Method for assessing flow through a system by injection of a known quantity of radionuclide into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)
Methods for assessing flow through a system by injection of a known quantity of an indicator, such as a dye, radionuclide, or chilled liquid, into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)
Method for assessing flow through a system by injection of a known quantity of dye into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Unstable isotopes of zinc that decay or disintegrate emitting radiation. Zn atoms with atomic weights 60-63, 65, 69, 71, and 72 are radioactive zinc isotopes.
The making of a radiograph of an object or tissue by recording on a photographic plate the radiation emitted by radioactive material within the object. (Dorland, 27th ed)
Devices used to measure the flow of fluids (see RHEOLOGY) or the AIR to measure RESPIRATION.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
A genus of gram-negative, rod-shaped, gliding bacteria in the family XANTHOMONADACEAE. Strongly proteolytic, it is involved in lysing a variety of microorganisms.
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Substances or mixtures that are added to the soil to supply nutrients or to make available nutrients already present in the soil, in order to increase plant growth and productivity.
A group of water-soluble vitamins, some of which are COENZYMES.
A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.
PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.
VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.
Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)
Stable sodium atoms that have the same atomic number as the element sodium, but differ in atomic weight. Na-23 is a stable sodium isotope.
Fluids composed mainly of water found within the body.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
A republic in western Africa, south of BURKINA FASO and west of TOGO. Its capital is Accra.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
The relative amounts of various components in the body, such as percentage of body fat.
The production and release of substances such as NEUROTRANSMITTERS or HORMONES from nerve cells.
Cellular release of material within membrane-limited vesicles by fusion of the vesicles with the CELL MEMBRANE.
An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
Cells that store epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia (PARAGANGLIA, CHROMAFFIN) of the sympathetic nervous system.
Radiography of the bronchial tree after injection of a contrast medium.
Condensed areas of cellular material that may be bounded by a membrane.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.
A noninvasive method for assessing BODY COMPOSITION. It is based on the differential absorption of X-RAYS (or GAMMA RAYS) by different tissues such as bone, fat and other soft tissues. The source of (X-ray or gamma-ray) photon beam is generated either from radioisotopes such as GADOLINIUM 153, IODINE 125, or Americanium 241 which emit GAMMA RAYS in the appropriate range; or from an X-ray tube which produces X-RAYS in the desired range. It is primarily used for quantitating BONE MINERAL CONTENT, especially for the diagnosis of OSTEOPOROSIS, and also in measuring BONE MINERALIZATION.

Redundant systems of phosphatidic acid biosynthesis via acylation of glycerol-3-phosphate or dihydroxyacetone phosphate in the yeast Saccharomyces cerevisiae. (1/749)

In the yeast Saccharomyces cerevisiae lipid particles harbor two acyltransferases, Gat1p and Slc1p, which catalyze subsequent steps of acylation required for the formation of phosphatidic acid. Both enzymes are also components of the endoplasmic reticulum, but this compartment contains additional acyltransferase(s) involved in the biosynthesis of phosphatidic acid (K. Athenstaedt and G. Daum, J. Bacteriol. 179:7611-7616, 1997). Using the gat1 mutant strain TTA1, we show here that Gat1p present in both subcellular fractions accepts glycerol-3-phosphate and dihydroxyacetone phosphate as a substrate. Similarly, the additional acyltransferase(s) present in the endoplasmic reticulum can acylate both precursors. In contrast, yeast mitochondria harbor an enzyme(s) that significantly prefers dihydroxyacetone phosphate as a substrate for acylation, suggesting that at least one additional independent acyltransferase is present in this organelle. Surprisingly, enzymatic activity of 1-acyldihydroxyacetone phosphate reductase, which is required for the conversion of 1-acyldihydroxyacetone phosphate to 1-acylglycerol-3-phosphate (lysophosphatidic acid), is detectable only in lipid particles and the endoplasmic reticulum and not in mitochondria. In vivo labeling of wild-type cells with [2-3H, U-14C]glycerol revealed that both glycerol-3-phosphate and dihydroxyacetone phosphate can be incorporated as a backbone of glycerolipids. In the gat1 mutant and the 1-acylglycerol-3-phosphate acyltransferase slc1 mutant, the dihydroxyacetone phosphate pathway of phosphatidic acid biosynthesis is slightly preferred as compared to the wild type. Thus, mutations of the major acyltransferases Gat1p and Slc1p lead to an increased contribution of mitochondrial acyltransferase(s) to glycerolipid synthesis due to their substrate preference for dihydroxyacetone phosphate.  (+info)

Effect of obesity on red cell mass results. (2/749)

Measurement of red cell mass with isotope dilution remains an important diagnostic test in the evaluation of patients with suspected polycythemia vera (PCV). Results and reference ranges are typically expressed in units normalized for body weight (mL/kg). Obesity is common in polycythemic patients, and it is important to know how the various published normative ranges compare across a wide range of body weights. METHODS: We retrospectively reviewed 51 consecutive patients referred for red cell mass determination with 51Cr red blood cell dilution. Results were expressed in milliliters per kilogram (mL/kg) by using the actual patient weight and after adiposity adjustments using ideal body weight, body mass index (BMI) and combinations of height-weight, including body surface area. Results were classified as normal, elevated or PCV. RESULTS: There was a high prevalence of obesity in our population (28/51 [55%] with BMI > 27 kg/m2, BMI range 16.0-54.8 kg/m2). The method used to compensate for obesity had a dramatic effect on the derived red cell mass, the fraction of patients with elevated measurements and the fraction of patients meeting criteria for PCV. Concordance for categorization as normal, elevated or PCV by all methods was only 47.1%. CONCLUSION: Obesity is a common confounding factor in the interpretation of red cell mass measurements. Currently published reference ranges generate inconsistent results when extrapolated to obese patients. Further normative data on obese subjects are needed to determine which method (if any) is optimal.  (+info)

Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis. (3/749)

Vitamin C (L-ascorbic acid; AsA) acts as a potent antioxidant and cellular reductant in plants and animals. AsA has long been known to have many critical physiological roles in plants, yet its biosynthesis is only currently being defined. A pathway for AsA biosynthesis that features GDP-mannose and L-galactose has recently been proposed for plants. We have isolated a collection of AsA-deficient mutants of Arabidopsis thaliana that are valuable tools for testing of an AsA biosynthetic pathway. The best-characterized of these mutants (vtc1) contains approximately 25% of wild-type AsA and is defective in AsA biosynthesis. By using a combination of biochemical, molecular, and genetic techniques, we have demonstrated that the VTC1 locus encodes a GDP-mannose pyrophosphorylase (mannose-1-P guanyltransferase). This enzyme provides GDP-mannose, which is used for cell wall carbohydrate biosynthesis and protein glycosylation as well as for AsA biosynthesis. In addition to genetically defining the first locus involved in AsA biosynthesis, this work highlights the power of using traditional mutagenesis techniques coupled with the Arabidopsis Genome Initiative to rapidly clone physiologically important genes.  (+info)

Effects of a high-fat diet and voluntary wheel running on gluconeogenesis and lipolysis in rats. (4/749)

The purpose of the present study was to determine the effects of diet composition and exercise on glycerol and glucose appearance rate (Ra) and on nonglycerol gluconeogenesis (Gneo) in vivo. Male Wistar rats were fed a high-starch diet (St, 68% of energy as cornstarch, 12% corn oil) for a 2-wk baseline period and then were randomly assigned to one of four experimental groups: St (n = 7), high-fat (HF; 35% cornstarch, 45% corn oil; n = 8), St with free access to exercise wheels (StEx; n = 7), and HF with free access to exercise wheels (HFEx; n = 7). After 8 wk, glucose Ra when using [3-3H]glucose, glycerol Ra when using [2H5]glycerol (estimate of whole body lipolysis), and [3-13C]alanine incorporation into glucose (estimate of alanine Gneo) were determined. Body weight and fat pad mass were significantly (P < 0.05) decreased in exercise vs. sedentary animals only. The average amount of exercise was not significantly different between StEx (3,212 +/- 659 m/day) and HFEx (3,581 +/- 765 m/day). The ratio of glucose to alanine enrichment and absolute glycerol Ra (micromol/min) were higher (P < 0.05) in HF and HFEx compared with St and StEx rats. In separate experiments, the ratio of 3H in C-2 to C-6 of glucose from 3H2O (estimate of Gneo from pyruvate) was also higher (P < 0.05) in HF (n = 5) and HFEx (n = 5), compared with St (n = 5) and StEx (n = 5) rats. Voluntary wheel running did not significantly increase estimated alanine or pyruvate Gneo or absolute glycerol Ra. Voluntary wheel running increased (P < 0.05) glycerol Ra when normalized to fat pad mass. These data suggest that a high-fat diet can increase in vivo Gneo from precursors that pass through pyruvate. They also suggest that changes in the absolute rate of glycerol Ra may contribute to the high-fat diet-induced increase in Gneo.  (+info)

Glucose effectiveness is the major determinant of intravenous glucose tolerance in the rat. (5/749)

To determine the importance of insulin for glucose disposal during an intravenous glucose tolerance test in rats, experiments were performed in four cohorts of conscious unrestrained rats fasted overnight. In cohorts 1-3, a bolus of tracer ([3-3H]glucose, 50 microCi) was given alone, with glucose (0.3 g/kg) to induce an endogenous insulin response (approximately 1,100 pmol/l), or with exogenous insulin to give physiological (1,700 pmol/l) or supraphysiological (12,000 pmol/l) plasma levels. Raising plasma insulin within the physiological range had no effect (P > 0.05), but supraphysiological levels induced hypoglycemia (7.3 +/- 0.2 to 3.6 +/- 0.2 mmol/l) and increased [3H]glucose disappearance rate (P < 0.001). In cohort 4, a primed, continuous tracer infusion was started 120 min before saline or glucose bolus injection. [3H]glucose levels fell 15-20%, and the disappearance rate rose 36% (P < 0.05) after glucose injection. These results indicate that in fasted rats a tracer bolus injection protocol is not sufficiently sensitive to measure the physiological effect of insulin released in response to a bolus of glucose because this effect of insulin is small. Glucose itself is the predominant mediator of glucose disposal after a bolus of glucose in the fasted rat.  (+info)

The use of infrared spectrophotometry for measuring body water spaces. (6/749)

BACKGROUND: The conventional method of measuring total body water by the deuterium isotope dilution method uses gas isotope ratio mass spectrometry (IRMS), which is both expensive and time-consuming. We investigated an alternative method, using Fourier transform infrared spectrophotometry (FTIR), which uses less expensive instrumentation and requires little sample preparation. METHOD: Total body water measurements in human subjects were made by obtaining plasma, saliva, and urine samples before and after oral dosing with 1.5 mol of deuterium oxide. The enrichments of the body fluids were determined from the FTIR spectra in the range 1800-2800 cm-1, using a novel algorithm for estimation of instrumental response, and by IRMS for comparison. RESULTS: The CV (n = 5) for repeat determinations of deuterium oxide in biological fluids and calibrator solutions (400-1000 micromol/mol) was found to be in the range 0.1-0.9%. The use of the novel algorithm instead of the integration routines supplied with the instrument gave at least a threefold increase in precision, and there was no significant difference between the results obtained with FTIR and those obtained with IRMS. CONCLUSION: This improved infrared method for measuring deuterium enrichment in plasma and saliva requires no sample preparation, is rapid, and has potential value to the clinician.  (+info)

Contribution of glucose transport to the control of the glycolytic flux in Trypanosoma brucei. (7/749)

The rate of glucose transport across the plasma membrane of the bloodstream form of Trypanosoma brucei was modulated by titration of the hexose transporter with the inhibitor phloretin, and the effect on the glycolytic flux was measured. A rapid glucose uptake assay was developed to measure the transport activity independently of the glycolytic flux. Phloretin proved a competitive inhibitor. When the effect of the intracellular glucose concentration on the inhibition was taken into account, the flux control coefficient of the glucose transporter was between 0.3 and 0.5 at 5 mM glucose. Because the flux control coefficients of all steps in a metabolic pathway sum to 1, this result proves that glucose transport is not the rate-limiting step of trypanosome glycolysis. Under physiological conditions, transport shares the control with other steps. At glucose concentrations much lower than physiological, the glucose carrier assumed all control, in close agreement with model predictions.  (+info)

Method for the determination of total homocysteine in plasma and urine by stable isotope dilution and electrospray tandem mass spectrometry. (8/749)

BACKGROUND: Total homocysteine (tHcy) has emerged as an important independent risk factor for cardiovascular disease. Analytical methods are needed to accommodate the high testing volumes for tHcy and provide rapid turnaround. METHODS: We developed liquid chromatography electrospray tandem mass spectrometry (LC-MS/MS) method based on the analysis of 100 microL of either plasma or urine with homocystine-d(8) (2 nmol) added as internal standard. After sample reduction and deproteinization, the analysis was performed in the multiple reaction monitoring mode in which tHcy and Hcy-d(4) were detected through the transition from the precursor to the product ion (m/z 136 to m/z 90 and m/z 140 to m/z 94, respectively). The retention time of tHcy and Hcy-d(4) was 1.5 min in a 2.5-min analysis. RESULTS: Daily calibrations between 2.5 and 60 micromol/L exhibited consistent linearity and reproducibility. At a plasma concentration of 0.8 micromol/L, the signal-to-noise ratio for tHcy was 17:1. The regression equation for the comparison between our previous HPLC method (y) and the LC-MS/MS method (x) was y = 1.097x - 1.377 (r = 0.975; S(y|x) =1.595 micromol/L; n = 367), and for comparison between a fluorescence polarization immunoassay (Abbott IMx; y) and LC-MS/MS (x) was y = 1.039x + 0.025 (r = 0.969; S(y|x) =1.146 micromol/L; n = 367). Inter- and intraassay CVs were 2.9-5.9% and 3.6-5.3%, respectively, at mean concentrations of 3.9, 22.7, and 52.8 micromol/L. Mean recovery of tHcy was 94.2% (20 micromol/L) and 97.8% (50 micromol/L). CONCLUSIONS: The sensitivity and specificity of tandem mass spectrometry are well suited to perform high-volume analysis of tHcy. Reagents are inexpensive and sample preparation of a batch of 40 specimens is completed in less than 1 h and is amenable to automation.  (+info)

A slightly modified procedure of direct substoichiometric isotope dilution analysis is theoretically treated and its advantages are stated. The precision of one case of reverse isotope dilution is...
1. Standard radioisotope dilution techniques employing [3H]water and [22Na]sodium chloride have been used to determine the total body water and total exchangeable sodium of 20 male and 10 female normal Ghanaians (Africans) aged 19-25 years.. 2. Lean body mass and total body fat are calculated as a percentage of body weight; the total exchangeable sodium values have been expressed in relation to lean body mass.. 3. Comparison of the data for Ghanaian subjects with published figures for Caucasian subjects of similar age shows that the Ghanaian men have much less total body fat and the women a little less total body fat than their Caucasian counterparts.. 4. Total exchangeable sodium expressed in terms of lean body mass shows close agreement in both men and women. ...
Mercury speciation in solid sample matrices has been investigated using high performance liquid chromatography (HPLC) coupled with multicollector sector field (MCSF) and quadrupole (Q) inductively coupled plasma mass spectrometry (ICP-MS) for species specific isotope dilution mass spectrometry (IDMS). 199Hg enriched methylmercurychloride has been synthesised and recovered in the solid form for use as a spike material. The stability of methylmercury during the IDMS procedure was investigated using 199Hg and 13C labelled methylmercury isotopomers and ¹H Nuclear Magnetic Resonance spectroscopy. IntermoIecuJar exchange of the methylmercury halide counter ion was observed, the halide counter ion order of preference was l,Br,Cl. No evidence was found for the decomposition, or formation, of methylmercury during equilibration with soil (NIST2710 SRM) or dogfish muscle (DORM-2 CRM), or during chromatographic separation. The extent of equilibration between the spike and the particulate bound mercury ...
Bodystat Quadscan 4000 Touch Screen. Used internationally in medical research and clinical applications, the Bodystat Quadscan 4000 Touch Screen multi-frequency Bioelectrical Analyser offers a quick, easy, portable and economical non-invasive alternative to other methods of fluid assessment and Body Composition analysis including radioisotope dilution, underwater weighing and many more.. The Bodystat Quadscan 4000 Touch measures at 11 different frequencies ...
The measurement of total folate in clinical material became possible with the introduction of the Lactobacillus casei assay some 50 years ago. The use of lactoglobulin as a folate binding agent to measure folate by radioisotope dilution, later fluorimetry, is more user friendly but gives largely similar results.. The principal folate … ...
Science shouldnt be a term used loosely. It should, at minimum, be indicative of using a definitive method which includes observation, ask a question, form a hypothesis, analyze results, control groups, statistical methods, case study, and/or other avenues to come. ...
Isotope Dilution Mass Spectrometry (IDMS) has become an essential tool in research laboratories and is increasingly used in routine analysis labs (including environmental, food safety and clinical applications). This is the first textbook to present a comprehensive and instructive view of the theory and applications of this growing technique.The main objective of this book is to cover the theory and applications of Isotope Dilution in Analytical Chemistry. The scope is comprehensive to include elemental analysis, speciation analysis, organic analysis and biochemical and clinical analysis together with applications in metabolism studies and traceability of goods. Until now there have been no books published with the same general scope (only book chapters on particular applications). This is a textbook focused at post-graduate level covering the basic knowledge required for doctoral studies in this field. Isotope Dilution Mass Spectrometry will also outline practical applications of interest for routine
Isotope dilution analysis is a method of determining the quantity of chemical substances. In its most simple conception, the method of isotope dilution comprises the addition of known amounts of isotopically-enriched substance to the analyzed sample. Mixing of the isotopic standard with the sample effectively dilutes the isotopic enrichment of the standard and this forms the basis for the isotope dilution method. Isotope dilution is classified as a method of internal standardisation, because the standard (isotopically-enriched form of analyte) is added directly to the sample. In addition, unlike traditional analytical methods which rely on signal intensity, isotope dilution employs signal ratios. Owing to both of these advantages, the method of isotope dilution is regarded among chemistry measurement methods of the highest metrological standing. Analytical application of the radiotracer method is forerunner of isotope dilution. This method was developed in the early 20th century by George de ...
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If You Want to Get Rid of Warts Permanently from Your Body - Enter Here and Find Out How to Kill Warts with a Natural and Definitive Method
Crivellari, Stefano; Chiessi, Cristiano Mazur; Kuhnert, Henning; Häggi, Christoph; Portilho-Ramos, Rodrigo Costa; Zeng, Jing-Ying; Zhang, Yancheng; Schefuß, Enno; Mollenhauer, Gesine; Hefter, Jens; Alexandre, Felipe; Mulitza, Stefan; Sampaio, Gilvan (2018): HS1 records bases on isotope, inorganic and organic geochemistry of sediment cores GeoB16224-1 and GeoB16212-2. PANGAEA, https://doi.org/10.1594/PANGAEA.887797, Supplement to: Crivellari, S et al. (2018): Increased Amazon freshwater discharge during late Heinrich Stadial 1. Quaternary Science Reviews, 181, 144-155, https://doi.org/10.1016/j.quascirev.2017.12.005
Callaghan, D. (1969). Some investigations of intramolecular screening effects on 1H and 19F N.M.R. chemical shifts. PHD thesis, Aston University. Cliffe, K.R. (1969). Studies of deposition on cooled tubes with special reference to coal-fired boilers. PHD thesis, Aston University. Cole, I.M. (1969). An investigation of the rolling of cylindrical tube by grooved roll. PHD thesis, Aston University. Conceicao, P.H. (1969). A study of stray load losses in core clamp plates of salient pole synchronous machines. Masters thesis, Aston University. Cooksey, B.G. (1969). Substoichiometry in isotope dilution analysis:automation of the process with reference to mercury. PHD thesis, Aston University. Costello, J. (1969). Flow and transfer processes at abrupt expansions. PHD thesis, Aston University. ...
A method for measuring local venous flow by a constant indicator dilution technique is described. The optimal conditions have been outlined and the accuracy tested in vitro and found to be within ±3%. When compared with direct measurements of venous flow in dogs, its accuracy was within ±5%. The method is safe, easy to perform and, with the catheters described, flow can be measured over ranges of 20 to 5,700 ml/min in any vein greater than 4 mm inner diameter in which the catheter tips can be introduced.. ...
NEW ZEALAND - A researcher at the Geological and Nuclear Sciences (GNS) National Isotope Centre has developed a test based on isotope analysis to distinguish between battery (cage) barn, free-range and organic eggs based on the hens diet.
TQ-F (fluorescence tracer) - mobile discharge measurement System for turbulent rivers with unknown cross-section Profile by means of Tracer Dilution method.
Mass spectroscopy is increasingly used for measuring the presence and amounts of substances in samples, with applications in food, security, health and safety industries and is considered an excellent measurement tool. One of the methods used to identify multiple compounds in a sample is isotope dilution. However, this method does not account for the sample changes during the analysis and composition changes must be determined mathematically or by conducting multiple experiments. Due to this complexity, uptake of this advanced calibration approach is slow. Current algorithms to address simultaneous compound formation and degradation using multiple spiking isotope dilution mass spectrometry are extremely complex and do not result in explicit results nor reliable estimates of uncertainty in those results. Many algorithms give identical numerical results for the initial amount of substances in the sample, but the coefficients that describe the changes during the analysis differ.. There is a demand ...
Corrinoids from various ovine tissue samples (liver, blood, small intestinal fluid and faeces) were analysed using a combination of high-performance liquid chromatography (HPLC) and a radioisotope dilution assay (RIDA) to estimate the distribution of corrinoids - the cobalamins hydroxocobalamin (OH-cbl), methylcobalamin (me-cbl) and 5-deoxyadenosylcobalamin (ado-cbl), and cobalamin analogues - in these tissues. Samples were taken from either cobalt-deficient or cobalt-replete ewes, and ruminant and pre-ruminant lambs. In liver, ado-cbl predominated, followed by analogues, OH-cbl and me-cbl. Supplementation with either cobalt (ruminant) or vitamin B12 injections (pre-ruminant) increased the amount of ado-cbl and decreased analogues. In blood, OH-cbl predominated, followed by ado-cbl, analogues and me-cbl, respectively. In small intestinal fluid, the distribution from largest to smallest percentage was analogues, ado-cbl, OH-cbl and me-cbl. In faeces, analogues constituted the greatest proportion,
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1. Rat thymus cells were incubated in homologous serum (10%) and medium 199. The effects of various quantities of thymidine or deoxycytidine (0-30μm) on the radioactive labelling of cells with the corresponding radioactive deoxynucleoside were examined. From plots of the reciprocal of the radioactivity incorporated against the total deoxynucleoside concentration (`isotope-dilution plots), values were obtained for (a) the Vmax. of the rate-limiting step governing incorporation of the deoxynucleoside, and (b) the concentration of the pool of compounds competing with the radioactive deoxynucleoside at that rate-limiting step. From changes in these values under different experimental conditions inferences were drawn on the position and control of the rate-limiting step within intact cells. 2. Isotope-dilution plots for deoxycytidine were linear, whereas plots for thymidine were bimodal, indicating an abrupt increase in both the Vmax. and pool concentration at a critical thymidine concentration ...
Tracking cardiac output by a saline dilution technique using esophageal catheter electrodes.: This paper presents preliminary results of a study in which saline
Pleasure Convenient is a clever smash-up of styles. At just over two minutes the track is primarily interested in an old-school d-beat attack with plenty of playing Guitar Hero on expert level drum fills. But no track on Isotope is merely how it begins. Like most of the compositions across this record, subtle complexity pops up like Punxsutawney Phil trying not to see his shadow after a long night of consuming way too much sweet vermouth on the rocks with a twist. As the track decays into a marching rhythm, heavy on the snare, a syncopated rhythm needles through the fracas to take center stage. Although brief, its a revealing look into the sheer breadth of influences that ended up being honored in a band that started out with the goal of sounding like ultimate Japanese old school band Bastard.. Rolling out with all the groove and authority of a Tragedy track, Bloody Dove of Peace represents a convergence of styles. The rhythm section bursts forward, coming off a roll on the toms to end the ...
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Category:Radioisotope fuels See also: Radioisotope thermoelectric generator Radioisotope heater unit Radioisotope piezoelectric generator Thermionic converter
P32 and other tracer studies of eye information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.
The study of blood-tissue exchange by the multiple indicator dilution technique often needs frequent sampling in the blood of the indicator dilution curves (IDC). Usually, this requires the use of a catheter supported by a pump. This causes a distortion in the IDC, which must be removed for proper interpretation of the data. A deconvolution-based methodology to remove IDC distortion is presented. First, the catheter impulse response is modelled by means of data obtained from a suitable experiment. Then the reconstruction of the blood IDC is tackled by a new nonparametric deconvolution algorithm, which provides (quasi) time-continuous signals and exploits statistically based criteria for the choice of the regularisation parameter. The methodology is applied to the removal of cathether distortion in studies of glucose blood-tissue exchange in the human forearm and myocardium.. ...
Strong distinctions in metabolite concentrations were found with the quantification strategies applied. For dilutions ranging from 1:2 to 1:20 internal calibration and isotope dilution mass spectrometry were found to be most suitable for the compensation of matrix effects. Further more, the results showed that U13C4-aspartate as internal standard could be used for various amino acids in the chromatographic run. Using isotope dilution, where each metabolite has its own labelled analogue, the linear range of the calibration curve and the coefficient of correlation (up to 0.9999) were improved. The procedure of standard addition was only necessary for very low concentrated metabolites. To avoid this time consuming procedure, samples can as well be concentrated and measured via internal calibration instead. External calibration was sufficient for biological samples in dilutions of 1:20 or higher, because the measurements were hardly influenced by matrix effects. ...
12(S)-HETE-d8, Deuterium Conjugated/Tagged from Cayman Chemical,12(S)-HETE-d8 is used as an internal standard for the quantification of 12(S)-HETE by stable isotope dilution mass spectrometry.,biological,biology supply,biology supplies,biology product
Converts the newer IDMS (isotope dilution mass spectrometry) serum creatinine assay to the older, conventional assay (eg, alkaline picrate).
Mangerich A., Veith S., Popp O., Fahrer J., Martello R., Bohr V.A., Bürkle A. (2012) Quantitative analysis of WRN exonuclease activity by isotope dilution mass spectrometry, Mechanisms of Ageing and Development, 133, 575-579 Nikolova T., Hennekes F., Bhatti A., Kaina B. (2012) Chloroethylnitrosourea-induced cell death and genotoxicity: cell cycle dependence and the role of DNA double-strand breaks, HR and NHEJ, Cell Cycle, 11, 2606-2619 Lillich M., Che X., Weil T., Barth H., Fahrer J. (2012) Streptavidin-conjugated C3 protein mediates the delivery of mono-biotinylated RNAse A into macrophages, Bioconjugate Chemistry, 23, 1426-1436 Meise R., Tomicic M.T., Kaina B., Christmann M. (2012) The chloroethylating anticancer drug ACNU induces FRA1 that is involved in drug resistance of glioma cells, Biochimica et Biophysica Acta, 1823, 1199-1207 Bauer M., Goldstein M., Heylmann D., Kaina B. (2012) Human monocytes undergo excessive apoptosis following temozolomide activating the ATM/ATR pathway while ...
Corcho Alvarado, J. A., R. Purtschert, J. Rüedi, H. H. Loosli, C. Chabault, F. Barbecot, L. Dever, W. Aeschbach-Hertig, R. Kipfer, 2003. Origin and temporal evolution of the groundwater in the Fontainebleau Sands Aquifer (France) investigated using 3H, 85Kr, 39Ar, 14C and stable noble gases. International Symposium on Isotope Hydrology and Integrated Water Resources Management, IAEA, Vienna, IAEA-CN-104/92: 105-106. ...
An important additional and evolving use of radioisotopes is in the treatment of disease.. There is a fundamental belief that cancer, leukemia, heart disease, Parkinsons disease, and more can be treated-and possibly cured-through the use of molecules that seek and attach radioisotopes to tumors and cancerous growths. Through this process, radioactivity can be delivered directly to the cells that require treatment, with minimal damage to nearby tissue.. NorthStar is well-positioned to meet the challenges ahead.. ...
We discussed previously the impact of high costs for preclinical systems on the global drug development research market. We saw that there is opportunity to
Knowledge about cycling of N is the basis for management decisions in order to maintain crop productivity, reduce dependency on N fertilizers, and reduce the negative impact of agriculture on the environment. Research was conducted in the field during three growing seasons using 15N isotope dilution techniques to study the intensity of N cycling in an alfalfa (Medicago sativa L.)-meadow bromegrass (Bromus riparius Rhem.) mixture managed as a hay crop. In addition, two greenhouse experiments were conducted to compare short-term and long-term N transfer from bromegrass to alfalfa and vice versa. Nitrogen removed by hay harvest amounted to 171 and 32 kg ha$\sp{-1}\ yr\sp{-1}$ for alfalfa and bromegrass, respectively. The average accumulation of N in stubble + roots to 30 cm depth was 115 kg ha-1 for alfalfa and 73 kg ha-1 for bromegrass. Alfalfa derived 210 kg N ha$\sp{-1}\ yr\sp{-1}$ from the atmosphere. At least 31% of this fixed-N was accumulated in stubble + roots. Most of the N (59 to 74%) of ...
It is possible that oxidatively damaged DNA which arises as a result of radiotherapy may be involved in the therapeutic effect of the ionizing radiation and in the side effects. Therefore, for the first time, the broad spectrum of oxidatively damaged DNA biomarkers: urinary excretion of 8-oxodG (8-oxo-7,8-dihydro-2-deoxyguanosine), 8-oxoGua (8-oxo-7,8-dihydroguanine) as well as the level of oxidatively damaged DNA in leukocytes, was analyzed in head and neck cancer patients (n = 27) undergoing fractionated radiotherapy using methodologies which involve HPLC (high-performance liquid chromatography) prepurification followed by gas chromatography with isotope dilution mass spectrometry detection and HPLC/EC. Of all the analyzed parameters in the majority of patients, only urinary excretion of the modified nucleoside significantly increased over the initial level in the samples collected 24 hr after the last fraction. However, for the distinct subpopulation of 10 patients, a significant increase in ...
A double indicator dilution technique for determining the mean cross-sectional area (CSA) of a blood vessel in vivo is presented. Analogous to the thermodilution method, dilution of hypertonic saline was measured by an electrical conductance technique. Because the change in conductance rather than absolute conductance was used to calculate CSA, pulsatile changes in shear rate of blood and conductance of surrounding tissues had no effect on the data. To calculate CSA from an ion mass balance, cardiac output was needed and estimated from the thermodilution curve using the same cold (hypertonic) saline injection. The mean CSA, obtained from this double indicator dilution method (CSA(GD)), was compared with the CSA obtained from the intravascular ultrasound method (IVUS) in 44 paired observations in six piglets. The regression line is close to the line of identity (CSA(GD) = -1.83 + 1.06 · CSA(IVUS), r = 0.96). The difference between both CSAs was independent of the diameter of the vessel, on ...
Aridity and seasonality of precipitation are characteristics of the highland region in Bolivia. Groundwater becomes an important and safe source of water when surficial bodies are intermittent and affected by natural and anthropogenic contamination. Decades of exploitation of the Challapampa aquifer, combined with lack of information required to understand the groundwater circulation, represent a challenge for reservoir management. This study analyzes isotopic compositions of deuterium and oxygen-18 in different stages in the hydrologic cycle to assess flow patterns in the aquifer, especially in the alluvial fan of River Paria, where records are more extensive in space and time. Interpretations are based on existing and new data. Some implications, such as the age of water, the evaporation effect in groundwater and some thermal intrusions are supported by stable isotopes, tritium, radiocarbon, and electrical conductivity records. New results confirm that modern precipitation over the mountains
In most current designs of D-T fusion reactor blankets employing ceramic breeder materials, the use of a helium sweep gas containing 0.1 % of hydrogen is contemplated to extract tritium efficiently via isotopic exchange reactions. However, the isotope exchange reaction proceeds fast only at the more elevated temperatures, so that the rate of isotope exchange reactions is considerably low at lower temperatures. Taking into consideration that there is a broad temperature distribution within a blanket module, it is anticipated that the tritium bred in regions of lower temperatures will be poorly recovered. For this reason, there is still a need to develop techniques that contribute to the acceleration of the recovery of bred tritium at lower temperatures. In our previous works, the effect of catalytic active metal additives, such as Pt and Pd, on the heterogeneous isotope exchange reactions at the breeder-sweep gas interface was examined. The results indicate that the exchange reactions were ...
New strategies are needed to address the current and future shortages of radioisotopes that threaten medical research and treatment.
Keywords: Gross N biotransformation, soil microbial biomass, nitrogen availability, mineralisation, C:N ratios.. Summary:. Understanding the factors that govern microbial activities in soils is important, because the heterotrophic soil microbial biomass is driving the carbon (C) and nitrogen (N) cycling, and the net availability of N for plant uptake or losses. The processes by which C and N interact during decomposition of organic matter in soil, and the mineralisation-immobilisation turnover are well known but still difficult to predict, due to the complex interactions between soil micro-organisms and their substrates. The 15N isotope dilution techniques that allow rates of N transformations to be quantified accurately and simultaneously help the understanding of the effects of soil, crop and management conditions on microbial activities. The quantification of the relative importance of gross mineralisation, immobilisation and nitrification is also a key for understanding the competition ...
Keywords: Gross N biotransformation, soil microbial biomass, nitrogen availability, mineralisation, C:N ratios.. Summary:. Understanding the factors that govern microbial activities in soils is important, because the heterotrophic soil microbial biomass is driving the carbon (C) and nitrogen (N) cycling, and the net availability of N for plant uptake or losses. The processes by which C and N interact during decomposition of organic matter in soil, and the mineralisation-immobilisation turnover are well known but still difficult to predict, due to the complex interactions between soil micro-organisms and their substrates. The 15N isotope dilution techniques that allow rates of N transformations to be quantified accurately and simultaneously help the understanding of the effects of soil, crop and management conditions on microbial activities. The quantification of the relative importance of gross mineralisation, immobilisation and nitrification is also a key for understanding the competition ...
Iron is an essential element for the living organisms but free iron can be toxic. Iron metabolism disorders affect a large portion of human population. There exists a need for development of a reference technique to measure body iron stores. The ideal technique for determination of body iron stores would to measure ferritin concentration along with ferritin iron saturation. This study uses the principle of Isotope Dilution Mass Spectrometry (IDMS) to measure serum ferritin bound iron. IDMS requires the biosynthesis of a ferritin spike with isotopically enriched iron and sulphur. The aim of this project was to synthesize a ferritin spike for serum ferritin and ferritin bound iron quantification for development of a reference technique to determine body iron stores. This study involved the biosynthesis of a ferritin spike labelled with isotopic iron and sulphur ...
BioAssay record AID 772012 submitted by ChEMBL: Antifungal activity against Candida albicans NRRL Y-477 after 48 hrs by two-fold serial dilution technique.
A multi-point method of determining a time-zero blood volume by the tracer dilution technique. A tracer is injected into the blood stream of a living being, and a plurality of mixed samples of blood and tracer are removed from the blood stream at a corresponding plurality of measured time intervals subsequent to the injecting step. A blood portion volume corresponding to each time interval is automatically determined from the tracer level in the mixed samples, and a time-zero blood portion volume is automatically calculated from the determined blood portion volumes and time intervals.
FIELD OF SPECIALIZATION : Taxonomy of Angiosperms. SPECIAL INTEREST : Plant Anatomy, Medicinal & Ornamental Plants.. PRESENTLY WORKING ON FAMILY / TRIBE / GENUS OR FLORA OF (AREA): : Floristic Diversity of Wan Wildlife Sanctuary. PHONE : 020-29707072/020-29707078. E-MAIL : priyanka[at]bsi[dot]gov[dot]in,priyaingalkar[at]gmail[dot]com ON GOING OTHER PROJECTS: Flora of India vol. 24 (Families Urticaceae to Ceratophyllaceae). LIST OF PUBLICATIONS: A. Research articles/papers: 1. Priyanka Ingle. 2019. Pharmacognostic Investigations of Terminalia catappa L. Bioinfolet, 16(3): 168-175.. 2. Shantanu Chavan, R. Taur and P. Ingle. 2019. Note on distribution of Alysicarpus longifolius (Rottl. ex Spreng.) Wight & Arn. var. major Pokle in India. Plantae Scientia, 2(2): 29 - 31.. 3. Ughade, B. R., V.C. Khillare, D.M. Sangale, G. A. Korhale, P. Ingle, A.E. Tathe, R. Patil and G.D. Khedkar. 2018. A definitive method for distinguishing cultivated onion from its weedy mimic, Asphodelus fistulosus, at multiple ...
Gelatin Finings are used to clear beer before kegging or bottling. Gelatin is the most powerful organic fining agent available in brewing.. Note: Gelatin is not vegetarian. If you plan to serve your beer to vegetarian friends, do not use Gelatin finings!. Across the Internet on the various brewing forums there is a massive amount of conflicting opinion on the correct way to use gelatin finings. One of the main things that people get wrong, is they boil the gelatin before adding it to the beer. Boiling gelatin will render it useless; do NOT boil the gelatin finings before adding them to the beer! I hope to clear things up here with a definitive method to using gelatin finings to clear a 5 gallon batch of beer. This is a tried and tested method which I have used for many brews with great success.. ...
Learning Outcomes : At the end of this lesson, a student is able to : i. define radioisotopes ii. name examples of radioisotopes iii. describe applications of radioisotopes [ Click Radioisotopes to download powerpoint show]
The SNMMI Targeted Radioisotope Therapy (TRT) Working Group is very pleased to present their first webinar series on targeted radioisotope therapies for non-nuclear medicine physicians. This webinar series consists of 6 webinars, each focused on a specific disease area. Each webinar offers participants free CME.. ...
TO ANALYSE MATERIALS AND ARTICLES IN CONTACT WITH FOOD USING THE TECHNIQUE OF ISOTOPE DILUTION GC-MS AND TO ANALYSE THE FOOD IN CONTACT WITH THESE MATERIALS TO ASSESS THE MIGRATION OF BENZENE INTO FOOD ...
Use of radioisotopes in dating. To be able to distinguish the relative ages of rocks from such old material, and to get a better time resolution than that available from long-lived isotopes, short-lived isotopes that are no longer present in the rock can be used.
... radioisotope dilution technique MeSH E01.370.384.720 - radioligand assay MeSH E01.370.384.730 - radionuclide imaging MeSH ... fluorescent antibody technique, direct MeSH E01.450.495.225.230 - fluorescent antibody technique, indirect MeSH E01.450.495.225 ... enzyme multiplied immunoassay technique MeSH E01.450.495.410.380 - immunosorbent techniques MeSH E01.450.495.410.380.200 - ... glucose clamp technique MeSH E01.450.150.100.355 - glucose tolerance test MeSH E01.450.150.100.450 - lactose tolerance test ...
Currently, radioisotope dilution assay (RIDA) with labelled vitamin B12 and hog IF (pigs) have been used to determine vitamin ... To get a reliable reading of B12 content, more advanced techniques are available. One such technique involves pre-separation by ... The microbiological assay has been the most commonly used assay technique for foods, utilizing certain vitamin B12-requiring ...
Techniques using mass spectrometry and a double spike isotope dilution have been used for K-Ca age dating. ( ) - Uncertainty (1 ... The most stable artificial radioisotopes are 45Ca with a half-life of 163 days and 47Ca with a half-life of 4.5 days. All other ...
A technique similar to radioisotopic labeling is radiometric dating: using the known half-life of an unstable element, one can ... Scientists estimate that the elements that occur naturally on Earth (some only as radioisotopes) occur as 339 isotopes ( ... Isotopes are commonly used to determine the concentration of various elements or substances using the isotope dilution method, ... Some isotopes/nuclides are radioactive, and are therefore referred to as radioisotopes or radionuclides, whereas others have ...
Total Blood Volume can be measured manually via the Dual Isotope or Dual Tracer Technique, a classic technique, available since ... It is able to report Total Blood Volume (TBV), Plasma Volume (PV) and Red Cell Volume (RCV) using the indicator dilution ... Park, Junki; Puri, Sonika; Mattoo, Aditya; Modersitzki, Frank; Goldfarb, David (2012). "Radioisotope Blood Volume Measurement ... With this technique, a small volume of pure CO gas is inhaled and rebreathed for a few minutes. During rebreathing, CO binds to ...
Video-assisted thoracoscopic lung biopsy is the most definitive technique, but transbronchial biopsy has a yield of over 50% ... often peripheral collections of radioisotope."[citation needed] LAM and AML lesions do not typically exhibit increased uptake ... of predicted determined with gas dilution methods, suggesting significant air trapping in noncommunicating airspaces. ...
In this technique, one or more of the atoms of the molecule of interest is substituted for an atom of the same chemical element ... While radioisotopes had been used in human nutrition research for several decades prior, stable isotopes presented a safer ... Uses of radionuclides Radioactivity in biology Radioactive tracer Isotopomer Isotopologue Isobaric labeling Isotope dilution ... Any technique in measuring the difference between isotopomers can be used. The two primary methods, nuclear magnetic resonance ...
In this technique the number of viral plaques formed by a viral inoculum is counted, from which the actual virus concentration ... Sometimes the concentration of the analyte is too large and in that case the assay may involve sample dilution or some sort of ... Radioisotope labeled substrates as used in radioimmunoassays and equilibrium dialysis assays and can be detected by the ... A wide range of cellular secretions (say, a specific antibody or cytokine) can be detected using the ELISA technique. The ...
The technique uses lasers tuned to frequencies that ionize 235U atoms and no others. The positively charged 235U ions are then ... Enhancement of the centrifugal forces is achieved by dilution of UF6 with hydrogen or helium as a carrier gas achieving a much ... "Feasibility of Eliminating the Use of Highly Enriched Uranium in the Production of Medical Radioisotopes". Science & Global ... Gas centrifuge techniques produce close to 100% of the world's enriched uranium. The Zippe centrifuge is an improvement on the ...
Other techniquesEdit. Aerodynamic processesEdit. Schematic diagram of an aerodynamic nozzle. Many thousands of these small ... Enhancement of the centrifugal forces is achieved by dilution of UF6 with hydrogen or helium as a carrier gas achieving a much ... "Feasibility of Eliminating the Use of Highly Enriched Uranium in the Production of Medical Radioisotopes". Science & Global ... Diffusion techniquesEdit. Gaseous diffusionEdit. Main article: Gaseous diffusion. Gaseous diffusion is a technology used to ...
Techniques appropriate for a fixed cross-section of flow in a pipe are not useful in open channels. Measuring flow in waterways ... The dilution rate equals the flow rate. Acoustic Doppler velocimetry (ADV) is designed to record instantaneous velocity ... tracer methods may be used to deduce the flow rate from the change in concentration of a dye or radioisotope. Both gas and ... Likewise, sonar flow measurement uses the same techniques and algorithms employed in underwater acoustics, but applies them to ...
Isotope labeling measuring techniquesEdit. Any technique in measuring the difference between isotopomers can be used. The two ... In soil science 15N tracers are used extensively to study nitrogen cycling, whereas 13C and 14C, stable and radioisotopes of ... Isotope dilution. *Infrared spectroscopy of metal carbonyls. *Localization of organelle proteins by isotope method tagging ... 2018). Assessment of Zinc Metabolism in Humans Using Stable Zinc Isotope Techniques. Vienna: IAEA. ISBN 978-92-0-108418-7. . ...
Thirty radioisotopes have been characterised, which range in mass number from 209 to 238. After 232Th, the most stable of them ... This method relied on the specifics of the technique and the concentrate grain size; many alternatives have been proposed, but ... followed by selective precipitation by dilution with water, as on the subsequent steps. ... These rely on the fact that 232Th is a primordial radioisotope, but 230Th only occurs as an intermediate decay product in the ...
"Radioisotope Brief: Cesium-137 (Cs-137)". Emergency Preparedness and Response. United States: Centers for Disease Control and ... Further, some coastal areas might have less-favorable dilution or sedimentation characteristics than those observed so far. ... The authors concluded "We suggest an innovative statistical technique to determine the municipality-specific average exposed ... People can mitigate their exposure to radiation through a variety of protection techniques. DOE and NNSA aerial survey of the ...
"Radioisotope Dilution Technique" by people in this website by year, and whether "Radioisotope Dilution Technique" was a major ... Radioisotope Dilution Technique*Radioisotope Dilution Technique. *Dilution Technique, Radioisotope. *Dilution Techniques, ... "Radioisotope Dilution Technique" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Radioisotope Dilution Technique" by people in Profiles. ...
Radioisotope Dilution Technique * Reference Values * Sex Factors Substances * Carbon Radioisotopes * Hydrocortisone Grant ... by isotope dilution or by tetrahydro metabolite excretion) was weight-invariant in both sexes. The geometric mean of cortisol ... and was measured by isotope dilution (after 14C tracers) in 26 of the women and 23 of the men. The relationship of both ...
Phosphorus Radioisotopes * Radioisotope Dilution Technique Substances * Phosphates * Phosphatidylinositol Phosphates * ...
A reliable isotope dilution method for simultaneous determination of fumonisin B1, fumonisin B2 and fumonisin B3 in traditional ... Radioisotope Dilution Technique*. Tandem Mass Spectrometry / instrumentation, methods*. Chemical. Reg. No./Substance: 0/ ... A reliable isotope dilution method for simultaneous determination of fumonisins B1, B2 and B3 in traditional Chinese medicines ... A reliable isotope dilution method for simultaneous determination of fumonisin B1, fumonisin B2 and fumonisin B3 in traditional ...
Radioisotope Dilution Technique. *Rats. *Rats, Wistar. *Reference Values. *Tritium. Join CureHunter, for free Research ...
This agrees with the results of animal studies using radioisotope and particle dilution techniques.2 ,16 Diurnal variations in ... PRINCIPLES AND TECHNIQUE OF LASER DOPPLER FLOWMETRY. A DRT4 laser Doppler flowmeter (Moor Instruments, Devon, UK) was used, ... One report describing the methodological aspects of the technique7was limited to the study of older patients with a variety of ... AIMS To determine optimal measurement criteria and validate this technique as a measure of level of activity of extrinsic ...
This may be measured by one of several techniques including indicator dilution or use of radioisotopes. ...
Casey P J, Speckman K R, Ebert F J and Hobbs W E 1982 Radioisotope dilution technique for the determination of vitamin B12 in ... Johansson E and Johansson H 1986 Determination of vitamin B12 in gruel by a radioisotope dilution assay. Int. J. Vit. Nutr. Res ... Stenman U H and Puutula-Räsänen L 1980 Comparison of serum B12 (cobalamin) determination by two isotope-dilution methods and by ...
Radioisotope Dilution Technique Heart Septal Defects Krypton Cineangiography Laboratory infection with chikungunya virus: a ...
... radioisotope dilution technique MeSH E01.370.384.720 - radioligand assay MeSH E01.370.384.730 - radionuclide imaging MeSH ... fluorescent antibody technique, direct MeSH E01.450.495.225.230 - fluorescent antibody technique, indirect MeSH E01.450.495.225 ... enzyme multiplied immunoassay technique MeSH E01.450.495.410.380 - immunosorbent techniques MeSH E01.450.495.410.380.200 - ... glucose clamp technique MeSH E01.450.150.100.355 - glucose tolerance test MeSH E01.450.150.100.450 - lactose tolerance test ...
1. Standard radioisotope dilution techniques employing [3H]water and [22Na]sodium chloride have been used to determine the ...
Casey, P.J.; Speckman, K.R.; Ebert, F.J.; Hobbs, W.E. Radioisotope dilution technique for determination of vitamin B12 in foods ... Radio isotope dilution assays with labeled vitamin B12 and hog IF are used [20]. Further advances are expected with the ...
Radioisotope Dilution Technique; Tyrosine; Yeasts ...
Currently, radioisotope dilution assay (RIDA) with labelled vitamin B12 and hog IF (pigs) have been used to determine vitamin ... To get a reliable reading of B12 content, more advanced techniques are available. One such technique involves pre-separation by ... The microbiological assay has been the most commonly used assay technique for foods, utilizing certain vitamin B12-requiring ...
Early studies documented intravascular volume depletion using radioisotope dilution techniques (1,2), but later studies used ...
Radioisotope dilution techniques for measurement of body composition in health and disease.. 1967 A P Morgan 외 2 명 Radiologic ... Adult, Body Composition, Extracellular Space, analysis, Female, Humans, Male, Methods, Middle Aged, Potassium, Radioisotope ...
On the theory of the indicator-dilution method for measurement of blood flow and volume. J Appl Physiol 1954;12:731-744. ... Different imaging techniques are now available to evaluate CBF, notably stable xenon CT and perfusion CT studies. Stable xenon ... Equations for measuring blood flow by external monitoring of radioisotopes. Circ Res 1965;16:309-321. ... Axel L. Tissue mean transit time from dynamic computed tomography by a simple deconvolution technique. Invest Radiol 1983;18:94 ...
Dilution Technique, Radioisotope Dilution Techniques, Radioisotope Radioisotope Dilution Technic Radioisotope Dilution Technics ... Dilution Technics, Radioisotope. Dilution Technique, Radioisotope. Dilution Techniques, Radioisotope. Radioisotope Dilution ... Radioisotope Dilution Technics, Radioisotope Dilution Technique, Radioisotope Dilution Techniques, Radioisotope Dilution ... Radioisotope Dilution. Technics, Radioisotope Dilution. Technique, Radioisotope Dilution. Techniques, Radioisotope Dilution. ...
"Radioisotope Dilution Technique", "type": "DefinedTerm" }, { "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", "name": " ... Radioisotope Dilution Technique 118. ″ rdf:type schema:DefinedTerm 119. Nf521f7c294384d2e92d9696a1f889b36 schema: ...
Radioisotope Dilution Technique. Rats. Rats, Wistar. Tritium. Note générale:. In Vitro. Journal Article. ...
Radioisotope Dilution Technique. Scintiphotography. Rest. Related Feeds. Cardiology Journals. Discover the latest cardiology ... Possibilities, limitations, and technique for the study of regional myocardial perfusion in man by Xenon-133. (opens in new tab ... Measurement of blood flow in the right and left coronary artery beds in humans and dogs using the 133Xenon technique. ... Assessment of regional myocardial blood flow using the inert gas washout technique. ...
Radioisotope Dilution Technique. Note générale:. Comparative Study. Journal Article. Langue:. Anglais. Identificateurs:. urn: ... Comparison of the effects of chemical and isotopic dilution on the dissociation of bound labeled ligands.. ... Comparison of the effects of chemical and isotopic dilution on the dissociation of bound labeled ligands. ...
Radioisotope Dilution Technique. *Saccharomyces cerevisiae/genetics*. *Tritium. *Uracil/metabolism. Substances. *DNA, Fungal ...
Radioisotope Dilution Technique. *Time Factors. *Tritium. Substances. *Blood Glucose. *Carbon Radioisotopes. *Dietary ...
Radioisotope Dilution Technique MeSH DeCS ID:. 1851 Unique ID:. D001826 Documents indexed in the Virtual Health Library (VHL): ...
Variations on this technique include ELISA and Western blotting. The principle is also now employed with certain types of ... The amount of radioisotope discarded must be documented for both liquid and solid waste. Leakage or spills of radioactive ... The titre is the reciprocal of the highest dilution of sample that gives a positive (detectable) result. Positive immunoassay ... The amount of radioisotope discarded must be documented for both liquid and solid waste. Leakage or spills of radioactive ...
50] Meier P., Zierler K.L. On the Theory of the Indicator-Dilution Method for Measurement of Blood Flow and Volume. Journal of ... 96] Zierler K.L. Equations for Measuring Blood Flow by External Monitoring of Radioisotopes. Circulation Research 16: 309-321 ( ... 88] Wu O., Østergaard L., Weisskoff R.M., Benner T., Rosen B.R., Sorensen A.G. Tracer Arrival Timing-Insensitive Technique for ... The commonly used model for describing the DSC-MRI signal is based on the non diffusible tracer theory, also called dilution ...
Total body potassium (K) can be measured by whole-body counting of the naturally occurring radioisotope 40K. These techniques ... Water can be estimated by measuring the dilution volume of water labeled with stable-isotopes of hydrogen, 2H2O, or oxygen, H2 ... These techniques are simple and easy to perform and are well suited for field work or for large-scale studies. Sex-appropriate ... Commonly used techniques at the whole body level are anthropometric measurements of body weight, height, body circumferences, ...
Other radioisotope dilution assays (RIDA) have been developed and commercialized into kits, but the diagnostic credibility of ... One assay has been developed using a technique called differential radioassay (Herbert 1984;Herbert 1985). This procedure uses ... present in human plasma and can mask cobalamin deficiency because current radioisotope dilution. assays are not specific for ...
  • Absolute cortisol production was estimated from the urinary excretion of tetrahydro metabolites of cortisol in 74 healthy women varying in weight from 12% below to 218% above desirable weight, and in 37 healthy men varying in weight from 3% below to 139% above desirable weight, and was measured by isotope dilution (after 14C tracers) in 26 of the women and 23 of the men. (nih.gov)
  • Both absolute cortisol production and urinary creatinine excretion showed a significant positive linear correlation with relative weight in the men and women, but cortisol production/g urinary creatinine excretion (by isotope dilution or by tetrahydro metabolite excretion) was weight-invariant in both sexes. (nih.gov)
  • A reliable isotope dilution method for simultaneous determination of fumonisins B1, B2 and B3 in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry. (biomedsearch.com)
  • A reliable isotope dilution method for simultaneous determination of fumonisin B1, fumonisin B2 and fumonisin B3 in traditional Chinese medicines by ultra-high-performance LC-MS/MS was developed, and a special focus was placed on the optimization of extraction, cleanup, ultra-high-performance LC separation and MS/MS conditions. (biomedsearch.com)
  • These in vivo measurement techniques are commonly used to measure body burdens of iodine radioisotopes, but cannot be used to assess the stable isotope of iodine. (cdc.gov)
  • Isotope dilution determination for the trace level of 4(5)-methylimidazole in beverages using dispersive liquid-liquid microextraction coupled with ESI-HPLC-MS/MS. Food Chem. (harvard.edu)
  • Characterization and validation of an isotope-dilution LC-MS/MS method for quantification of total desmosine and isodesmosine in plasma and serum. (harvard.edu)
  • Modified method for determination of sulfur metabolites in plant tissues by stable isotope dilution-based liquid chromatography-electrospray ionization-tandem mass spectrometry. (harvard.edu)
  • Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution. (harvard.edu)
  • We report a new stable-isotope dilution method for rapid sequential analysis of TMA concentrations and the clinical and biochemical response to treatment with metronidazole. (semanticscholar.org)
  • All of these examples rely on a technique called Isotope Ratio Mass Spectrometry (IRMS) Click on one to learn more! (jerusalemroses.com)
  • Isotope effects are most readily observed in … Se-80 is used for the production of the medical radioisotope Br-80m. (jerusalemroses.com)
  • 1 relating to a radioisotope in pure form, free of dilution by stable isotope carriers. (thefreedictionary.com)
  • a term denoting a radioisotope of an element in pure form, i.e. essentially undiluted with a stable isotope carrier. (thefreedictionary.com)
  • Enriched refers to material that consists largely or exclusively of a single isotope and is usually obtained by one of the separation techniques described later in this chapter. (nap.edu)
  • The recent development of methods for in situ U-Pb age determination in carbonates has found widespread application, but the benefits and limitations of the method over bulk analysis isotope dilution - ID approaches have yet to be fully explored. (armapromsnab.ru)
  • In vivo measurement techniques are the most direct and widely used approach for assessing the burden of iodine radioisotopes within the body. (cdc.gov)
  • Radioisotope Dilution Technique" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
  • Indicator Dilution Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Casey P J, Speckman K R, Ebert F J and Hobbs W E 1982 Radioisotope dilution technique for the determination of vitamin B 12 in foods. (springer.com)
  • Jan. 2002) "Measurement of Total Body Water (TBW) Through In Vivo Dilution of Tracer Compounds: Use of D2O and its Determination by FT Infrared Spectroscopy" Annali diChimica 92:135-138. (patentgenius.com)
  • Recent years, however, have seen a revolution in the field with the emergence of in situ analysis techniques employing laser ablation inductively coupled plasma mass spectrometry LA-ICPMS and offering the prospect of direct determination of U-Pb ages on the scale of a few hundred microns. (armapromsnab.ru)
  • Combined use of fluorescence with a magnetic tracer and dilution effect upon sentinel node localization in a murine model. (ox.ac.uk)
  • This is the first in vivo study to assess the feasibility of combining the two most common novel techniques of using a magnetic tracer and indocyanine green (ICG) fluorescence. (ox.ac.uk)
  • 1 EDXRF of Used Automotive Catalytic Converters Energy Dispersive X-Ray Fluorescence (EDXRF) is a very powerful technique for measuring the concentration of elements in a sample. (docplayer.net)
  • Our studies (Hadjiev and Marinova, 1970) on the effects of intravenous administration of 50 mg of cocarboxylase on cerebral hemodynamics and metabolism in patients with vascular lesions of the brain, carried out by using the venous radioisotope dilution technique, showed a significant decrease in the lactacidosis of the jugular blood and irregular changes in the cerebral blood flow. (casafestival.org.uk)
  • AIMS To determine optimal measurement criteria and validate this technique as a measure of level of activity of extrinsic autonomic gut innervation. (bmj.com)
  • The in vivo measurement of these radioisotopes within the body is performed with various radiation detectors and associated electronic devices that are collectively known as in vivo thyroid monitors or whole body counters, depending on the body site of interest. (cdc.gov)
  • Radioisotope dilution techniques for measurement of body composition in health and disease. (naver.com)
  • Some observations of the degree of lateral and longitudinal dispersion which affect the general application of tracer techniques to river flow measurement will be presented. (osti.gov)
  • The basis of those estimates is the dilution principle in the measurement of total hepatic glucose production (HGP) and the transfer of label from substrate to the product, glucose. (physiology.org)
  • A new feature allows the use of TopCount for measuring a high energy beta emitter such as 32 P by Cerenkov counting, a well-known measurement technique that has the main advantage of not requiring the addition of scintillation cocktail. (bio-medicine.org)
  • The discovery of simple labeling procedures using radioisotopes, especially I125, allowed the use of radioimmunoassays for antigen measurement. (lsuhsc.edu)
  • Currently, the Positron Emission Tomography (PET) is the gold standard technique in functional imaging. (unipd.it)
  • 2.5 by positron emission tomography, cardiac magnetic resonance imaging, dilution methods, or intracoronary Doppler in the absence of coronary artery stenosis ≥50% or structural heart disease. (onlinejacc.org)
  • Currently, perfusion magnetic resonance using an exogenous tracer, such as gadolinium, is the most interesting technique for the quantitative study of the hemodynamic. (unipd.it)
  • The commonly used model for describing the DSC-MRI signal is based on the non diffusible tracer theory, also called dilution theory. (unipd.it)
  • Dilution of a tracer can also be used to estimate the total discharge. (britannica.com)
  • In the diagnostic technique known as radioimmunoassay (RIA), antigen is measured by its effect on the binding of a small quantity of radioactive tracer antigen to a predetermined amount of specific antibody. (google.com)
  • This RIA technique must include some procedure for separating antibody-bound tracer from the unbound tracer after completion of the immune reaction, whereby the radioactivity of the separated components can be determined by scintillation counting. (google.com)
  • Various procedures have been developed heretofor for separating the bound and unbound tracer components in RIA techniques. (google.com)
  • Comparison of plethysmographic and helium dilution lung volumes: which is best for COPD? (harvard.edu)
  • By mean the Helium dilution method they were examined in two different postures: that standing and squatting one. (eurekamag.com)
  • The purpose of this chapter is to describe the analytical methods that are available for detecting, measuring, and/or monitoring iodine and its radioisotopes, their metabolites, and other biomarkers of exposure and effect to iodine and its radioisotopes. (cdc.gov)
  • Early studies documented intravascular volume depletion using radioisotope dilution techniques ( 1 , 2 ), but later studies used less reliable clinical criteria-and all methods of estimating ECF and IVF volumes have significant caveats ( Table 1 ). (asnjournals.org)
  • Methods used to determine efficacy of treatment rely on invasive techniques such as tumor biopsies, or on detection of cytokines secreted by immune cells or proteins shed by tumor cells ( 3 ). (pnas.org)
  • 1. Body composition was assessed in 28 healthy subjects (body mass index 20-28 kg/m2) by dual-energy X-ray absorptiometry, deuterium dilution, densitometry, 40K counting and four prediction methods (skinfold thickness, bioelectrical impedance, near-i.r. interactance and body mass index). (nihr.ac.uk)
  • The ICR 8000 is able to obtain high throughput activity measurements for these and other channels and transporters by measuring the absolute concentrations of cytosolic and extracellular ions, a technique that is independent of, and complimentary to, methods that rely on voltage manipulation. (aurorabiomed.com)
  • 17-19 Direct solid mass spectrometry techniques have major advantages with respect to sample preparation: few sample preparation steps are required, and the risk of contamination is significantly lower. (spectroscopyeurope.com)
  • These techniques provide simple yet sensitive approaches to diagnosing damage to the central nervous system, brain injury and neuronal disorders using biological fluids. (google.ca)
  • These enriched stable isotopes are used as target materials in the preparation of radioisotopes with particle accelerators and nuclear reactors and as biological tracers in biomedical research and clinical applications. (nap.edu)
  • Cardiac output monitoring using indicator-dilution techniques: basics, limits, and perspectives. (harvard.edu)
  • Cardiac output units that measure the blood flow from the heart using the indicator dilution technique in which a radioisotope is injected upstream of the heart and monitored on the downstream side. (optometricmanagement.com)
  • These devices include a radioisotope detector and an electronic unit that processes the data from the detector and displays the cardiac output values. (optometricmanagement.com)
  • Instead, in vitro measurements provide an estimate of internally deposited iodine (both the stable and radioactive isotopes), utilizing techniques that measure iodine in body fluids, feces, or other human samples (Gautier 1983). (cdc.gov)
  • Different imaging techniques are now available to evaluate CBF, notably stable xenon CT and perfusion CT studies. (ajnr.org)
  • DI-fusion Comparison of the effects of chemical and isotopic dilution. (ac.be)
  • Comparison of the effects of chemical and isotopic dilution on the dissociation of bound labeled ligands. (ac.be)
  • Groups 3 and 4, the diluted injection groups, received an injection of magnetic tracers (Resovist and Sienna+, respectively) and saline for dilution. (ox.ac.uk)
  • Radial immunodiffusion, a variation of the agar precipitation technique, is used in clinical immunology for the detection and quantitation of all classes of immunoglobulins, complement, ceruplasmin, transferrin, and other serum components. (lsuhsc.edu)
  • In the assay plastic tubes coated with adrenal microsomes (100 micrograms/ml) were incubated with human sera diluted from 1:50 to 1:5000 and the retained antibodies detected by subsequent incubation with 125I-labelled protein A. The method was precise over the range of serum dilution of 1:250 to 1:5000. (biomedsearch.com)
  • 1. Standard radioisotope dilution techniques employing [ 3 H]water and [ 22 Na]sodium chloride have been used to determine the total body water and total exchangeable sodium of 20 male and 10 female normal Ghanaians (Africans) aged 19-25 years. (portlandpress.com)
  • For example, they can be used as specific immunoprecipitating reagents to detect the presence of the antigen which elicited the initial processing of the B cell genome by coupling this antigen-antibody reaction with suitable detection techniques such as labeling with radioisotopes or with enzymes capable of assay (RIA, EMIT, and ELISA). (justia.com)
  • Examples of these analytical techniques are given in NCRP Report No. 87 (1987) and are also listed in Table 7-1. (cdc.gov)
  • This radioisotope-free "combined technique" warrants further assessment within a clinical trial. (ox.ac.uk)
  • This information is provided without the need of complex clinical techniques like radioisotope dilution. (spassifieds.com)
  • In recent years a number of clinical diagnostic tests have been developed which employ radioisotope labeled materials. (google.com)
  • It is shown that the three approaches (stoichiometric, dilution, and combinatorial) are equivalent, provided the same set of assumptions are used. (physiology.org)
  • This may be measured by one of several techniques including indicator dilution or use of radioisotopes. (thefreedictionary.com)
  • This graph shows the total number of publications written about "Indicator Dilution Techniques" by people in Harvard Catalyst Profiles by year, and whether "Indicator Dilution Techniques" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Indicator Dilution Techniques" by people in Profiles. (harvard.edu)
  • Other investigators had monitored radioisotope uptake or equilibrium to measure ion fluxes and membrane potential and a limited number of studies, mostly in Gram-negative organisms, had seen some success using carbocyanine or oxonol fluorescent dyes to measure membrane potential, or loading bacteria with cell-permeant acetoxymethyl (AM) ester versions of ion-sensitive fluorescent indicator dyes. (jove.com)
  • It is for detecting, analyzing, and identifying proteins, similar to the western blot technique but differing in that protein samples are not separated electrophoretically but are spotted through circular templates directly onto the membrane. (abnova.com)
  • lactamase were randomized by in vitro techniques. (justia.com)
  • Dual-energy X-ray absorptiometry predicted three- and four-component model body composition slightly less well than densitometry or deuterium dilution (both of which greatly influence these multi-component models). (nihr.ac.uk)
  • Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security. (elsevier.com)
  • 6 In the gut, use of this technique has been limited to the study of perfusion in inflammatory or vascular diseases and to study anastomotic blood flow. (bmj.com)
  • Among imaging techniques affording evaluation of cerebral perfusion, perfusion CT studies involve sequential acquisition of cerebral CT sections obtained in an axial mode during the IV administration of iodinated contrast material. (ajnr.org)
  • However, in vitro perfusion techniques [10] provided that they simulate closely enough the in vivo conditions, do eliminate ethical and safety concerns as well as provide a simplified and well controlled experimental model. (scirp.org)
  • Overall, application of a variety of techniques permits detailed analysis of CKII phosphorylation sites on synthetic peptides that are model substrates. (cshl.edu)
  • Magnetic Resonance Imaging (MRI) is a medical imaging technique used in radiology to visualize the anatomical structures and the functions of the body. (unipd.it)
  • Second: Immunoglobulins can be complexed with other molecules such as radioisotopes or enzymes so that we can detect their binding to antigens at extremely low concentrations. (lsuhsc.edu)
  • In vivo measurements can be obtained through techniques that directly quantify internally-deposited iodine using, for example, thyroid or whole body counters. (cdc.gov)
  • Early work with radioisotopes showed that bacteria were actively metabolizing organic matter in the sea, but accurate measurements of growth rates and production were needed in order to quantify fully the role of bacteria in food chains and cycles of organic matter. (springer.com)
  • 2. From the precision of the basic measurements, the propagation of errors for the estimation of fat (+/- SD) by the four-component model was found to be +/- 0.54 kg, by the three-component model, +/- 0.49 kg, by deuterium dilution, +/- 0.62 kg, and by densitometry, +/- 0.78 kg. (nihr.ac.uk)
  • This application was developed to promote deeper understanding of the science of geochronology, including the integration of crystal-scale relative dating principles with numerical dating via radioisotope measurements. (carleton.edu)
  • Nevertheless, non-conducting solid samples can be directly analysed by using a radio frequency powered source, 21 with direct current device plasma using the secondary cathode technique 22,23 or by mixing the sample with a conducting host. (spectroscopyeurope.com)
  • Dot blot is a technique can be used as a semiqualitative method for rapid screening of a large number of samples. (abnova.com)
  • However, limitations in the use of radioisotopes have resulted in emergence of novel techniques. (ox.ac.uk)
  • In banana, several DNA marker techniques have been used to investigate genetic relationships between Musa accessions, and to determine differences in somaclonal variants and radiation-induced mutants. (fao.org)
  • The hybrids thus formed are segregated into single genetic strains by selection, dilution, and regrowth, and each strain thus represents a single genetic line. (justia.com)
  • A non-radioactive silver staining technique for AFLP markers suitable for local laboratory conditions has been established. (fao.org)
  • Students will use a similar technique in the activity and later in their laboratory session. (carleton.edu)
  • Immunoprecipitation (IP) is the technique of precipitating an protein antigen out of solution using an antibody specific to that antigen. (abnova.com)
  • 5. The results suggest that the three- and four-component models are not compromised by errors arising from individual techniques. (nihr.ac.uk)
  • More particularly, it concerns the use of rapid selection techniques to identify specific polypeptides having desirable characteristics out of large libraries of polypeptides. (justia.com)
  • 12 , 13 The possible application of this technique to study the neural regulation of the microcirculation, as opposed to the effects of inflammation or trauma, opens up a new means of studying functional disorders. (bmj.com)
  • In this report, the Cerenkov counting performance of the TopCount is documented for linearity, volume effects, efficiency, background and well-to-well crosstalk, as well as the applicability of this technique for liquid and filter/membrane counting. (bio-medicine.org)
  • A common challenge for physicians is the differential diagnosis between PC and CP, which is assumed to be a risk factor for PC development (2) , despite the availability of advanced endoscopic, radiological, and ultrasonographic techniques. (aacrjournals.org)
  • Nevertheless, it is concluded that these discordances between the radioisotope systems are likely due to changes in their decay rates in the past, with the longer half-life b-emitter 87 Rb being accelerated more and thus yielding an older "age. (answersingenesis.org)
  • In rocks , radioisotopes such as Uranium decay with half-lives of millions or even perhaps billions of. (armapromsnab.ru)
  • Six patients with moyamoya disease were diagnosed by cerebral angiogram, and STA-MCA anastomosis technique and EMS were done to reconstruct the rCBF. (go.jp)
  • Specifically, the invention relates to using recombinant techniques to produce both immunoglobulins which are analogous to those normally found in vertebrate systems and to take advantage of these gene modification techniques to construct chimeric or other modified forms. (justia.com)
  • Selenium isotopes are mainly used for the production of medical and industrial radioisotopes. (jerusalemroses.com)
  • Background: Sentinel node biopsy using radioisotope and blue dye remains a gold standard for axillary staging in breast cancer patients with low axillary burden. (ox.ac.uk)
  • Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. (elsevier.com)