Pulmonary Gas Exchange
Ventilation-Perfusion Ratio
Noble Gases
Arrhythmia, Sinus
Oxygen
Carbon Dioxide
Pulmonary Diffusing Capacity
Respiratory Mechanics
Partial Pressure
Respiratory Dead Space
Oxygen Consumption
Respiration
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Gases
The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)
Tidal Volume
Lung
Pulmonary Ventilation
Smoke Inhalation Injury
Respiratory Function Tests
Pulmonary Edema
Physical Exertion
Hepatopulmonary Syndrome
A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).
Hyperventilation
Respiration, Artificial
Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).
Extravascular Lung Water
Water content outside of the lung vasculature. About 80% of a normal lung is made up of water, including intracellular, interstitial, and blood water. Failure to maintain the normal homeostatic fluid exchange between the vascular space and the interstitium of the lungs can result in PULMONARY EDEMA and flooding of the alveolar space.
Cardiac Output
Exercise Test
Hemodynamics
Respiratory Distress Syndrome, Adult
Exercise
Bicycling
Pulmonary Alveoli
Vital Capacity
Respiratory Transport
Dogs
Lactic Acid
Forced Expiratory Volume
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
Lung Volume Measurements
Neon
Positive-Pressure Respiration
Water Loss, Insensible
Plant Transpiration
Acute saline infusion reduces alveolar-capillary membrane conductance and increases airflow obstruction in patients with left ventricular dysfunction. (1/1644)
BACKGROUND: Impaired alveolar-capillary membrane conductance is the major cause for the reduction in pulmonary diffusing capacity for carbon monoxide (DLCO) in heart failure. Whether this reduction is fixed, reflecting pulmonary microvascular damage, or is variable is unknown. The aim of this study was to assess whether DLCO and its subdivisions, alveolar-capillary membrane conductance (DM) and pulmonary capillary blood volume (Vc), were sensitive to changes in intravascular volume. In addition, we examined the effects of volume loading on airflow rates. METHODS AND RESULTS: Ten patients with left ventricular dysfunction (LVD) and 8 healthy volunteers were studied. DM and Vc were determined by the Roughton and Forster method. The forced expiratory volume in 1 second (FEV1), vital capacity, and peak expiratory flow rates (PEFR) were also recorded. In patients with LVD, infusion of 10 mL. kg-1 body wt of 0.9% saline acutely reduced DM (12.0+/-3.3 versus 10.4+/-3.5 mmol. min-1. kPa-1, P<0.005), FEV1 (2.3+/-0.4 versus 2.1+/-0.4 L, P<0.0005), and PEFR (446+/-55 versus 414+/-56 L. min-1, P<0.005). All pulmonary function tests had returned to baseline values 24 hours later. In normal subjects, saline infusion had no measurable effect on lung function. CONCLUSIONS: Acute intravascular volume expansion impairs alveolar-capillary membrane function and increases airflow obstruction in patients with LVD but not in normal subjects. Thus, the abnormalities of pulmonary diffusion in heart failure, which were believed to be fixed, also have a variable component that could be amenable to therapeutic intervention. (+info)Peripheral muscle ergoreceptors and ventilatory response during exercise recovery in heart failure. (2/1644)
Recent studies have suggested that the increased ventilatory response during exercise in patients with chronic heart failure was related to the activation of muscle metaboreceptors. To address this issue, 23 patients with heart failure and 7 normal subjects performed arm and leg bicycle exercises with and without cuff inflation around the arms or the thighs during recovery. Obstruction slightly reduced ventilation and gas exchange variables at recovery but did not change the kinetics of recovery of these parameters compared with nonobstructed recovery: half-time of ventilation recovery was 175 +/- 54 to 176 +/- 40 s in patients and 155 +/- 66 to 127 +/- 13 s in controls (P < 0.05, patients vs. controls, not significant within each group from baseline to obstructed recovery). We conclude that muscle metaboreceptor activation does not seem to play a role in the exertion hyperventilation of patients with heart failure. (+info)Continuous arterial P(O2) and P(CO2) measurements in swine during nitrous oxide and xenon elimination: prevention of diffusion hypoxia. (3/1644)
BACKGROUND: During nitrous oxide (N2O) elimination, arterial oxygen tension (PaO2) decreases because of the phenomenon commonly called diffusive hypoxia. The authors questioned whether similar effects occur during xenon elimination. METHODS: Nineteen anesthetized and paralyzed pigs were mechanically ventilated randomly for 30 min using inspiratory gas mixtures of 30% oxygen and either 70% N2O or xenon. The inspiratory gas was replaced by a mixture of 70% nitrogen and 30% oxygen. PaO2 and carbon dioxide tensions were recorded continuously using an indwelling arterial sensor. RESULTS: The PaO2 decreased from 119+/-10 mm Hg to 102+/-12 mm Hg (mean+/-SD) during N2O washout (P<0.01) and from 116+/-9 mm Hg to 110+/-8 mm Hg during xenon elimination (P<0.01), with a significant difference (P<0.01) between baseline and minimum PaO2 values (deltaPaO2, 17+/-6 mm Hg during N2O washout and 6+/-3 mm Hg during xenon washout). The PaCO2 value also decreased (from 39.3+/-6.3 mm Hg to 37.6+/-5.8 mm Hg) during N2O washout (P<0.01) and during xenon elimination (from 35.4+/-1.6 mm Hg to 34.9+/-1.6 mm Hg; P< 0.01). The deltaPaCO2 was 1.7+/-0.9 mm Hg in the N2O group and 0.5+/-0.3 mm Hg in the xenon group (P<0.01). CONCLUSION: Diffusive hypoxia is unlikely to occur during recovery from xenon anesthesia, probably because of the low blood solubility of this gas. (+info)Breathing patterns during slow and fast ramp exercise in man. (4/1644)
Breathing frequency (fb), tidal volume (VT), and respiratory timing during slow (SR, 8 W min-1) and fast (FR, 65 W min-1) ramp exercise to exhaustion on a cycle ergometer was examined in seven healthy male subjects. Expiratory ventilation (VE), pulmonary gas exchange (VO2 and VCO2) and end-tidal gas tensions (PET,O2 and PET,CO2) were determined using breath-by-breath techniques. Arterialized venous blood was sampled from a dorsal hand vein at 2 min intervals during SR and 30 s intervals during FR and analysed for arterial plasma PCO2 (PaCO2). PET,CO2 increased with increasing work rates (WRs) below the ventilatory threshold (VT); at WRs > or = 90% VO2,max, PET,CO2 was reduced (P < 0.05) below 0 W values in SR but not in FR.fb and VT were similar for SR and FR at all submaximal WRs, resulting in a similar VE. At exhaustion VE was similar but fb was higher (P < 0.05) and VT was lower (P < 0.05) in SR (fb, 51 +/- 10 breaths min-1; VT, 2590 +/- 590 ml) than in FR (fb, 42 +/- 8 breaths min-1; VT, 3050 +/- 470 ml). The time of expiration (TE) decreased with increasing WR, but there was no difference between SR and FR. The time of inspiration (TI) decreased at exercise intensities > or = VT; at exhaustion, TI was shorter (P < 0.05) during SR (0.512 +/- 0.097 s) than during FR (0.753 +/- 0.100 s). The TI to total breath duration (TI/TTot) and the inspiratory flow (VT/TI) were similar during SR and FR at all submaximal exercise intensities; at VO2,max, TI/TTot was lower (P < 0.05) and VT/TI was higher (P < 0.05) during SR (TI/TTot, 0.473 +/- 0.030; VT/TI, 5.092 +/- 0.377 l s-1) than during FR (TI/TTot, 0.567 +/- 0.050; VT/TI, 4.117 +/- 0.635 l s-1). These results suggest that during progressive exercise, breathing pattern and respiratory timing may be determined, at least at submaximal work rates, independently of alveolar and arterial PCO2. (+info)Airway closure, atelectasis and gas exchange during general anaesthesia. (5/1644)
Airway closure and the formation of atelectasis have been proposed as important contributors to impairment of gas exchange during general anaesthesia. We have elucidated the relationships between each of these two mechanisms and gas exchange. We studied 35 adults with healthy lungs, undergoing elective surgery. Airway closure was measured using the foreign gas bolus technique, atelectasis was estimated by analysis of computed x-ray tomography, and ventilation-perfusion distribution (VA/Q) was assessed by the multiple inert gas elimination technique. The difference between closing volume and expiratory reserve volume (CV-ERV) increased from the awake to the anaesthetized state. Linear correlations were found between atelectasis and shunt (r = 0.68, P < 0.001), and between CV-ERV and the amount of perfusion to poorly ventilated lung units ("low Va/Q", r = 0.57, P = 0.001). Taken together, the amount of atelectasis and airway closure may explain 75% of the deterioration in PaO2. There was no significant correlation between CV-ERV and atelectasis. We conclude that in anaesthetized adults with healthy lungs, undergoing mechanical ventilation, both airway closure and atelectasis contributed to impairment of gas exchange. Atelectasis and airway closure do not seem to be closely related. (+info)Cardiopulmonary resuscitation: effect of CPAP on gas exchange during chest compressions. (6/1644)
BACKGROUND: Conventional cardiopulmonary resuscitation (CPR) includes 80-100/min precordial compressions with intermittent positive pressure ventilation (IPPV) after every fifth compression. To prevent gastric insufflation, chest compressions are held during IPPV if the patient is not intubated. Elimination of IPPV would simplify CPR and might offer physiologic advantages, but compression-induced ventilation without IPPV has been shown to result in hypercapnia. The authors hypothesized that application of continuous positive airway pressure (CPAP) might increase CO2 elimination during chest compressions. METHODS: After appropriate instrumentation and measurement of baseline data, ventricular fibrillation was induced in 18 pigs. Conventional CPR was performed as a control (CPR(C)) for 5 min. Pauses were then discontinued, and animals were assigned randomly to receive alternate trials of uninterrupted chest compressions at a rate of 80/min without IPPV, either at atmospheric airway pressure (CPR(ATM)) or with CPAP (CPR(CPAP)). CPAP was adjusted to produce a minute ventilation of 75% of the animal's baseline ventilation. Data were summarized as mean +/- SD and compared with Student t test for paired observations. RESULTS: During CPR without IPPV, CPAP decreased PaCO2 (55+/-28 vs. 100+/-16 mmHg) and increased SaO2 (0.86+/-0.19 vs. 0.50+/-0.18%; P < 0.001). CPAP also increased arteriovenous oxygen content difference (10.7+/-3.1 vs. 5.5+/-2.3 ml/dl blood) and CO2 elimination (120+/-20 vs. 12+/-20 ml/min; P < 0.01). Differences between CPR(CPAP) and CPR(ATM) in aortic blood pressure, cardiac output, and stroke volume were not significant. CONCLUSIONS: Mechanical ventilation may not be necessary during CPR as long as CPAP is applied. Discontinuation of IPPV will simplify CPR and may offer physiologic advantage. (+info)Hemodynamic effects of bilevel nasal positive airway pressure ventilation in patients with heart failure. (7/1644)
AIMS: Benefits of nasal continuous positive airway pressure (CPAP) in patients presenting with chronic heart failure (CHF) are controversial. The purpose of this study was to compare the hemodynamic effects of CPAP and bilevel positive airway pressure (BiPAP) in patients with or without CHF. METHODS AND RESULTS: Twenty patients with CHF and 7 with normal left ventricular function underwent cardiac catheterization. Measurements were made before and after three 20-min periods of BiPAP: expiratory positive airway pressure (EPAP) = 8 cm H2O and inspiratory positive airway pressure (IPAP) = 12 cm H2O, EPAP = 10 cm H2O and IPAP = 15 cm H2O, and CPAP = EPAP = IPAP = 10 cm H2O administered in random order. Positive pressure ventilation decreased cardiac output (CO) and stroke volume. No change was observed in either pulmonary or systemic arterial pressure. There was no difference in the hemodynamic effects of the three ventilation settings. Only mean pulmonary wedge pressure (MPWP) and heart rate were lower with CPAP than with BiPAP. CO decreased only in patients with low MPWP (+info)A chest wall restrictor to study effects on pulmonary function and exercise. 2. The energetics of restrictive breathing. (8/1644)
Chest wall restriction, whether caused by disease or mechanical constraints such as protective outerwear, can cause decrements in pulmonary function and exercise capacity. However, the study of the oxygen cost associated with mechanical chest restriction has so far been purely qualitative. The previous paper in this series described a device to impose external chest wall restriction, its effects on forced spirometric volumes, and its test-retest reliability. The purpose of this experiment was to measure the oxygen cost associated with varied levels of external chest wall restriction. Oxygen uptake and electromyogram (EMG) of the external intercostals were recorded during chest restriction in 10 healthy males. Subjects rested for 9 min before undergoing volitional isocapnic hyperpnea for 6 min. Subjects breathed at minute ventilations (V.I) of 30, 60, and 90 liters/min with chest wall loads of 0, 25, 50 and 75 mm Hg applied. Frequency of breathing was set at 15, 30, and 45 breaths per minute with a constant tidal volume (VT) of 2 liters. Oxygen uptake was measured continuously at rest and throughout the hyperventilation bouts, while controlling V.I and VT. Integrated EMG (IEMG) from the 3rd intercostal space was recorded during each minute of rest and hyperventilation. Two-way ANOVA with repeated measures revealed that chest wall loading and hyperpnea significantly increased V.O2 values (p < 0.01). External intercostal IEMG levels were significantly increased (p < 0.05) at higher restrictive load (50 and 75 mm Hg) and at the highest minute ventilation (90 liters/min). These data suggest that there is a significant and quantifiable increase in the oxygen cost associated with external chest wall restriction which is directly related to the level of chest wall restriction. (+info)Method for determination of pulmonary gas exchange in connection with birth.
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August Krogh
August and Marie Krogh on pulmonary gas exchange". Ugeskrift for Laeger. 161 (51): 7112-7116. PMID 10647306. Schmidt-Nielsen, B ... The Respiratory Exchange of Animals and Man (1916) Osmotic Regulation in Aquatic Animals (1939) The Comparative Physiology of ... He wrote his thesis on the respiration through the skin and lungs in frogs: Respiratory Exchange of Animals, 1915. Later Krogh ... Krogh, August; Weis-Fogh, Torkel (1951). "The Respiratory Exchange of the Desert Locust (Schistocerca Gregaria) before, During ...
Vagal tone
A phenomenon improving pulmonary gas exchange and circulatory efficiency". Circulation. 94 (4): 842-7. doi:10.1161/01.CIR.94.4. ... A phenomenon improving pulmonary gas exchange and circulatory efficiency". Circulation. 94 (4): 842-7. doi:10.1161/01.cir.94.4. ...
Hypoxemia
"Mechanisms of gas-exchange impairment in idiopathic pulmonary fibrosis". The American Review of Respiratory Disease. 143 (2): ... Agusti AG, Roca J, Rodriguez-Roisin R (March 1996). "Mechanisms of gas exchange impairment in patients with liver cirrhosis". ... of blood in the pulmonary circulation occurs in the bases of the pulmonary tree compared to the highest pressure of gas in the ... The partial pressures of gases increases when diving by one ATM every ten metres. This means that a partial pressure of oxygen ...
Alveolar capillary dysplasia
This results in poor gas exchange and pulmonary hypertension. There is evidence for connections between pulmonary arteries and ... Pulmonary vasodilators like sildenafil or inhaled nitric oxide can be used to reduce pulmonary blood pressures. For those with ... Another characteristic histologic finding is the presence of a pulmonary vein located next to a pulmonary artery and bronchus ... The characteristic findings of misplaced pulmonary veins adjacent to pulmonary arteries, and abnormal alveolar and capillary ...
Respiratory system
Burke, TV; Küng, M; Burki, NK (1989). "Pulmonary gas exchange during histamine-induced bronchoconstriction in asthmatic ... Insects were once believed to exchange gases with the environment continuously by the simple diffusion of gases into the ... Gas exchange in the lungs occurs in millions of small air sacs; in mammals and reptiles these are called alveoli, and in birds ... Gas exchange takes place in the gills which consist of thin or very flat filaments and lammelae which expose a very large ...
Dead space (physiology)
Burke, TV; Küng, M; Burki, NK (1989). "Pulmonary gas exchange during histamine-induced bronchoconstriction in asthmatic ... These conduct gas to the alveoli but no gas exchange occurs here. In healthy lungs where the alveolar dead space is small, ... Dead space is the volume of air that is inhaled that does not take part in the gas exchange, because it either remains in the ... This adaptation does not impact gas exchange because birds flow air through their lungs - they do not breathe in and out like ...
Exercise-induced bronchoconstriction
2008). "Pulmonary gas exchange response to exercise- and mannitol-induced bronchoconstriction in mild asthma". J Appl Physiol. ...
MYH9
Tweed WA, Phua WT, Chong KY, Lim E, Lee TL (November 1991). "Large tidal volume ventilation improves pulmonary gas exchange ...
Passive transport
"The physiological basis of pulmonary gas exchange: implications for clinical interpretation of arterial blood gases". European ... "22.4 Gas Exchange - Anatomy and Physiology , OpenStax". openstax.org. Retrieved 2020-12-06. "3.1 The Cell Membrane - Anatomy ... A biological example of diffusion is the gas exchange that occurs during respiration within the human body. Upon inhalation, ... Because the gasses are small and uncharged, they are able to pass directly through the cell membrane without any special ...
Transcellular transport
"The physiological basis of pulmonary gas exchange: implications for clinical interpretation of arterial blood gases". European ... One example of passive diffusion is the gas exchange that occurs between the oxygen in the blood and the carbon dioxide present ...
Xenon
Driehuys, B.; Möller, H.E.; Cleveland, Z.I.; Pollaro, J.; Hedlund, L.W. (2009). "Pulmonary perfusion and xenon gas exchange in ... When a patient inhales hyperpolarized xenon-129 ventilation and gas exchange in the lungs can be imaged and quantified. Unlike ... It has the lowest thermal conductivity and lowest ionization potential of all the non-radioactive noble gases. As a noble gas, ... On March 23, 1962, he mixed the two gases and produced the first known compound of a noble gas, xenon hexafluoroplatinate. ...
Inhalation exposure
Most gas exchange occurs in the pulmonary region due to the alveoli, which contain a large surface area. Scientists have ... Since the gas takes time to build up in the pulmonary region, an inhaled concentration of 600 ppm would cause a headache and ... Carbon monoxide is a relatively nonreactive gas with limited solubility. High CO levels build up in the pulmonary region over ... Once the gases are absorbed into the mucus or surfactant layer, the dissolved gases can desorb back to the air in the lungs. ...
Parenchyma
Lung parenchyma is the substance of the lung that is involved with gas exchange and includes the pulmonary alveoli. The liver ...
C. William Hanson
Marshall BE, Hanson CW, Frasch F, Marshall C: Role of HPV in pulmonary gas exchange and blood flow distribution. ... Hanson CW, Marshall BE, Frasch HF, Marshall C: The causes of hypercarbia in patients with chronic obstructive pulmonary disease ...
Discovery and development of beta2 agonists
... abnormal gas exchange and pulmonary hypertension. COPD is most common in people over fifty who have a long history of smoking. ... Smoking is the main risk factor but inhalation of toxic and harmful particles and gases can also cause the disease. The ... and long-acting β2-agonists are used to treat chronic obstructive pulmonary disease. COPD causes airflow limitations in the ... of once-daily umeclidinium/vilanterol 125/25 mcg and umeclidinium 125 mcg in patients with chronic obstructive pulmonary ...
Bronchial circulation
... and most of it through pulmonary veins. Blood reaches from the pulmonary circulation into the lungs for gas exchange to ... Bronchial arteries that carry oxygenated blood to the lungs Pulmonary capillaries, where there is exchange of water, oxygen, ... but it can still occur in pulmonary embolism when the pulmonary circulation is blocked and the bronchial circulation cannot ... Because of the dual blood supply to the lungs from both the bronchial and the pulmonary circulation, this tissue is more ...
Medipines
They are known for their device, AGM100, which provides non-invasive pulmonary gas exchange measurements in a short period of ...
Respiratory arrest
An abrupt stop of pulmonary gas exchange lasting for more than five minutes may permanently damage vital organs, especially the ... Lower airway: may occur from bronchospasm, drowning, or airspace filling disorders (e.g. pneumonia, pulmonary edema, pulmonary ... The time depends on pulse rate, pulmonary function, RBC count, and other metabolic factors. Lidocaine can be given in 1.5 mg/kg ...
List of Guggenheim Fellowships awarded in 1999
Efficient pulmonary gas exchange. Lydia Goehr, Professor of Philosophy, Columbia University: The concept of musicality in ... Tin-Lun Ho, Professor of Physics, Ohio State University: The new physics of quantum gases of alkali atoms. Robert Hooper, ...
Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus
... when the pulmonary circulation and gas exchange was proposed by Ibn Al-Nafis. Both long since proven theories are incomplete ... Moreover, the one-way valves in the heart, like those in the veins, indicate that, following the pulmonary circulation, the ...
Mammal
After gas exchange in the pulmonary capillaries (blood vessels in the lungs), oxygen-rich blood returns to the left atrium via ... Umesh KB (2011). "Pulmonary Anatomy and Physiology". Handbook of Mechanical Ventilation (1 ed.). New Delhi: Jaypee Brothers ... Levitzky MG (2013). "Mechanics of Breathing". Pulmonary physiology (8 ed.). New York: McGraw-Hill Medical. ISBN 978-0-07-179313 ... one of the four pulmonary veins. Blood flows nearly continuously back into the atrium, which acts as the receiving chamber, and ...
Gas exchange
... pulmonary alveoli and spongy mesophyll provide the large area needed for effective gas exchange. These convoluted surfaces may ... Plant gas exchange occurs mostly through the leaves. Gas exchange between a leaf and the atmosphere occurs simultaneously ... These air sacs do not play a direct role in gas exchange, but help to move air unidirectionally across the gas exchange ... typically perform gas exchange with a book lung. Respiratory system - Biological system in animals and plants for gas exchange ...
Alveolar gas equation
Raymond L, Dolan W, Dutton R, et al: Pulmonary function and gas exchange during altitude hypoxia (abstract). Clin Res 19:147, ... in the inspired gas are in equilibrium with their dissolved states in the blood Inspired and alveolar gases obey the ideal gas ... The equation relies on the following assumptions: Inspired gas contains no carbon dioxide (CO2) Nitrogen (and any other gases ... Pulmonary gas pressures Curran-Everett D (June 2006). "A classic learning opportunity from Fenn, Rahn, and Otis (1946): the ...
Breath gas analysis
... related to both the breath sampling protocols as well as the complex physiological mechanisms underlying pulmonary gas exchange ... Gas chromatography-mass spectrometry GC-MS Gas chromatography-UV spectrometry GC-UV Proton transfer reaction mass spectrometry ... Breath gas analysis is used in a number of breath tests. Asthma detection by exhaled nitric oxide Blood alcohol testing Carbon ... Breath gas analysis is a method for gaining information on the clinical state of an individual by monitoring volatile organic ...
List of MeSH codes (G09)
... pulmonary gas exchange MeSH G09.772.770.820 - sneezing MeSH G09.772.770.980 - yawning The list continues at List of MeSH codes ... pulmonary diffusing capacity MeSH G09.772.765.650 - pulmonary ventilation MeSH G09.772.765.650.300 - forced expiratory flow ... pulmonary circulation MeSH G09.330.582.163.780 - regional blood flow MeSH G09.330.582.163.812 - renal circulation MeSH G09.330. ... pulmonary wedge pressure MeSH G09.330.553.400.114.732 - venous pressure MeSH G09.330.553.400.114.732.336 - central venous ...
Phosgene
It was a highly potent pulmonary irritant and quickly filled enemy trenches due to it being a heavy gas. It is classified as a ... the site of gas exchange), respectively forming ester, amide and thioester functional groups in accord with the reactions ... Gas weapons, such as phosgene, were produced by Unit 731. Phosgene is an insidious poison as the odor may not be noticed and ... It is a toxic, colorless gas; in low concentrations, its musty odor resembles that of freshly cut hay or grass. Phosgene is a ...
List of MeSH codes (E01)
... pulmonary gas exchange MeSH E01.370.386.700.650.650 - pulmonary diffusing capacity MeSH E01.370.386.700.650.900 - ventilation- ... blood gas analysis MeSH E01.370.386.700.100.600 - oximetry MeSH E01.370.386.700.100.600.100 - blood gas monitoring, ... blood gas analysis MeSH E01.450.150.100.100.600 - oximetry MeSH E01.450.150.100.100.600.100 - blood gas monitoring, ... blood gas monitoring, transcutaneous MeSH E01.370.370.380.650 - pulse MeSH E01.370.370.380.710 - radionuclide ventriculography ...
Altitude sickness
... and prevents further impairment of pulmonary gas exchange." The folk remedy for altitude sickness in Ecuador, Peru and Bolivia ... impaired gas exchange, fluid retention or increased sympathetic drive. There is thought to be an increase in cerebral venous ... clinical efficacy and effect on gas exchange". Annals of Internal Medicine. 116 (6): 461-5. doi:10.7326/0003-4819-116-6-461. ... Oxygen from gas bottles or liquid containers can be applied directly via a nasal cannula or mask. Oxygen concentrators based ...
List of MeSH codes (G06)
... pulmonary gas exchange MeSH G06.535.166.850 - rna transport MeSH G06.535.256.249 - fermentation MeSH G06.535.256.500 - ...
Liquid breathing
Aerosolized perfluorocarbon improved pulmonary gas exchange and lung mechanics as effectively as PLV did in surfactant-depleted ... gas exchange can occur. This requires certain physical properties such as respiratory gas solubility, density, viscosity, vapor ... Matthews, W. H.; Balzer, R. H.; Shelburne, J. D.; Pratt, P. C.; Kylstra, J. A. (Dec 1978). "Steady-state gas exchange in ... A significant positive step was the use of PFC-associated gas exchange, now termed partial liquid ventilation (PLV). Hirschl, ...
Diving bell
A gas panel inside the bell is supplied by the bell umbilical and the emergency gas cylinders, and supplies the divers' ... North of Boston Library Exchange. pp. 67-68. Retrieved 24 June 2020.. ... The emergency gas supply (EGS) is connected via manifolds to the internal gas panel. The part of the framework that keeps the ... Adding pressurized gas ensures that the gas space within the bell remains at constant volume as the bell descends in the water ...
COVID-19 - Simple English Wikipedia, the free encyclopedia
One cell, type I, absorbs from the air, i.e. gas exchange. The other, type II, produces surfactants, which help keep the lungs ... Fluids, pus, and dead cell material flood the lung, causing the coronavirus pulmonary disease.[17] ... The expanding part of the lungs, pulmonary alveoli, have two main types of cells. ... pulmonary fibrosis, pediatric multisystem inflammatory syndrome, chronic COVID syndrome. ...
Electrical impedance tomography
... gas exchange, and histological signs of ventilator-associated lung injury.[47]. In addition to visual information (e.g. ... The high temporal resolution of EIT allows regional assessment of common dynamic parameters used in pulmonary function testing ... changes of intrathoracal gas volume during critical illness) - however, such parameters still require careful evaluation and ... or the movement of fluids and gases within tissues (difference EIT). The majority of EIT systems apply small alternating ...
Organ-on-a-chip
... gas and liquid exchange, as well as an ease of observation via conventional microscopy.[70] ... Pulmonary inflammation Pulmonary inflammatory responses entail a multistep strategy, but alongside an increased production of ... Pulmonary infection. Living E-coli bacteria was used to demonstrate how the system can even mimic the innate cellular response ... By investigating the pulmonary response to nanoparticles, researchers hope to learn more about health risks in certain ...
Breathing - Simple English Wikipedia, the free encyclopedia
Gas exchange in humans. Oxygen and carbon dioxide switch places between a capillary (part of the bloodstream) and an alveolus ( ... "Pulmonary Advanced Physical Diagnosis: Physiology". Loyola University Medical Education Network. Loyola University Chicago. ... This is called gas exchange: basically, oxygen and carbon dioxide are changing places. Oxygen is now in the bloodstream, which ... "Exchanging Oxygen and Carbon Dioxide". Merck Manual. Merck & Co., Inc. Retrieved January 29, 2016.. {{cite web}}. : CS1 maint: ...
Carbon nanotube
Using carbon nanotubes for environmental monitoring due to their active surface area and their ability to absorb gases.[116] ... CNT-based yarns are suitable for applications in energy and electrochemical water treatment when coated with an ion-exchange ... It must be noted that although CNT caused pulmonary inflammation and toxicity in mice, exposure to aerosols generated from ... Nikolaev P (April 2004). "Gas-phase production of single-walled carbon nanotubes from carbon monoxide: a review of the hipco ...
Pulmonary agenesis
Hence, the affected areas lose their function of gas exchange. This malformation is thought to involve the proliferation arrest ... Pulmonary angiography assists in detecting the presence of pulmonary artery branches, differentiating pulmonary agenesis to ... Verwey, Charl; Van der Merwe, Cornelis; Pillay, Tanyia (April 28, 2017). "Pulmonary agenesis, pulmonary aplasia and pulmonary ... pulmonary agenesis and aplasia differ from pulmonary hypoplasia in their underlying cause. Unlike pulmonary hypoplasia which in ...
Atretochoana
... and an absence of pulmonary arteries. Its skin is filled with capillaries that penetrate the epidermis, allowing gas exchange. ...
Blood-air barrier
The blood-air barrier or air-blood barrier, (alveolar-capillary barrier or membrane) exists in the gas exchanging region of the ... This can be a result of several possible causes, including blast injury, swimming-induced pulmonary edema, and breathing gas ... The barrier is permeable to molecular oxygen, carbon dioxide, carbon monoxide and many other gases. This blood-air barrier is ... Possible consequences of rupture of the blood-air barrier include arterial gas embolism and hemoptysis. Blood-brain barrier - ...
Coal in Turkey
Flue gas emission limits are in place, but data from mandatory reporting is not made public. As the Ottoman Navy expanded its ... Coal miners suffer respiratory diseases such as black lung, chronic obstructive pulmonary disease, back pain, periodontal ... the producer price index and the dollar exchange rate, and paid by the state-owned electricity company to private-sector power ... Imports of natural gas started in the late 1980s and by the end of the 2010s the pipeline distribution network had been ...
List of unsolved deaths
A 2006 TV documentary suggested their deaths were not due to foul play but the result of hydrogen sulfide gas leaking from the ... Cecil Kern (41-45), female American theater director and stage and film actress who was reported to have died of a pulmonary ... and singer who came to prominence for her appearances in several Pathé Exchange and Universal Pictures films in the 1920s who ...
Pneumonitis
Azathioprine and mycophenolate are two particular treatments that have been associated with an improvement of gas exchange. ... Some degree of pulmonary fibrosis may be evident in a CT which is indicative of chronic pulmonary inflammatory processes. ... "Evaluation of the Pulmonary Patient - Pulmonary Disorders". Merck Manuals Professional Edition. Retrieved 2020-03-26. " ... "Hypersensitivity Pneumonitis - Pulmonary Disorders". Merck Manuals Professional Edition. Retrieved 2020-03-26. Keffer S, Guy CL ...
Harold Zirin
In 1960-1961, in perhaps the first exchange with the U.S. that the Soviet Union permitted outside major Soviet cities, Harold ... or apparent surface of roiling gases) could rise to over a million degrees in the corona (the apparent atmosphere above the ... Harold and Mary Zirin provided funding to National Jewish Health in 2005 for an Endowed Chair in Pulmonary Biology. Harold died ...
Per- and polyfluoroalkyl substances
The water becomes supercritical (being neither gas nor liquid), and, in this state, water-repellent substances such as PFASs ... Exposure to aerosolized PFASs is associated with alveolic edema, polymer fume fever, severe dyspnea, decreased pulmonary ... The technologies are: Sorption Granular activated carbon Biochar Ion exchange Precipitation/flocculation/coagulation Redox ...
Phosphine
Exposure results in pulmonary edema (the lungs fill with fluid). Phosphine gas is heavier than air so it stays near the floor. ... Proton exchange proceeds via a phosphonium (PH+4) ion in acidic solutions and via phosphanide (PH−2) at high pH, with ... MATERIAL SAFETY DATA SHEET: PHOSPHINE/HYDROGEN GAS MIXTURE (PDF) (Report). Matheson TRI-GAS, inc. 8 September 2008. Rabinowitz ... "Mémoire sur un nouveau gas obtenu, par l'action des substances alkalines, sur le phosphore de Kunckel" (Memoir on a new gas ...
Shortness of breath
Thus, poor ventilation leading to hypercapnia, left heart failure leading to interstitial edema (impairing gas exchange), ... or a large pulmonary embolism. A chest x-ray is useful to confirm or rule out a pneumothorax, pulmonary edema, or pneumonia. ... pulmonary embolism, or pneumothorax. Patients with COPD and idiopathic pulmonary fibrosis (IPF) have a mild onset and gradual ... D-dimer, while useful to rule out a pulmonary embolism in those who are at low risk, is not of much value if it is positive, as ...
Acute inhalation injury
Hlastala MP, Ralph DD, Babb AL, Influence of gas physical properties on pulmonary gas exchange, Adv Exp Med Biol. 227 (1988) 33 ... Gas exchange is affected by increases in the dispersion of both alveolar ventilation and cardiac output because bronchial and ... 2007) Breath tests and airway gas exchange. Pulm Pharmacol Ther. 20:112-7. Luh SP, Chiang CH. (2007) Acute lung injury/acute ... Respiratory damage is related to the concentration of the gas and its solubility. Irritant gas exposures predominantly affect ...
World War I prisoners of war in Germany
... and in 1916 2,970 French medical staff were exchanged for 1,150 German medical staff. The Allies made similar exchanges with ... 25 years old, not a sou in my pocket, my health weakened by poison gas, bronchitis… In sum, I was disgusted by life". ... The humid forts requisitioned to serve as places of detention led to numerous cases of pulmonary illness. The German ... At the end of the war, the Red Cross took part in prisoners' repatriation, but it also helped initiate prisoner exchanges and ...
Biofluid dynamics
The process of gas exchange, that is, exchange of carbon dioxide with oxygen in the lungs is the main function of the pulmonary ... The tricuspid valve, right heart (right ventricle), pulmonary valve, pulmonary artery, lungs, pulmonary veins and right heart ... which is the main carrier of oxygen in the blood are responsible for this exchange of gases before they are carried to the left ... The pulmonary circulation system consists of the network of blood vessels from the right heart to the lungs and back to the ...
Altitude
Air is a poor conductor of heat, so a parcel of air will rise and fall without exchanging heat. This is known as an adiabatic ... If radiation were the only way to transfer heat from the ground to space, the greenhouse effect of gases in the atmosphere ... high altitude pulmonary edema, and high altitude cerebral edema. The higher the altitude, the more likely are serious effects. ... Parties exchanging altitude information must be clear which definition is being used. Aviation altitude is measured using ...
Pulmonary alveolus
... with gas exchange taking place in all the alveoli present. The alveolar membrane is the gas exchange surface, surrounded by a ... This leads to a smaller volume of gas exchanged per breath. Pulmonary alveolar microlithiasis is a rare lung disorder of small ... impairing gas exchange . Pulmonary edema is the buildup of fluid in the parenchyma and alveoli usually caused by left ... This thin lining enables a fast diffusion of gas exchange between the air in the alveoli and the blood in the surrounding ...
Influenza
In particular, alveolar cell infection appears to drive severe symptoms since this results in impaired gas exchange and enables ... Fatigue and malaise may last for several weeks after recovery, and healthy adults may experience pulmonary abnormalities that ... Guerra F (1993). "The European-American exchange". Hist Philos Life Sci. 15 (3): 313-327. PMID 7529930. Institute of Medicine ( ... such as chronic obstructive pulmonary disease or asthma exacerbation, since they are associated with increased mortality. If a ...
Emergency department
7 March 2022). "Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension". Pulmonary ... Busy EDs exchange a great deal of equipment with ambulance crews, and both must provide for replacing, returning, or ... have an urgent chest X-ray and arterial blood gases and are referred for intensive care if necessary. Noninvasive ventilation ... Health information exchanges can reduce nonurgent ED visits by supplying current data about admissions, discharges, and ...
January 1923
The value of the German papiermark fell to less than 1/40,000th of a U.S. dollar for the first time on currency exchanges, ... A mine explosion and toxic gas killed 145 coal miners at the German-owned Heinitz Coal Company operating in Rozbark, near Bytom ... Katherine Mansfield, 34, New Zealand-born short fiction writer, from pulmonary tuberculosis Satyendranath Tagore, 81, Indian ... Ratifications were exchanged Treaty of Rapallo between Germany and Soviet Russia, soon to be extended to the other member ...
Lithium
The metal reacts with hydrogen gas at high temperatures to produce lithium hydride (LiH). Lithium forms a variety of binary and ... and ion exchange. Lithium ions substitute for magnesium and iron in octahedral sites in clay minerals, where 6Li is preferred ... leading to pulmonary edema. The metal itself is a handling hazard because contact with moisture produces the caustic lithium ... The reaction forms hydrogen gas and lithium hydroxide. When placed over a flame, lithium compounds give off a striking crimson ...
Epithelial sodium channel
... interfering with gas exchange and allowing for the collection of bacteria. Nevertheless, an upregulation of CFTR does not ... In addition to being implicated in diseases where fluid balance across epithelial membranes is perturbed, including pulmonary ...
Ozone
Gases, Greenhouse gases, Industrial gases, Oxidizing agents, Homonuclear triatomic molecules, Gases with color, Pollution, Air ... Al-Hegelan, M.; Tighe, R. M.; Castillo, C.; Hollingsworth, J. W. (2011). "Ambient ozone and pulmonary innate immunity". Immunol ... H2O NaO3 and LiO3 must be prepared by action of CsO3 in liquid NH3 on an ion-exchange resin containing Na+ or Li+ ions: CsO3 + ... The gas was applied directly to wounds for as long as 15 minutes. This resulted in damage to both bacterial cells and human ...
Tetrapod
Amphibians must return to water to lay eggs; in contrast, amniote eggs have a membrane ensuring gas exchange out of water and ... Lungs and swim bladders are homologous (descended from a common ancestral form) as is the case for the pulmonary artery (which ... In some animals waterproof barriers impede the exchange of gases through the skin. For example, keratin in human skin, the ... and modern proteinaceous fish scales impede the exchange of gases. However, early tetrapods had scales made of highly ...
Trichomonas
It is an opportunistic pathogen and may cause pulmonary trichomoniasis. Trichomonas in birds inhabit the upper digestive tract ... Trichomonas tenax is transmitted through exchange of saliva and contaminated water sources. ... generating hydrogen gas as a by-product. Trichomonas vaginalis, being the species that causes the most complications in humans ... Hersh, S. M. (1 August 1985). "Pulmonary trichomoniasis and Trichomonas tenax". Journal of Medical Microbiology. 20 (1): 1-10. ...
Oxygen Pulmonary Gas Exchange | Pathway Medicine
As a result, heavy exercise pushes pulmonary gas exchange to the cusp of switching from perfusion-limitation to diffusion- ... Given these features, it is clear that oxygen gas exchange is perfusion-limited in a normal, healthy lung. However, a number of ... Certain pulmonary disease result in pathological thickening of the alveolar membrane which in turn can substantially reduce the ... In such a scenario, oxygen gas is rendered diffusion-limited and results in reductions in the partial pressure of arterial ...
Carbon Dioxide Pulmonary Gas Exchange | Pathway Medicine
Consequently, pulmonary gas exchange of carbon dioxide is perfusion-limited. It appears that few physiological or pathological ... Pulmonary Gas Exchange - Basic Principles. *Oxygen Pulmonary Gas Exchange. *Carbon Dioxide Pulmonary Gas Exchange ... early in its course through the pulmonary capillaries. In other words, the partial pressure gradient of carbon dioxide across ... the alveolar membrane is eliminated early on as blood moves through the pulmonary capillaries. ...
August Krogh - Wikipedia
August and Marie Krogh on pulmonary gas exchange". Ugeskrift for Laeger. 161 (51): 7112-7116. PMID 10647306. Schmidt-Nielsen, B ... The Respiratory Exchange of Animals and Man (1916) Osmotic Regulation in Aquatic Animals (1939) The Comparative Physiology of ... He wrote his thesis on the respiration through the skin and lungs in frogs: Respiratory Exchange of Animals, 1915. Later Krogh ... Krogh, August; Weis-Fogh, Torkel (1951). "The Respiratory Exchange of the Desert Locust (Schistocerca Gregaria) before, During ...
Effect of edentulism on spirometric tests
Gas exchange response to Naloxone in chronic obstructive pulmonary disease with hypercap¬nic respiratory failure<...
Gas exchange response to Naloxone in chronic obstructive pulmonary disease with hypercap¬nic respiratory failure. In: Bull Eur ... 1987). Gas exchange response to Naloxone in chronic obstructive pulmonary disease with hypercap¬nic respiratory failure. Bull ... Gas exchange response to Naloxone in chronic obstructive pulmonary disease with hypercap¬nic respiratory failure. Bull Eur ... Gas exchange response to Naloxone in chronic obstructive pulmonary disease with hypercap¬nic respiratory failure. / Roca, J; ...
Beryllium Toxicity: Clinical Assessment - Other Diagnostic Tests | Environmental Medicine | ATSDR
Repeat pulmonary function and gas exchange tests. The most sensitive physiologic test for the detection of CBD is the ... including pulmonary function tests, measurement of DLCO, and exercise capacity testing (preferably with an arterial blood gas ... and the remainder have a mixed pattern of obstruction and restriction with varying amounts of gas exchange abnormality (Newman ... The exercise capacity test reveals gas exchange or ventilatory abnormalities, including an elevation in the dead space-to-tidal ...
On issues of confidence in determining the time constant for oxygen uptake kinetics | British Journal of Sports Medicine
Whipp BJ, Mahler M. Dynamics of pulmonary gas exchange during exercise. In: West JB, ed. Pulmonary gas exchange. New York: New ... We chose a work rate that we felt would be below the subjects gas exchange threshold based on gas exchange indices described ... Effects of prior exercise on pulmonary gas-exchange kinetics during high-intensity exercise in humans. J Appl Physiol1996;80:99 ... Karlsson H , Lindborg B, Linnarsson D. Time courses of pulmonary gas exchange and heart rate changes in supine exercise. Acta ...
Selective Pulmonary Vasodilation Induced by Aerosolized Zaprinast | Anesthesiology | American Society of Anesthesiologists
Effects of Intravenous Zaprinast and Inhaled Nitric Oxide on Pulmonary Hemodynamics and Gas Exchange in an Ovine Model of Acute ... 20]Inhaled NO improves pulmonary gas exchange in patients with acute respiratory distress syndrome. [22]Although inhaled ... Will Combining Intravenous Zaprinast with Inhaled NO Improve Gas Exchange in ARDS? Adrie et al. (page 422) Anesthesiology ( ... Sildenafil Is a Pulmonary Vasodilator in Awake Lambs with Acute Pulmonary Hypertension Anesthesiology (June 2000) ...
Deep Vein Thrombosis and Pulmonary Embolism in the Operating Room: Practice Essentials, Problem, Management
Contribution of multiple inert gas elimination technique to pulmonary medicine--4. Gas exchange abnormalities in pulmonary ... Emergency TEE was performed and showed a large pulmonary embolus in the pulmonary trunk and the right and left pulmonary ... which shows a large embolus in the pulmonary trunk (pulmonary artery) and in both the right and the left pulmonary artery (see ... Deep Vein Thrombosis and Pulmonary Embolism in the Operating Room * Sections Deep Vein Thrombosis and Pulmonary Embolism in the ...
Idiopathic Pulmonary Fibrosis Imaging: Practice Essentials, Radiography, Computed Tomography
... is a chronic progressive pulmonary disease of unknown etiology. It is primarily diagnosed on the basis of clinical, physiologic ... and physiologic evidence of restriction and impaired gas exchange on pulmonary function testing. ... How is idiopathic pulmonary fibrosis (IPF) diagnosed?. What is the role of radiography in the workup of idiopathic pulmonary ... Pulmonary artery size as a predictor of outcomes in idiopathic pulmonary fibrosis. Eur Respir J. 2016 May. 47 (5):1445-51. [ ...
Pulmonary agenesis - Wikipedia
Hence, the affected areas lose their function of gas exchange. This malformation is thought to involve the proliferation arrest ... Pulmonary angiography assists in detecting the presence of pulmonary artery branches, differentiating pulmonary agenesis to ... Verwey, Charl; Van der Merwe, Cornelis; Pillay, Tanyia (April 28, 2017). "Pulmonary agenesis, pulmonary aplasia and pulmonary ... pulmonary agenesis and aplasia differ from pulmonary hypoplasia in their underlying cause. Unlike pulmonary hypoplasia which in ...
Hyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease | Clinical...
Hyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease ... pulmonary hypertension) and provide new insights regarding the normal resting heterogeneity of pulmonary gas exchange. ... Such imaging of 129Xe gas transfer is expected to be uniquely sensitive to pathologies affecting gas exchange (fibrosis, ... and regional gas exchange. Because 129Xe MRI uses no ionizing radiation, and only an inhaled gas contrast agent, it has the ...
Electrical Injuries - Injuries; Poisoning - Merck Manuals Professional Edition
SciELO - Brazil - Computed tomography assessment of lung structure in patients undergoing cardiac surgery with cardiopulmonary...
Gas exchange impairment and pulmonary densities after cardiac surgery. Acta Anaesthesiol Scand 1992; 36: 800-805. ... Gas exchange impairment and pulmonary densities after cardiac surgery. Acta Anaesthesiol Scand 1992; 36: 800-805. ... Hypoxaemia after cardiac surgery: clinical application of a model of pulmonary gas exchange. Eur J Anaesthesiol 2004; 21: 296- ... Hypoxaemia after cardiac surgery: clinical application of a model of pulmonary gas exchange. Eur J Anaesthesiol 2004; 21: 296- ...
Shock in Pediatrics Medication: Inotropic agents, Phosphodiesterase Enzyme Inhibitor, Prostaglandins, Endocrine, Corticosteroid
Continuous arteriovenous hemofiltration/dialysis improves pulmonary gas exchange in children with multiple organ system failure ... Exchange transfusion in the treatment of neonatal septic shock: a ten-year experience in a neonatal intensive care unit. Int J ... This agent is beneficial in infants with congenital defects that restrict pulmonary or systemic blood flow and in patients who ... Bassler D, Kreutzer K, McNamara P, Kirpalani H. Milrinone for persistent pulmonary hypertension of the newborn. Cochrane ...
Role of the Domestic Chicken (Gallus gallus)in the Epidemiology of Urban Visceral Leishmaniasis in Brazil - Volume 8, Number 12...
CRSNG - R sultats des concours de subventions de recherche par universit - 2022
Inspiratory muscle warm-up does not improve cycling time-trial performance<...
... pulmonary gas exchange, heart rate, blood lactate concentration and pH) and perceptual (limb discomfort and dyspnoea) responses ... pulmonary gas exchange, heart rate, blood lactate concentration and pH) and perceptual (limb discomfort and dyspnoea) responses ... pulmonary gas exchange, heart rate, blood lactate concentration and pH) and perceptual (limb discomfort and dyspnoea) responses ... pulmonary gas exchange, heart rate, blood lactate concentration and pH) and perceptual (limb discomfort and dyspnoea) responses ...
CARDIOVASCULAR SYSTEM | MindMeister Mind Map
Pulmonary Gas Exchange and Transport: Its purpose is to purify O2 by exchanging the metabolic waste of the Krebs Cycle: CO2; ... Gas Transport: IMPORTANT. 12.1.1. alveoli and capillaries exchange and blood at alveolar capillary interface because those ... Exchange vessels: walls consist of a single layer of endothelium, smallest of blood vessels where physical exchange occurs ... 5: From the lungs, oxygenated blood comes back to the heart through the pulmonary vien. 4.6. From the pulmonary vein, blood ...
Dr. Robert Trampel | Max Planck Institute for Human Cognitive and Brain Sciences
Evaluation of inhaled nitric oxide (iNO) treatment for moderate-to-severe ARDS in critically ill patients with COVID-19: a...
Rodriguez-Roisin R. Pulmonary gas exchange in acute respiratory failure. Eur J Anaesthesiol. 1994;11:5-13. ... In this study, the gas sampling line was attached to the back of the analyzer, and then the gas sampling line was attached to ... Nitric oxide emanates in gas form and is stored in cylinders. The gas regulator should be attached to the nitric oxide (NO) ... Acute pulmonary hypertension and short-term outcomes in severe Covid-19 patients needing intensive care. Acta Anaesthesiol ...
Ralf BENSBERG | Doctor of Medicine | RWTH Aachen University, Aachen | Faculty of Medicine and University Hospital
Partial ventilatory support can effectively unload the respiratory workload and improve pulmonary gas exchange with less ... Veno-venous extracorporeal lung assist (ECLA) can provide sufficient gas exchange even in most severe cases of acute ... Influence of elevated abdominal pressure (EAP) on lung mechanics and gas exchange during PCV with and without spontaneous ... Extracorporeal membrane oxygenation can achieve sufficient gas exchange in severe acute respiratory distress syndrome. A highly ...
Rochester, MN - Research output - Mayo Clinic
Wegeners granulomatosis and pulmonary vasculitis. Specks, U., Jan 1 1995, In: Clinical Pulmonary Medicine. 2, 5, p. 267-275 9 ... Edell, E. S., Jul 1995, In: Current opinion in pulmonary medicine. 1, 4, p. 248-252 5 p.. Research output: Contribution to ... Pulmonary manifestations of nontuberculous Mycobacterium. Patz, E. F., Swensen, S. J. & Erasmus, J., Jan 1 1995, In: Radiologic ...
Effect of Ischemic Preconditioning on Endurance Performance... : Medicine & Science in Sports & Exercise
Pulmonary ventilation and gas exchange were filtered to exclude aberrant breaths (two standard deviations from the mean of a 15 ... Ventilation and pulmonary gas exchange were recorded breath by breath throughout the exercise tests using a metabolic analyzer ... Due to technical problems, the sample size for peak ventilation, peak pulmonary gas exchange, and peak HR were reduced to 16. ... pulmonary ventilation and gas exchange, blood lactate concentration, and perceived effort were measured during a discontinuous ...
Hyperventilation - Ontology Report - Rat Genome Database
Gordon Prisk | UCSD Profiles
Noninvasive measurement of pulmonary gas exchange: comparison with data from arterial blood gases. Am J Physiol Lung Cell Mol ... Measurements of pulmonary gas exchange efficiency using expired gas and oximetry: results in normal subjects. Am J Physiol Lung ... Measuring the efficiency of pulmonary gas exchange using expired gas instead of arterial blood: comparing the "ideal" Po2 of ... A new method for noninvasive measurement of pulmonary gas exchange using expired gas. Respir Physiol Neurobiol. 2018 01; 247: ...
NIOSHTIC-2 Search Results - Full View
Fibrous thickening of the alveolar septa decreases the lungs capacity for gas exchange. Pulmonary macrophage damage by ... We have observed that exposing respirable sized native silica or kaolin for two hours to pulmonary macrophages results in a ... The release of three enzymes from pulmonary macrophages were used as indicators of cell death or damage following dust exposure ... However, the ability of these assays to predict the pulmonary disease producing potential of various dusts is imperfect owing ...
Istituto di Analisi dei Sistemi ed Informatica "Antonio Ruberti" (Publications)
Publications | Clinical Exercise & Respiratory Physiology Laboratory - McGill University
Pulmonary gas exchange abnormalities in mild chronic obstructive pulmonary disease: Implications for exercise tolerance. ... Effects of human pregnancy and aerobic conditioning on alveolar gas exchange during exercise. Canadian Journal of Physiology ... Exertional dyspnea in chronic obstructive pulmonary disease: mechanisms and treatment approaches. Current Opinion in Pulmonary ... Impact of pulmonary emphysema on exercise capacity and its physiological determinants in chronic obstructive pulmonary disease ...
VentilationIdiopathicCOPDPhysiologyHypertensionArteryEdemaEmbolismAlveoliInterstitialCapillariesPostoperative pulmonaryPerfusionEmphysemaOxygenationComplicationsVasculatureDiseasesArterial pressureAirwayHypoxic Pulmonary Vasoco2022ObstructiveVascular diseaseCritical Care MedShortness of breHypoxemiaPathophysiologyFunctionTissueDiseaseDisordersPhysiologicalPatientsOxygen and carbon dioxideHAPEChanges in pulmonaryPatient'sSymptomsInduce pulmonaryCommon pulmonaryImpairmentMechanicsCarbonToxicitySystemicArteriesHypoxiaInhalationClinicalLungs for gas exchangeIntravenousAcute respirat
Ventilation19
- While the maintenance of ventilation/perfusion ratio during regional obstruction of airflow is beneficial, HPV can be detrimental during global alveolar hypoxia which occurs with exposure to high altitude, where HPV causes a significant increase in total pulmonary vascular resistance, and pulmonary arterial pressure, potentially leading to pulmonary hypertension and pulmonary edema. (wikipedia.org)
- Specifically, three forms of 129Xe MRI contrast will be the investigators focus - 1) imaging of the 129Xe ventilation distribution, 2) imaging the alveolar microstructure via the 129Xe apparent diffusion coefficient (ADC), and 3) imaging 129Xe that dissolves in the pulmonary blood and tissues upon inhalation. (centerwatch.com)
- We have recently shown HP 129Xe MRI to visualize pulmonary ventilation with high resolution, as well as the ability to show abnormalities of the alveolar microstructure that are associated with the emphysema phenotype of COPD. (centerwatch.com)
- Moreover, the properties of 129Xe enable images to be acquired with multiple forms of contrast including ventilation, lung microstructure, and regional gas exchange. (centerwatch.com)
- Throughout the time-trial, physiological (minute ventilation, breathing pattern, pulmonary gas exchange, heart rate, blood lactate concentration and pH) and perceptual (limb discomfort and dyspnoea) responses were not different between CYC and CYC + IMW. (bath.ac.uk)
- ARDS can cause an imbalance between ventilation and perfusion, resulting in intensified intrapulmonary shunting in nonventilated lung regions from pulmonary vasodilation and vasoconstriction in ventilated zones, as well as pulmonary hypertension [ 12 ]. (biomedcentral.com)
- Inhaled nitric oxide may improve ventilation and overcome perfusion imbalance and pulmonary vascular resistance, relieving hypoxemia caused by ARDS [ 14 ]. (biomedcentral.com)
- Next, pulmonary ventilation and gas exchange, blood lactate concentration, and perceived effort were measured during a discontinuous incremental test on a treadmill. (lww.com)
- A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. (mcw.edu)
- We describe the second reported case of successful utilization of mechanical ventilation and extracorporeal membrane oxygenation (ECMO) in order to treat acute pulmonary toxicity caused by SC inhalation by a water pipe. (scirp.org)
- Pulmonary ventilation and circulation. (unica.it)
- In this study, we tested the hypothesis that the topical use of a NF-κB inhibitor (IκB kinase-NF-κB essential modulator binding domain [IKK-NBD] peptide), together with surfactant as a carrier substance, improves surfactant function by attenuation of pulmonary inflammation during 24 hrs of mechanical ventilation in a neonatal piglet model of acute respiratory distress syndrome by repeated airway lavage. (eur.nl)
- CONCLUSION: Supplementation of exogenous surfactant with a NF-κB inhibitor to create a "fortified" surfactant improves gas exchange, lung function, and pulmonary edema during 24 hrs of mechanical ventilation, without a secondary functional relapse. (eur.nl)
- However, OLV can result in severe hypoxemia, requiring a mechanical ventilation approach that is able to maintain adequate gas exchange, while protecting the lungs against postoperative pulmonary complications (PPCs). (forschung-sachsen-anhalt.de)
- HPV causes pulmonary arterial vessels to constrict in response to local hypoxia, redistributing blood flow away from poorly ventilated regions and toward lung regions that are well ventilated, optimizing local ventilation/perfusion matching and minimizing shunt fraction (Qs/Qt). (silverchair.com)
- The goal is enhance secretion clearance to help prevent lung infections, enhance ventilation, improve pulmonary function and gas exchange. (blogspot.com)
- Ventilation is the exchange of air between the atmosphere and the alveoli. (biologyonline.com)
- It is uncertain whether assisted lung ventilation versus pressure control-volume guaranteed ventilation reduces ventilation-induced pulmonary injury and inflammation during anaesthesia for robotic surgery. (intensive-care.ru)
- Moreover, there is no single functional predictor of progression in CF, but aside from risk factors, such as onset of chronic P. aeruginosa infection and genotype, pulmonary hyperinflation, airway obstruction, and ventilation inhomogeneities are important pathophysiologic processes that should be evaluated concomitantly as determinants of lung progression in CF. (nih.gov)
Idiopathic15
- Idiopathic pulmonary fibrosis (IPF) is a form of idiopathic interstitial pneumonia, associated a median survival of 2-5 years from the time of diagnosis. (medscape.com)
- It has been postulated that sildenafil, a phosphodiesterase-5 inhibitor and pulmonary artery vasodilator, may improve gas exchange in advanced idiopathic pulmonary fibrosis by preferentially increasing perfusion to well-ventilated areas of lung. (bmj.com)
- The authors conclude that the therapeutic efficacy of sildenafil in advanced idiopathic pulmonary fibrosis remains uncertain and that further trials are necessary. (bmj.com)
- the Idiopathic Pulmonary Fibrosis Clinical Research Network. (bmj.com)
- A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis. (bmj.com)
- Idiopathic Pulmonary Fibrosis (IPF) , also known as Cryptogenic fibrosing alveolitis , is a chronic progressive interstitial lung disease of unknown etiology. (bionity.com)
- [3] Autoantibodies, a hallmark of autoimmune diseases, are found in a minority of patients with truly idiopathic pulmonary fibrosis. (bionity.com)
- Idiopathic pulmonary fibrosis is a type of idiopathic interstitial pneumonia (IIP), which in turn is a type (or group) of interstitial lung diseases . (bionity.com)
- Idiopathic Pulmonary Fibrosis is slightly more common in males and usually presents in patients greater than 50 years of age. (bionity.com)
- Idiopathic pulmonary fibrosis (IPF) is a progressive and generally fatal disease characterized by scarring of the lungs that thickens the lining of the lungs, causing an irreversible loss of the tissue's ability to transport oxygen. (every1dies.org)
- Stevan, who was diagnosed with idiopathic pulmonary fibrosis and had a double lung transplant five years ago, shares his philosophy about living with chronic illness. (every1dies.org)
- At other times this fibrosis of the lungs (fiber build-up) is of unknown cause and therefore termed idiopathic pulmonary fibrosis. (earthclinic.com)
- Idiopathic Pulmonary Fibrosis: My husband was on Esbriet and had horrible side effects. (earthclinic.com)
- By integrated multiscale biomechanical and biological analyses of idiopathic pulmonary fibrosis lung tissue, we identify that increased tissue stiffness is a function of dysregulated post-translational collagen cross-linking rather than any collagen concentration increase whilst at the nanometre-scale collagen fibrils are structurally and functionally abnormal with increased stiffness, reduced swelling ratio, and reduced diameter. (elifesciences.org)
- Idiopathic pulmonary fibrosis (IPF) is a devastating disease of the lung, which scars the tissue and gradually destroys the organ, ultimately leading to death. (elifesciences.org)
COPD14
- We compared the values of FVC, FEV(1), PEFR, FEF(50%), FIV(1), and FIF(50%) recorded with and without dentures in three groups of edentulous subjects: 36 asymptomatic subjects with normal spirometry (N), 22 patients with chronic obstructive pulmonary disease (COPD), and 18 with interstitial lung disease (ILD). (nih.gov)
- COPD: Journal of Chronic Obstructive Pulmonary Disease. (mcgill.ca)
- In this guide to hypercapnia (also known as hypercarbia), we will discuss the hypercapnia definition and how the condition relates to chronic obstructive pulmonary disease (COPD), as well as hypercapnia causes, symptoms, treatments, and what exactly high carbon dioxide in the blood means for your health. (doctorshealthpress.com)
- First, this review aims to summarise the effects of moderate to high terrestrial altitude (1500-4000 m) exposure on patients with pre-existing lung disease, more specifically chronic obstructive pulmonary disease (COPD), sleep apnoea, asthma, bullous or cystic lung disease, pulmonary hypertension and interstitial lung disease. (biomedcentral.com)
- An in-depth report on the causes, diagnosis, treatment, and prevention of chronic obstructive pulmonary disease (COPD) -- emphysema and chronic bronchitis. (adam.com)
- Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States. (adam.com)
- Pulmonary rehabilitation may offer benefits to people who experienced a recent exacerbation of COPD. (adam.com)
- They stress the importance of patient history and physical examination for predicting airflow obstruction, spirometry for screening or diagnosis of COPD, and assessing management strategies including inhaled medications, pulmonary rehabilitation and supplemental oxygen. (adam.com)
- Chronic obstructive pulmonary disease (COPD) is a condition in which there is reduced airflow in the lungs. (adam.com)
- In many patients with advanced COPD, the small sacs where oxygen and carbon dioxide are exchanged are destroyed, gradually depriving the body of enough oxygen. (adam.com)
- This set of medical illustrations depicts chronic obstructive pulmonary disease (COPD), also known as chronic obstructive airway disease (COAD). (doereport.com)
- Among the most prevalent multimorbidities that accompany the aging process, chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) stand out, representing the main causes of hospital admissions in the world. (doaj.org)
- COPD-CHF coexistence confers a marked negative impact on mechanical-ventilatory, cardiocirculatory, autonomic, gas exchange, muscular, ventilatory, and cerebral blood flow, further impairing the reduced exercise capacity and health status of either condition alone. (doaj.org)
- In addition to causing silicosis, crystalline silica exposure has been associated with pulmonary function impairment and COPD. (cdc.gov)
Physiology3
- The diagnosis of IPF is made on the basis of the patient's history, clinical findings, pulmonary physiology, and imaging results. (medscape.com)
- Managing patients at risk for postoperative pulmonary problems requires an understanding of the predictable changes in pulmonary physiology that occur with surgery and anesthesia, as well as knowledge of factors associated with development of postsurgical respiratory compromise. (mhmedical.com)
- 1 , 2 Hence, an appreciation of normal postoperative pulmonary physiology is useful in understanding a number of pulmonary problems seen following surgery. (mhmedical.com)
Hypertension14
- Eight awake lambs with U46619-induced pulmonary hypertension sequentially breathed two concentrations of NO (5 and 20 ppm), followed by inhalation of aerosols generated from solutions containing four concentrations of zaprinast (10, 20, 30, and 50 mg/ml). (asahq.org)
- Aerosolization of a cGMP-selective phosphodiesterase inhibitor alone or combined with NO may be a useful noninvasive therapeutic method to treat acute or chronic pulmonary hypertension. (asahq.org)
- Such imaging of 129Xe gas transfer is expected to be uniquely sensitive to pathologies affecting gas exchange (fibrosis, emphysema, pulmonary hypertension) and provide new insights regarding the normal resting heterogeneity of pulmonary gas exchange. (centerwatch.com)
- The speculated mechanisms of exercise limitation in PLCH include ventilatory limitation, dynamic hyperinflation (DH), cardiocirculatory limitation that encompasses pulmonary hypertension (PH) and impaired gas exchange. (usp.br)
- First, we aimed in this review to evaluate health risks of moderate and high terrestrial altitude travel by patients with pre-existing lung disease, including chronic obstructive pulmonary disease, sleep apnoea syndrome, asthma, bullous or cystic lung disease, pulmonary hypertension and interstitial lung disease. (biomedcentral.com)
- Chronic thromboembolic disease is characterised by persistent pulmonary thromboembolic occlusions without pulmonary hypertension. (ersjournals.com)
- There was a significant improvement in quality of life assessed by the Cambridge pulmonary hypertension outcome review questionnaire. (ersjournals.com)
- Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious condition that results from insufficient resolution of thromboemboli in the pulmonary arteries. (ersjournals.com)
- Appropriate decision making to determine operability on CTEPH patients can be challenging and takes into account the patient's symptoms and functional impairment, severity of pulmonary hypertension (PH), as well as surgical accessibility of thromboembolic lesions and coexistent comorbidities [ 4 , 5 ]. (ersjournals.com)
- It evaluates the role that specialized blood vessel cells, known as 'pericytes', in pulmonary arterial hypertension (PAH). (stanford.edu)
- Limited alveolar gas exchange versus oxygenation failure due to inadequate pulmonary blood flow with pulmonary hypertension differentiate the common forms of pediatric and neonatal respiratory failure. (sts.org)
- The practical management of pulmonary arterial hypertension (PAH) requires an accurate assessment of disease severity and prognosis. (ersjournals.com)
- Pulmonary arterial hypertension (PAH) is a serious and progressive disease of the pulmonary vasculature that can be triggered by a number of known (genetic mutations, toxins, infections or other diseases) and unknown causes. (ersjournals.com)
- In the EARLY (Endothelin Antagonist Trial in Mildly Symptomatic Pulmonary Arterial Hypertension Patients) trial, PAH patients classified as WHO FC II had a mean PVR at entry of 822 dyn·cm·s −5 [ 6 ], approximately 10-fold higher than healthy individuals. (ersjournals.com)
Artery3
- The classical explanation of HPV involves inhibition of hypoxia-sensitive voltage-gated potassium channels in pulmonary artery smooth muscle cells leading to depolarization. (wikipedia.org)
- This contrasts with the classical explanation of HPV which presumes that hypoxia is sensed at the pulmonary artery smooth muscle cell itself. (wikipedia.org)
- Respiratory dysfunction is one of the most frequent complications after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), even in the absence of previous pulmonary diseases (1). (scielo.br)
Edema20
- This hypoxia causes vasoconstriction that ultimately leads to high altitude pulmonary edema (HAPE). (wikipedia.org)
- Pulmonary edema is a condition caused by too much fluid in the lungs. (mayoclinic.org)
- In most cases, heart problems cause pulmonary edema. (mayoclinic.org)
- Pulmonary edema that develops suddenly (acute pulmonary edema) is a medical emergency that needs immediate care. (mayoclinic.org)
- Pulmonary edema can sometimes cause death. (mayoclinic.org)
- Treatment for pulmonary edema depends on the cause but generally includes additional oxygen and medications. (mayoclinic.org)
- Pulmonary edema symptoms may appear suddenly or develop over time. (mayoclinic.org)
- Symptoms depend on the type of pulmonary edema. (mayoclinic.org)
- Symptoms of high-altitude pulmonary edema (HAPE) tend to get worse at night. (mayoclinic.org)
- Pulmonary edema that comes on suddenly (acute pulmonary edema) is life-threatening. (mayoclinic.org)
- The causes of pulmonary edema vary. (mayoclinic.org)
- Pulmonary edema falls into two categories, depending on where the problem starts. (mayoclinic.org)
- If a heart problem causes the pulmonary edema, it's called cardiogenic pulmonary edema. (mayoclinic.org)
- If pulmonary edema is not heart related, it's called noncardiogenic pulmonary edema. (mayoclinic.org)
- Discuss the causes of pulmonary edema. (centura.org)
- Discuss how CPAP aids in improving gas exchange in pulmonary edema. (centura.org)
- Discuss how NTG affects preload and thus aids in reducing pulmonary edema. (centura.org)
- 4 In 1946, Mendelson described a series of obstetrical patients receiving anesthesia who aspirated gastric contents, resulting in bronchospasm, pneumonia, or pulmonary edema. (rtmagazine.com)
- The authors hypothesized that redistribution of pulmonary blood flow can cause increased apparent EVLW secondary to increased perfusion of thermally silent tissue, not increased lung edema. (silverchair.com)
- Both VAP and VAC events were predominantly attributable to pneumonia, pulmonary edema, ARDS, and atelectasis. (cdc.gov)
Embolism4
- Colloquially known as blood clots, deep vein thrombosis (DVT) and pulmonary embolism (PE) are forms of venous thromboembolism (VTE). (medscape.com)
- It can also be classified according to its severity, which is determined on the basis of the presence or absence of hemodynamic instability, the presence or absence of respiratory symptoms, and the anatomic location of the embolism in the pulmonary vasculature. (medscape.com)
- At the regional hospital, a computed tomography scan of the patient's chest (to rule out pulmonary embolism) showed only minimal bibasilar atelectasis. (cmaj.ca)
- Mechanically ventilated patients are at risk for a wide array of preventable pulmonary complications including pneumonia, barotrauma, fluid overload, pulmonary embolism, pneumothorax, and atelectasis. (cdc.gov)
Alveoli8
- Inhalation of certain forms of silica, asbestos and some other respirable dusts can result in pulmonary fibrosis, characterized by destruction of the surfaces of alveoli and respiratory bronchioles. (cdc.gov)
- The alveoli are small sacs where oxygen is exchanged in the lungs. (adam.com)
- Pulmonary fibrosis is an interstitial lung disease of the lower respiratory tract involving damage to the alveoli (air sacs) of the lungs, leading to reduced transfer of oxygen into the bloodstream. (earthclinic.com)
- In mammalian lungs gas exchange occurs in thin-walled air sacs called alveoli, which are surrounded by a dense mesh of capillaries. (stanford.edu)
- Defects in patterning, maintenance or repair of alveoli lead to diseases that compromise gas exchange, including chronic diseases such as bronchopulmonary dysplasia, pulmonary fibrosis and chronic obstructive pulmonary disease, as well as the acute respiratory distress syndromes accompanying severe alveolar injury or virus-induced damage, as in Covid-19. (stanford.edu)
- Emphysema is characterized by decreased gas exchange and the abnormal permanent enlargement of the alveoli, along with destruction of their walls and without obvious fibrosis (emphysematous alveoli). (doereport.com)
- Each lung is composed of air sacs called alveoli - the sites of gas exchange with the blood. (biologyonline.com)
- The gas exchange mechanism that occurs in the pulmonary alveoli. (answerswallet.com)
Interstitial4
- Lung histopathology reveals interstitial infiltration with mononuclear cells, well-defined noncaseating granulomas (sometimes with multinucleated giant cells and calcific inclusions), and varying degrees of pulmonary fibrosis (Meyer 1994). (cdc.gov)
- Moreover, many autoimmune diseases associated with "pulmonary fibrosis", such as scleroderma, are more frequently associated with a related but more inflammatory disease, nonspecific interstitial pneumonitis. (bionity.com)
- In this first full case report we describe a 21-year-old woman who developed interstitial pneumonitis which required endotracheal intubation and immediate utilization of ECMO in order to ensure proper gas exchange. (scirp.org)
- However, it is best known for causing coal workers' pneumoconiosis (CWP), a type of lung disease affecting the tissues and gas-exchange surface of the lung (interstitial lung disease). (cdc.gov)
Capillaries8
- Experimental studies have demonstrated that in healthy individuals the partial pressure of oxygen in blood largely equilibrates with the partial pressure of oxygen in the alveolar space ( Alveolar Oxygen ) roughly one-third of the way through its course through the pulmonary capillaries. (pathwaymedicine.org)
- In other words, the partial pressure gradient of oxygen across the alveolar membrane is eliminated early on as blood moves through the pulmonary capillaries. (pathwaymedicine.org)
- Empirical studies have shown that heavy exercise results in blood travelling through the pulmonary capillaries nearly three times as fast as during rest. (pathwaymedicine.org)
- Consequently, during scenarios of intense physical exertion, the partial pressure of oxygen across the alveolar membrane just barely equilibrates by the time blood has reached the end of the pulmonary capillaries. (pathwaymedicine.org)
- The rate of oxygen diffusion can be so considerably slowed that the partial pressure gradient of oxygen across the alveolar membrane may not equilibrate by the time blood reaches the ends of the pulmonary capillaries. (pathwaymedicine.org)
- Experimental studies have demonstrated that the partial pressure of carbon dioxide in blood rapidly equilibrates with the partial pressure of carbon dioxide in the alveolar space ( Alveolar Carbon Dioxide ) early in its course through the pulmonary capillaries. (pathwaymedicine.org)
- Eventually, the smallest arteries, vessels called arterioles, further branch into tiny capillaries, where nutrients and wastes are exchanged, and then combine with other vessels that exit capillaries to form venules, small blood vessels that carry blood to a vein, a larger blood vessel that returns blood to the heart. (lumenlearning.com)
- Accordingly, we can conclude that gas exchange occurs between the tissue cells and the blood in the capillaries. (answerswallet.com)
Postoperative pulmonary2
- Using computed tomography (CT), we investigated postoperative pulmonary alterations and their impact on blood oxygenation. (scielo.br)
- Postoperative pulmonary complications constitute a significant cause of morbidity and mortality following surgery. (mhmedical.com)
Perfusion6
- Given these features, it is clear that oxygen gas exchange is perfusion-limited in a normal, healthy lung. (pathwaymedicine.org)
- As a result, heavy exercise pushes pulmonary gas exchange to the cusp of switching from perfusion-limitation to diffusion-limitation. (pathwaymedicine.org)
- Consequently, pulmonary gas exchange of carbon dioxide is perfusion-limited . (pathwaymedicine.org)
- MR imaging of pulmonary perfusion using hyperpolarized 129Xe dissolved in an injectable carrier. (mpg.de)
- MR imaging of pulmonary perfusion and gas exchange by intravenous injection of hyperpolarized 129Xe. (mpg.de)
- The abrupt increase in EVLW and shunt fraction after endotoxin administration is consistent with inactivation of hypoxic pulmonary vasoconstriction and increased perfusion to already flooded lung regions that were previously thermally silent. (silverchair.com)
Emphysema1
- Chronic obstructive pulmonary disease refers to chronic bronchitis, emphysema, and combined presentations of these two diseases. (cdc.gov)
Oxygenation4
- ARDS involves an acute alveolar-capillary membrane inflammatory response that is characterized by poor oxygenation and pulmonary infiltrates, resulting in "stiffness" of the lungs leading to hypoxic failure [ 10 , 11 ]. (biomedcentral.com)
- Extracorporeal membrane oxygenation can achieve sufficient gas exchange in severe acute respiratory distress syndrome. (researchgate.net)
- Utilization of Extracorporeal Membrane Oxygenation for Pulmonary Toxicity Caused by Inhaled Synthetic Cannabinoid. (scirp.org)
- Hypoxic pulmonary vasoconstriction (HPV) is a fundamental homeostatic mechanism by which the lung preserves oxygenation during injury. (silverchair.com)
Complications2
- While the exact pathophysiology of these interesting and recent pulmonary complications is unknown, the recent increase in exposure to SC via water pipe systems and vaping suggests that there will be many more cases of patients that will require ECMO as a form of life-saving therapy. (scirp.org)
- Many postoperative respiratory complications relate to exaggerations of the expected postoperative changes in pulmonary function that occur as a result of the surgery itself, anesthesia, or various pharmacologic interventions. (mhmedical.com)
Vasculature2
- Inhaled NO selectively dilated the pulmonary vasculature. (asahq.org)
- Beyond its role as an antioxidant and antimicrobial, nitric oxide acts as a vasodilator upon its release into the respiratory vasculature, thus promoting optimal pulmonary gas exchange. (dimensionsofdentalhygiene.com)
Diseases8
- Non-invasive imaging of pulmonary function is expected to provide critical insights that are needed to spur progress in characterizing and treating chronic pulmonary diseases. (centerwatch.com)
- Abstract Extracorporeal life support (ECLS) is a well-established technique for the treatment of different cardiac and pulmonary diseases, e.g., congenital heart disease and acute respiratory distress syndrome. (researchgate.net)
- The diseases might differ, but they all can create secretions in a patient's airways that inhibit gas exchange in the lungs and negatively impact pulmonary health. (hme-business.com)
- Observations during influenza epidemics indicate that most influenza-related deaths occur among: (1) persons older than 65 years of age and (2) persons with chronic, underlying disorders of the cardiovascular, pulmonary, and/or renal systems, as well as those with metabolic diseases (including diabetes mellitus), severe anemia, and/or compromised immune function. (cdc.gov)
- Hydrogen Peroxide Inhalation is yet again a popular home remedy for lung diseases of various kinds, as here for pulmonary fibrosis. (earthclinic.com)
- ABSTRACT Pulmonary rehabilitation is a tool that is receiving more acceptance in chronic lung diseases. (who.int)
- A retrospective study was made in Riyadh, Saudi Arabia, on the impact of pulmonary rehabilitation on respiratory parameters and health care utilization in a group of outpatients with chronic lung diseases other than chronic obstructive pulmonary disease. (who.int)
- Measure the effects of continued smoking on chronic pulmonary diseases. (clevelandclinic.org)
Arterial pressure2
- It is characterised by vascular remodelling causing persistent elevation of pulmonary arterial pressure (PAP) and pulmonary vascular resistance (PVR) leading to right ventricular failure [ 1 ]. (ersjournals.com)
- Together with associated vasoconstriction and the development of in situ thrombosis, this proliferative and obstructive remodelling of pulmonary blood vessel walls leads to a progressive increase in pulmonary vascular resistance (PVR) and, subsequently, increased pulmonary arterial pressure ( P pa ) with a resultant increase in afterload on the right ventricle. (ersjournals.com)
Airway3
- Chronic bronchitis is characterized by a chronic productive cough, accompanied by a narrowed airway and decreased gas exchange. (doereport.com)
- Your healthcare provider may order pulmonary function tests if you have lung or airway symptoms like cough or shortness of breath, are undergoing surgery or use tobacco products (smoke). (clevelandclinic.org)
- Annual follow-up lung function measurements featuring FRC determined by whole-body plethysmography and multibreath nitrogen washouts, effective specific airway resistance, flow-volume curves, LCI, and gas exchange characteristics were analyzed by linear mixed-model analysis and Kaplan-Meier statistics. (nih.gov)
Hypoxic Pulmonary Vasoco2
- Hypoxic pulmonary vasoconstriction (HPV), also known as the Euler-Liljestrand mechanism, is a physiological phenomenon in which small pulmonary arteries constrict in the presence of alveolar hypoxia (low oxygen levels). (wikipedia.org)
- After stabilized lung injury, endotoxin was administered to inactivate hypoxic pulmonary vasoconstriction. (silverchair.com)
20221
- The Wall Center for Pulmonary Vascular Disease welcomes the 2022-2023 fellows. (stanford.edu)
Obstructive6
- Of those with pulmonary function abnormalities, one third of patients present with an obstructive pattern, one fourth with a restrictive pattern of decreased lung volumes, one third with an isolated decreased DLCO, and the remainder have a mixed pattern of obstruction and restriction with varying amounts of gas exchange abnormality (Newman and Maier 2001). (cdc.gov)
- 78. Gaynor-Sodeifi K*, Lewthwaite H**, Jenkins AR**, Belo LF*, Koch E*, Mujaddid A*, Raffoul D*, Tracey L*, Jensen D . The association between fat-free mass and exercise test outcomes in people with chronic obstructive pulmonary disease: A systematic review . (mcgill.ca)
- The patient was given methylprednisolone, bronchodilators and intravenous azithromycin treatment for possible exacerbation of chronic obstructive pulmonary disease. (cmaj.ca)
- The two major clinical issues in CF are chronic obstructive pulmonary disease, secondary to abnormal respiratory tract secretions, and malnutrition secondary to pancreatic insufficiency. (renalandurologynews.com)
- Une étude rétrospective a été menée à Riyad (Arabie saoudite) pour connaître l'impact de la rééducation pulmonaire d'une part sur les paramètres respiratoires d'un groupe de patients en consultation externe pour des affections pulmonaires chroniques autres que la bronchopneumopathie chronique obstructive (BPCO) et d'autre part sur leur utilisation des soins de santé. (who.int)
- Chronic obstructive pulmonary disease is a leading cause of morbidity and mortality in the United States and world-wide. (cdc.gov)
Vascular disease3
- They accept that assessment of the relation between treatment effect and severity of pulmonary vascular disease would have been valuable. (bmj.com)
- Established in 2001, the eBay Clinical Fellowship in Pulmonary Vascular Disease is a post-doctoral fellowship devoted exclusively to clinical training in pulmonary vascular disease. (stanford.edu)
- In view of this, measures of cardiac function and not just the extent of the pulmonary vascular disease take on particular significance when assessing central cardiopulmonary haemodynamics. (ersjournals.com)
Critical Care Med3
- Dr. Vinicio de Jesus Perez , Associate Professor, Division of Pulmonary, Allergy and Critical Care Medicine and Wall Center faculty, was recently featured in a Telemundo article "Entrenamientos gratis de CPR para la comunidad hispana. (stanford.edu)
- Congratulations to Dr. Vinicio de Jesus Perez , Associate Professor, Division of Pulmonary, Allergy and Critical Care Medicine for a $3.5M award, funding the renewal of his R01 NIH grant. (stanford.edu)
- Congratulations to the Stanford Clinical Center for the NIH Lung Transplant Consortium including Dr. Mark Nicolls, Chief of the Division of Pulmonary and Critical Care Medicine and a steering committee member for the Wall Center, and Amy Tian, PhD, Project Leader in the Nicolls Lab (Wall Center Member), for being awarded just one of eight NIH Lung Transplant Consortium Center grants in the country. (stanford.edu)
Shortness of bre2
- A pulmonary fibrosis diagnosis likely comes after you have experienced symptoms including shortness of breath, weight loss, exhaustion, and possibly sore muscles. (earthclinic.com)
- It causes changes in the chest radiograph and, in more serious cases, can cause shortness of breath, loss of pulmonary function, and even death. (cdc.gov)
Hypoxemia2
- In such a scenario, oxygen gas is rendered diffusion-limited and results in reductions in the partial pressure of arterial oxygen, thus yielding hypoxemia. (pathwaymedicine.org)
- 2001). For many patients with CBD, results of resting pulmonary function tests, including spirometry values, lung volumes, and carbon monoxide-diffusing capacity (DLCO), are normal but resting and exercise arterial blood gas levels indicate hypoxemia. (cdc.gov)
Pathophysiology1
- In this review we highlight the overall pulmonary pathophysiology of COVID-19, and provide an overview of animal models well-suited for mechanistic studies and preclinical therapeutic trials. (ersjournals.com)
Function38
- Repeat pulmonary function and gas exchange tests. (cdc.gov)
- and physiologic evidence of restriction and impaired gas exchange on pulmonary function testing. (medscape.com)
- The purpose of this study is to develop and evaluate the usefulness of MRI using 129Xe gas for regional assessment of pulmonary function. (centerwatch.com)
- The current primary diagnostic measure is pulmonary function testing (PFT), which was introduced in the mid-19th century, yet remains the standard of care today. (centerwatch.com)
- The key role for HP 129Xe MRI is that it can enable non-invasive high-resolution imaging of all aspects of pulmonary structure and function. (centerwatch.com)
- We have also demonstrated the fundamentally new capability to directly visualize the uptake of 129Xe into the pulmonary capillary blood and tissues, which can provide an even more complete picture of pulmonary function by supplying regional gas exchange information. (centerwatch.com)
- Hence, the affected areas lose their function of gas exchange. (wikipedia.org)
- Lung function is significantly affected in cases of pulmonary agenesis, demonstrated by reduction in forced expiratory volume and forced vital capacity. (wikipedia.org)
- The retention of bronchial secretions often leads to recurrent pulmonary infections, adding to damage in lung function, hence causing respiratory stress. (wikipedia.org)
- Methods: In a cross-sectional study, 35 patients with PLCH underwent clinical evaluation, transthoracic echocardiography, six-minute walk test, pulmonary function tests, and incremental treadmill cardiopulmonary exercise test (CPET) with evaluation of DH. (usp.br)
- Resting pulmonary function testing was performed. (cdc.gov)
- Oxygen uptake (VO2), carbon-dioxide production (VCO2), respiratory exchange rate, tidal volume, and other variables related to respiratory function were monitored. (cdc.gov)
- Pulmonary function or gas exchange during exercise was not affected by the presence of circumscribed pleural plaques or diffuse pleural thickening. (cdc.gov)
- The key issue facing clinicians is whether the presenting history, symptoms/signs, radiology, and pulmonary function testing are collectively in keeping with the diagnosis of IPF (which carries the relatively poor prognosis described above) or whether the findings are due to another process. (bionity.com)
- Since the pressure within arteries is relatively high, the vasa vasorum must function in the outer layers of the vessel or the pressure exerted by the blood passing through the vessel would collapse it, preventing any exchange from occurring. (lumenlearning.com)
- This chapter focuses initially on changes in pulmonary function with surgery. (mhmedical.com)
- Five principal categories of change in pulmonary function with surgery may be considered: (1) lung volumes, (2) diaphragm function, (3) gas exchange, (4) control of breathing, and (5) lung defense mechanisms ( Table 103-1 ). (mhmedical.com)
- Your doctor will start with standard lung function tests but will have to progress at least to chest imaging and perhaps to a lung biopsy for conclusive diagnosis of pulmonary fibrosis. (earthclinic.com)
- Our analysis suggests a novel mechanism of alveolar formation and provides the foundation for investigations of the structure, function and maintenance of the gas exchange surface in health, disease, aging and evolution. (stanford.edu)
- In order to identify the best way to use such surrogate markers in assessing the course of disease in PAH, we need to understand not only how the primary lesion, i.e. pulmonary vascular remodelling, is triggered and develops, but also how the right ventricle adapts and how its function deteriorates over time. (ersjournals.com)
- Pulmonary function tests (PFTs) determine how well your lungs work. (clevelandclinic.org)
- Pulmonary function testing measures how well your lungs work. (clevelandclinic.org)
- Spirometry is a common pulmonary function test. (clevelandclinic.org)
- Pulmonary function tests (PFTs) include different kinds of breathing tests that measure how well your lungs exchange air. (clevelandclinic.org)
- Another name for pulmonary function tests is lung function tests. (clevelandclinic.org)
- What is the most common pulmonary function test? (clevelandclinic.org)
- When is pulmonary function testing performed? (clevelandclinic.org)
- Even if you don't have symptoms, your healthcare provider may order a pulmonary function test as part of a routine physical examination . (clevelandclinic.org)
- When would pulmonary function testing be needed? (clevelandclinic.org)
- Who performs pulmonary function testing? (clevelandclinic.org)
- A specially trained respiratory therapist usually performs pulmonary function testing. (clevelandclinic.org)
- How does pulmonary function testing work? (clevelandclinic.org)
- A pulmonary function test is relatively simple. (clevelandclinic.org)
- How do I prepare for a pulmonary function test? (clevelandclinic.org)
- Can you eat before a pulmonary function test? (clevelandclinic.org)
- What should I expect on the date of pulmonary function testing? (clevelandclinic.org)
- You'll take a PFT at a pulmonary function lab at an outpatient office or a hospital. (clevelandclinic.org)
- What should I expect during pulmonary function testing? (clevelandclinic.org)
Tissue10
- Pulmonary agenesis is the complete absence of lung tissue, including bronchial tree, lung parenchyma, and supporting vasculatures. (wikipedia.org)
- The severity of unilateral pulmonary agenesis varies depending on the area of tissue affected, being either a single lobe or a whole lung. (wikipedia.org)
- The difference between pulmonary agenesis and aplasia is that pulmonary agenesis has complete absence of lung tissue, airways, and lung vessels while pulmonary aplasia has complete absence of lung tissue and lung vessels, but have some incompletely developed short airways. (wikipedia.org)
- Most of these patients died of acute lung injury (ALI) or progressive pulmonary fibrosis, because PQ tends to accumulate in lung tissue through the polyamine uptake system and so the pulmonary concentration becomes much higher than that in plasma and other organs [ 2 ]. (hindawi.com)
- However, it is perhaps better characterized as an abnormal and excessive deposition of fibrotic tissue in the pulmonary interstitium with minimal associated inflammation. (bionity.com)
- "Pulmonary" means lung, and "fibrosis" is scar tissue, which causes lungs to become stiff and makes it hard to get oxygen to into the blood. (every1dies.org)
- Pulmonary and tissue gaseous exchanges. (unica.it)
- Computed tomographic measurements quantified an endotoxin-induced increase in pulmonary blood flow to poorly aerated regions with no change in total lung tissue volume. (silverchair.com)
- A number of habits, respiratory toxins, and health issues can cause scarring of your lung tissue, which is the principle symptom of pulmonary fibrosis. (earthclinic.com)
- Meiners and his team are currently working on tissue mechanics and tissue damage through gas bubbles in the spinal cord, or spinal cord decompression sickness. (dansa.org)
Disease10
- Certain pulmonary disease result in pathological thickening of the alveolar membrane which in turn can substantially reduce the diffusing capacity of oxygen and thus its rate of diffusion across the membrane. (pathwaymedicine.org)
- Because 129Xe MRI uses no ionizing radiation, and only an inhaled gas contrast agent, it has the potential to be used in longitudinal studies to test the effects of therapy or monitor progression of disease noninvasively. (centerwatch.com)
- Using pulmonary gas exchange to estimate shunt and deadspace in lung disease: theoretical approach and practical basis. (ucsd.edu)
- However, the ability of these assays to predict the pulmonary disease producing potential of various dusts is imperfect owing to some "false positive" results. (cdc.gov)
- Introduction: Pulmonary Langerhans cell histiocytosis (PLCH) is a smokingrelated diffuse cystic disease, which determines reduced exercise capacity. (usp.br)
- Pulmonary fibrosis has often been called an autoimmune disease . (bionity.com)
- Early surgical treatment with pulmonary endarterectomy may improve symptoms and prevent disease progression. (ersjournals.com)
- We sought to assess the outcome of pulmonary endarterectomy in symptomatic patients with chronic thromboembolic disease. (ersjournals.com)
- In this carefully selected cohort of chronic thromboembolic disease patients, pulmonary endarterectomy resulted in significant improvement in symptoms and quality of life. (ersjournals.com)
- Role of genetic factors in pulmonary disease susceptibility. (cdc.gov)
Disorders2
- Although pulmonary agenesis, aplasia and hypoplasia are lethal congenital disorders all resulting from underdevelopment of lungs, pulmonary agenesis and aplasia differ from pulmonary hypoplasia in their underlying cause. (wikipedia.org)
- [5] It should be noted that these features are non-specific and can occur in a spectrum of other pulmonary disorders. (bionity.com)
Physiological3
- However, a number of physiological and pathological scenarios can modify the character of oxygen gas exchange as described below. (pathwaymedicine.org)
- Impaired gas exchange, as manifested by increases in the physiological dead space volume/tidal volume (VD/VT) ratio and alveolar arterial oxygen pressure difference, was seen in subjects with asbestos is. (cdc.gov)
- To perform this research, I combine techniques such as transcranial magnetic stimulation, high-density electromyography, near-infrared spectroscopy, and pulmonary gas exchange to identify aetiologies of physiological alterations and adaptations. (northumbria.ac.uk)
Patients3
- The exercise capacity test reveals gas exchange or ventilatory abnormalities, including an elevation in the dead space-to-tidal volume ratio, in most patients with CBD. (cdc.gov)
- Although age in itself is not a risk factor for altitude intolerance, older patients are more prone to pulmonary comorbidities. (biomedcentral.com)
- The ability of the right ventricle to adapt to this afterload is the key determinant of symptoms and survival, and ultimately, although characterised by pulmonary vasculopathy, it is the failure of the right ventricle that is the main cause of death in patients with PAH [ 2 ]. (ersjournals.com)
Oxygen and carbon dioxide2
- The extensive surface area and the thin barrier permit the rapid exchange of large quantities of oxygen and carbon dioxide by diffusion. (biologyonline.com)
- Blood gases are a measurement of how much oxygen and carbon dioxide are in your blood. (adam.com)
HAPE1
- Acute mountain sickness (AMS), with headache, gastrointestinal symptoms, weakness and sleeping difficulties, in the mild form to acute high altitude cerebral oedema (HACE), in the most severe form, as well as high altitude pulmonary oedema (HAPE) can develop when travelling to high altitude [ 2 ]. (biomedcentral.com)
Changes in pulmonary1
- The cardiac ventricle of squamate and chelonian vertebrates lacks anatomical septation, which motivated studies of the possible significance and functional consequences of changes in pulmonary and systemic blood flow in different species ( Hicks and Wang, 2012 ). (biologists.com)
Patient's1
- Innovative gas exchange and metabolics technologies for optimizing the patient's nutrition, work of breathing and ventilator settings in order to help the patient in the healing and weaning process. (georgiananesthesia.com)
Symptoms1
- By the time a patient presents with symptoms, even with "early" symptoms, classified as being in World Health Organization (WHO) functional class (FC) II, PVR is already substantially above normal, suggesting advanced pulmonary vascular remodelling. (ersjournals.com)
Induce pulmonary2
- High-altitude mountaineering can induce pulmonary hypoxia due to decreased atmospheric pressure. (wikipedia.org)
- A second mechanism has also been proposed in which dust damage to the macrophage causes the release of mediator substances which induce pulmonary fibroblast cell proliferation and increased collagen synthesis. (cdc.gov)
Common pulmonary1
- The pathogenesis of PAH is multifactorial, involving a number of biochemical pathways and cell types [ 1 ], but all forms of PAH, regardless of underlying aetiology, share a common pulmonary vasculopathy characterised by intimal proliferation, medial hypertrophy and the development of plexiform lesions. (ersjournals.com)
Impairment1
- In most cases of pulmonary agenesis, surgical resection is performed to remove the malformed lobe or the entire defected lung of the patient depending on the severity of the respiratory impairment. (wikipedia.org)
Mechanics3
- Two laboratory methods recently deployed, esophageal pressure (P es ) measurement and functional residual capacity (FRC) estimation by gas dilution, have the potential to refine our understanding of the mechanics of the lung itself. (rcjournal.com)
- Lung mechanics, gas exchange and central circulation during treatment of intra-abdominal hemorrhage with pneumatic anti-shock garment and intra-aortic balloon occlusion. (lu.se)
- The effects of this treatment on circulation, lung mechanics and gas exchange were studied. (lu.se)
Carbon3
- This can cause the levels of carbon dioxide to rise in your blood, as the lungs are having a hard time exchanging the carbon dioxide for oxygen. (doctorshealthpress.com)
- The basic answer is that anything that can prevent the exchange of carbon dioxide in your body for oxygen is a potential cause. (doctorshealthpress.com)
- Gas exchange allows the body to replenish the oxygen and eliminate the carbon dioxide. (medlineplus.gov)
Toxicity2
- Such modification of the mineral surface might interfere with surface sites responsible for the toxicity of dusts for pulmonary macrophages, thus interrupting the early stages of the process of fibrosis. (cdc.gov)
- The acute and chronic findings of direct pulmonary toxicity do not include the depression of respiratory drive caused by SC [4] [5]. (scirp.org)
Systemic3
- Arteries and veins transport blood in two distinct circuits: the systemic circuit and the pulmonary circuit. (lumenlearning.com)
- Pulmonary veins then return freshly oxygenated blood from the lungs to the heart to be pumped back out into systemic circulation. (lumenlearning.com)
- During swimming, this mechanism also increases heart rate while vagal withdrawal facilitates a systemic to pulmonary (left to right) shunt. (biologists.com)
Arteries3
- The treatment of choice, and only potentially curative option, is surgical disobliteration of the pulmonary arteries by pulmonary endarterectomy (PEA) [ 3 ]. (ersjournals.com)
- In contrast, in the pulmonary circuit, arteries carry blood low in oxygen exclusively to the lungs for gas exchange. (lumenlearning.com)
- Larger arteries and veins contain small blood vessels within their walls known as the vasa vasorum -literally "vessels of the vessel"-to provide them with this critical exchange. (lumenlearning.com)
Hypoxia3
- Recently it was proposed that hypoxia is sensed at the alveolar/capillary level, generating an electrical signal that is transduced to pulmonary arterioles through gap junctions in the pulmonary endothelium to cause HPV. (wikipedia.org)
- The angiogenic response of the pulmonary vascular bed as a result of exposure to chronic hypoxia has been recognized in other species, but similar studies are not known in broilers. (unal.edu.co)
- It was evaluated the mRNA expression of genes HIF-1α , HIF-2α, VEGF, Flk-1, Flt-1, HGF, HGFR, EGF and EGFR and the pulmonary vascular density for broilers reared at 460 meters and at 2638 meters, under natural conditions of hypobaric hypoxia, and for chickens that developed HAP and those who did not. (unal.edu.co)
Inhalation1
- Inhaled zaprinast selectively dilated the pulmonary circulation and potentiated and prolonged the pulmonary vasodilating effects of inhaled NO. The net transpulmonary release of cGMP was increased by inhalation of NO, zaprinast, or both. (asahq.org)
Clinical1
- Frequently seen clinical features includes dyspnea, respiratory distress, recurrent pulmonary infections, and limited exercise tolerance. (wikipedia.org)
Lungs for gas exchange1
- Despite the parabronchial pulmonary system of birds allows greater efficiency in pulmonary gas exchange, the breeding programs of broiler chickens have resulted collaterally in a decrease of ability of lungs for gas exchange. (unal.edu.co)
Intravenous1
- [10] We and others recently reported the potentiation and prolongation of the pulmonary vasodilating effects of inhaled NO by intravenous zaprinast in lambs. (asahq.org)
Acute respirat1
- Veno-venous extracorporeal lung assist (ECLA) can provide sufficient gas exchange even in most severe cases of acute respiratory distress syndrome. (researchgate.net)