Churg-Strauss Syndrome: Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.Vasculitis: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.Pulmonary Eosinophilia: A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.Syndrome: A characteristic symptom complex.Lung Diseases, Fungal: Pulmonary diseases caused by fungal infections, usually through hematogenous spread.Lung Diseases: Pathological processes involving any part of the LUNG.Bronchoscopy: Endoscopic examination, therapy or surgery of the bronchi.Wegener Granulomatosis: A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and kidneys. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against neutrophil proteinase-3 (WEGENER AUTOANTIGEN).Microscopic Polyangiitis: A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.Polyarteritis Nodosa: A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.Antibodies, Antineutrophil Cytoplasmic: Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.Eosinophilic Granuloma: The most benign and common form of Langerhans-cell histiocytosis which involves localized nodular lesions predominantly of the bones but also of the gastric mucosa, small intestine, lungs, or skin, with infiltration by EOSINOPHILS.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Tosyl CompoundsLeukotriene Antagonists: A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.Health Personnel: Men and women working in the provision of health services, whether as individual practitioners or employees of health institutions and programs, whether or not professionally trained, and whether or not subject to public regulation. (From A Discursive Dictionary of Health Care, 1976)Implant Capsular Contracture: The shrinkage of the foreign body encapsulation scar tissue that forms around artificial implants imbedded in body tissues.Receptors, Leukotriene: Cell-surface receptors that bind LEUKOTRIENES with high affinity and trigger intracellular changes influencing the behavior of cells. The leukotriene receptor subtypes have been tentatively named according to their affinities for the endogenous leukotrienes LTB4; LTC4; LTD4; and LTE4.Anti-Asthmatic Agents: Drugs that are used to treat asthma.Systemic Vasculitis: A heterogeneous group of diseases characterized by inflammation and necrosis of the blood vessel walls.Programmed Instruction as Topic: Instruction in which learners progress at their own rate using workbooks, textbooks, or electromechanical devices that provide information in discrete steps, test learning at each step, and provide immediate feedback about achievement. (ERIC, Thesaurus of ERIC Descriptors, 1996).Rheumatology: A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis.Gold Radioisotopes: Unstable isotopes of gold that decay or disintegrate emitting radiation. Au 185-196, 198-201, and 203 are radioactive gold isotopes.Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.Rheumatic Diseases: Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.Mastitis: INFLAMMATION of the BREAST, or MAMMARY GLAND.Periodontics: A dental specialty concerned with the histology, physiology, and pathology of the tissues that support, attach, and surround the teeth, and of the treatment and prevention of disease affecting these tissues.Portraits as Topic: Graphic representations, especially of the face, of real persons, usually posed, living or dead. (From Thesaurus for Graphic Materials II, p540, 1995)Lymphomatoid Granulomatosis: An angiocentric and angiodestructive lymphoproliferative disorder primarily involving the lungs. It is caused by an Epstein-Barr virus-induced transformation of the B-cells, in a T-cell rich environment. Clinically and pathologically it resembles EXTRANODAL NK-T-CELL LYMPHOMA.BostonMassachusettsLarva Migrans, Visceral: A condition produced in man by the prolonged migration of animal nematode larvae in extraintestinal tissues other than skin; characterized by persistent hypereosinophilia, hepatomegaly, and frequently pneumonitis, commonly caused by Toxocara canis and Toxocara cati.Schools, Medical: Educational institutions for individuals specializing in the field of medicine.Wechsler Scales: Tests designed to measure intellectual functioning in children and adults.Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Pulmonary Emphysema: Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.Emphysema: A pathological accumulation of air in tissues or organs.Bronchiolitis Obliterans: Inflammation of the BRONCHIOLES leading to an obstructive lung disease. Bronchioles are characterized by fibrous granulation tissue with bronchial exudates in the lumens. Clinical features include a nonproductive cough and DYSPNEA.Pericarditis: Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.Bronchiectasis: Persistent abnormal dilatation of the bronchi.Transient Tachypnea of the Newborn: Abnormal increase in RESPIRATORY RATE in the newborn. It is self-limiting and attributed to the delayed fetal lung fluid clearance often in CAESAREAN SECTION delivery.Giant Cell Arteritis: A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)Endomyocardial Fibrosis: A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE).Arteritis: INFLAMMATION of any ARTERIES.Hypereosinophilic Syndrome: A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.Gravitation: Acceleration produced by the mutual attraction of two masses, and of magnitude inversely proportional to the square of the distance between the two centers of mass. It is also the force imparted by the earth, moon, or a planet to an object near its surface. (From NASA Thesaurus, 1988)Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Cooking and Eating UtensilsSodium Oxybate: The sodium salt of 4-hydroxybutyric acid. It is used for both induction and maintenance of ANESTHESIA.
... with features of the syndrome including peripheral eosinophilia, pulmonary infiltrates, and less commonly neuropathy, sinusitis ... Leukotriene receptor antagonist-associated Churg-Strauss syndrome may occur in asthma patients being treated with leukotriene ... Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) Leukotriene antagonist Skin lesion James, William; ...
Eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as Churg-Strauss syndrome). Affects medium and small ... Pulmonary-renal syndrome. Individuals who are coughing up blood and have kidney involvement are likely to have granulomatosis ... Temporal artery biopsy showing vasculitis with mononuclear cell infiltrate or granulomatous inflammation, usually with ... Churg J (September 1993). "Large vessel vasculitis". Clin. Exp. Immunol. 93 Suppl 1 (Suppl 1): 11-2. doi:10.1111/j.1365- ...
... formerly known as Churg-Strauss syndrome). Affects medium and small vessels with vascular and extravascular granulomatosis. ... Pulmonary-renal syndrome. Individuals who are coughing up blood and have kidney involvement are likely to have granulomatosis ... infiltrates, cavities microscopic hematuria or RBC casts vessel biopsy shows granulomatous inflammation Peak incidence: ages 40 ... Churg J (September 1993). "Large vessel vasculitis". Clin. Exp. Immunol. 93 Suppl 1 (Suppl 1): 11-2. doi:10.1111/j.1365- ...
Churg-Strauss Syndrome) Croup Cystic Fibrosis Emphysema Foreign Bodies of the Airway Gastroesophageal Reflux Disease Heart ... Aspiration Syndromes Bronchiectasis Bronchiolitis Bronchiolitis obliterans Chronic bronchitis Chronic Obstructive Pulmonary ... in asthma is characterized by an influx of eosinophils during the early-phase reaction and a mixed cellular infiltrate composed ... Failure Idiopathic Pulmonary Arterial Hypertension Inhalation injury Pulmonary Artery Sling Vocal Cord Dysfunction}} ...
"Churg-Strauss syndrome", named after Drs. Jacob Churg and Lotte Strauss who, in 1951, first published about the syndrome using ... eosinophil blood count greater than 1,500/microliter Presence of mononeuropathy or polyneuropathy Unfixed pulmonary infiltrates ... "Churg-Strauss syndrome - Symptoms". Mayo Clinic. Retrieved 30 June 2013. Della Rossa A, Baldini C, Tavoni A, et al. (November ... Hellmich B, Ehlers S, Csernok E, Gross WL (2003). "Update on the pathogenesis of Churg-Strauss syndrome". Clinical and ...
Shulman's syndrome) Eosinophilic granuloma Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome, allergic ... Primary cutaneous coccidioidomycosis Primary cutaneous histoplasmosis Primary pulmonary coccidioidomycosis Primary pulmonary ... Jessner lymphocytic infiltrate of the skin (benign lymphocytic infiltration of the skin, Jessner lymphocytic infiltration of ... Turner syndrome Ulnar-mammary syndrome Van Der Woude syndrome Von Hippel-Lindau syndrome Watson syndrome Werner syndrome (adult ...
... is a rare syndrome that affects small- to medium-sized arteries and veins. Churg-Strauss syndrome, granulomatosis with ... Churg-Strauss syndrome (CSS), or allergic granulomatous angiitis, ... The image below depicts transient pulmonary infiltrates. [9] Transient pulmonary infiltrates in a patient with Churg-Strauss ... Churg-Strauss Syndrome)) and Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) What to Read Next on ...
... is a rare syndrome that affects small- to medium-sized arteries and veins. Churg-Strauss syndrome, granulomatosis with ... Churg-Strauss syndrome (CSS), or allergic granulomatous angiitis, ... Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving ... Churg-Strauss Syndrome)) and Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) What to Read Next on ...
Churg-Strauss syndrome - Learn how this rare blood vessel disease may cause breathing trouble, face pain and a persistent runny ... Migratory spots or lesions on a chest X-ray (pulmonary infiltrates). These lesions typically move from one place to another or ... Churg-Strauss syndrome. Autoimmunity Reviews. 2015;14:341.. *Churg Strauss syndrome. National Organization for Rare Disorders. ... rarediseases.org/rare-diseases/churg-strauss-syndrome/. Accessed June 25, 2016.. *Churg-Strauss syndrome (CSS). American ...
Pulmonary nodules are more often seen in GPA than in EGPA as "patchy" pulmonary infiltrates are more often seen in EGPA. ... Vasculitis: Churg Strauss Syndrome. *Pulmonary Vasculitis (Necrotizing granulomatous vasculitis, Churg-Strauss syndrome, ... Churg Strauss vasculitis (Churg Strauss granulomatosis (CSG); Churg Strauss syndrome; Allergic granulomatosis; ANCA-associated ... Churg Strauss vasculitis (Churg Strauss granulomatosis (CSG); Churg Strauss syndrome; Allergic granulomatosis; ANCA-associated ...
by Archives of Pathology & Laboratory Medicine; Health, general Churg-Strauss syndrome Case studies ... Allergic Granulomatosis Secondary to a Limited Form of Churg-Strauss Syndrome: A Case Report With Histologic and ... and transient pulmonary infiltrates. Churg-Strauss syndrome (CSS) was also labeled allergic granulomatosis and angiitis because ... Churg-Strauss...-a076842421. *APA style: Allergic Granulomatosis Secondary to a Limited Form of Churg-Strauss Syndrome: A Case ...
Churg-Strauss syndrome). *Primary hypereosinophilic syndromes (including pulmonary infiltrates with eosinophilia [Loefflers ... Systemic Vasculitis (esp Churg-Strauss Syndrome). *Primary Immunodeficiencies (esp Hyper-IgE syndrome, Wiskott-Aldrich syndrome ...
"Zafirlukast and Churg-Strauss syndrome." Chest 116 (1999): 266-7. 12. Wechsler ME, Garpestad E, Rlier SR, et al. "Pulmonary ... infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast ... Honsinger RW "Zafirlukast and Churg-Strauss syndrome." JAMA 279 (1998): 1949. 16. Green RL, Vayonis AG "Churg-Strauss syndrome ... "Zafirlukast and Churg-Strauss syndrome." JAMA 279 (1998): 1949. 19. Knoell DL, Lucas J, Allen JN "Churg-Strauss syndrome ...
... with features of the syndrome including peripheral eosinophilia, pulmonary infiltrates, and less commonly neuropathy, sinusitis ... Leukotriene receptor antagonist-associated Churg-Strauss syndrome may occur in asthma patients being treated with leukotriene ... Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) Leukotriene antagonist Skin lesion James, William; ...
The correct answer is A. This patient most likely has Churg-Strauss syndrome (CSS). This form of systemic vasculitis often ... Common findings include eosinophilia, pulmonary infiltrates, skin rash (including LCV, and occasionally a characteristic ... Abril A. Churg-Strauss syndrome: an update. Curr Rheumatol Rep 2011;13:489-95. ... This patients presentation suggests a pulmonary-renal syndrome, the most common causes of which include Goodpastures (anti- ...
Serial pulmonary function tests are helpful in patients with bronchiectasis in GPA, or pulmonary infiltrates in EGPA or MPA. It ... Churg Strauss vasculitis (Churg Strauss granulomatosis (CSG); Churg Strauss syndrome; Allergic granulomatosis; ANCA-associated ... Pulmonary Medicine , * Pulmonary Vasculitis (Necrotizing granulomatous vasculitis, Churg-Strauss syndrome, Microscopic ... Pulmonary Medicine. Pulmonary Vasculitis (Necrotizing granulomatous vasculitis, Churg-Strauss syndrome, Microscopic ...
... pulmonary infiltrates, and sinus abnormalities.1 Conventional treatment with corticosteroids and cyclophosphamide2 controls ... Churg-Strauss Syndrome (CSS) is a small vessel systemic vasculitis, characterised by asthma, peripheral eosinophilia, ...
It typically occurs in conjunction with a history of asthma, eosinophilia, pulmonary infiltrates, and vasculitis, but cases ... Churg-Strauss syndrome was first described by Churg and Strauss in 1951 (3). The annual incidence of CSS in adults ranges ... Churg-Strauss syndrome (CSS), also known as allergic granulomatous angiitis, is a systemic necrotizing vasculitis of the small ... 1. Hamdan MA, Al-Rumaithi S, Tolaymat N, Ionescu G, Al-Ashari M, El-Teraifi H. Churg Strauss syndrome presenting as an ...
Eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome). Palpable purpura, nodules, and ulcers on the ... eosinophilic pulmonary infiltrates, peripheral eosinophilia, and antineutrophil cytoplasmic antibodies.3,4. Erythema multiforme ... Eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome). Palpable purpura, nodules, and ulcers on the ... Eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome) is a small vessel vasculitis that affects males ...
... pulmonary infiltrates) often precede the development of the generalized (systemic) symptoms and findings seen in Churg-Strauss ... Churg-Strauss syndrome is a rare disorder that may affect multiple organ systems, particularly the lungs. The disorder is ... Nonspecific findings associated with Churg-Strauss syndrome typically include flu-like symptoms, such as fever, a general ... Although the exact cause of Churg-Strauss syndrome is unknown, many researchers indicate that abnormal immunologic and ...
Criteria for the classification of Churg-Strauss syndrome (CSS) were developed by comparing 20 patients who had this diagnosis ... non-fixed pulmonary infiltrates on roentgenography, paranasal sinus abnormality, and biopsy containing a blood vessel with ... Criteria for the classification of Churg-Strauss syndrome (CSS) were developed by comparing 20 patients who had this diagnosis ... The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis ...
Transient pulmonary infiltrates on chest imaging studies. *Paranasal sinus abnormalities or nasal polyposis ... Churg-Strauss Syndrome. Systemic Vasculitis. Granulomatosis with Polyangiitis. Vasculitis. Vascular Diseases. Cardiovascular ... Determining Disease Activity Biomarkers in Individuals With Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss). This ... Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) is a rare immune system disorder that causes asthma, an ...
Michael Wechsler Division of Pulmonary and Critical Care Brigham and Womens Hospital Harvard Medical School Boston, ... Similar to Churg-Strauss Syndrome, a majority have asthma, with many having a history of allergies; the airflow obstruction ... Diffuse pulmonary infiltrates on chest x-ray (abnormal x-ray). Lung fluid eosinophilia,25%. Absence of parasitic, fungal or ... While patients present with an elevated white blood cell count, in contrast to other pulmonary eosinophilic syndromes, acute ...
EGPA/Churg Strauss Syndrome is the rarest of the AAVs and is associated with late onset asthma, pulmonary infiltrates, ... of the article was published in the July/August newsletter and reviewed research presented on ANCA vasculitis and pulmonary ...
Churg-Strauss syndrome]] may present with [[asthma]], [[sinusitis]], transient [[pulmonary]] infiltrates and neuropathy ... Churg-Strauss syndrome]]) *[[Atrial fibrillation]] ([[Churg-Strauss syndrome]]) *Non-specific [[ST interval,ST segment]] and [[ ... Cardiac involvement in Churg-Strauss syndrome ,journal=Arthritis Rheum. ,volume=62 ,issue=2 ,pages=627-34 ,year=2010 ,pmid= ... chronic obstructive pulmonary disease (COPD), and the overlap syndrome ,journal=J Am Board Fam Med ,volume=26 ,issue=4 ,pages= ...
Eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as Churg-Strauss syndrome). Affects medium and small ... Pulmonary-renal syndrome. Individuals who are coughing up blood and have kidney involvement are likely to have granulomatosis ... Temporal artery biopsy showing vasculitis with mononuclear cell infiltrate or granulomatous inflammation, usually with ... Churg J (September 1993). "Large vessel vasculitis". Clin. Exp. Immunol. 93 Suppl 1 (Suppl 1): 11-2. doi:10.1111/j.1365- ...
Serial pulmonary function tests are helpful in patients with bronchiectasis in GPA, or pulmonary infiltrates in EGPA or MPA. It ... Pulmonary Medicine Pulmonary Vasculitis (Necrotizing granulomatous vasculitis, Churg-Strauss syndrome, Microscopic polyangiitis ... Close more info about Pulmonary Vasculitis (Necrotizing granulomatous vasculitis, Churg-Strauss syndrome, Microscopic ... Close more info about Pulmonary Vasculitis (Necrotizing granulomatous vasculitis, Churg-Strauss syndrome, Microscopic ...
... such as Churg-Strauss syndrome, acute or chronic eosinophilic pneumonia, tropical pulmonary eosinophilia, and idiopathic ... improving radiographic infiltrates, and improving symptoms and pulmonary function. Retrospective studies and case series ... Pulmonary function testing does not assist in confirmation or exclusion of the diagnosis of ABPA. However, pulmonary function ... other bronchiectasis syndromes, and tropical pulmonary eosinophilia (often caused by filariasis). The laboratory tests used to ...
Pulmonary manifestations, including pulmonary hemorrage, can also be present.. Churg-Strauss syndrome. This is a disorder ... Systemic features can include cutaneous vasculitis lesions, neuropathy, paranasal sinus abnormality, or pulmonary infiltrates. ... and Churg-Strauss syndrome (CSS).. Wegener granulomatosis. Granulomatous inflammation involves the respiratory track and ... Patients can present with a dry cough, hemoptysis, bilateral diffuse lung infiltrate revealed by a chest X ray, sinusitis, ...
Pulmonary manifestations, including pulmonary hemorrage, can also be present.. Churg-Strauss syndrome. This is a disorder ... Systemic features can include cutaneous vasculitis lesions, neuropathy, paranasal sinus abnormality, or pulmonary infiltrates. ... and Churg-Strauss syndrome (CSS).. Wegener granulomatosis. Granulomatous inflammation involves the respiratory track and ... Tricuspid Regurgitation Velocity Unreliable Indicator of Pulmonary Hypertension. *Supplementing Pulmonary Arterial Hypertension ...
Churg-Strauss syndrome, and allergic bronchopulmonary aspergillosis (asthma, immediate cutaneous reactivity to A. fumigatus, ... Subject has segmental atelectasis, lobar consolidation, significant or unstable pulmonary infiltrate, or pneumothorax, ...
  • An EGPA-like syndrome is a rare complication that develops in steroid-dependent patients with asthma who have their oral steroid dose reduced after they start treatment with a leukotriene receptor antagonist (eg, montelukast, zafirlukast). (medscape.com)
  • However, in rare cases, this syndrome has developed when a leukotriene receptor antagonist has been substituted for inhaled steroids ini patients without a history of oral steroid withdrawal. (medscape.com)
  • A biopsy of a person with Churg-Strauss syndrome may show the presence of eosinophils outside of a blood vessel. (mayoclinic.org)
  • If other tests suggest Churg-Strauss syndrome, you may have a small sample of tissue (biopsy) removed for examination under a microscope. (mayoclinic.org)
  • At least 3 out of 5 criteria yields sensitivity and specificity of 95 and 91%: Age at onset ≥ 50 years New onset headache with localized tenderness Temporal artery tenderness or decreased pulsation Elevated ESR ≥ 50 mm/hour Westergren Temporal artery biopsy showing vasculitis with mononuclear cell infiltrate or granulomatous inflammation, usually with multinucleated giant cells These conditions are sometimes considered together with the small vessel vasculitides. (wikipedia.org)
  • 10% on differential white blood cell count, mononeuropathy or polyneuropathy, non-fixed pulmonary infiltrates on imaging, paranasal sinus abnormality and biopsy containing a blood vessel with extravascular eosinophils. (eurorad.org)
  • The primary test for diagnosing Churg-Strauss is a biopsy of the affected skin tissue. (medlexi.com)
  • These included patchy eosinophilic pneumonia and scattered necrotising granulomas with eosinophils involving the pulmonary parenchyma, pulmonary arteries and veins, but unusually, similar granulomas involved several bronchioles with crescentic zones of necrobiotic tissue with eosinophils lining the partial circumference of airways, surrounded by epithelioid histiocytes and occasional giant cells ( fig 1 ). (bmj.com)
  • Chest spiral CT before hospitalization in this centre revealed patchy infiltrates. (who.int)
  • Nonresolving pneumonia, chronic pneumonia and slowly resolving pneumonia are related entities to recurrent pneumonia and have been used in the literature interchangeably to refer to pneumonia with persistence of radiographic abnormalities beyond the expected time course, without interval clearing of the infiltrate. (cancertherapyadvisor.com)
  • Recurrent pneumonia is defined as two or more episodes of nontuberculous pulmonary infection separated by at least a one-month asymptomatic interval, complete radiographic clearing of the infiltrate, or both. (cancertherapyadvisor.com)
  • Nonresolving or slowly resolving pneumonia is loosely defined as a pneumonia that does not improve clinically, or even worsens, despite a minimum of 10 days of adequate antibiotic therapy, or as radiographic infiltrate that does not resolve within 12 weeks. (bmj.com)
  • The hypereosinophilic syndromes represent a group of disorders marked by the sustained overproduction of eosinophils, with eosinophilic infiltration of tissues and mediator release, leading to multiple organic damages. (sciencepublishinggroup.com)
  • This binding activates the complement cascade, which causes polymorphonuclear leukocytes (i.e., neutrophils, basophils, and eosinophils) antigen and monocytes to infiltrate the glomerulus (Brenner & Rector, 1996). (thefreelibrary.com)
  • IgG4-positive plasma cells can be seen in TIN associated with systemic lupus erythematosus, Sjögren syndrome, or anti-neutrophil cytoplasmic antibody-associated vasculitis, which further add diagnostic confusion and difficulties. (jpatholtm.org)
  • Pulmonary Infiltrates showed up in both lungs, I was treated for pneumonia with antibiotics and oxygen, while giving the same "no" answer to that pleasant question: "Are you coughing up anything? (kareninwonderland.com)
  • He sent us for many tests, including her first CT scan, then in June 2002, and that finally showed the white patches all over her lungs, called ground glass infiltrates. (cssassociation.org)
  • Recurrent infections in one anatomic region suggest an anatomic abnormality (such as pulmonary sequestration) or a bronchial obstruction by a tumor or a foreign body. (psychiatryadvisor.com)