Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Cottontail rabbit papillomavirus: The type species of KAPPAPAPILLOMAVIRUS. It is reported to occur naturally in cottontail rabbits in North America.Hemorrhagic Disease Virus, Rabbit: A species in the genus LAGOVIRUS which causes hemorrhagic disease, including hemorrhagic septicemia, in rabbits.Immune Sera: Serum that contains antibodies. It is obtained from an animal that has been immunized either by ANTIGEN injection or infection with microorganisms containing the antigen.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Cornea: The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)Cholesterol, Dietary: Cholesterol present in food, especially in animal products.Reticulocytes: Immature ERYTHROCYTES. In humans, these are ERYTHROID CELLS that have just undergone extrusion of their CELL NUCLEUS. They still contain some organelles that gradually decrease in number as the cells mature. RIBOSOMES are last to disappear. Certain staining techniques cause components of the ribosomes to precipitate into characteristic "reticulum" (not the same as the ENDOPLASMIC RETICULUM), hence the name reticulocytes.Kinetics: The rate dynamics in chemical or physical systems.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Muscles: Contractile tissue that produces movement in animals.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Molecular Weight: The sum of the weight of all the atoms in a molecule.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Cross Reactions: Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.Electrophoresis, Polyacrylamide Gel: Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Aqueous Humor: The clear, watery fluid which fills the anterior and posterior chambers of the eye. It has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens. (Cline et al., Dictionary of Visual Science, 4th ed, p319)Immunodiffusion: Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction.Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Microscopy, Electron: Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.Injections: Introduction of substances into the body using a needle and syringe.Vitreous Body: The transparent, semigelatinous substance that fills the cavity behind the CRYSTALLINE LENS of the EYE and in front of the RETINA. It is contained in a thin hyaloid membrane and forms about four fifths of the optic globe.Ileum: The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.Muscle, Smooth, Vascular: The nonstriated involuntary muscle tissue of blood vessels.Diet, Atherogenic: A diet that contributes to the development and acceleration of ATHEROGENESIS.Antibody Specificity: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Ciliary Body: A ring of tissue extending from the scleral spur to the ora serrata of the RETINA. It consists of the uveal portion and the epithelial portion. The ciliary muscle is in the uveal portion and the ciliary processes are in the epithelial portion.Aorta, Thoracic: The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Iris: The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.Antigen-Antibody Reactions: The processes triggered by interactions of ANTIBODIES with their ANTIGENS.Pseudopregnancy: An acyclic state that resembles PREGNANCY in that there is no ovarian cycle, ESTROUS CYCLE, or MENSTRUAL CYCLE. Unlike pregnancy, there is no EMBRYO IMPLANTATION. Pseudopregnancy can be experimentally induced to form DECIDUOMA in the UTERUS.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Ear: The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE.Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Immunoelectrophoresis: A technique that combines protein electrophoresis and double immunodiffusion. In this procedure proteins are first separated by gel electrophoresis (usually agarose), then made visible by immunodiffusion of specific antibodies. A distinct elliptical precipitin arc results for each protein detectable by the antisera.Administration, Topical: The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.Fluorescent Antibody Technique: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.Cholesterol: The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.Conjunctiva: The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball.Immunization: Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Kidney Cortex: The outer zone of the KIDNEY, beneath the capsule, consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Arteries: The vessels carrying blood away from the heart.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Epitopes: Sites on an antigen that interact with specific antibodies.Sodium: A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Epithelium: One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.Acetylcholine: A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.Chromatography, Gel: Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Muscle, Smooth: Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)Antigen-Antibody Complex: The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.gamma-Globulins: Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.Heart: The hollow, muscular organ that maintains the circulation of the blood.Potassium: An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.Sinoatrial Node: The small mass of modified cardiac muscle fibers located at the junction of the superior vena cava (VENA CAVA, SUPERIOR) and right atrium. Contraction impulses probably start in this node, spread over the atrium (HEART ATRIUM) and are then transmitted by the atrioventricular bundle (BUNDLE OF HIS) to the ventricle (HEART VENTRICLE).Electric Stimulation: Use of electric potential or currents to elicit biological responses.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Wound Healing: Restoration of integrity to traumatized tissue.Antigens: Substances that are recognized by the immune system and induce an immune reaction.Eye: The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.Fibroma Virus, Rabbit: A species of LEPORIPOXVIRUS causing subcutaneous localized swellings in rabbits, usually on the feet.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Myosins: A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.Psoas Muscles: A powerful flexor of the thigh at the hip joint (psoas major) and a weak flexor of the trunk and lumbar spinal column (psoas minor). Psoas is derived from the Greek "psoa", the plural meaning "muscles of the loin". It is a common site of infection manifesting as abscess (PSOAS ABSCESS). The psoas muscles and their fibers are also used frequently in experiments in muscle physiology.Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Treponema pallidum: The causative agent of venereal and non-venereal syphilis as well as yaws.Microvilli: Minute projections of cell membranes which greatly increase the surface area of the cell.Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Action Potentials: Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.Ophthalmic Solutions: Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.Radioimmunoassay: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.Animals, Newborn: Refers to animals in the period of time just after birth.Protein Biosynthesis: The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.Amino Acids: Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.Prostaglandins E: (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.Erythrocytes: Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.Peptide Fragments: Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Endothelium: A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.Keratitis, Dendritic: A form of herpetic keratitis characterized by the formation of small vesicles which break down and coalesce to form recurring dendritic ulcers, characteristically irregular, linear, branching, and ending in knoblike extremities. (Dictionary of Visual Science, 3d ed)Serum Albumin, Bovine: Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)Prostaglandins: A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes.Adenosine Triphosphate: An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Immunoglobulin Allotypes: Allelic variants of the immunoglobulin light chains (IMMUNOGLOBULIN LIGHT CHAINS) or heavy chains (IMMUNOGLOBULIN HEAVY CHAINS) encoded by ALLELES of IMMUNOGLOBULIN GENES.Retina: The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.Membrane Potentials: The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).Recombinant Proteins: Proteins prepared by recombinant DNA technology.Histocytochemistry: Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.Antigens, Bacterial: Substances elaborated by bacteria that have antigenic activity.Endothelium, Vascular: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.Vasoconstriction: The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Biological Transport: The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Blood Proteins: Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.Intraocular Pressure: The pressure of the fluids in the eye.Lacrimal Apparatus: The tear-forming and tear-conducting system which includes the lacrimal glands, eyelid margins, conjunctival sac, and the tear drainage system.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Endothelium, Corneal: Single layer of large flattened cells covering the surface of the cornea.Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Chromatography: Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts.Cell Membrane: The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Endotoxins: Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.Leukocytes: White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).Cell Line: Established cell cultures that have the potential to propagate indefinitely.Neutrophils: Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.Cartilage, Articular: A protective layer of firm, flexible cartilage over the articulating ends of bones. It provides a smooth surface for joint movement, protecting the ends of long bones from wear at points of contact.Chromatography, Affinity: A chromatographic technique that utilizes the ability of biological molecules to bind to certain ligands specifically and reversibly. It is used in protein biochemistry. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Culture Techniques: Methods of maintaining or growing biological materials in controlled laboratory conditions. These include the cultures of CELLS; TISSUES; organs; or embryo in vitro. Both animal and plant tissues may be cultured by a variety of methods. Cultures may derive from normal or abnormal tissues, and consist of a single cell type or mixed cell types.Antibodies, Anti-Idiotypic: Antibodies which react with the individual structural determinants (idiotopes) on the variable region of other antibodies.

Fitzgerald factor (high molecular weight kininogen) clotting activity in human plasma in health and disease in various animal plasmas. (1/50569)

Fitzgerald factor (high molecular weight kininogen) is an agent in normal human plasma that corrects the impaired in vitro surface-mediated plasma reactions of blood coagulation, fibrinolysis, and kinin generation observed in Fitzgerald trait plasma. To assess the possible pathophysiologic role of Fitzgerald factor, its titer was measured by a functional clot-promoting assay. Mean +/- SD in 42 normal adults was 0.99+/-0.25 units/ml, one unit being the activity in 1 ml of normal pooled plasma. No difference in titer was noted between normal men and women, during pregnancy, or after physical exercise. Fitzgerald factor activity was significantly reduced in the plasmas of eight patients with advanced hepatic cirrhosis (0.40+/-0.09 units/ml) and of ten patients with disseminated intravascular coagulation (0.60+/-0.30 units/ml), but was normal in plasmas of patients with other congenital clotting factor deficiencies, nephrotic syndrome, rheumatoid arthritis, systemic lupus erythematosus, or sarcoidosis, or under treatment with warfarin. The plasmas of 21 mammalian species tested appeared to contain Fitzgerald factor activity, but those of two avian, two repitilian, and one amphibian species did not correct the coagulant defect in Fitzgerald trait plasmas.  (+info)

Evidence suggesting the regulation of a coagulation factor levels in rabbits by a transferable plasma agent. (2/50569)

New Zealand white rabbits were given 30 ml of goat serum intravenously. This procedure resulted in an immediate decrease in platelet count, fibrinogen, and levels of coagulation factors II, V, VII, and X, due to consumption coagulopathy. These factors returned toward baseline levels approximately 12 hr after the injection. Plasma from rabbits who had received goat serum 48 hr previously (donor rabbits) was injected into recipient rabbits. This procedure resulted in a slight rise in the level of coagulation factor II (range, 20%-30%) and a significant rise in factors V (35%-75%), VII (35%-235%), and X (35%-75%) in the recipients. When plasma from control donor rabbits who had not received goat serum was injected into recipients, there was no change in these coagulation factors. It is postulated that the reduction in coagulation factor levels in donor rabbits induces a "coagulopoietin" for each factor or one "coagulopoietin" for all factors which stimulates increased synthesis and/or release of these factors in recipient rabbits.  (+info)

The indirect hemagglutination test for the detection of antibodies in cattle naturally infected mycoplasmas. (3/50569)

Stable mycoplasma antigens for the indirect hemagglutination test (IHA) were prepared employing glutaraldehyde treated sheep erythrocytes sensitized with Mycoplasma agalactiae subsp. bovis and Mycoplasma bovigenitalium antigens. Employing these antigens mycoplasma antibodies were detected in sera from cattle which had mastitic symptoms due to natural infection with either M. agalactiae subsp. bovis or M. bovigenitalium. A total of 200 cows from four herds were examined at varying intervals for the presence of M. agalactiae subsp. bovis and for the detection of antibody using growth inhibition and IHA tests. Mycoplasmas were isolated from 37 animals. Growth inhibiting antibody was detected from 56 of the 200 animals. In the IHA tests, antibody titer greater than or equal to 1:80 were detected in 148 animals, 76 of these having antibody titers greater than or equal to 1:160, while sera of 116 normal control animals had no growth inhibiting antibody and none had IHA antibody titers greater than 1:40. M. bovigenitalium was isolated from the milk of three of 26 animals in a fifth herd during an outbreak of mastitis. Growth inhibiting antibodies were demonstrated in the sera of ten of the 26 animals. However, the IHA test detected antibody titers of greater than or equal to 1:160 in 13 animals and of 1:80 in one of the 26 animals. To determine the specificity of the IHA tests, M. agalactiae subsp. bovis and M. bovigenitalium antigens were reacted with rabbit hyperimmune typing sera produced against 12 species of bovine mycoplasmatales. Homologous antisera showed IHA antibody titers of 1:1280 and 1:2560 against M. agalactiae subsp. bovis and M. bovigenitalium respectively, whereas heterologous antisera showed IHA antibody titers of less than or equal to 1:20. Also eight type-specific bovine antisera were reacted with M agalactiae subsp. bovis and M. bovigenitalium antigens in homologous and heterologous tests. Homoogous reactions showed IHA antibody titers greater than or equal to 1:320, whereas heterologous reactions showed IHA titers of less than or equal to 1:20. This IHA test promises to be useful for the detection of bovine mycoplasma antibodies in sera from cattle infected with M. agalactiae subsp. bovis or M. bovigenitalium. Thes test is sensitive, reproducible and specific and the technique is relatively simple and rapid. The antigens were stable for at least seven months.  (+info)

The effect of route of immunization on the lapine immune response to killed Pasteurella haemolytica and the influence of aerosol challenge with the live organism. (4/50569)

Appearance of anti-Pasteurella haemolytica antibody in the serum and broncho-alveolar washings of rabbits is independent of the route of immunization and is similar in both locations. The most influential factor in development of a humoral response is exposure to live P. haemolytica and prior exposure to the killed bacterium has no significant effect upon titre determined following aerosol challenge with live organisms.  (+info)

New perspectives on biliary atresia. (5/50569)

An investigation into the aetiology, diagnosis, and treatment of biliary atresia was carried out because the prognosis remains so poor.In an electron microscopical study no viral particles or viral inclusion bodies were seen, nor were any specific ultrastructural features observed. An animal experiment suggested that obstruction within the biliary tract of newborn rabbits could be produced by maternal intravenous injection of the bile acid lithocholic acid.A simple and atraumatic method of diagnosis was developed using(99) (m)Tc-labelled compounds which are excreted into bile. Two compounds, (99m)Tc-pyridoxylidene glutamate ((99m)Tc-PG) and (99m)Tc-dihydrothioctic acid ((99m)Tc-DHT) were first assessed in normal piglets and piglets with complete biliary obstruction. Intestinal imaging correlated with biliary tract patency, and the same correlation was found in jaundiced human adults, in whom the (99m)Tc-PG scan correctly determined biliary patency in 21 out of 24 cases. The (99m)Tc-PG scan compared well with liver biopsy and (131)I-Rose Bengal in the diagnosis of 11 infants with prolonged jaundice.A model of extrahepatic biliary atresia was developed in the newborn piglet so that different methods of bile drainage could be assessed. Priorities in biliary atresia lie in a better understanding of the aetiology and early diagnosis rather than in devising new bile drainage procedures.  (+info)

Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (6/50569)

We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved.  (+info)

Stimulation of renin release from rabbit renal cortex by arachidonic acid and prostaglandin endoperoxides. (7/50569)

The mechanism by which renal prostaglandins stimulate renin secretion in vivo is unknown. In this in vitro study we measured the effects of activation of the prostaglandin (PG) system on renin release from slices of rabbit renal cortex. The PG precursor arachidonic acid (C20:4), a natural PG endoperoxide (PGG2), two stable synthetic PG endoperoxide analogues (EPA I and II), PGE2, PGF2alpha, and two different PG synthesis inhibitors [indomethacin and 5,8,11,14-eicosatetraynoic acid (ETA)] were used to evaluate the possibility of a direct action of the cortical PG system on renin secretion. Renin release increased significantly with time after addition of C20:4, PGG2, EPA I, and EPA II to the incubation medium. Stimulation of renin release was se-related for C20:4 in concentrations of 0.6 to 4.5 X 10(-6) M, for EPA I in concentrations of 0.7 to 2.8 X 10(-6) M, and for EPA II in concentrations of 1.4 to 14.0 X 10(-6) M. Indomethacin (10(-4) M) and ETA (10(-4) M) significantly decreased basal renin release as well as the renin release stimulated by C20:4 and EPA I. PGE2(10(-12) to 10(-6) M) had no effect on renin release, whereas PGF2alpha (10(-12) to 10(-6) M) decreased renin release in a dose-dependent manner. These data raise the possibility of a direct action of the renal cortical PG system on renin secretion. The results further indicate that stimulation of renin release by C20:4 may depend more specifically on the action of PG endoperoxides than on the primary prostaglandins.  (+info)

Acute renal failure caused by nephrotoxins. (8/50569)

Renal micropuncture studies have greatly changed our views on the pathophysiology of acute renal failure caused by nephrotoxins. Formerly, this type of renal insufficiency was attributed to a direct effect of the nephrotoxins on tubule epithelial permeability. According to that theory, glomerular filtration was not greatly diminished, the filtrate formed being absorbed almost quantitatively and nonselectively across damaged tubule epithelium. Studies in a wide variety of rat models have now shown glomerular filtration to be reduced to a level which will inevitably cause renal failure in and of itself. Passive backflow of filtrate across tubular epithelium is either of minor degree or nonexistent even in models where frank tubular necrosis has occurred. This failure of filtration cannot be attributed to tubular obstruction since proximal tubule pressure is distinctly subnormal in most models studied. Instead, filtration failure appears best attributed to intrarenal hemodynamic alterations. While certain facts tend to incriminate the renin-angiotensin system as the cause of the hemodynamic aberrations, others argue to the contrary. The issue is underactive investigation.  (+info)

*Caliciviridae

Rabbit hemorrhagic disease virus (RHDV) is a pathogen of rabbits that causes major problems throughout the world where rabbits ... Australia and New Zealand, in an effort to control their rabbit populations, have intentionally spread calicivirus. Feline ... The Caliciviridae family includes the following genera: Genus Lagovirus; type species: Rabbit hemorrhagic disease virus Genus ... Diseases associated with this family include: feline calicivirus: respiratory disease; rabbit hemorrhagic disease virus: often- ...

*Calicivirin

Wirblich, C.; Sibilia, M.; Boniotti, M.B.; Rossi, C.; Thiel, H.J.; Meyers, G. (1995). "3C-like protease of rabbit hemorrhagic ... Martin Alonso, J.M.; Casais, R.; Boga, J.A.; Parra, F. (1996). "Processing of rabbit hemorrhagic disease virus polyprotein". J ... rabbit hemorrhagic disease virus 3C endopeptidase) is an enzyme. This enzyme catalyses the following chemical reaction ...

*Rabbit haemorrhagic disease

These young rabbits were therefore able to survive and breed rabbit numbers back up. Ten years on, rabbit populations (in the ... Flies, rabbit fleas, and mosquitoes can also spread the virus between rabbits. Climate appears to play a crucial role in the ... The European rabbit is the second most serious pest in New Zealand. Rabbits compete with livestock for grazing pasture, kill ... Surviving rabbits are quarantined or humanely euthanized. Test rabbits may be used to monitor the virus on vaccinated farms. ...

*American rabbit

"The American Rabbit". Slow Food USA. "The American Rabbit Breeders Association". ARBA. "American Rabbit Breed History". "Rabbit ... The American Rabbit is a breed of rabbit, recognized by the American Rabbit Breeders Association (ARBA) in 1917. By the ARBA ... This has led to an increased interest in the American Rabbit as a heritage or homestead rabbit breed. American Rabbit Breeders ... the European wild rabbit. The American Rabbit was originally accepted into the ARBA as a 'Blue' rabbit, and historically has ...

*Reticulocyte

Scientists can collect reticulocytes from animals such as rabbits and extract the mRNA and translation enzymes to study protein ... 67a] Protein synthesis with rabbit reticulocyte preparations. pp. 724-731. doi:10.1016/0076-6879(74)30069-9. For more ...

*Svendborg Rabbits

... is a Danish professional basketball team, from Svendborg. The home ground is 'The Rabbits House' (Kaninhulen ...

*Battle Rabbits

"Battle Rabbits". Seven Seas Entertainment. Retrieved 10 November 2015. バトラビッツ 02 (IDコミックス ZERO-SUMコミックス) [Battle Rabbits 02 (ID ... Anime and manga portal Battle Rabbits at Seven Seas Entertainment Battle Rabbits (manga) at Anime News Network's encyclopedia. ... Battle Rabbits (バトラビッツ, Bato Rabittsu) is a Japanese manga series written by Yuki Amemiya and Yukino Ichihara. The series is ... バトラビッツ 1巻 (IDコミックス ZERO-SUMコミックス) [Battle Rabbits Volume 1 (ID Comics ZERO-SUM Comics)]. Amazon.co.jp (in Japanese). Retrieved ...

*The Rabbits

... is a music theatre work with music by Kate Miller-Heidke and libretto by Lally Katz (with additional music by Iain ... The Rabbits was first performed at the Perth International Arts Festival in February 2015, produced by Opera Australia and ... "Rabbits let loose as Opera Australia's Lyndon Terracini opts for high drama" by Matthew Westwood, The Australian, 12 August ... As per the original book, it is an allegory for the colonisation of Australia, depicting an invasion of rabbits (in lieu of the ...

*Local Rabbits

"Local Rabbits This Is It Here We Go". Exclaim!, By James Keast Sep 01, 2002 "Local Rabbits, Inbreds Weeping Tile And Others ... "The return of the remarkably virile Local Rabbits",[dead link] Eye Weekly, April 16, 1998. Local Rabbits fan site. ... Local Rabbits were a Canadian alternative rock band based in Montreal, Quebec, active in the 1990s and early 2000s. The band ... Local Rabbits formed in 1990 when its members were teenagers. At first they performed covers of blues music. The band released ...

*Black Rabbits

... is the seventh studio album by Australian post-grunge band Grinspoon, which was released on 28 September 2012. ... Wykes, Sarah (14 September 2012). "Album Review: Grinspoon - Black Rabbits (2012 LP)". the AU review. Heath Media & the AU ... Sjostedt, Arne (22 November 2012). "Review of Grinspoon's Black Rabbits". The Sydney Morning Herald. Fairfax Media. Retrieved 8 ... Arne Sjostedt of The Sydney Morning Herald praised Black Rabbits as "a great release from a band who has managed to plug out ...

*The Rabbits' Wedding

The rabbits live in the forest, where they go on journeys. The black rabbit (male) feels conflicted; finally he reveals why he ... The white rabbit accepts the black rabbit's wish and love. A wedding is celebrated and the bunnies dance under the moonlight ... The Rabbits' Wedding was published on April 30, 1958, and depicted the love affair and wedding of two bunnies, one white and ... The Rabbits' Wedding is a children's picture book created and illustrated by American author and illustrator Garth Williams, ...

*Do Rabbits Wonder?

... is the first full-length album released by Whirlwind Heat, recorded and produced by Jack White of The White ... Do Rabbits Wonder? received generally positive reviews from music critics. At Metacritic, which assigns a normalized rating out ... "Reviews for Do Rabbits Wonder by Whirlwind Heat". Metacritic. CBS Interactive. Retrieved July 4, 2015. Phares, Heather. "Do ... Moon, Tom (May 1, 2003). "Recordings: Whirlwind Heat, Do Rabbits Wonder?, 3 Stars". Rolling Stone. Wenner Media. Archived from ...

*Dirty Little Rabbits

... are an American alternative rock band formed in 2007 in Johnston, Iowa. They are often referred to as a ... Dirty Little Rabbits continued to tour in 2008, with their own shows through February and May and in support of Mindless Self ... Crahan had previously worked with Fury on a band he was a part of in Denver, but recruited him for Dirty Little Rabbits. Around ... He describes Dirty Little Rabbits as the band he's been waiting his whole life for. He made a particular point about the fact ...

*Rabbits Foot Lodge

... is a historic house at 3600 Silent Grove Road in Springdale, Arkansas. Sited on 100 acres (40 ha) northwest ... "NRHP nomination for Rabbits Foot Lodge" (PDF). Arkansas Preservation. Retrieved 2015-04-22. http://www.arkansaspreservation.com ...

*Rabbits Foot Meadery

Rabbit's Foot Meadery has won numerous awards and is known throughout the industry as a leader and innovator. Rabbit's Foot ... Rabbit's Foot Meadery is a meadery and winery in Sunnyvale, California, United States. Rabbit's Foot Meadery was founded in ... Rabbit's Foot Meadery". meadist.com. Retrieved 28 August 2013. Jon Swaine (29 December 2010). "Mead popular again for first ...

*Seibu Prince Rabbits

They adopted the new name Seibu Prince Rabbits in 2006. The club also had a women's team called the Seibu Princess Rabbits. On ... The Seibu Prince Rabbits (SEIBUプリンス ラビッツ, Seibu Purinsu Rabittsu) were an Asia League Ice Hockey team based in Nishitōkyō City ... The Rabbits played at the DyDo Drinco Ice Arena from 2006-2009. In December 2008, Prince Hotels, the team's owner, announced ... Prince Rabbits going for one final crown in ALIH final アイスホッケー西武が解散、引受先見つからず (Japanese only), March 31, 2009 ...

*Greenville Swamp Rabbits

The team was renamed to the Swamp Rabbits to strengthen the team's ties to Greenville. The name Swamp Rabbits was a local name ... In 2005 the railroad was abandoned and was converted to the Swamp Rabbit Trail. The first season of the Swamp Rabbits and under ... "Greenville's Swamp Rabbits hockey team sold". The Greenville News. January 3, 2018. "Greenville Swamp Rabbits roster". ... "A New Era: Greenville Swamp Rabbits". Official Website of the Greenville Swamp Rabbits. August 25, 2015. Retrieved August 26, ...

*White Rabbits (sculptors)

... "the White Rabbits." From the ranks of the White Rabbits were to emerge some of the most talented and successful women sculptors ... White Rabbits was the name given to a group of women sculptors who worked with Lorado Taft at the World's Columbian Exposition ... Burnham's reply was that Taft could "hire anyone, even white rabbits, if they can get the work done." Taft, an instructor of ... several of the White Rabbits were to obtain other commissions to produce sculpture at the Exposition. Among these were ...

*Mad as Rabbits

"Mad as Rabbits" "Mad as Rabbits" The music video is an exclusive iTunes video, available to view when the deluxe edition of ... "Mad as Rabbits" is a digital and official second single released from Panic at the Disco's second album, Pretty. Odd.. In the ...

*White Rabbits (band)

"White Rabbits - Billboard". "White Rabbits - Billboard Heatseekers". "White Rabbits - Billboard Independent". "White Rabbits - ... White Rabbits". nthWord. Retrieved 2014-06-30. "QRO Magazine - Concert Reviews » White Rabbits : Live". Qromag.com. 2007-06-04 ... "White Rabbits Daytrotter Sessions" (7/16/2007, Daytrotter) "White Rabbits Daytrotter Sessions" (11/2/2009, Daytrotter) "White ... "Reviews for Fort Nightly by White Rabbits". Metacritic. 2007-05-22. Retrieved 2014-06-30. "White Rabbits: 'Honky-Tonk Calypso ...

*Dirty Little Rabbits discography

Dirty Little Rabbits is the debut album by American indie band Dirty Little Rabbits released on July 6, 2010. "dirty little ... Dirty Little Rabbits released their second EP, Simon, through The End Records. The EP was recorded and produced at the Sound ... Dirty Little Rabbits is an American alternative rock band formed in 2007. The band currently consists of two Extended plays ( ... "Shawn Crahan's Dirty Little Rabbits To Release New EP This Month". Blabbermouth.net. 2009-01-06. Archived from the original on ...

*Dirty Little Rabbits (album)

Dirty Little Rabbits is the only album by American indie band Dirty Little Rabbits released on July 6, 2010. "Hello" was ... "Rabbit Holes" - 4:27 Allmusic review 411mania review Rock Sound review. ...

*Rabbiting

... (also rabbit hunting and cottontail hunting) is the sport of hunting rabbits, often using ferrets or dogs to track ... The rabbit population is endemic in the UK. The use of ferrets (domesticated polecats) in rabbit hunting is common. First the ... Hare coursing Rabbit Hunting: Secrets of a Master Cottontail Hunter, by Dave Fisher (2002) ISBN 0-9707493-6-8 Rabbit Hunting: ... ATVS are also popular vehicles for rabbiting. They provide rapid acceleration making it easy to chase down rabbits. A long net ...

*Rabbits and hares in art

... the Rabbit Boy and Rabbit, by Henry Raeburn 1814 Zan Zig performing with rabbit and roses, magician poster, 1899 White rabbit ... Titania and Bottom with white rabbits Feeding white rabbits, Frederick Morgan, Paris The White Rabbit from Alice in Wonderland ... Netsuke with rabbit Sculptures representing rabbits and hares The Rabbit statue is one of the 12 Chinese zodiac portrayed in ... Rabbits also live underground, an echo of the tomb of Christ. As a symbol of fertility, white rabbits appear on a wing of the ...

*Dutch rabbit

Rabbit Club Dutch Rabbit Pictures The British Rabbit Council UK Dutch Rabbit Club Greater London Dutch Rabbit Club Dutch Rabbit ... Rabbits and hares portal Domestic Rabbit Rabbit http://mom.me/pets/small-pets/19118-popular-pet-rabbit-breeds/item/dutch-rabbit ... However, after dwarf rabbits were developed, the popularity of the Dutch rabbit dwindled. Nevertheless, the Dutch rabbit ... The Dutch Rabbit is in general a calm, easy-going rabbit. They make a good domestic pet, are friendly and are easy to train. ...
Rabbits on the Run è il quarto album della cantautrice statunitense Vanessa Carlton, pubblicato il 26 luglio 2011. Testi e musiche di Vanessa Carlton eccetto dove indicato. Carousel - 3:16 I Dont Want to Be a Bride (Vanessa Carlton, Stephen John Osborne, Ari Ingber) - 4:01 London - 4:19 Fairweather Friend - 3:55 Hear the Bells - 3:44 Dear California (Carlton, Ingber) - 3:19 Tall Tales for Spring - 4:28 Get Good - 3:54 The Marching Line - 3:30 In the End - 2:53 ^ (EN) Stephen Thomas Erlewine, Vanessa Carlton: Rabbits on the Run AllMusic Review, AllMusic. URL consultato il 25 agosto 2017. ^ (EN) Rabbits On the Run, su iTunes. URL consultato il 20 agosto 2017. ^ (EN) Vanessa Carlton - Rabbits on the Run, su All Music. URL consultato il 20 agosto 2017 ...
Abstract: : Purpose: To propose a model of late onset diffuse lamellar keratitis(DLK) that is observed after chemical or mechanical corneal injury in patients with previous laser in situ keratomileusis (LASIK). Methods: Corneal flaps were created in eight eyes from four White New Zealand Rabbits. The flaps were reflected and then repositioned and allowed to heal for two weeks. One eye of each rabbit was then given either a chemical (0.5N NaOH) or mechanical epithelial injury with the contralateral eye serving as control. Corneas were then harvested one day after the injury was created for microscopic analysis. Results: Histopathalogical analysis of sections from corneas that sustained mechanical injury show focal aggregates of heterophils, macrophages, and mild corneal edema at the flap-stromal interface. After chemical injury, in addition to heterophils and macrophages, focal and subepithelial aggregates of fibroblasts and myxomatous stromal changes were observed at the flap-stromal interface. ...
Rabbits on the Run é o quarto álbum de estúdio da cantora e compositora Vanessa Carlton, estava previsto para ser lançado em 21 de junho de 2011, porém teve seu lançamento adiado para 26 de julho, sendo que no Brasil o álbum foi distribuído na segunda quinzena de setembro, pela LAB 344. Para compor as dez canções do novo álbum - produzido por Steve Osborne, e gravado ao vivo no Real World Studios de Peter Gabriel -, Carlton se inspirou nos livros Uma Nova História do Tempo (Stephen Hawking) e Watership Down (Richard Adams). Além de Steve Osborne (U2, B-52s, KT Tunstall), Rabbits on the Run conta com as colaborações de Patrick Hallahan (My Morning Jacket) e Ari Ingber (The Upwelling). "Carousel" (Vanessa Carlton) "I Dont Want to Be a Bride" (Carlton, Ari Ingber, Steve Osbourne) "London" (Carlton) "Fairweather Friend" (Carlton) "Hear the Bells" (Carlton) "Dear California" (Carlton, Ingber) "Tall Tales for Spring" (Carlton) "Get Good" (Carlton) "Marching Line" (Carlton) "In the ...
Tissue factor (TF) is a transmembrane protein that binds factor VII/VIIa, thus activating the extrinsic blood coagulation pathway. Since this pathway appears to be involved in the formation of intravascular thrombi, the anti-rabbit TF monoclonal antibody, AP-1, was produced and tested as an antithrombotic agent in a rabbit model of recurrent intravascular thrombosis. In this model, a plastic constrictor is positioned around the injured rabbit carotid arteries, and flow is monitored with a Doppler flow probe. This produces cyclic flow variation (CFV) in the carotid artery, which is caused by recurrent formation and dislodgment of thrombi at the site of the stenosis. After monitoring CFV pattern for 30 minutes, AP-1 was infused intravenously into nine rabbits at doses of 0.05 to 1.5 mg/kg body weight, and a control monoclonal antibody that does not react with rabbit TF was infused into four additional rabbits. In all rabbits receiving AP-1, CFV was abolished, and a steady normal blood flow was ...
Since the earliest days of the Internet, rabbits and all things rabbit have been flourishing online. A Google search of "rabbit" in mid-2008 led to 114 million hits, with the House Rabbit Societys website, www.rabbit.org, as number one.. Rabbits have, in fact, been a force on the Internet since the earliest public use of the new technology. Rabbit.org for example, was created in 1994, and attracts about 50,000 visitors per day to learn about rabbit care and behavior, and to view the bunny pictures on our Rabbit Randomizer page), which is, oddly, our most popular page. Listserves such as Etherbun, Petbunny, and in the 1990s, newsgroups like alt.pets.rabbits allow rabbit lovers from around the world to chat with each other about rabbit issues, and the Bunderground Railroad, run by RabbitWise in Maryland, is a virtual system of volunteers who transport rabbits across the country to aid rescue groups. Thanks to the immediacy of online communication, life-and-death health information, emergency ...
We studied the effects of hypercholesterolemia on the vascular responses of proximal and distal parts of the rabbit coronary circulation in two consecutive studies. For 12 weeks, New Zealand White rabbits were fed a control diet or a diet with 1% cholesterol dissolved in either 3% coconut oil (study A) or ether (study B). Isolated proximal epicardial and distal intramyocardial coronary arteries from control and hypercholesterolemic rabbits were mounted for isometric tension recording in a double myograph. In study A for hypercholesterolemic rabbits (n = 12), the maximal relaxation and sensitivity to acetylcholine (ACh) were significantly decreased in proximal coronary segments contracted with 30 mmol/l potassium solution compared with segments from control rabbits (n = 13). The only change observed in distal coronary segments was a slight decrease in relaxation in response to low ACh concentrations (10(-8) and 3 x 10(-8) mol/l). However, in study B for proximal coronary and distal coronary ...
Oleh : Nurjaman. Thymus gland is the important organ in immunity, especially in producing lymphocyte T cells. Prostaglandin is an antigenic substance that functions as a mitogen.. The aim of this to determine the influence of Prostaglandin as mitogen on the thymus gland of aged male rabbits and young male rabbits.. Forty male rabbits were divided into two groups, the firs group consists of twenty aged male rabbits and the second group consists of twenty young rabbits . The twenty aged rabbits were divided randomly into two groups (group I = 10 rabbits, group II = 10 rabbits). The twenty young rabbits were divided randomly into two groups (group I = 10 rabbits, group II = 10 rabbits). Before the experiment began, all rabbits were observed for one week for adaptation. After adaptation all rabbits were injected with prostaglandin intra musculary, 1.5 mg for each aged rabbit and 0.75 mg for each young rabbit. One week after injection all rabbits of group I (aged and young rabbits) were killed and ...
Purpose: : Purpose of this study was to examine the efficacy of UV filter in eye drops (Item T1558) on the rabbit cornea irradiated with UVB rays. Methods: : Adult New Zealand white rabbits were employed in our experiments. In the first group of rabbits corneas of both eyes were irradiated with UVB rays (312 nm, a dose per day 1.01 J/cm2), in the second group of animals with UVB rays (312 nm, a dose per day 0.5 J/cm2). In both groups of rabbits the irradiation took place once a day for four days. During the irradiation, the Item T1558 (UV filter) was dropped on the right eye and buffered saline on the left eye. After the end of irradiation (on day four) the animals were left without any treatment for one day and sacrificed (on day five). The central corneal thickness was measured by Pachymeter SP-100 (Tomey Co., Japan) in all rabbits, always before irradiation and also on day five before killing the animals. After the death of animals the corneal centers (a circle of 6 mm diameter) were examined ...
Can this antibody be purchased biotinylated? If so, then you can work with it in the same way as mouse on mouse kits with rabbit serum instead of mouse serum added, not so much fun. However, there was a publication in Lab Vision, a now defunct journal and this method is also in Gus Analytical Morphology book, from Biotechniques for doing rabbit on rabbit IHC. The Xenon technology sounds much easier and readily available. At 12:47 AM 4/28/2006, you wrote: > Dear Narinder, > > Its a wild guess and havent tried it, but perhaps worthwhile to test > (....and better than nothing): > > The LabVision CD3 rabbit monoclonal antibody (clone SP7) reacts very > well with a lot of different species (human, rat, mouse), so to my > opinion there is a good chance it reacts with rabbit CD3 as well. > Just test it on some lymphoid rabbit tissue and look through heavy > background staining (we have a rabbit-on-rabbit situation here and you > will observe a lot of plasmacells and staining near vessels!) whether > ...
Photo about Grey and white rabbit on a white background, close up. Concept - pets, Easter, laboratory animals, testing of drugs, vaccines. Image of mammal, grey, front - 112979541
Фрирайд. Rabbit On The Roof (2014). Сезонный каталог горных лыж 2014. Описание, конструкция, отзывы тестеров. Результаты тестов горных лыж.
Methods Fifty male New Zealand white rabbits were randomly divided into five groups (n = 10 each). The rabbits in the normal group were fed with normal diet, while rabbits in model group and drug treatment groups were fed with high cholesterol, then receiving injury of the left carotid artery adventitia with digestion and blunt dissenction, meanwhile the contralateral ones were treated as sham operation. After establishment of atherosclerotic rabbit model, the rabbits were treated with atorvastatin or different dosage of Banxiao for 16 weeks according to the protocol. At the end, serum lipid and relative gene expressions in different tissues were investigated with FPLC and qPCR. And immunohistochemical analysis of carotid arteries were also evaluated.. ...
So much to learn, so little time! I recently did a guest appearance on Wisconsin Public Radio and didnt do a very good job answering a question about a rabbit who pottied on the couch instead of its litter box. Thanks to an alert listener and member of the Wisconsin House Rabbit Society, Ive learned a lot since. And I have to admit I find it fascinating. You all know Im an animal behavior addict, whether its dogs or donkeys or doodle bugs, and I even had rabbits for a time, so Im gratified to learn more about them.. Im not proud of my own efforts at rabbit husbandry. It was a very, very long time ago, before I knew much at all about animals and animal behavior, and the rabbits lived outside in a cage in a building. Granted, it was warm and safe, but one of the most important things I now know about rabbits is that rabbits are like dogs in that they are highly social and inquisitive. Keeping a rabbit in a cage outside with little social interaction is no life for a rabbit. (Thank heavens we ...
... Supreme Selective 4+ is a tasty, balanced diet for mature rabbits. This natural blend contains fresh timothy hay and thyme to stimulate the appetite and contains other natural ingredients to provide nutritional support for the old...
BioAssay record AID 224020 submitted by ChEMBL: Evaluated for the reduction of cholesterol ester level in thoracic aorta of NZW rabbits with 0.25% cholesterol in diet.
TY - JOUR. T1 - Neutrophil depletion attenuates interleukin-8 production in mild-overstretch ventilated normal rabbit lung. AU - Kotani, Mariko. AU - Kotani, Toru. AU - Ishizaka, Akitoshi. AU - Fujishima, Seitaro. AU - Koh, Hidefumi. AU - Tasaka, Sadatomo. AU - Sawafuji, Makoto. AU - Ikeda, Eiji. AU - Moriyama, Kiyoshi. AU - Kotake, Yoshifumi. AU - Morisaki, Hiroshi. AU - Aikawa, Naoki. AU - Ohashi, Akira. AU - Matsushima, Kouji. AU - Huang, Yuh Chin T. AU - Takeda, Junzo. PY - 2004/2. Y1 - 2004/2. N2 - Objective: Acute lung injury induced by lung overstretch is associated with neutrophil influx, but the pathogenic role of neutrophils in overstretch-induced lung injury remains unclear. Design: To assess the contribution of neutrophils, we compared the effects of noninjurious large tidal volume (VT) ventilation on lungs in normal and neutrophil-depleted animals. Setting: Research animal laboratory. Subjects: Twenty-six male Japanese white rabbits. Interventions: Animals were mechanically ...
The American Rabbit is a breed of rabbit, recognized by the American Rabbit Breeders Association (ARBA) in 1917. By the ARBA standard, American rabbits have a mandolin body shape and a coat ideal for use as fur. It has also been noted for a good sweet temperament and good mothering abilities. As with all domestic rabbits, the American breed is of the species Oryctolagus cuniculus, the European wild rabbit. The American Rabbit was originally accepted into the ARBA as a Blue rabbit, and historically has been characterized as having the deepest, darkest fur of all blue or grey rabbits. The color at its best is "uniform rich, dark slate-blue, free from white hairs, sandy or rust color". A white variety named American White Rabbit was recognized in 1925. It was developed by selecting white sports (mutants), and adding in white red-eyed white (albino) Flemish giants in the bloodline. It is an albino variety of rabbit (otherwise known as red-eyed white) - while blue-eyed whites have appeared, they ...
A highly specific, sensitive (25 pg) radioimmunoassay for prostaglandin A is described; the assay is characterized by high reproducibility (coefficient of variation 1-2%) and low cross-reactivity with respect to PGE1 and PGE2 (10%), PGB2 (15%), and PGF2α (0.01%). High specificity for PGA was obtained by chromatographic separation of the prostaglandins. Since it has been suggested that PGA is a natriuretic "hormone," the concentration of PGA in the renal cortex, outer medulla, and papilla was determined in rabbits on low-sodium and high-sodium diets in the presence and the absence of the prostaglandin synthetase inhibitor indomethacin. In rabbits on the low-sodium diet (12 mEq/24 hours). PGA2 was 15 ± 4 pg/mg in the cortex, 502 ± 67 pg/mg in the outer medulla, and 3740 ± 640 pg/mg in the papilla. In rabbits on saline loading (56 mEq/24 hours), cortical and outer medullary PGA2 rose to 32 ± 6 pg/mg and 1275 ± 290 pg/mg, respectively, but papillary PGA decreased to 1842 ± 480 pg/mg. PGA ...
Spontaneous in vitro T cell rosette formation at room temperature leading to enrichment of B cells has been reported. We tested 10 individual New Zealand White rabbits sequentially, separating the lymphocytes either at room temperature or at 37 degrees C. T cells are lost constantly at room temperature but to a lesser extent at 37 degrees C. The determination of the yield of lymphocytes after Ficoll separation gives the best control for the accuracy of the results. If lymphocytes are separated at 37 degrees C and if the yield of lymphocytes is greater than 45%, the variation in T cells is small and their number is constant between 62 and 74%. These data show that the reported wide range of T cells in rabbit peripheral blood is due to methodological errors and not inherent in the rabbit ...
Rabbits are among the most widely used animals in experimental studies in basic and clinical medical sciences. MR images may also be coupled with the studies of rabbits and may provide important clues to the researchers.. Several coils and parameters may be implemented for experimental MR imaging of the rabbit brain, but because of the small size of this brain, the image quality may not be satisfactory. This letter briefly describes our efforts to improve the quality of MR images of the rabbit brain by using different coils and varying technical parameters.. We retrospectively evaluated the MR imaging of 87 male New Zealand white rabbits used in cranial experimental studies between 1994 and 2003 on a 1T system. Experiments had been conducted in conformity with the Guide for the Care and Use of Laboratory Animals1 and were approved by the local ethics committee. A circularly polarized head coil, a quadrature extremity coil, or a 3-inch (7.62-cm) circular surface coil and fast spin-echo images ...
... are mammals belonging to the family Leporidae. Rabbits are known for their long ears. They have powerful hind legs and a short tail. Rabbits can make wonderful pets. Rabbits are playful, intelligent, curious and can be trained. Rabbits have different personalities and need human interaction. Rabbits have a long life span of 8 to 10 years.
... are mammals belonging to the family Leporidae. Rabbits are known for their long ears. They have powerful hind legs and a short tail. Rabbits can make wonderful pets. Rabbits are playful, intelligent, curious and can be trained. Rabbits have different personalities and need human interaction. Rabbits have a long life span of 8 to 10 years.
Okay, so I lied. Even this almost constant, almost universal truth about rabbits does not apply to every single rabbit under the moon. How can you determine whether your bun is one of these rareties? You must ask other rabbits to tell you. Read the how-to series of articles in the House Rabbit Journal, and set up a few introductions. If you find that Thumper really does not share your interest in living with rabbits, please consider a non-rabbit non-human friend for him. This is especially important for rabbits who are home alone much of the time. The solitude of an empty apartment would be unnatural even for the wild animals whom we label as solitary. As she goes about her daily business, even a solitary animal like an orangutan is surrounded by other living creatures. Dont let a busy schedule give you the guilts about quality time your rabbit is missing. Think guinea pigs. Think cats. Some bunnies coexist contentedly with a feathered friend. Cross-species introductions, in which territorial ...
We evaluated the propagation of myocardial injury in a model of coronary artery occlusion and reperfusion in control and hypercholesterolemic rabbits. This was done by examining the differences in the infarct size and in the extent of leukocyte accumulation resulting from coronary artery occlusion (30 min) followed by reperfusion (2 or 48 hr) in rabbits fed 1% cholesterol for 4 days vs. controls not fed cholesterol. There was no significant difference in the infarct size in the 2-hr (45.7 +/- 6.7%, n = 8) vs. 48-hr (48.8 +/- 5.8%, n = 9) models of reperfusion in control rabbits. However, infarct size in the cholesterol-fed rabbits at 2 hr (64.0 +/- 4.1%, n = 6) or 48 hr (72.3 +/- 3.0%, n = 8) of reperfusion significantly exceeded that in the corresponding controls (P , .05). The infarct in cholesterol-fed rabbits at 2 hr of reperfusion was smaller than that at 48 hr of reperfusion, but not significantly. Treatment with S-nitroso-N-acetylpenicillamine, a nitric oxide donor, effectively reduced ...
After injection in bloodstream, a lipid nanoemulsion (LDE) resembling low-density lipoprotein (LDL) concentrate in atherosclerotic lesions of cholesterol-fed rabbits. Here, rabbits with atherosclerosis were treated with carmustine, an antiproliferative agent used in cancer chemotherapy, associated to LDE to investigate the effects on the lesions. Eighteen male New Zealand rabbits were fed a 1% cholesterol diet for 8 weeks. After 4 weeks nine animals were treated intravenous saline solution and nine with intravenous LDE-carmustine (4 mg/kg, weekly for 4 weeks). LDE-carmustine inhibited atherosclerotic lesions by 90%, compared to controls. LDE-carmustine reduced presence of macrophages, smooth muscle cells, and regulatory T-cells in the arterial intima as well as the expression of matrix metallopeptidase-9, interleukin-1β and TNF-α and lipoprotein receptors (LDL receptor, LDL-related protein-1 and scavenger receptor class B member 1). In conclusion, LDE-carmustine treatment resulted in marked ...
Hearts from 10 New Zealand White male rabbits (mean weight, 3.7±0.4 kg) were isolated, mounted on a vertical Langendorff apparatus, and perfused with a modified Tyrodes solution as described earlier.30 The experimental setup is shown in Fig 1⇓. The temperature of the perfusing solution was maintained at 37±0.5°C and the perfusion pressure at no less than 50 mm Hg. AV node ablation was performed mechanically through a pair of surgical tweezers to control the intrinsic heart rate. Subsequently, the heart was paced at 500-ms cycle length by electrical stimuli of twice diastolic threshold strength and a duration of 2 ms from the right ventricular apex by use of a programmable stimulator and stimulus isolator (Bloom). The heart was immersed in a Tyrodes solution-filled chamber 12 cm wide and 7.5 cm high. A three-lead volume-conducted ECG was obtained by means of four Ag-AgCl electrodes flanking the tissue chamber in an approximate Einthoven configuration.31 32 The signals were amplified by a ...
We characterized cytochrome P-450-dependent arachidonate (P-450-AA) metabolism throughout the intestinal tract, since some metabolites derived via this pathway modify epithelial ion transport and regional blood flow. Microsomes (0.3 mg/ml) were prepared from each region of the intestines of anesthetized New Zealand White male rabbits and incubated with [14C]AA (7 microM) for 30 min at 37 degrees C. In the presence of NADPH (1 mM), ileal microsomes exhibited the greatest P-450-AA metabolism, whereas duodenal microsomes exhibited little or no activity. For jejunal, ileal, and cecal microsomes, AA metabolism was reduced in the absence of NADPH and by boiling microsomes, was unaffected by indomethacin (10 microM) and BW-755C (50 microM), but was significantly attenuated by the P-450 enzyme inhibitors, 7-ethoxyresorufin (1 microM) and SKF-525A (100 microM). However, colonic (ascending, transverse, and descending) microsomal activity was inhibited by both P-450 and lipoxygenase inhibitors. Analysis of ...
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Now that bunny is out, its time to lift him. The following are directions (for right- handed people) if you are uncertain, or having trouble lifting your medium-to-large-sized rabbit.. Start with the rabbit on the floor, say, in the bathroom. Approach him slowly and pet him, leaving your hand on his head to discourage escape. Rabbits feel uneasy, and are most likely to struggle, when they are suspended in the air. So be prepared before you lift. Visualize how you want to hold the rabbit once you have lifted him. For example: the rabbit right side up, nose pointed to the left, left side along your midriff, supported by your right arm. Next, slide the rabbit around while he is still on the ground, until he matches this position, i.e. sideways and pointed left. Is he thinking of leaving? Keep your hand on his head, or gently grasp his shoulders. Do not lift by the scruff. If he runs, dont grab him. Follow him, using babytalk to lighten the moment. Wait until he stops, and start again.. Kneel, and ...
Metabolites of AA from the 15-LO-1 pathway THETA and HEETA are EDHFs and relax rabbit arteries (7, 8, 42). Other metabolites of AA from LO pathways 15-HETE, 12-HETE, and 15(S)-hydroperoxyeicosatetraenoic acid are inactive in the rabbit arteries (10, 25, 31). We have previously shown that ACh or AA relaxations were higher in the arteries from younger rabbits (neonates to 4 wk old) compared with the arteries from their older counterparts (8 or 16 wk old) (3, 37). This difference was independent of the NO or PG effect but was due to lower 15-LO-1 expression and decreased THETA and HEETA synthesis in the endothelium of the arteries from 8- and 16-wk-old rabbits. The 15-LO-1 expression and THETA and HEETA synthesis were induced by IL-13 (38) and hypercholesterolemia (18, 30) in rabbit aortas and by hypoxia in rabbit neonatal pulmonary arteries (47) and HRMVECs (5). An increased expression of endothelial 15-LO-1 is also sufficient to enhance the relaxations to ACh or AA in rabbit arteries (2, 4). ...
Preterm-born children suffer from neurobehavioral disorders. Premature birth terminates the hypoxic in utero environment and supply of maternal hormones. As the production of interneurons continues until the end of pregnancy, we hypothesized that premature birth would disrupt interneuron production and restoration of the hypoxic milieu or estrogen treatment might reverse interneuron generation. To test these hypotheses, we quantified interneuronal progenitors in the medial, lateral, and caudal ganglionic eminences (MGE, LGE, and CGE) of preterm- (E29 at D3 and D7) vs. term-born (E32 at D0 and D4) rabbits at equivalent postconceptional ages. We found that both total and cycling Nkx2.1+, Dlx2+, and Sox2+ cells were more abundant in the MGE of preterm rabbits at D3 compared to term rabbits at D0, but not in D7 preterm relative to D4 term pups. Total Nkx2.1+ progenitors were also more numerous in the LGE of preterm pups at D3 compared to term rabbits at D0. Dlx2+ cells in CGE were comparable between ...
Rabbits are a type of mammal in the order Lagomorph, a group that also includes hares and pikas. Despite popular misconceptions, rabbits are not rodents. There are at least 30 species of rabbits on...
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A number of morphologically distinct, spontaneously occurring lesions are present in the rabbit aorta. Intimal atheromata occur in newborn rabbits, decrease in incidence as the rabbit becomes weaned, and are a rarity in the adult. Intimal mesenchymal thickening is first seen in weanling rabbits and is almost universally present in the adult. Medial sclerotic changes involving exclusively the inner one-half of the media and termed "type A" lesions are present in weanling and adult, but not in newborn rabbits.. Type A lesions have a variable gross appearance, but a fairly uniform microscopic appearance, which shows principally fragmentation and calcification of elastic lamina and accumulation of acid mucopolysaccharides.. "Type B" lesions, medial sclerosis involving exclusively the outer half of the media, usually occur throughout the entire aorta, and only in adult rabbits.. ...
My hand is sore with holding the camera and my eyes are strained from looking so hard. I am terrified not only have I found the rabbit, but it is super sized......I run to neurologist....help....I have a giant rabbit on the wee hill right next to my house what do I do....its going to kill me, a slow cruel death.......I show him my sore hand telling him the rabbit must have bitten me, and my eyes are burning from its laser eye death stare.......my neurologist laughs....he says it is just a tiny brown rabbit on a hill miles from your house, even if it started hopping towards you its too far to ever reach you. It never bit you and although there is a lot of things we dont know about rabbits, we do know they dont have laser eyes.....( well 99.9% sure as we are doctors and can never say 100%). Your hand and eyes are just sore from holding the camera for hours...no giant rabbit, no lazer eyes..go home you are not being threatened or attacked by a killer rabbit ...
My hand is sore with holding the camera and my eyes are strained from looking so hard. I am terrified not only have I found the rabbit, but it is super sized......I run to neurologist....help....I have a giant rabbit on the wee hill right next to my house what do I do....its going to kill me, a slow cruel death.......I show him my sore hand telling him the rabbit must have bitten me, and my eyes are burning from its laser eye death stare.......my neurologist laughs....he says it is just a tiny brown rabbit on a hill miles from your house, even if it started hopping towards you its too far to ever reach you. It never bit you and although there is a lot of things we dont know about rabbits, we do know they dont have laser eyes.....( well 99.9% sure as we are doctors and can never say 100%). Your hand and eyes are just sore from holding the camera for hours...no giant rabbit, no lazer eyes..go home you are not being threatened or attacked by a killer rabbit ...
Please register to see prices including your discount. Registration may take up to 24h. For guest orders the standard discount of your institution will apply and discounts are visible on the order confirmation.. ...
AbeBooks.com: Cats, Dogs & Other Rabbits: The Extraordinary World of Harry Whittier Frees (9781904587248) and a great selection of similar New, Used and Collectible Books available now at great prices.
Experiments were done to determine whether undernutrition with consequent loss of weight or failure to gain weight inhibited the development or promoted the regression of the aortic lesions of experimental cholesterol atherosclerosis in the rabbit. The experiments were conducted in such a way as to determine whether undernourished and adequately nourished rabbits fed the same daily doses of cholesterol would manifest different degrees of atherosclerosis at the end of an experiment.. Different experiments tested the effect of undernutrition in young, growing animals that failed to gain weight normally (Experiments 1 and 2); in young rabbits subjected to marked undernutrition both before and during cholesterol feeding (Experiment 3); in fully grown, mature rabbits that lost weight during undernutrition (Experiment 4); and in rabbits that had completed a period of cholesterol feeding before caloric restriction was begun (Experiment 5).. In every experiment it was observed that, if two groups of ...
A dazzling array of stage and screen talent star in this New York premiere at the Westside Theatre. An utterly original show, White Rabbit Red Rabbit has no director, set or rehearsals. Instead, the plays sole performer is handed the script for the first time as they step onto the stage. Exploring themes of obedience and convention, this unique concept allows the actor and audience to discover the play at the same time, and for the writers voice to be rendered completely differently at every single performance. The piece was created by Iranian playwright Nassim Soleimanpour in 2010, during a time when he was barred from leaving Iran because he had refused to do military service. Unable to travel, he sent the play abroad in his stead, and its since been performed the world over and translated into over a dozen languages. Nassim finally gained a passport in 2012, and actually saw White Rabbit Red Rabbit live for the first time a year later in Brisbane, Australia ...
5.1where T is a period associated with the rabbit cardiac cycle. The magnitude of α represents the ratio of temporally varying inertial forces to viscous forces within the flow. If α , 1, it can be assumed that the flow is quasi-steady i.e. steady-state results will faithfully represent flow patterns at various points in the cardiac cycle. However, if α , 1, the flow may not be entirely quasi-steady. Barakat et al. [20] suggest that the rabbit heart rate is typically 250-300 beats per minute (making reference to the studies of Borkowski et al. [34], Wyatt et al. [35], and also the textbook of Weisbroth et al. [36]). Also, Avolio et al. [13] measured heart rates of 210 beats per minute in anaesthetized rabbits, and 288 beats per minute in unanaesthetized rabbits. Assuming a heart rate of 275 beats per minute (with all other parameter values as detailed above), a Womersley number of α ≈ 8 is obtained. Consequently, flow in the rabbit aorta is unlikely to be entirely quasi-steady.. Having ...
reserved, self-conscious, secretive. The Rabbit is the fourth symbol of the Chinese Zodiac and a sign of hope for the people. Rabbits have great fashion sense. They keep an updated wardrobe and care strongly about home decor. They love to be around friends and family. Rabbits lead comfortable lives and prefer not to take risks. If they did take a risk, they would probably make the right decision. Rabbits are rarely wrong. They avoid conflict and confrontation whenever possible. They also avoid change. If there is a Rabbit in a group, he is usually the peacemaker. Rabbits have difficulty expressing personal feelings without breaking into tears. This makes it difficult for Rabbits to form long-lasting relationships. The Rabbit also has trouble sticking to one project.. ...
TY - JOUR. T1 - Myocardial depression in sepsis. AU - Raffa, James. AU - Trunkey, Donald. PY - 1978. Y1 - 1978. N2 - Myocardial failure is uniformly fatal when associated with post-traumatic sepsis and multisystem failure. Controversy exists as to whether endotoxin has a direct effect on the myocardium. A nonanoxic isolated arterially perfused rabbit interventicular septum was used in this study to evaluate the effects of endotoxin, live E. coli, and endotoxin/septic shock plasma on myocardial function and ultrastructure. Purified E. coli endotoxin and live E. coli bacteria did not have a significant direct effect on rabbit cardiac muscle function or ultrastructure. Perfusion of the rabbit septum with plasma from rabbits exsanguinated following a 2-hour septic or endotoxin shock insult, however, caused significant (p ,0.02) myocardial depression when compared with control septa perfused with normal rabbit plasma. Septa perfused with shock plasma demonstrated ultrastructural alterations of ...
Rabbit In The Vestibule is a music studio album recording by HALF PAST FOUR (Eclectic Prog/Progressive Rock) released in 2008 on cd, lp / vinyl and/or cassette. This page includes Rabbit In The Vestibules : cover picture, songs / tracks list, members/musicians and line-up, different releases details, free MP3 download (stream), buy online links: ebay and amazon, ratings and detailled reviews by our experts, collaborators and members.
Antibodies prepared in a number of species of mammals, when injected into the uterine lumen of the rabbit, penetrate the yolk-sac splanchnopleur and are found in the foetal circulation. The concentrations achieved in the foetal serum vary according to the species of origin of the immune serum. The present work was undertaken further to investigate the mechanism of this selection, and to determine what part might be played by degradation of the injected protein. Normal bovine, and immune rabbit γ-globulins were trace labelled with 131I and injected into the uterine lumen of rabbits 24 days pregnant. It was found that rabbit agglutinin, and rabbit and bovine iodoglobulin, were present in the serum of foetuses thus exposed. The concentrations of both rabbit agglutinin and rabbit iodoglobulin in the foetal circulation, relative to those injected, were lower than is the case when natural antitoxin is used. The relative concentration of rabbit to bovine iodoglobulin in the foetal circulation is not ...
Its kind of a long title, but essentially Im looking for rabbit cells that I can use to grow up my bacteria. The genus/strain Im working on is very uncommon in use and there are almost no antibodies out there in order to do much of my projected research. So I figure... Ill make my own. Since this is something weve done previously in the lab, I should have it done pretty quickly. The problem with the previous polyclonal rabbit antibody that weve made is that theres so much background! Here we grew up the bacteria in Vero cells, isolated them mostly from the Veros (but still had a lot of debris, since the bacteria is really sensitive, so its hard to seperate them from the cell debris still in there without killing them all!) and injected that into the rabbit. As a result, lots and lots of background ...
In anesthetized paralyzed term newborn rabbits at various postgestational ages (from birth up to 16 days), we measured by micropuncture technique the hydraulic pressure of the pulmonary interstitium (Pip), the extrapleural parietal interstitium, and
May is looking to be a very rewarding month for the Rabbit and one where they can accomplish a lot, especially in their work place. The Rabbit can climb new heights in May and really make some progress in all aspects of their life if they put some hard work and a positive attitude in. Have a great month.
THE Rabbitohs wonderboy given first crack at the No. 1 jersey, has played fullback just once before this year - for 30 minutes in a schoolboy game.
The Jaguar XJ, The flagship of the Brand. The idea behind the spot was to demonstrate the performance, power, beauty and agility of Jaguars premiere nameplate.
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Rabbits are the third most popular pet in the UK but still a little mysterious and rather poorly served. As still a wild animal they are programmed as prey species, they react badly to stress and have horribly complex gut physiology.. But nonetheless they are great and popular pets. We recommend anyone wanting to know more about rabbit keeping visit the Rabbit Welfare Association & Fund website (see the link below).. Its not just rabbits though, our products are used in a wide range of pet rodents from degu to jirds! The erodent website linked below gives some good info on these others.. You can also download our NEW rabbit and small mammal leaflet below! This gives information on healthcare for rabbits, disinfection of the hutch, probiotics for rabbits.. ...
Dental Radiographs in Rabbits Left are two radiographs of the skull taken from two different rabbits during dental examination at Milton Keynes Veterinary Group. These radiographs show the long section of the crowns of the teeth embedded in the bones of the skull. This part of the crown is called the reserve crown and is not visible during examination of the mouth. Rabbit 1 (top) does not have any evidence of dental disease. Rabbit 2 (bottom), however, has advanced dental disease. Many teeth are missing or have stopped growing. There are associated long term changes in the skull. These radiographs helped us to rule out dental disease in the rabbit 1, and to decide how to manage the dental disease in the rabbit 2.. ...
Marsh rabbits eat a variety of plants found in and around wetlands. They are most active at night, dusk and dawn, the same time many of the marsh rabbits predators - owls, foxes, bobcats and alligators - are active as well.. Breeding occurs year-round but peaks December through June. On average, a female marsh rabbit produces six or seven litters of two to four young per litter each year. The nests are lined with grass and breast fur and are located on the ground in thickets, stumps or logs. By four weeks of age, the young rabbits are weaned and are foraging for themselves.. ...
John Updikes Rabbit novels (Rabbit, Run; Rabbit Redux; Rabbit Is Rich; Rabbit at Rest) will be adapted for television after the
Baby Amami Rabbits are called kits,kittens,or bunnies.Some sources say the Amami Rabbit only has 1 kit at a time,and other sources say they have 2 to 3,but it is agreed that they generally have 2litters each year.The mother builds a den lined with plant materials and tufts of fur then seals the top with the same material so it looks like the rest of the forest floor. Like other rabbits,the mother leaves her offspring to hunt and only returns every other night in an effort to keep predators from locating her den.She can even feed the kit without completely uncovering the den.She unseals the den when the kit is between 4and 7weeks old and the baby rabbit joins its mother on the evening hunt for food ...
Factor XI (FXI) is an integral component of the intrinsic pathway of the coagulation cascade and plays a critical role in thrombus formation. Because its role in the pathogenesis of cerebral microembolic signals (MES) is unclear, this study used a potent and selective small molecule inhibitor of FXIa, compound 1, to assess the effect of FXI blockade in our recently established preclinical model of cerebral MES induced by FeCl3 injury of the carotid artery in male New Zealand White rabbits. Ascending doses of compound 1 were evaluated simultaneously for both carotid arterial thrombosis by a Doppler flowmeter and MES in the middle cerebral artery by a transcranial Doppler. Plasma drug exposure and pharmacodynamic responses to compound 1 treatment were also assessed. The effective dose for 50% inhibition (ED50) of thrombus formation was 0.003 mg/kg/h compound 1, i.v. for the integrated blood flow, 0.004 mg/kg/h for reduction in thrombus weight, and 0.106 mg/kg/h for prevention of MES. The highest ...
Rabbits make great pets: they are easy to keep; can be litterbox trained like cats; and can live a long, healthy life, providing many hours of enjoyment. The average life span of a domestic rabbit is 6 to 10 years. If kept outdoors, rabbits need to live in a secure location safe from predators. If rabbits are kept indoors, the house must be "bunny proofed" to remove items that rabbits could chew and destroy or that could be harmful, such as electrical cords. Rabbits need to be kept in a clean, climate-controlled environment with fresh water and good nutrition. Pet rabbits typically live longer than rabbits for commercial use, so the goals for feeding pet rabbits differ from those for production rabbits. ...
Before I start, may I stress the point that I am NOT a vet. If your rabbit chokes please consult a vet! It is best to consult your vet on correct techniques, as although I have consulted a vet for this post it is difficult to explain the methods of dislodging. As most of us know, rabbits are greedy animals. It s a general fact of life that all rabbit owners know! Sometimes, a rabbits greed can be its downfall. Sadly, there seems to have been a massive increase of cases where a rabbit has
Before I start, may I stress the point that I am NOT a vet. If your rabbit chokes please consult a vet! It is best to consult your vet on correct techniques, as although I have consulted a vet for this post it is difficult to explain the methods of dislodging. As most of us know, rabbits are greedy animals. It s a general fact of life that all rabbit owners know! Sometimes, a rabbits greed can be its downfall. Sadly, there seems to have been a massive increase of cases where a rabbit has
Your vet will carry out a nose to tail MOT when your rabbit is given its booster vaccinations. You can play a role too by following the guidelines below to keep an eye on your rabbits health and help him to stay in tip top condition and live a long and healthy life:. Look out for changes in your rabbits food consumption, drinking and toilet habits. Does he have less energy or is he slower in getting up or jumping? Monitor your rabbits faeces for colour, consistency and signs of worms. Rub your hands over your rabbits body including his head, legs and feet to check for any lumps or bumps or anything stuck in his pads. Also keep your eyes open for evidence of fleas and other parasites. Check your rabbits coat quality and whether any dandruff or hair loss is evident. Is your rabbit scratching, chewing or biting excessively?. Check your pets nose, eyes and ears for any abnormalities or discharge. Your rabbits nose should be moist, the corners of his eyes should be free of discharge and his ...
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Snuffles is used to describe a variety of symptoms your rabbit may have, such as a snotty nose, runny eyes, sneezing and wheezing. Whatever the symptoms, the conditions is likely to be caused by a bacterial infection. Your vet can give an antibiotic to try to alleviate symptoms. However, sometimes the symptoms will just be masked by the antibiotic and may re-appear at times of stress or if the rabbit is unwell with another illness. If your rabbit has any of these symptoms a prescription of flu-strength carrots wont be enough - you should take it to the vet for a check up! ...
The endothelial permeability of aorta (EPA) is influenced by atherosclerosis. Whether the physiological difference in EPA is a sex-dependent phenomenon remains to be determined. The objective of this study was to determine the EPA difference between male and female rabbits. An experimental model was designed to obtain 4 groups of animals. The ovariectomized rabbits were fed with normal (group I) and 1% cholesterol-rich diets (group III). The male rabbits also received normal (group II) and cholesterol-rich diets (group IV). After 5 wks, the EPA was measured by Evan Blue (EB) dye uptake method. The EB uptake was significantly (p|0.05) lower in females, regardless of the diet they used. In groups I to IV, the mean±SD EB uptake was 4.83±2.06, 15.15±2.91, 7.01±2.40, and 20.58±3.62 mg/g weight of aorta, respectively. The lower EPA in females may play a role in reducing the risk of development of atherosclerosis.
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Penetration of rabbit skin is estimated by a technique closely akin to the one-day cuff method of Draize and associates, using groups of four male albino New Zealand rabbits weighing 2.5 to 3.5 kg. The fur is removed from the entire trunk by clipping, and the dose is retained beneath an impervious plastic film. Dosages greater than 20 mL/kg cannot be retained in contact with the skin. The animals are immobilized during the 24-hour contact period, after which the film is removed and the rabbits are caged for the subsequent 14-day observation period. The LD50 was ,8100 mg/kg bw. ...
I spoke to the owner as she was paying the bills after consultation with Dr Daniel and not accepting amputation as the medical advice. The rabbits leg had swollen at least 3 times and multiple yellow abscesses flowered inside the leg. "Do you know that this rabbits life is endangered as his leg will become gangrenous and septic, spreading bacteria to her whole body and killing her? I have already given you a below cost fee to amputate her twisted leg. Yet you want to try TCM ...
Pet rabbits can be messy, and although most rabbits can be trained to use a litter box, sometimes accidents happen. When your pet rabbits have accidents on their bedding or in their cages, the mess must be cleaned up right away to prevent odors. Vinegar is not only inexpensive, but it is also a natural deodorizer and disinfectant.. ...
How to Care for Disabled Rabbits. If your rabbit is disabled, you will find yourself doing a lot more for your rabbit than either he or you could have imagined. Since rabbits are very independent animals, your rabbits disability will make...
One of the advantages of production in tropical countries is that rabbits can be fed forages and agricultural byproducts not suitable for human consumption. In general, if available feedstuffs are suitable for poultry production, then it is more efficient to produce poultry rather than rabbits. The role that rabbit production can play is in the utilization of fibrous by-products that are useful neither for poultry nor swine, and of forages that may be available in insufficient quantities for ruminants. When these feeds make up the bulk of the diet for rabbits, the use of a small quantity of concentrate feed to improve performance can be justified. The growth performance of rabbits in studies reported from tropical countries is generally in the range of 10 to 20 g per day, in contrast with the 35 to 40 g per day which is commonly observed in temperate regions. The lower result in the former case may be attributed to a number of factors, including heat stress as well as diet. Only limited data are ...
Ny chickens and other animals live in the country while me and my rabbit live in the city. There are tons of rabbits in the area.Lots of...
One of the first things you should remember is that you should never, ever bathe your bunny rabbit! While you can use a clean, damp cloth soaked in lukewarm water to wipe your rabbit (their skin and hair) you should never place a rabbit in a bath. They are not comfortable having baths, so do not try to submerge them in a bathtub or sink.. Its okay to have a very shallow, open "pan" with barely enough water to cover the feet (never past the bottom of the tail) to help get your rabbits feet and/or bottom clean. And if you feel like you need some soap, make sure it is mild, hypoallergenic, gentle soap and even then only use the tiniest amount on your lukewarm, damp cloth and make sure to "rinse" every bit of it off. It is also imperative that your rabbit be dried thoroughly.. Beware that rabbits tend to be so uncomfortable with the idea of a bath in water that their fear can cause serious harm (as in shock and death).. Try a Dry Bath ...
Normal Rabbit Serum, 5 ml. Serum is the clear, straw-colored, liquid portion of blood plasma that does not contain fibrinogen or blood cells and remains fluid after clotting.
Derm McG is raising funds for Bunsen Bunnies - A webcomic about Mad Science and Rabbits on Kickstarter! Kickstarter to put BUNNIES on T-shirts. CUTE but DERANGED bunny rabbits meet high QUALITY upper body wear, cuddly AWESOMENESS happens.
How to Raise Rabbits for Food. Domestic rabbits are highly valued for their low fat, low cholesterol, and high quality proteins. They are entirely white meat. Rabbit compares very favorably to chicken, turkey, and some fish for its...
This is your visual warning sign that today is the end of the first month of your new year and dont forget tomorrow morning to say "rabbit rabbit.". The most common modern version states that a person should say "rabbit, rabbit, white rabbit" upon waking on the first day of each new month, and on doing so youll receive good luck for the remainder of that month - hey cant hurt.. ...
According to the Wisconsin House Rabbit Society, rabbits live an average of eight to 12 years. Since rabbits are soft, cuddly, and social, they are popular house pets. If you own a rabbit, you will most likely take it out of its cage for a certain amount of time each day to play.
Rabbits are a popular choice for a pet, living either outdoors in a hutch or in the house as a house rabbit. Regardless of where you choose to house your rabbit, there are a few basic tips to learn to give your rabbit a fun and healthy life. Read more ...
Theodore, a 1-to-2-year-old Dutch rabbit, was dumped at All About Rabbits Rescue. Perhaps he had been an Easter gift, and the reality of taking care of a
A pregnant rabbit gives subtle clues to her pregnancy. Learn these five clues so you will be well prepared for your rabbits impending rabbit litter
Rabbit farming requires modest investment as it needs only simple facilities and small land area. A small rabbit farm could have 15 to 100 rabbits requiring between $5,000 and $10,000 in startup capital. For a meat producing rabbitry selling premium priced rabbit meat, an ROI of 45% during the first year of operation is possible. To start your rabbit farm, prepare a rabbit hutch that is well lit and well ventilated with heating and cooling systems. Metal cages are usually recommended for its ease of cleaning. Equip the cages with feed hopper, watering system, and nest box ...
Zyagen : Rabbit Tissue Sections - Antibodies Kits, Reagents & Biochemical Tissue Sections RNA Products cDNA Products Genomic DNA Products Tissue Lysates Products Premade Northern Blots Premade Western Blots Recombinant Proteins & Peptides Tissue Microarrays
Zyagen : Rabbit Tissue Western Blot - Antibodies Kits, Reagents & Biochemical Tissue Sections RNA Products cDNA Products Genomic DNA Products Tissue Lysates Products Premade Northern Blots Premade Western Blots Recombinant Proteins & Peptides Tissue Microarrays
Albino rabbits are typically bright white in color and have red eyes. Other than those differences, they are identical to any other...
Maybe also something in the exhaust line. Check for a clear tailpipe.. Brad Forrest L King wrote: ,First, thank you for all of your replies, both on and off list. I tried ,it all!! :) , ,Ok, here is the update: , ,Airfilter is clean, even tried a run without the airfilter!! ,Injectors are new ,Fuel Filter is NEW. , ,I tried running the rabbit on a bottle of diesel from under the hood. ,the problem persisted. and Damn, these things really pump some diesel ,through that pump - thank god we have return lines!!! I could empty a ,12 oz bottle in about 1 minute 15 seconds!! , ,I also checked the valve train timing - the cam, injector pump, and crank ,are all in time. unfortunaetly I decided to check this after i did my ,bottle runs - those little valve cover bolts are freaking HOT when you ,are trying to remove them. Got it all buttoned up. , ,I am now going to try and check the injector pump timing - even though I ,dont see any signs that the pump has moved a BIT. I have the adapter ,and an SAE ...
Versele-Laga Complete Cuni Junior Rabbit Food is a protein rich rabbit food for young rabbits up to 6-8 months old. Buy online from Millbry Hill.
set of easter rabbits on white background for design. Download a Free Preview or High Quality Adobe Illustrator Ai, EPS, PDF and High Resolution JPEG versions. ID #734701.
Purina® Rabbit Chow® Show Wholesome AdvantEdge™ is a balanced diet specially formulated to promote proper development, vibrant fur, reproduction. Find more nutrition information here.
Gentaur molecular products has all kinds of products like :search , BBridge \ anti_ PCNA antibody, rabbit serum anti_ PCNA antibody, rabbit serum \ 70-080 for more molecular products just contact us
the white rabbit picture created by hacku022 using the free Blingee photo editor for animation. Design the white rabbit pics for ecards, add the white rabbit art to profiles and wall posts, customize photos for scrapbooking and more.
Anti-phospho-Histone H3 (Ser10) Antibody, clone 63-1C-8, is a recombinant rabbit monoclonal antibody that detects Histone H3 phosphorylated at serine 10. This purified recombinant mAb, also known as Anti-H3S10p, is published and validated in WB, Flow Cytometry, and is specificity verified by DB. Find MSDS or SDS, a COA, data sheets and more information.
... LM Animal Farms Bonanza Gourmet Diet for Rabbits is formulated with the optimal levels of protein, fat and fiber to meet the needs of pet rabbits. Ingredients have been carefully selected based on your pets tastes a...
Purina offers rabbit feeds for pet rabbits, show rabbits, specialty diet rabbits and commercial rabbits, made with the highest quality ingredients.
Housing. Rabbits may be housed indoors or outdoors, but prolonged exposure to temperatures above 80°F (26°C) can cause illness, including heat prostration. Domesticated rabbits should not be kept in temperatures below 50°F (15°C). Rabbits that are kept outdoors in temperature extremes must have a shelter that is heated in winter and cooled in summer.. Your rabbit will appreciate as large a cage as you can provide. The cage should be tall enough to allow your rabbit to stand up on his or her hind legs and long enough to allow your rabbit to hop at least three and a half times, but an even larger cage is better. The cage should allow room for a food dish, a water bottle, a large litterbox, and toys. It should have a nonslip floor. Straw or shredded paper covered with straw or hay can be used as bedding. Your rabbit also needs a soft blanket or pad on which to sleep. The cage and its contents should be periodically sanitized with a disinfectant such as household chlorine bleach diluted to 1 ...
Our rabbit care article library provides information around basic rabbit needs, housing and how to care for domestic rabbits. Also, learn some rabbit care myths.
A) Diagram of a segment of aortic wall showing the regions in which tracer concentrations were measured. The intimal surface of the aortic wall is represented en face, with one intercostal branch ostium in the center. Mean aortic flow (heavy arrow) is from top to bottom. Serial longitudinal sections 2 μm thick were cut through the wall, perpendicular to the luminal surface, starting with a section along the midline (CC′ ). A notch scored on the surface of the block permitted correct alignment of sections in the longitudinal direction. Sections were cut until approximately 80 or 345 μm past the edge of the ostium (light arrows) to create narrow field and wide field maps, respectively. Bar=500 μm (B) Sections along the lines CC′ and DD′ are shown in diagrammatic form (the real section along DD′ is shown in Fig 3); in upstream and downstream regions of each section, the wall was divided into 6 strips, indicated by dotted lines in section CC′ ; tracer concentrations were averaged in the ...
TY - JOUR. T1 - Induction of phosphatidylinositol 3-kinase and serine-threonine kinase-like immunoreactivity in rabbit spinal cord after transient ischemia. AU - Sakurai, Masahiro. AU - Hayashi, Takeshi. AU - Abe, Koji. AU - Itoyuama, Yasuto. AU - Tabayashi, Koichi. PY - 2001/4/13. Y1 - 2001/4/13. N2 - The mechanism of spinal cord injury has been thought to be related with tissue ischemia, and spinal motor neuron cells are suggested to be vulnerable to ischemia. To evaluate the mechanism of such vulnerability of motor neurons, we attempted to make a reproducible model of rabbit spinal cord ischemia. Using this model, the inductions of phosphatidylinositol 3-kinase (PI3-k) and serine-threonine kinase (Akt) were investigated with immunohistochemical analyses for up to 7 days of the reperfusion following 15 min of ischemia in rabbit spinal cord. It has been demonstrated that both PI3-k and its downstream effector, Akt mediate growth factor-induced neuronal survival. Spinal cord sections from ...
Rabbit haemorrhagic disease (RHD), also known as rabbit calicivirus disease (RCD) or viral haemorrhagic disease (VHD), is a highly infectious and often fatal disease that affects wild and domestic rabbits of the species Oryctolagus cuniculus. The infectious agent responsible for the disease is rabbit haemorrhagic disease virus (RHDV), or rabbit calicivirus (RCV), genus Lagovirus of the family Caliciviridae. The virus infects only rabbits, and has been used in some countries to control rabbit populations. RHD first appeared in the Winter of 1983 in Jiangsu Province of the Peoples Republic of China. It was first isolated and characterized by S.J. Liu et al. in 1984. The Chinese outbreak was spread by the angora rabbit, which had originated in Europe. Fourteen million domesticated rabbits died within nine months in the outbreak. In 1984 the virus that caused the disease was identified. The virus spread westward and reached Europe in 1988. The virus has since appeared in Mexico, Cuba, Australia, ...
During the past 50 years two readily distinguishable rabbit-specific diseases caused by Myxoma virus (MYXV) and Rabbit haemorrhagic disease virus (RHDV) respectively, have decimated wild rabbit populations worldwide. Combined with the use of these viruses as biocontrol agents, the consequences for farming, commercial rabbit breeding and rare habitat conservation dependent on rabbit grazing, have been both positive and negative. Moreover, rare predators that rely on rabbits as a food resource, and even hunters, have suffered the consequences of rabbit populations being affected by one or other of these viruses. Rabbit haemorrhagic disease virus was first identified after thousands of domestic rabbits died suddenly in China in 1984. Similar epidemics subsequently occurred in other regions of Asia, the Middle East, Europe and North America, suggesting that the virus had dispersed widely following its emergence in China. However, the discovery that RHDV had circulated apparently harmlessly for many ...
A method developed to study the effect of increased hydrostatic pressure on the isometric tension of a single muscle fibre is described and experiments done at room temperature (18-22°C) on glycerinated rabbit psoas muscle fibres are presented. Increase of pressure (range 1-10 MPa) caused little change in tension transducer response when a muscle fibre was relaxed. However, there was a reversible depression of isometric tension with an increase of pressure when a fibre was maximally calcium-activated or in rigor; the depression was around 15% for active tension and 30% for rigor tension, for an increase of pressure of 10 MPa (ca. 100 atm). ...
Rabbit haemorrhagic disease virus (RHDV) is a calicivirus that infects and frequently kills rabbits. Previously, we showed that the RHDV RNA-dependent RNA polymerase (RdRp) is associated with distinct, but yet uncharacterised subcellular structures and is capable of inducing a redistribution of Golgi membranes. In this study, we identified a partially hidden hydrophobic motif that determines the subcellular localisation of recombinant RHDV RdRp in transfected cells. This novel motif, 189LLWGCDVGVAVCAAAVFHNICY210, is located within the F homomorph, between the conserved F3 and A motifs of the core RdRp domain. Amino acid substitutions that decrease the hydrophobicity of this motif reduced the ability of the protein to accumulate in multiple subcellular foci and to induce a rearrangement of the Golgi network. Furthermore, preliminary molecular dynamics simulations suggest that the RHDV RdRp could align with the negatively charged surfaces of biological membranes and undergo a conformational change
Cholesteryl ester transfer protein (CETP) is a major determinant of plasma levels of high-density lipoprotein-cholesterol (HDL-C) in humans. The anti-atherogenic effect of lowering CETP levels is dependent not only on HDL-C levels but also on a metabolic background of increased low-density lipoprotein or very-low-density lipoprotein. Here we investigated the effects of JTT-705, a chemical inhibitor of CETP, on the development of atherosclerosis in Japanese white rabbits fed on a high cholesterol diet. After 4 weeks on a diet of 0.25% cholesterol-containing chow, 100mg/kg (low dose) or 300mg/kg (high dose) JTT-705 was given, and the animals were monitored at weeks 0, 4, 8 and 12. Aortic atherosclerotic lesions were determined at the end of this period. JTT-705 induced a significant increase in HDL-C in the high-dose group [from 21±3 to 50±7mg/dl (mean±S.E.M.); P,0.0001] compared with the control group (from 21±2 to 27±2mg/dl). The atheromatous area was 60±9% in the high-dose group and ...
Virus-like particles (VLPs), comprised of viral structural proteins devoid of genetic material, are tunable nanoparticles that can be chemically or genetically engineered, to be used as platforms for multimeric display of foreign antigens. Here, we report the engineering of chimeric VLPs, derived from rabbit hemorrhagic disease virus (RHDV) for presentation of foreign B-cell antigens to the immune system. The RHDV capsid comprises 180 copies of a single capsid subunit (VP60). To evaluate the ability of chimeric RHDV VLPs to elicit protective humoral responses against foreign antigens, we tested two B-cell epitopes: a novel neutralizing B-cell epitope, derived from feline calicivirus capsid protein, and a well characterized B-cell epitope from the extracellular domain of influenza A virus M2 protein (M2e). We generated sets of chimeric RHDV VLPs by insertion of the foreign B-cell epitopes at three different locations within VP60 protein (which involved different levels of surface accessibility) ...
Latency-associated transcript (LAT) significantly enhances the spontaneous reactivation phenotype of herpes simplex virus type 1 (HSV-1). The mechanism by which LAT accomplishes this has been elusive. To determine if LATs antiapoptosis activity is involved, the authors used a rabbit eye model to analyze the spontaneous reactivation phenotype of an HSV-1 mutant in which LAT was replaced by an unrelated antiapoptosis gene. This virus, dLAT-cpIAP, contains the open reading frame of the baculovirus inhibitor of apoptosis protein gene (cpIAP) in place of LAT, under control of the LAT promoter. The authors report here that in a rabbit ocular model of infection, dLAT-cpIAP had a spontaneous reactivation phenotype similar to wild-type virus and significantly higher than LAT(-) viruses. This was consistent with their previous findings using the mouse trigeminal ganglia explant-induced reactivation model. Whether LAT (and in the case of dLAT-cpIAP, cpIAP) enhances the spontaneous reactivation phenotype ...
1. The effects of nafazotrom, nordihydroguaiaretic acid (NDGA) and quercetin on Ca2+-induced vasoconstriction were studied in isolated rabbit ear arteries. 2. The arteries were perfused with Ca2+-free and high K+ (75 mM) Krebs bicarbonate buffer. Constriction of the artery was induced by addition of Ca2+ (1.5 mM) to the perfusion fluid. 3. Indomethacin (1 μM) did not alter the response to Ca2+. 4. Nafazatrom (2 or 5 μM) produced a concentration-dependent inhibition of the constrictor response to Ca2+ ranging from 4 to 23% after 1 hr of perfusion and 26 to 62% after 3 hr. 5. Similar effects were obtained with NDGA and quercetin (0.5 and 1 μM). 6. The inhibitory effects of nafazatrom and quercetin were antagonized by Ca2+ (2.5 mM) or Bay K 8644 (1 μM), a calcium channel activator. 7. Ca2+-induced contractions recovered within 30 min after discontinuation of perfusion with quercetin, where nafazatrom and NDGA had longer durations of action. 8. These results suggest that inhibitors of ...

How to Cook a Cottontail Rabbit | Livestrong.comHow to Cook a Cottontail Rabbit | Livestrong.com

Cottontail rabbit meat is nutritious, containing less fat than chicken, turkey, beef, pork or lamb. Use moist-cooking methods ... Cottontail rabbits live wild throughout most of the U.S. and are a favorite prey of small game hunters. ... for tender, flavorful meat because rabbit meat has naturally low moisture content. ... Cut the rabbit into serving pieces. One adult rabbit should yield 2 to 2 1/2 lbs. of bone-in meat, or about four servings. Dust ...
more infohttps://www.livestrong.com/article/447638-how-to-cook-a-cottontail-rabbit/

Novel Calicivirus Identified in Rabbits, Michigan, USA - Volume 15, Number 12-December 2009 - Emerging Infectious Disease...Novel Calicivirus Identified in Rabbits, Michigan, USA - Volume 15, Number 12-December 2009 - Emerging Infectious Disease...

... rabbit hemorrhagic disease virus (RHDV). The novel virus has been designated Michigan rabbit calicivirus (MRCV). Caliciviruses ... Experimentally infected rabbits lacked clinical disease, but MRCV was detected in tissues by PCR. We propose that MRCV ... of the Lagovirus genus other than RHDV have not been described in US rabbit populations. The case-fatality rate was 32.5% (65/ ... We report a disease outbreak in a Michigan rabbitry of a rabbit calicivirus distinct from the foreign animal disease agent, ...
more infohttps://wwwnc.cdc.gov/eid/article/15/12/09-0839_article

Serological response against myxoma virus and rabbit hemorrhagic disease virus in European wild rabbits using commercial...Serological response against myxoma virus and rabbit hemorrhagic disease virus in European wild rabbits using commercial...

T Tung, D Phalen, J-ALML Toribio, Adverse reactions in a population of Sydney pet rabbits vaccinated against rabbit calicivirus ... Serological response against myxoma virus and rabbit hemorrhagic disease virus in European wild rabbits using commercial ... Vaccination may be a useful management tool to control both viral diseases in field conditions, particularly in wild rabbits ... We carried out an experimental study to determine the serological response against myxoma virus (MV) and rabbit hemorrhagic ...
more infohttp://onlinelibrary.wiley.com/doi/10.1002/jwmg.207/abstract?globalMessage=0

Nuttalls Cottontail RabbitNuttall's Cottontail Rabbit

Nuttalls cottontail rabbits are a medium sized rabbit. They grow to be between 35-39cm (13.8-15.4inches) in length and weigh ... the eastern cottontail rabbit and the mountain cottontail, also known as Nuttalls cottontail rabbit. ... There are five species of rabbit and hare in Canada: the Arctic hare, which is the biggest species, the white tail jackrabbit ...
more infohttp://www.northwestwildlife.com/learn/species-reports/nuttalls-cottontail-rabbit/

Unravelling the paradox of rabbit haemorrhagic disease virus emergence, using phylogenetic analysis; possible implications for...Unravelling the paradox of rabbit haemorrhagic disease virus emergence, using phylogenetic analysis; possible implications for...

Rabbit haemorrhagic disease virus was first identified after thousands of domestic rabbits died suddenly in China in 1984. ... Moreover, rare predators that rely on rabbits as a food resource, and even hunters, have suffered the consequences of rabbit ... During the past 50 years two readily distinguishable rabbit-specific diseases caused by Myxoma virus (MYXV) and Rabbit ... commercial rabbit breeding and rare habitat conservation dependent on rabbit grazing, have been both positive and negative. ...
more infohttp://nora.nerc.ac.uk/id/eprint/2841/

Rabbit Gamma Globulin Isotype Control, Invitrogen™ 10mg; Unlabeled Rabbit Gamma Globulin Isotype Control, Invitrogen™Rabbit Gamma Globulin Isotype Control, Invitrogen™ 10mg; Unlabeled Rabbit Gamma Globulin Isotype Control, Invitrogen™

Unlabeled Rabbit Gamma Globulin Isotype Control, Invitrogen™ Gamma Globulins ... Rabbit Gamma Globulin Isotype Control, Invitrogen™ Rabbit Gamma Globulin Isotype Control, 31887, from Invitrogen™., 31887, from ... Host Species: Rabbit. Isotype: Ig Mix. Formulation: 10mg purified isotype control antibody (11.2mg/mL) in PBS and no ... Rabbit Gamma Globulin Isotype Control, Invitrogen™ 10mg; ...
more infohttps://www.fishersci.co.uk/shop/products/thermo-scientific-pierce-affinity-purified-gamma-globulins/11819230

Svendborg Rabbits - WikipediaSvendborg Rabbits - Wikipedia

Svendborg Rabbits is a Danish professional basketball team, from Svendborg. The home ground is The Rabbits House (Kaninhulen ...
more infohttps://en.wikipedia.org/wiki/Svendborg_Rabbits

Battle Rabbits - WikipediaBattle Rabbits - Wikipedia

"Battle Rabbits". Seven Seas Entertainment. Retrieved 10 November 2015. バトラビッツ 02 (IDコミックス ZERO-SUMコミックス) [Battle Rabbits 02 (ID ... Anime and manga portal Battle Rabbits at Seven Seas Entertainment Battle Rabbits (manga) at Anime News Networks encyclopedia. ... Battle Rabbits (バトラビッツ, Bato Rabittsu) is a Japanese manga series written by Yuki Amemiya and Yukino Ichihara. The series is ... バトラビッツ 1巻 (IDコミックス ZERO-SUMコミックス) [Battle Rabbits Volume 1 (ID Comics ZERO-SUM Comics)]. Amazon.co.jp (in Japanese). Retrieved ...
more infohttps://en.wikipedia.org/wiki/Battle_Rabbits

rabbits | Salon.comrabbits | Salon.com

Danish radio station calls out meat eaters "double standards" by killing a baby rabbit on air Lindsay Abrams. ...
more infohttps://www.salon.com/topic/rabbits

Rabbit exchange! : RabbitsRabbit exchange! : Rabbits

... r/rabbits is an open community where users can learn, share cute pictures, or ask questions about rabbits. All fluffy bunny ... lovers are welcome! Please note we are a *house rabbit* subreddit. ... r/rabbits is an open community where users can learn, share cute pictures, or ask questions about rabbits. All fluffy bunny ...
more infohttps://www.reddit.com/r/Rabbits/comments/2mas0d/rabbit_exchange/

Conditioning Rabbits for ShowConditioning Rabbits for Show

If a rabbit wont drink, it wont eat, and finishing a rabbit that wont is impossible. You can hold coats on rabbits that are ... Conditioning Rabbits for Show. Conditioning is very important in a rabbit. If your rabbit is out of condition, it will not ... The rabbit is made in the nestbox. Place the rabbits you select in separate cages. Handle them and take note of how they ... Rabbits that do not get their finishing coat by 5 1/2 months should be culled, as should rabbits with coarse fur and any other ...
more infohttp://www.angelfire.com/ny2/crescentvalley/showconditioning.html

Category:Rabbits - Wikimedia CommonsCategory:Rabbits - Wikimedia Commons

English: Rabbits are small mammals in the family Leporidae of the order Lagomorpha, found in several parts of the world. ... Media in category "Rabbits". The following 8 files are in this category, out of 8 total. ... rabbit (en); Counél (frp); 兔 (lzh); کەروێشک (ckb); أرنب (aeb-arab); أرنب (ar); Aperearusu (gn); thỏ (vi); ယုန် (my); 兔 (yue); ... bunny rabbit, coney, bunnies (en); الأرانب, الأرنب, الارانب, ارنب, التصنيف العلمى للارانب, 🐇, 🐰 (ar); ิbunny (th) ...
more infohttps://commons.wikimedia.org/wiki/Category:Rabbits

Bun Secret Santa! : RabbitsBun Secret Santa! : Rabbits

... r/rabbits is an open community where users can learn, share cute pictures, or ask questions about rabbits. All fluffy bunny ... lovers are welcome! Please note we are a *house rabbit* subreddit. ... r/rabbits is an open community where users can learn, share cute pictures, or ask questions about rabbits. All fluffy bunny ...
more infohttps://www.reddit.com/r/Rabbits/comments/2m2tfz/bun_secret_santa/

rabbits - Good Housekeepingrabbits - Good Housekeeping

Man Saves Rabbit From California Wildfire. The video of the rescue is incredible. By Megan Friedman ...
more infohttp://www.goodhousekeeping.com/content/rabbits/

Category:chl:Rabbits - WiktionaryCategory:chl:Rabbits - Wiktionary

Pages in category "chl:Rabbits". The following 2 pages are in this category, out of 2 total. ... Retrieved from "https://en.wiktionary.org/w/index.php?title=Category:chl:Rabbits&oldid=17392666" ...
more infohttps://en.wiktionary.org/wiki/Category:chl:Rabbits

Clipart - Rabbits - MoonClipart - Rabbits - Moon

And in this awesome old illustration we see rabbits looking at the rabbit on the moon, wowsers! ... there are stories of a rabbit on the moon grinding rice. ... And in this awesome old illustration we see rabbits looking at ... Asia , folklore , Japan , moon_rabbit , rabbits , Space Pictures , telescope , 月㠮兎. Viewed by. 2070 People. Loved by. 1 ... Rabbits - Moon. By. j4p4n. Created. 2013-05-20. Description. In Japan (and all over East Asia actually) there are stories of a ...
more infohttps://openclipart.org/detail/178365/rabbits-moon

Killer RabbitsKiller Rabbits

He assumed his dog was killing the snakes until he saw two rabbits killing another snake! ... The rabbits are apparently protecting two baby bunnies. Del Manso is glad to have the rabbits around, as he raises chickens and ... He said the rabbits lived under a pile of wood in the backyard and were around the same size as a household cat.. "These are ... all joking aside- rabbits can be scary when they want to be. if youve ever heard one scream, youll know what im talking ...
more infohttp://www.neatorama.com/2009/09/24/killer-rabbits/

Three Rabbits PosterThree Rabbits Poster

Find great quality Three Rabbits Posters & Prints in all sizes. 1000s of designs & options available, or custom create your own ... Three Rabbits Poster. Add to Favorites Add to List Add to List ... Three beautiful rabbits with black markings cuddle together in ...
more infohttp://www.cafepress.com/+three_rabbits_poster,576349275

Rabbits - WikiquoteRabbits - Wikiquote

King Arthur: What? Behind the rabbit?. Tim: It is the rabbit!. King Arthur: You silly sod!. Tim: What?. King Arthur: You got us ... including the European rabbit (Oryctolagus cuniculus), cottontail rabbits (genus Sylvilagus; 13 species), and the Amami rabbit ... A bear and a rabbit were taking a shit in the woods. The bear turns to the rabbit and says, "Excuse me, do you have problems ... Bunny is a colloquial name for a rabbit. Quotes[edit]. *Donnie Darko: Why do you wear that stupid bunny suit?. Frank: Why are ...
more infohttps://en.wikiquote.org/wiki/Rabbit

Rabbits Foot FernRabbits Foot Fern

Source URL: https://www.aspca.org/pet-care/animal-poison-control/toxic-and-non-toxic-plants/rabbits-foot-fern ...
more infohttps://www.aspca.org/print/pet-care/animal-poison-control/toxic-and-non-toxic-plants/rabbits-foot-fern

Fat Rabbits on SpotifyFat Rabbits on Spotify

Fat Rabbits on turkulais-helsinkiläinen genrerajavapaa rockyhtye, jonka musiikissa punk ja boogie lyövät kättä hevin ja nu- ... Fat Rabbits, Category: Artist, Albums: Moottoripojat, 1: Maailma on uni, Singles: Sä Et Tiedä Mitä Rakkaus On, Osin Mies, Osin ... Listen to Fat Rabbits now.. Listen to Fat Rabbits in full in the Spotify app ... Fat Rabbits on turkulais-helsinkiläinen genrerajavapaa rockyhtye, jonka musiikissa punk ja boogie lyövät kättä hevin ja nu- ...
more infohttps://open.spotify.com/artist/1zhVm0jLKMNuind9f0KF6N?si=tefBts_MSHeD_fbBrCj7IQ&fbclid=IwAR2zAE86wNLlNftEVnMloqeYK9-c8uhBjMZ0q1pSrjzgrOpK1KcLLvDrkdo

Sick RabbitsSick Rabbits

Rabbits can get by not takeing good care of them and by them not eating is a huge biggie and when your sick rabbits can get ... Rabbits Forum. by The Info-Bunnie 3 months ago. Today, domesticated rabbits are kept as companion animals. My name is Kate ... Has my rabbit got a behavioural problem?My rabbit enjoys going out in the garden and she can be quite nosey if i am doing ... how to prevent foxes from eating your rabbit?are there any ways to stop foxes from eating my rabbit if i leave it in the garden ...
more infohttps://hubpages.com/animals/forum/27571/sick-rabbits

Convention Sales 2013 - Casablanca RabbitsConvention Sales 2013 - Casablanca Rabbits

Transport fee for animals not entered is $25. Any animals not entered in the show will need to be picked up when we arrive at convention on Saturday. ...
more infohttp://www.freewebs.com/whitedkp/conventionshowsale2013.htm

Rabbits/RHS GardeningRabbits/RHS Gardening

Rabbits graze a wide range of plants and can cause sufficient damage to kill young trees, shrubs and herbaceous plants. ... Rabbits. Back to all plant problems. Rabbits graze a wide range of plants and can cause sufficient damage to kill young trees, ... What are rabbits?. Rabbits can cause considerable damage in the garden. They feed on a very wide range of ornamental plants, ... Rabbits usually enter gardens from adjoining common land, farms or woods. Where this is the case, the erection of rabbit-proof ...
more infohttps://www.rhs.org.uk/Advice/Profile?PID=219

Rabbit ShowRabbit Show

3.50 per rabbit/per show for pre-entry. There will be no day of show entries. There will be no fee or penalty for day of show ... No rabbit or cavy is officially entered until required fees are paid, which must be done prior to the start of the show. ... All rabbits and cavies are entered and shown at the risk of the owners and/or exhibitors, and while show sponsors are expected ... As per A.R.B.A. show regulations each rabbit shall have a permanent identifying ear mark (tattoo) in the left ear. There will ...
more infohttps://sites.google.com/view/millbrookfairca/home/rabbit-show
  • RCV and EBHSV have not been reported and lagoviruses other than RHDV have not been described in US rabbit populations, although a low pathogenicity rabbit Vesivirus recently was identified in domestic rabbits from Oregon ( 8 ). (cdc.gov)
  • RHDV affects only rabbits of the Oryctolagus genus which, in the United States, is limited to domestic rabbit species. (cdc.gov)
  • In addition to the highly pathogenic RHDV, the Lagovirus genus includes several distinct but related viruses affecting rabbits or hares. (cdc.gov)
  • In the United States 4 outbreaks of RHD have occurred in domestic, captive rabbits ( O. cuniculi ) since 2000. (cdc.gov)
  • Caliciviruses of the Lagovirus genus other than RHDV have not been described in US rabbit populations. (cdc.gov)
  • Seroprevalence surveys of RHDV or related caliciviruses in US domestic rabbit populations have not, to our knowledge, been published. (cdc.gov)
  • Experimentally infected rabbits lacked clinical disease, but MRCV was detected in tissues by PCR. (cdc.gov)
  • Wild rabbit species in the United States are not experimentally susceptible ( 9 ). (cdc.gov)
  • Rabbit meat can replace chicken in any chicken recipe, including recipes for cold cooked chicken. (livestrong.com)
  • In the United States, it is considered a foreign animal disease, and outbreaks are of considerable economic concern to the US rabbit industry. (cdc.gov)
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