Lacrimal Apparatus: The tear-forming and tear-conducting system which includes the lacrimal glands, eyelid margins, conjunctival sac, and the tear drainage system.Dacryocystitis: Inflammation of the lacrimal sac. (Dorland, 27th ed)Acinar Cells: Cells lining the saclike dilatations known as acini of various glands or the lungs.Tears: The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Exocrine Glands: Glands of external secretion that release its secretions to the body's cavities, organs, or surface, through a duct.Scent Glands: Exocrine glands in animals which secrete scents which either repel or attract other animals, e.g. perianal glands of skunks, anal glands of weasels, musk glands of foxes, ventral glands of wood rats, and dorsal glands of peccaries.Meibomian Glands: The sebaceous glands situated on the inner surface of the eyelids between the tarsal plates and CONJUNCTIVA.Salivary Glands: Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).Lacrimal Apparatus Diseases: Diseases of the lacrimal apparatus.Bodily Secretions: Endogenous substances produced through the activity of intact cells of glands, tissues, or organs.Arachnida: A class of Arthropoda that includes SPIDERS; TICKS; MITES; and SCORPIONS.Brunner Glands: The abundant submucosal mucous glands in the DUODENUM. These glands secrete BICARBONATE IONS; GLYCOPROTEINS; and PEPSINOGEN II.Salt Gland: A compound tubular gland, located around the eyes and nasal passages in marine animals and birds, the physiology of which figures in water-electrolyte balance. The Pekin duck serves as a common research animal in salt gland studies. A rectal gland or rectal salt gland in the dogfish shark is attached at the junction of the intestine and cloaca and aids the kidneys in removing excess salts from the blood. (Storer, Usinger, Stebbins & Nybakken: General Zoology, 6th ed, p658)Waxes: A plastic substance deposited by insects or obtained from plants. Waxes are esters of various fatty acids with higher, usually monohydric alcohols. The wax of pharmacy is principally yellow wax (beeswax), the material of which honeycomb is made. It consists chiefly of cerotic acid and myricin and is used in making ointments, cerates, etc. (Dorland, 27th ed)Sebaceous Glands: Small, sacculated organs found within the DERMIS. Each gland has a single duct that emerges from a cluster of oval alveoli. Each alveolus consists of a transparent BASEMENT MEMBRANE enclosing epithelial cells. The ducts from most sebaceous glands open into a HAIR FOLLICLE, but some open on the general surface of the SKIN. Sebaceous glands secrete SEBUM.Amphibian Venoms: Venoms produced by frogs, toads, salamanders, etc. The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. The venoms have been used as arrow poisons and include bufogenin, bufotoxin, bufagin, bufotalin, histrionicotoxins, and pumiliotoxin.Mucus: The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.Glue Proteins, Drosophila: Glycosylated proteins which are part of the salivary glue that Drosophila larvae secrete as a means of fixing themselves to an external substrate for the duration of the pre-pupal and pupal period.Genitalia, Male: The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).Sex Attractants: Pheromones that elicit sexual attraction or mating behavior usually in members of the opposite sex in the same species.Harderian Gland: A sebaceous gland that, in some animals, acts as an accessory to the lacrimal gland. The harderian gland excretes fluid that facilitates movement of the third eyelid.Submandibular Gland: One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)Salivary Proteins and Peptides: Proteins and peptides found in SALIVA and the SALIVARY GLANDS. Some salivary proteins such as ALPHA-AMYLASES are enzymes, but their composition varies in different individuals.Secretory Rate: The amount of a substance secreted by cells or by a specific organ or organism over a given period of time; usually applies to those substances which are formed by glandular tissues and are released by them into biological fluids, e.g., secretory rate of corticosteroids by the adrenal cortex, secretory rate of gastric acid by the gastric mucosa.Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.Fatty Alcohols: Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Pancreas, Exocrine: The major component (about 80%) of the PANCREAS composed of acinar functional units of tubular and spherical cells. The acinar cells synthesize and secrete several digestive enzymes such as TRYPSINOGEN; LIPASE; AMYLASE; and RIBONUCLEASE. Secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the DUODENUM.Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.Pancreatic Juice: The fluid containing digestive enzymes secreted by the pancreas in response to food in the duodenum.Somatostatin: A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.Radioimmunoassay: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.Eyelid DiseasesEyelids: Each of the upper and lower folds of SKIN which cover the EYE when closed.Heartwater Disease: A tick-borne septicemic disease of domestic and wild ruminants caused by EHRLICHIA RUMINANTIUM.Ehrlichia ruminantium: A species of gram-negative bacteria in the family ANAPLASMATACEAE, that causes HEARTWATER DISEASE in ruminants.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.rab GTP-Binding Proteins: A large family of MONOMERIC GTP-BINDING PROTEINS that play a key role in cellular secretory and endocytic pathways. EC 3.6.1.-.Reagent Kits, Diagnostic: Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.rab5 GTP-Binding Proteins: A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in transport from the cell membrane to early endosomes. This enzyme was formerly listed as EC 188.8.131.52.rab3 GTP-Binding Proteins: A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in calcium-dependent EXOCYTOSIS. This enzyme was formerly listed as EC 184.108.40.206.Adenosine: A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.Receptor, Serotonin, 5-HT1B: A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.Receptor, Serotonin, 5-HT2B: A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs. A number of functions have been attributed to the action of the 5-HT2B receptor including the development of cardiac myocytes (MYOCYTES, CARDIAC) and the contraction of SMOOTH MUSCLE.Receptor, Adenosine A2B: A subclass of adenosine A2 receptors found in the CECUM, the COLON, the BLADDER, and a variety of other tissues. It is generally considered to be a low affinity receptor for ADENOSINE that couples to the GS, STIMULATORY G-PROTEIN.Receptor, Adenosine A2A: A subclass of adenosine A2 receptors found in LEUKOCYTES, the SPLEEN, the THYMUS and a variety of other tissues. It is generally considered to be a receptor for ADENOSINE that couples to the GS, STIMULATORY G-PROTEIN.Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.Fatty Acids, Essential: Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.Mass Spectrometry: An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.Conjunctiva: The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Phosphates: Inorganic salts of phosphoric acid.Dry Powder Inhalers: A device that delivers medication to the lungs in the form of a dry powder.Buffers: A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer.Powder Diffraction: Method of using a polycrystalline powder and Rietveld refinement (LEAST SQUARES ANALYSIS) of X-RAY DIFFRACTION or NEUTRON DIFFRACTION. It circumvents the difficulties of producing single large crystals.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Calcium Phosphates: Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.
Mauduit, P; Herman, G; Rossignol, B (1984). "Protein secretion induced by isoproterenol or pentoxifylline in lacrimal gland: ... "Α1A-Adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries". British Journal of Pharmacology. 150 (1): ...
Chalazion* is a granuloma that forms in the eyelid due to blocked secretions from the meibomian gland. Inflammation of the ... Imperforate lacrimal punctum is a congenital disorder of dogs involving the lack of an opening to the nasolacrimal duct (tear ... Also common is Taenia pisiformis, spread by ingesting rabbits and rodents. Rare tapeworm infections are caused by species of ... The pituitary gland produces a hormone that signals the adrenal gland to produce cortisol; a tumor can cause it to produce the ...
Experimental Evidence of Fluid Secretion of Rabbit Lacrimal Gland Duct Epithelium You will receive an email whenever this ... Katona M Vizvári E Németh L Experimental evidence of fluid secretion of rabbit lacrimal gland duct epithelium. Invest ... Chuanqing Ding; Experimental Evidence of Fluid Secretion of Rabbit Lacrimal Gland Duct Epithelium. Invest. Ophthalmol. Vis. Sci ... The lacrimal gland (LG) is the major source of tears that lubricate, nourish, and protect the integrity and function of the eye ...
... Carlsson, Stina K. Linnaeus ... The lacrimal gland (LG) is an exocrine gland important for secretion of the tear film. The kinase p38 has important signal ... lacirmal gland, p38, secretion, acetylcholine National Category Cell Biology Research subject. Natural Science, Biomedical ... In conclusion, p38 activation mediates secretion in cholinergic stimulation of rabbit LG cells. ...
Nucleoside and Nucleotide Stimulation of Fluid Secretion in the Pigmented Rabbit Conjunctiva ... Lacrimal Gland and Ocular Surface: Signal Transduction, Membrane Traffic and Fluid and Protein Secretion. * Front Matter Pages ... Presence of α-and β-Integrin Subunits in Rabbit Lacrimal Gland Acinar Cells Cultured on a Laminin-Rich Matrix ... Identification of Androgen Receptors in Rabbit Lacrimal Gland by Immunohistochemsitry Mark D. Aupperlee, John T. Wertz, Kyle E ...
A decline in lacrimal gland fluid output can be a contributing... ... Lacrimal gland fluid secretion is essential for maintaining the ... D.A. Dartt, M. Moller, and J.H. Poulsen, Lacrimal gland electrolyte and water secretion in the rabbit: localization and role of ... A decline in lacrimal gland fluid output can be a contributing factor to dry eye disease. Lacrimal gland functional activity is ... Lacrimal gland fluid secretion is essential for maintaining the aqueous volume of the precorneal tear film and ocular surface ...
Exogenous Lac-ELPs promoted β-hexosaminidase secretion from rabbit lacrimal gland acinar cells (LGACs); evoked Ca2+ wave ... In vitro activities were tested using rabbit lacrimal gland acinar cells (LGACs) and SV40-immortalized human corneal epithelial ...
Characterization of beta-hexosaminidase secretion in rabbit lacrimal gland Exp Eye Res. 2006 Nov; 83(5):1081-8. . View in ... A lacrimal gland is a lacrimal gland, but rodents and rabbits are not human Ocul Surf. 2010 Jul; 8(3):111-34. . View in ... Androgen support of lacrimal gland function in the female rabbit Adv Exp Med Biol. 1998; 438:89-93. . View in PubMed ... Fluid phase endocytosis by isolated rabbit lacrimal gland acinar cells Exp Eye Res. 1995 May; 60(5):511-25. . View in PubMed ...
In many species serous lacrimal glands bind sex hormones and prolactin, have cells making immunoglobulins and growth factors, ... D. A. Dartt, M. Shulman, K.L. Gray, S.R. Rossi, C. Matkin, and J.P. Gilbard, Stimulation of rabbit lacrimal gland secretion ... D.A. Dartt, Signal transduction and control of lacrimal gland protein secretion: a review. Curr. Eye Res. 8:619 (1989).CrossRef ... In: Sullivan D.A., Stern M.E., Tsubota K., Dartt D.A., Sullivan R.M., Bromberg B.B. (eds) Lacrimal Gland, Tear Film, and Dry ...
Rab27b participates in aspects of lacrimal gland acinar cell secretory vesicle formation and release. ... Data indicate that the secretion of microRNA miR (show MLXIP ELISA Kits)-143, depends on rab (show HRB ELISA Kits) GTP-binding ... Rabbit RAB27B, Member RAS Oncogene Family (RAB27B) interaction partners * Rab27b enrichment occurs early in secretory vesicle ... Rab27b participates in aspects of lacrimal gland acinar cell secretory vesicle formation and release. ...
OBJECTIVE: We investigated the neural pathway for tear secretion from the lacrimal gland of New Zealand White rabbits. METHODS: ... The neural pathway for lacrimal gland tear secretion in New Zealand White rabbits. ... www.readbyqxmd.com/read/28396281/the-neural-pathway-for-lacrimal-gland-tear-secretion-in-new-zealand-white-rabbits ... Sanitized dry cotton swabs with menthol were used to wipe both of the rabbits eyelids in the irritant-stimulated group, and ...
... rabbit polyclonal, recognizes the ~28 kDa AQP 5 protein in epithelial tissue extracts. It is validated for ELISA, Western ... AQP5 is found in several epithelial tissues (salivary and lachrymal glands, corneal epithelium in the eye and lung). It is ... implicated in the generation of saliva, tears, and pulmonary secretions. Host. Rabbit. ... Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~28 kDa AQP5 protein. Background. Rat AQP5 is a 265 amino ...
... in which the lacrimal glands, Harderian gland, and nictitating membrane were removed, or for 4 weeks in the cat dry-eye model, ... The aim of this study was to evaluate the effect of gefarnate on mucin-like glycoprotein secretion in isolated rabbit ... in which the lacrimal gland and nictitating membrane were removed. Corneal epithelial damage was evaluated by measurement of ... Gefarnate stimulated mucin-like glycoprotein secretion in conjunctival tissue in a dose-dependent manner. In the rabbit dry-eye ...
... receptors as well as a role for them in lacrimal gland secretion, and especially in synergy with purinergic and cholinergic ... Rabbit Adenosine A2b Receptor (ADORA2B) interaction partners * Study reveals presence of adenosine A(2A) and A(2B (show ADRA2B ...
... receptors as well as a role for them in lacrimal gland secretion, and especially in synergy with purinergic and cholinergic ... Rabbit Adenosine A2b Receptor (ADORA2B) Interaktionspartner * Study reveals presence of adenosine A(2A) and A(2B (zeige ADRA2B ...
13Pholpramol C. Secretory effect of prostaglandins on the rabbit lacrimal gland in vivo. Prostaglandins Med 1979;3:185-192. ... HPLC/mass spectrometry studies have shown that the polar lipid profiles of meibomian gland secretions in female Sjögrens ... Correlations between nutrient intake and the polar lipid profiles of meibomian gland secretions in women with Sjogrens ... The oil glands in the eyelid are critical to tear film structure and eye comfort. TheraTears Nutrition for Dry Eyes provides a ...
Mauduit, P; Herman, G; Rossignol, B (1984). "Protein secretion induced by isoproterenol or pentoxifylline in lacrimal gland: ... "Α1A-Adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries". British Journal of Pharmacology. 150 (1): ...
Aqueous-deficient dry eye, which is a very common form, is primarily due to a lack of tear secretion from the lacrimal gland. ... meibomian gland. conjunctiva, cornea. iris/ciliarv body. lens and/or retina of humans. rats and/or rabbits. and the expression ... the lacrimal gland. meibomian gland. conjunctiva. goblet cells. cornea. anterior chamber. lens. vitreous and retina:- (2) ... lacrimal glands to secrete at least basal tear volumes: make available regions of functional lacrimal tissue, that might ...
Norepinephrine-responsive beta-adrenergic receptors in rabbit lacrimal gland.. 1973 S Y Botelho et al. American Journal of ... secretion, Norepinephrine, Pilocarpine,... ...
Direct visualization of aqueous tear secretion from lacrimal gland. Acta Ophthalmol. 2016 Nov 23. · Song IS, Yoon SY, Kim JY, ... Safety and efficacy of tacrolimus-coated silicone plates as an alternative to mitomycin C in a rabbit model of conjunctival ... Direct visualization of aqueous tear secretion from lacrimal gland. Acta Ophthalmol. 2017 Jun;95(4):e314-e322. · Song WS, Park ... 2009) · Endoscopic vitrectomy improved outcomes of Seoul-type keratoprosthesis exchange in rabbit model - Lee SM, Kim MK, Oh JY ...
The neural pathway for lacrimal gland tear secretion in New Zealand White rabbits. ... Rabbit Monoclonals. finally here. BCA Protein Assay. Cell Counting Kit (CCK-8). SDS-PAGE Electrophoresis Buffer. Tris-glycine- ... Custom Rabbit Polyclonal Antibody. Boster offers custom polyclonal antibody generation service starting at $800. The service ... Determination Of The Nerve Growth Factor Level In The Central Cornea After Lasik And Epi-Lasik Treatment In A Rabbit Model ...
Electrical Stimulation of the Lacrimal Gland in Rabbits Brinton, M., Chung, J., Kossler, A., Loudin, J., Ta, C., Palanker, D. V ... Chronic Electrical Stimulation for Tear Secretion: Lacrimal vs. anterior ethmoid nerve. The ocular surface Kossler, A. L., ... two rabbits for 6 months, two rabbits for 9 months, one rabbit for 12 months, and one rabbit for 16 months. Rabbits were ... Lacrimal gland and nasal septal tissue were evaluated histologically after chronic stimulation (2 weeks-7 months).RESULTS: LNS ...
Electrical Stimulation of the Lacrimal Gland in Rabbits Brinton, M., Chung, J., Kossler, A., Loudin, J., Ta, C., Palanker, D. V ... Implanted Microelectronic Stimulator Increases Tear Secretion in Rabbits Brinton, M., Chung, J., Kossler, A., Kook, K., Loudin ... two rabbits for 6 months, two rabbits for 9 months, one rabbit for 12 months, and one rabbit for 16 months. Rabbits were ... There were clear corneas in three of six rabbits that had implantation of hydrogel for 2 months. In the six rabbits with ...
The formation of the hair-centered dacryolith might be associated with the patients personal history of being a rabbit raiser ... Physical examination revealed an inflammatory granuloma in the lateral canthus and a fistula with purulent secretion. ... Here we report a case with a large lacrimal gland ductule stone with an unique hairy nucleus. A 38-year-old female presented ... After we incised the fistula, a huge dacryolith (10 mm × 5 mm × 3 mm) was identified at the end of the dilated lacrimal gland ...
... but only males displayed a loss of lacrimal gland secretory funct ion. The lack of lacrimal gland dysfunction in females may be ... As such, treatments for SjS can be optimized to either halt IL22 secretion from each cell type if its effects are shown to be ... Sections were cut to 5 m and stained using either anti IL 22 or anti IL or both antibodies were performed using rabbit IgG. ... we examine the lacrimal glands, spleen, thymus, and lymph nodes. Similar observations were made in the lacrimal glands of both ...
... preventing the lacrimal and the third eyelid glands reflex secretion, reducing tear production (Hamor et al., 2000). ... J.R. Influence of topical anesthesia on tear dynamics and ocular drug bioavailability in albino rabbits. J. Pharmac. Sci., v.64 ... Não ocorreram alterações na pressão intra-ocular, no diâmetro pupilar e na produção lacrimal. O colírio de tetracaína ... in rabbits (Seabaugh et al., 1993), 25 minutes in cats (Binder and Herring, 2006) and 25 minutes in horses (Kalf et al., 2008). ...
PURPOSE: Tear secretion from the main lacrimal gland (LG) is mainly regulated by parasympathetic nerves. We performed several ... Reinnervated nerves contribute to the secretion function and regeneration of denervated submandibular glands in rabbits. ... Fluid and ion secretion from the submandibular gland (SMG) is mainly regulated by parasympathetic nerves. This study evaluated ... Parasympathectomy increases resting secretion of the submandibular gland in minipigs in the long term. ...
Epithelial cellsExocrine GlandsHarderian GlandsSalivaStimulationInvest Ophthalmol Vis SciMeibomianKeratoconjunctivitisEpitheliaRole in lacrimalTearsExpressed in the salivaryFluidInfiltratesAqueousCorneaSalivary secretionInflammatoryPolyclonalConjunctivaAcinar cellMammaryConjunctivalMucusProteinDysfunctionOCULAR SURFACE DISEASEAutoimmuneVitroSecretory vesicleSurgicallyInnervationNictitating membrane were removedTissuesImmune-mediatedProteinsLymph nodesRose bengalGastricReceptorsExpressionMucousSweatGeneEndocrineSignificantly decreasedRegulationMucinsCellularMethodsAutonomicLactoferrinEbner'sMice
- In vitro activities were tested using rabbit lacrimal gland acinar cells (LGACs) and SV40-immortalized human corneal epithelial cells (HCE-T). In vitro Proclear TM contact lens retention was characterized by fluorescence detection. (arvojournals.org)
- A Rab11a-enriched subapical membrane compartment regulates a cytoskeleton-dependent transcytotic pathway in secretory epithelial cells of the lacrimal gland J Cell Sci. (usc.edu)
- Immunohistochemical and histochemical characterisation of epithelial cells of rabbit lacrimal glands in tissue sections and cell cultures, Tissue &.Cell 28: 301-312 (1996). (springer.com)
- Y. Chowers, L. Cahalon, M. Lahav, H. Schor, R. Tal, S. Bar-Meir, and M. Lévite, Somatostatin through its specific receptor inhibits spontaneous and TNF-_- and bacteria-induced IL-8 and IL-1 secretion from intestinal epithelial cells. (springer.com)
- Immunohistochemistry staining located NHE8 protein at the plasma membrane of the epithelial cells in the conjunctiva, the cornea, and the lacrimal gland both in human and mouse. (physiology.org)
- Mature epithelial cells in ectodermal secretory organs such as salivary and lacrimal glands have common characteristics, including a polarized columnar cell shape, close cell-cell adhesion, specialized intercellular junctions and an apico-basal polarity [ 9 , 11 ]. (ijbs.com)
- Sj?gren's syndrome (SjS) is a complex autoimmune disease which targets the exocrine glands resulting in xerostomia/ keratoconjunctivitis sicca. (ufl.edu)
- Sjögren's syndrome (SS) is a systemic autoimmune disease mainly affecting the exocrine glands, resulting in severe impairment of saliva and tear production. (biomedcentral.com)
- The nonobese diabetic (NOD) mouse strain exhibits immunological, histopathological and physiological characteristics of SS with focal mononuclear cell infiltration of the exocrine glands from approximately 8 weeks of age [ 7 ]. (biomedcentral.com)
- Selective innervation of different target tissues in guinea-pig cranial exocrine glands by sub-populations of parasympathetic and sympathetic neurons. (semanticscholar.org)
- This study has used multiple-labelling immunohistochemistry and quantitative analysis to examine the projections of subpopulations of parasympathetic and sympathetic neurons to different vascular and secretory structures in five cranial exocrine glands of guinea-pigs. (semanticscholar.org)
- Activated autoreactive B cells and T cells as well as increased levels of pro-inflammatory cytokines drive chronic inflammation of the exocrine glands, associated with loss of function ( 4 ). (frontiersin.org)
- N.F. Boas, and R.W. Bates, Role of the thyroid and anterior pituitary glands in the maintenance of the harderian glands of the rat. (springer.com)
- Experimental KCS with reduction of tear production was possible with surgical ablation of the lacrimal and harderian glands and nictitating membrane. (bjmu.edu.cn)
- Implicated in the generation of saliva, tears, and pulmonary secretions. (bosterbio.com)
- Lactoferrin is an iron-binding glycoprotein of the transferrin family that is expressed in most biologic fluids, such as the breast milk, particularly the colostrums, tears, sweat, saliva and other exocrine secretions of mammals. (mblintl.com)
- On the other hand, studies done on the effects of stress on the mucosal immunesystem have focused almost exclusively in relation to inflammatory diseases of the intestineand the secretion of IgA in saliva.The abundant information available confirms that psychological stress plays a fundamentalrole in the physiopathology and clinical symptoms of intestinal inflammatory diseases inhumans [9, (slideshare.net)
- Muscarinic receptor activation was followed by saliva secretion measurements. (biomedcentral.com)
- It is highly expressed in the salivary and mammary glands and secreted into saliva and milk. (biomedcentral.com)
- Thus the saliva, perspiration, tearsand other secretions may be augmented by quantities which are toosmall to act as emetics, though there is no question that these are dueto the commencing emetic action.apomorphine induces vomiting through changes in the medullaoblongata and not by irritation of the stomach. (deloachwatchservice.com)
- The results revealed activation of p38 mediated by Cch stimulation and inhibition of Cch-induced secretion as a result of p38 inhibition. (diva-portal.org)
- In conclusion, p38 activation mediates secretion in cholinergic stimulation of rabbit LG cells. (diva-portal.org)
- Accumulation of catalytically active proteases in lacrimal gland acinar cell endosomes during chronic ex vivo muscarinic receptor stimulation Scand J Immunol. (usc.edu)
- Altered traffic to the lysosome in an ex vivo lacrimal acinar cell model for chronic muscarinic receptor stimulation Exp Eye Res. (usc.edu)
- K. Yoshino, D. Monroy, and S. C. Pflugfelder, Cholinergic stimulation of lactoferrin and epidermal growth factor secretion by the human lacrimal gland, Cornea . (springer.com)
- D. A. Dartt, M. Shulman, K.L. Gray, S.R. Rossi, C. Matkin, and J.P. Gilbard, Stimulation of rabbit lacrimal gland secretion with biologically active peptides. (springer.com)
- Rab27b is associated with tubulovesicle membranes in the parietal cell and Rab27b may play a role in stimulation-associated membrane recruitment and gastric acid secretion. (antibodies-online.com)
- Tear secretion returned to baseline levels within 7 minutes after stimulation ended. (stanford.edu)
- stimulation of buy generic xanax 1.5mg online no prescription the protoplasm ofthe where to buy tramadol 50mg online no prescription salivary, lachrymal and sweat glands produces an increasein their secretions.8o constitutional ultram 200mg prescription or over the counter organic drugs.the central nervous system, after a very brief stage of primary stimulation, is powerfully depressed, especially the centresin the medulla. (fragrancefactory.ph)
- It found that while electrical stimulation of the lacrimal gland was effective at producing tears, stimulation of the afferent ethmoid nerve (nasal) pathway was more effective.2 Whats more, this latter stimulation activated other glands that secreted lipids and proteins, creating a more satisfying and natural dry eye treatment. (dryeyespecialist.com)
- Decreased vascular responses to salivary gland stimulation are observed in Sjögren's syndrome patients. (biomedcentral.com)
- We investigate whether impaired vascular responses to parasympathetic stimulation and muscarinic receptor activation in salivary glands parallels hyposalivation in an experimental model for Sjögren's syndrome. (biomedcentral.com)
- On the other hand, an in vitro study on human labial gland cells isolated from patients with primary SS has demonstrated similar response to stimulation with acetylcholine and neuropeptides as healthy controls, indicating functional receptor systems [ 9 ]. (biomedcentral.com)
- Diverse mediators modulate the chloride ion fluxes that drive lacrimal fluid production Invest Ophthalmol Vis Sci. (usc.edu)
- Adeno-associated virus-mediated IL-10 gene transfer suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis Invest Ophthalmol Vis Sci. (usc.edu)
- Cytopathology and exocrine dysfunction induced in ex vivo rabbit lacrimal gland acinar cell models by chronic exposure to histamine or serotonin Invest Ophthalmol Vis Sci. (usc.edu)
- Interacting influences of pregnancy and corneal injury on rabbit lacrimal gland immunoarchitecture and function Invest Ophthalmol Vis Sci. (usc.edu)
- P. Iserovich, Z. Wang, R.W. Beuerman, P.S. Reinach, and J. Fischbarg, Modulation of fluid transport by EGF and ET-1 in cultured rabbit lacrimal gland cells, Invest Ophthalmol Vis Sci 40: S539 (1999). (springer.com)
- P. Seifert, and M. Spitznas, Immunocytochemical and ultrastructural evaluation of the distribution of nervous tissue and neuropeptides in the meibomian gland. (springer.com)
- J.M. Tiffany, Physiological functions of the meibomian glands. (springer.com)
- J.V. Jester, N. Nicolaides, and R.E. Smith, Meibomian gland studies: histologic and ultrastructural investigations. (springer.com)
- such as when people cry for sadness or joy: and the meibomian glands, which are located behind the eyelashes and release the oily lipid layer. (rpbusa.org)
- The second type of dry ere is called evaporative and is typically caused by meibomian gland dysfunction and lipid insufficiency. (rpbusa.org)
- It has been estimated that meibomian gland disease, which also occurs in Sjogren's syndrome, may be a contributing factor in 60 to 80% of dry eye patients. (rpbusa.org)
- and a major reason why there are no cures for these dry eve syndromes today is that we have only begun to understand the nature of gender's impact on the eye, as well as the processes that control the lacrimal and meibomian glands, in both health and disease. (rpbusa.org)
- Ocular GVHD affects 40% to 60% of allogeneic SCT recipients and is characterized by dysfunction of lacrimal glands and Meibomian glands, resulting in dry eye syndrome due to reduced tear production and excessive evaporation of tears. (bloodadvances.org)
- 3 The histopathological features of ocular chronic GVHD include fibrosis and inflammatory cellular infiltration in the glandular interstitium of the lacrimal glands and fibrosis and atrophy of the Meibomian glands, indicating that a novel antifibrotic therapy could be beneficial for patients suffering from ocular GVHD. (bloodadvances.org)
- Long-term topical cyclosporine treatment improves tear production and reduces keratoconjunctivitis in rabbits with induced autoimmune dacryoadenitis J Ocul Pharmacol Ther. (usc.edu)
- Autoimmune dacryoadenitis and keratoconjunctivitis induced in rabbits by subcutaneous injection of autologous lymphocytes activated ex vivo against lacrimal antigens J Autoimmun. (usc.edu)
- Purpose: To establish a rabbit model for keratoconjunctivitis sicca (KCS) to study autologous submandibular gland transfer for treating severe KCS. (bjmu.edu.cn)
- Establishment of a Rabbit Model for Keratoconjunctivitis Sicca[J]. CORNEA,2011,30(9):1024-1029. (bjmu.edu.cn)
- Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized by keratoconjunctivitis sicca, xerostomia, and lymphocytic infiltration of salivary and lacrimal glands ( 1 , 2 ). (frontiersin.org)
- 2 . A composition for treating and/or preventing at least one disease selected from the group consisting of keratoconjunctivitis sicca, lacrimal hyposecretion, xerophthalmia, dry eye, age-related xerophthalmia, Stevens-Johnson syndrome, corneal epithelial disorder, corneal epithelial detachment and keratoconjunctival ulcer, said composition comprising a selective β 2 adrenergic receptor agonist as an active ingredient. (google.com)
- Keratoconjunctivitis sicca (dry-eye) is caused by insufficient tear production following disease of the tear glands. (ufaw.org.uk)
- At least five AQPs are expressed in the eye: AQP0(MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. (bosterbio.com)
- It was expressed in normal corneal and conjunctival epithelia but not in lacrimal glands. (bmj.com)
- Mucins are major components in mucus secretions and apical cell membranes on wet-surfaced epithelia. (pubmedcentralcanada.ca)
- The lacrimal gland (LG) is the major source of tears that lubricate, nourish, and protect the integrity and function of the eye, most notably the ocular surface. (arvojournals.org)
- Tears originate from several glands and form a film on the surface of the eye. (rpbusa.org)
- Using a chronic implant, we evaluate the effects of stimulating the anterior ethmoid nerve on the aqueous, lipid, and protein content of secreted tears.Neurostimulators were implanted beneath the nasal mucosa in 13 New Zealand white rabbits. (stanford.edu)
- 5.3 Lacrimal fluid (tears) 7.4 the role of isotonicity: tonicity refers to the osmotic pressure exerted by salts in aq. (pharmainfo.net)
- 10 . The method of claim 9 , wherein said improved tear secretion involves an increase in tear secretion level and/or protein concentration in tears. (google.com)
- The common breed-associated KCS being discussed in this document is an immune -mediated disease leading to progressive destruction of the lacrimal and nictitans glands which produce the aqueous (water) part of tears (Renwick 1996, Herring 2004). (ufaw.org.uk)
- Very often the nausea passes off imme-diately after the evacuation of tramadol buy usa the stomach, but when larger quantitieshave been administered, repeated vomiting and retching may occur.occasionally depression and sleep follow the emesis after even smalldoses.the attendant symptoms are profuse salivation, increased secretionof the mucous glands of the nose, throat and bronchial passages, tears,and a cold perspiration. (plantar-fasciitis-elrofeet.com)
- Katona M Vizvári E Németh L Experimental evidence of fluid secretion of rabbit lacrimal gland duct epithelium. (arvojournals.org)
- Lacrimal gland fluid secretion is essential for maintaining the aqueous volume of the precorneal tear film and ocular surface health. (springer.com)
- A decline in lacrimal gland fluid output can be a contributing factor to dry eye disease. (springer.com)
- However, there have been no direct studies on the role of EGF in lacrimal gland fluid transport regulation. (springer.com)
- In summary, parasympathectomy increases resting secretion of the SMGs in the long term with a possible mechanism involving improved transepithelial fluid transport. (bvsalud.org)
- METHODS Immunoblot analysis using either a rabbit polyclonal or a mouse monoclonal antibody against galectin-3 was employed to detect galectin-3 in tear fluid. (bmj.com)
- Pancreatic ductal HCO 3 - and fluid secretion were studied on pancreatic ducts isolated from wild-type (WT) and AQP1 knock out (KO) mice using microfluorometry and videomicroscopy, respectively. (frontiersin.org)
- In vivo pancreatic fluid secretion was estimated by magnetic resonance imaging. (frontiersin.org)
- HCO 3 - and fluid secretion significantly decreased in AQP1 KO versus WT mice and the absence of AQP1 also worsened the severity of pancreatitis. (frontiersin.org)
- Our results suggest that AQP1 plays an essential role in pancreatic ductal fluid and HCO 3 - secretion and decreased expression of the channel alters fluid secretion which probably contribute to increased susceptibility of the pancreas to inflammation. (frontiersin.org)
- hello anil , i hv some question for you What is the role of isotonicity in eye preparations and what isotonicity can be tolerate by eye without induce any discomfort and is the lachrymal fluid isotonic with blood? (pharmainfo.net)
- Is lacrimal fluid is isotonic with blood 3. (pharmainfo.net)
- Lacrimal fluid is isotonic with blood,having an isotonicity value corresponding to that of a 0.9%sodium chloride solution. (pharmainfo.net)
- The cerebrospinal fluid slowly flows toward the fourth ventricle by secretion pressure and passes into the spinal cord. (studyadda.com)
- Pregnancy probabilistically augments potential precursors to chronic, immune-mediated or autoimmune lacrimal gland infiltrates Ocul Surf. (usc.edu)
- Finally, research shows that inhibition of ICAM-1 and LFA-1 in mice reduces the number of inflammatory infiltrates in the lacrimal gland. (reviewofoptometry.com)
- In nonobese diabetic mice, salivary gland parasympathetic nerve fibres were absent in areas of focal infiltrates. (biomedcentral.com)
- The histopathological hallmarks of the disease are T-cell-dominated and B-cell-dominated focal infiltrates in the salivary glands. (biomedcentral.com)
- Aqueous-deficient dry eye, which is a very common form, is primarily due to a lack of tear secretion from the lacrimal gland. (rpbusa.org)
- An example would be Sjdgren's syndrome, an autoimmune disease wherein the body's immune system attacks and may eventually destroy the aqueous tear-producing cells (i.e.. epithelial) of the lacrimal gland. (rpbusa.org)
- Autoimmune dacryoadenitis and sialadenitis induced in rabbits by intravenous injection of autologous lymphocytes activated ex vivo against lacrimal antigens Cornea. (usc.edu)
- Distinct dacryoadenitides autoadoptively transferred to rabbits by different subpopulations of lymphocytes activated ex vivo Cornea. (usc.edu)
- Furthermore, DRA expression in NHE8−/− mice was reduced in the conjunctiva, the cornea, and the lacrimal glands in association with a reduction in conjunctival mucosal pH. (physiology.org)
- The results showed that the resting salivary secretion of SMGs decreased by 82.9% of that in control at 2 months after denervation, but increased by 156% at 6 months. (bvsalud.org)
- It has been suggested that the decrease in salivary flow follows the occurrence of focal lymphoid infiltration, with a considerable delay in time, and that the sole destruction or replacement of glandular tissue by inflammatory cells is not sufficient to explain the severe impairment in salivary secretion [ 1 ]. (biomedcentral.com)
- In the salivary glands, blood flow and salivary secretion are under autonomic nervous control of both parasympathetic and sympathetic nerves [ 5 ]. (biomedcentral.com)
- The manifestations of overt SS hallmarked by impaired lacrimal and salivary secretion are thought to develop later in life [ 1 ]. (biomedcentral.com)
- Multiple Natural and Experimental Inflammatory Rabbit Lacrimal Gland PhenotypesOcul Surf. (usc.edu)
- Physical examination revealed an inflammatory granuloma in the lateral canthus and a fistula with purulent secretion. (biomedcentral.com)
- a Prolapsed lacrimal gland (black arrow) and an inflammatory granuloma with a fistula (white arrow) with purulent secretion. (biomedcentral.com)
- These activated CD4+ effector T-cells migrate from the lymph nodes to the ocular surface and lacrimal glands, where they exert inflammatory effects. (reviewofoptometry.com)
- Anti-Aquaporin 5, rabbit polyclonal, recognizes the ~28 kDa AQP 5 protein in epithelial tissue extracts. (emdmillipore.com)
- Rabbit IgG polyclonal antibody for Aquaporin-5(AQP5) detection. (bosterbio.com)
- Three Rabbit Polyclonal to RPAB1 different sample preparations were made for each treatment (i.e. (kn-62.com)
- It has been Rabbit Polyclonal to OR10J5 found by several researchers the RIBE is present in both 3D human being tissue models and animal models, with endpoints including DNA harm, gene appearance dysregulation, cell loss of life, tumorigenesis, etc. [3C (researchassistantresume.com)
- Another study [ 26 ] established a DE model in rabbits by burning the bulbar conjunctiva with 50% trichloroacetic acid then surgically removing the lacrimal gland, Harderian gland, and nictitating membrane. (biomedcentral.com)
- itmay, perhaps, be explained by the arrest of the ordinary secretions ofthe lachrymal gland and conjunctiva in these cases. (boyhoodstudies.com)
- At the ocular surface, the major gel-forming mucin expressed by the goblet cells of the conjunctiva is MUC5AC, whereas a small nonpolymeric mucin, MUC7, is expressed by acinar cells of the lacrimal gland. (pubmedcentralcanada.ca)
- The most typicaleffects are obtained by the intravenous injection of the extract, but1 the other known galactagogues are extracts of the zolpiem prescription free corpus luteum, pineal gland, invol-uting uterus, and of the lactating mammary gland itself, and these are ambien pregnancy less powerfulthan pituitary extract.384 substances acting after absorptionsubcutaneous injection also elicits them in a less marked degree. (performancetechnician.com)
- The aim of this study was to evaluate the effect of gefarnate on mucin-like glycoprotein secretion in isolated rabbit conjunctival tissue, and on corneal epithelial damage in rabbit and cat dry-eye models. (dovepress.com)
- Conjunctival tissue isolated from rabbits was treated with gefarnate. (dovepress.com)
- Gefarnate stimulated mucin-like glycoprotein secretion in conjunctival tissue in a dose-dependent manner. (dovepress.com)
- These results suggest that gefarnate stimulates in vitro secretion of mucin-like glycoprotein in conjunctival tissue and ameliorates corneal epithelial damage in animal dry-eye models. (dovepress.com)
- Unusually, conjunctival redness could be due to lacrimal gland ductule dacryolith. (biomedcentral.com)
- Bartholin g's two small mucus-secreting glands, one on each side in the lower pole of the labium majus and connected to the surface by a duct lined with transitional cells, which opens just external to the hymenal ring. (thefreedictionary.com)
- cardiac g's mucus-secreting glands of the cardiac part (cardia) of the stomach. (thefreedictionary.com)
- It is influenced by the secretions' electrolyte, protein, and mucus contents. (molvis.org)
- Lacrimal gland functional activity is dependent on a host of neurohumors and cytokines that control its cells growth, differentiation and protein secretory activity. (springer.com)
- H. Marechal, H. Jammes, B. Rossignol, and P. Mauduit, EGF receptor mRNA and protein in rat lacrimal acinar cells: evidence of its EGF-dependent phosphotyrosylation, Am J Physiol 270: C1164-74 (1996). (springer.com)
- We use viral vectors to express the protein of interest in native or mutated form, and we then study the effects on secretion. (usc.edu)
- Furthermore we found that the eotaxin-1-dependent MMP-3 protein secretion was regulated by phospholipase C (PLC)-protein kinase C (PKC) cascade and c-Jun N-terminal kinase (JNK)/mitogen-activated protein (MAP) kinase pathways. (biomedcentral.com)
- Eotaxin-1 not only induces MMP-3 gene expression but also promotes MMP-3 protein secretion through G protein-coupled eotaxin-1 receptor activities. (biomedcentral.com)
- Expression of TNF inhibitor gene in the lacrimal gland promotes recovery of tear production and tear stability and reduced immunopathology in rabbits with induced autoimmune dacryoadenitis J Autoimmune Dis. (usc.edu)
- Nandoskar P., Parsa L. , Wang Y., Mircheff AK, Schechter JE, Thomas PB, Tronsdale MD, Ding C. Ion Transporters in Rabbit Lacrimal Acinns-Duct Axis and Their Changes in Induced Autoimmune Dacryoadenitis. (fallsmedicalspecialists.com)
- The nature of this hormone-induced immune response was dependent upon the autoimmune strain, and was not duplicated within lacrimal cells of nonautoimmune BALB/c mice. (kn-62.com)
- The aim of the current study was to investigate the role of p38 in carbachol (Cch)-induced LG secretion in LG acinar cells in vitro. (diva-portal.org)
- Impairs TLR-mediated in Tamsulosin Vitro Antibody Secretion and B Cell Proliferation To determine the mechanistic basis from the faulty TI-1 antibody replies in cKO mice we. (immune-source.com)
- After we incised the fistula, a huge dacryolith (10 mm × 5 mm × 3 mm) was identified at the end of the dilated lacrimal gland ductule and was removed surgically. (biomedcentral.com)
- In group A, the lacrimal gland, Harderian gland, and nictitating membrane of the left eyes were surgically removed. (biomedcentral.com)
- S. Tsukahara and D.M. Jacobowitz, Peptidergic innervation of the rat Harderian gland. (springer.com)
- METHODS: In male rabbits, we performed a retrograde dye-tracing study of LG innervation, evaluated preganglionic parasympathetic denervation, and administered glial cell-derived neurotrophic factor (GDNF) in the surgical area after parasympathetic denervation. (bvsalud.org)
- Gefarnate ointment was topically applied to eyes once daily for 7 days in the rabbit dry-eye model, in which the lacrimal glands, Harderian gland, and nictitating membrane were removed, or for 4 weeks in the cat dry-eye model, in which the lacrimal gland and nictitating membrane were removed. (dovepress.com)
- When cancer cells become invasive, they express many neuronal-type proteins, including those involved in electrical signaling, secretion, and motility. (usc.edu)
- Mammalian galectins at present comprise nine proteins sharing the property of secretion via a non-classic pathway and cation independent binding capacity to β-galactosides, including histoblood A and B group saccharides and poly-N-acetyl-lactosamines. (bmj.com)
- Interestingly, in the C57BL/6.NOD-Aec1R1Aec2 mouse model (currently considered one of the most phenotypically similar to the human disease) minimal to no IL-22 was present within the salivary or lacrimal glands, and levels present within the spleen, thymus, and lymph nodes were comparable to that of C57BL/6 controls. (ufl.edu)
- The lymph nodes are sometimes called lymph glands but are not glands in the usual sense. (thefreedictionary.com)
- 1-3 Furthermore, rat lacrimal acinar cells possess EGF receptors, 4 suggesting that these cells respond to EGF. (springer.com)
- M.E. Mato, M. Puig-Domingo, O. Fornas, and S.M. Webb, Expression of the somatostatin gene and receptors in the rat harderian gland. (springer.com)
- Norepinephrine-responsive beta-adrenergic receptors in rabbit lacrimal gland. (naver.com)
- The p38δ isoform was shown to have robust expression both by Western blotting of acinar cells and immunofluorescence of the whole gland. (diva-portal.org)
- N. Ishida, J. Maruo, and S. Mita, Expression and characterization of lacrimal gland water channels in Xenopus oocytes, Biochem Biophys Res Commun . (springer.com)
- We investigated the effects of the CC chemokine eotaxin-1 (CCL11) on the matrix metalloproteinase (MMP) expression and secretion in the human chondrocyte cell line SW1353 and primary chondrocytes. (biomedcentral.com)
- After ocular instillation, VA-lip HSP47 was distributed to the lacrimal glands, knocked down HSP47 expression in fibroblasts, reduced collagen deposition, and restored tear secretion after allogeneic SCT. (bloodadvances.org)
- Differential gene expression and immune localization of the orexin system in the major salivary glands of pigs. (semanticscholar.org)
- The expression of CA VI is not restricted only to the salivary glands. (biomedcentral.com)
- Hence, sialorphin is an exocrine and endocrine peptide-signal, whose expression is under activational androgenic regulation and secretion is evoked under adrenergic-mediated response to environmental stress, in male rat (Rougeot et al. (allindianpatents.com)
- A reduction in Dpysl4 gene expression in the tooth germ produced a loss of ameloblasts, resulting in the decrease of synthesis and secretion of enamel. (ijbs.com)
- The cold perspiration observed in poisoning may be ascribedto the collapse rather than to any direct action on the sweat glands,although aubert states that aconitine is a powerful diaphoretic initself.aconitine sometimes reduces the temperature both in fever and innormal animals, but the precise way in which this action is elicited isunknown. (granpallars.com)
- eccrine gland one of the ordinary or simple sweat glands , which are of the merocrine type. (thefreedictionary.com)
- The kinase p38 has important signal transduction functions, e.g. in gene transcription, but has previously not been known to modulate exocrine secretion. (diva-portal.org)
- Conclusions Our findings support our hypothesis and indicate a major part for the lacrimal gland microenvironment in mediating androgen effects on immune gene manifestation. (kn-62.com)
- CGS 35066 4C12 lacrimal glands/test/treatment/stress) and processed for evaluation of gene appearance. (kn-62.com)
- Molecular Biological Techniques To look for the aftereffect of T on lacrimal gland gene appearance, total RNA was isolated from lacrimal tissue using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) and purified with RNAqueous spin columns (Ambion, Austin, TX, USA). (kn-62.com)
- This extensive software program created gene ontology, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and = 15C18/sex/stress),30 and 14 days of T or P treatment of nonautoimmune, ovariectomized BALB/c mice (= 5C6 mice/condition/test),31 on lacrimal gland gene appearance. (kn-62.com)
- Outcomes T Impact on Gene Appearance in Lacrimal Glands of Feminine MRL/lpr and NOD Mice To look for the aftereffect of androgen treatment on gene appearance in lacrimal. (kn-62.com)
- In a genomic' approach, an androgen-regulated gene, which is predominantly expressed in the submandibular gland (SMG) and prostate of adult rats, has been identified (Rosinski-Chupin et al. (allindianpatents.com)
- Silencing of the exocytotic RAB (show HRB ELISA Kits ) family members RAB27A (show RAB27A ELISA Kits ) or RAB27B halted miR23b and miR921 secretion and reduced cellular invasion. (antibodies-online.com)
- Another related area of interest of the laboratory is the cellular mechanism of abnormal secretion and cell death in diabetes mellitus. (usc.edu)
- of several immune-related genes, ontologies, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways in lacrimal glands of MRL/lpr and NOD mice. (kn-62.com)
- 7C18 mice/condition) were killed by CO2 inhalation and exorbital lacrimal glands were eliminated for molecular biological procedures. (kn-62.com)
- Lacrimal cells samples were prepared by combining glands from two to six mice/strain/group. (kn-62.com)