Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
The body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components.
A family of angiogenic proteins that are closely-related to VASCULAR ENDOTHELIAL GROWTH FACTOR A. They play an important role in the growth and differentiation of vascular as well as lymphatic endothelial cells.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.
Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.
A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
Tumors or cancer of the PARATHYROID GLANDS.
Steroids with a hydroxyl group at C-3 and most of the skeleton of cholestane. Additional carbon atoms may be present in the side chain. (IUPAC Steroid Nomenclature, 1987)
Pathological processes of the PARATHYROID GLANDS. They usually manifest as hypersecretion or hyposecretion of PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.
A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
A family of closely related nerve growth factors that promote NEURON survival. They bind to GDNF RECEPTORS and stimulate SIGNAL TRANSDUCTION through PROTO-ONCOGENE PROTEIN C-RET.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.
Factors which enhance the growth potentialities of sensory and sympathetic nerve cells.
A neurotrophic factor that promotes the survival of various neuronal cell types and may play an important role in the injury response in the nervous system.
The mallow family of the order Malvales, subclass Dilleniidae, class Magnoliopsida. Members include GOSSYPIUM, okra (ABELMOSCHUS), HIBISCUS, and CACAO. The common names of hollyhock and mallow are used for several genera of Malvaceae.
Food products manufactured from fish (e.g., FISH FLOUR, fish meal).
An international agreement of the World Medical Association which offers guidelines for conducting experiments using human subjects. It was adopted in 1962 and revised by the 18th World Medical Assembly at Helsinki, Finland in 1964. Subsequent revisions were made in 1975, 1983, 1989, and 1996. (From Encyclopedia of Bioethics, rev ed, 1995)
The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.
Marine fish and shellfish used as food or suitable for food. (Webster, 3d ed) SHELLFISH and FISH PRODUCTS are more specific types of SEAFOOD.
A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
An advisory group composed primarily of staff physicians and the pharmacist which serves as the communication link between the medical staff and the pharmacy department.
Blood-coagulation factor VIII. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.
Storage-stable glycoprotein blood coagulation factor that can be activated to factor Xa by both the intrinsic and extrinsic pathways. A deficiency of factor X, sometimes called Stuart-Prower factor deficiency, may lead to a systemic coagulation disorder.
The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.
Endogenous substances, usually proteins, that are involved in the blood coagulation process.
Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).
Laboratory tests for evaluating the individual's clotting mechanism.
Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)
Critical analyses of books or other monographic works.
A broad category of nuclear proteins that are components of or participate in the formation of the NUCLEAR MATRIX.
Endoscopic examination, therapy or surgery of the female pelvic viscera by means of an endoscope introduced into the pelvic cavity through the posterior vaginal fornix.
The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
A common primary headache disorder, characterized by a dull, non-pulsatile, diffuse, band-like (or vice-like) PAIN of mild to moderate intensity in the HEAD; SCALP; or NECK. The subtypes are classified by frequency and severity of symptoms. There is no clear cause even though it has been associated with MUSCLE CONTRACTION and stress. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Functional importance and local environments of the cysteines in the tetracycline resistance protein encoded by plasmid pBR322. (1/1266)

The properties of the cysteines in the pBR322-encoded tetracycline resistance protein have been examined. Cysteines are important but not essential for tetracycline transport activity. None of the cysteines reacted with biotin maleimide, suggesting that they are shielded from the aqueous phase or reside in a negatively charged local environment.  (+info)

Phage type conversion in Salmonella enterica serotype Enteritidis caused by the introduction of a resistance plasmid of incompatibility group X (IncX). (2/1266)

The plasmid pOG670, a 54 kb, conjugative plasmid that specifies resistance to ampicillin and kanamycin and belonging to the incompatibility group X (IncX), was transferred into 10 isolates of Salmonella enterica serotype Enteritidis belonging to 10 different phage types (PT1, 2, 3, 4, 8, 9, 9b, 10, 11 and 13). Acquisition of the plasmid by these strains did not result in the loss of any resident plasmids but resulted in phage type conversion in 8 of the 10 strains (PT1, 2, 4, 8, 9, 9b, 10 and 11). The observed changes in phage type were found to result from the loss of sensitivity to 3 of the 10 typing phages used (phages 3, 5 and 7). Where the conversion resulted in a change to a defined phage type, both the new and original PTs belonged to the same, previously described, evolutionary lines. Enteritidis PTs 1, 4 and 8, commonly associated with poultry world-wide, were converted to PTs 21, 6 and 13a respectively. The results indicate a different route for phage type conversion Enteritidis from others reported in the literature and, although IncX plasmids are not normally present in PT8 or PT13a, may suggest a possible mechanism/link connecting these phage types.  (+info)

An explanation for the apparent host specificity of Pseudomonas plasmid R91 expression. (3/1266)

Pseudomonas aeruginosa strain 9169 has been reported to contain a plasmid that expresses resistance to carbenicillin (Cb), kanamycin (Km), and tetracycline (Tc) in Escherichia coli but resistance only to Cb in certain Pseudomonas recipients. The triply resistant plasmid in E. coli belonged to incompatibility (Inc) group P or P-1, whereas the singly resistant plasmid in P. aeruginosa was compatible with IncP-1 plasmids and other plasmids of established Inc specificity but incompatible with plasmid pSR1 that is here used to define a new Pseudomonas Inc group P-10. Additional physical and genetic studies showed that strain 9169 contained not one but two plasmids: IncP-1 plasmid R91a, determining the Cb Km Tc phenotype, and IncP-10 plasmid R91, determining Cb that differed in molecular weight and in EcoRI and BamHI restriction endonuclease recognition sites. Plasmid multiplicity rather than host effects on plasmid gene expression can account for differences in the phenotype of strain 9169 transconjugants to E. coli and P. aeruginosa.  (+info)

R-factor inheritance and plasmid content in mucoid Pseudomonas aeruginosa. (4/1266)

Eighteen strains of alginate-producing mucoid Pseudomonas aeruginosa were evaluated with respect to plasmid content and the ability to maintain well-characterized R plasmids. The spontaneous loss of alginate production in these strains varied from 0.01 to 0.7% and was not significantly increased by plasmid curing regimens. Examination of cleared lysates of these strains and their isogenic nonmucoid derivatives by agarose gel electrophoresis failed to reveal plasmid DNA. R-plasmid (P-incompatibility-group) transfer to mucoid P. aeruginosa was unaffected by the presence of the alginate capsule. Maintenance and expression of such plasmids in the mucoid strains were confirmed by agarose gel electrophoresis and by verification of plasmid-linked drug resistance and pilus-specific bacteriophage sensitivity. These studies demonstrate that alginate production does not appear to be plasmid linked and that mucoid P. aeruginosa are capable of receiving and donating certain drug resistance plasmids. Since some of the plasmids used here have been shown to mobilize chromosomal DNA, strains constructed in this study should afford the means for exploring the genetic basis of the mucoid phenotype.  (+info)

Immunochemical studies on R mutants of Yersinia enterocolitica O:3. (5/1266)

Three mutants of Yersinia enterocolitica O:3, namely: YeO3-R1, YeO3-RfbR7 and YeO3-c-trs8-R were classified on the basis of sodium dodecyl sulphate/polyacrylamide gel electrophoresis (SDS/PAGE) profile of isolated lipopolysaccharides (LPS) as belonging to the Ra- (the first) and the Rc-type (the other two mutants). Methylation analysis, in addition to 13C and 1H NMR studies of purified core oligosaccharides revealed structures similar to those established previously for the full core of Y. enterocolitica O:3 in the case of the Ra mutant, and identical to that reported for the Rc mutant Ye75R, in the case of the two other mutants. The O-specific sugar, 6d-L-altrose, which forms a homopolymeric O-chain, was present in small amounts in all three LPS preparations, as well as in the core oligosaccha ride preparations along with the Ra and the Rc sugars, characteristic of the Y. enterocolitica O:3 core. This result is in line with genetic data, indicating that it is the inner core region which is the receptor for the O-specific chain in Y. enterocolitica O:3. This region seems likewise to be the anchoring region for the enterobacterial common antigen (ECA), as shown by SDS/PAGE/Western blot analysis with monoclonal antibodies against ECA. In addition, we also demonstrated that the Ye75R mutant Rc and its parental strain Ye75S, both were ECA-immunogenic strains. So far, ECA-immunogenic strains, i.e. those with LPS-linked ECA, were only identified in E. coli mutants of the R1, R4 and K-12 serotype.  (+info)

Comparison of proteins involved in pilus synthesis and mating pair stabilization from the related plasmids F and R100-1: insights into the mechanism of conjugation. (6/1266)

F and R100-1 are closely related, derepressed, conjugative plasmids from the IncFI and IncFII incompatibility groups, respectively. Heteroduplex mapping and genetic analyses have revealed that the transfer regions are extremely similar between the two plasmids. Plasmid specificity can occur at the level of relaxosome formation, regulation, and surface exclusion between the two transfer systems. There are also differences in pilus serology, pilus-specific phage sensitivity, and requirements for OmpA and lipopolysaccharide components in the recipient cell. These phenotypic differences were exploited in this study to yield new information about the mechanism of pilus synthesis, mating pair stabilization, and surface and/or entry exclusion, which are collectively involved in mating pair formation (Mpf). The sequence of the remainder of the transfer region of R100-1 (trbA to traS) has been completed, and the complete sequence is compared to that of F. The differences between the two transfer regions include insertions and deletions, gene duplications, and mosaicism within genes, although the genes essential for Mpf are conserved in both plasmids. F+ cells carrying defined mutations in each of the Mpf genes were complemented with the homologous genes from R100-1. Our results indicate that the specificity in recipient cell recognition and entry exclusion are mediated by TraN and TraG, respectively, and not by the pilus.  (+info)

Molecular epidemiological study on tetracycline resistance R plasmids in enterohaemorrhagic Escherichia coli O157:H7. (7/1266)

Restriction patterns obtained with EcoRI and Southern hybridization were used for the differentiation of tetracycline-resistant (Tet(r)) R plasmids in enterobaemorrhagic Escherichia coli (EHEC) O157:H7 isolates from a mass outbreak at a kindergarten in Obihiro-City, Hokkaido, Japan, 1996. Two kinds of Tet(r) R plasmids of 50 and 95 kb were detected. The 50-kb plasmids were identical to each other, while the 93-kb plasmids were of three types that were very similar to each other. The tet genes of both 50- and 95-kb R plasmids were 100% identical to the tet gene of pSC101 and all plasmids hybridized to a probe for tet. Because food-origin O157 strains were sensitive to tetracycline, we concluded that such Tet(r) R-plasmids might transfer to drug-sensitive O157 strains in the infected individuals.  (+info)

Propagation of TEM- and PSE-type beta-lactamases among amoxicillin-resistant Salmonella spp. isolated in France. (8/1266)

A survey conducted between 1987 and 1994 at the University Hospital of Besancon, France, demonstrated a dramatic increase (from 0 to 42. 5%) in the prevalence of amoxicillin resistance among Salmonella spp. Of the 96 resistant isolates collected during this period (including 77 Typhimurium), 54 were found to produce TEM-1 beta-lactamase, 40 produced PSE-1 (equivalent to CARB-2), one produced PSE-1 plus TEM-2, and one produced OXA-1 in isoelectric focusing and DNA hybridization experiments. Plasmids coding for these beta-lactamases were further characterized by (i) profile analysis, (ii) restriction fragmentation pattern analysis, (iii) hybridization with an spvCD-orfE virulence probe, and (iv) replicon typing. In addition, isolates of S. typhimurium were genotypically compared by pulsed-field gel electrophoresis of XbaI-macrorestricted chromosomal DNA. Altogether, these methods showed that 40 of the 41 PSE-1 producers were actually the progeny of a single epidemic S. typhimurium strain lysotype DT104. Isolates of that strain were found to harbor RepFIC virulence plasmids with somewhat different restriction profiles, but which all carried the bla(PSE-1) gene. Of these virulence/resistance plasmids, 15 were transmissible to Escherichia coli. TEM-1-producing S. typhimurium displayed much greater genotypic and plasmidic diversities, suggesting the acquisition of the bla(TEM-1) gene from multiple bacterial sources by individual strains. In agreement with this, 32 of the 35 S. typhimurium plasmids encoding TEM-1 were found to be conjugative. These data show that development of amoxicillin resistance among Salmonella, especially in serovar Typhimurium, results from both gene transfers and strain dissemination.  (+info)

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Synonyms for R plasmid in Free Thesaurus. Antonyms for R plasmid. 1 synonym for plasmid: plasmid DNA. What are synonyms for R plasmid?
resistance plasmid definition: The definition of a resistance plasmid is a small element outside the chromosome that carries DNA information that fights against antibiotic drugs. (noun) An example of a resistance plasmid is pBR322 which carries the genes for tetr...
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Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger. ...
Nucleotide sequence of an OXA-2 beta-lactamase gene from the R-plasmid R1767 derived plasmid pBP11 and comparison to closely related resistance determinants found in R46 and ...
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Two clinical isolates of Pseudomonas aeruginosa, one a pyocin type 5 strain from Atlanta, could transfer gentamicin resistance by conjugation. Donor and recipient strains inactivated gentamicin by acetylation. The R plasmids, pMG1 and pMG2, also determined resistance to sisomicin, another substrate of gentamicin acetyltransferase I, sulfonamides, and streptomycin, but not resistance to kanamycin, neomycin, tobramycin, butirosin, or BB-K 8. They were transmissible to many strains of P. aeruginosa, including a Rec− strain, but not to Escherichia coli or other enterobacteriaceae. These R plasmids were compatible with R plasmids transmissible to P. aeruginosa from E. coli, including members of C, N, P, and W incompatibility groups. From a strain carrying pMG1 and a compatible plasmid, pMG1 was transferred independently but transfer of the second plasmid often resulted in cotransfer of pMG1. In contrast, pMG1 and pMG2 were incompatible with pseudomonas R plasmids R931 and R3108, and with R931 they ...
Promiscuous plasmids replicate in a wide range of bacteria and therefore play a key role in the dissemination of various host-beneficial traits, including antibiotic resistance. Despite the medical relevance, little is known about the evolutionary dynamics through which drug resistance plasmids adapt to new hosts and thereby persist in the absence of antibiotics. We previously showed that the incompatibility group P-1 (IncP-1) minireplicon pMS0506 drastically improved its stability in novel host Shewanella oneidensis MR-1 after 1,000 generations under antibiotic selection for the plasmid. The only mutations found were those affecting the N terminus of the plasmid replication initiation protein TrfA1. Our aim in this study was to gain insight into the dynamics of plasmid evolution. Changes in stability and genotype frequencies of pMS0506 were monitored in evolving populations of MR-1 (pMS0506). Genotypes were determined by sequencing trfA1 amplicons from individual clones and by 454 ...
SimPlot analysis.Similarity plots with plasmids R751, pBP136 and pB3 as reference plasmids. Each coloured plot corresponds to a specific plasmid depicted in the
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GENETIC BASIS OF RESISTANCE:. Most drug resistance is due to a genetic change in the organism, either as a chromosomal mutation or the acquisition of a plasmid ortransposon. a) CHROMOSOME-MEDIATED-RESISTANCE:. Chromosomal resistance is due to a mutation in the gene that codes for either the target of the drug or the transport system in the membrane that controls the uptake of the drug. The frequency of spontaneous mutations usually ranges from 10~ 7 to 10 ~ 9 which is much lower then the frequency of acquisition of resistance plasmids. Therefore, chromosomal resilience is less of a clinical problem than plasmid. Mediated resistance. b) PLASMID-MED1ATED RESISTANCE:. Plasmid-mediated resistance is very important from clinical point of view for 3 reasons: 1) It occurs in many different species, especially gram negative rods. 2) Plasmida frequently madiate resistance to multiple drugs. 3) Plasmids have a high rate of trans. for from one cell to another, usually by conjugation. Resistance plasmids ...
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InChI=1S/C25H44O2Si/c1-23(2,3)28(6,7)27-22-11-10-20-19-9-8-17-16-18(26)12-14-24(17,4)21(19)13-15-25(20,22)5/h17,19-22H,8-16H2,1- ...
InChI=1S/C30H58O4Si3/c1-28-17-14-23(33-36(6,7)8)20-22(28)12-13-24-25(28)15-18-29(2)26(24)16-19-30(29,34-37(9,10)11)27(31)21-32-35(3,4)5/h22-26H,12-21H2,1- ...
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1 ...
InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34) ...
InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26) ...
InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3 ...
InChI=1S/C65H104N18O26S4/c1-25(2)15-34-55(98)80-41-24-113-110-21-38(58(101)77-37(65(108)109)16-26(3)4)71-44(87)20-69-62(105)50(30(10)84)83-61(104)40(78-51(94)29(9)70-63(106)48(27(5)6)81-57(100)35(18-43(68)86)76-64(107)49(28(7)8)82-60(41)103)23-112-111-22-39(59(102)73-32(53(96)75-34)11-13-45(88)89)79-54(97)33(12-14-46(90)91)72-56(99)36(19-47(92)93)74-52(95)31(66)17-42(67)85/h25-41,48-50,84H,11-24,66H2,1-10H3,(H2,67,85)(H2,68,86)(H,69,105)(H,70,106)(H,71,87)(H,72,99)(H,73,102)(H,74,95)(H,75,96)(H,76,107)(H,77,101)(H,78,94)(H,79,97)(H,80,98)(H,81,100)(H,82,103)(H,83,104)(H,88,89)(H,90,91)(H,92,93)(H,108,109)/t29-,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,48-,49-,50-/m0/ ...
InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 ...
Definition of transferable resistance in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is transferable resistance? Meaning of transferable resistance as a finance term. What does transferable resistance mean in finance?
Although IncP-1 plasmids are important for horizontal gene transfer among bacteria, in particular antibiotic resistance spread, so far only three plasmids from the subgroup IncP-1 alpha have been completely sequenced. In this study we doubled this number. The three IncP-1 alpha plasmids pB5, pB11 and pSP21 were isolated from bacteria of two different sewage treatment plants and sequenced by a combination of next-generation and capillary sequencing technologies. A comparative analysis including the previously analysed IncP-1 alpha plasmids RK2, pTB11 and pBS228 revealed a highly conserved plasmid backbone (at least 99.9% DNA sequence identity) comprising 54 core genes. The accessory elements of the plasmid pB5 constitute a class 1 integron interrupting the parC gene and an IS6100 copy inserted into the integron. In addition, the tetracycline resistance genes tetAR and the ISTB11-like element are located between the klc operon and the trfA-ssb operon. Plasmid pB11 is loaded with a Tn5053-like ...
The molecular nature and replicative behavior of R factor 222 was examined in Proteus mirabilis . In deoxyribonucleic acid (DNA} from R+ P. mirabilis , R factor 222 was identified by CsCl density gradient centrifugation as 2 satellite DNA bands at densities corresponding to 50 and 58 moles percent guanine plus cytosine (% GC) . Replication of the 50 and 58% GC components of R factor 222 in P. mirabilis was analyzed during growth in the presence and absence of chloramphenicol (CAM} and after shifting exponentialand stationary- phase cells to conditions which inhibit host protein or DNA synthesis . CAM reduced the cellular growth rate but increased the amount of both R factor components relative to host chromosomal DNA . However, the 58% GC component showed a larger proportionate increase. This was inferred to indicate reduced synthesis of an inhibitor that acts on both R factor components and an initiator required for replication of the 50% GC component . Replicative patterns observed after shifting
SUMMARY: Transfer of RP4 and related replicons belonging to the Escherichia coli incompatibility group P (Pseudomonas aeruginosa IncP1) to races 2 and 6 of P. syringae pv. pisi was associated with the creation of two types of transconjugant, one resembling the parental race and the other showing an altered cultivar-specificity towards pea. The latter, irrespective of the parental race, exhibited a novel pattern of interaction with pea that corresponded to race 4; consequently such transconjugants were termed race 4-like. Curing of RP4 did not affect the phenotype, except in relation to the antibiotic resistances specified by RP4. The race 4-like strains were non-fluorescent when cultured on appropriate media (in contrast to the particular isolates of races 2 and 6 from which they were derived), showed an enhanced ability to inherit RP4 subsequently (at frequencies up to 10-1 per recipient) and differed from their parental race in their pattern of plasmid profile. The plasmid profiles were similar for
In the PBE lab we study the role of plasmids as catalysts of bacterial evolution, with a special focus on the evolution of plasmid-mediated antibiotic resistance.. Currently, we have two ongoing projects:. - In vivo evolution of plasmid-mediated resistance.. Conjugative plasmids play a key role in the horizontal spread of antibiotic resistance mechanisms among bacteria. One of the key factors undermining the successful spread of a conjugative plasmid is the initial fitness cost produced by the plasmid in the recipient bacteria. The factors involved in this cost and its potential compensation remain largely unknown. In our lab we are trying to understand the evolutionary and genetic determinants that promote the emergence and establishment of successful associations between bacterial clones and resistance plasmids in vivo.. To do so we study conjugation events between different enterobacteria occurring in the gut of hospitalized patients. We study the cost produced by the plasmids when they first ...
In the PBE lab we are interested in the evolutionary forces that drive plasmid dynamics in bacterial populations. Plasmids play a crucial role in bacterial ecology and evolution because they can transfer genes horizontally between different bacteria. The most striking example of how plasmids drive bacterial evolution is the global spread of plasmid-mediated antibiotic resistance over the last few decades. Plasmids are arguably the main vehicle for the spread of antibiotic resistance genes among clinically relevant bacteria, contributing to the overwhelming antibiotic resistance crisis we are currently facing.. In our group we try to understand the population genetics of antibiotic resistance plasmids using advanced molecular and evolutionary techniques. Ultimately, we intend to apply the concepts that we learn from the study of the evolution of plasmid-mediated antibiotic resistance to develop more rational intervention strategies to control infectious diseases.. ...
Individual bacterial cells may contain several different types of plasmids and in some cases more than 10 at a time. Plasmids are generally isolated from the bacterial cells in the supercoiled configuration. So far, thousands of different types of plasmids have been isolated. More than 300 different types of naturally occurring plasmids have been isolated from E.coli alone. Though, plasmids are not considered as part of the cells genome, when a bacterial cell divides each daughter cells receives a copy of each plasmid. Plasmids can also be transferred from one bacterial cell to another by the process called conjugation. Plasmids that govern their own transfer by conjugation are called conjugative plasmids but not all plasmids are conjugative.. ...
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After the development of antimicrobial agents in the 1940s, the notion was prevalent that these drugs would end infectious diseases caused by bacteria. Of course that did not happen, and the reason was the occurrence of antibiotic resistance. Investigations carried out primarily in laboratories in Japan and the United Kingdom in the early 1960s showed that antibiotic resistance in bacteria commonly is associated with the acquisition of genes-often multiple genes-capable of destroying antibiotics or otherwise interfering with their actions. The resistance properties commonly did not map genetically to the bacterial chromosomes, suggesting that the genes encoding resistance were located on separate elements (some had called them episomes) analogous to the fertility factor (F-factor) discovered earlier (12). Like F-factors, resistance factors (R-factors) were capable of being transferred between bacteria by cell-to-cell contact (13, 14). In 1952, Joshua Lederberg had given the name plasmids to ...
The combination of a p15A and a colE1 origin of replication plasmid is the most common two-plasmid system for use in E. coli. The pSB1A* series of plasmids contain the colE1 plasmid and cannot be co-maintained at stable copy numbers in combination due to plasmid incompatibility. Here, two plasmids in the same cell with origins from the same incompatibility group compete for replication machinery, resulting in unpredictable copy number and often the exclusion of one of the plasmids. This is circumvented by cotransforming plasmids with origins from distinct incompatibility groups. Since no p15A origin plasmid was present in the Registry, we developed part J23001, or pSB3C6 for our studies. This plasmid was used for all our riboregulator experiments for the locked-RFP reporter. Shown here is the variant of the plasmid containing part J01022. Plasmids for constructing basic Biobrick parts ...
Enterococcus faecalis is a bacterium found in the intestine of humans as well as in a wide variety of ecological niches. While it is not as virulent as Staphylo...
Dive into the research topics of Site- and strand-specific nicking at oriT of plasmid R100 in a purified system: Enhancement of the nicking activity of tral (helicase I) with traY and IHF. Together they form a unique fingerprint. ...
Plasmid R777-E258 Hs.RASSF3-nostop from Dr. Dominic Espositos lab contains the insert RASSF3. This plasmid is available through Addgene.
InChI:InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34) ...
InChI=1S/C22H22O12/c1-31-12-3-2-8(13-7-11(25)16-10(24)5-9(23)6-15(16)32-13)4-14(12)33-22-19(28)17(26)18(27)20(34-22)21(29)30/h2-6,13,17-20,22-24,26-28H,7H2,1H3,(H,29,30)/t13?,17?,18-,19+,20?,22+/m0/ ...
InChI=1S/C15H16O10/c16-7-5-6(2-4-9(17)18)1-3-8(7)24-15-12(21)10(19)11(20)13(25-15)14(22)23/h1-5,10-13,15-16,19-21H,(H,17,18)(H,22,23)/b4-2+/t10-,11-,12?,13?,15+/m0/ ...
After freezing and thawing, Pseudomonas aeruginosa harboring a drug resistance plasmid (Hg , Strep ), became acutely sensitive to mercuric ions but not to streptomycin in the plating medium. Its sensitivity to both agents in the plating medium became more pronounced, suggesting a synergistic effect of the mercuric ions with streptomycin. This freeze-thaw-induced sensitivity was transient and capable of being repaired in a simple salts medium (0.5%K2HPO4 + 0.04%MJSO4 pH7.7). Transient wall and membrane damage were also observed in frozen-thawed preparations. From kinetics studies, repair of membrane damage preceded repair of wall damage and damage measured by mercuric ions and mercuric ions plus streptomycin. Osmotically shocked cells also were sensitive to mercuric ions, mercuric ions plus streptomycin and sodium lauryl sulfate, but not to sodium chloride or streptomycin alone. This sensitivity was transient and capable of repair in the same simple salts medium. Active transport of a ...
SUMMARY. Trimethoprim-resistant urinary isolates of Escherichia coli, collected in 1982, were studied and the results compared with those obtained for isolates collected during the period 1979-1980. Ninety-eight (81%; a 10% increase) were resistant to trimethoprim 1024 μg/ml and 93 (95%) were also resistant to sulphamethoxazole 1024 μg/ml. The frequency distributions of plasmids were similar in both collections although there was a significant increase in the number of small plasmids (mol. wt ≤ 20 x 106) in the 1982 collection. Transfer of resistance was associated with isolates that carried larger numbers of plasmids. A significantly smaller proportion of isolates in this, than in the earlier series, transferred trimethoprim resistance to E. coli K12 suggesting continued transposition of trimethoprim resistance on to the bacterial chromosome. Fifteen different trimethoprim resistance plasmids were identified, of which five, including that found most frequently, were common to both collections.
Molecular Characterization of the R Factors Implicated in the Carbenicillin Resistance of a Sequence of Pseudomonas aeruginosa Strains Isolated from Burns: An o
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Plasmid psbA2-Ptrc-PHLS (d) from Dr. Anastasios Meliss lab contains the inserts beta-phellandrene synthase and Chloramphenicol resistance and is published in Planta May 2014 This plasmid is available through Addgene.
SB> As Ian Miller said, please send an email SB> to [email protected] regarding SB> this issue. You may get some useful SB> assistance. Why be so
Here is an example of Complete filtering based on a factor: The droplevels() function removes unused levels of factor variables from our dataset.
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InChI=1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1 ...
Other factors. There are also reasons why a placebo treatment group may outperform a "no-treatment" group in a test which are ... Social factors. Authors have speculated on the socio-cultural and psychological reasons for the appeal of alternative medicines ... The popularity of complementary & alternative medicine (CAM) may be related to other factors that Edzard Ernst mentioned in an ... This and other modern reviews suggest that other factors like natural recovery and reporting bias should also be considered.[ ...
Factors[edit]. The major controlling factor over a tropical monsoon climate is its relationship to the monsoon circulation. The ...
Systemic factors[edit]. Most common factors[edit]. *Infectious diseases (e.g. common cold) ... Other possible factors[edit]. This section does not cite any sources. Please help improve this section by adding citations to ... Local factors[edit]. *Blunt trauma (usually a sharp blow to the face such as a punch, sometimes accompanying a nasal fracture) ... Other possible factors[edit]. *Anatomical deformities (e.g. septal spurs or hereditary hemorrhagic telangiectasia) ...
Potential risk factors[edit]. Temperature and heat exposure[edit]. The temperature and heat levels of the body are directly ... This factor is particularly interesting due to the fact that a large population of people listen to music while exercising. ... Blockage of the ear canal, common in [headphones], is thought to be a main contributing factor in listener fatigue. When cut ... and P1 polymorphisms as susceptibility factors for noise-induced temporary threshold shift. [Article]. Hearing Research, 257(1- ...
Causes and Risk Factors[edit]. The cause of PNES has not yet been established. One hypothesis is that they are a learned ... The risk factors for FND can include trauma, illness exposure, symptom monitoring, and abnormal beliefs and expectations about ... McDade G, Brown SW (March 1992). "Non-epileptic seizures: management and predictive factors of outcome". Seizure. 1 (1): 7-10. ... easiest factor to distinguish), seizures having a gradual onset, a fluctuating course of disease severity, the eyes being ...
Freight rate factors[edit]. To the extent that price difference between WTI and Brent crude entice traders to ship WTI to North ... US supply factors[edit]. In February 2011, WTI was trading around $85/barrel while Brent was at $103/barrel. The reason most ... Brent crude production and trading factors[edit]. Premiums/discounts between WTI and Brent crude also reflects declining crude ...
Factors influencing display behaviour in animals[edit]. Display behaviour is a set of very conspicuous behaviours that allows ... Brooke, P. N.; Alford, R. A.; Schwarzkopf, L. (2000-12-04). "Environmental and social factors influence chorusing behaviour in ... Depending upon the species and evolutionary histories, environmental factors such as temperature, elevation, and precipitation ... The first factor is temporal. Depending on the time of the season, animals (more specifically, tropical frogs, in this study) ...
Risk factors[edit]. *Age, especially young children[8][9][11] *Primary dentition stage (2-3 years old, when children's motor ... Dental traumatic accidents depends on one's activity status and also the surrounding environment factor but these are the main ... Kania MJ, Keeling SD, McGorray SP, Wheeler TT, King GJ (1996). "Risk factors associated with incisor injury in elementary ... Granville-Garcia AF, de Menezes VA, de Lira PI (December 2006). "Dental trauma and associated factors in Brazilian preschoolers ...
Factor analysis[edit]. Researchers have reported that the JP and the SN scales correlate with one another.[35] One factor- ... Two-factor models of personality § Factors integrated into modern instruments (CPI 260) ... McCrae, R.R. (1992). Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) Manual. Odessa, FL: ... "University of Oregon: "Measuring the Big Five Personality Factors"". Retrieved 2008-08-08.. [self-published source?] ...
Factors[edit]. Moisture levels[edit]. Rain and humidity levels in the area where the body is found can affect the time for ...
Factors[edit]. Coagulation is affected by the type of coagulant used, its dose and mass; pH and initial turbidity of the water ...
The lupus anticoagulant will inhibit all the contact activation pathway factors (factor VIII, factor IX, factor XI and factor ... Risk factors[edit]. Risk factors for developing antiphospholipid syndrome include:[citation needed] ... Further studies for factor V Leiden variant and the prothrombin G20210A mutation, factor VIII levels, MTHFR mutation. ... Distinguishing a lupus antibody from a specific coagulation factor inhibitor (e.g.: factor VIII) is normally achieved by ...
F50-F59) Behavioural syndromes associated with physiological disturbances and physical factors[edit]. *(F50) Eating disorders * ... F59) Unspecified behavioural syndromes associated with physiological disturbances and physical factors. (F60-F69) Disorders of ... 1.6 (F50-F59) Behavioural syndromes associated with physiological disturbances and physical factors ... F54) Psychological and behavioural factors associated with disorders or diseases classified elsewhere ...
BDNF, brain-derived neurotrophic factor, ANON2, BULN2, Brain-derived neurotrophic factor, brain derived neurotrophic factor. ... Brain-derived neurotrophic factor (BDNF), or abrineurin,[5] is a protein[6] that, in humans, is encoded by the BDNF gene.[7][8] ... which are related to the canonical nerve growth factor. Neurotrophic factors are found in the brain and the periphery. BDNF was ... growth factor activity. • GO:0001948 protein binding. Cellular component. • cytoplasm. • perinuclear region of cytoplasm. • ...
... genetic factors and environmental factors are thought to be of roughly equal importance.[13] The genetic factors are better ... growth factors, neurotrophic factors, anti-inflammatory drugs, antioxidants, anti-apoptotic drugs, and drugs to improve ... Environmental factors[edit]. Where no family history of the disease is present - around 90% of cases - no cause is known. ... The cause is not known in 90% to 95% of cases,[4] but is believed to involve both genetic and environmental factors.[13] The ...
Form factors[edit]. Main article: List of hard disk drive form factors ... The factors that limit the time to access the data on an HDD are mostly related to the mechanical nature of the rotating disks ... Drives with non-removable eight-inch platters appeared, and then drives that used a 5 1⁄4 in (130 mm) form factor (a mounting ... This became a standard platter size and drive form-factor for many years, used also by other manufacturers.[103] The IBM 2314 ...
... therefore the cost of transporting is a crucial factor here. Other factors might be legal controls which restricts an ... Other Related Factors[edit]. According to the Guidance, there are three more issues that must be examined. They are actual ... The two primary factors determining monopoly market power are the company's demand curve and its cost structure.[37] ... The first thing to consider is market definition which is one of the crucial factors of the test.[72] It includes relevant ...
TNF, DIF, TNF-alpha, TNFA, TNFSF2, Tumour necrosis factor, TNF-α, tumor necrosis factor, TNLG1F, Tumor necrosis factor alpha. ... Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) ... reported another cytotoxic factor produced by macrophages and named it tumor necrosis factor (TNF).[14] Both factors were ... "Identity of tumour necrosis factor and the macrophage-secreted factor cachectin". Nature. 316 (6028): 552-4. Bibcode:1985Natur. ...
U-factor/U-value[edit]. See also: Thermal transmittance. The U-factor or U-value is the overall heat transfer coefficient that ... Factors[edit]. There are many factors that come into play when using R-values to compute heat loss for a particular wall. ... The usual standard is at a temperature gradient of 24 °C (75.2 °F), at 50% humidity with no wind[24] (a smaller U-factor is ... Note that the term "U-factor" (which redirects here) is usually used in the U.S. and Canada to express the heat flow through ...
... a neurotrophic factor important for long-term memory.[66] Expression of CREB, an activity-dependent transcription factor ... Several genetic factors have been identified as contributing to AD, including mutations to the amyloid precursor protein (APP) ... Epigenetic factors[edit]. ncRNA. Reductions of miR-133b correlated to decreased numbers of dopaminergic neurons in the midbrain ... factors have not consistently been shown to play a role in progression of AD. miRNAs are involved in post-transcriptional gene ...
Risk factors. No quieren (They do not want to) by Francisco Goya (1746-1828) depicts an elderly woman wielding a knife in ... part II: investigating factor structure findings in a national clinic-referred youth sample". Journal of Traumatic Stress. 26 ( ... Brain catecholamine levels are high,[88] and corticotropin-releasing factor (CRF) concentrations are high.[89][90] Together, ... Military service is a risk factor for developing PTSD.[56] Around 78% of people exposed to combat do not develop PTSD; in about ...
Contributing factors and research outcomes. Main article: Well-being contributing factors. Research on positive psychology, ... "In Buddhism, There Are Seven Factors of Enlightenment. What Are They?". Religion & Spirituality. Archived from the ... When basic needs are satisfied, the degree of happiness depends on economic and cultural factors that enable free choice in how ... Some usages can include both of these factors. Subjective well-being[20] includes measures of current experience (emotions, ...
Success or failure factors[edit]. One of the areas in which sperm injection can be useful is vasectomy reversal. However, ... Correction factors have been developed and should be used when screening for Down syndrome in singleton pregnancies after ICSI, ... potential factors that may influence pregnancy rates (and live birth rates) in ICSI include level of DNA fragmentation[29] as ... 33] but in twin pregnancies such correction factors have not been fully elucidated.[33] In vanishing twin pregnancies with a ...
I added the lack of ILS, I did not state that it was not a factor. It is clearly a factor, I don't know why someone felt the ... That "cultural factor" has been researched and discussed in many "Human Factors" tomes on airline safety. KAL pilots used to ... We do not know what factors led to the accident, and we do not know the extent to which any particular characteristics of the ... Has the NTSB ruled out the lack of ILS being a factor? If so, there should be a citation. If not, the claim should be removed ...
Factors leading to pedal misapplication[edit]. On March 10, 2010, The New York Times ran a piece by Richard Schmidt, PhD, ... All factors point to reduced driver familiarity and sophistication. On March 12, 2010, Autoline Detroit argued that searches ... "IEEE Spectrum Risk Factor Blog. Archived from the original on 2010-02-11. Retrieved 2010-01-30.. ... namely elderly drivers and pedal misapplication as factors.[226] Also noted was that drivers with Type II diabetes (adult onset ...
"X Factor Starlet Cher Lloyd to Fight on". Daily Star.. *^ "Recap - 'The X Factor': Judges' Houses - X Factor News - TV" ... After the finale of the seventh series of The X Factor, it was announced that Lloyd had been signed to Syco Music.[17] Shortly ... "The X Factor 2010: the 12 acts who made it to the Live Shows". STV Entertainment. 3 October 2010. Retrieved 23 August 2011.. ... "Cher Lloyd: 'X Factor UK' at 16, Engaged at 18, and Still Never Growing Up (In House)". Blogmusic. Retrieved 22 May 2012.. ...
Power factor[edit]. See also: Power factor. A problem in the combination of a double-conversion UPS and a generator is the ... Passive power-factor correction[edit]. Main article: Passive PFC. Classic solutions such as passive filters reduce THDI to 5%- ... Active power-factor correction[edit]. Main article: Active PFC. An alternative solution is an active filter. Through the use of ... Form factors[edit]. UPS systems come in several different forms and sizes. However, the two most common forms are tower and ...
Critical factors for function[edit]. Calcium. Calcium dynamics are essential for several functions of granule cells such as ...
is a friction factor, and τ. ∗. {\displaystyle \tau *}. is the Shields stress. The Engelund-Hansen formula is one of the few ... through the generalized Darcy-Weisbach friction factor, C. f. {\displaystyle C_{f}}. , which is equal to the Darcy-Weisbach ... Shear velocity, velocity, and friction factor[edit]. For the steady case, by extrapolating the depth-slope product and the ... friction factor divided by 8 (for mathematical convenience).[13] Inserting this friction factor, ...
... tumor necrosis factor β (TNF-β), transforming growth factor α (TGF-α),[67] transforming growth factor β (TGF-β),[68] heregulin, ... 69] Wnt,[40] RANKL,[40] and leukemia inhibitory factor (LIF).[40] These factors regulate cellular growth, proliferation, and ... insulin-like growth factor 1 (IGF-1), and prolactin.[1] These regulators induce the expression of growth factors, such as ... insulin-like growth factor binding protein-3 and epidermal growth factor on human breast epithelial cells in primary culture". ...
Risk factors are those characteristics associated with child maltreatment and abuse, they may or may not be direct causes. ... Protective Factors for Child Abuse and Neglect. Protective factors may lessen the likelihood of children being abused or ... Risk Factors for Victimization. Individual Risk Factors. *Children younger than 4 years of age ... Risk Factors for Perpetration. Individual Risk Factors. *Caregivers with drug or alcohol issues ...
The Behavioral Risk Factor Surveillance System (BRFSS) is the nations premier system of health-related telephone surveys that ...
Migration-stimulating factor (MSF). *Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein ... Growth factors are important for regulating a variety of cellular processes. Growth factors typically act as signaling ... For example, epidermal growth factor (EGF) enhances osteogenic differentiation, [2] while fibroblast growth factors and ... "growth factor" at Dorlands Medical Dictionary *^ Del Angel-Mosqueda C, Gutiérrez-Puente Y, López-Lozano AP, Romero-Zavaleta RE ...
Vaccination with irradiated granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting gene-transduced cancer vaccines ... macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and ... CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental ... Antitumor effect induced by granulocyte/macrophage-colony-stimulating factor gene-modified tumor vaccination: comparison of ...
BOYD, W., LATTER, J. & ROBSON, W. Growth Factors. Nature 127, 308 (1931). ...
The CNTF family of neurotrophic factors includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), ... Nerve growth factor[edit]. Nerve growth factor (NGF) uses the high-affinity receptor TrkA[11][8] to promote myelination[11] and ... glia maturation factor, insulin, insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), fibroblast ... Brain-derived neurotrophic factor[edit]. Brain-derived neurotrophic factor (BDNF) is structurally similar to NGF, NT-3, and NT- ...
Factors influencingFactors influencing creativity andcreativity and innovation--- creativityinnovation--- creativity Prince ... 3. Factors influencing creativity • Factors • Individual level • Group and organisational level Category of factors Factors ( ... 4. Factors affecting creativity Category Factors (Amabile et al 1996) Organisational encouragement Encouraging of risk taking ... Factors influencing creativity * 1. Factors influencingFactors influencing creativity andcreativity and innovation--- ...
... Aims and Intentions. Labelling rules require that where ingredients are highlighted in the name ... The Sub-committee oversees the determination of nitrogen factors for meat, poultry and seafood for use by both enforcement ... The Subcommittee has already produced reports on nitrogen factors for pork (1991), beef (1993), mutton and lamb (1995, 1996), ... and converts this to a meat or fish content using a previously determined nitrogen factor. ...
Factors of production is an economic term to describe the inputs that are used in the production of goods or services in an ... What Are Factors of Production? Factors of production is an economic term that describes the inputs used in the production of ... The Basics of Factors of Production The modern definition of factors of production is primarily derived from a neoclassical ... Ownership of Factors of Production The definition of factors of production in economic systems presumes that ownership lies ...
Risk Factors for Type 2 Violence Unit 4: Risk Factors for Type 3 Violence Unit 5: Prevention Strategies for Organizations Unit ... Unit 4: Risk Factors for Type 3 Violence Workplace Violence Prevention for Nurses About This Course Unit 1: Definitions, Types ... Contributing Factors. The Joint Commission has acknowledged that "intimidating and disruptive behaviors" among co-workers in ... "Systemic factors stem from the unique health care cultural environment, which is marked by pressures that include increased ...
... 370136. MANY comprehensive papers have been presented on the various phases of the cooling ... Citation: Winkler, H., "Engine-Temperature Control Factors," SAE Technical Paper 370136, 1937, ...
Human Factors in Risk Assessment. When we address human factors in relation to health and safety, were aiming to optimise ... The approach you take to human factors in risk assessment should be proportionate to hazards you face. For most industries a ... More information on Human Factors in Risk Assessment. *Reducing error and influencing behaviour (HSG48), HSE Books 1999, ISBN 0 ... The people carrying out the assessment should have an understanding of the different types of failure and the factors that make ...
... also called an uncertainty factor or assessment factor) is a number by which some variable such as load or dose is multiplied ... Safety factors are used in engineering design, toxicology, and other disciplines to avoid various types of failure. Source for ... information on Safety Factors: Encyclopedia of Science, Technology, and Ethics dictionary. ... To… Factor Viii , Factor VIII (antihaemophilic factor) One of the blood clotting factors. Factor VIII is a soluble protein that ...
... factor VIII and factor X play a role in blood clotting. Lab tests can measure clotting factors to help diagnose the cause of ... While von Willebrand factor may be ordered along with coagulation factors if an inherited factor deficiency is suspected, it is ... as well as which factor is deficient. Those who have a severely deficient factor or one with significant factor dysfunction ... For example, coagulation factor II is also known as prothrombin. When one or more of these factors are produced in too small a ...
... is a short-term solution; most companies factor for two years or less. Plant says the factors role is to help ... Still, plenty of misperceptions about factoring remain.. Factoring is not a loan; it does not create a liability on the balance ... One of the oldest forms of business financing, factoring is the cash-management tool of choice for many companies. Factoring is ... Yes, when you compare the discount rate factors charge against the interest rate banks charge, factoring costs more. But if you ...
Factor Bikes - Life After The World Tour - Duration: 2 minutes, 51 seconds.. Factor Bikes ... The Factor O2 is our beautiful chameleon - our most versatile bikes that combines minimalist beauty with exceptional ...
Source for information on Health, Social Factors: Encyclopedia of Aging dictionary. ... SOCIAL FACTORS To understand the connection between social factors and health, it is necessary to examine the average level of ... HEALTH, SOCIAL FACTORS. To understand the connection between social factors and health, it is necessary to examine the average ... Rather, factors associated with being widowed and not remarrying appear to cause poorer health. However, the relationship ...
Risk Factors for Type 2 Violence Unit 4: Risk Factors for Type 3 Violence Unit 5: Prevention Strategies for Organizations Unit ... Unit 3: Risk Factors for Type 2 Violence Workplace Violence Prevention for Nurses About This Course Unit 1: Definitions, Types ... Clinical Risk Factors. The clinical setting is one of intensified emotions. Patients who are at risk of perpetrating violence ...
Human factors: Learning organisations. A learning organisation not only values and encourages learning from its own experiences ...
We will therefore limit ourselves to studying the factors.. Direct and indirect factors. The factors are either direct -in the ... We must also identify the deforestation factor: it is locally known, and its relative extent in relation to other factors can ... The underlying causes are the triggering mechanisms for these factors. In the case of the first factor, we might say that the ... Should one attribute deforestation to the direct factor, to the indirect factor, or to both? In our view, we must always ...
Check out latest impact factors for Springer journals in your discipline and find more details, such as: how to submit, new ... Announcement of the latest impact factors from the Journal Citation Reports. Researchers consider a number of factors in ... We invite you to explore our latest journal metrics, including the newly released 2019 impact factors, and to read some of the ...
Check out latest impact factors for Springer journals in your discipline and find more details, such as: how to submit, new ... Announcement of the latest impact factors from the Journal Citation Reports. Researchers consider a number of factors in ... We invite you to explore our latest journal metrics, including the newly released 2019 impact factors, and to read some of the ... Journals receiving their first impact factor: Bio-Design and Manufacturing , Geomechanics and Geophysics for Geo-Energy and Geo ...
Factors That Affect SolubilityChemistrySolutionsWhat Are Solutions?How and Why Do Things Dissolve?Determining the Concentration ... Though pressure is an important factor in the solubility of a gas, pressure has very little effect on the solubilities of ...
Bookwire offers the most complete list of books on factors with comparison prices of the books you want from all the major ... How to Boost Your L Factor and Achieve Your... Author: Sanders, Tim ISBN: 978-1-4000-8049-6 Book Format: Hardback. List Price: ... Hepatocyte Growth Factor - Scatter Factor (HGF-SF) and the C-Met Receptor ... Hepatocyte Growth Factor - Scatter Factor (HGF-SF) and the C-Met Receptor ...
For the same agent, a different discounting factor has to be used for every separate valuation occasion. If, however, one is ... and therefore accepts the concept of a stochastic discount factor, then an economically consistent theory can be developed. ... For the same agent, a different discounting factor has to be used for every separate valuation occasion. If, however, one is ... and therefore accepts the concept of a stochastic discount factor, then an economically consistent theory can be developed. ...
They are both on the up-regulation pathway for the gene for inflammation, tumor necrosis factor-α and nuclear factor KB. ... At present, it is believed that both genetic susceptibility and environmental factors are important in the development of ... Psoriasis Genetic Factors. News-Medical. 23 January 2020. , ... Psoriasis Genetic Factors. News-Medical, viewed 23 January 2020, ...
The strongest factor, which remained after the researchers adjusted for the racial makeup of the neighborhoods, was social ... While the role of economic and environmental factors in childhood asthma have been studied extensively, there has been very ... "Although one can understand how these factors may lead to increased interaction, they may also signify crowding and poverty," ... little investigation of how social factors might influence the prevalence of the disease, Gupta and her associates note in the ...
... and 27 percent versus 18 percent smoked.The researchers found that each of the three factors was linked to an increased risk of ... do not show whether those lifestyle factors may raise teenagers risk of developing frequent headaches in the first place.But ... is an important step in clarifying the effects of lifestyle factors on headache, according to the authors of an editorial ... have some of them reaching for cigarettes.Zwarts team agrees that mental health and other factors, like families ...
Human Factors in Simulation and Training. Peter A. Hancock,Dennis A. Vincenzi,John A. Wise,Mustapha Mouloua. Limited preview - ... gb-gplus-shareHuman Factors Aspects of Simulation. ... Human Factors Aspects of Simulation. Edward R. Jones, Robert T ... ... 0 Reviews ...
  • We invite you to explore our latest journal metrics , including the newly released 2019 impact factors, and to read some of the most influential articles in your field. (
  • Cite this: Penile Cancer Epidemiology and Risk Factors - Medscape - Mar 01, 2019. (
  • FEMA published a final rule on March 21, 2019, amending 44 C.F.R. 206.48(b) ( Factors considered when evaluating a Governor's request for a major disaster declaration ) which revised the factors that FEMA considers when evaluating a Governor's request for a major disaster declaration authorizing Individual Assistance. (
  • We're happy to announce that 111 De Gruyter journals received an 2018 Journal Impact Factor (Journal Citation Reports, Web of Science Group, 2019) this year, with 67 of them improving their ratings. (
  • For example, epidermal growth factor (EGF) enhances osteogenic differentiation, [2] while fibroblast growth factors and vascular endothelial growth factors stimulate blood vessel differentiation ( angiogenesis ). (
  • Ruggeri B.A., Klurfeld D.M., Kritchevsky D., and Furlanetto R.W. Caloric restriction and 7,12dimethylbenz(a)anthracene-induced mammary tumor growth in rats: alterations in circulating insulin, insulin-like growth factors I and II, and epidermal growth factor. (
  • In particular, the q-factor model fully subsumes the Fama-French (2018) 6-factor model in head-to-head factor spanning tests. (
  • Trust has really started to evolve as a search engine ranking factor, or set of factors. (
  • The search strategy for this paper included searching PubMed, Medline, and EMBASE databases for known risk factors. (
  • Only English language papers were included in the search, and the searches were limited to studies of risk factors influencing TB infection and disease. (
  • The researchers performed a systematic search to find previously published systematic reviews and meta-analyses that had assessed the associations between these risk factors and Alzheimer's disease or dementia. (
  • At present, it is believed that both genetic susceptibility and environmental factors are important in the development of psoriasis. (
  • A variety of external factors interacting with genetic susceptibility influence the carcinogenesis process. (
  • Although the main causes of lung cancer stems from environmental factors, the evidence for genetic susceptibility to lung cancer is compelling as genome-wide association studies have shown several regions associated with cancer risk and accumulation of familial cases have been observed in clinical studies. (
  • Socioeconomic and behavioral factors are also shown to increase the susceptibility to infection. (
  • If each of the four combinations of levels has replicate observations, then a cross-factored analysis can test for an interaction between the two treatment factors in their effect on the response. (
  • Such a strong weekly upward move is rare in the fall, but is explained by a confluence of factors, including oil prices hitting a new 2017 high, a major pipeline leak resulting in disruption, autumn refinery maintenance, but perhaps among the more surprising - robust demand for gasoline so late in the season. (
  • DUBAI, Jan 6 (Reuters) - Here are some factors that may affect Middle East stock markets on Sunday. (
  • DUBAI, Oct 1 (Reuters) - Here are some factors that may affect Middle East stock markets on Sunday. (
  • The analysis determines the nitrogen (mainly on a fat free basis) of meat or fish ingredient, and converts this to a meat or fish content using a previously determined nitrogen factor. (
  • Part 2 took an updated look at on-page SEO factors, including content, HTML and architecture. (
  • Incidence of and risk factors for falls and injurious falls among the community-dwelling elderly. (
  • Armstrong B. and Doll R. Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. (
  • However, there are many other risk factors associated with increased lung cancer incidence. (
  • Environmental factors such as diet have long been suspected of contributing to the high incidence of cardiovascular disease in Western societies. (
  • However, the study's estimates of incidence and risk factors that were used to derive this figure are based on global and US rates of risk factors that may not be specifically attributable to a UK population. (
  • While the role of economic and environmental factors in childhood asthma have been studied extensively, there has been very little investigation of how social factors might influence the prevalence of the disease, Gupta and her associates note in the Journal of Allergy and Clinical Immunology. (
  • However at the population level impact of this risk factor could vary depending on the local prevalence of the HIV. (
  • They decided not to look at diet owing to the variability in dietary factors studied and the absence of data on prevalence of dietary habits. (
  • Individual growth factor proteins tend to occur as members of larger families of structurally and evolutionarily related proteins. (
  • Neurotrophic factors ( NTFs ) are a family of biomolecules - nearly all of which are peptides or small proteins - that support the growth, survival, and differentiation of both developing and mature neurons. (
  • Coagulation factors are proteins circulating in the blood that are essential for proper blood clot formation. (
  • Coagulation factor tests measure the function of or sometimes the amount of these proteins in the blood. (
  • Restriction factors are anti-viral proteins that are produced in the host and counteract or 'restrict' viral replication. (
  • These factors include polysaccharide capsules and M proteins that impede phagocytosis, enzymes that degrade host tissues, and toxins that overstimulate the immune system, causing fever and shock. (
  • Walt Plant, regional manager with Altres Financial, a national factoring firm based in Salt Lake City, says the opposite is true: "Most of the businesses we deal with are very much in an upward cycle, going through extremely rapid growth. (
  • Research suggests that other factors such as smoking, being exposed to chemicals that can cause cancer, and changes in other hormones due to night shift working also may increase breast cancer risk. (
  • Parent involvement, student behavior, teacher collaboration, and professional development aren't the most important factors contributing to student achievement, suggests a survey of schools serving low-income students in California. (
  • These dietary factors tend to decrease 1,25(OH) 2 vitamin D, a cell differentiator, and low levels of this hormone may enhance prostate carcinogenesis. (
  • Growth factors" redirects here. (
  • For the journal, see Growth Factors (journal) . (
  • Growth factors are important for regulating a variety of cellular processes. (
  • Growth factors typically act as signaling molecules between cells. (
  • They often promote cell differentiation and maturation, which varies between growth factors. (
  • While some cytokines can be growth factors, such as G-CSF and GM-CSF , others have an inhibitory effect on cell growth or proliferation. (
  • The alpha granules in blood platelets contain growth factors PDGF, IGF-1, EGF, and TGF-β which begin healing of wounds by attracting and activating macrophages , fibroblasts , and endothelial cells . (
  • Higher safety factors such as 1,000, 2,000, and even 5,000 can be used in the regulation of substances believed to induce severe toxic effects in humans. (
  • If the car is expected to depreciate in value by $5,000 annually, this amount will be factored into the monthly payments. (
  • Different cancers have different risk factors. (
  • While doctors have an idea of what may increase your risk of cancer, the majority of cancers occur in people who don't have any known risk factors. (
  • Virulence factors of Francisella tularensis. (
  • produce a variety of so-called virulence factors that permit them to evade the defense mechanisms of the host and thus cause disease. (
  • Most cases of Alzheimer's disease-type dementia result from a mix of genetic, environmental and lifestyle factors. (
  • The estimate is based on a large, well-conducted review that looked at how seven lifestyle-related risk factors relate to the risk of Alzheimer's disease. (
  • The review determined how strongly the risk factors, which included obesity and smoking, were associated with Alzheimer's disease and the proportion of people worldwide and in the US whose condition could be attributed to these factors. (
  • The study found that approximately half of all cases of Alzheimer's disease were associated with one or more of the risk factors - diabetes, midlife high blood pressure, midlife obesity, depression, physical inactivity, smoking and low education. (
  • Although this important research updates knowledge on potential risk factors for Alzheimer's disease, it should be stressed that associations between these lifestyle factors and Alzheimer's does not mean that they cause the disease. (
  • This was a systematic review that investigated how seven potentially modifiable risk factors affected the risk of developing Alzheimer's disease. (
  • It should be noted that in this case the term 'risk' does not necessarily mean that a factor causes Alzheimer's disease - it relates to the chance of people in different groups having Alzheimer's disease. (
  • The researchers wanted to provide an updated summary of several modifiable risk factors for Alzheimer's disease. (
  • They also wanted to estimate how reducing the number of people with each risk factor would affect the number of people who go on to have Alzheimer's disease. (
  • They looked for systematic reviews and meta-analyses, written in English and published between 2005 and 2011, which had examined the associations between these risk factors and Alzheimer's disease or dementia. (
  • [8] Other experiments suggest BDNF is more important and necessary for neuronal survival than other factors. (
  • It is important to distinguish personal and private capital in factors of production. (
  • FAO forest assessments of 1980 to 2000 tried to determine the relative importance of direct deforestation factors at regional and global levels: horizontal expansion of the various forms of agriculture and animal husbandry taken together remains by far the most important direct factor, but the share of shifting cultivation as well as that of ranching and colonization programmes decreased during that period. (
  • It is important at the outset to carefully distinguish between the underlying causes of deforestation and forest degradation, about which there might be divergent views, and the actual factors, which could be part of the area of objective observation. (
  • Though pressure is an important factor in the solubility of a gas, pressure has very little effect on the solubilities of liquids or solids. (
  • The study "is an important step in clarifying the effects of lifestyle factors on headache," according to the authors of an editorial published with the report. (
  • In addition, various hormonal factors which influence growth and differentiation are critically important in the carcinogenic process. (
  • Understanding and being realistic about your risk factors for melanoma is an important step in prevention. (
  • A money factor may also be presented as a factor of 1,000, such as 2.0 rather than .002. (
  • Zwart's team agrees that mental health and other factors, like families' socioeconomic status, may help explain the relationships among smoking, weight, exercise and recurrent headaches. (
  • When we address human factors in relation to health and safety, we're aiming to optimise human performance and reduce human failures. (
  • Organisations need to take a proportionate approach to human factors in risk assessment based on their hazard and risk profile. (
  • The approach you take to human factors in risk assessment should be proportionate to hazards you face. (
  • An example of a qualitative framework that has been found to be useful and effective is the approach outlined in Core Topic 3 of Human Factors Inspectors Toolkit (pdf). (
  • In the Human Factors: Definition video, we review the definition of Human Factors and how it applies to what we do on a day-to-day basis. (
  • This video highlights what was previously discussed in the last Human Factors session, including human performance on the job, as well as stress and workload. (
  • A growth factor is a naturally occurring substance capable of stimulating cellular growth , [1] proliferation, healing, and cellular differentiation . (
  • Structural safety factors have been calculated for mammalian bones, crab claws, shells of limpets, and tree stems. (
  • Retrieved on January 23, 2020 from (
  • The long held belief that adults who are unable to quit smoking is ultimately related to duration of smoking may potentially be replaced by such research showing that there are specific genetic factors which could influence teen smokers to become heavy smokers throughout their lives. (
  • Genetic factors in ovarian carcinoma. (
  • They are both on the up-regulation pathway for the gene for inflammation, tumor necrosis factor-α and nuclear factor KB. (
  • Healthcare providers can help cut down a person's risk by reducing the fall risk factors listed above. (
  • The causes of late-onset Alzheimer's are not yet completely understood, but they likely include a combination of genetic, environmental, and lifestyle factors that affect a person's risk for developing the disease. (
  • The Subcommittee has already produced reports on nitrogen factors for pork (1991), beef (1993), mutton and lamb (1995, 1996), chicken (2000), scampi (2000), turkey (2002) and cod fillet and mince blocks for coated fish products (2007). (
  • Such factors as the number of miles you drive annually and your accident and ticket history are major elements in setting your insurance rate. (
  • Brain-derived neurotrophic factor (BDNF) is structurally similar to NGF, NT-3, and NT-4 /5, [7] and shares the TrkB receptor with NT-4. (
  • Overweight teens were 40 percent more likely to have recurrent headaches than their peers with none of the three negative lifestyle factors. (
  • Moreover, teenagers with all three unhealthy lifestyle factors showed the highest risk of recurrent headaches. (
  • The findings leave open the question of whether excess pounds, smoking or inactivity are risk factors for recurrent headaches, or whether they may exacerbate existing headaches -- making them more frequent or intense, according to Hershey and Lipton. (
  • In energy monitoring and targeting, a driving factor is something recurrent and measurable whose variation explains variation in energy consumption. (
  • A safety factor (also called an uncertainty factor or assessment factor) is a number by which some variable such as load or dose is multiplied or divided in order to increase safety. (
  • The sources of failure that safety factors are intended to protect against can be divided into two major categories: (a) the variability of conditions that influence the risk of failure, such as variations in the strength of steel and in the sensitivity of humans to toxic substances, and (b) the uncertainty of human knowledge, including the possibility that the models used for risk assessment may be inaccurate. (
  • 1983). "Regulatory History and Experimental Support of Uncertainty (Safety) Factors. (
  • The modern definition of factors of production is primarily derived from a neoclassical view of economics. (
  • It amalgamates past approaches to economic theory, such as the concept of labor as a factor of production from socialism, into a single definition. (
  • Land has a broad definition as a factor of production and can take on various forms, from agricultural land to commercial real estate to the resources available from a particular piece of land. (
  • The risk of infection following TB exposure is primarily governed by exogenous factors and is determined by an intrinsic combination of the infectiousness of the source case, proximity to contact and social and behavioural risk factors including smoking, alcohol, and indoor air pollution. (
  • There are two distinct factors: Extrinsic factor, much more commonly known as vitamin B12 Intrinsic factor, a glycoprotein produced by the parietal cells of the stomach, which is necessary for the absorption of vitamin B12 This disambiguation page lists articles associated with the title Castle factors. (
  • Systemic factors stem from the unique health care cultural environment, which is marked by pressures that include increased productivity demands, cost containment requirements, embedded hierarchies, and fear of or stress from litigation. (
  • To understand the connection between social factors and health, it is necessary to examine the average level of health of aging people in one social group and then compare this to the average level of health of those in another social group. (
  • Alternately, if being in a particular social position or group has an effect on one's health, researchers say that something about the social environment associated with that position or group has an effect on health, and they then must investigate further to determine the underlying factors. (
  • Various social factors may have an effect on health and health outcomes. (
  • For the study, Zwart's team interviewed 5,847 teenagers about a number of health and lifestyle factors, including any headaches they'd suffered in the past year not related to a cold or other acute illness. (
  • A risk factor is something that increases your chance of getting a disease or health problem. (
  • This paper summarizes these factors along with health system issues such as the effects of delay in diagnosis of TB in the transmission of the bacilli. (
  • Similarly, conditions which prolong the length of exposure to an infectious patient include health system-related factor such as delay in diagnosis. (
  • Prevention programmes will need to take into account the variety of health determinants and the interplay between all the different risk factors. (
  • Although more information is being discovered about neurotrophic factors, their classification is based on different cellular mechanisms and they are grouped into three main families: the neurotrophins , the CNTF family, and GDNF family . (
  • Castle (gastric) factors, named after the American physician and physiologist W. B. Castle, are biologically active chemical compounds which stimulate haematopoiesis (formation of blood cellular components). (
  • If you have breast cancer risk factors, talk with your doctor about ways you can lower your risk and about screening for breast cancer. (
  • Systematic reviews on risk factors tend to report their findings in terms of ' relative risks ', which express the risk of a disease in people with a risk factor relative to people without this risk factor (e.g. smokers vs. non-smokers). (
  • Identify the human failures that could be made in the task which might lead to an accident of incident and the performance influencing factors that make those failures more or less likely to occur. (
  • In order to be an efficient guide for safe design, safety factors should be applied to all the integrity-threatening mechanisms that can occur. (
  • The q-factor model shows strong explanatory power and largely summarizes the cross section of average stock returns. (
  • Factoring is very common in certain industries, such as the clothing industry, where long receivables are part of the business cycle. (
  • The money factor can be translated into the more common annual percentage rate (APR) by multiplying the money factor by 2,400. (
  • While the decimal version is more common, a money factor that is a whole number can still be converted to an APR by multiplying it by 2.4. (
  • The most common risk factor for melanoma is exposure to UV light from the sun or indoor tanning beds or booths. (
  • An overview of some of the most common fertility concerns or "factors" are listed below. (
  • In this paper we study factor models for security returns on financial markets, where some pervasive factors are common across all securities and other pervasive factors prevail only within some groups of securities but not in others. (
  • The clustering structure provides a natural way to group the securities and to interpret common factors and group-specific factors. (
  • We give conditions under which the common factor space and the group-specific factor spaces can be identified, and propose an effective procedure to estimate the unobservable structure in the factor space. (
  • Concretely, the procedure will determine the unknown number of groups, endogenously classify securities into groups, determine the number of common factors across all groups as well as the number of group-specific factors in each group, and estimate the common factors and the group-specific factors. (
  • Common Factors and Specific Factors ," MPRA Paper 36085, University Library of Munich, Germany. (
  • Common risk factors in the returns on stocks and bonds ," Journal of Financial Economics , Elsevier, vol. 33(1), pages 3-56, February. (
  • Excessive rapid weight gain and pregnancy are the two most common risk factors. (
  • One of the most common driving factors is the weather, expressed usually as heating or cooling degree days. (
  • What these examples all have in common is that on a weekly basis (say) numerical values can be recorded for each factor and one would expect particular streams of energy consumption to correlate with them either singly or in a multivariate model. (
  • As a factor of production, capital refers to the purchase of goods made with money in production. (
  • Peritoneal factor infertility refers to abnormalities involving the peritoneum (the membrane that lines the inside of your abdomen) such as scar tissues (adhesions) or endometriosis. (
  • An interaction between factors refers to the influence of one factor on a response depending on the level of another factor. (
  • The main factors that influence your risk include being a woman and getting older. (
  • The factors that affect gas exchange in humans include the amount of gases in the atmosphere. (
  • Other factors include society's influence. (
  • Other risk factors include the conditions described above that predispose the skin to developing stretch marks. (
  • However, knowledge in this area is still lacking because environmental factors often cover or confuse results in familial lung cancer studies. (
  • Environmental factors can also raise your risk of addiction. (
  • Most neurotrophic factors belong to one of three families: (1) neurotrophins , (2) glial cell-line derived neurotrophic factor family ligands (GFLs), and (3) neuropoietic cytokines. (
  • This article discusses the risk factors for stroke and things you can do to lessen your risk. (
  • The effect of a safety factor on the actual risk depends on the dose-response relationship. (
  • While the conversion factor of 2,400 stays the same, the money factor depends on the lessee's credit history. (
  • Treatment success depends on many factors, especially the age of the female partner. (
  • [2] Neurotrophic factors also promote the initial growth and development of neurons in the central nervous system and peripheral nervous system , and they are capable of regrowing damaged neurons in test tubes and animal models. (
  • We empirically test this caricature in the context of sequences of parole decisions made by experienced judges (mean experience = 22.5 y, SD = 2.5) and, in so doing, demonstrate how extraneous factors can sway highly consequential decisions of expert decision makers. (
  • The present work is aimed at investigating the tribological factors influencing the LDH test. (
  • For example, in a test of influences on crop yield, a watering regime factor (W: wet and dry) is crossed with a sowing density factor (D: high and low) when the response to the wet regime is tested at both high and low sowing density, and so is the response to the dry regime. (
  • Researchers consider a number of factors in deciding where to publish their research, such as journal reputation, readership and community, speed of publication, and citations. (
  • The strongest factor, which remained after the researchers adjusted for the racial makeup of the neighborhoods, was social capital, which measures the degree of civic engagement among residents along with other factors. (
  • The researchers found that each of the three factors was linked to an increased risk of headache problems, after controlling for the effects of the other two lifestyle factors, as well as age and gender. (
  • The researchers first decided which risk factors to assess. (
  • The factoring of biprimes is proposed as a framework for exploring unconstrained optimization algorithms. (
  • This kind of structured factors allow a more nuanced analysis of determinants of the security returns, in particular, they allow to study clustering structures in security returns as well as their determinants. (
  • Are more data always better for factor analysis? (
  • Currently, neurotrophic factors are being intensely studied for use in bioartificial nerve conduits because they are necessary in vivo for directing axon growth and regeneration. (