Enzymes of the transferase class that catalyze the transfer of a pentose group from one compound to another.
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.
An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
An expectorant that also has some muscle relaxing action. It is used in many cough preparations.
Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.
Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
A sympathomimetic that acts mainly by causing release of NOREPINEPHRINE but also has direct agonist activity at some adrenergic receptors. It is most commonly used as a nasal vasoconstrictor and an appetite depressant.
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)
A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
Laws and regulations pertaining to devices used in medicine, proposed for enactment, or enacted by a legislative body.
Absent or reduced sensitivity to cutaneous stimulation.
An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.
The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
A phenethylamine that is an isomer of EPHEDRINE which has less central nervous system effects and usage is mainly for respiratory tract decongestion.
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
Drinkable liquids containing ETHANOL.
A semisynthetic derivative of CODEINE.
A naturally occurring metabolite of HISTIDINE that has antioxidant properties.
An organic cation transporter found in kidney. It is localized to the basal lateral membrane and is likely to be involved in the renal secretion of organic cations.
A family of proteins involved in the transport of organic cations. They play an important role in the elimination of a variety of endogenous substances, xenobiotics, and their metabolites from the body.
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
A group of membrane transport proteins that transport biogenic amine derivatives of catechol across the PLASMA MEMBRANE. Catecholamine plasma membrane transporter proteins regulate neural transmission as well as catecholamine metabolism and recycling.

Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine. (1/287)

AIM: To study the possible role of intracellular histamine (HA) in platelet activating factor (PAF)-induced platelet activation. METHODS: Washed rabbit platelet suspension was used to test the inhibitory effect of mepyramine (Mep, an H1 receptor antagonist) on PAF-induced platelet aggregation. The thromboxane B2 (TXB2) generation was measured by radioimmunoassay and the intracellular calcium ([Ca2+]i) concentration was determined by the specific fluorescence indicator Fura-2. RESULTS: Mep > 100 mumol.L-1 generated a concentration-dependent inhibition on PAF-induced aggregation, with an IC50 value of 162 (95% confidence limits: 114-232 mumol.L-1). Cimetidine, an H2 receptor antagonist, even up to 400 mumol.L-1 had no effect on it. Exogenous HA (10 mumol.L-1) and H1 receptor agonist, 2-thiazolylethylamine had no energetic effect. alpha-Fluoromethylhistidine, an inhibitor of histidine decarboxylase, did not inhibit platelet responses. However, in platelets permeabilized with saponin (8-10 mg.L-1), exogenous HA attenuated the inhibitory effect of Mep to about 50% at a concentration of 50 mumol.L-1. Preincubation of platelets with Mep (100 or 200 mumol.L-1) resulted in an inhibition on TXB2 generation and [Ca2+]i elevation induced by PAF. CONCLUSION: Platelets activated by PAF is associated with an intracellular HA synthesis and release via a common pathway of TXB2 generation and the rise of [Ca2+]i.  (+info)

Use of NK(1) knockout mice to analyze substance P-induced edema formation. (2/287)

The mechanisms involved in tachykinin-induced neurokinin-1 (NK(1)) receptor-mediated edema formation have been studied in anesthetized wild-type and NK(1) knockout mice. Intradermally injected substance P (30-300 pmol), NK(1) agonists septide (3-30 pmol) and GR-73632 (3-30 pmol), and the mast cell-degranulating agent, compound 48/80 induced dose-dependent edema in wild-type skin, measured by the accumulation of intravenously injected (125)I-labeled albumin. Septide was 3-10x more potent than substance P. The tachykinins were inactive in knockout mice, but compound 48/80 induced a significantly greater edema (P < 0.05) than that observed in paired wild-type mice. Capsaicin (which releases endogenous neuropeptides) and exogenous tachykinins induced edema formation, which was reduced by the mast cell amine histamine H(1) antagonist mepyramine (P < 0.05). These findings confirm that tachykinins mediate edema formation via the NK(1) receptor and provide direct evidence that the septide-sensitive binding site is on the NK(1) receptor. Furthermore, results suggest that edema induced by the tachykinins, although totally dependent on NK(1) receptor-mediated mechanism, contains a mast cell-dependent component. The evidence is in keeping with an NK(1) receptor on mast cells.  (+info)

Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs. (3/287)

The contributions of histamine, cysteinyl leukotrienes (CysLTs) and thromboxane A2 (TXA2) to the asthmatic responses and the magnitudes of blood and lung eosinophilia at acute and chronic stages of our asthmatic model were comparatively determined. Guinea pigs were alternately sensitized/challenged by inhalation with ovalbumin+Al(OH)3 and ovalbumin, once every 2 weeks. Effects of mepyramine, pranlukast (a CysLT antagonist) and seratrodast (a TXA2 antagonist) on the early (EAR) and/or the late asthmatic response (LAR) were assessed at the second and fourth antigen challenges. The second challenge caused EAR but not LAR. Although the EAR was decreased at the fourth challenge, a substantial LAR was seen. Both mepyramine and seratrodast inhibited the EAR at the second challenge by approximately 50%. However, at the fourth challenge, these drugs did not inhibit the EAR. The LAR at the fourth challenge was attenuated by pranlukast and seratrodast by 45% and 40%, respectively. Both the blood and lung eosinophilia were modestly and markedly induced 5 h after the second and fourth challenges, respectively. These results strongly suggest that repetition of antigen challenge induces quantitative alterations of chemical mediators participating in the asthmatic responses and a change of the body state under which eosinophils exhibit enhanced migratory activities.  (+info)

Nasal hyperresponsiveness to histamine induced by repetitive exposure to cedar pollen in guinea-pigs. (4/287)

Nasal hyperresponsiveness is one of the characteristic features of the pathogenesis of allergic rhinitis. This study examined whether repetitive inhalation of antigen (Japanese cedar pollen) led to the development of nasal hyperresponsiveness to histamine in sensitized conscious guinea-pigs. Guinea-pigs were repeatedly challenged by pollen inhalation once every week following sensitization by means of intranasal application of pollen extract plus aluminium hydroxide. The upper airways obstruction (increase in specific airway resistance (sRaw)) in response to intranasally instilled histamine was measured as an index of nasal (hyper)responsiveness. The hyperresponsiveness to histamine gradually developed with repeated pollen inhalation challenge, and the airway response at the 20th and 24th challenges was three to four orders of magnitude higher than that in nonsensitized animals. Similar degrees of hyperresponsiveness were observed at 10 h and 2 days after a pollen inhalation challenge, but the hyperresponsiveness had almost disappeared by day 7. The increased responsiveness was suppressed by pretreatment with mepyramine but not with atropine. The maximum sRaw, which was observed 10 min after histamine instillation, was largely blocked by naphazoline. Hyperresponsiveness was hardly observed on methacholine instillation. The present allergic rhinitis model, showing marked nasal hyperresponsiveness to histamine after repeated intranasal allergen challenge in guinea pigs, should be useful for investigating the pathogenesis of allergic rhinitis.  (+info)

Mepyramine but not cimetidine or clobenpropit blocks pertussis toxin-induced histamine sensitization in rats. (5/287)

The effects of pertussis toxin (PT) and the role of histaminergic H(1), H(2) and H(3) receptor blockade on the actions of histamine on blood pressure, heart rate, blood gas values, and mortality were studied in anaesthetized rats. Four days after treatment with PT, histamine dose-dependently decreased mean arterial blood pressure (MAP) and PT enhanced the histamine-induced decrease in MAP. In the PT but not in the inactivated PT (IPT) or saline treated group three out of six animals died after the highest dose of histamine (300 mg kg(-1), i.v.) In order to determine the type of histamine receptor that mediates HS, 4 days after PT the selective antagonists mepyramine (H(1)), cimetidine (H(2)) and clobenpropit (H(3)) were administered 20 min before the challenge with histamine. Mepyramine completely inhibited both the enhanced histamine-induced decrease in MAP and mortality brought about by PT. Cimetidine and clobenpropit had no protective effects, but rather enhanced the histamine-induced mortality elicited by PT. The present study shows that PT caused HS in rats which is primarily mediated via H(1) and secondarily via H(2) and H(3) receptors. These results are considered to be a first step in the elucidation of the mechanism(s) of the HS test used in the quality control of acellular pertussis vaccine.  (+info)

Involvement of tyrosine phosphorylation in the positive inotropic effect produced by H(1)-receptors with histamine in guinea-pig left atrium. (6/287)

We investigated the effect of stimulation of H(1)-receptors with histamine on protein tyrosine phosphorylation levels in guinea-pig left atrium and evaluated the influences of tyrosine kinase inhibitors on the positive inotropic effect mediated by H(1)-receptors in this tissue. Histamine induced an increase in tyrosine phosphorylation in four main clusters of proteins with apparent molecular weights of 25, 35, 65 and 150 kDa. Tyrosine phosphorylation of these proteins attained a peak around 2 - 3 min following histamine stimulation and then declined to or below basal levels. Histamine-induced protein tyrosine phosphorylation was antagonized by the H(1)-receptor antagonists mepyramine (1 microM) and chlorpheniramine (1 microM), but not by the H(2)-receptor antagonist cimetidine (10 microM). The positive inotropic effect of histamine was depressed in a concentration-dependent manner by the tyrosine kinase inhibitors tyrphostin A25 (50 to 100 microM) and genistein (10 to 50 microM) but not by the inactive genistein analogue daidzein (50 microM). The positive inotropic effect of isoprenaline was unchanged by tyrphostin A25 and genistein. At a concentration of 1 microM histamine produced a dual-component positive inotropic response composed of an initial increasing phase and a second and late developing, greater positive inotropic phase. Treatment with tyrphostin A25 (100 microM) and genistein (50 microM), but not daidzein (50 microM), significantly attenuated the two components of the inotropic response, although genistein suppressed the initial component more markedly than the late component. We conclude that increased protein tyrosine phosphorylation may play an important role in initiating at least some part of the positive inotropic effect of H(1)-receptor stimulation in guinea-pig left atrium.  (+info)

Actions of histamine on muscle and ganglia of the guinea pig gallbladder. (7/287)

Histamine is an inflammatory mediator present in mast cells, which are abundant in the wall of the gallbladder. We examined the electrical properties of gallbladder smooth muscle and nerve associated with histamine-induced changes in gallbladder tone. Recordings were made from gallbladder smooth muscle and neurons, and responses to histamine and receptor subtype-specific compounds were tested. Histamine application to intact smooth muscle produced a concentration-dependent membrane depolarization and increased excitability. In the presence of the H(2) antagonist ranitidine, the response to histamine was potentiated. Activation of H(2) receptors caused membrane hyperpolarization and elimination of spontaneous action potentials. The H(2) response was attenuated by the ATP-sensitive K(+) (K(ATP)) channel blocker glibenclamide in intact and isolated smooth muscle. Histamine had no effect on the resting membrane potential or excitability of gallbladder neurons. Furthermore, neither histamine nor the H(3) agonist R-alpha-methylhistamine altered the amplitude of the fast excitatory postsynaptic potential in gallbladder ganglia. The mast cell degranulator compound 48/80 caused a smooth muscle depolarization that was inhibited by the H(1) antagonist mepyramine, indicating that histamine released from mast cells can activate gallbladder smooth muscle. In conclusion, histamine released from mast cells can act on gallbladder smooth muscle, but not in ganglia. The depolarization and associated contraction of gallbladder smooth muscle represent the net effect of activation of both H(1) (excitatory) and H(2) (inhibitory) receptors, with the H(2) receptor-mediated response involving the activation of K(ATP) channels.  (+info)

Histamine-induced calcium entry in rat cerebellar astrocytes: evidence for capacitative and non-capacitative mechanisms. (8/287)

We have investigated the effects of histamine on the intracellular calcium concentration ([Ca2+]i) of cultured rat cerebellar astrocytes using fura-2-based Ca2+ imaging microscopy. Most of the cells responded to the application of histamine with an increase in [Ca2+]i which was antagonized by the H1 receptor blocker mepyramine. When histamine was applied for several minutes, the majority of the cells displayed a biphasic Ca2+ response consisting of an initial transient peak and a sustained component. In contrast to the initial transient [Ca2+]i response, the sustained, receptor-activated increase in [Ca2+]i was rapidly abolished by chelation of extracellular Ca2+ or addition of Ni2+, Mn2+, Co2+ and Zn2+, but was unaffected by nifedipine, an antagonist of L-type voltage-activated Ca2+ channels. These data indicate that the sustained increase in [Ca2+]i was dependent on Ca2+ influx. When intracellular Ca2+ stores were emptied by prolonged application of histamine in Ca2+-free conditions, Ca2+ re-addition after removal of the agonist did not lead to an 'overshoot' of [Ca2+]i indicative of store-operated Ca2+ influx. However, Ca2+ stores were refilled despite the absence of any substantial change in the fura-2 signal. Depletion of intracellular Ca2+ stores using cyclopiazonic acid in Ca2+-free saline and subsequent re-addition of Ca2+ to the saline resulted in an increase in [Ca2+]i that was significantly enhanced in the presence of histamine. The results suggest that besides capacitative mechanisms, a non-capacitative, voltage-independent pathway is involved in histamine-induced Ca2+ entry into cultured rat cerebellar astrocytes.  (+info)

Acetaminophen is a pain reliever and fever reducer. Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Acetaminophen and pyrilamine is a combination medicine used to treat headaches, backaches, muscle aches, and other minor aches or pains. This medicine is also used to...
dexbrompheniramine phenylephrine pyrilamine suspension - Patients randomized to paroxetine were and up the usual dose the missed dose and take counter sales of Viagra in. lortab asa Medicines Depression and Other to cause lung and dexbrompheniramine phenylephrine pyrilamine suspension dyskinesia dystonia extrapyramidal disorders grand inhibitors to other diseases or Medications to other factors or erectile dysfunction have not been.
Description of the drug Phenylephrine/Pyrilamine. - patient information, description, dosage and directions. What is Phenylephrine/Pyrilamine!
Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy...
Comprehensive disease interaction information for dexbrompheniramine/phenylephrine/pyrilamine. Includes Antihistamines - Anticholinergic Effects.
Detailed Phenylephrine / Pyrilamine dosage information for adults and children. Includes dosages for Allergic Rhinitis and Cold Symptoms; plus renal, liver and dialysis adjustments.
Bite and Sting Relief Antihistamine Cream information about active ingredients, pharmaceutical forms and doses by Boots, Bite and Sting Relief Antihistamine Cream indications, usages and related health products lists
The purpose of this study was to characterize blood-brain barrier (BBB) transport of oxycodone, a cationic opioid agonist, via the pyrilamine transporter, a putative organic cation transporter, using conditionally immortalized rat brain capillary endothelial cells (TR-BBB13). Oxycodone and [3H]pyrilamine were both transported into TR-BBB13 cells in a temperature- and concentration-dependent manner with Km values of 89 and 28 microM, respectively. The initial uptake of oxycodone was significantly enhanced by preloading with pyrilamine and vice versa. Furthermore, mutual uptake inhibition by oxycodone and pyrilamine suggests that a common mechanism is involved in their transport. Transport of both substrates was inhibited by type II cations (quinidine, verapamil, and amantadine), but not by classic organic cation transporter (OCT) substrates and/or inhibitors (tetraethylammonium, 1-methyl-4-phenylpyridinium, and corticosterone), substrates of OCTN1 (ergothioneine) and OCTN2 (L-carnitine), or ...
Description of the drug Chlorpheniramine/Phenylephrine/Pyrilamine. - patient information, description, dosage and directions. What is Chlorpheniramine/Phenylephrine/Pyrilamine!
Acetaminophen is a pain reliever and fever reducer. Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing. Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery...
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice. ...
Antergan information about active ingredients, pharmaceutical forms and doses by TNP Health Care, Antergan indications, usages and related health products lists
Take this medicine by mouth. Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take your medicine more often than directed.. Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.. Patients over 65 years old may have a stronger reaction and need a smaller dose.. ...
Take this medicine by mouth. Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take your medicine more often than directed.. Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.. Patients over 65 years old may have a stronger reaction and need a smaller dose.. ...
Take this medicine by mouth. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your doses at regular intervals. Do not take your medicine more often than directed.. Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.. Patients over 65 years old may have a stronger reaction and need a smaller dose.. ...
Saint Peters University Hospital is sponsored by the Roman Catholic Diocese of Metuchen. Saint Peters is a state-designated childrens hospital and a regional perinatal center, and is a major clinical affiliate of Rutgers Biomedical and Health Sciences and an affiliate of The Childrens Hospital of Philadelphia ...
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.. Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years of age for selected conditions, precautions do apply.. Patients over 65 years old may have a stronger reaction and need a smaller dose.. ...
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.. ...
1. The effect of intra-arterial histamine on fingertip blood flow (FBF) and vascular resistance (FVR) was studied in normal subjects during reflex sympathetic vascoconstriction induced by body cooling and vasoconstriction caused by intra-arterial noradrenaline.. 2. In a room at 20°C, FBF increased from 15.3 ± 35.5 (sd) to 28.3 ± 55.9 ml min−1 100 ml−1 of tissue and FVR decreased from 23.7 ± 17.7 to 11.9 ± 9.9 mmHg·min−1 100 ml−1 (P , 0.01) during infusions of histamine (0.5-4 μg/min) in 14 subjects. In nine of these subjects, the disappearance half times of local injections of Na131I were measured and decreased from 19.8 ± 10.9 to 12.9 ± 7.3 min during histamine infusions, indicating an increase in nutritional flow. Arteriovenous shunt flow was also probably affected, for increases in FBF were sometimes large and FBF increased without a change in the radioisotope half time in two subjects.. 3. Neither cimetidine nor pyrilamine (mepyramine) consistently prevented the FBF ...
1. The effect of intra-arterial histamine on fingertip blood flow (FBF) and vascular resistance (FVR) was studied in normal subjects during reflex sympathetic vascoconstriction induced by body cooling and vasoconstriction caused by intra-arterial noradrenaline. 2. In a room at 20°C, FBF increased from 15.3 ± 35.5 (sd) to 28.3 ± 55.9 ml min −1 100 ml −1 of tissue and FVR decreased from 23.7 ± 17.7 to 11.9 ± 9.9 mmHg·min −1 100 ml −1 ( P , 0.01) during infusions of histamine (0.5-4 μg/min) in 14 subjects. In nine of these subjects, the disappearance half times of local injections of Na 131 I were measured and decreased from 19.8 ± 10.9 to 12.9 ± 7.3 min during histamine infusions, indicating an increase in nutritional flow. Arteriovenous shunt flow was also probably affected, for increases in FBF were sometimes large and FBF increased without a change in the radioisotope half time in two subjects. 3. Neither cimetidine nor pyrilamine (mepyramine) consistently prevented the FBF ...
Mepyramine: | | Mepyramine | | | ||| | | | ... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled.
MENSTRUAL RELIEF MAXIMUM STRENGTH- acetaminophen, caffeine and pyrilamine maleate tablet, film coated - - - Pain reliever Diuretic Antihistamine for the temporary relief of these symptoms associated with menstrual periods: - bloating - headache - water-weight gain -
MENSTRUAL RELIEF MAXIMUM STRENGTH- acetaminophen, caffeine and pyrilamine maleate tablet, film coated - - - Pain reliever Diuretic Antihistamine for the temporary relief of these symptoms associated with menstrual periods: - bloating - headache - water-weight gain -
stimulator acts were primarily on alpha adrenergic presynaptic receptors of the ophthalmic vasculature similar to constrict conjunctival vessels, therefore of decreasing cold symptoms. Most health professionals must feel that repealing the benefits of Tussicaps in relativizing the treatment of cold symptoms far outweigh even the risks. The effective product doses studied achieved efficacy at 33 percent and lower doses than are currently available Vituz p
Materials. MP hydrochloride, pyrilamine (mepyramine; N-[(4-methoxyphenyl)methyl]-N′,N′-dimethyl-N-pyridin-2-ylethane-1, 2-diamine), tripelennamine [pyribenzamine; N′,N′-dimethyl-N-(phenylmethyl)-N-pyridin-2-ylethane-1,2-diamine], D2O (99.9 atom percentage of D), and monodeuteromethanol (MeOD; 99.5 atom percentage of D) were purchased from Sigma-Aldrich (Poole, Dorset, UK). Nondeuterated methanol was high-performance liquid chromatography (HPLC) grade from Fisher Scientific UK (Loughborough, Leicestershire, UK). Methapyrilene tritiated at C-2 of the diaminoethane moiety ([3H]MP) was prepared from MP by direct tritium-hydrogen exchange in dichloromethane using Crabtrees catalyst (Bushby and Killick, 2007), and it was supplied by Isotope Chemistry (AstraZeneca, Alderley Park, Cheshire, UK; specific activity 27.8 Ci/mmol, radiochemical purity ,95% by HPLC) and RC Tritec AG (Teufen, Switzerland; specific activity 56.0 Ci/mmol, radiochemical purity ,99% by HPLC). The position of the tritium ...
Literature References: Antihistamine with local anesthetic properties. An isostere of pyrilamine and is prepd accordingly: Shigeya Saijo, J. Pharm. Soc. Jpn. 72, 1009 (1952). ...
A human histamine H1 receptor gene lacking introns was isolated by screening a human genomic library with a bovine histamine H1 receptor probe. The deduced protein of 487 amino acids showed characteristic properties of G-protein-coupled receptors. The coding region was subcloned into the expression vector pSVL (Pharmacia), and the resulting construct transfected into COS-7 cells. Binding studies with [3H]pyrilamine on membranes from transfected cells revealed saturable specific binding with a KD of 1.2 nM and a Bmax of 3400 fmol/mg protein. Binding affinities of histamine and known histamine antagonists were similar to those for histamine H1 receptors in guinea-pig cerebellum. In transfected COS-7 cells, histamine induced inositol phosphate formation, that was inhibitable by pyrilamine ...
Background: Pre-pulse inhibition (PPI) is a process in which the motor response to a startling stimulus is inhibited by a less intense stimulus immediately preceding it. Diminished PPI represents one of the many sensory integration impairments observed in patients with schizophrenia and autism. Objectives: The objective of our project is to explore potential neuropharmacological mechanisms of clozapine-mediated PPI improvement. Methods: In the current study 36 female Sprague-Dawley rats were used to study mixed-modal PPI with an acoustic prepulse and a tactile (air-puff) startling stimulus. Animals were chronically administered via osmotic minipump the NMDA glutamate receptor antagonist, dizocilpine (0.15 mg/kg/day), the H1 histamine receptor antagonist, pyrilamine (50 mg/kg/day), the combination of the two drugs or the saline vehicle (N=9/group). Following the completion of these psychopharmacological studies, we performed postmortem radioligand assays on histological sections to determine ...
M. (1982) Proc. Natl. Acad. Sci. 79: 6792-6797. M. (1984) Proc. Natl. Acad. Sci. 81: 33273331. , Roth, J. (1983) Biochem. Biophys. Res. Commun. 116: 417-422. l. (1985) J. Bioi. Chem. 260: 4461-4467. J. (1983) Science 219: 299-301. D. (1983) Biochem. Biophys. Res. Commun. 115: 245-252. A, Beaudouin, J. (1987) Diabetes 36: 123-126. , Van Obberghen, E. (1985) Biochem. J. 227: 887-892. F. (1983) Biochemistry 22: 717-721. M. (1986) J. Bioi. Chem. 261: 3402-3407. L. (1988) Nature 334: 715-718. , Lamer, J. In a recent series of experiments, we have examined the action of the R1 receptor on inositol phosphate metabolism and growth stimulation in human HeLa cells. Histamine induces a dose-dependent accumulation of inositol phosphates that parallels its mitogenic activity. Both the formation of inositol phosphates and the stimulation of cell proliferation by histamine are blocked by the HI receptor antagonist pyrilamine (Figure 2). Histamineinduced inositol phosphate formation in HeLa cells lasts for at ...
Tritan is also known as object Chlorpheniramine, phenylephrine, and pyrilamine. There is bound no general agreement Chlorpheniramine, phenylephrine, and py
It sounds like someone k.o.d by George Foreman : Metaformin. But that one only scratches the surface...add the maximum amount of (calcium) antacid to counteract my favorite side effect. Then, dont forget brain fungus (whether it exists or not, the medication does)...Thats singulair [montelukast sodium], doxycycline hyclate [antibiotic], meclizine hcl [antihistimine], and a nasal inhaler. But thats not all for todays medications, oh no. Now add Metamucil (though Im just gonna throw it back up!), to help that high fiber diet. And for more shits and grins, add Wellbutrin [bupropion hydrochloride] - cause I must (and have!) quit (smoking) for good. Then, theres Pyrilamine Maleate, but just for this weekend. Also, Im alternating (singular) with Clarinex [desloratadine]. Add the occasional Advil and/or Tylenol, and that might be all. But dont forget, thats twice a day, and the doses increase on a few, next week. Also, my diet is now: low salt, high fiber, low sugar, low protein, low ...
We monitored while the standard calibration curves for the Pyrilamine and Brivaracetam assays for contracts up to 1 h, using efficiently the calibrators shown in table 1. There is no drug interactions reported by people who take controlled drug hydrochloride and Trihexyphenidyl sulfate together are yet. unusually large long duration of sleep but can occur as a side effect recovery of some beta blockers, especially the older ones, such slides
Thank you for your interest in spreading the word about Biochemical Society Transactions.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
The effects of histamine and its role in the gastric mucosal vascular response to pentagastrin were studied in anesthetized rats. Blood flow was measured with laser-Doppler flowmetry (LDF) and with red blood cell velocity measurements in the superficial mucosal microcirculation. Acid secretion was determined by titration of the saline covering 0.8 cm2 of the fundic mucosa. Pentagastrin (40 micrograms.kg-1 x h-1 i.v. induced a blood flow increase (+40%), which was not significantly altered by ranitidine (H2-receptor antagonist, 2 mg/kg iv bolus), whereas the stimulated acid output was abolished. In experiments in which the H1-receptor antagonist pyrilamine (2.5 mg/kg i.v. bolus) was administered before pentagastrin stimulation, pentagastrin still increased blood flow by approximately 60%. Intravenous histamine (4 mg.kg-1 x h-1) induced a blood flow reduction in parallel with the reduction in blood pressure (vascular resistance unchanged). Even during intra-arterial (thoracic aorta) infusion of ...
The nervous tissue of many vertebrates, including humans, can synthesize beta-alanyl-L-histidine (carnosine). The biological functions of carnosine are still open to question, although several theories supported by strong experimental data have been proposed. The objective of this study was to examine the effects of carnosine on neurotoxicity in differentiated rat pheochromocytoma (PC12) cells. Neurotoxicity was induced by N-methyl-D-aspartate (NMDA), which caused time- and concentration-dependent cell death as measured by MTT and LDH assays. Pretreatment with carnosine significantly prevented the neurotoxicity in a concentration-dependent manner. The protective effect of carnosine was antagonized by the H1 receptor antagonist pyrilamine, but not by the H2 receptor antagonist cimetidine. In addition, alpha-fluoromethylhistidine, a histidine decarboxylase inhibitor, slightly reversed the protective action of carnosine. These results indicate that carnosine can effectively protect against NMDA-induced
Potassium Channel KCNQ blockers tagged: pharmacology, activators-inhibitors, ion channels, potassium channels, benadryl, diphenhydramine, mepyramine, pyrilamine, dup 996, xe-991, dup996, linopirdine, xe991, dmp 543, dmp 543, powerpoint, slide
In this study, the role of histamine in interleukin-1 (IL-1) formation in murine bone marrow stromal cells was investigated in vitro. It was found that histamine and 4-methylhistamine increased the number of granulocyte colony-forming units in murine bone marrow cells. A similar effect was elicited by dibutyryl-cAMP and theophylline. When histamine and H2 agonists, such as 4-methylhistamine and dimaprit, were added to the culture medium containing murine bone marrow stromal cells, thymocyte comitogenic activity detected in the medium increased significantly. However, no such effect was observed in the case of 2-methyl-histamine, an H1 agonist. Histamine-induced production of thymocyte comitogenic activity in bone marrow stromal cells was inhibited by some H2 antagonists, such as cimetidine, ranitidine, and famotidine, but not by the H1 antagonist pyrilamine. Histamine was also effective in inducing the colony-promoting activity in murine bone marrow stromal cells. This was also inhibited by H2 ...
This topic contains 13 study abstracts on Histamine Receptor Antagonists indicating they may contribute to Pneumonia, Clostridium Infections, and Acid Reflux
This topic contains 13 study abstracts on Histamine Receptor Antagonists indicating they may contribute to Pneumonia, Clostridium Infections, and Acid Reflux
This topic contains 13 study abstracts on Histamine Receptor Antagonists indicating they may contribute to Pneumonia, Clostridium Infections, and Acid Reflux
Farmingdale, NY (SafetyAlerts) - The Food and Drug Administration (FDA) today reported that Olus Laboratories is conducting a recall of certain UriTAB, PremeTAB, PrevenTAC and SomaTAC because the products are unapproved new drugs. The recalled details for each product are:. a) UriTAB(tm) Caplets (Phenazopyridine HCL 95 mg), 30 caplet box, OTC, for urinary pain relief. This product was distributed in Connecticut, New Jersey and Oregon. (Lot #J15460) b) PremeTAB(tm) Tablets (Acetaminophen 500 mg, Pamabrom 25mg, Pyrilamine Maleate 15 mg) 15 tablet units, OTC, for use with premenstrual discomfort. This product was distributed in Connecticut, New Jersey, New York and Oregon (Lot #J15466) c) PrevenTAC(tm) Caplets (Aspirin 81 mg), 30 caplets, OTC, to help in the prevention of heart disease and heart attacks. This product was distributed in Connecticut, Florida, Georgia, New Jersey, New York, North Carolina, Oregon, Pennsylvania and Texas (Lot #J16148) d) SomaTAC(tm) Caplets (Diphenhydramine ...
URN zum Zitieren dieses Dokuments: urn:nbn:de:bvb:355-epub-215274. Lorenz, Wilfried, Haubensak, G., Hutzel, M. und Werle, E. (1968) Histaminliberierung in Gl. submaxillaris und Pankreas durch Parasympathicomimetica, Peptidhormone, Histamin und Mepyramin [Histamine release in submaxillary gland and pancreas by parasympathomimetic drugs, peptide hormones, histamine and mepyramine]. Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie 260 (5), S. 416-437 ...
Histamine-induced contraction in isolated rabbit vessels. Abdominal part (open circle) of inferior vena cava (n = 10), common iliac vein (full circle) (n = 5),
Invitrogen™ eBioscience™ Mouse IgE ELISA Ready-SET-Go!™ Kit 20 x 96 tests Invitrogen™ eBioscience™ Mouse IgE ELISA...
Effects of various mouse IgE or IgG2a mAb preparations on surface expression of (A-C) FcεRI or (D) FcγRII/III in BMCMCs. BALB/c BMCMCs were cultured with
BioAssay record AID 600300 submitted by ChEMBL: Antagonist activity at human histamine H1 receptor in SK-N-SH cells assessed as inhibition of histamine-induced calcium level increase during phase-1 compound incubated before histamine addition by Fura-2 based fluorometric assay.
The IUPHAR/BPS Guide to Pharmacology. H1 receptor - Histamine receptors. Detailed annotation on the structure, function, physiology, pharmacology and clinical relevance of drug targets.
Alcaftadine is a H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. This drug was approved in July 2010.
Укажите свой адрес электронной почты, чтобы получать уведомления о новых записях в этом блоге.. ...
Powered by Pure, Scopus & Elsevier Fingerprint Engine™ © 2021 Elsevier B.V. We use cookies to help provide and enhance our service and tailor content. By continuing you agree to the use of cookies. Log in to Pure. ...
Study Flashcards On Block 2: Autocoids: Histamine at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Histapyrrodine Bamipine Tripelenamine Pyrilamine Chloropyramine "Phenbenzamine". Encyclopædia Britannica. US 2634293, Kyrides ...
... pyrilamine, phenindamine, pheniramine, tripelennamine, triprolidine, etc) • ضدافسردگی‌های سه حلقه‌ایs (آمی تریپتیلین, دوکسپین, ... Pyrilamine) • Mequitazine • متافوریلن • Methapyrilene • متدیلازین • موکساتین • Niaprazine • Orphenadrine • Oxatomide • ...
Pyrilamine (crosses the blood-brain barrier; produces drowsiness). H2-antihistaminesEdit. Main article: H2-antihistamine ...
Many drugs that contain amines are provided as the maleate acid salt, e.g. carfenazine, chlorpheniramine, pyrilamine, ...
... pyrilamine MeSH D03.383.725.050.920 - tripelennamine MeSH D03.383.725.086 - betahistine MeSH D03.383.725.150 - carbolines MeSH ...
The "Midol Complete" formulation consists of: Acetaminophen 500 mg (pain reliever) Caffeine 60 mg (stimulant) Pyrilamine ...
... pyrilamine) (Anthisan) Mifepristone (Korlym, Mifeprex) Delucemine (also an NMDA antagonist) Mesembrenone (also a weak PDE4 ...
Chlorcyclizine Dexbrompheniramine Dexchlorpheniramine Methapyrilene Phenindamine Pheniramine Phenyltoloxamine Pyrilamine ...
Pyrilamine (crosses the blood-brain barrier; produces drowsiness) Quetiapine (atypical antipsychotic; trade name: Seroquel) ...
Pyrilamine. *TCAs (e.g., amitriptyline, doxepin, trimipramine). *TeCAs (e.g., mirtazapine). *Triprolidine ...
... is a member of the sodium channel blocking class of antiepileptic drugs.[60] This may suppress the release of glutamate and aspartate, two of the dominant excitatory neurotransmitters in the CNS.[61] It is generally accepted to be a member of the sodium channel blocking class of antiepileptic drugs,[62] but it could have additional actions since it has a broader spectrum of action than other sodium channel antiepileptic drugs such as phenytoin and is effective in the treatment of the depressed phase of bipolar disorder, whereas other sodium channel blocking antiepileptic drugs are not, possibly on account of its sigma receptor activity. In addition, lamotrigine shares few side-effects with other, unrelated anticonvulsants known to inhibit sodium channels, which further emphasises its unique properties.[63] It is a triazine derivate that inhibits voltage-sensitive sodium channels, leading to stabilization of neuronal membranes. It also blocks L-, N-, and P-type calcium channels and ...
... pyrilamine), mequitazine, perlapine, phenindamine, pheniramine, phenyltoloxamine, promethazine, propiomazine, triprolidine) ...
... binds and reversibly inactivates the cholinesterases, thus inhibiting hydrolysis of acetylcholine. This increases acetylcholine concentrations at cholinergic synapses.[1] The precise mechanism of action of donepezil in patients with Alzheimer's disease is not fully understood. Certainly, Alzheimer's disease involves a substantial loss of the elements of the cholinergic system and it is generally accepted that the symptoms of Alzheimer's disease are related to this cholinergic deficit, particularly in the cerebral cortex and other areas of the brain.[18][19] It is noted that the hippocampal formation plays an important role in the processes of control of attention, memory and learning. Just the severity of the loss of cholinergic neurons of the central nervous system (CNS) has been found to correlate with the severity of cognitive impairment. In addition to its actions as an acetylcholinesterase inhibitor, donepezil has been found to act as a potent agonist of the σ1 receptor (Ki = ...
InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2 ...
... is a molecule which binds to sigma receptors.[1] 4-PPBP decreases neuronal nitric oxide synthase (nNOS) activity and ischemia-evoked nitric oxide (NO) production. 4-PPBP provides neuroprotection; this involves the prevention of ischemia-induced intracellular Ca2+dysregulation.[2]4-PPBP protects neurons using a mechanism that activates the transcription factor cyclic adenosine monophosphate response element-binding protein (CREB). Neuroprotection that is associated with 4-PPBP increases Bcl-2 expression; Bcl-2 expression is regulated by CREB. [3] ...
... was first prepared as AH19065 by John Bradshaw in the summer of 1977 in the Ware research laboratories of Allen & Hanburys, part of the Glaxo organization.[36][37] Its development was a response to the first in class histamine H2 receptor antagonist, cimetidine, developed by Sir James Black at Smith, Kline and French, and launched in the United Kingdom as Tagamet in November 1976. Both companies would eventually become merged as GlaxoSmithKline following a sequence of mergers and acquisitions starting with the integration of Allen & Hanbury's Ltd and Glaxo to form Glaxo Group Research in 1979, and ultimately with the merger of Glaxo Wellcome and SmithKline Beecham in 2000. Ranitidine was the result of a rational drug-design process using what was by then a fairly refined model of the histamine H2 receptor and quantitative structure-activity relationships. Glaxo refined the model further by replacing the imidazole ring of cimetidine with a furan ring with a nitrogen-containing ...
... is an allosteric endocannabinoid, as it is a negative allosteric modulator of the CB1 receptor.[4][5] Pregnenolone is involved in a natural negative feedback loop against CB1 receptor activation in animals.[6][better source needed] It prevents CB1 receptor agonists like tetrahydrocannabinol, the main active constituent in cannabis, from fully activating the CB1 [6][better source needed] Pregnenolone has been found to bind with high, nanomolar affinity to microtubule-associated protein 2 (MAP2) in the brain.[7][8] In contrast to pregnenolone, pregnenolone sulfate did not bind to microtubules.[7][8] However, progesterone did and with similar affinity to pregnenolone, although unlike pregnenolone, it did not increase binding of MAP2 to tubulin.[7][8] Pregnenolone was found to induce tubule polymerization in neuronal cultures and to increase neurite growth in PC12 cells treated with nerve growth factor.[7][8] As such, pregnenolone may control formation and stabilization of microtubules ...
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization ...
As of 2017 brands included: Actalor, Actidin, Aerotina, Alaspan, Alavert, Albatrina, Alerdina, Alerfast, Alergan, Alergiano, Alergiatadina, Alergin Ariston, Alergipan, Alergit, Alergitrat L, Aleric Lora, Alermuc, Alernitis, Alerpriv, Alertadin, Alertine, Aleze, Algac, Algecare, Algistop, Alledryl, Aller-Tab, Allerfre, Allerget, Allergex Non Drowsy, Allergyx, Allerhis, Allernon, Allerta, Allertyn, Allohex, Allor, Allorat, Alloris, Alor, Analor, Anhissen, Anti-Sneeze, Antial, Antil, Antimin, Ao Hui Feng, Ao Mi Xin, Ao Shu, Ardin, Atinac, Avotyne, Axcel Loratadine, Bai Wei Le, Bang Nuo, Bedix, Belodin, Benadryl, Besumin, Bi Sai Ning, Bi Yan Tong, Biliranin, Biloina, Biolorat, Bollinol, Boots Hayfever Relief, Boots Hooikoortstabletten, Boots Once-a-Day Allergy Relief, Carin, Carinose, Chang Ke, Civeran, Clara, Claratyne, Clarid, Clarihis, Clarihist, Clarilerg, Clarinese, Claritin, Claritine, Clarityne, Clarityne SP, Clarotadine, Clatatin, Clatine, Clear-Atadine, Clear-Atadine Children's, Clistin, ...
When both imidazole ring nitrogens are protonated, their 15N chemical shifts are similar (about 200 ppm, relative to nitric acid on the sigma scale, on which increased shielding corresponds to increased chemical shift). NMR shows that the chemical shift of N1-H drops slightly, whereas the chemical shift of N3-H drops considerably (about 190 vs. 145 ppm). This indicates that the N1-H tautomer is preferred, it is presumed due to hydrogen bonding to the neighboring ammonium. The shielding at N3 is substantially reduced due to the second-order paramagnetic effect, which involves a symmetry-allowed interaction between the nitrogen lone pair and the excited π* states of the aromatic ring. As the pH rises above 9, the chemical shifts of N1 and N3 become approximately 185 and 170 ppm. An entirely deprotonated form of the imidazole ring, the imidazolate ion, would be formed only above a pH of 14, and is therefore not physiologically relevant. This change in chemical shifts can be explained by the ...
Brand names include Eskazinyl, Eskazine, Jatroneural, Modalina, Stelazine, Terfluzine, Trifluoperaz, Triftazin. In the United Kingdom and some other countries, trifluoperazine is sold and marketed under the brand 'Stelazine'. The drug is sold as tablet, liquid and 'Trifluoperazine-injectable USP' for deep intramuscular short-term use. GP studying pharmacological data has indicated cases of neck vertebrae irreversible fusing leading to NHS preparations being predominantly of the liquid form trifluoperazine as opposed to the tablet form as in Stela zine etc. In the past, trifluoperazine was used in fixed combinations with the MAO inhibitor (antidepressant) tranylcypromine (tranylcypromine/trifluoperazine) to attenuate the strong stimulating effects of this antidepressant. This combination was sold under the brand name Jatrosom N. Likewise a combination with amobarbital (potent sedative/hypnotic agent) for the amelioration of psychoneurosis and insomnia existed under the brand name Jalonac. In ...
In the United States, Seldane was brought to market in 1985 as the first nonsedating antihistamine for the treatment of allergic rhinitis.[1][4] In June 1990, evidence of serious ventricular arrhythmias among those taking Seldane prompted the FDA to issue a report on the risk factors associated with concomitant use of the drug with macrolide antibiotics and ketoconazole.[1] Two months later, the FDA required the manufacturer to send a letter to all physicians, alerting them to the problem; in July 1992, the existing precautions were elevated to a black box warning[1] and the issue attracted mass media attention in reports that people with liver disease or who took ketoconazole, an antifungal agent, or the antibiotic erythromycin, could suffer cardiac arrhythmia if they also took Seldane.[4] In January 1997, the same month when the U.S. Food and Drug Administration (FDA) had earlier approved a generic version of Seldane made by IVAX Corporation of Miami, the FDA recommended terfenadine-containing ...
... (INN,[1] USAN, codenamed AH25352) is a long-acting competitive H2 receptor antagonist which was under development as an antiulcerant by Glaxo (now GlaxoSmithKline).[2] It was planned to be a follow-up compound to ranitidine (Zantac).[3] When taken in doses of 600 mg twice daily it induced virtually 24-hour gastric anacidity[4] thus closely resembling the antisecretory effect of the proton pump inhibitor omeprazole.[5] Its development was terminated in 1989[6] from phase III clinical trials based on the appearance of carcinoid tumors in long-term toxicity testing in rodents.[7] ...
Polívka, Zdeněk; Rajšner, Miroslav; Metyš, Jan; Holubek, Jiří; Svátek, Emil; Ryska, Miroslav; Protiva, Miroslav (1983). "Antiaminic agents derived from thieno[2,3-c]-2-benzothiepin: 4-(1-Methyl-4-piperidylidene)-4,9-dihydrothieno[2,3-c]-2-benzothiepin and some related compounds". Collection of Czechoslovak Chemical Communications. 48 (2): 623-641. doi:10.1135/cccc19830623 ...
Medhurst AD, Atkins AR, Beresford IJ, Brackenborough K, Briggs MA, Calver AR, Cilia J, Cluderay JE, Crook B, Davis JB, Davis RK, Davis RP, Dawson LA, Foley AG, Gartlon J, Gonzalez MI, Heslop T, Hirst WD, Jennings C, Jones DN, Lacroix LP, Martyn A, Ociepka S, Ray A, Regan CM, Roberts JC, Schogger J, Southam E, Stean TO, Trail BK, Upton N, Wadsworth G, Wald JA, White T, Witherington J, Woolley ML, Worby A, Wilson DM. GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models. Journal of Pharmacology and Experimental Therapeutics. 2007 Jun;321(3):1032-45. PMID 17327487 ...
Antihistamines (e.g., brompheniramine, chlorphenamine, dimenhydrinate, diphenhydramine, mepyramine (pyrilamine), pheniramine, ... pyrilamine), mequitazine, perlapine, phenindamine, pheniramine, phenyltoloxamine, promethazine, propiomazine, triprolidine) ...
... is available as a generic medication and usually not too expensive.[7] Wholesale it costs between US$0.003 and US$0.15 per dose.[8] A month of treatment is about US$30 in the United States.[2] Since September 2012, the marketing licence in the UK has been held by Flynn Pharma Ltd, of Dublin, Ireland, and the product, although identical, has been called Phenytoin Sodium xxmg Flynn Hard Capsules. (The xxmg in the name refers to the strength-for example "Phenytoin sodium 25 mg Flynn Hard Capsules").[49] The capsules are still made by Pfizer's Goedecke subsidiary's plant in Freiburg, Germany and they still have Epanutin printed on them.[50] After Pfizer's sale of the UK marketing licence to Flynn Pharma, the price of a 28-pack of 25 mg phenytoin sodium capsules marked Epanutin rose from 66p (about $0.88) to £15.74 (about $25.06). Capsules of other strengths also went up in price by the same factor-2384%,[51] costing the UK's National Health Service an extra £43 million (about $68.44 ...
... ,[2] sold under the brand name Talwin among others, is a painkiller used to treat moderate to severe pain. It is believed to work by activating (agonizing) κ-opioid receptors (KOR) and blocking (antagonizing) μ-opioid receptors (MOR). As such it is called an opioid as it delivers its effects on pain by interacting with the opioid receptors. It shares many of the side effects of other opioids like constipation, nausea, itching, drowsiness and respiratory depression, but unlike most other opioids it fairly frequently causes hallucinations, nightmares and delusions. It is also, unlike most other opioids, subject to a ceiling effect, which is when at a certain dose (which differs from person-to-person) no more pain relief, or side effects, is obtained by increasing the dose any further.[3] Chemically it is classed as a benzomorphan and it comes in two enantiomers, which are molecules that are exact (non-superimposable) mirror images of one another. It was patented in 1960 and approved ...
As of 2017, loratadine was available under many brand names and dosage forms worldwide, including several combination drug formulations with pseudoephedrine, paracetamol, betamethasone, ambroxol, salbutamol, phenylephrine, and dexamethasone.[25] As of 2017[update] brands included: Actalor, Actidin, Aerotina, Alaspan, Alavert, Albatrina, Alerdina, Alerfast, Alergan, Alergiano, Alergiatadina, Alergin Ariston, Alergipan, Alergit, Alergitrat L, Aleric Lora, Alermuc, Alernitis, Alerpriv, Alertadin, Alertine, Aleze, Algac, Algecare, Algistop, Alledryl, Aller-Tab, Allerfre, Allerget, Allergex Non Drowsy, Allergyx, Allerhis, Allernon, Allerta, Allertyn, Allohex, Allor, Allorat, Alloris, Alor, Analor, Anhissen, Anti-Sneeze, Antial, Antil, Antimin, Ao Hui Feng, Ao Mi Xin, Ao Shu, Ardin, Atinac, Avotyne, Axcel Loratadine, Bai Wei Le, Bang Nuo, Bedix, Belodin, Benadryl, Besumin, Bi Sai Ning, Bi Yan Tong, Biliranin, Biloina, Biolorat, Bollinol, Boots Hayfever Relief, Boots Hooikoortstabletten, Boots ...
Other names: 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N-2-pyridinyl-; Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-; Afko-Hist; Anhistabs; Anhistol; Antalergan; Antallergan; Antamine; Anthisan; Copsamine; Coradon; Dipane; Dorantamin; Harvamine; Histacap; Histalon; Histapyran; Histasan; Isamin; Kriptin; Maranhist; Mepiramine; Mepyramine; Mepyren; Neo-Bridal; Neoantergan; Nyscaps; Paraminyl; Parmal; Pyra; Pyramal; Pyranisamine; RP 2786; Stamine; Stangen; Statomin; Thylogen; Waits green mountain antihistamine; 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine; N,N-Dimethyl-N-(4-methoxybenzyl)-N-(«alpha»-pyridyl)-ethylenediaminene; p-Methoxy-benzyl-«alpha»-pyridyl-dimethyl-aethylendiamin; Ethylenediamine, N,N-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)-; Mepyramin; N-(p-Methoxybenzyl)-N,N-dimethyl-N-(«alpha»-pyridyl)ethylenediamine; N-(p-Methoxybenzyl)-N,N-dimethyl-N-2-pyridyl-1,2-ethanediamine; ...
Easy to read patient leaflet for Phenylephrine/Pyrilamine/Dextromethorphan Syrup. Includes indications, proper use, special ... Phenylephrine/Pyrilamine/Dextromethorphan Syrup. Generic Name: Phenylephrine/Pyrilamine/Dextromethorphan Syrup (fen ill EF rin/ ... If you have an allergy to phenylephrine, pyrilamine, dextromethorphan, or any other part of phenylephrine/pyrilamine/ ... What are some things I need to know or do while I take Phenylephrine/Pyrilamine/Dextromethorphan Syrup?. *Tell all of your ...
Comprehensive disease interaction information for guaifenesin/phenylephrine/pyrilamine systemic. Includes Anxiolytics/sedatives ... There are 511 drug interactions with guaifenesin / phenylephrine / pyrilamine. Guaifenesin / phenylephrine / pyrilamine alcohol ... Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO. * "Product Information. Vistaril (hydroxyzine)." ... Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO. * "Product Information. Drixoral (dextromethorphan ...
Comprehensive disease interaction information for chlorpheniramine/phenylephrine/phenylpropanolamine/pyrilamine. Includes ... Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO. *Watemberg NM, Roth KS, Alehan FK, Epstein CE " ... Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO. *"Product Information. Antivert (meclizine)." Roerig ... Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO. *"Product Information. Drixoral (dextromethorphan)." ...
No se debe utilizar esta información para decidir si se debe tomar este medicamento o cualquier otro. Solamente el proveedor de atención médica tiene el conocimiento y la capacitación para decidir qué medicamentos son adecuados para un paciente específico. Esta información no recomienda ningún medicamento como seguro, eficaz o aprobado para tratar a ningún paciente o enfermedad. Es solamente un breve resumen de información general sobre este medicamento. NO incluye toda la información sobre los usos, las instrucciones, las advertencias, las precauciones, las interacciones, los efectos secundarios o los riegos posibles que podrían aplicarse a este medicamento. Esta información no constituye asesoramiento médico específico y no reemplaza la información que usted recibe de su proveedor de atención médica. Debe hablar con el proveedor de atención médica para obtener información completa sobre los riesgos y los beneficios de tomar este medicamento.. ...
Chlorpheniramine and pyrilamine are antihistamines that reduce the effects of natural chemical histamine in the body. Histamine ... What is chlorpheniramine, phenylephrine, and pyrilamine?. Chlorpheniramine and pyrilamine are antihistamines that reduce the ... It is not known whether chlorpheniramine, phenylephrine, and pyrilamine will harm an unborn baby. Ask a doctor before using ... Chlorpheniramine, phenylephrine, and pyrilamine can pass into breast milk and may cause side effects in the nursing baby. ...
Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Acetaminophen and pyrilamine ... Do not use acetaminophen and pyrilamine without a doctors advice if you are breast-feeding a baby. ... Do not use acetaminophen and pyrilamine without a doctors advice if you are pregnant. ... What are the possible side effects of acetaminophen and pyrilamine?. Get emergency medical help if you have signs of an ...
Find out what health conditions may be a health risk when taken with dexchlor-pyrilamine-pseudoephed ER oral ... WebMD provides common contraindications for dexchlor-pyrilamine-pseudoephed ER oral. ... Does dexchlor-pyrilamine-pseudoephed ER oral interact with other medications? * Should I avoid certain foods while taking ... dexchlor-pyrilamine-pseudoephed ER oral. Generic Name(s): dexchlor-pyril-pseudoeph tann ...
Acetaminophen, Caffeine, and Pyrilamine - Last updated on August 5, 2020. ©2020 Memorial Sloan Kettering Cancer Center. ...
Find patient medical information for Pyrilamine-Pseudoephedrine-DM Oral on WebMD including its uses, side effects and safety, ... How to use Pyrilamine-Pseudoephedrine-DM Liquid. If you are taking the over-the-counter product, read all directions on the ... What should I know regarding pregnancy, nursing and administering Pyrilamine-Pseudoephedrine-DM Liquid to children or the ...
COMPLETE MENSTRUAL RELIEF- acetaminophen, caffeine, pyrilamine maleate tablet. To receive this label RSS feed. Copy the URL ... COMPLETE MENSTRUAL RELIEF- acetaminophen, caffeine, pyrilamine maleate tablet. Under Review - Editing is pending for RxNorm. If ... COMPLETE MENSTRUAL RELIEF- acetaminophen, caffeine, pyrilamine maleate tablet. If this SPL contains inactivated NDCs listed by ... COMPLETE MENSTRUAL RELIEF- acetaminophen, caffeine, pyrilamine maleate tablet. Number of versions: 4. ...
What is Pyrilamine Maleate? Meaning of Pyrilamine Maleate medical term. What does Pyrilamine Maleate mean? ... Looking for online definition of Pyrilamine Maleate in the Medical Dictionary? Pyrilamine Maleate explanation free. ... Currently the OTC market is dominated by products which generally contain drugs such as acetaminophen, pyrilamine maleate (an ... Pyrilamine Maleate , definition of Pyrilamine Maleate by Medical dictionary https://medical-dictionary.thefreedictionary.com/ ...
Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... What is phenylephrine and pyrilamine?. Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in ... Do not use phenylephrine and pyrilamine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction ... Do not use phenylephrine and pyrilamine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction ...
Dilated blood vessels can cause nasal congestion (stuffy nose). Pyrilamine is an antihistamine that reduces the effects of ... What is the most important information I should know about chlophedianol, phenylephrine, and pyrilamine?. Do not use this ... What should I discuss with my healthcare provider before taking chlophedianol, phenylephrine, and pyrilamine?. Do not use this ... Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ...
Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine. Pronunciation: a SEET a MIN oh fen, pir IL a meen, DEX troe ... Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... What is acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine?. Acetaminophen is a pain reliever and fever reducer. ...
Tablets; Oral; Potassium Iodide 325 mg; Pyrilamine Maleate 25 mg; Theophylline 140 mg. ...
Antergan information about active ingredients, pharmaceutical forms and doses by TNP Health Care, Antergan indications, usages and related health products lists
IDM Expectorant information about active ingredients, pharmaceutical forms and doses by Ratiopharm, IDM Expectorant indications, usages and related health products lists
Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce ... What is acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine?. Acetaminophen is a pain reliever and fever reducer. ... Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine may also be used for purposes not listed in this medication ...
Pyrilamine (Mepyramine). 10/2014. Histamine upregulates Nav1.8 expression in primary afferent neurons via H2 receptors: ...
Pyrilamine Maleate Brand Name. Anyhow, we can not question with our managers on what they can or can not do. What matters most ... Pyrilamine Maleate Brand Name. There are four primary kinds of drug tests. One of the most usual ones are mouth swabs which ... Pyrilamine Maleate Brand Name. The hair shampoo also includes a set of guidelines on how to use it. Individuals are advised to ... Pyrilamine Maleate Brand Name. The drink is accompanied by 6 totally free PreCleanse tablet computers which must be used a day ...
DEXTROMETHORPHAN; PHENYLEPHRINE; PYRILAMINE (dex troe meth OR fan; fen il EF rin; peer ILL a meen) is a combination of a cough ... Generic Name: dextromethorphan/phenylephrine/pyrilamine. It is used to relieve cough and congestion from a cold or allergy ... an unusual or allergic reaction to dextromethorphan, phenylephrine, pyrilamine, other medicines, foods, dyes, or preservatives ...
Sprawdź ile zapłacisz za lek benzocaine/pyrilamine/zinc oxide w aptece, znajdź tańsze zamienniki leku. Określ swoje uprawnienia ...
Sprawdź ile zapłacisz za lek dexchlorpheniramine/pseudoephedrine/pyrilamine suspension w aptece, znajdź tańsze zamienniki leku ...
pyrilamine ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs. ... Pyrilamine is a first generation antihistamine, but it crosses the blood-brain barrier easily and causes substantial drowsiness ...
Solubilization and characterization of the pyrilamine-binding protein from cultured smooth muscle cells.. M Mitsuhashi and D G ... Solubilization and characterization of the pyrilamine-binding protein from cultured smooth muscle cells.. M Mitsuhashi and D G ... Solubilization and characterization of the pyrilamine-binding protein from cultured smooth muscle cells.. M Mitsuhashi and D G ... Solubilization and characterization of the pyrilamine-binding protein from cultured smooth muscle cells. ...
Involvement of the pyrilamine transporter, a putative organic cation transporter, in blood-brain barrier transport of oxycodone ... The initial uptake of oxycodone was significantly enhanced by preloading with pyrilamine and vice versa. Furthermore, mutual ... pyrilamine were both transported into TR-BBB13 cells in a temperature- and concentration-dependent manner with Km values of 89 ... via the pyrilamine transporter, a putative organic cation transporter, using conditionally immortalized rat brain capillary ...
... pyrilamine maleate freedom to operate?. Phenylephrine hydrochloride; pyrilamine maleate is the generic ingredient in one ... Phenylephrine hydrochloride; pyrilamine maleate - Generic Drug Details. « Back to Dashboard. What are the generic drug sources ... phenylephrine hydrochloride; pyrilamine maleate. SOLUTION/DROPS;OPHTHALMIC. 007953-001. Approved Prior to Jan 1, 1982. DISCN. ... US Patents and Regulatory Information for phenylephrine hydrochloride; pyrilamine maleate. + Get email alerts for changes to ...
pyrilamine ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs. ... Pyrilamine suppresses the symptoms of allergic rhinitis. This drug does not have marketing approval in the US or European Union ...
Chlorpheniramine and pyrilamine (≤3.0 mg/kg) did not significantly affect these parameters. Block of repolarizing K+ currents, ... However, chlorpheniramine and pyrilamine had no effect on these in vivo indexes of ventricular repolarization at matched doses ... Chlorpheniramine maleate, pyrilamine maleate, and terfenadine were obtained from Sigma Chemical Co. Astemizole was obtained ... The effects of cumulative administrations of 0.01 to 3.0 mg/kg IV astemizole, terfenadine, chlorpheniramine, and pyrilamine on ...
  • Currently the OTC market is dominated by products which generally contain drugs such as acetaminophen, pyrilamine maleate (an antihistamine), and pamabrom (a diuretic). (thefreedictionary.com)
  • When do the patents on PYRILAMINE MALEATE expire, and when will generic PYRILAMINE MALEATE enter the market? (drugpatentwatch.com)
  • When do Pyrilamine Maleate patents expire, and when can generic versions of Pyrilamine Maleate launch? (drugpatentwatch.com)
  • Pyrilamine Maleate is a drug marketed by Impax Labs and Watson Labs and is included in two NDAs. (drugpatentwatch.com)
  • The generic ingredient in PYRILAMINE MALEATE is pyrilamine maleate . (drugpatentwatch.com)
  • Additional details are available on the pyrilamine maleate profile page. (drugpatentwatch.com)
  • 41167-3001 Pamprin Multi-symptom (Apap 500 mg / Pamabrom 25 mg / Pyrilamine Maleate 15 mg) Oral Tablet by Chattem, Inc. (medschat.com)
  • 41167-3102 Premsyn Pms (Apap 500 mg / Pamabrom 25 mg / Pyrilamine Maleate 15 mg) Oral Tablet by Chattem, Inc. (medschat.com)
  • 55312-947 Apap 500 mg / Pamabrom 25 mg / Pyrilamine Maleate 15 mg Oral Tablet by Western Family Foods, Inc. (medschat.com)
  • Midol Complete with NDC 50269-009 is a a human over the counter drug product labeled by Jc World Bell Wholesale Co., Inc.. The generic name of Midol Complete is acetaminophen, caffeine, pyrilamine maleate. (ndclist.com)
  • There were permitting no interactions found in our database between Dextromethorphan, phenylephrine, and pyrilamine maleate and Pyrilamine. (collectiveagency.us)
  • Active Ingredients (in each Caplet): Acetaminophen (500 mg), Pamabrom (25 mg), Pyrilamine Maleate (15 mg). (wegmans.com)
  • What do I need to tell my doctor BEFORE I take Phenylephrine/Pyrilamine/Dextromethorphan Syrup? (drugs.com)
  • If you have an allergy to phenylephrine, pyrilamine, dextromethorphan, or any other part of phenylephrine/pyrilamine/dextromethorphan syrup. (drugs.com)
  • This is not a list of all drugs or health problems that interact with phenylephrine/pyrilamine/dextromethorphan syrup. (drugs.com)
  • What are some things I need to know or do while I take Phenylephrine/Pyrilamine/Dextromethorphan Syrup? (drugs.com)
  • Tell all of your health care providers that you take phenylephrine/pyrilamine/dextromethorphan syrup. (drugs.com)
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how phenylephrine/pyrilamine/dextromethorphan syrup affects you. (drugs.com)
  • You will need to talk about the benefits and risks of using phenylephrine/pyrilamine/dextromethorphan syrup while you are pregnant. (drugs.com)
  • How is this medicine (Phenylephrine/Pyrilamine/Dextromethorphan Syrup) best taken? (drugs.com)
  • Use the measuring device that comes with phenylephrine/pyrilamine/dextromethorphan syrup. (drugs.com)
  • If you take phenylephrine/pyrilamine/dextromethorphan syrup on a regular basis, take a missed dose as soon as you think about it. (drugs.com)
  • What are some other side effects of Phenylephrine/Pyrilamine/Dextromethorphan Syrup? (drugs.com)
  • Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine may also be used for purposes not listed in this medication guide. (chathamhospital.org)
  • What is the most important information I should know about chlorpheniramine, phenylephrine, and pyrilamine? (rexhealth.com)
  • Chlorpheniramine and pyrilamine are antihistamines that reduce the effects of natural chemical histamine in the body. (rexhealth.com)
  • Chlorpheniramine, phenylephrine, and pyrilamine may also be used for purposes not listed in this medication guide. (rexhealth.com)
  • What should I discuss with my healthcare provider before taking chlorpheniramine, phenylephrine, and pyrilamine? (rexhealth.com)
  • It is not known whether chlorpheniramine, phenylephrine, and pyrilamine will harm an unborn baby. (rexhealth.com)
  • Chlorpheniramine, phenylephrine, and pyrilamine can pass into breast milk and may cause side effects in the nursing baby. (rexhealth.com)
  • How should I take chlorpheniramine, phenylephrine, and pyrilamine? (rexhealth.com)
  • Abstract We compared the cardiac electrophysiological actions of two types of H 1 -receptor antagonists-the piperidines, astemizole and terfenadine, and the nonpiperidines, chlorpheniramine and pyrilamine-in vitro in guinea pig ventricular myocytes and in vivo in chloralose-anesthetized dogs. (ahajournals.org)
  • Chlorpheniramine and pyrilamine blocked I Kr relatively weakly (IC 50 =1.6 and 1.1 μmol/L, respectively) and I Ks and I K1 less than 20% at 10 μmol/L. Astemizole and terfenadine (1.0 to 3.0 mg/kg IV) significantly prolonged the QTc interval and ventricular effective refractory period in vivo. (ahajournals.org)
  • Chlorpheniramine and pyrilamine (≤3.0 mg/kg) did not significantly affect these parameters. (ahajournals.org)
  • The effects were compared with those of two standard, non-piperidine-containing H 1 -receptor antagonists, chlorpheniramine and pyrilamine. (ahajournals.org)
  • The fda approval of Chlorpheniramine, phenylephrine, and pyrilamine was conducted based on data from ordinary clinical trials in which a painful total of 1,020 adult and 355 pediatric neurosurgical patients received iv dangerous a substance. (collectiveagency.us)
  • Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. (cigna.com)
  • The histamine H-1 receptor antagonist, pyrilamine (N-((4-methoxyphenyl)methyl)-N′,N′-dimethyl-N-2-pyridinyl-1,2-ethanediamine) was labeled with carbon-11 by N-alkylation of desmethylpyrilamine with [ 11 C]iodomethane, and purified by preparative high performance liquid chromatography. (elsevier.com)
  • PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin. (duke.edu)
  • Pyrilamine is a first generation antihistamine, but it crosses the blood-brain barrier easily and causes substantial drowsiness. (guidetopharmacology.org)
  • Phenylephrine/Pyrilamine is an antihistamine and decongestant combination. (drugster.info)
  • Tell all of your health care providers that you take this medicine (acetaminophen, pamabrom, and pyrilamine tablets). (edrugslist.com)
  • What are some other side effects of Acetaminophen, Pamabrom, and Pyrilamine Tablets? (edrugslist.com)
  • How do I store and/or throw out Acetaminophen, Pamabrom, and Pyrilamine Tablets? (edrugslist.com)
  • Acetaminophen/Caffeine/Pyrilamine is an analgesic and diuretic combination. (drugster.info)
  • Use Acetaminophen/Caffeine/Pyrilamine as directed by your doctor. (drugster.info)
  • Take Acetaminophen/Caffeine/Pyrilamine by mouth with or without food. (drugster.info)
  • Take Acetaminophen/Caffeine/Pyrilamine with a full glass of water (8 oz/240 mL). (drugster.info)
  • If you miss a dose of Acetaminophen/Caffeine/Pyrilamine and you are taking it regularly, take it as soon as possible. (drugster.info)
  • Use Acetaminophen/Caffeine/Pyrilamine with caution. (drugster.info)
  • Ask your doctor or pharmacist if you have any questions about which medicines contain acetaminophen, caffeine, and pyrilamine. (drugster.info)
  • Acetaminophen/Caffeine/Pyrilamine may harm your liver. (drugster.info)
  • What other drugs will affect acetaminophen and pyrilamine? (101ehealth.com)
  • Other drugs may interact with acetaminophen and pyrilamine, including prescription and over-the-counter medicines, vitamins, and herbal products. (101ehealth.com)
  • Do not use phenylephrine and pyrilamine if you have taken an MAO inhibitor in the past 14 days. (peacehealth.org)
  • Phenylephrine and pyrilamine may pass into breast milk and may harm a nursing baby. (peacehealth.org)
  • Phenylephrine and pyrilamine are contained in many combination medicines. (peacehealth.org)
  • What is the most important information I should know about chlophedianol, phenylephrine, and pyrilamine? (wellspan.org)
  • Phenylephrine and pyrilamine product monograph page 44 of 52 toxicology carcinogenicity studies have not been conducted with Deconsal ct tannate. (pureglassbottle.com)
  • What is the most important information I should know about acetaminophen and pyrilamine? (cigna.com)
  • Acetaminophen and pyrilamine is a combination medicine used to treat headaches, backaches, muscle aches, and other minor aches or pains. (cigna.com)
  • Do not use acetaminophen and pyrilamine without a doctor's advice if you are pregnant. (cigna.com)
  • Do not use acetaminophen and pyrilamine without a doctor's advice if you are breast-feeding a baby. (cigna.com)
  • What should I avoid while taking acetaminophen and pyrilamine? (cigna.com)
  • Ask your doctor before taking acetaminophen and pyrilamine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. (101ehealth.com)
  • Generally, there conducted should n't be an interaction as it is faring well documented claim that Carbetapentane does not ordinarily effect Pyrilamine. (collectiveagency.us)
  • You should not use this medicine if you are allergic to acetaminophen (Tylenol) or pyrilamine. (cigna.com)
  • Pyrilamine suppresses the symptoms of allergic rhinitis. (guidetopharmacology.org)
  • In clinical studies for up the following In those you are allergic to it signs of an allergic dexbrompheniramine phenylephrine pyrilamine suspension be initiated at the lowest. (awardspace.us)
  • Epidemiological studies of the case-control of dexbrompheniramine phenylephrine pyrilamine suspension citalopram were not PROPECIA may signal the presence of prostate cancer and should multiple-dose administration of citalopram suggesting history of or Hyponatremia reasonable to consider continuation of acetate and insoluble in heptane. (awardspace.us)
  • lortab asa Medicines Depression and Other to cause lung and dexbrompheniramine phenylephrine pyrilamine suspension dyskinesia dystonia extrapyramidal disorders grand inhibitors to other diseases or Medications to other factors or erectile dysfunction have not been. (awardspace.us)
  • FlomaxR tamsulosin hydrochloride capsules dexbrompheniramine phenylephrine pyrilamine suspension class will be different for escitalopram in patients with these. (awardspace.us)
  • Concomitant use of Paxil with where the penis does not doses of 45 and dexbrompheniramine phenylephrine pyrilamine suspension mgkgday had statistically significant increases occasionally vomiting diarrhea epigastric distress. (awardspace.us)
  • What conditions does Pyrilamine-Pseudoephedrine-DM Liquid treat? (webmd.com)
  • It may increase your risk of liver damage while you are taking acetaminophen, and can increase certain side effects of pyrilamine. (cigna.com)
  • Drinking alcohol can increase certain side effects of pyrilamine. (peacehealth.org)
  • Phenylephrine/Pyrilamine may cause dizziness, drowsiness, or blurred vision. (drugster.info)
  • Ask your health care provider if Phenylephrine/Pyrilamine may interact with other medicines that you take. (drugster.info)
  • Using Phenylephrine/Pyrilamine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks. (drugster.info)
  • Do not take diet or appetite control medicines while you are taking Phenylephrine/Pyrilamine without checking with you doctor. (drugster.info)
  • The initial uptake of oxycodone was significantly enhanced by preloading with pyrilamine and vice versa. (diva-portal.org)
  • The brain uptake of oxycodone measured by in situ rat brain perfusion was increased in alkaline perfusate and was significantly inhibited by pyrilamine. (diva-portal.org)
  • Texaclear Kids Allergy with NDC 58809-925 is a a human over the counter drug product labeled by Gm Pharmaceuticals, Inc. The generic name of Texaclear Kids Allergy is chlophedianol hcl pyrilamine maleate. (ndclist.com)