagnosed through a combination of physical examination, imaging studies such as MRI or X-ray, and a biopsy of the affected tissue. Treatment options for PVNS include surgery to remove the affected tissue, radiation therapy, and medications to manage pain and inflammation. In some cases, the condition may recur after treatment, and long-term follow-up is necessary to monitor for any recurrence.

Neovascularization, pathologic, refers to the abnormal growth of new blood vessels in the body. This can occur in response to a variety of factors, including injury, inflammation, and certain diseases. In some cases, neovascularization can be a normal part of the healing process, but in other cases it can be a sign of a more serious underlying condition. Pathologic neovascularization is often associated with conditions such as cancer, diabetes, and age-related macular degeneration. It can also be seen in the development of certain types of tumors, where the new blood vessels help to provide the tumor with the nutrients and oxygen it needs to grow. Treatment for pathologic neovascularization may involve medications, laser therapy, or surgery, depending on the underlying cause and the severity of the condition.

Lymphoma, Large B-Cell, Diffuse is a type of cancer that affects the lymphatic system, which is a part of the immune system. It is characterized by the uncontrolled growth of abnormal B cells, which are a type of white blood cell that helps the body fight infections. In diffuse large B-cell lymphoma (DLBCL), the cancer cells are found throughout the lymph nodes and other lymphoid tissues, such as the spleen and bone marrow. This type of lymphoma is often aggressive and can spread quickly to other parts of the body. DLBCL is typically diagnosed through a combination of physical examination, imaging tests, and a biopsy of the affected tissue. Treatment options for DLBCL may include chemotherapy, radiation therapy, and targeted therapy, as well as stem cell transplantation in some cases. The prognosis for DLBCL depends on various factors, including the stage of the cancer at diagnosis and the patient's overall health.

Iris neoplasms refer to abnormal growths or tumors that develop in the iris, which is the colored part of the eye. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Benign iris neoplasms are relatively rare and usually do not cause any symptoms. However, they can sometimes cause changes in the shape or color of the iris, which can be noticed by an eye doctor during a routine eye exam. Malignant iris neoplasms, on the other hand, are more serious and can cause a variety of symptoms, including changes in vision, eye pain, and redness. If left untreated, they can spread to other parts of the eye and even to other parts of the body. Treatment for iris neoplasms depends on the type and size of the tumor, as well as the patient's overall health. Options may include observation, medication, laser therapy, or surgery. It is important to seek medical attention if you notice any changes in your vision or if you have any other symptoms that may be related to an iris neoplasm.

Postoperative complications are adverse events that occur after a surgical procedure. They can range from minor issues, such as bruising or discomfort, to more serious problems, such as infection, bleeding, or organ damage. Postoperative complications can occur for a variety of reasons, including surgical errors, anesthesia errors, infections, allergic reactions to medications, and underlying medical conditions. They can also be caused by factors such as poor nutrition, dehydration, and smoking. Postoperative complications can have serious consequences for patients, including prolonged hospital stays, additional surgeries, and even death. Therefore, it is important for healthcare providers to take steps to prevent postoperative complications and to promptly recognize and treat them if they do occur.

Ki-67 is a protein found in the nuclei of cells that are actively dividing. It is a useful marker for assessing the growth rate of tumors and is often used in conjunction with other markers to help diagnose and predict the behavior of cancer. The Ki-67 antigen is named after the Danish pathologist, Kai Erik Nielsen, who first described it in the 1980s. It is typically measured using immunohistochemistry, a technique that uses antibodies to detect specific proteins in tissue samples.

In the medical field, the term "carbon" typically refers to the chemical element with the atomic number 6, which is a vital component of all living organisms. Carbon is the building block of organic molecules, including proteins, carbohydrates, lipids, and nucleic acids, which are essential for the structure and function of cells and tissues. In medicine, carbon is also used in various diagnostic and therapeutic applications. For example, carbon-13 (13C) is a stable isotope of carbon that is used in metabolic studies to investigate the function of enzymes and pathways in the body. Carbon-14 (14C) is a radioactive isotope of carbon that is used in radiocarbon dating to determine the age of organic materials, including human remains. Additionally, carbon dioxide (CO2) is a gas that is produced by the body during respiration and is exhaled. It is also used in medical applications, such as in carbon dioxide laser therapy, which uses the energy of CO2 lasers to treat various medical conditions, including skin disorders, tumors, and eye diseases.

Prednisolone is a synthetic glucocorticoid hormone that is used in the medical field to treat a variety of conditions. It is a potent anti-inflammatory and immunosuppressive agent that is commonly used to treat inflammatory diseases such as rheumatoid arthritis, lupus, and psoriasis. It is also used to treat allergies, asthma, and other respiratory conditions, as well as to reduce swelling and inflammation in the body. In addition, prednisolone is used to treat certain types of cancer, such as lymphoma and leukemia, and to prevent rejection of transplanted organs. It is available in various forms, including tablets, injections, and eye drops, and is typically prescribed by a doctor or other healthcare professional.

Pituitary ACTH hypersecretion is a medical condition in which the pituitary gland produces excessive amounts of adrenocorticotropic hormone (ACTH). This can lead to an overproduction of cortisol, a hormone produced by the adrenal glands, which can cause a variety of symptoms and health problems. There are several potential causes of pituitary ACTH hypersecretion, including: * Cushing's disease: This is the most common cause of pituitary ACTH hypersecretion. It is caused by a benign tumor (adenoma) in the pituitary gland that produces excess ACTH. * Ectopic ACTH syndrome: This is a rare condition in which ACTH is produced by a tumor outside of the pituitary gland, such as in the lungs, thymus, or pancreas. * Primary pigmented nodular adrenocortical disease (PPNAD): This is a rare genetic disorder that causes the adrenal glands to produce excess ACTH. Symptoms of pituitary ACTH hypersecretion may include: * Weight gain, particularly around the abdomen * Fatigue * Muscle weakness * High blood pressure * High blood sugar * Osteoporosis * Thinning of the skin and easy bruising * Depression or irritability Treatment for pituitary ACTH hypersecretion depends on the underlying cause. In some cases, surgery to remove the tumor causing the excess ACTH production may be necessary. Medications may also be used to help control cortisol levels and manage symptoms. In some cases, radiation therapy may be used to shrink the tumor or control its growth.

Yttrium radioisotopes are radioactive isotopes of the element yttrium that are used in medical imaging and cancer treatment. Yttrium-90 (90Y) is a commonly used radioisotope in these applications. It is produced by bombarding a target with neutrons, and it emits beta particles that can be detected by imaging equipment. In medical imaging, 90Y is often used in conjunction with a radiopharmaceutical, which is a compound that contains 90Y and is designed to target specific cells or tissues in the body. For example, 90Y-labeled antibodies can be used to image and diagnose certain types of cancer, such as non-Hodgkin's lymphoma and multiple myeloma. The beta particles emitted by 90Y can also be used to destroy cancer cells through a process called radioimmunotherapy. In cancer treatment, 90Y is often used in conjunction with a radiopharmaceutical to deliver targeted radiation therapy to cancer cells. This can be particularly useful in cases where the cancer has spread to multiple sites in the body and is difficult to treat with traditional chemotherapy or radiation therapy. The radiopharmaceutical is designed to target the cancer cells specifically, minimizing damage to healthy cells and tissues.

Cholangiocarcinoma is a type of cancer that develops in the bile ducts, which are the tubes that carry bile from the liver to the small intestine. It is a rare but aggressive form of cancer that can occur in the liver, bile ducts in the liver, or the bile ducts outside the liver. Cholangiocarcinoma can be classified into two main types: intrahepatic cholangiocarcinoma (which occurs within the liver) and extrahepatic cholangiocarcinoma (which occurs outside the liver, in the bile ducts that connect the liver to the small intestine). Symptoms of cholangiocarcinoma may include jaundice (yellowing of the skin and eyes), abdominal pain, weight loss, fever, and fatigue. Diagnosis typically involves imaging tests such as ultrasound, CT scan, or MRI, as well as a biopsy to confirm the presence of cancer cells. Treatment for cholangiocarcinoma may include surgery, chemotherapy, radiation therapy, or a combination of these approaches. The prognosis for cholangiocarcinoma depends on several factors, including the stage of the cancer at diagnosis, the location of the tumor, and the patient's overall health.

Salivary gland neoplasms refer to tumors that develop in the salivary glands, which are responsible for producing saliva. These glands are located in the mouth, head, and neck, and include the parotid gland, submandibular gland, and sublingual gland. Salivary gland neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can affect any part of the salivary gland. Symptoms of salivary gland neoplasms may include a lump or swelling in the gland, difficulty swallowing or chewing, and pain or discomfort in the gland or surrounding area. Treatment for salivary gland neoplasms may include surgery, radiation therapy, or chemotherapy, depending on the type and stage of the tumor.

Kidney neoplasms refer to abnormal growths or tumors that develop in the kidneys. These tumors can be either benign (non-cancerous) or malignant (cancerous). Kidney neoplasms are also known as renal neoplasms or renal tumors. There are several types of kidney neoplasms, including: 1. Renal cell carcinoma (RCC): This is the most common type of kidney cancer and accounts for about 80-90% of all kidney neoplasms. 2. Wilms tumor: This is a type of kidney cancer that is most common in children. 3. Angiomyolipoma: This is a benign tumor that is made up of fat, smooth muscle, and blood vessels. 4. Oncocytoma: This is a benign tumor that is made up of cells that resemble normal kidney cells. 5. Papillary renal cell carcinoma: This is a type of kidney cancer that is less common than RCC but has a better prognosis. 6. Clear cell renal cell carcinoma: This is a type of kidney cancer that is the most common in adults and has a poor prognosis. The diagnosis of kidney neoplasms typically involves imaging tests such as ultrasound, CT scan, or MRI, as well as a biopsy to confirm the type and stage of the tumor. Treatment options for kidney neoplasms depend on the type, size, and stage of the tumor, as well as the overall health of the patient. Treatment options may include surgery, radiation therapy, chemotherapy, or targeted therapy.

Wilms tumor, also known as nephroblastoma, is a type of cancer that affects the kidneys in children. It is the most common type of kidney cancer in children, accounting for about 90% of all kidney tumors in children. Wilms tumor usually occurs in children between the ages of 2 and 5, but it can occur at any age. The tumor is named after Dr. Max Wilms, a German pediatrician who first described the condition in 1899. Wilms tumor is a type of cancer that arises from immature cells in the kidneys, called nephroblasts. These cells have the potential to develop into different types of kidney cells, but in Wilms tumor, they become cancerous and start to grow uncontrollably. The symptoms of Wilms tumor can vary depending on the size and location of the tumor, as well as the extent to which it has spread. Some common symptoms include abdominal pain, swelling in the abdomen or legs, blood in the urine, and a mass or lump in the abdomen. In some cases, Wilms tumor may not cause any symptoms until it has grown quite large. Treatment for Wilms tumor typically involves surgery to remove the tumor, followed by chemotherapy and/or radiation therapy to kill any remaining cancer cells. The prognosis for Wilms tumor is generally very good, with the majority of children who are diagnosed with the disease being cured with treatment. However, the long-term effects of treatment, such as damage to the kidneys or other organs, can be significant.

Triazines are a class of organic compounds that contain a three-membered nitrogen ring. They are commonly used as herbicides, pesticides, and fungicides. In the medical field, triazines have been studied for their potential use in the treatment of various conditions, including cancer, viral infections, and inflammatory diseases. Some specific examples of triazines that have been studied for medical use include protriptyline, a tricyclic antidepressant, and terbinafine, an antifungal medication. However, it is important to note that the use of triazines in medicine is still in the experimental stage, and more research is needed to fully understand their potential therapeutic benefits and risks.

In the medical field, "Neoplasms, Experimental" refers to the study of neoplasms (abnormal growths of cells) in experimental settings, such as in laboratory animals or in vitro cell cultures. These studies are typically conducted to better understand the underlying mechanisms of neoplasms and to develop new treatments for cancer and other types of neoplastic diseases. Experimental neoplasms may be induced by various factors, including genetic mutations, exposure to carcinogens, or other forms of cellular stress. The results of these studies can provide valuable insights into the biology of neoplasms and help to identify potential targets for therapeutic intervention.

Camptothecin is a natural alkaloid compound that is derived from the Chinese tree Camptotheca acuminata. It has been used in the medical field as an anti-cancer drug due to its ability to inhibit the activity of topoisomerase I, an enzyme that is essential for DNA replication and repair. This inhibition leads to the formation of DNA double-strand breaks, which can cause cell death and prevent the growth and spread of cancer cells. Camptothecin and its derivatives have been used to treat various types of cancer, including ovarian, lung, and colorectal cancer. However, they can also cause significant side effects, such as nausea, vomiting, and diarrhea, and may interact with other medications.

Muscle neoplasms are abnormal growths or tumors that develop in the muscles of the body. They can be either benign (non-cancerous) or malignant (cancerous). Benign muscle neoplasms are usually slow-growing and do not spread to other parts of the body. They can cause symptoms such as pain, weakness, and swelling in the affected muscle. Examples of benign muscle neoplasms include fibromatosis, lipoma, and leiomyoma. Malignant muscle neoplasms, on the other hand, are more aggressive and can spread to other parts of the body. They can cause similar symptoms as benign muscle neoplasms, but they may also cause more serious complications such as difficulty moving, weight loss, and fatigue. Examples of malignant muscle neoplasms include rhabdomyosarcoma, leiomyosarcoma, and fibrosarcoma. Diagnosis of muscle neoplasms typically involves a combination of physical examination, imaging tests such as MRI or CT scans, and biopsy. Treatment options depend on the type, size, and location of the tumor, as well as the patient's overall health. They may include surgery, radiation therapy, chemotherapy, or a combination of these treatments.

Thiotepa is a chemotherapy drug that is used to treat certain types of cancer, including ovarian cancer, breast cancer, and lung cancer. It works by interfering with the growth and division of cancer cells, which can slow down or stop the growth of tumors. Thiotepa is usually given intravenously (into a vein) or as a solution that is injected directly into the tumor. It can also be given orally (by mouth) in some cases. Thiotepa can cause side effects, including nausea, vomiting, hair loss, and a low white blood cell count. It is important to follow your doctor's instructions carefully when taking thiotepa, as it can be toxic if not used properly.

Carcinoma, Mucoepidermoid is a type of cancer that originates in the mucus-producing cells of the salivary glands. It is a rare type of salivary gland cancer, accounting for about 10% of all salivary gland cancers. Mucoepidermoid carcinoma can occur in any of the salivary glands, but it is most commonly found in the parotid gland, which is located in front of the ear. The cancer cells in mucoepidermoid carcinoma can vary in appearance and function, which can affect the behavior and treatment of the cancer. Symptoms of mucoepidermoid carcinoma may include a lump or mass in the neck or mouth, difficulty swallowing, ear pain, and facial weakness. Diagnosis typically involves a combination of imaging tests, such as CT scans or MRI, and a biopsy of the affected tissue. Treatment for mucoepidermoid carcinoma may include surgery to remove the cancerous tissue, radiation therapy, and/or chemotherapy. The specific treatment plan will depend on the stage and location of the cancer, as well as the overall health of the patient.

Lacrimal apparatus diseases refer to a group of medical conditions that affect the tear drainage system of the eye. The tear drainage system, also known as the lacrimal apparatus, includes the lacrimal glands, lacrimal ducts, lacrimal sac, and nasolacrimal duct. These structures work together to produce and drain tears from the eye, keeping it moist and protected. Lacrimal apparatus diseases can be classified into two main categories: lacrimal gland diseases and lacrimal duct diseases. Lacrimal gland diseases include conditions such as dacryoadenitis (inflammation of the lacrimal gland), dacryocystitis (inflammation of the lacrimal sac), and dacryocystocele (protrusion of the lacrimal sac). Lacrimal duct diseases include conditions such as nasolacrimal duct obstruction (blockage of the nasolacrimal duct), which can cause tearing, discharge from the eye, and other symptoms. Lacrimal apparatus diseases can be treated with a variety of methods, including medications, punctal occlusion (plugging of the tear ducts), and surgery. The specific treatment approach depends on the underlying cause and severity of the condition. Early diagnosis and treatment are important to prevent complications and improve outcomes.

Razoxane, also known as hydroxyurea, is a medication used to treat certain types of cancer, including leukemia and lymphoma. It works by slowing the growth of cancer cells and preventing them from dividing and multiplying. Razoxane is usually given in combination with other chemotherapy drugs and is typically administered intravenously or orally. It can also be used to prevent or reduce the risk of blood clots in people who have had a heart attack or stroke.

Urination disorders, also known as urological disorders, refer to a range of conditions that affect the urinary system, including the kidneys, bladder, ureters, and urethra. These disorders can cause a variety of symptoms, such as difficulty starting or stopping urination, frequent or urgent need to urinate, pain or burning during urination, blood in the urine, and incontinence. Some common types of urination disorders include: 1. Overactive bladder (OAB): A condition characterized by an urgent need to urinate, often accompanied by a strong urge to go and difficulty delaying urination. 2. Urinary incontinence: A condition in which a person is unable to control the flow of urine, resulting in leakage. 3. Urinary tract infections (UTIs): Infections that affect the urinary tract, including the bladder, kidneys, ureters, and urethra. 4. Benign prostatic hyperplasia (BPH): A condition in which the prostate gland becomes enlarged, causing difficulty urinating. 5. Kidney stones: Hard mineral deposits that form in the kidneys and can cause pain and other symptoms. 6. Kidney failure: A condition in which the kidneys are unable to filter waste products from the blood, leading to a buildup of toxins in the body. 7. Urinary retention: A condition in which the bladder is unable to empty completely, leading to a feeling of fullness and discomfort. Treatment for urination disorders depends on the underlying cause and may include medications, lifestyle changes, and in some cases, surgery.

A Glomus Jugulare Tumor, also known as a Glomus Tumor or Glomus Jugulare, is a rare benign (non-cancerous) tumor that develops in the glomus body, which is a small, blood-filled structure located in the middle ear. The glomus body is responsible for regulating blood flow to the inner ear, and a tumor in this area can cause a variety of symptoms, including: * Headache * Ear pain * Hearing loss * Tinnitus (ringing in the ears) * Dizziness or vertigo * Swelling in the neck or face * Difficulty swallowing Glomus Jugulare Tumors are typically diagnosed using imaging tests such as MRI or CT scans, and treatment options may include surgery, radiation therapy, or a combination of both. It is important to note that while Glomus Jugulare Tumors are generally benign, they can cause significant symptoms and may require prompt medical attention.

Acromegaly is a rare hormonal disorder that occurs when the pituitary gland produces too much growth hormone (GH). This excess GH causes the body's tissues to grow abnormally, leading to a variety of physical and health problems. The most noticeable physical changes associated with acromegaly are the enlargement of the hands, feet, and facial features, particularly the nose, lips, and jaw. Other symptoms may include joint pain, thickening of the skin, excessive sweating, and sleep apnea. Acromegaly is typically diagnosed through a combination of physical examination, blood tests to measure GH levels, and imaging studies such as MRI or CT scans to visualize the pituitary gland. Treatment options for acromegaly may include surgery to remove the pituitary tumor, radiation therapy, and medications to lower GH levels. Early diagnosis and treatment are important to prevent complications and improve quality of life for individuals with acromegaly.

An adenoma is a benign (non-cancerous) tumor that develops from glandular cells. It is a type of neoplasm, which is an abnormal growth of cells. Adenomas can occur in various parts of the body, including the colon, rectum, breast, thyroid gland, and prostate gland. In the colon and rectum, adenomas are commonly referred to as polyps. They can vary in size and shape and may or may not cause symptoms. However, some adenomas can develop into cancer if left untreated, which is why they are often removed during a colonoscopy or other screening tests. In other parts of the body, adenomas may cause symptoms depending on their location and size. For example, an adenoma in the thyroid gland may cause a goiter, while an adenoma in the prostate gland may cause difficulty urinating. Treatment for adenomas depends on their size, location, and whether they are causing symptoms. Small adenomas may not require treatment, while larger ones may be removed through surgery or other procedures. In some cases, medication may be used to shrink the adenoma or prevent it from growing back.

The Epidermal Growth Factor Receptor (EGFR) is a type of cell surface receptor protein that is found on the surface of cells in the epidermis, as well as in other tissues throughout the body. The EGFR is a member of a family of receptors called receptor tyrosine kinases, which are involved in regulating cell growth, differentiation, and survival. When the EGFR binds to its ligand, a protein called epidermal growth factor (EGF), it triggers a cascade of intracellular signaling events that ultimately lead to the activation of various genes involved in cell growth and proliferation. This process is important for normal tissue growth and repair, but it can also contribute to the development of cancer when the EGFR is overactive or mutated. EGFR inhibitors are a class of drugs that are used to treat certain types of cancer, such as non-small cell lung cancer and head and neck cancer, by blocking the activity of the EGFR and preventing it from signaling downstream genes. These drugs can be used alone or in combination with other treatments, such as chemotherapy or radiation therapy.

In the medical field, "neoplasm seeding" refers to the process by which cancer cells break away from a primary tumor and spread to other parts of the body. This can occur through the bloodstream or lymphatic system, and is also known as metastasis. Neoplasm seeding is a serious complication of cancer, as it can lead to the development of new tumors in other organs, making the cancer more difficult to treat and potentially leading to a poor prognosis for the patient.

Necrosis is a type of cell death that occurs when cells in the body die due to injury, infection, or lack of oxygen and nutrients. In necrosis, the cells break down and release their contents into the surrounding tissue, leading to inflammation and tissue damage. Necrosis can occur in any part of the body and can be caused by a variety of factors, including trauma, infection, toxins, and certain diseases. It is different from apoptosis, which is a programmed cell death that occurs as part of normal development and tissue turnover. In the medical field, necrosis is often seen as a sign of tissue injury or disease, and it can be a serious condition if it affects vital organs or tissues. Treatment for necrosis depends on the underlying cause and may include medications, surgery, or other interventions to address the underlying condition and promote healing.

Uterine neoplasms refer to abnormal growths or tumors that develop in the uterus, which is the female reproductive organ responsible for carrying and nourishing a developing fetus during pregnancy. These neoplasms can be benign (non-cancerous) or malignant (cancerous) in nature. Benign uterine neoplasms include leiomyomas (fibroids), adenomyosis, and endometrial polyps. These conditions are relatively common and often do not require treatment unless they cause symptoms such as heavy bleeding, pain, or pressure on other organs. Malignant uterine neoplasms, on the other hand, are less common but more serious. The most common type of uterine cancer is endometrial cancer, which develops in the lining of the uterus. Other types of uterine cancer include uterine sarcomas, which are rare and aggressive tumors that develop in the muscle or connective tissue of the uterus. Diagnosis of uterine neoplasms typically involves a combination of physical examination, imaging studies such as ultrasound or MRI, and biopsy. Treatment options depend on the type, size, and location of the neoplasm, as well as the patient's overall health and age. Treatment may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Jaw diseases refer to a group of medical conditions that affect the jawbone, the muscles of the jaw, and the temporomandibular joint (TMJ). These conditions can cause pain, swelling, and difficulty chewing or speaking. Some common jaw diseases include: 1. Temporomandibular joint disorder (TMD): This is a group of conditions that affect the TMJ, which is the joint that connects the lower jaw to the skull. TMD can cause pain, stiffness, and limited movement of the jaw. 2. Periodontal disease: This is a bacterial infection that affects the gums and bone that support the teeth. If left untreated, periodontal disease can lead to tooth loss and damage to the jawbone. 3. Osteoarthritis: This is a degenerative joint disease that can affect the TMJ, causing pain, stiffness, and limited movement. 4. Osteomyelitis: This is an infection of the bone, which can affect the jawbone and cause pain, swelling, and fever. 5. Fibrous dysplasia: This is a rare bone disorder that can affect the jawbone, causing pain, swelling, and deformity. 6. Giant cell tumor: This is a rare tumor that can affect the jawbone, causing pain, swelling, and deformity. Treatment for jaw diseases depends on the specific condition and may include medications, physical therapy, braces, or surgery. It is important to seek medical attention if you experience persistent pain or difficulty chewing or speaking.

Liposarcoma is a type of cancer that arises from the adipose tissue, which is the fat-storing tissue in the body. It is the most common type of soft tissue sarcoma, accounting for about 15% of all sarcomas. Liposarcomas can occur in any part of the body, but they are most commonly found in the retroperitoneum (the space behind the abdominal wall), the thigh, and the trunk. Liposarcomas are classified into five subtypes based on their microscopic appearance and genetic features. The most common subtype is well-differentiated liposarcoma, which tends to grow slowly and has a good prognosis. The other subtypes include dedifferentiated liposarcoma, myxoid liposarcoma, pleomorphic liposarcoma, and liposarcoma with chondroid differentiation. The diagnosis of liposarcoma is typically made through a combination of physical examination, imaging studies (such as MRI or CT scans), and biopsy. Treatment for liposarcoma usually involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to kill any remaining cancer cells. The prognosis for liposarcoma depends on the subtype, the stage of the cancer at diagnosis, and the patient's overall health.

Thyroid neoplasms refer to abnormal growths or tumors in the thyroid gland, which is a butterfly-shaped gland located in the neck. These neoplasms can be either benign (non-cancerous) or malignant (cancerous). Thyroid neoplasms can occur in any part of the thyroid gland, but some areas are more prone to developing tumors than others. The most common type of thyroid neoplasm is a thyroid adenoma, which is a benign tumor that arises from the follicular cells of the thyroid gland. Other types of thyroid neoplasms include papillary thyroid carcinoma, follicular thyroid carcinoma, medullary thyroid carcinoma, and anaplastic thyroid carcinoma. Thyroid neoplasms can cause a variety of symptoms, depending on the size and location of the tumor, as well as whether it is benign or malignant. Some common symptoms include a lump or swelling in the neck, difficulty swallowing, hoarseness, and a rapid or irregular heartbeat. Diagnosis of thyroid neoplasms typically involves a combination of physical examination, imaging studies such as ultrasound or CT scan, and biopsy of the thyroid tissue. Treatment options for thyroid neoplasms depend on the type, size, and location of the tumor, as well as the patient's overall health and age. Treatment may include surgery, radiation therapy, or medication to manage symptoms or slow the growth of the tumor.

Tamoxifen is a medication that is primarily used to treat breast cancer in women. It works by blocking the effects of estrogen, a hormone that can stimulate the growth of breast cancer cells. Tamoxifen is often used as part of a combination therapy, along with other medications or surgery, to treat breast cancer. It can also be used to prevent breast cancer in women who are at high risk of developing the disease, such as those who have a family history of breast cancer or who have certain genetic mutations that increase their risk. Tamoxifen is usually taken orally in the form of tablets, and the dosage and duration of treatment will depend on the individual patient's needs and the type and stage of their breast cancer.

Voice disorders refer to a range of conditions that affect the production of sound by the vocal cords. These disorders can be caused by a variety of factors, including injury, infection, or structural abnormalities of the vocal cords or surrounding structures. Some common types of voice disorders include: 1. Hoarseness: A persistent or chronic hoarse voice, which can be caused by a variety of factors, including vocal cord nodules, polyps, or inflammation. 2. Stridor: A high-pitched whistling sound that occurs when air flows through a narrowed airway, which can be caused by vocal cord dysfunction, laryngomalacia, or other conditions. 3. Dysphonia: A difficulty or impairment in the production of speech, which can be caused by a variety of factors, including vocal cord paralysis, vocal cord paresis, or vocal cord dysfunction. 4. Vocal fatigue: A feeling of exhaustion or strain in the voice after speaking for a prolonged period of time, which can be caused by overuse, dehydration, or other factors. 5. Vocal cord paralysis: A condition in which one or both vocal cords do not move properly, which can be caused by injury, surgery, or other factors. 6. Vocal cord nodules: Small, benign growths on the vocal cords that can cause hoarseness or difficulty speaking. 7. Vocal cord polyps: Larger growths on the vocal cords that can cause hoarseness, difficulty speaking, or breathing problems. Treatment for voice disorders depends on the underlying cause and may include voice therapy, medication, surgery, or other interventions.

Carcinoma, Basal Cell is a type of skin cancer that originates from the basal cells, which are the cells that line the bottom layer of the epidermis, the outermost layer of the skin. It is the most common type of skin cancer and is usually slow-growing and non-aggressive. However, if left untreated, it can spread to other parts of the body and become more serious. The main risk factors for basal cell carcinoma include exposure to UV radiation from the sun or tanning beds, fair skin, and a history of skin cancer. Treatment options for basal cell carcinoma include surgery, radiation therapy, and topical medications.

Tracheal neoplasms refer to abnormal growths or tumors that develop in the trachea, which is the tube that carries air from the larynx to the lungs. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) in nature. Benign tracheal neoplasms are relatively rare and may include polyps, papillomas, and granulomas. These growths can cause symptoms such as difficulty breathing, hoarseness, and coughing, and may require surgical removal. Malignant tracheal neoplasms, on the other hand, are more common and can include squamous cell carcinoma, adenocarcinoma, and small cell carcinoma. These tumors can spread to other parts of the body and are typically more aggressive than benign neoplasms. Treatment options for malignant tracheal neoplasms may include surgery, radiation therapy, chemotherapy, and targeted therapy. Overall, tracheal neoplasms can have significant impact on a person's quality of life and may require prompt diagnosis and treatment to prevent complications and improve outcomes.

Nausea is a common sensation of uneasiness or discomfort in the upper stomach with an involuntary urge to vomit. It can be a symptom of various medical conditions, including gastrointestinal disorders, infections, pregnancy, and certain medications. In the medical field, nausea is often evaluated and treated by a healthcare provider to determine the underlying cause and provide appropriate treatment.

Conjunctival neoplasms refer to abnormal growths or tumors that develop on the conjunctiva, which is the thin, transparent membrane that covers the white part of the eye (sclera) and lines the inside of the eyelids. These neoplasms can be benign (non-cancerous) or malignant (cancerous) and can occur in various forms, including papillomas, fibromas, adenomas, and squamous cell carcinomas. Conjunctival neoplasms can cause a variety of symptoms, including redness, swelling, discharge, irritation, and changes in vision. They can also lead to complications such as ulceration, bleeding, and perforation of the conjunctiva or sclera. Diagnosis of conjunctival neoplasms typically involves a thorough eye examination, including a visual examination, a biomicroscopic examination, and a biopsy if necessary. Treatment options depend on the type, size, and location of the neoplasm, as well as the patient's overall health and preferences. Treatment options may include observation, surgical removal, cryotherapy, radiation therapy, or chemotherapy.

Quinazolines are a class of heterocyclic compounds that contain a six-membered ring with two nitrogen atoms and one oxygen atom. They are structurally similar to quinolines, but with an additional nitrogen atom in the ring. In the medical field, quinazolines have been used as a class of antimalarial drugs, such as chloroquine and hydroxychloroquine, which are used to treat and prevent malaria. They have also been used as antiviral agents, such as the antiretroviral drug efavirenz, which is used to treat HIV/AIDS. Quinazolines have also been studied for their potential use in treating other diseases, such as cancer, tuberculosis, and inflammatory diseases. Some quinazolines have been found to have anti-inflammatory and immunosuppressive properties, which may make them useful in treating autoimmune diseases.

In the medical field, "Neoplasms, Germ Cell and Embryonal" refers to a group of tumors that arise from cells that are derived from the germ cells or embryonic cells. Germ cells are the cells that give rise to eggs and sperm, while embryonic cells are the cells that give rise to all the different types of cells in the body during development. Neoplasms, Germ Cell and Embryonal tumors can occur in various parts of the body, including the brain, spinal cord, testes, ovaries, and other organs. These tumors can be either benign (non-cancerous) or malignant (cancerous). The diagnosis of a Neoplasms, Germ Cell and Embryonal tumor typically involves a combination of imaging studies, such as CT scans or MRI scans, and a biopsy to examine the tissue. Treatment options may include surgery, chemotherapy, radiation therapy, or a combination of these approaches, depending on the type and location of the tumor, as well as the patient's overall health.

Carcinoma, bronchogenic is a type of cancer that starts in the cells that line the airways of the lungs. These airways include the bronchi, which are the large tubes that carry air into and out of the lungs, and the bronchioles, which are smaller tubes that branch off from the bronchi. Carcinoma, bronchogenic is also known as lung cancer. There are several different types of lung cancer, including small cell lung cancer and non-small cell lung cancer. Carcinoma, bronchogenic is a type of non-small cell lung cancer. It is the most common type of lung cancer and is usually diagnosed at a later stage, when it has already spread to other parts of the body. Symptoms of carcinoma, bronchogenic may include a persistent cough, chest pain, shortness of breath, hoarseness, and coughing up blood. These symptoms may be caused by the cancer itself or by the body's response to the cancer. Treatment for carcinoma, bronchogenic may include surgery, radiation therapy, chemotherapy, or a combination of these treatments. The best treatment option will depend on the stage and location of the cancer, as well as the overall health of the person.

Leiomyosarcoma is a type of cancer that arises from smooth muscle cells, which are found in various parts of the body, including the uterus, uterus lining, and blood vessels. It is a rare and aggressive form of cancer that can occur in both men and women, although it is more common in women. Leiomyosarcomas can develop in any part of the body where smooth muscle tissue is present, but they are most commonly found in the uterus, uterus lining, and blood vessels. Other common sites of occurrence include the gastrointestinal tract, retroperitoneum (the space behind the abdominal wall), and the skin. The symptoms of leiomyosarcoma can vary depending on the location of the tumor and its size. In some cases, there may be no symptoms at all, while in others, symptoms may include pain, swelling, and a mass or lump in the affected area. In some cases, leiomyosarcomas can spread to other parts of the body, leading to symptoms such as fatigue, weight loss, and weakness. Treatment for leiomyosarcoma typically involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to kill any remaining cancer cells. The prognosis for leiomyosarcoma depends on several factors, including the location and size of the tumor, the stage of the cancer at the time of diagnosis, and the patient's overall health.

Teniposide is a chemotherapy drug that is used to treat certain types of cancer, including non-Hodgkin's lymphoma, testicular cancer, and ovarian cancer. It works by interfering with the normal functioning of cancer cells, which can cause them to die or stop growing. Teniposide is usually given intravenously, and the dosage and duration of treatment will depend on the type and stage of cancer being treated, as well as the patient's overall health. Side effects of teniposide can include nausea, vomiting, hair loss, fatigue, and an increased risk of infection.

Chlorambucil is an alkylating chemotherapy drug that is used to treat various types of cancer, including chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma. It works by interfering with the ability of cancer cells to divide and grow, ultimately leading to their death. Chlorambucil is usually given orally, and its side effects can include nausea, vomiting, hair loss, and a decreased ability to fight infections. It is important to note that Chlorambucil can also cause long-term side effects, such as an increased risk of developing other types of cancer, so it is important to carefully weigh the potential benefits and risks before starting treatment.

Neutropenia is a medical condition characterized by a low number of neutrophils, which are a type of white blood cell that plays a crucial role in the body's immune system. Neutrophils are responsible for fighting off infections and are a key component of the body's defense against bacterial, viral, and fungal infections. Neutropenia is typically defined as a neutrophil count of less than 1,500 cells per microliter (µL) of blood. However, the normal range of neutrophil counts can vary depending on the laboratory and the individual's age and sex. Neutropenia can be caused by a variety of factors, including certain medications, infections, autoimmune disorders, and cancer treatments such as chemotherapy and radiation therapy. It can also be a symptom of other medical conditions, such as bone marrow disorders, genetic disorders, and nutritional deficiencies. Neutropenia can increase the risk of infections, as the body has fewer neutrophils to fight off pathogens. Symptoms of neutropenia may include fever, chills, fatigue, and sore throat. Treatment for neutropenia depends on the underlying cause and may include medications to stimulate the production of neutrophils, antibiotics to treat infections, or changes to the individual's medications or treatment plan.

Optic Nerve Glioma is a rare type of tumor that develops in the optic nerve, which is responsible for transmitting visual information from the eye to the brain. It is most commonly found in children and young adults, and is usually benign (non-cancerous). However, in some cases, it can be malignant (cancerous). The symptoms of Optic Nerve Glioma may include vision loss, eye pain, and changes in the appearance of the eye. Treatment options for Optic Nerve Glioma may include surgery, radiation therapy, and chemotherapy.

Esophageal stenosis is a medical condition in which the esophagus, the tube that carries food from the mouth to the stomach, becomes narrowed or blocked. This can occur due to a variety of factors, including injury, infection, inflammation, or scarring. Esophageal stenosis can cause difficulty swallowing, chest pain, and other symptoms, and may require medical treatment to manage. In severe cases, surgery may be necessary to remove the blockage or repair the damaged tissue.

Sigmoid neoplasms refer to tumors that develop in the sigmoid colon, which is the lower part of the large intestine. These tumors can be either benign or malignant, and they are typically classified as adenomas or adenocarcinomas. Adenomas are non-cancerous growths that arise from the lining cells of the colon. They are usually small and slow-growing, but in some cases, they can develop into cancer over time. Adenocarcinomas, on the other hand, are cancerous tumors that develop from the lining cells of the colon. They can be either localized or have spread to other parts of the body. Sigmoid neoplasms can cause a variety of symptoms, including abdominal pain, changes in bowel habits, rectal bleeding, and weight loss. Diagnosis typically involves a combination of physical examination, imaging studies, and biopsy. Treatment for sigmoid neoplasms depends on the type and stage of the tumor. Benign tumors may be removed through surgery, while malignant tumors may require a combination of surgery, chemotherapy, and radiation therapy. Early detection and treatment are important for improving outcomes and reducing the risk of complications.

Lymphoma, B-Cell is a type of cancer that affects the B cells, which are a type of white blood cell that plays a crucial role in the immune system. B cells are responsible for producing antibodies that help the body fight off infections and diseases. In lymphoma, B cells grow and divide uncontrollably, forming tumors in the lymph nodes, bone marrow, and other parts of the body. There are several subtypes of B-cell lymphoma, including diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, and chronic lymphocytic leukemia (CLL). The symptoms of B-cell lymphoma can vary depending on the subtype and the location of the tumors, but may include swollen lymph nodes, fatigue, fever, night sweats, and weight loss. Treatment for B-cell lymphoma typically involves a combination of chemotherapy, radiation therapy, and targeted therapies. The specific treatment plan will depend on the subtype of lymphoma, the stage of the disease, and the overall health of the patient. In some cases, a stem cell transplant may also be recommended.

Leuprolide is a medication that is used to treat various conditions related to the endocrine system, particularly in men. It is a synthetic version of the hormone luteinizing hormone-releasing hormone (LHRH), which is produced by the hypothalamus and regulates the production of other hormones in the body. Leuprolide is commonly used to treat prostate cancer, uterine fibroids, and endometriosis. It works by blocking the production of testosterone, which can help slow the growth of prostate cancer cells and reduce the size of uterine fibroids. It can also be used to treat precocious puberty in children. Leuprolide is usually administered as an injection, either under the skin or into a muscle. The dosage and frequency of the injections will depend on the specific condition being treated and the individual patient's response to the medication. Common side effects of leuprolide include hot flashes, decreased sex drive, breast tenderness, and injection site reactions.

Meningeal carcinomatosis is a condition in which cancer cells spread to the meninges, the protective membranes that surround the brain and spinal cord. These cancer cells can cause inflammation and damage to the meninges, leading to a variety of symptoms such as headache, nausea, vomiting, and changes in mental status. Meningeal carcinomatosis can occur in people with cancer that has spread to other parts of the body, such as the lungs, breast, or prostate. It can also occur in people with primary brain tumors, such as glioblastoma multiforme. Treatment for meningeal carcinomatosis may include chemotherapy, radiation therapy, and surgery to remove any tumors that are present. However, the prognosis for people with this condition is generally poor, as the cancer cells are difficult to treat and can quickly spread throughout the brain and spinal cord.

Proto-oncogene proteins c-bcl-2 are a family of proteins that play a role in regulating cell survival and apoptosis (programmed cell death). They are encoded by the bcl-2 gene, which is located on chromosome 18 in humans. The c-bcl-2 protein is a member of the Bcl-2 family of proteins, which are involved in regulating the balance between cell survival and death. The c-bcl-2 protein is a homodimer, meaning that it forms a pair of identical protein molecules that interact with each other. It is primarily found in the cytoplasm of cells, but it can also be found in the nucleus. The c-bcl-2 protein is thought to function as an anti-apoptotic protein, meaning that it inhibits the process of programmed cell death. It does this by preventing the release of cytochrome c from the mitochondria, which is a key step in the activation of the apoptotic pathway. In addition, the c-bcl-2 protein can also promote cell survival by inhibiting the activity of pro-apoptotic proteins. Abnormal expression of the c-bcl-2 protein has been implicated in the development of various types of cancer, including lymphoma, leukemia, and ovarian cancer. In these cases, overexpression of the c-bcl-2 protein can lead to increased cell survival and resistance to apoptosis, which can contribute to the growth and progression of cancer.

Maxillary neoplasms refer to tumors or abnormal growths that develop in the maxillary region of the face, which includes the upper jawbone (maxilla) and the surrounding soft tissues. These neoplasms can be benign (non-cancerous) or malignant (cancerous) in nature. Some common types of maxillary neoplasms include: 1. Odontogenic tumors: These are tumors that develop from the cells that give rise to teeth, such as ameloblastomas, odontomas, and dentigerous cysts. 2. Benign tumors: These include lipomas, fibromas, and hemangiomas. 3. Malignant tumors: These include squamous cell carcinomas, adenoid cystic carcinomas, and mucoepidermoid carcinomas. Maxillary neoplasms can cause a variety of symptoms, depending on their location and size. These may include pain, swelling, difficulty chewing or swallowing, changes in facial appearance, and dental problems. Treatment options for maxillary neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Indium radioisotopes are radioactive isotopes of the element indium that are used in medical imaging and therapy. These isotopes emit radiation that can be detected by medical imaging equipment, such as single-photon emission computed tomography (SPECT) or positron emission tomography (PET) scanners. Indium radioisotopes are used in a variety of medical applications, including: 1. Diagnostic imaging: Indium-111 is commonly used in diagnostic imaging to detect infections, tumors, and other abnormalities in the body. It is often used in conjunction with antibodies or other targeting agents to help locate specific cells or tissues. 2. Radiation therapy: Indium-111 is also used in radiation therapy to treat certain types of cancer. It is administered to the patient in the form of a radioactive compound that is taken up by cancer cells, where it emits radiation that damages the cancer cells and slows their growth. Overall, indium radioisotopes play an important role in medical imaging and therapy, allowing doctors to diagnose and treat a wide range of conditions with greater accuracy and effectiveness.

Bromine radioisotopes are radioactive isotopes of the element bromine that are used in medical imaging and treatment. These isotopes are typically produced in a nuclear reactor or cyclotron and are then used in various medical applications, such as: 1. Diagnostic Imaging: Bromine radioisotopes are used in nuclear medicine to image the body's organs and tissues. For example, bromine-75 is used to image the thyroid gland, while bromine-82 is used to image the heart. 2. Cancer Treatment: Bromine radioisotopes are also used in cancer treatment, particularly in targeted radionuclide therapy. In this approach, a radioactive isotope is attached to a molecule that selectively targets cancer cells, allowing the radiation to be delivered directly to the tumor while minimizing damage to healthy tissue. Some common bromine radioisotopes used in medical applications include bromine-75, bromine-76, bromine-77, bromine-78, bromine-80, bromine-81, bromine-82, and bromine-84.

Fluorine radioisotopes are radioactive isotopes of the element fluorine that are used in medical imaging and treatment. These isotopes are typically produced in a cyclotron or other particle accelerator and are then introduced into the body, where they can be detected and imaged using specialized equipment. Fluorine radioisotopes are used in a variety of medical applications, including: 1. Positron emission tomography (PET) scans: Fluorine-18 is a commonly used radioisotope in PET scans, which are used to image the body's metabolism and assess the function of organs such as the brain, heart, and lungs. 2. Fluoride therapy: Fluorine-18 is also used in fluoride therapy, which is a treatment for osteoporosis and other bone diseases. In this treatment, patients are given a solution containing fluorine-18, which is absorbed by the bones and helps to strengthen them. 3. Radiosynovectomy: Fluorine-18 is also used in radiosynovectomy, a treatment for rheumatoid arthritis. In this treatment, a solution containing fluorine-18 is injected into the affected joint, where it is absorbed by the inflamed synovial tissue and destroys it. Fluorine radioisotopes are generally considered safe when used in medical applications, but they can be harmful if they are ingested or inhaled in large quantities. As a result, special precautions are taken to ensure that patients are exposed to minimal amounts of these isotopes during medical procedures.

A plasmacytoma is a type of cancer that arises from plasma cells, which are a type of white blood cell that produces antibodies. Plasmacytomas are typically found in the bone marrow, but they can also occur in other tissues, such as the lymph nodes, spleen, and soft tissues. There are two main types of plasmacytomas: solitary plasmacytoma and multiple myeloma. Solitary plasmacytoma is a single tumor that arises from a single plasma cell, while multiple myeloma is a more aggressive form of the disease that involves the proliferation of multiple plasma cells in the bone marrow. Plasmacytomas can cause a variety of symptoms, depending on the location and size of the tumor. Some common symptoms include bone pain, fatigue, weakness, and anemia. Treatment for plasmacytomas typically involves chemotherapy, radiation therapy, or a combination of both. In some cases, a stem cell transplant may also be recommended.

Uveal neoplasms refer to tumors that develop in the uvea, which is the middle layer of the eye that includes the iris, ciliary body, and choroid. These tumors can be either benign or malignant and can cause a variety of symptoms, including changes in vision, eye pain, and redness. Uveal neoplasms can be challenging to diagnose and treat, as they can grow and spread quickly and may require surgery, radiation therapy, or chemotherapy. Some common types of uveal neoplasms include iris melanoma, choroidal melanoma, and ciliary body melanoma.

Melphalan is a chemotherapy drug that is used to treat various types of cancer, including multiple myeloma, ovarian cancer, and breast cancer. It works by interfering with the production of DNA in cancer cells, which prevents them from dividing and growing. Melphalan is usually given intravenously or orally, and its side effects can include nausea, vomiting, hair loss, fatigue, and an increased risk of infection. It is important to note that Melphalan can be toxic to healthy cells as well, so it is typically used in combination with other medications to minimize side effects and increase its effectiveness.

In the medical field, organometallic compounds are compounds that contain a metal atom bonded to a carbon atom of an organic molecule. These compounds have a wide range of applications in medicine, including as drugs, diagnostic agents, and catalysts for various chemical reactions. One example of an organometallic compound used in medicine is cisplatin, which is a chemotherapy drug used to treat various types of cancer. Cisplatin contains a platinum atom bonded to two carbon atoms from organic molecules, and its mechanism of action involves binding to DNA and inhibiting its replication. Another example is ferrocene, which is an organometallic compound containing a ferrocene moiety. Ferrocene has been studied for its potential as a treatment for various diseases, including cancer and Alzheimer's disease, due to its ability to modulate cellular signaling pathways. Overall, organometallic compounds have a significant impact on the medical field, and ongoing research is exploring their potential for new therapeutic applications.

Rib fractures are breaks or cracks in one or more of the 12 pairs of ribs that make up the rib cage. They can occur as a result of direct trauma, such as a car accident or a fall, or from indirect trauma, such as a sports injury or a coughing fit. Rib fractures can be classified as either stable or unstable. Stable fractures involve only a crack in the bone, while unstable fractures involve a complete break or displacement of the bone. Stable fractures typically heal on their own within a few weeks to a few months, while unstable fractures may require medical intervention, such as surgery or casting, to promote healing and prevent complications. Symptoms of rib fractures may include pain, swelling, bruising, difficulty breathing, and a limited ability to move the affected area. Treatment for rib fractures may involve pain management, rest, and physical therapy to promote healing and prevent complications such as pneumonia or deep vein thrombosis. In severe cases, surgery may be necessary to repair or stabilize the fracture.

Hypopituitarism is a medical condition in which the pituitary gland, a small gland located at the base of the brain, fails to produce one or more of its hormones or does not produce them in sufficient quantities. The pituitary gland is responsible for producing hormones that regulate various bodily functions, including growth, metabolism, reproduction, and stress response. Hypopituitarism can be caused by a variety of factors, including tumors, head injuries, infections, radiation therapy, and certain medications. Symptoms of hypopituitarism can vary depending on which hormones are affected, but may include fatigue, weight loss, decreased appetite, cold intolerance, decreased sexual desire, infertility, and mood changes. Treatment for hypopituitarism typically involves hormone replacement therapy to replace the hormones that are not being produced by the pituitary gland. The specific hormones that need to be replaced will depend on which hormones are affected and the severity of the deficiency. In some cases, surgery or radiation therapy may be necessary to treat the underlying cause of the hypopituitarism.

Colorectal neoplasms refer to abnormal growths or tumors that develop in the colon or rectum. These growths can be either benign (non-cancerous) or malignant (cancerous). Colorectal neoplasms can be further classified into polyps, adenomas, and carcinomas. Polyps are non-cancerous growths that typically arise from the inner lining of the colon or rectum. Adenomas are a type of polyp that have the potential to become cancerous if left untreated. Carcinomas, on the other hand, are cancerous tumors that can invade nearby tissues and spread to other parts of the body. Colorectal neoplasms are a common health concern, and regular screening is recommended for individuals at high risk, such as those with a family history of colorectal cancer or those over the age of 50. Early detection and treatment of colorectal neoplasms can significantly improve outcomes and reduce the risk of complications.

Prednimustine is a chemotherapy drug that is used to treat various types of cancer, including non-Hodgkin's lymphoma, breast cancer, and testicular cancer. It is a prodrug that is converted into the active form, mustine, in the body. Prednimustine is usually given intravenously or orally, and its side effects can include nausea, vomiting, hair loss, and an increased risk of infection. It is important to note that the use of prednimustine may cause serious side effects, and it should only be used under the supervision of a qualified healthcare professional.

Fibrosarcoma is a type of cancer that arises from the fibroblasts, which are cells that produce connective tissue in the body. It is a rare and aggressive form of cancer that typically affects the skin, but can also occur in other parts of the body such as the muscles, tendons, and soft tissues. Fibrosarcoma usually presents as a hard, painless mass that grows slowly over time. It can also cause swelling, redness, and warmth in the affected area. In some cases, fibrosarcoma can spread to other parts of the body through the bloodstream or lymphatic system. Treatment for fibrosarcoma typically involves surgery to remove the tumor, followed by radiation therapy or chemotherapy to kill any remaining cancer cells. In some cases, targeted therapy or immunotherapy may also be used. The prognosis for fibrosarcoma depends on the size and location of the tumor, as well as the patient's overall health and response to treatment.

Gastrointestinal (GI) diseases refer to conditions that affect the digestive system, which includes the esophagus, stomach, small intestine, large intestine, rectum, and anus. These diseases can range from minor to severe and can affect any part of the digestive system. Some common examples of gastrointestinal diseases include: 1. Gastroesophageal reflux disease (GERD): A condition in which stomach acid flows back up into the esophagus, causing heartburn and other symptoms. 2. Peptic ulcers: Sores that develop in the lining of the stomach or duodenum, often caused by the bacteria Helicobacter pylori. 3. Inflammatory bowel disease (IBD): A group of chronic inflammatory conditions that affect the digestive tract, including Crohn's disease and ulcerative colitis. 4. Irritable bowel syndrome (IBS): A condition characterized by abdominal pain, bloating, and changes in bowel habits that are not related to a structural problem in the digestive system. 5. Celiac disease: An autoimmune disorder in which the body reacts to gluten, a protein found in wheat, barley, and rye. 6. Diverticulitis: An inflammation of small pouches in the wall of the colon. 7. Colorectal cancer: A type of cancer that starts in the colon or rectum. 8. Gastrointestinal infections: Infections caused by bacteria, viruses, or parasites that affect the digestive system. These are just a few examples of the many gastrointestinal diseases that can affect people. Treatment for these conditions can vary depending on the specific disease and its severity.

Cytarabine, also known as cytosine arabinoside, is an antineoplastic medication used to treat various types of cancer, including acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and non-Hodgkin's lymphoma. It works by inhibiting the growth and division of cancer cells, thereby slowing or stopping their growth and spread. Cytarabine is typically administered intravenously or intramuscularly, and its dosage and duration of treatment depend on the type and stage of cancer being treated, as well as the patient's overall health. Common side effects of cytarabine include nausea, vomiting, fatigue, fever, and low blood cell counts, which can increase the risk of infection and bleeding. It is important to note that cytarabine is a chemotherapy drug and can cause serious side effects, so it is typically administered under the supervision of a healthcare professional in a hospital or clinic setting.

Mitomycins are a group of chemotherapy drugs that are derived from Streptomyces bacteria. They are classified as alkylating agents, which means that they work by damaging the DNA of cancer cells, preventing them from dividing and growing. Mitomycin is used to treat a variety of cancers, including bladder cancer, head and neck cancer, and cervical cancer. It is usually given intravenously or as a solution that is injected directly into the tumor. Mitomycin can cause side effects such as nausea, vomiting, diarrhea, and hair loss. It can also increase the risk of infection and bleeding.

Taste disorders refer to conditions that affect an individual's ability to perceive and enjoy the basic tastes of sweet, sour, salty, bitter, and umami. These disorders can be caused by a variety of factors, including physical damage to the taste buds, certain medications, infections, and neurological disorders. Taste disorders can manifest in different ways, such as a complete loss of taste, a reduced ability to taste certain tastes, or a distorted perception of taste. These disorders can have a significant impact on an individual's quality of life, as they may affect their ability to enjoy food and drink, and may also lead to nutritional deficiencies if certain tastes are not detected. Diagnosis of taste disorders typically involves a physical examination and a series of tests to assess an individual's ability to taste. Treatment options may include medication to address underlying causes, dietary changes, and in some cases, surgery to repair physical damage to the taste buds.

Vomiting is a medical condition characterized by the involuntary and forceful expulsion of the contents of the stomach through the mouth. It is also known as emesis or retching. Vomiting can be a symptom of a variety of medical conditions, including infections, digestive disorders, pregnancy, and certain medications. It can also be a response to toxins, such as those found in certain foods or chemicals. In severe cases, vomiting can lead to dehydration, electrolyte imbalances, and other complications. Treatment for vomiting depends on the underlying cause and may include medications, changes in diet and fluid intake, or other interventions.

Neoplasm proteins are proteins that are produced by cancer cells. These proteins are often abnormal and can contribute to the growth and spread of cancer. They can be detected in the blood or other body fluids, and their presence can be used as a diagnostic tool for cancer. Some neoplasm proteins are also being studied as potential targets for cancer treatment.

In the medical field, pain is defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Pain is a complex phenomenon that involves both physical and emotional components, and it can be caused by a variety of factors, including injury, illness, inflammation, and nerve damage. Pain can be acute or chronic, and it can be localized to a specific area of the body or can affect the entire body. Acute pain is typically short-lived and is a normal response to injury or illness. Chronic pain, on the other hand, persists for more than three months and can be caused by a variety of factors, including nerve damage, inflammation, and psychological factors. In the medical field, pain is typically assessed using a pain scale, such as the Visual Analog Scale (VAS), which measures pain intensity on a scale of 0 to 10. Treatment for pain depends on the underlying cause and can include medications, physical therapy, and other interventions.

Neuroblastoma is a type of cancer that develops from immature nerve cells, called neuroblasts, in the sympathetic nervous system. It is most commonly found in children, although it can also occur in adults. Neuroblastoma can occur anywhere in the body where neuroblasts are present, but it most often affects the adrenal glands, the neck, and the chest. The symptoms of neuroblastoma can vary depending on the location and size of the tumor, but they may include abdominal pain, swelling, and a lump or mass in the abdomen or neck. Treatment for neuroblastoma typically involves a combination of surgery, chemotherapy, radiation therapy, and stem cell transplantation.

Hoarseness, also known as dysphonia, is a condition characterized by a change in the quality or pitch of one's voice. It can be caused by a variety of factors, including inflammation or irritation of the vocal cords, injury or damage to the vocal cords, or problems with the nerves or muscles that control the vocal cords. In the medical field, hoarseness is often evaluated by a speech-language pathologist or an otolaryngologist (ear, nose, and throat doctor). Treatment for hoarseness depends on the underlying cause and may include medications, voice therapy, or surgery. In some cases, hoarseness may be a sign of a more serious underlying condition, such as cancer, and prompt medical attention is necessary.

Lymphedema is a condition characterized by the swelling of the body's tissues due to the accumulation of lymph fluid. The lymphatic system is responsible for draining excess fluid from the body's tissues, and when it is unable to function properly, fluid can build up and cause swelling. Lymphedema can occur in any part of the body, but it is most commonly seen in the arms, legs, and trunk. It can be caused by a variety of factors, including surgery, radiation therapy, infections, and genetic disorders. Lymphedema can be mild, moderate, or severe, and it can be chronic or temporary. Treatment for lymphedema typically involves compression therapy, exercise, and lymphatic massage. In severe cases, surgery may be necessary to remove excess fluid or to reconstruct damaged lymphatic vessels.

D50 in medicine is the half-maximal dose: the dose that produces 50% of the maximum response. It may specifically refer to the radiation dose required to achieve a 50% tumor control probability. LD50, is the dose required to kill half the members of a tested population after a specified test duration. H Gregerson; S Lindkaer Jensen; F Moody (1996). Essentials of Experimental Surgery: Gastroenterology. p. 19-3. ISBN 3-7186-5496-2. Lawrence S. Chin; William F. Regine (2010). Principles and Practice of Stereotactic Radiosurgery. p. 636. ISBN 978-0-387-71070-9. v t e (Radiation therapy, All stub articles, Medical treatment stubs ...
... is a type of radiation therapy used to treat eye tumors. A thin piece of metal (usually gold) with ... Plaque radiotherapy entry in the public domain NCI Dictionary of Cancer Terms This article incorporates public domain material ... Sagerman, Robert H.; Alberti, W. (2003-01-29). Radiotherapy of intraocular and orbital tumors. Springer. pp. 40-. ISBN 978-3- ...
List of civilian radiation accidents 1996 San Juan de Dios radiotherapy accident Clinic of Zaragoza radiotherapy accident "The ... A radiotherapy accident in Columbus, Ohio, also known as the Riverside radiation case, occurred as the result of an incorrectly ... Valentin, J (2000). "Case histories of major accidental exposures in radiotherapy". Annals of the ICRP. SAGE Publications. 30 ( ...
Many classifications are applied to radiotherapy. Teletherapy is the first of four classes of radiotherapy, as grouped by ... In contrast to brachytherapy (sealed source radiotherapy) and unsealed source radiotherapy, in which the radiation source is ... Each radiotherapy beam is composed of one type of particle which is intended for treatment, though most beams contain some ... Radiotherapy beams are classified by the particle they are intended to deliver. photons x-rays gamma rays electrons protons ...
Radiotherapy & Oncology is a peer-reviewed medical journal in the field of radiation oncology. Commonly referred to as "The ... Green Journal", it is published by Elsevier on behalf of the European Society for Radiation Oncology (ESTRO). "Radiotherapy & ...
... (WBRT) has been reported to increase the risk of cognitive decline. WBRT is sometimes used along with ... Whole brain radiotherapy (WBRT) is a palliative option for patients with brain metastases that alleviates symptoms, decreases ... "Whole-Brain Radiotherapy: Risks Worth Benefit?". Medscape.com. Retrieved August 20, 2015. Garsa, Adam; Jang, Julie K.; Baxi, ... McTyre, E; Scott, J; Chinnaiyan, P (2013). "Whole brain radiotherapy for brain metastasis". Surg Neurol Int. 4 (5): S236-44. ...
... , also known as targeted IORT, is a technique of giving radiotherapy to the tissues ... July 2010). "Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an ... February 2014). "Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year ... Adjuvant radiotherapy is necessary if breast cancer is treated by removing only the cancerous lump with a rim of surrounding ...
The radiotherapy unit was repaired without following the correct instructions. The unit, in service 14 years at the time of the ... The 1990 Clinic of Zaragoza radiotherapy accident was a radiological accident that occurred from 10 to 20 December 1990, at ... All of the injured were cancer patients receiving external beam radiotherapy. On 7 December 1990, a technician performed ...
The Institute of Radiotherapy and Nuclear Medicine (Urdu: جوہری طبی اور شعاعي علاج کا ادارہ, or IRNUM) is located at Khyber ... Oncology and Radiotherapy "Medical". PAEC. Retrieved June 11, 2020. "Medical Centres". PAEC. "institute of radiotheraphy and ... Radiotherapy Department Nuclear Medicine Department Pathology Department Maintenance Department Nuclear medicine in Pakistan ...
... this is called hypofractionated radiotherapy. Although the dose per fraction is higher than standard radiotherapy, the total ... This is an experimental form of intensity-modulated radiotherapy where higher X-ray dosages are used in fewer fractions ( ... "A trial comparing different ways of giving radiotherapy for prostate cancer (CHHIP)". 2015-03-17. UKCRN Database:Conventional ... or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer Archived September 27, 2007, at the Wayback ...
The side effects of radiotherapy on fertility are a growing concern to patients undergoing radiotherapy as cancer treatments. ... A significant issue associated with childhood radiotherapy includes infertility. Prepubescent males who experience radiotherapy ... Where the radiotherapy is directed is important as IR to the pelvis will affect the ovary and uterus or testis. Whereas cranial ... Radiotherapy is essential for certain cancer treatments and often is the first point of call for patients. Radiation can be ...
Nuclear medicine and Radiotherapy support. Thematic health programme. Radiotherapy Clinical application of radiosensitizers in ... Randomized clinical trial of radiotherapy combined with Mitomycin-C. Randomized Multi Center study of radiotherapy in the ... "nuclear medicine oncology & radiotherapy institute (nori), islamabad". icpsr. Retrieved 25 January 2014. Official website v t e ... Nuclear Medicine, Oncology and Radiotherapy Institute (NORI) is the 7th Cancer hospital and research centre; established by ...
"Karachi Institute of Radiotherapy & Nuclear Medicine (KIRAN)". Medical Review. July 2016. Retrieved December 25, 2016. Anjum ( ... The Karachi Institute of Radiotherapy and Nuclear Medicine (KIRAN) is a cancer hospital in Karachi, Pakistan under the ... KIRAN was initially planned to have state of the art radiotherapy facilities. Subsequently, oncology and chemotherapy sectors ...
The radiotherapy accident in Costa Rica occurred with the Alcyon II radiotherapy unit at San Juan de Dios Hospital in San José ... It was related to a cobalt-60 source that was being used for radiotherapy in 1996. An accidental overexposure of radiotherapy ... "CRC Daily: Costa Rica's 1996 radiotherapy tragedy". costaricadaily.substack.com. Retrieved 2021-01-05. 9°55′57″N 84°5′5″W /  ... Goiânia accident 1962 Mexico City radiation accident List of civilian radiation accidents Radiotherapy accident in Zaragoza X- ...
The Institute of Nuclear Medicine, Oncology and Radiotherapy (Urdu: جوہری طبی رسولی اور شعاعي علاج کا ادارہ, or INOR) is ... Ayub Teaching Hospital Pakistan Atomic Energy Commission Institute of Radiotherapy and Nuclear Medicine Pakistan Atomic Energy ...
"Radiotherapy". Patient UK. Archived from the original on 9 July 2017. Last Checked: 23 December 2015 Hill R, Healy B, Holloway ... is a growing specialty in wealthy countries and the major forms of human treatment such as surgery and radiotherapy may be ... radiotherapy, chemotherapy". Journal of Neurology, Neurosurgery, and Psychiatry. 75 (Suppl 2): ii24-30. doi:10.1136/jnnp. ...
... radiotherapy; other courses), the establishment integrates the Doctoral School of Oncology, Biology, Medicine, Health (and its ...
Radiotherapy is used when drug treatment is failing to control the pain of a growing tumor, such as in bone metastasis (most ... Hoskin PJ (2008). "Radiotherapy". In Sykes N, Bennett MI, Yuan CS (eds.). Clinical pain management: Cancer pain (2nd ed.). ...
Radiotherapy is used when drug treatment is failing to control the pain of a growing tumor, such as in bone metastasis (most ... However, radiotherapy, surgery and chemotherapy may produce painful conditions that persist long after treatment has ended. The ... doi:10.1007/978-0-387-87579-8. ISBN 978-0-387-87578-1. Hoskin PJ (2008). "Radiotherapy". In Sykes N, Bennett MI, Yuan CS (eds ... Potentially painful cancer treatments include: immunotherapy which may produce joint or muscle pain; radiotherapy, which can ...
... radiotherapy; and exposure to wind, ultraviolet light, or sunlight. The frequency and severity of recurrent outbreaks vary ... implications for clinical management of herpes simplex virus recurrence during radiotherapy". Oral Surg Oral Med Oral Pathol ...
... radiotherapy; or a combination of these modalities. Regardless of treatment type, 30 of the 36 cases of FA-DBCL for which there ...
... radiotherapy; general surgery; ear nose and throat surgery; ophthalmology; anaesthesia; intensive care pain management; ... Pediatric Surgery Pediatrics Pharmacy Physiotherapy Plastic and Re-Constructive Service Psychiatry Radiology Radiotherapy Renal ...
"Radiotherapy dose fractionation, second edition". The Royal College of Radiologists. 2016. Jones, Bleddyn; Morgan, David AL ( ... 2007). "Radiotherapy fractionation". In Dale, Roger G.; Jones, Bleddyn (eds.). Radiobiological modelling in radiation oncology ... radiation works to lower the effects of accelerated tumor growth that typically occurs during the later stages of radiotherapy ...
"Antiproton radiotherapy". Radiotherapy and Oncology. 86 (1): 14-19. doi:10.1016/j.radonc.2007.11.028. PMID 18158194. Madsen, N ...
Returning to KGMU, he served as the Dean of the Dean and head of the Radiotherapy Department at the institution. During brief ... "Radiotherapy- Awards-Publications-Dr MC Pant". Learning Ace. 2016. Retrieved 12 February 2016. "Founder Vice Chancellor". H.N.B ... He became the Director of the Department of Radiotherapy at KGMU in 2007 and held the post till 2010. In September 2010, he ... Ram Manohar Lohia Institute of Medical Sciences, Lucknow, and was the Dean and head of the Radiotherapy Department at the King ...
... (RNT, also known as unsealed source radiotherapy or molecular radiotherapy) uses radioactive substances ... Buscombe, J.; Navalkissoor, S. (1 August 2012). "Molecular radiotherapy". Clinical Medicine. 12 (4): 381-386. doi:10.7861/ ... "Palliative Radiotherapy for Bone Metastases: An ASTRO Evidence-Based Guideline". International Journal of Radiation Oncology, ...
This imaging information is fed into the software to allow real-time tracking and sub-millimetric accuracy during radiotherapy ... Lawler, Gavin (19 January 2022). "A review of surface guidance in extracranial stereotactic body radiotherapy (SBRT/SABR) for ... Mast, Mirjam (15 April 2022). "Introduction to: Surface Guided Radiotherapy (SGRT)". Technical Innovations & Patient Support in ... Radiotherapy and Oncology. 153: 34-42. doi:10.1016/j.radonc.2020.09.041. PMID 32987044. S2CID 222168459. Sarudis, Sebastian; ...
MLCs are used in external beam radiotherapy to provide conformal shaping of beams. Specifically, conformal radiotherapy and ... Takahashi, S (1965). "Conformation radiotherapy. Rotation techniques as applied to radiography and radiotherapy of cancer". ... For conformal radiotherapy the MLC allows conformal shaping of the beam to match the borders of the target tumour. For ... MLCs are now widely used and have become an integral part of any radiotherapy department. MLCs were primarily used for ...
She primarily worked in radiography and radiotherapy from this point forward. Armstrong worked with John Charnley during his ... Remarkable' Ethel Armstrong, 87, honoured with MBE for services to NHS and retirees". Action Radiotherapy. 1 January 2018. ...
Scriptable DICOM Server for Medical Image Management in Radiotherapy". Radiotherapy & Oncology. 106 (2): S488. doi:10.1016/ ...
The investigators observed no benefit to adjuvant radiotherapy after radical prostatectomy in patients with prostate cancer in ... In the study, 697 patients were randomly assigned to adjuvant radiotherapy and 699 to observation with salvage radiotherapy. ... said that the findings definitively confirm the value of observation with salvage radiotherapy over adjuvant radiotherapy in ... The aim of the RADICALS-RT study was to clarify the optimal timing for radiotherapy after radical prostatectomy in men with ...
Image-Guided Radiotherapy. The term image-guided radiotherapy (IGRT) refers to the use of additional verification tools in an ... What is hypofractionated radiotherapy?. What is the role of radiotherapy and androgen ablation in the treatment of prostate ... 3-Dimensional Conformal Radiotherapy. In 3-dimensional conformal radiotherapy (3D-CRT), the radiation beam is shaped to include ... Image-guided radiotherapy. The term image-guided radiotherapy (IGRT) refers to the use of imaging techniques, including the ...
Total density per million population: Radiotherapy units (Priority health technologies). This indicator is available in the ...
Pair of Elekta linacs gives German center the perfect solution for lung stereotactic radiotherapy. Mar 22, 2023 7 minute read ... Oklahoma centers stereotactic radiotherapy program thrives with linac addition. Mar 9, 2023 9 minute read ... Belgian cancer center streamlines radiotherapy service with addition of Elekta Harmony linacs. Oct 5, 2022 5 minute read ... Netherlands team debuts online adaptive radiotherapy workflow with Elekta CBCT linac. May 24, 2023 4 minute read ...
[Radiotherapy of choroid hemangiomas]
Researchers have been working to improve a treatment called proton beam radiotherapy. ... Unlike traditional radiotherapy, the radiation from proton beam radiotherapy can be confined largely to the tumour, minimising ... He added: "I think with proton provision in the UK now were probably treating slightly less than 2% of the radiotherapy ... The experts have developed a range of projects that significantly improve the accuracy of a type of radiotherapy treatment ...
024 - Radiotherapy Portal Imaging Quality (1987) Category: Reports The major goal of radiation therapy is the delivery of a ... These films are used by most radiotherapy institutions to evaluate the degree to which the actual delivered radiation therapy ... the only method commonly available for measuring and documenting the extent of geometric treatment accuracy is the radiotherapy ...
Our standards form the foundation for how we regulate, explaining what we expect of our registrants and education and training ...
Irelands expert booksellers. Free shipping on all online orders in Ireland. Browse best sellers, niche reads, new releases and much more.
Radiotherapy in soft tissue sarcoma , springermedizin.at Skip to main content Menü Home ... Radiotherapy in soft tissue sarcoma. verfasst von: Prof. Dr. Falk Röder Erschienen in: memo - Magazine of European Medical ... Radiotherapy to improve local control regardless of surgical margin and malignancy grade in extremity and trunk wall soft ... Radiotherapy to improve local control regardless of surgical margin and malignancy grade in extremity and trunk wall soft ...
To evaluate the effect of timing of radiotherapy (RT) on survival in patients with newly diagnosed primary glioblastoma (GBM) ... Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a ... Katsigiannis, S., Krischek, B., Barleanu, S. et al. Impact of time to initiation of radiotherapy on survival after resection of ... Waiting time to radiotherapy as a prognostic factor for glioblastoma patients in a scenario of medical disparities. Arq ...
The radiotherapy sessions are relatively quick, but most people are here five days a week for a number of weeks. ...
... radiotherapy technology for fast, precise, non-invasive cancer treatments have found that they are able to substantially... ... With RapidArc, doctors were able to quickly administer image-guided radiotherapy or radiosurgery treatments using fewer monitor ... Scientific Presentations at 2009 ASTRO Meeting Highlight RapidArc® Radiotherapy Technology from Varian Medical Systems Oncology ... Chicago, IL - November 10, 2009 - Clinicians using RapidArc® radiotherapy technology for fast, precise, non-invasive cancer ...
CID 9562 Radiotherapy Treatment Delivery Person Role Home CID 9564 Treatment Session Confirmation Assertion. ...
Radiotherapy waiting times DSS pilot collection 2013-15 page on the Australian Institute of Health and Welfare website ... Radiotherapy in Australia: report on a pilot data collection 2013-14. Radiotherapy in Australia: report on the second year of a ... Radiotherapy waiting times DSS pilot collection 2013-15. Print this page Click to open the social media sharing options Share ... The main purpose of the Radiotherapy waiting times data set specification (RWT DSS) is to describe the information that must be ...
Should mesothelioma patients consider having radiotherapy as a way to keep their symptoms from coming back after surgery? A new ... Radiotherapy May Still Help Prevent Mesothelioma Spread. Although the SMART trial data suggests that prophylactic radiotherapy ... the researchers found very little difference between radiotherapy started early and radiotherapy administered in response to ... Radiotherapy for Mesothelioma: Better But Still Limited. ByAlex Strauss December 20, 2013. March 26, 2019. ...
The Department for Radiotherapy treats more than 350 patients daily. Annually, the department treats over 5,000 patients and ... Head of the Division of Radiotherapy. Jasenka Gugić, MD, PhD. T: +386 1 5879 515 E: [email protected] ... Clinical departments of the Division of Radiotherapy provide hospital care to patients that require care during or after ... Accuracy is ensured using routine image-guided radiotherapy (IGRT). They also regularly use the total body irradiation (TBI) ...
Preparation for Radiotherapy Practice.. Year 2 Physics for Radiotherapy and Oncology Practice, Practice Education, Radiotherapy ... They deliver radiotherapy treatment using state-of-the-art equipment.. Radiotherapy radiographers work as part of the health ... Practice Education, Radiotherapy Treatment Planning and Brachytherapy, Radiotherapy and Oncology 3, Teams in Interprofessional ... Radiotherapy and Oncology. Glasgow Caledonian University. Add to Portfolio Add to Portfolio Download/Print this Course Download ...
However, most radiotherapy is delivered while patients are still breathing because many are not able to hold their breath for ... One of the most effective ways to treat breast cancer is with radiation therapy - radiotherapy - which is typically used in ... Training Cancer Patients To Hold Their Breath For Longer Than 5 Minutes May Help In Targeted Radiotherapy. May 13, 2016 02:26 ... The findings could make the process of receiving targeted radiotherapy easier on patients and greatly improve the long-term ...
Giant Basal Cell Carcinoma of the Face: Role of Radiotherapy. Husein Husein ElAhmed ...
Effect of postmastectomy radiotherapy in patients ,35 years old with stage II-III breast cancer treated with doxorubicin-based ... trials and meta-analyses have displayed improvements in local control and overall survival with postmastectomy radiotherapy ( ...
After surgery, the participants had to have received radiotherapy alone, chemotherapy alone or radiotherapy plus chemotherapy. ... assessed the role of chemotherapy alone or in addition to radiotherapy, or radiotherapy alone. One study was able to ... has been surgery followed by radiotherapy. However, the benefit of adjuvant (post-surgery) chemotherapy and radiotherapy is ... Does giving chemotherapy, radiotherapy or both improve survival in people with rare (anaplastic oligodendrogliomas and ...
This results in biologically effective doses that may be two to three times higher than with conventional radiotherapy (RT). ... Mayles WP; Radiotherapy Development Board. Clin Oncol (R Coll Radiol) 2010;22:636-42. ...
Joshi on BCAN discussion regarding radiotherapy in bladder cancer treatment Aug 1, 2023. Urology Times staff ... You are participating in the BCAN Think Tank discussion "Beyond bladder preservation: Radiotherapy across the spectrum of ...
Among the 933, 109 received adjuvant radiotherapy, 379 received no radiotherapy, and 445 received early salvage radiotherapy. ... 19,733 received no radiotherapy, and 3,570 received early salvage radiotherapy. Compared with early salvage radiotherapy, no ... 428 received adjuvant radiotherapy, 965 received no radiotherapy, and 1,031 received early salvage radiotherapy. ... On multivariate analysis, compared with early salvage radiotherapy, men receiving adjuvant radiotherapy had significantly lower ...
First is a review on attitudes towards palliative radiotherapy (to treat painful bone metastases) regarding the 8 Gy in a ... Katrina editorial; terminal sedation; palliative radiotherapy; quality measures 1). NEJM has an editorial about the Katrina ...
Association between pelvic nodal radiotherapy and patient-reported functional outcomes through 5 years among men undergoing ... Association between pelvic nodal radiotherapy and patient-reported functional outcomes through 5 years among men undergoing ... external-beam radiotherapy for prostate cancer: An assessment of the comparative effectiveness analysis of surgery and ... external-beam radiotherapy for prostate cancer: An assessment of the comparative effectiveness analysis of surgery and ...
Radiotherapy*. Radiotherapy Simulation Champion secondment. Radiotherapy Simulation Champion secondment. Nicky Hutton and Sarah ... Radiotherapy Radiotherapy practice in detail*Public Health Strategy Radiographers and the public health agenda*Professional ... Radiotherapy Managers UK Radiotherapy Service Managers Group.*Developing Tomorrows Leaders (ETM) Essential Training for ...
A Hematopoietic Stromal Lesion Associated with Fractionated Radiotherapy (FxRT): Time- and Dose-effects. C. J. KOVACS, M. J. ... A Hematopoietic Stromal Lesion Associated with Fractionated Radiotherapy (FxRT): Time- and Dose-effects ... A Hematopoietic Stromal Lesion Associated with Fractionated Radiotherapy (FxRT): Time- and Dose-effects ... A Hematopoietic Stromal Lesion Associated with Fractionated Radiotherapy (FxRT): Time- and Dose-effects ...
A leading radiotherapy equipment supplier sought a high-resolution lens able to withstand, and precisely focus, the high levels ... As increasing numbers of people require radiotherapy as a key part of their cancer treatment, there is a need for treatment ... This new lens is enabling the supplier to improve the precision radiotherapy treatment of tumours that its equipment provides. ...
  • Radiotherapy is categorised under the Oncology speciality, and can be delivered in conjunction with other cancer treatments such as chemotherapy and surgery. (royalberkshire.nhs.uk)
  • For patients on regular treatment schedules in radiotherapy and chemotherapy, the department will issue a car parking permit for the length of your treatment. (royalberkshire.nhs.uk)
  • The standard of care for patients with newly diagnosed GBM comprises maximum safe resection of the tumor followed by radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy [ 3 , 4 ]. (springer.com)
  • A team of medical researchers in Italy have achieved what they are calling "excellent" tumor control and survival results in malignant pleural mesothelioma patients using a combination of surgery, chemotherapy, and radiotherapy. (survivingmesothelioma.com)
  • Does giving chemotherapy, radiotherapy or both improve survival in people with rare (anaplastic oligodendrogliomas and oligoastrocytomas) brain tumours? (cochrane.org)
  • However, the benefit of adjuvant (post-surgery) chemotherapy and radiotherapy is still unclear. (cochrane.org)
  • After surgery, the participants had to have received radiotherapy alone, chemotherapy alone or radiotherapy plus chemotherapy. (cochrane.org)
  • Three randomized controlled trials, which included 931 participants, assessed the role of chemotherapy alone or in addition to radiotherapy, or radiotherapy alone. (cochrane.org)
  • One study was able to demonstrate a significant survival benefit for the addition of chemotherapy to radiotherapy after surgery, compared with radiotherapy alone. (cochrane.org)
  • Furthermore, in one study, these specific chromosome deletions and mutations predicted which group of participants derived benefit from the addition of chemotherapy to radiotherapy after surgery. (cochrane.org)
  • Evidence for giving radiotherapy and chemotherapy was of good quality, but sparse. (cochrane.org)
  • The benefit of adjuvant chemotherapy and radiotherapy (RT), given as single modalities or sequentially, is still unclear. (cochrane.org)
  • More decision regret was associated with volumetric modulated arc therapy , chest wall irradiation, use of docetaxel as a chemotherapy agent, lymphangiosis carcinomatosa, new heart disease after radiotherapy , and lower psychological well-being . (bvsalud.org)
  • Stereotactic Ablative Body Radiotherapy (SABR) to the lymph nodes involves the precise delivery of high dose radiotherapy. (christie.nhs.uk)
  • Besides the 3-dimensional conformal radiation therapy (3D CRT), they regularly perform all the most modern radiotherapy techniques: intensity-modulated radiation therapy (IMRT), volumetric-modulated arc therapy (VMAT), and stereotactic techniques like stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). (onko-i.si)
  • Advanced radiation techniques like high-dose stereotactic body radiotherapy (SBRT) offer the opportunity to deliver high radiation doses to tumors while sparing surrounding tissues. (uclahealth.org)
  • All patients receiving a course of radiotherapy will have the opportunity to discuss their treatment plan with their Consultant, and the Radiographers. (royalberkshire.nhs.uk)
  • Our final results are expected later this year, but we are extremely optimistic by what we're seeing, and hope this technology will soon begin to offer men undergoing radiotherapy for prostate cancer better outcomes. (uclahealth.org)
  • Accuracy is ensured using routine image-guided radiotherapy (IGRT). (onko-i.si)
  • Adjuvant radiotherapy after radical prostatectomy provided no meaningful benefit in patients with prostate cancer but increased the risk for urinary and bowel morbidity compared with men followed with observation alone, according to the latest results from the phase 3 RADICALS-RT trial. (medscape.com)
  • The addition of 24 months of androgen-deprivation therapy to postoperative radiotherapy after radical prostatectomy provided a metastasis-free survival benefit and improved the time to salvage therapy in patients with prostate cancer, according to the preliminary results from the RADICALS-HD trial (ISRCTN40814031). (ascopost.com)
  • Observation with early salvage radiotherapy in cases of biochemical failure should be the standard of care, concluded study co-author Noel Clarke, MBBS, who presented the results at the European Society for Medical Oncology (ESMO) Congress 2023 in Madrid on October 20. (medscape.com)
  • Data from the Radiation Therapy Oncology Group (RTOG) have shown a clear improvement in biochemical control of disease when patients receive a combination of radiotherapy and androgen-suppressive treatment. (medscape.com)
  • Applied Clinical Anatomy, Radiotherapy and Oncology, Fundamentals of Human Physiology, Foundations for Interprofessional Practice, Preparation for Radiotherapy Practice. (planitplus.net)
  • Physics for Radiotherapy and Oncology Practice, Practice Education, Radiotherapy and Oncology 2, Working in Interprofessional Teams. (planitplus.net)
  • Practice Education, Radiotherapy Treatment Planning and Brachytherapy, Radiotherapy and Oncology 3, Teams in Interprofessional Practice, Research Methods for Effective Practice. (planitplus.net)
  • Objectives: Understand the socio-demographic and clinical profile of patients who show psychological risk by screening them using the Psychological Risk in Oncology (IRPO) during the radiotherapy treatment. (bvsalud.org)
  • The new findings showed no difference in the rate of 10-year freedom from distant metastases or overall survival in patients who received adjuvant radiotherapy vs those who underwent observation with salvage radiotherapy if their disease progressed and provided further confirmation of earlier results reported in The Lancet in 2020 . (medscape.com)
  • Invited discussant and session co-chair Shahneen Sandhu, MBBS, said that the findings definitively confirm the value of observation with salvage radiotherapy over adjuvant radiotherapy in this patient population. (medscape.com)
  • In the study, 697 patients were randomly assigned to adjuvant radiotherapy and 699 to observation with salvage radiotherapy. (medscape.com)
  • However, self-reported urinary and fecal incontinence rates at 1 year were significantly higher in the adjuvant radiotherapy group vs the observation group, 60% of whom had not received salvage radiotherapy at that time. (medscape.com)
  • Decision regret in breast cancer patients after adjuvant radiotherapy. (bvsalud.org)
  • We evaluated decision regret and physical and psychological well-being among breast cancer patients who underwent adjuvant radiotherapy and explored their associations with patient , tumor , treatment , and symptom characteristics. (bvsalud.org)
  • Between the two radiotherapy sites at Reading and Bracknell, the department is well equipped with two CT scanners and virtual simulation software systems, a superficial X-ray unit, a high dose Brachytherapy unit, and four Elekta Linear Accelerators with the provision of external beam radiotherapy. (royalberkshire.nhs.uk)
  • Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomized trial. (springermedizin.at)
  • Flash treatments can be delivered in fewer or even single deliveries in comparison to conventional radiotherapy which is often delivered in fractions over a period of about six weeks with the patient needing to attend hospital every day. (yahoo.com)
  • Unit used to deliver conventional external beam radiotherapy. (medscape.com)
  • SABR is given over fewer treatment sessions than conventional/standard radiotherapy which may increase the chances of controlling the tumour at the treatment site and reducing pain more effectively than standard radiotherapy. (christie.nhs.uk)
  • The trial included 203 malignant pleural mesothelioma patients who had one of these large bore procedures and subsequently underwent either prophylactic radiotherapy (started before new tumors appeared) or deferred radiotherapy that was based on their symptoms. (survivingmesothelioma.com)
  • The aim of this study was to verify the information in the literature, applications and implications of radiotherapy in mouth's tumors. (bvsalud.org)
  • The approach of early salvage radiotherapy spared morbidity [from] radiation in the vast majority of patients, and further bowel and bladder toxicity is reduced in the setting of salvage radiotherapy," said Sandhu, an associate professor and consultant medical oncologist at Peter MacCallum Cancer Centre, Victoria, Australia. (medscape.com)
  • Patients in the observation arm received salvage radiotherapy if they experienced two consecutive PSA increases ≥ 0.1 ng/mL or three consecutive rises. (medscape.com)
  • It is estimated that more than half of cancer patients undergo radiotherapy during the course of their treatment. (unboundmedicine.com)
  • Although improvements in radiotherapy techniques and instruments could reduce these side effects, there are still important concerns for cancer patients. (unboundmedicine.com)
  • To evaluate the effect of timing of radiotherapy (RT) on survival in patients with newly diagnosed primary glioblastoma (GBM) treated with the same therapeutical protocol. (springer.com)
  • Should mesothelioma patients consider having radiotherapy as a way to keep their symptoms from coming back after surgery? (survivingmesothelioma.com)
  • In an article published in the online medical journal PLoS One , researchers concluded that radiotherapy aimed at stopping the spread of pleural mesothelioma and delaying the return of symptoms may not not have much of an impact on quality of life for patients. (survivingmesothelioma.com)
  • Using quality of life data from the SMART patients, researchers from Dalhousie University and the University of Saskatchewan in Canada and the University of Bristol in the UK determined that the prophylactic radiotherapy did not improve patients' lives enough to make it worth the cost. (survivingmesothelioma.com)
  • Mesothelioma patients in the SMART trial were asked to fill out quality of life questionnaires to determine how big an impact radiotherapy had. (survivingmesothelioma.com)
  • The Department for Radiotherapy treats more than 350 patients daily. (onko-i.si)
  • Clinical departments of the Division of Radiotherapy provide hospital care to patients that require care during or after treatment (poor general state, additional diagnostic examinations, and treatment of radiation therapy side effects). (onko-i.si)
  • Overall, 23% of patients had pT3b/T4 disease, and the median prostate-specific antigen (PSA) level was 0.22 ng/mL before radiotherapy. (ascopost.com)
  • Method: 262 medical records of adult patients who had undergone radiotherapy treatment in 2018 and 2019 and responded to IRPO were evaluated. (bvsalud.org)
  • Decision regret regarding the radiotherapy was assessed using the Ottawa Decision Regret Scale, physical and psychological well-being were assessed using the PROMIS Global Health -10 questionnaire , and patients were asked about their treatment outcomes and symptoms. (bvsalud.org)
  • Our findings suggest that psychological well-being influences patients ' satisfaction with therapy decisions, implying that practitioners should pay special attention to maintaining psychological well-being during shared decision -making and ensuring that psychological assessment and treatment is provided after cancer therapy to deal with long-term effects of radiotherapy . (bvsalud.org)
  • The experts have developed a range of projects that significantly improve the accuracy of a type of radiotherapy treatment called proton beam radiotherapy. (yahoo.com)
  • However, in order to make the most of the treatment, the accuracy of the radiation dose from proton beam treatment must be similar to that achieved using existing radiotherapy treatments. (yahoo.com)
  • At present, the only method commonly available for measuring and documenting the extent of geometric treatment accuracy is the radiotherapy portal film. (aapm.org)
  • These films are used by most radiotherapy institutions to evaluate the degree to which the actual delivered radiation therapy matches the planned treatment. (aapm.org)
  • This training ensures users are competent and confident using HyperArc® high-definition radiotherapy within the Eclipse™ treatment planning system and TrueBeam® radiotherapy system. (varian.com)
  • You will have appointments in the radiotherapy department before you start the treatment. (christie.nhs.uk)
  • Radiotherapy is the provision of high energy ionizing radiation treatment to control or destroy malignant cancer cells and can be curative or palliative, depending on the patient's histology and staging. (royalberkshire.nhs.uk)
  • The department currently provides the following types of radiotherapy, depending on each patient's individual treatment regime. (royalberkshire.nhs.uk)
  • Adaptive radiotherapy: the treatment is adapted during each fraction, to account for patient internal anatomical changes. (royalberkshire.nhs.uk)
  • The time between the patient's ready-for-care date and the date of the first megavoltage external beam radiotherapy treatment. (aihw.gov.au)
  • Establishments in scope are those healthcare establishments that provide megavoltage external beam radiotherapy treatment (in-scope radiotherapy treatment). (aihw.gov.au)
  • People in scope are those who started a course of radiotherapy treatment within the reference period. (aihw.gov.au)
  • They deliver radiotherapy treatment using state-of-the-art equipment. (planitplus.net)
  • When men are getting radiotherapy for prostate cancer as their initial treatment, we know the addition of hormone therapy improves efficacy and survival. (ascopost.com)
  • Radiotherapy treatment planning / Richard F. Mould. (who.int)
  • Radiotherapy radiographers work as part of the health care team and are involved in decisions about radiotherapy patient management. (planitplus.net)
  • The results of several phase III clinical trials suggest that the true benefit of combining radiotherapy with androgen blockade may lie in the potentially synergistic effects of the 2 treatments. (medscape.com)
  • This maintains the precision required for specific radiotherapy treatments. (royalberkshire.nhs.uk)
  • The report "Global Radiotherapy Market by Products (Proton Therapy, Linear Accelerator, CyberKnife, Gamma Knife and TomoTherapy)- Market Outlook 2022" provides an in-depth analysis of global radiotherapy market focusing on external beam radiation therapy products such as Proton Therapy, Linear Accelerator, CyberKnife, Gamma Knife and TomoTherapy. (bharatbook.com)
  • Radiotherapy to improve local control regardless of surgical margin and malignancy grade in extremity and trunk wall soft tissue sarcoma: a Scandinavian sarcoma group study. (springermedizin.at)
  • That recently-released finding comes from data collected during the Surgical and Large Bore Procedures in Malignant Pleural Mesothelioma and Radiotherapy (SMART) trial, a multicenter trial based in the UK. (survivingmesothelioma.com)
  • Unlike traditional radiotherapy, the radiation from proton beam radiotherapy can be confined largely to the tumour, minimising the damage to surrounding healthy tissue. (yahoo.com)
  • Currently, any form of radiotherapy results in unwanted but unavoidable deposition of radiation to healthy tissue around the targeted tumour. (yahoo.com)
  • The dose contribution due to photonuclear reactions during radiotherapy / by Peter D. Allen and M. Anwar Chaudhri. (who.int)
  • The results show that, in some cases, radiotherapy may be as effective as surgery, if properly displayed, performed and complied with the particular patient, stage and tumor location. (bvsalud.org)
  • The aim of the RADICALS-RT study was to clarify the optimal timing for radiotherapy after radical prostatectomy in men with prostate cancer, which previously had been uncertain. (medscape.com)
  • In 3-dimensional conformal radiotherapy (3D-CRT), the radiation beam is shaped to include the 3D anatomic configuration of the prostate and any specified adjacent tissue (including the seminal vesicles and periprostatic adventitial tissues). (medscape.com)
  • In the past decade, several randomized trials and meta-analyses have displayed improvements in local control and overall survival with postmastectomy radiotherapy (PMRT) for locally advanced breast cancer, but have failed to report age-specific results. (oncolink.org)
  • This therapy can more precisely target tumours without damaging surrounding healthy tissue, minimising the side effects of radiotherapy - particularly in children - such as heart failure, pulmonary fibrosis, and secondary cancer. (yahoo.com)
  • The Radiotherapy Department is situated within the Berkshire Cancer Centre (BCC), along with further service provision at the Royal Berkshire Bracknell Clinic. (royalberkshire.nhs.uk)
  • A variety of cancer types and sites can be treated with radiotherapy, allowing its provision to reach the wider cancer population. (royalberkshire.nhs.uk)
  • A single patient was excluded due to an MRI artifact caused by a hemostatic substance injected near the target during surgery preceding radiotherapy. (lu.se)
  • However, when men are getting radiotherapy after surgery, we have much less data about the role of hormone therapy. (ascopost.com)
  • However, overall survival was not improved with a long vs short course of androgen-deprivation therapy with radiotherapy after surgery. (ascopost.com)
  • Traditionally, the standard of care for people with rare anaplastic oligodendrogliomas and anaplastic oligoastrocytomas (brain tumours) has been surgery followed by radiotherapy. (cochrane.org)
  • Overall, the trial results "support the use of early salvage radiotherapy for PSA failure after radical prostatectomy rather than early adjuvant intervention, " concluded Clarke, a professor and consultant urologist at The Christie Hospital and Salford Royal Hospital, Manchester, United Kingdom. (medscape.com)
  • Based on the first results of the RADICALS-HD trial, 24 months of androgen-deprivation therapy with radiotherapy after radical prostatectomy improved metastasis-free survival, compared with 6 months of androgen-deprivation therapy, with a 10-year rate of metastasis-free survival of 78% vs 72%, respectively. (ascopost.com)
  • Internationally acknowledged high proficiency and excellence enable the Division of Radiotherapy to serve as a learning centre of the International Atomic Energy Agency (IAEA) for teaching foreign professionals in the field of radiotherapy. (onko-i.si)
  • There was no significant effect of prophylactic radiotherapy on quality of life in the intervention group, nor was there any discernible decrease in healthcare costs," writes lead study author Samuel Alan Stewart of Dalhousie University. (survivingmesothelioma.com)
  • Surface guided radiotherapy: SGRT uses sophisticated 3D camera technology to allow real time visualisation of the patient's surface and any physical movements during Radiotherapy. (royalberkshire.nhs.uk)
  • The questionnaire was administered 14 months to 4 years after completion of radiotherapy . (bvsalud.org)
  • Objectives: MRI-only radiotherapy (RT) provides a workflow to decrease the geometric uncertainty introduced by the image registration process between MRI and CT data and to streamline the RT planning. (lu.se)
  • In addition, melatonin has shown the ability to inhibit long-term changes in inflammatory responses at different levels, thereby ameliorating late side effects of radiotherapy. (unboundmedicine.com)
  • He added: "I think with proton provision in the UK now we're probably treating slightly less than 2% of the radiotherapy population that would benefit - 5% to 20% is the estimate. (yahoo.com)
  • There is little evidence to suggest that prophylactic radiotherapy is a cost-effective intervention in this population. (survivingmesothelioma.com)
  • Although the SMART trial data suggests that prophylactic radiotherapy may not have much impact on quality of life for people diagnosed with mesothelioma , there is still evidence that it may help keep mesothelioma from spreading and extend survival. (survivingmesothelioma.com)
  • Thirdly, they are performing pioneering measurements to demonstrate a new form of radiotherapy called Flash RT. (yahoo.com)
  • According to the study, the time to salvage therapy was delayed with 24 months vs 6 months of androgen-deprivation therapy with radiotherapy. (ascopost.com)
  • Conclusion: We report a successful clinical study of MRI-only brain radiotherapy, conducted using both prospective and retrospective analysis. (lu.se)
  • It is necessary that the prior action of the dentist in order to minimize the effects of oral radiotherapy in addition to its performance in order to promote the early and differential diagnosis of mouth's lesions. (bvsalud.org)