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Pulmonary EmphysemaEmphysemaPancreatic Elastasealpha 1-Antitrypsin DeficiencySubcutaneous Emphysemaalpha 1-AntitrypsinLungMatrix Metalloproteinase 12Pulmonary AlveoliMediastinal EmphysemaRespiratory Function TestsSmokeHeliumPulmonary Disease, Chronic ObstructivePneumonectomyVasculitis, Leukocytoclastic, CutaneousElastinPanniculitisSmokingTomography, X-Ray ComputedBronchoalveolar Lavage FluidForced Expiratory VolumePulmonary FibrosisLung CompliancePneumoniaDisease Models, AnimalLung DiseasesBronchiMice, Inbred C57BLTobaccoCoughLung Diseases, ObstructivePubMedPeriodicals as TopicBooksInternal MedicineEvidence-Based MedicineWeight GainAir SacsSkatoleVeterinary MedicineHypertension, PulmonarySyndromePulmonary MedicineDyspneaSpirometryTelepathologyUrologyBronchitis, ChronicBronchitisNephrology
Pulmonary Emphysema: Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.Emphysema: A pathological accumulation of air in tissues or organs.Pancreatic Elastase: A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.alpha 1-Antitrypsin Deficiency: Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN that manifests primarily as PULMONARY EMPHYSEMA and LIVER CIRRHOSIS.Subcutaneous Emphysema: Presence of air or gas in the subcutaneous tissues of the body.alpha 1-Antitrypsin: Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Matrix Metalloproteinase 12: A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.Pulmonary Alveoli: Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.Mediastinal Emphysema: Presence of air in the mediastinal tissues due to leakage of air from the tracheobronchial tree, usually as a result of trauma.Respiratory Function Tests: Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.SmokeHelium: Helium. A noble gas with the atomic symbol He, atomic number 2, and atomic weight 4.003. It is a colorless, odorless, tasteless gas that is not combustible and does not support combustion. It was first detected in the sun and is now obtained from natural gas. Medically it is used as a diluent for other gases, being especially useful with oxygen in the treatment of certain cases of respiratory obstruction, and as a vehicle for general anesthetics. (Dorland, 27th ed)Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.Pneumonectomy: The excision of lung tissue including partial or total lung lobectomy.Vasculitis, Leukocytoclastic, Cutaneous: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.ElastinPanniculitis: General term for inflammation of adipose tissue, usually of the skin, characterized by reddened subcutaneous nodules.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Forced Expiratory Volume: Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.Lung Compliance: The capability of the LUNGS to distend under pressure as measured by pulmonary volume change per unit pressure change. While not a complete description of the pressure-volume properties of the lung, it is nevertheless useful in practice as a measure of the comparative stiffness of the lung. (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p562)Pneumonia: Infection of the lung often accompanied by inflammation.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Lung Diseases: Pathological processes involving any part of the LUNG.Bronchi: The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI.Mice, Inbred C57BLTobacco: A plant genus of the family SOLANACEAE. Members contain NICOTINE and other biologically active chemicals; its dried leaves are used for SMOKING.Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.BooksInternal Medicine: A medical specialty concerned with the diagnosis and treatment of diseases of the internal organ systems of adults.Evidence-Based Medicine: An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)Weight Gain: Increase in BODY WEIGHT over existing weight.Air Sacs: Thin-walled sacs or spaces which function as a part of the respiratory system in birds, fishes, insects, and mammals.SkatoleVeterinary Medicine: The medical science concerned with the prevention, diagnosis, and treatment of diseases in animals.Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.Syndrome: A characteristic symptom complex.Pulmonary Medicine: A subspecialty of internal medicine concerned with the study of the RESPIRATORY SYSTEM. It is especially concerned with diagnosis and treatment of diseases and defects of the lungs and bronchial tree.Dyspnea: Difficult or labored breathing.Spirometry: Measurement of volume of air inhaled or exhaled by the lung.Telepathology: Transmission and interpretation of tissue specimens via remote telecommunication, generally for the purpose of diagnosis or consultation but may also be used for continuing education.Urology: A surgical specialty concerned with the study, diagnosis, and treatment of diseases of the urinary tract in both sexes, and the genital tract in the male. Common urological problems include urinary obstruction, URINARY INCONTINENCE, infections, and UROGENITAL NEOPLASMS.Bronchitis, Chronic: A subcategory of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. The disease is characterized by hypersecretion of mucus accompanied by a chronic (more than 3 months in 2 consecutive years) productive cough. Infectious agents are a major cause of chronic bronchitis.Bronchitis: Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.Nephrology: A subspecialty of internal medicine concerned with the anatomy, physiology, and pathology of the kidney.

Fragile lung in the Marfan syndrome. (1/1021)

Two cases of the Marfan syndrome presented with spontaneous pneumothorax. Both had chest radiographs showing bilateral bullae in the upper lung zones and pulmonary function tests consistent with mild emphysema. There were dereases in forced expiratory flow rates at low lung volumes, carbon monoxide transfer factor, and lung elastic recoil. It is suggested that pneumothorax and bullous emphysema in this syndrome are caused by a weakness in the pulmonary connective tissue framework.  (+info)

Detection of anti-cytokeratin 8 antibody in the serum of patients with cryptogenic fibrosing alveolitis and pulmonary fibrosis associated with collagen vascular disorders. (2/1021)

BACKGROUND: It has been suggested that the humoral immune system plays a role in the pathogenesis of cryptogenic fibrosing alveolitis (CFA). Although circulating autoantibodies to lung protein(s) have been suggested, none of the lung proteins have been characterised. The purpose of this study was to determine the antigen to which the serum from patients with pulmonary fibrosis reacted. METHODS: The anti-A549 cell antibody was characterised in a patient with CFA using Western immunoblotting and immunohistochemical staining of A549 cells. As we identified that one of the antibodies against A549 cells was anti-cytokeratin 8, the expression of mRNA of cytokeratin 8 in A549 cells was evaluated. In addition, we attempted to establish an enzyme linked immunosorbent assay to measure the levels of anti-cytokeratin 8 antibody in the serum of patients with CFA and pulmonary fibrosis associated with collagen vascular disorders (PF-CVD). RESULTS: Initially two anti-A549 cell antibodies were detected in the serum of patients with pulmonary fibrosis, one of which was characterised as anticytokeratin 8 antibody by Western immunoblotting. We were able to establish an ELISA to measure anti-cytokeratin 8 antibody and found significantly higher levels in patients with CFA and PF-CVD than in normal volunteers, patients with sarcoidosis, pneumonia, and pulmonary emphysema. CONCLUSIONS: One of the anti-A549 cell antibodies in the serum of patients with CFA was against cytokeratin 8. The serum levels of anti-cytokeratin 8 antibody were increased in patients with CFA and PF-CVD. These results suggest that anticytokeratin 8 antibody may be involved in the process of lung injury in pulmonary fibrosis.  (+info)

Improvements in thoracic movement following lung volume reduction surgery in patients with severe emphysema. (3/1021)

In twelve patients with severe emphysema who underwent lung volume reduction surgery (LVRS), we assessed the results of dyspnea scale, pulmonary function, 6-minute walk distance (6MD), and thoracic movement prior to and 6 months following LVRS. Postoperatively, forced expiratory volume (FEV1), maximum inspiratory mouth pressures (MIP), maximum expiratory mouth pressures (MEP), maximum voluntary ventilation (MVV), diffusing capacity for carbon monoxide (DLCO), partial pressure of oxygen (PaO2) and 6MD were significantly increased with the decrease in dyspnea scale and lung hyperinflation. Thoracic movement, as assessed by the bilateral lung area ratio of the mid-sagittal dimension of dynamic magnetic resonance imaging (MRI) at full inspiration to that at full expiration, was significantly increased. The improvement in thoracic movement was significantly correlated with the increases in FEV1, MVV, and MIP, and with the decrease in residual volume (RV), and with the improvement in the dyspnea scale. These findings suggest that LVRS is an effective procedure for improving not only the airflow limitation and gas exchange but also the thoracic movement in severe emphysema, and these improvements may contribute to an increase in exercise performance and relief of dyspnea.  (+info)

Physiological basis of improvement after lung volume reduction surgery for severe emphysema: where are we? (4/1021)

Lung volume reduction surgery has become an accepted therapeutic option to relieve the symptoms of selected patients with severe emphysema. In a majority of these patients, it causes objective as well as subjective functional improvement. A proper understanding of the physiological determinants underlying these beneficial effects appears very important in order to better select patients for the procedure that is currently largely carried out on an empirical basis. Lung volume reduction surgery has two distinct effects. Firstly, it causes an increased elastic recoil, which at least partially explains the enhanced maximal expiratory flow. Secondly, it is associated with a reduction of hyperinflation which allows for an increase in global inspiratory muscle strength and in diaphragmatic contribution to tidal volume as well as a decrease in the inspiratory elastic load imposed by the chest wall. Taken together, these effects result in a reduced work of breathing and in an enhanced maximal ventilation which both contribute to the increased exercise capacity and reduced dyspnoea after surgery. The improved lung recoil and the reduced hyperinflation after volume reduction surgery were the primary postulates upon which the usual selection criteria for the procedure were based. It is now likely that these are correct. Nevertheless, some patients do not benefit from lung volume reduction surgery and the current literature does not allow for a refinement of the selection process from a physiological point of view. The exact mechanisms underlying the improvement in lung recoil, lung mechanics, and respiratory muscle function remain incompletely understood. Moreover, the effects of lung volume reduction surgery on gas exchange and pulmonary haemodynamics still need to be more fully investigated. An analysis of the characteristics of patients who do not benefit from the procedure and the development of an animal model for lung volume reduction surgery would probably help address these important issues.  (+info)

Subjective differentiation of normal and pathological bronchi on thin-section CT: impact of observer training. (5/1021)

The effect of observer training on sensitivity, specificity and interobserver agreement in the differentiation between normal and pathological bronchi on computed tomography (CT) was studied. The wall thickness of bronchi with normal walls and with pathologically thickened walls were subjectively scored by three independent observers before and after a training period of 2 weeks. Sensitivity, specificity and interobserver agreement were calculated for reading sessions before and after training. Increase and decrease in agreement after training were determined. There was a statistically significant difference (p=0.001) between objectively measured wall thickness of normal and pathological bronchi, both for reference bronchi and for bronchi used for reading sessions. While training increased interobserver agreement, it had no effect on sensitivity (0.46 versus 0.44 after training) and specificity (0.71 versus 0.72 after training) in detecting pathological bronchi. Increased agreement after training was significantly (p=0.001) more frequent than decreased agreement. There is a discrepancy between the effect of training on interobserver agreement and on sensitivity and specificity in the subjective differentiation between normal and pathological bronchi. Interobserver agreement alone is not a reliable indicator of a beneficial effect of training in the evaluation of this parameter.  (+info)

Outcome of asthma: longitudinal changes in lung function. (6/1021)

Current knowledge about factors determining outcome of asthma is limited, but observations over the last few decades suggest that active asthma has a negative impact on the longitudinal changes in lung function. This review aims to give an overview of the present knowledge concerning longitudinal changes in lung function, including clinical markers for distinctly poor outcome with regard to lung function, in children and adults suffering from asthma. The majority of patients with asthma have a good prognosis. However, some patients with asthma, especially those with more severe disease, are at risk of impaired growth of lung function during childhood, a lower maximally attained level of lung function and excessive decline in lung function in adulthood, which may lead to life-threatening lung function impairment. Clinical markers of poorly controlled airway inflammation appear to have a negative impact on the longitudinal changes in lung function, and disease progression to nonreversible airflow obstruction may be observed in a minority of patients with asthma. Early intervention with anti-inflammatory therapy may improve the short-term outcome of asthma, but long-term controlled studies are clearly needed in order to verify whether or not treatment, especially with inhaled corticosteroids, according to the current international guidelines alters the natural history of asthma, i.e. disease progression with regard to changes in lung function and possible development of nonreversible airflow obstruction.  (+info)

Surgical aspects and techniques of lung volume reduction surgery for severe emphysema. (7/1021)

Lung volume reduction surgery (LVRS) has become an accepted procedure for palliative treatment of diffuse, nonbullous emphysema. Single or multiple peripheral segmental wedge resections of the most destroyed areas of the lungs are performed with the use of stapling devices, in order to decrease hyperinflation and restore diaphragmatic function. Median sternotomy, videoendoscopy or anterior muscle sparing thoracotomies have been used as surgical approaches. The functional improvement after bilateral resections exceed those after a unilateral approach. LVRS has demonstrated its potential as an alternative to transplantation, and with growing experience, the indications for the procedure have been widened. In selected patients with peripheral lung cancer who have been considered unsuitable for a surgical resection, the combination of both tumour resection and LVRS has successfully been performed. In contrast to LVRS, laser surgery of the emphysematous lung has been abandoned in most institutions.  (+info)

Emphysematous lesions, inflammation, and fibrosis in the lungs of transgenic mice overexpressing platelet-derived growth factor. (8/1021)

Because of its expression pattern and its potent effects on mesenchymal cells, platelet-derived growth factor (PDGF) has been implicated as an important factor in epithelial-mesenchymal cell interactions during normal lung development and in the pathogenesis of fibrotic lung disease. To further explore the role of PDGF in these processes, we have developed transgenic mice that express the PDGF-B gene from the lung-specific surfactant protein C (SPC) promoter. Adult SPC-PDGFB transgenic mice exhibited lung pathology characterized by enlarged airspaces, inflammation, and fibrosis. Emphysematous changes frequently occurred throughout the lung, but inflammation and fibrotic lesions were usually confined to focal areas. The severity of this phenotype varied significantly among individual mice within the same SPC-PDGFB transgenic lineage. A pathology similar to that observed in adult mice was noted in lungs from transgenic mice as young as 1 week of age. Neonatal transgenic mice exhibited enlarged saccules and thickened primary septa. Results of these studies indicated that overexpression of PDGF-B induced distinct abnormalities in the developing and adult lung and led to a complex phenotype that encompassed aspects of both emphysema and fibrotic lung disease.  (+info)

Centrilobular emphysema | Article about centrilobular emphysema by The Free DictionaryCentrilobular emphysema | Article about centrilobular emphysema by The Free Dictionary
Looking for centrilobular emphysema? Find out information about centrilobular emphysema. A disorder marked by pulmonary inflation, primarily affecting the respiratory bronchioles and usually more severe in the upper lobes Explanation of centrilobular emphysema
Paediatria Croatica - Congenital lobar emphysema - case reportPaediatria Croatica - Congenital lobar emphysema - case report
A five month-old infant with congenital lobar emphysema is presented. Due to previously suspected diaphragmal hernia the infant underwent the surgery. Clinically, disorder was manifested with mild to severe respiratory symptoms. The indication for surgery was based on the radiological finding (hyperinflation of right upper lobe , as well as the computed tomography (herniation of the right lung to the left), lung scintigraphy (impaired perfusion of the right lung), bronchoscopy and bronchography the surgery, respectively. After lobectomy of upper right lobe the diagnosis was confirmed histopathologically as well ...
Congenital lobar emphysemaCongenital lobar emphysema
... (CLE), also known as congenital alveolar overdistension, is a developmental anomaly of the lower respiratory tract that is characterized by hyperinflation of one or more of the pulmonary lobes. Other terms for CLE include c
Congenital lobar emphysema definition | Drugs.comCongenital lobar emphysema definition | Drugs.com
Definition of congenital lobar emphysema. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
The Effect and Mechanism of Bronchoscopic Lung Volume Reduction by Endobronchial Valve in Korean Emphysema Patients - Full Text...The Effect and Mechanism of Bronchoscopic Lung Volume Reduction by Endobronchial Valve in Korean Emphysema Patients - Full Text...
The prevalence of chronic obstructive pulmonary disease (COPD) is high (13.4%). In addition, COPD ranked 10th among the causes of death in Korea, and rose to 7th in 2008. Airflow limitation of COPD is caused by a mixture of small airway disease (obstructive bronchiolitis) and parenchyma destruction (emphysema). Bronchodilator and anti-inflammatory drugs, such as corticosteroids are effective to obstructive bronchiolitis. However, these drugs are not effective to emphysema.. Lung volume reduction was devised to remove hyperinflated lung, and to function remaining lung. Surgical lung volume reduction showed improving survival in selected emphysema patients. However, surgical lung volume reduction have bee performed rarely due to significant surgery-related mortality. In this regard, non-surgical lung volume reduction methods have been developed. Of them, bronchoscopic lung volume reduction by endobronchial one-way valve is mostly used method and showed lower early complications than ...
BioGlue and Peri-strips in lung volume reduction surgery: pilot randomised controlled trial | Journal of Cardiothoracic Surgery...BioGlue and Peri-strips in lung volume reduction surgery: pilot randomised controlled trial | Journal of Cardiothoracic Surgery...
Lung Volume Reduction Surgery for emphysema has evolved over the last two decades since the original description by Brantigan [11]. Cooper and colleagues popularised the use of stapled excision of the emphysematous lung with good outcomes [1]. This was followed by a number of groups pursuing varied selection criteria and techniques with mixed results [4, 12-14]. However, the selection criteria and benefits of LVRS in end stage emphysema has been established in the National Emphysema Treatment Trial [2] with durable long term results in select group of patients [15].. One of the major complications of stapled LVRS is prolonged air leak which occurs in 50-90% of the patients [3]. A number of adjuncts to prevent air leak have been advocated which include bovine pericardium, Gore-Tex or autologous pleura [3, 6]. The buttressing of the staple line has been shown to reduce the duration of air leak and time to chest drain removal [6]. In our centre, the standard approach to Lung Volume Reduction ...
Lobar Emphysema 1 (Differential Diagnosis RDS) - Pediatric SurgeryLobar Emphysema 1 (Differential Diagnosis RDS) - Pediatric Surgery
Lobar Emphysema 1 (Differential Diagnosis RDS). Repeated chest radiographs in a newborn with progressive respiratory distress syndrome. Left picture: 3rd day of life. The upper right hemithorax is larger than its left counterpart. Notice the large intervals between the ribs. Center picture: 10th day of life. The difference between left and right becomes more pronounced; an absent lung structure in the right upper and middle hemithorax is recognizable. Right picture: 21st day of life: There is no heart shadow in the right hemithorax; an increase of the zone with absent lung structure is obvious and partially so in the left hemithorax, too. In contrast to the sudden onset of respiratory distress syndrome in most patients with congenital diaphragmatic hernia, respiratory distress syndrome or the signs of the respiratory system appear slowly during the neonatal period in many of the pathologies with a valve mechanism. In this case the pathology is a lobar emphysema of the right upper lobe. The lobe ...
Lung Reduction Surgery Risky For Certain Emphysema Patients - Columbia University Medical CenterLung Reduction Surgery Risky For Certain Emphysema Patients - Columbia University Medical Center
National Trial Yields First Scientific Evidence of Who Should Have Surgery-. New York, NY (Aug. 14, 2001) - The National Emphysema Treatment Trial (NETT), in which Columbia Presbyterian Medical Center of NewYork-Presbyterian Hospital is a major participant, has found that certain advanced emphysema patients benefit little from Lung Volume Reduction Surgery (LVRS) and are at unacceptable risk of death from the procedure. The NETT trial - a five-year, multicenter, randomized study designed to evaluate the role of LVRS in the treatment of severe emphysema - indicates that those patients who have severe lung obstruction with either limited ability to exchange gas while breathing or damage that is evenly distributed throughout their lungs should not undergo LVRS ...
Circulating endothelial stem cells are not decreased in pulmonary emphysema or COPD | ThoraxCirculating endothelial stem cells are not decreased in pulmonary emphysema or COPD | Thorax
Previous studies have suggested a role for an increased apoptosis of the endothelial cells in the pulmonary capillaries of the alveolar septa in the pathogenesis of human pulmonary emphysema.1 In animal models, circulating endothelial stem cells, characterised by the concomitant expression of CD34+, CD133 and vascular endothelial growth factor receptor 2 (VEGF-R2), may contribute to the repair of lung damage.2 However, it is unknown if a decrease in the blood of these stem cells contributes to the pathogenesis of pulmonary emphysema in humans. The aim of our study was to investigate by flow cytometry the number of total (CD34+) and endothelial stem (triple positive for CD34+/CD133/VEGF-R2) cells in the peripheral venous blood of current and former smokers of similar age, with or without pulmonary emphysema.. All the recruited subjects were free from concomitant diseases or drugs able to interfere with the number of circulating stem cells. Venous blood samples were obtained from 37 subjects (mean ...
An Outline of Pulmonary Function and Pulmonary Emphysema. | Annals of Internal Medicine | American College of PhysiciansAn Outline of Pulmonary Function and Pulmonary Emphysema. | Annals of Internal Medicine | American College of Physicians
Pulmonary emphysema is receiving increasing recognition as one of the countrys major health problems. The prevalence of bronchitis and pulmonary emphysema has been estimated as 13 per thousand, meaning that over 2,000,000 people in this country have these diseases. Unfortunately, many American physicians are not sufficiently aware of this problem nor do they understand the pathophysiology of this disease. A book such as Dr. Rosenman has attempted, designed to present in clear and simple terms the essence of pulmonary physiology and describe the abnormal physiology and treatment of pulmonary emphysema, could be a valuable aid to the medical student and ...
Three Cases of ALCAPA with Associated AnomaliesThree Cases of ALCAPA with Associated Anomalies
There are several potential issues that affect the treatment and diagnostic pattern of anomalous left coronary artery arising from the pulmonary artery. We report three cases of infants who presented with anomalous left coronary artery arising from the pulmonary artery with severe left ventricular dysfunction and severe mitral regurgitation along with associated anomalies. One patient had congenital lobar emphysema of the right midde lobe. Another patient had left main stem bronchus compression, collapse of basal segments of left lower lobe and panlobular emphysema in medial basal segment of right lower lobe. The third patient had cleft lip and palate. All patients underwent successful repair. The hemodynamic stability was compromised when the infant with congenital lobar emphysema had spontaneous pneumothorax after extubation and she needed an intercostal drainage. The infant with lung collapse had to be reintubated on the second day since she became hypoxic due to recollapse of the lung once the
Congenital Lobar Emphysema - The Clinical AdvisorCongenital Lobar Emphysema - The Clinical Advisor
Physician assistants and nurse practitioners use Clinical Advisor for updated medical guidance to diagnose and treat common medical conditions in daily practice.
Panacinar emphysema | Define Panacinar emphysema at Dictionary.comPanacinar emphysema | Define Panacinar emphysema at Dictionary.com
Panacinar emphysema definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
Netherlands 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation - Full Text View -...Netherlands 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation - Full Text View -...
Emphysema is a progressive, debilitating disease that affects nearly 3 million people in the United States or roughly one percent of the US population. The disease is characterized by destruction of lung tissue as a result of inflammation caused by exposure to noxious inhaled agents for extended periods. The most common cause of this condition is cigarette smoking, although genetic and occupational causes account for up to 10% of cases. Despite aggressive public health initiatives aimed at discouraging the use of cigarettes, smoking-related lung diseases remain a significant cause of disability and death in the United States. Currently there are 46 million smokers in the US. Due to the number of current and new smokers, emphysema is expected to remain a leading cause of morbidity and mortality in the United States for years to come.. Aeris has developed a novel bronchoscopic system for achieving the benefits of lung volume reduction without surgery. The Bronchoscopic Lung Volume Reduction (BLVR) ...
Assessment of multislice CT to quantify pulmonary emphysema function and physiology in a rat model<...Assessment of multislice CT to quantify pulmonary emphysema function and physiology in a rat model<...
TY - GEN. T1 - Assessment of multislice CT to quantify pulmonary emphysema function and physiology in a rat model. AU - Cao, Minsong. AU - Stantz, Keith M.. AU - Liang, Yun. AU - Krishnamurthi, Ganapathy. AU - Pressen, Robert G.. PY - 2005. Y1 - 2005. N2 - Purpose: The purpose of this study is to evaluate multi-slice computed tomography technology to quantify functional and physiologic changes in rats with pulmonary emphysema. Method: Seven rats were scanned using a 16-slice CT (Philips MX8000 IDT) before and after artificial inducement of emphysema. Functional parameters i.e. lung volumes were measured by non-contrast spiral scan during forced breath-hold at inspiration and expiration followed by image segmentation based on attenuation threshold. Dynamic CT imaging was performed immediately following the contrast injection to estimate physiology changes. Pulmonary perfusion, fractional blood volume, and mean transit times (MTTs) were estimated by fitting the time-density curves of contrast ...
JAIRO | Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography(審査報告)JAIRO | Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography(審査報告)
Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography(審査報告)Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography(審査報告) ...
National Emphysema Treatment Trial (NETT) | National Heart, Lung, and Blood Institute (NHLBI)National Emphysema Treatment Trial (NETT) | National Heart, Lung, and Blood Institute (NHLBI)
Learn about the National Emphysema Treatment Trial, a landmark study that clarified the risks and benefits of lung volume reduction surgery to treat emphysema.
Pulmonary Emphysema. | Annals of Internal Medicine | American College of PhysiciansPulmonary Emphysema. | Annals of Internal Medicine | American College of Physicians
This book, edited by two outstanding students of the clinical aspects of pulmonary emphysema, actually consists of a series of essays pertaining to various aspects of the syndrome.. The first half of the book (which, in the reviewers opinion, should be the second half) consists of a series of comprehensive and detailed discussions of the clinical management of pulmonary emphysema, as practiced by Dr. Barach and his group. There is no doubt that most of their beliefs are sound and based on long experience. However, one concept may need questioning. They strongly advocate using oxygen therapy for the hypoxic episodes ...
Pulmonary emphysema, CT scan - Stock Image C021/2971 - Science Photo LibraryPulmonary emphysema, CT scan - Stock Image C021/2971 - Science Photo Library
Pulmonary emphysema. Frontal computed tomography (CT) scan of a male patients chest showing severe emphysema in the left lung (right). There is a large area of trapped air (black) in the affected lung. Emphysema causes the tiny air sacs of the lungs to become damaged, leading to the walls between them breaking down. This causes large areas of trapped air and leads to a smaller surface area for gaseous exchange, restricting oxygen uptake by the blood. Enlarged air spaces bigger than 1 centimetre in diameter are known as bullae. Lung tissue in bullae may be completely destroyed. The main cause of emphysema is cigarette smoking. Symptoms include a cough and shortness of breath. Bullae may be surgically removed although there is no cure for emphysema. - Stock Image C021/2971
Pulmonary emphysema, X-ray - Stock Image C021/2974 - Science Photo LibraryPulmonary emphysema, X-ray - Stock Image C021/2974 - Science Photo Library
Pulmonary emphysema. Coloured frontal chest X-ray of a male patients chest showing severe emphysema in the left lung (right). There is a large area of trapped air (black) in the affected lung. Emphysema causes the tiny air sacs of the lungs to become damaged, leading to the walls between them breaking down. This causes large areas of trapped air and leads to a smaller surface area for gaseous exchange, restricting oxygen uptake by the blood. Enlarged air spaces bigger than 1 centimetre in diameter are known as bullae. Lung tissue in bullae may be completely destroyed. The main cause of emphysema is cigarette smoking. Symptoms include a cough and shortness of breath. Bullae may be surgically removed although there is no cure for emphysema. - Stock Image C021/2974
Parenchymal, bronchiolar, and bronchial measurements in centrilobular emphysema | ThoraxParenchymal, bronchiolar, and bronchial measurements in centrilobular emphysema | Thorax
Measurements of lung parenchyma, membranous bronchioles, and bronchial mucous gland hyperplasia were made on lungs from eight cases of pure centrilobular emphysema (CLE) and on five normal lungs. The lungs were fixed in formalin and inflated under partial vacuum at a standard transpulmonary pressure of +30 cm. H2O. The results obtained from the upper halves and the lower halves of the lungs were compared. The circulatory effects of the disease were measured by weighing the heart ventricles, by studying the small pulmonary arteries in microscopical sections, and by post-mortem arteriography. Whereas the parenchymal and internal surface areas destroyed by the emphysematous spaces were relatively moderate and localized, right ventricular hypertrophy was noted in most of the cases. In these cases bronchiolar stenoses were found scattered throughout the whole lung and there was a reduction in the number of these bronchioles, mainly in the upper halves of the lungs. In CLE ventilatory disturbances ...
Lobar emphysema: long-term imaging follow-up. - MyScienceWorkLobar emphysema: long-term imaging follow-up. - MyScienceWork
Lobar emphysema: long-term imaging follow-up.: In a retrospective study, the authors evaluated the initial and follow-up radiographs and ventilation perfusion (
Pulmonary Interstitial Emphysema Clinical Presentation: History and Physical ExaminationPulmonary Interstitial Emphysema Clinical Presentation: History and Physical Examination
Pulmonary interstitial emphysema (PIE) is a collection of gases outside of the normal air passages and inside the connective tissue of the peribronchovascular sheaths, interlobular septa, and visceral pleura. This collection develops as a result of alveolar and terminal bronchiolar rupture.
Risk factors and clinical outcomes of pulmonary interstitial emphysema in extremely low birth weight infants.Risk factors and clinical outcomes of pulmonary interstitial emphysema in extremely low birth weight infants.
OBJECTIVE: We studied the ante- and postnatal risk factors and clinical outcomes associated with pulmonary interstitial emphysema (PIE) in extremely low birth weight infants (ELBW, |1000 g at birth) in the present era of tocolytics, antenatal steroid
Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography<...Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography<...
TY - JOUR. T1 - Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography. AU - Sasaki, Mamoru. AU - Chubachi, Shotaro. AU - Kameyama, Naofumi. AU - Sato, Minako. AU - Haraguchi, Mizuha. AU - Miyazaki, Masaki. AU - Takahashi, Saeko. AU - Betsuyaku, Tomoko. PY - 2015/5/15. Y1 - 2015/5/15. N2 - Chronic cigarette smoke (CS) exposure provokes variable changes in the lungs, and emphysema is an important feature of chronic obstructive pulmonary disease. The usefulness of micro-computed tomography (CT) to assess emphysema in different mouse models has been investigated, but few studies evaluated the dynamic structural changes in a CS-induced emphysema mouse model. A novel micro-CT technique with respiratory and cardiac gating has resulted in high-quality images that enable processing for further quantitative and qualitative analyses. Adult female C57BL/6J mice were repeatedly exposed to mainstream CS, and micro-CT scans were performed at 0, 4, 12, and 20 wk. ...
Comparison of lung volume reduction surgery and physical training on health status and physiologic outcomes - A randomized...Comparison of lung volume reduction surgery and physical training on health status and physiologic outcomes - A randomized...
abstract = "Study objectives: In 1996, researchers in Sweden initiated a collaborative randomized study comparing lung volume reduction surgery (LVRS) and physical training with physical training alone. The primary end point was health status; secondary end points included survival and physiologic measurements. Design: After an initial 6-week physical training program, researchers patients were randomized to either LVRS (surgical group [SG]) with continued training for 3 months, or to continued training alone (training group [TG]) for 1 year. Setting: All seven thoracic surgery centers in Sweden. Patients: All patients in Sweden with severe emphysema fulfilling inclusion criteria for LVRS. Interventions: Patients randomized to surgery underwent a median sternotomy, except for a few patients in whom thoracotomy or video-assisted thoracoscopy were performed. In the TG, supervised physical training continued for 1 year; in the SG, supervised physical training continued for 3 months ...
Lung Volume Reduction Surgery for Chronic Obstructive Pulmonary Disease (COPD) | Columbia University Department of SurgeryLung Volume Reduction Surgery for Chronic Obstructive Pulmonary Disease (COPD) | Columbia University Department of Surgery
Lung Volume Reduction Surgery (LVRS) is a surgical procedure in which sections of severely damaged lung tissue are removed. By removing the most diseased tissue (up to 30% of the lung volume), the goal is to improve the residual lung function and respiratory mechanics in patients with end-stage emphysema. LVRS can be performed through either median sternotomy (open chest) or video-assisted minimally invasive technique. Studies show LVRS significantly improves quality of life, increases exercise capacity and even improves survival in carefully selected patients.
In vivo estimation of septal lung tissue volume and correlation with diffusing capacity in lung volume reduction surgery [4]<...In vivo estimation of septal lung tissue volume and correlation with diffusing capacity in lung volume reduction surgery [4]<...
TY - JOUR. T1 - In vivo estimation of septal lung tissue volume and correlation with diffusing capacity in lung volume reduction surgery [4]. AU - Takeda, Shin ichi. AU - Estrera, Aaron S.. AU - Hsia, Connie C W. PY - 2000. Y1 - 2000. UR - http://www.scopus.com/inward/record.url?scp=0033958894&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0033958894&partnerID=8YFLogxK. M3 - Article. C2 - 10612792. AN - SCOPUS:0033958894. VL - 119. SP - 191. EP - 192. JO - Journal of Thoracic and Cardiovascular Surgery. JF - Journal of Thoracic and Cardiovascular Surgery. SN - 0022-5223. IS - 1. ER - ...
Nishiyama, Yoshihiro - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORYNishiyama, Yoshihiro - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY
p,X-ray computed tomography (CT) has been used for diagnosis of pulmonary emphysema because it can reveal the morphology of low attenuation areas. Recently, 99mTc-Technegas imaging, one of several types of scintigraphic techniques, has been used for ventilation scintigraphy. Technegas scintigraphy was performed on 15 patients with pulmonary emphysema, and we compared the extent and degree of abnormal findings on Technegas scintigraphy with the extent of low attenuation areas shown by CT. We classified the findings of Technegas imaging into three grades, from mild to severe, according to the extent of peripheral irregularity and central hot spot formation. We also classified the findings of CT as centrilobular emphysema into three grades from mild to severe according to the extent of low attention areas in the peripheral lung fields. In 5 cases, CT and Technegas assessment resulted in equivalent diagnoses. In eight cases, Technegas images showed more detailed findings than CT images. In the two ...
Bronchoscopic lung volume reduction | European Respiratory SocietyBronchoscopic lung volume reduction | European Respiratory Society
The reintroduction in the mid-1990s of the surgical method originally conceived by Brantigan et al. [1], lung volume reduction, showed that under certain circumstances this treatment could improve the forced expiratory volume in one second (FEV1), indices of resting hyperinflation and quality of life [2].. However, three factors taken together have meant that lung volume reduction surgery (LVRS) has been useful in only a minority of patients. A significant proportion of patients, between one-quarter and one-third, fail to derive significant benefit from the procedure. This in itself might not matter if it were not for the second problem, which is that in large series, the mortality rate has been ≥4-5% [2-4]. While this risk might be acceptable if success were guaranteed, it is less appealing if it is not. Finally, in order to reduce mortality and morbidity, most groups impose safety criteria so that patients who are too disabled are not eligible for LVRS. Thus, in the present authors centre, ...
Chronic obstructive pulmonary disease: pulmonary emphysema and chronic bronchitis | Body DiseasesChronic obstructive pulmonary disease: pulmonary emphysema and chronic bronchitis | Body Diseases
A characteristic "barrel chest" is often seen in pulmonary emphysema. The appearance of the barrel chest is the result of lungs chronically overinflated with air causing the rib cage to stay partially expanded.. Two identifiers common in COPD are "blue bloater" and "pink puffer." A blue bloater describes a person with chronic bronchitis whose body responds to the increased obstruction by decreasing ventilation and increasing cardiac output. This leads to hypoxemia (oxygen deficiency in the blood) and polycythemia (excessive red blood cells). Together with retention of carbon dioxide, individuals show signs of cardiac failure and are described as blue bloaters.. A pink puffer describes a person with emphysema who has the decreased inability to oxygenate the blood. The body compensates with lower cardiac output and hyperventilation, causing a reddish complexion and a "puffing" appearance when breathing.. Diagnostic Procedures. A physical examination, chest x-ray, pulmonary function tests, arterial ...
Pulmonary EmphysemaPulmonary Emphysema
Emphysema is a chronic lung condition in which the air sacs (alveoli) may be destroyed, narrowed, collapsed, stretched, or overinflated. Pulmonary emphysema is part of a group of lung diseases called COPD. Heres what you need to know.
Touro | Pulmonary EmphysemaTouro | Pulmonary Emphysema
Emphysema is a chronic lung condition in which the air sacs (alveoli) may be destroyed, narrowed, collapsed, stretched, or overinflated. Pulmonary emphysema is part of a group of lung diseases called COPD. Heres what you need to know.
IJERPH | Free Full-Text | Cross-Sectional Analysis of the Utility of Pulmonary Function Tests in Predicting Emphysema in Ever...IJERPH | Free Full-Text | Cross-Sectional Analysis of the Utility of Pulmonary Function Tests in Predicting Emphysema in Ever...
Emphysema is largely an under-diagnosed medical condition that can exist in smokers in the absence of airway obstruction. We aimed to determine the sensitivity and specificity of pulmonary function tests (PFTs) in assessing emphysema using quantitative CT scans as the reference standard. We enrolled 224 ever-smokers (current or former) over the age of 40. CT of thorax was used to quantify the low attenuation area (% emphysema), and to measure the standardized airway wall thickness. PFTs were used individually and in combination to predict their ability to discriminate radiographic emphysema. Significant emphysema (|7%) was detected in 122 (54%) subjects. Twenty six (21%) emphysema subjects had no evidence of airflow obstruction (FEV1/FVC ratio 23% emphysema showed airflow obstruction. The sensitivity and specificity of spirometry for detecting radiographic emphysema were 79% and 75%, respectively. Standardized airway wall thickness was increased in subjects with airflow obstruction, but did not
Long-term Spa Therapy Prevents the Progressive Pathological Changes of the lung in Patients with Pulmonary Emphysema. -...Long-term Spa Therapy Prevents the Progressive Pathological Changes of the lung in Patients with Pulmonary Emphysema. -...
TY - JOUR. T1 - Long-term Spa Therapy Prevents the Progressive Pathological Changes of the lung in Patients with Pulmonary Emphysema.. AU - Ashida, Kouzou. PY - 2003. Y1 - 2003. M3 - Article. VL - 66. SP - 91. EP - 98. JO - J.Jpn Assoc Phys Med Balm Clim. JF - J.Jpn Assoc Phys Med Balm Clim. IS - (2). ER - ...
Pulmonary emphysema (COPD). Pulmonology: Diagnostic in Germany, Duesseldorf hospitals on BookingHealth.comPulmonary emphysema (COPD). Pulmonology: Diagnostic in Germany, Duesseldorf hospitals on BookingHealth.com
Pulmonary emphysema (COPD). Pulmonology: Diagnostic in Duesseldorf, Germany ✈. Prices on BookingHealth.com - booking treatment online!
Pulmonary emphysema (COPD). Pulmonology: Diagnostic in Switzerland, Winterthur hospitals on BookingHealth.comPulmonary emphysema (COPD). Pulmonology: Diagnostic in Switzerland, Winterthur hospitals on BookingHealth.com
Pulmonary emphysema (COPD). Pulmonology: Diagnostic in Winterthur, Switzerland ✈. Prices on BookingHealth.com - booking treatment online!
Pulmonary Emphysema Royalty Free Stock Image - Image: 22050446Pulmonary Emphysema Royalty Free Stock Image - Image: 22050446
Pulmonary Emphysema - Download From Over 66 Million High Quality Stock Photos, Images, Vectors. Sign up for FREE today. Image: 22050446
Severity analysis of pulmonary emphysema based on the comparison of expiratory and inspiratory states - Fingerprint - Keio...Severity analysis of pulmonary emphysema based on the comparison of expiratory and inspiratory states - Fingerprint - Keio...
Fingerprint Dive into the research topics of Severity analysis of pulmonary emphysema based on the comparison of expiratory and inspiratory states. Together they form a unique fingerprint. ...
Pulmonary emphysemaPulmonary emphysema
Here you will find medical specialists in the field Pulmonary emphysema. All listed physicians are specialists in their field and have been carefully selected for you according to the strict Leading Medicine guidelines. The experts are looking forward to your inquiry ...
Acute Bovine Pulmonary Emphysema and Edema - Respiratory System - Merck Veterinary ManualAcute Bovine Pulmonary Emphysema and Edema - Respiratory System - Merck Veterinary Manual
Learn about the veterinary topic of Acute Bovine Pulmonary Emphysema and Edema. Find specific details on this topic and related topics from the Merck Vet Manual.
Pathology of Emphysema - Dr Sampurna Roy MDPathology of Emphysema - Dr Sampurna Roy MD
Working with coal, whether as a miner or in other ways, results in an accumulation of coal or other dust in macrophages in and around respiratory bronchioles. Mild dilatation of respiratory bronchioles results, probably from atrophy of muscle. The lesion resembles centrilobular emphysema but differs in that the enlarged spaces are smaller and more regular, and inflammation of bronchioles is not apparent. Thus, the lesion is primarily distensive rather than destructive. The anatomic lesion is usually equated with a chest radiograph that shows small nodular densities, although the complete correlation has not been proved. The condition, also referred to as black lung, has been considered to cause severe disability. Contemporary evidence, however, suggests that simple coal pneumoconiosis causes only minor impairment of pulmonary function. When coal miners have severe chronic airflow obstruction, it is usually due to other forms of emphysema, notably tobacco-related centrilobular emphysema. Other ...
UMCG Enrolls First Patients in PneumRx RENEW Pivotal Trial for Treatment of Severe EmphysemaUMCG Enrolls First Patients in PneumRx RENEW Pivotal Trial for Treatment of Severe Emphysema
PneumRx, Inc., a leader in interventional pulmonology, announced today that University Medical Center Groningen has enrolled and treated the first patients in the FDA-approved RENEW pivotal trial to evaluate the RePneu Lung Volume Reduction Coil (LVRC). The RePneu LVRC, a minimally invasive medical implant designed to treat the symptoms of severe emphysema, is intended to improve lung function, exercise ability and quality of life for this underserved patient population.. (Logo: http://photos.prnewswire.com/prnh/20120514/SF06703LOGO) Dr. Dirk-Jan Slebos is the principal trial investigator at UMCG."There is no cure for severe emphysema, and patients have very few options available to relieve their symptoms," he said. "The LVRC is a very exciting technology that has shown great promise in European clinical studies. We have seen significant clinical improvements in treated patients, and we believe this is an important treatment option for many patients with severe emphysema." The RePneu LVRC is ...
Large Bronchogenic cyst Masquerading as Pericardial cyst and Causing Congenital lobar Emphysema | Journal of Cardiovascular...Large Bronchogenic cyst Masquerading as Pericardial cyst and Causing Congenital lobar Emphysema | Journal of Cardiovascular...
Abstract: Bronchogenic cysts are rare congenital lesions of the bronchial tree which are mostly asymptomatic. Rarely when the size is large it can compress on the adjacent structures in the mediastinum. We report a rare case of 10 month old baby presented with recurrent lower respiratory tract infection, was suspected to have a pericardial cyst on echocardiography. On further imaging it was confirmed to be a large bronchogenic cyst from the carina compressing on the left atrium and the left bronchus causing congenital lobar emphysema of the left lung. In view of compression of the adjacent structures patient was sent for surgery. Though congenital bronchogenic cysts involving pericardium and intracardiac tissues have been reported but mediastinal bronchogenic cysts compressing on left bronchus causing congenital lobar emphysema have rarely been reported. Key words: Bronchogenic cyst, Congenital lobar emphysema.. ...
CT findings of Budd-Chiari syndrome; low attenuation area and parenchymal enhancement of the liver<...CT findings of Budd-Chiari syndrome; low attenuation area and parenchymal enhancement of the liver<...
TY - JOUR. T1 - CT findings of Budd-Chiari syndrome; low attenuation area and parenchymal enhancement of the liver. AU - Majima, K.. AU - Ishibashi, T.. AU - Saitoh, H.. AU - Yamada, T.. AU - Tsuda, M.. AU - Tsuboi, M.. AU - Takahashi, S.. PY - 2001/1/1. Y1 - 2001/1/1. N2 - We performed triple phase enhanced CT examination in eight cases of Budd-Chiari syndrome. The examination items were the distribution of the low attenuation area in the liver on plain CT and parenchymal enhancement of the liver. Eight cases were classified into three patterns by the distribution of the low attenuation area. Parenchymal enhancement was variable by the degree of the obstruction of the hepatic vein and inferior vena cava.. AB - We performed triple phase enhanced CT examination in eight cases of Budd-Chiari syndrome. The examination items were the distribution of the low attenuation area in the liver on plain CT and parenchymal enhancement of the liver. Eight cases were classified into three patterns by the ...
Serum Proteins Associated with Emphysema Progression in Severe Alpha-1 Antitrypsin Deficiency<...Serum Proteins Associated with Emphysema Progression in Severe Alpha-1 Antitrypsin Deficiency<...
Beiko T, Janech MG, Alekseyenko AV, et al; for the QUANTUM-1 Investigators. Serum proteins associated with emphysema progression in severe alpha-1 antitrypsin deficiency.
UAB - School of Medicine - Medicine - UAB first in nation to test experimental therapy for emphysemaUAB - School of Medicine - Medicine - UAB first in nation to test experimental therapy for emphysema
Researchers at the University of Alabama at Birmingham injected a foam sealant into the lungs of a former smoker on Oct. 29, 2012, to treat his worsening emphysema. He was the first patient in the United States treated in a late-stage clinical trial of the AeriSeal System. The therapy, approved for use in parts of Europe and Israel, is undergoing investigation in the U.S. as a potential method of reducing lung volume in patients with severe emphysema.. Emphysema, a lung disease usually caused by smoking, damages air sacs in the lung called alveoli. The sacs fill with air that the body is unable to exhale, causing the lungs to expand. This in turn flattens the diaphragm, the primary muscle used for breathing. The flattened diaphragm is unable to function properly, making it extremely difficult for the individual to breathe. An estimated 4.9 million Americans have been diagnosed with emphysema.. A treatment known as lung volume reduction surgery has been employed to treat emphysema with some ...
Congenital lobar overinflation | Radiology Reference Article | Radiopaedia.orgCongenital lobar overinflation | Radiology Reference Article | Radiopaedia.org
Congenital lobar overinflation (CLO), previously called congenital lobar emphysema, is a congenital lung abnormality that results in progressive overinflation of one or more lobes of a neonates lung. On imaging, it classically presents on ches...
Semi-quantitative ventilation/perfusion scintigraphy and single-photon emission tomography for evaluation of lung volume...Semi-quantitative ventilation/perfusion scintigraphy and single-photon emission tomography for evaluation of lung volume...
TY - JOUR. T1 - Semi-quantitative ventilation/perfusion scintigraphy and single-photon emission tomography for evaluation of lung volume reduction surgery candidates. T2 - Description and prediction of clinical outcome. AU - Jamadar, David A.. AU - Kazerooni, Ella A.. AU - Martinez, Fernando J.. AU - Wahl, Richard L.. PY - 1999/7/29. Y1 - 1999/7/29. N2 - Ventilation/perfusion scans with single-photon emission tomography (SPET) were reviewed to determine their usefulness in the evaluation of lung volume reduction surgery (LVRS) candidates, and as a predictor of outcome after surgery. Fifty consecutive planar ventilation (99mTc-DTPA aerosol) and perfusion 99mTc-MAA) scans with perfusion SPET of patients evaluated for LVRS were retrospectively reviewed. Technical quality and the severity and extent of radiotracer defects in the upper and lower halves of the lungs were scored from visual inspection of planar scans and SPET data separately. An emphysema index (EI) (extent x severity) for the upper ...
NewYork-Presbyterian/Queens - Pulmonary EmphysemaNewYork-Presbyterian/Queens - Pulmonary Emphysema
COPD is a term that refers to a large group of lung diseases that can interfere with normal breathing. According to the American Lung Association, more than 12 million Americans have COPD, and an additional 12 million may have impaired lung function, suggesting it may be significantly underreported. As many as 24 million people may be affected. The two most common conditions of COPD are chronic bronchitis and emphysema.. The causes of COPD are not fully understood. It is generally agreed that the most important cause of chronic bronchitis and emphysema is cigarette smoking. Causes such as air pollution and occupational exposures may play a role, especially when combined with cigarette smoking. Heredity also plays a contributing role in some patients emphysema, and is especially important in a rare form due to alpha 1 anti-trypsin deficiency.. Patients with chronic bronchitis usually have a cough and sputum production for many years before they develop shortness of breath.. Patients with ...
Uptake Medicals BTVA has best safety profile per German Institute for Quality and Efficiency in Healthcare (IQWiG) - Uptake...Uptake Medical's BTVA has best safety profile per German Institute for Quality and Efficiency in Healthcare (IQWiG) - Uptake...
Berlin, Germany - Germanys Institute for Quality and Efficiency in Healthcare (IQWiG) recently published a commissioned study that assessed the available surgical and bronchoscopic lung volume reduction options for patients with severe pulmonary emphysema. Uptake Medicals recent randomized controlled trial (STEP-UP) of its Bronchoscopic Thermal Vapor Ablation (BTVA) InterVapor therapy was included in the German analysis.. The report included an analysis of patient relevant safety outcomes for each method analyzed. Of the bronchoscopic methods actively being used in Germany (vapor, EBV valves, IBV valves, and coils) vapor has the strongest safety profile. The comparison in Table 13 of the report concludes that coils and valves have "evidence [or] indication of harm to the treatment group as compared to the control group" in the category of "other adverse effects and complications of therapy." This is related to the high rates pneumothorax, hemoptysis, and other complications following ...
Pneumothorax and Pulmonary Interstitial Emphysema in the Newborn | Archives of Disease in ChildhoodPneumothorax and Pulmonary Interstitial Emphysema in the Newborn | Archives of Disease in Childhood
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Emphysema (See Pulmonary Emphysema) - Aloe ProductsEmphysema (See Pulmonary Emphysema) - Aloe Products
Order Aloe Products, Aloe Products for online shopping, Aloe Products for health, Aloe Products for sickness, Aloe Products for wealth, Aloe Products for skin care, Aloe Products for beauty, Aloe Products for nutrition, Aloe Products for weight management, Aloe Products for general health, Aloe Products for children, Aloe AProducts for Men, Aloe Products for Women
European Respiratory Society statement - Forskning - Region HovedstadenEuropean Respiratory Society statement - Forskning - Region Hovedstaden
α1-antitrypsin deficiency (AATD) is the most common hereditary disorder in adults. It is associated with an increased risk of developing pulmonary emphysema and liver disease. The pulmonary emphysema in AATD is strongly linked to smoking, but even a proportion of never-smokers develop progressive lung disease. A large proportion of individuals affected remain undiagnosed and therefore without access to appropriate care and treatment.The most recent international statement on AATD was published by the American Thoracic Society and the European Respiratory Society in 2003. Since then there has been a continuous development of novel, more accurate and less expensive genetic diagnostic methods. Furthermore, new outcome parameters have been developed and validated for use in clinical trials and a new series of observational and randomised clinical trials have provided more evidence concerning the efficacy and safety of augmentation therapy, the only specific treatment available for the pulmonary ...
Congenital cytomegalovirus infection associated with development of neonatal emphysematous lung disease -- Staunton et al. ...Congenital cytomegalovirus infection associated with development of neonatal emphysematous lung disease -- Staunton et al. ...
A 26-week-gestation infant developed cystic lung changes which required lobar resection at 6 weeks of age. Lung histology showed cytomegalovirus (CMV) inclusion bodies. The authors present the radiology and histology images of this case and review the literature regarding congenital CMV infection and cystic lung disease. Lung disease caused by CMV is typically a diffuse pneumonitis. This is the first reported case of congenital CMV infection causing emphysematous lung disease to develop in the neonatal period. The case raises awareness of CMV as a possible cause of cystic lung lesions in newborns. ...
Direct and Bone-Marrow Mediated Effects of Adipose Stem Cells in Emphysema - Indiana University School of MedicineDirect and Bone-Marrow Mediated Effects of Adipose Stem Cells in Emphysema - Indiana University School of Medicine
DESCRIPTION (provided by applicant): Pulmonary emphysema is a prevalent lung disease defined by permanent enlargement of airspaces, but also associated with systemic effects on organs that include the bone marrow and the cardiovascular system. Little is known about the mechanisms of systemic illness in emphysema and their impact, if any, on the lung disease. The lung destruction, clinically apparent after years of cigarette smoking has been attributed to protease-antiprotease imbalance, chronic inflammation, oxidative stress, and excessive alveolar cell death with loss of pulmonary capillaries that support the alveolar unit. We demonstrated that pluripotent cells contained in adipose stroma, called adipose stem or stromal cells promote capillary growth and limit ischemic tissue damage in models of acute skeletal muscle, myocardial, and cerebral ischemia and these salutary effects are mediated by angiogenic and anti-apoptotic paracrine factors. Given the feasibility of obtaining these stem cells, ...
Asthmatic Bronchitis And Early Emphysema - Asthmatic BronchitisAsthmatic Bronchitis And Early Emphysema - Asthmatic Bronchitis
The history holds the fundamental role in differentiating among asthma, chronic bronchitis, and emphysema. A private or family history of atopy, a history of seasonal worsening of disorder in response to some known environmental agent, perhaps seasonal, and marked variability in the severity of airflow obstruction, frequently with dramatic responsiveness to bronchodilator drugs, strongly support the identification of asthma. Exacerbation of wheezing by exposure to cold air or following the ingestion of a drug, and asthma variants, such as nocturnal cough sensitive to bronchodilator agents or exercise-induced asthma support the diagnosis of asthma. Cigarette smoking is a typical background factor in both chronic bronchitis and emphysema, and both diseases are infrequently found in the lack of this history. As new information collects on the pathogenesis, prevention, and treatment of emphysema, chronic bronchitis, and asthma, accurate identification is not unlikely to get increased value ...
Emphysema - Living With Emphysema | YourMedicalSourceEmphysema - Living With Emphysema | YourMedicalSource
Although many questions about emphysema remain unanswered, one thing is clear - quitting smoking can prevent the occurrence of emphysema and slow the disease. Other changes to your environment, such as avoiding smog, may also help prevent the development of emphysema or keep it from getting worse. Researchers continue to investigate the causes of and treatments for this disease.Things to consider include:
COPD(Chronic Obstructive Pulmonary Disease/Emphysema and other Chronic Illnesses)COPD(Chronic Obstructive Pulmonary Disease/Emphysema and other Chronic Illnesses)
Dr. Sharma was diagnosed with emphysema in 1994. He has first hand experienced the problems with depression, anxiety and life stress that often accompany emphysema. Below is a list of resources that Dr. Sharma, a Clinical Psychologist of 30 years practice has selected for people with emphysema/COPD and for their families and caregivers in order to offer you a perspective hopefully practical help. Check back often for the latest additions. If you dont see a topic listed, but would like to see it covered, please let Dr. Sharma know at his E-mail address, [email protected] DISCLAIMER: ...
IJMS | Free Full-Text | Profiling the Proteome of Exhaled Breath Condensate in Healthy Smokers and COPD Patients by LC-MS/MSIJMS | Free Full-Text | Profiling the Proteome of Exhaled Breath Condensate in Healthy Smokers and COPD Patients by LC-MS/MS
Three pools of exhaled breath condensate (EBC) from non-smokers plus healthy smokers (NS + HS, n = 45); chronic obstructive pulmonary disease (COPD) without emphysema (COPD, n = 15) and subjects with pulmonary emphysema associated with α1-antitrypsin deficiency (AATD, n = 23) were used for an exploratory proteomic study aimed at generating fingerprints of these groups that can be used in future pathophysiological and perhaps even clinical research. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was the platform applied for this hypothesis-free investigation. Analysis of pooled specimens resulted in the production of a
Kuros and Aeris Sign Licensing Agreement - RedorbitKuros and Aeris Sign Licensing Agreement - Redorbit
Switzerland-based Kuros Biosurgery has granted US-based Aeris Therapeutics an exclusive license in the field of lung volume reduction to certain patent rights Kuros exclusively licensed from the American Red Cross that cover the delivery of certain drugs in a fibrin sealant. In return for the license, Kuros will receive upfronts, milestones and royalties on the sale of Aeriss lead product, the AeriSeal biologic lung volume reduction (BLVR) system, a novel investigational emphysema treatment. Aeris is currently preparing for the initiation of Phase III clinical trials for the AeriSeal BLVR system. David Dove, CEO of Aeris, said: "The licensing of this IP from Kuros is an important step in the continued development of our unique BLVR system. We believe that BLVR has the potential to offer patients suffering from emphysema a treatment option that can alleviate their symptoms of shortness of breath and improve quality of life.". ...
Emphysema - catch, body, causes, What Is Emphysema?Emphysema - catch, body, causes, What Is Emphysema?
Air reaches the lungs through a series of ever-smaller tubes. First air passes through the trachea (TRAY-kee-a), which is the large windpipe from the throat down the neck. Then the trachea branches into smaller tubes called the bronchi (BRONG-ky), then into even smaller bronchi called bronchioles (BRONG-kee-olz) that branch still further deep into the lungs. The bronchioles end in tiny air sacs called alveoli. It is in the alveoli that the transfer of oxygen into the bloodstream and of carbon dioxide out of the bloodstream occurs. In emphysema, the bronchi and bronchioles are inflamed and continually swollen and clogged. This causes the alveoli to swell. These fragile air sacs burst and merge together. This damage to the alveoli makes it more difficult for the transfer of oxygen and carbon dioxide to take place. People with emphysema have difficulty breathing. It is usually caused by cigarette smoking, or a severe form of bronchitis called chronic obstructive bronchitis. Very often, a ...
Causes of emphysemaCauses of emphysema
Cigarette smoking is the major cause of emphysema. Among other causes of emphysema are industrial pollutants, aerosol sprays, non-tobacco smoke.
EmphysemaEmphysema
If you recognize any of the symptoms of emphysema and you fit under any category of the possible risk factors, you should speak with your physician immediately. Your doctor will most likely perform a fairly simple test known as spirometry, which tests how well a person can breathe. The test generally consists of blowing into a mouth piece connected to a device that will measure your lung capacity.. The doctor can also listen to your lungs with a stethoscope, or use x-rays or computerized tomography (CT) scans to view the lungs. However, these tests dont always indicate the possible development of emphysema, even though it may be present. Typically, these tests, in conjunction with a spirometry are enough to be indicative of the development of emphysema during its early stages.. ...
Edgardo S. Salcedo, M.D. for UC Davis HealthEdgardo S. Salcedo, M.D. for UC Davis Health
Henderson AC, Ingenito EP, Salcedo ES, Moy ML, Reilly JJ, Lutchen KR. Dynamic lung mechanics in late-stage emphysema before and after lung volume reduction surgery. Respir Physiol Neurobiol. 2007 Mar 15;155(3):234-42.. Snow BD, Salcedo ES, Greenholz SK, Galante JM. Traumatic Tension Chylothorax in a Child: A Case Report. J Pediatr Surg Case Rep. 2015 Apr; 3 (4):163-165.. Jacobs BG, Turnipseed SD, Nguyen AN, Salcedo ES, Nishijima DK. Acute Medical Diagnoses are Common in "Found Down" Adult Patients Presenting to the Emergency Department as Trauma. J Emerg Med. 2015 Jun 2.pii:S0736-4679(15)00274-7.. Hight RA, Salcedo ES, Martin SP, Cocanour CS, Utter GH, Galante JM. Level I Academic Trauma Center Integration as a Model for Sustaining Combat Surgical Skills: The Right Surgeon in the Right Place for the Right Time. J Trauma Acute Care Surg. 2015 Jun; 78 (6).. Dhillon TS, Galante JM, Salcedo ES, Utter GH. The anatomic severity of chest wall injuries does not predict post-recovery pulmonary symptoms: ...
Validity of apparent diffusion coefficient hyperpolarized He-3-MRI using MSCT and pulmonary function tests as referencesValidity of apparent diffusion coefficient hyperpolarized He-3-MRI using MSCT and pulmonary function tests as references
article{7013d42c-c06e-457e-b773-bdc1b35ccc3b, abstract = {Purpose: To compare apparent diffusion coefficient (ADC) measurements from hyperpolarized (HP) helium (He-3)-magnetic resonance imaging (MRI) with quantitative data from multislice Computed Tomography (CT) (MSCT) of the whole lungs and pulmonary function tests (PFT). Materials and methods: Twenty-seven subjects, 22 with established emphysema and 5 with preclinical emphysema defined by PFT criteria, were examined with Hp He-3-MRI and MSCT. Mean age was 55 (+/- 12) years, 18 female and 9 male. Mean ADC from He-3-MRI was compared with emphysema index (EI), 15th percentile and mean lung density (MLD) values from MSCT. Both mean ADC and MSCT data were compared to PFT, especially percent of predicted diffusing capacity of carbon monoxide (%predicted DLCO), using Pearsons correlation test. Results: Mean ADC and standard deviation values were 0.392 +/- 0.119 cm(2)/s for the established emphysema group and 0.216 +/- 0.046 for the pre-clinical ...
How tobacco can Save You Time, Stress, and Money.How tobacco can Save You Time, Stress, and Money.
Quickly information on emphysema Here are a few important points about emphysema. Far more depth and supporting info is in the human body of this text. Most scenarios of COPD, and for that reason emphysema, are attributable to cigarette smoking. Emphysema is rarely because of a congenital issue often known as α1-antitrypsin deficiency, for which Theres a lab check. Shortness of breath and cough are the most crucial signs or symptoms of emphysema. Physicians diagnose COPD and emphysema with lung functionality tests emphysema demographics to evaluate lung ability. Spirometry is Utilized in prognosis - to evaluate the volume of air a client can blow out in a single next after a deep breath ...
2014 ICD-9-CM Diagnosis Code 518.1 : Interstitial emphysema2014 ICD-9-CM Diagnosis Code 518.1 : Interstitial emphysema
Free, official information about 2014 (and also 2015) ICD-9-CM diagnosis code 518.1, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
Rapidly Progressive Pulmonary Apical Fibrosis and Parenchymal Destruction in a Patient with Ankylosing SpondylitisRapidly Progressive Pulmonary Apical Fibrosis and Parenchymal Destruction in a Patient with Ankylosing Spondylitis
Pulmonary apical fibrosis is a rare complication of ankylosing spondylitis (AS). The essential characteristics of this lesion are its very slow progression and frequently asymptomatic nature. Herein, we are presenting a patient with AS who rapidly developed pulmonary apical fibrosis in a 3-year period despite decreased musculoskeletal pains. The 60-year-old male applied with complaints of progressively increasing cough in the recent two years, dyspnea, and fatigue. He had no chronic disease except AS. He had no continuous medication except nonsteroid anti-inflammatory drugs for 2-3 days monthly since his musculoskeletal pains decreased in the recent years. His physical examination revealed reduced breath sounds in the upper zones of the right lung. Chest X-ray revealed increased diffuse opacity in the upper zones of the right lung. Thoracic high-resolution computed tomography showed a consolidation accompanied with traction bronchiectases compatible with chronic fibrosis in the upper lobe of the right
CT Scan says (radiologist) Mild Emphysema Pulmonologist says NOCT Scan says (radiologist) Mild Emphysema Pulmonologist says NO
What a dilemma ! I am so confused I was sure a Radiologist makes a diagnosis ( Impression) it may as well be set in stone then went to Pulmonary MD # …
V/Q mismatch - emphysemaV/Q mismatch - emphysema
Emphysema is defined by destruction of airways distal to the terminal bronchioloe.. Physiology of emphysema involves gradual destruction of alveolar septae and of the pulmonary capillary bed, leading to decreased ability to oxygenate blood. The body compensates with lowered cardiac output and hyperventilation. Thus, V/Q mismatch results in relatively limited blood flow through a fairly well oxygenated lung with normal blood gases and pressures in the lung, in contrast to the situation in bronchitis patients who are referred to as "blue bloaters." Because of low cardiac output, however, the rest of the body suffers from tissue hypoxia and pulmonary cachexia. Eventually, these patients develop muscle wasting and weight loss and are identified as "pink puffers.". (In bronchitis, the reverse situation is the case. The body compensates to mucus clogged airways and a relatively intact alveolar bed with a decrease in ventilation and an increase in cardiac output, which worsens baseline ...
Pocket Reduction Surgery | The Dental ClinicPocket Reduction Surgery | The Dental Clinic
What does pocket reduction surgery involve?. Before recommending treatment or performing any procedure, the dentist will perform thorough visual and x-ray examinations in order to assess the condition of the teeth, gums and underlying bone. Pocket reduction surgery may be performed under local or general anesthetic depending on the preferences of the patient.. The gums will be gently pulled back from the teeth and bacteria and calculus (tartar) will be eliminated. Scaling and root planing will generally be required to fully remove the ossification (tartar) from the surface of the tooth root. If the root is not completely smooth, a planing procedure will be performed to ensure that when the gums do heal, they will not reattach to rough or uneven surfaces.. The final part of the surgery is usually the administration of an antimicrobial liquid to eliminate any remaining bacteria and promote healing. The gum is then sutured with tiny stitches that are left in place for 5-10 days.. Though the gums ...
Emphysema | Central Arkansas LungEmphysema | Central Arkansas Lung
There is no cure for emphysema and the damage to the lung tissue cannot be reversed, but it is possible to prevent the condition from getting worse and to improve symptoms.. Initially, the treatment of emphysema should address the cause of the condition. For example, quitting smoking should be a priority if you smoke to prevent further damage to the lungs.. Additionally, there are medications that can help to reduce shortness of breath and allow you to carry out your daily activities as normal. Bronchodilator and steroid medications can be administered in an inhaler device so that the medication is directly specifically to the airways. Its important that you understand how to use an inhaler correctly in order to benefit from the medication. If you need help with this, we can demonstrate how to use an inhaler in the clinic.. You may also need other treatment. Antibiotics can help to fight off a bacterial infection of the respiratory system and some people also need oxygen to help with breathing ...
Recommended post: How could Amy Winehouse have emphysema? - Terra SigillataRecommended post: How could Amy Winehouse have emphysema? - Terra Sigillata
When I first heard that 24-year-old British singer-songwriter Amy Winehouse was hospitalized with early stage emphysema I said "what?" DrugMonkey, a drug-abuse research colleague, has a terrific post up now on the link between Winehouses crack cocaine use, possible genetic predisposition, and the emergence of early-onset emphysema.. While sad to see a very young person so afflicted, I tend to be fascinated scientifically by these odd medical cases involving natural products - often drugs of abuse.. Im also particularly impressed by Amy Winehouses tremendous vocal talents and songwriting abilities. Her jazz and soul vocal style has been described as reminiscent of legends like Sara Vaughn and I find it striking that her songs are considered pop music in 2008. But like many incredible musicians before her, Winehouse at 24 has more legal problems, drug abuse issues and violent, self-destructive behaviors than most people might accumulate in several dozen lives. I echo DrugMonkeys call to ...
Fabeha Fazal, Ph.D. - University of Rochester Medical CenterFabeha Fazal, Ph.D. - University of Rochester Medical Center
A major focus of research in my laboratory deals with understanding the role and regulation of actin-myosin interactions in endothelial cell (EC) inflammation, permeability, and apoptosis, especially in the settings of acute and chronic lung injury. We study pathways of EC inflammation, barrier dysfunction and apoptosis on the molecular, cellular, and animal level. We have uncovered novel and previously unrecognized role of actin cytoskeleton and non-muscle myosin light chain kinase (nmMLCK) in the regulation of cytoplasmic trafficking of NF-k? for its nuclear import to cause EC inflammation associate with intravascular coagulation and sepsis. More recently we have been involved in the identification of endoplasmic reticulum (ER) stress as an important determinant of EC inflammation and permeability associated with acute lung injury (ALI). In our most recent work, we have focused on understanding the role of nmMLCK in the pathogenesis of pulmonary emphysema caused by cigarette smoke (CS). The ...
Inhibition of Elastase-Pulmonary Emphysema in Dominant-Negative MafB Transgenic MiceInhibition of Elastase-Pulmonary Emphysema in Dominant-Negative MafB Transgenic Mice
1. Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA. et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007;176:532-55 2. Sharafkhaneh A, Hanania NA, Kim V. Pathogenesis of emphysema: from the bench to the bedside. Proc Am Thorac Soc. 2008;5:475-7 3. Lopez AD, Shibuya K, Rao C, Mathers CD, Hansell AL. et al. Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J. 2006;27:397-412 4. Shapiro SD. The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999;160:S29-32 5. Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J. 2003;22:672-88 6. Shapiro SD. COPD unwound. N Engl J Med. 2005;352:2016-9 7. Machiya J, Shibata Y, Yamauchi K, Hirama N, Wada T. et al. Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure. Am J ...
In her own words: living with emphysema | Medical City DallasIn her own words: living with emphysema | Medical City Dallas
Learn more about In her own words: living with emphysema at Medical City Dallas Sandy, a 50-year-old woman, is married with three grown children. She started smoking...
CPE | Encyclopedia.comCPE | Encyclopedia.com
CPE Certificate of Physical Education• (USA) Certified Property Exchanger• Med. chronic pulmonary emphysema• College of Physical Education• Law Common Professional Examination• Congrès du peuple européen (French: Congress of European People)• contractor performance evaluation• Microbiol. cytopathic effect Source for information on CPE: The Oxford Dictionary of Abbreviations dictionary.
Centriacinar emphysema. Contact radiograph of an inflat | Open-iCentriacinar emphysema. Contact radiograph of an inflat | Open-i
Centriacinar emphysema. Contact radiograph of an inflated fixed lung demonstrating low attenuation in the centriacinar area (arrow). Note that distances between
The genetics of chronic obstructive pulmonary disease | Respiratory Research | Full TextThe genetics of chronic obstructive pulmonary disease | Respiratory Research | Full Text
The first genetic association studies in the 1970s used the small number of genetic polymorphisms that were then known: largely blood group antigens [45]. Subsequently, candidate genes thought to be involved in the pathophysiology of COPD have been examined. For instance, polymorphisms in the proteins that protect the lungs against proteolytic attack have been assessed. A polymorphism that predisposed smokers to develop COPD (Taq-1 G→A) [46] was detected by the restriction enzyme Taq-1 in the 3 non-coding region of the α1-antitrypsin gene. The Taq-1 (G→A) allele, conferring the absence of this Taq-1 site, was present in 18% of a population of emphysema patients, but in only 5% of blood donor control subjects. This association was confirmed by a second European group [47]; further studies revealed that the polymorphism was in a regulatory sequence, and that the Taq-1 (G→A) allele reduced the production of α1-antitrypsin in response to the inflammatory cytokine interleukin-6 (IL-6) [48]. ...
PapilledemaPapilledema
Swyer-James syndromeSwyer-James syndrome
Fog feverFog fever
ElastaseElastase
Obstructive lung diseaseObstructive lung disease
TracheotomyTracheotomy
José Piñera CarvalloJosé Piñera Carvallo
Jakub ChlebowskiJakub Chlebowski
Lumleian LecturesLumleian Lectures
Enrico MartinelliEnrico Martinelli
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Ivan LessaIvan Lessa
Passive smokingPassive smoking
Word senseWord sense
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Ageratina adenophoraAgeratina adenophora
Histoplasma capsulatumHistoplasma capsulatum
SerpinSerpin
Aurelio BaldorAurelio Baldor
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Air pollutionAir pollution
HOXB2HOXB2
William DeVriesWilliam DeVries
SilicosisSilicosis
BarotraumaBarotrauma
BiolungBiolung
Progressive diseaseProgressive disease
ABHD2ABHD2
BullectomyBullectomy
Occupational lung diseaseOccupational lung disease
Mary AstorMary Astor
InhalationInhalation
ടോൺസിലൈറ്റിസ് - വിക്കിപീഡിയടോൺസിലൈറ്റിസ് - വിക്കിപീഡിയ
Alpha-1 antitrypsinAlpha-1 antitrypsin
SpirometrySpirometry
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
BronchusBronchus
InfluenzaInfluenza
Template:Respiratory pathologyTemplate:Respiratory pathology
ThoracotomyThoracotomy
اکسیژن - ویکی‌پدیا، دانشنامهٔ آزاداکسیژن - ویکی‌پدیا، دانشنامهٔ آزاد
Non-small-cell lung carcinomaNon-small-cell lung carcinoma
OxygenOxygen
BronchitisBronchitis
Chest tubeChest tube
Trauma centerTrauma center
TobaccoTobacco
කොවිඩ්-19 - විකිපීඩියාකොවිඩ්-19 - විකිපීඩියා
CT scanCT scan
Respiratory tractRespiratory tract
Respiratory arrestRespiratory arrest
ElastinElastin
Shortness of breathShortness of breath
Health effects of tobaccoHealth effects of tobacco
Exercise-induced bronchoconstrictionExercise-induced bronchoconstriction
ThoracentesisThoracentesis
Acute respiratory distress syndromeAcute respiratory distress syndrome
Air pollutionAir pollution
Medical signMedical sign
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Pulmonary EmphysemaEmphysemaPancreatic Elastasealpha 1-Antitrypsin DeficiencySubcutaneous Emphysemaalpha 1-AntitrypsinLungMatrix Metalloproteinase 12Pulmonary AlveoliMediastinal EmphysemaRespiratory Function TestsSmokeHeliumPulmonary Disease, Chronic ObstructivePneumonectomyVasculitis, Leukocytoclastic, CutaneousElastinPanniculitisSmokingTomography, X-Ray ComputedBronchoalveolar Lavage FluidForced Expiratory VolumePulmonary FibrosisLung CompliancePneumoniaDisease Models, AnimalLung DiseasesBronchiMice, Inbred C57BLTobaccoCoughLung Diseases, ObstructivePubMedPeriodicals as TopicBooksInternal MedicineEvidence-Based MedicineWeight GainAir SacsSkatoleVeterinary MedicineHypertension, PulmonarySyndromePulmonary MedicineDyspneaSpirometryTelepathologyUrologyBronchitis, ChronicBronchitisNephrology
What is pulmonary emphysema?What is pulmonary emphysema?
Pulmonary Emphysema Royalty Free Stock Image - Image: 22050446Pulmonary Emphysema Royalty Free Stock Image - Image: 22050446
Impact of exacerbations on emphysema progression in chronic obstructive pulmonary disease. - PubMed - NCBIImpact of exacerbations on emphysema progression in chronic obstructive pulmonary disease. - PubMed - NCBI
Pulmonary Emphysema. | Annals of Internal Medicine | American College of PhysiciansPulmonary Emphysema. | Annals of Internal Medicine | American College of Physicians
Pulmonary Emphysema | INTEGRISPulmonary Emphysema | INTEGRIS
Pulmonary emphysema | BMJ Evidence-Based MedicinePulmonary emphysema | BMJ Evidence-Based Medicine
Pulmonary emphysemaPulmonary emphysema
Pulmonary emphysema, X-ray - Stock Image C021/2974 - Science Photo LibraryPulmonary emphysema, X-ray - Stock Image C021/2974 - Science Photo Library
Acute Bovine Pulmonary Emphysema and Edema - Respiratory System - Merck Veterinary ManualAcute Bovine Pulmonary Emphysema and Edema - Respiratory System - Merck Veterinary Manual
pulmonary emphysema - Humpath.com - Human pathologypulmonary emphysema - Humpath.com - Human pathology
Risk factors and clinical outcomes of pulmonary interstitial emphysema in extremely low birth weight infants.Risk factors and clinical outcomes of pulmonary interstitial emphysema in extremely low birth weight infants.
Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema...Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema...
Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary diseaseArterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease
Quantitative analysis of pulmonary emphysema using isotropic Gaussian Markov random fields - ePrints SotonQuantitative analysis of pulmonary emphysema using isotropic Gaussian Markov random fields - ePrints Soton
FastStats - Chronic Lower Respiratory DiseaseFastStats - Chronic Lower Respiratory Disease
Pulmonary interstitial emphysema - WikipediaPulmonary interstitial emphysema - Wikipedia
Combined pulmonary fibrosis and emphysema - WikipediaCombined pulmonary fibrosis and emphysema - Wikipedia
PULMONARY EMPHYSEMA - Symptoms, Diagnosis &...PULMONARY EMPHYSEMA - Symptoms, Diagnosis &...
CiteSeerX - Pulmonary emphysema Chronic obstructiveCiteSeerX - Pulmonary emphysema Chronic obstructive
Pulmonary Interstitial Emphysema: Pearls, Background, PathophysiologyPulmonary Interstitial Emphysema: Pearls, Background, Pathophysiology
Imaging in Pulmonary Interstitial Emphysema: Practice Essentials, RadiographyImaging in Pulmonary Interstitial Emphysema: Practice Essentials, Radiography
Could I have Emphysema? - Chronic Obstructive Pulmonary Disease (COPD) - MedHelpCould I have Emphysema? - Chronic Obstructive Pulmonary Disease (COPD) - MedHelp
Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in ratsRetinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
Molecular Expressions Microscopy Primer: Specialized Microscopy Techniques - Phase Contrast Photomicrography Gallery -...Molecular Expressions Microscopy Primer: Specialized Microscopy Techniques - Phase Contrast Photomicrography Gallery -...
Pulmonary Emphysema - AHealthyMe - Blue Cross Blue Shield of MassachusettsPulmonary Emphysema - AHealthyMe - Blue Cross Blue Shield of Massachusetts
Acute bovine pulmonary emphysema-edema - definition of acute bovine pulmonary emphysema-edema by The Free DictionaryAcute bovine pulmonary emphysema-edema - definition of acute bovine pulmonary emphysema-edema by The Free Dictionary
What is the role of conventional ventilation (CMV) in the prevention of pulmonary interstitial emphysema (PIE)?What is the role of conventional ventilation (CMV) in the prevention of pulmonary interstitial emphysema (PIE)?
PULMONARY FIBROSIS AND EMPHYSEMA* | Annals of Internal Medicine | American College of PhysiciansPULMONARY FIBROSIS AND EMPHYSEMA* | Annals of Internal Medicine | American College of Physicians
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. - PubMed - NCBISmall-airway obstruction and emphysema in chronic obstructive pulmonary disease. - PubMed - NCBI
Surgical resection for pulmonary interstitial emphysema in the newborn infant.Surgical resection for pulmonary interstitial emphysema in the newborn infant.
Emphysema and bronchiectasis in COPD patients with previous pulmonary | COPDEmphysema and bronchiectasis in COPD patients with previous pulmonary | COPD
What is pulmonary interstitial emphysema (PIE) in babies? | Emphysema - SharecareWhat is pulmonary interstitial emphysema (PIE) in babies? | Emphysema - Sharecare
Pulmonary Emphysema Summary Report | CureHunterPulmonary Emphysema Summary Report | CureHunter
Article - Sponge Lung: Pulmonary edema superimposed on emphysemaArticle - Sponge Lung: Pulmonary edema superimposed on emphysema
Influence of emphysema distribution on pulmonary function parameters in COPD patientsInfluence of emphysema distribution on pulmonary function parameters in COPD patients
Gross Fixation Methods Used in the Study of Pulmonary Emphysema | ThoraxGross Fixation Methods Used in the Study of Pulmonary Emphysema | Thorax
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Pulmonary EmphysemaEmphysemaPancreatic Elastasealpha 1-Antitrypsin DeficiencySubcutaneous Emphysemaalpha 1-AntitrypsinLungMatrix Metalloproteinase 12Pulmonary AlveoliMediastinal EmphysemaRespiratory Function TestsSmokeHeliumPulmonary Disease, Chronic ObstructivePneumonectomyVasculitis, Leukocytoclastic, CutaneousElastinPanniculitisSmokingTomography, X-Ray ComputedBronchoalveolar Lavage FluidForced Expiratory VolumePulmonary FibrosisLung CompliancePneumoniaDisease Models, AnimalLung DiseasesBronchiMice, Inbred C57BLTobaccoCoughLung Diseases, ObstructivePubMedPeriodicals as TopicBooksInternal MedicineEvidence-Based MedicineWeight GainAir SacsSkatoleVeterinary MedicineHypertension, PulmonarySyndromePulmonary MedicineDyspneaSpirometryTelepathologyUrologyBronchitis, ChronicBronchitisNephrology
COPDCentrilobular emphysemaLobar emphysemaSevereFibrosisAlveolarDiagnosisComputed tomographyLungsDiseaseEmbolismTissueChestShortnessPathologyProgressionSeveritySymptomsNational Emphysema Treatment TrialRehabilitationFunctionUpper lobe emphysemaCombined Pulmonary Fibrosis and EmphysemaShortness of BreCause of emphysemaDiagnosis of emphysemaInterstitial Lung DiDiffuseCPFEObstructiveCentriacinar EmphysemaSymptoms of pulmonary emphysemaPathophysiologySign of emphysemaSubcutaneous emphysemaAirflowLobeOccursSacsIdiopathicDevelopment of pulmonaryMortalityCigaretteSmokersOnsetRadiographicPatients with advanced emphysemaPeople with pulmonaryPrevalencePattern of pulmonary
COPD11
Centrilobular emphysema1
Lobar emphysema1
Severe11
  • Functional and radiological findings have showed that these patients are suffering from severe breathlessness, but whose pulmonary functional tests revealed no signs of obstruction, normal static lung volumes, and depressed DLco, most with a history of smoking . (scirp.org)
  • The RePneu LVRC, a minimally invasive medical implant designed to treat the symptoms of severe emphysema, is intended to improve lung function, exercise ability and quality of life for this underserved patient population. (mdtmag.com)
  • There is no cure for severe emphysema, and patients have very few options available to relieve their symptoms," he said. (mdtmag.com)
  • We have seen significant clinical improvements in treated patients, and we believe this is an important treatment option for many patients with severe emphysema. (mdtmag.com)
  • The RENEW trial is enrolling patients throughout the US and Europe who have been clinically diagnosed with severe emphysema and are experiencing increasing difficulty with simple daily tasks despite optimal medical management. (mdtmag.com)
  • Though RePneu LVRC is investigational in the United States and not yet approved for commercial use by the FDA, the device has been used in Europe - in clinical trials and commercially - for the treatment of severe emphysema since 2008. (mdtmag.com)
  • This paper utilizes trial data to identify the predictors of HRQoL in patients with severe emphysema, and subsequently estimates the impact of a new treatment on HRQoL (measured by utilities). (uzh.ch)
  • Conclusions: Coils and SoC resulted in statistically significant improvements in HRQoL compared to SoC alone in patients with severe emphysema. (uzh.ch)
  • The 17 NETT clinical centers studied more than 1,200 patients who had severe emphysema. (nih.gov)
  • The NETT clarified the short-term and long-term risks and benefits of LVRS as a treatment for severe emphysema. (nih.gov)
  • A disorder marked by pulmonary inflation, primarily affecting the respiratory bronchioles and usually more severe in the upper lobes. (thefreedictionary.com)
Fibrosis4
Alveolar6
  • Pulmonary emphysema is defined as the permanent enlargement of airspaces distal to the terminal bronchioles and the destruction of the alveolar walls. (medscape.com)
  • To interpret these results, we established a novel simulation model and found that not only enlargement of preexisting low-attenuation areas but also coalescence of adjoining low-attenuation areas due to alveolar wall destruction caused emphysema progression in patients with exacerbations. (nih.gov)
  • Pulmonary emphysema, a significant global health problem, is characterized by a loss of alveolar structures. (jci.org)
  • Because VEGF is a trophic factor required for the survival of endothelial cells and is abundantly expressed in the lung, we hypothesized that chronic blockade of VEGF receptors could induce alveolar cell apoptosis and emphysema. (jci.org)
  • These findings suggest that VEGF receptor signaling is required for maintenance of the alveolar structures and, further, that alveolar septal cell apoptosis contributes to the pathogenesis of emphysema. (jci.org)
  • Regional emphysema severity was quantified in each tissue sample using the mean linear intercept (Lm) between alveolar walls from micro-CT scans. (biomedcentral.com)
Diagnosis3
Computed tomography5
Lungs1
  • Researchers identified two characteristics-emphysema mostly in the upper lobes of the lungs and low exercise capacity-that helped predict which patients would benefit from surgery. (nih.gov)
Disease13
Embolism1
Tissue1
  • Emphysema causes irreversible damage to delicate lung tissue, leading to shortness of breath and even feelings of suffocation that result in reduced quality of life. (mdtmag.com)
Chest1
Shortness1
  • There's little as frightening and frustrating as the feeling of not getting enough air, and this shortness of breath, can turn normal activities into major obstacles for people with emphysema. (integrisok.com)
Pathology2
Progression2
Severity2
  • To identify whether the extent of arterial stiffness is associated with emphysema severity. (nih.gov)
  • We identified 127 genes whose expression levels were significantly associated with regional emphysema severity while controlling for gene expression differences between individuals. (biomedcentral.com)
Symptoms2
National Emphysema Treatment Trial2
  • Methods: Patient level HRQoL data from RENEW and the National Emphysema Treatment Trial (NETT) were combined and mapped to generic EuroQol 5-dimension health utility questionnaire (EQ-5D) values using a published algorithm. (uzh.ch)
  • How was the National Emphysema Treatment Trial conducted? (nih.gov)
Rehabilitation3
Function1
Upper lobe emphysema1
Combined Pulmonary Fibrosis and Emphysema10
Shortness of Bre11
Cause of emphysema1
Diagnosis of emphysema6
Interstitial Lung Di4
Diffuse2
CPFE7
Obstructive13
Centriacinar Emphysema1
Symptoms of pulmonary emphysema2
Pathophysiology1
Sign of emphysema1
  • With you not having smoked for 20 years, it is quite unlikely that your current dry cough is a sign of emphysema. (medhelp.org)
Subcutaneous emphysema8
Airflow3
Lobe2
  • It usually involves the upper lobe and is the most common type of emphysema. (humpath.com)
  • The newly published findings from the largest study of bilateral lung volume reduction surgery (LVRS) to treat severe emphysema also confirm that patients with upper-lobe emphysema and poor exercise capacity before surgery are more likely to have improved survival compared to similar patients treated with medical therapy without surgery. (psychcentral.com)
Occurs3
Sacs2
Idiopathic3
Development of pulmonary1
  • The aim of this study was to elucidate the roles of MafB in the development of pulmonary emphysema. (ijbs.com)
Mortality2
Cigarette8
Smokers3
Onset1
  • Acute bovine pulmonary emphysema and edema (ABPEE) is one of the more common causes of acute respiratory distress in cattle, particularly adult beef cattle, and is characterized by sudden onset, minimal coughing, and a course that ends fatally or improves dramatically within a few days. (merckvetmanual.com)
Radiographic3
Patients with advanced emphysema1
People with pulmonary1
  • The goal of treatment for people with pulmonary emphysema is to live more comfortably with the disease, control symptoms, and prevent the disease from getting worse, with minimal side effects. (ahealthyme.com)
Prevalence2
  • The prevalence of pulmonary interstitial emphysema widely varies with the population studied. (wikipedia.org)
  • The term 'prevalence' of Berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification usually refers to the estimated population of people who are managing Berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification at any given time. (rightdiagnosis.com)
Pattern of pulmonary2
What is the role of radiography in the diagnosis of emphysema?
What is the role of radiography in the diagnosis of emphysema? (medscape.com)
SPONTANEOUS INTERSTITIAL EMPHYSEMA OF THE LUNGS; REPORT OF AN ADDITIONAL CASE* | Annals of Internal Medicine | American College...
SPONTANEOUS INTERSTITIAL EMPHYSEMA OF THE LUNGS; REPORT OF AN ADDITIONAL CASE* | Annals of Internal Medicine | American College... (annals.org)
Molecular Expressions Microscopy Primer: Specialized Microscopy Techniques - Phase Contrast Photomicrography Gallery -...
Molecular Expressions Microscopy Primer: Specialized Microscopy Techniques - Phase Contrast Photomicrography Gallery -... (micro.magnet.fsu.edu)
Pulmonary Interstitial Emphysema: Pearls, Background, Pathophysiology
Pulmonary Interstitial Emphysema: Pearls, Background, Pathophysiology (emedicine.medscape.com)
Centrilobular emphysema: Diagnosis, treatment, and outlook
Centrilobular emphysema: Diagnosis, treatment, and outlook (medicalnewstoday.com)
CiteSeerX - Pulmonary emphysema Chronic obstructive
CiteSeerX - Pulmonary emphysema Chronic obstructive (citeseerx.ist.psu.edu)
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What is Pleural Effusion? Treatment, Causes & Symptoms (medicinenet.com)
Lung Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Lung Anatomy: Overview, Gross Anatomy, Microscopic Anatomy (emedicine.medscape.com)
Imaging in Pulmonary Interstitial Emphysema: Practice Essentials, Radiography
Imaging in Pulmonary Interstitial Emphysema: Practice Essentials, Radiography (emedicine.medscape.com)
Pulmonary rehab | DailyStrength
Pulmonary rehab | DailyStrength (dailystrength.org)
How much does not smoking improve copd or is it too late? I've smoked for 54 years and have a lobec?
How much does not smoking improve copd or is it too late? I've smoked for 54 years and have a lobec? (drugs.com)
What Is Chronic Obstructive Pulmonary Disease? - ArticleCity.com
What Is Chronic Obstructive Pulmonary Disease? - ArticleCity.com (articlecity.com)
Emphysema - Doctors | Lehigh Valley Health Network
Emphysema - Doctors | Lehigh Valley Health Network (lvhn.org)
What is COPD?
What is COPD? (copdfoundation.org)
Endobronchial Valves Therapy for Advanced Emphysema: A Meta-... : Journal of Bronchology & Interventional Pulmonology
Endobronchial Valves Therapy for Advanced Emphysema: A Meta-... : Journal of Bronchology & Interventional Pulmonology (journals.lww.com)
Emphysema Management and Treatment | Cleveland Clinic
Emphysema Management and Treatment | Cleveland Clinic (my.clevelandclinic.org)
Adoption of Strategies to Mitigate Transmission of COVID-19 During a Statewide Primary Election - Delaware, September 2020 |...
Adoption of Strategies to Mitigate Transmission of COVID-19 During a Statewide Primary Election - Delaware, September 2020 |... (cdc.gov)
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Chronic Obstructive Pulmonary Disease (COPD) and Emphysema in Emergency Medicine: Background, Pathophysiology, Etiology of COPD (emedicine.medscape.com)
Emphysema Diagnosis
Emphysema Diagnosis (news-medical.net)
Mapping: Global Emphysema Market 2018 Reports Indicate | USA | UK | Australia | as the Fastest Growing Region Insight 2018-2023
Mapping: Global Emphysema Market 2018 Reports Indicate | USA | UK | Australia | as the Fastest Growing Region Insight 2018-2023 (medgadget.com)
AVOID SURGERY - Using Your OWN Stem Cells To Accelerate Healing - Join us in Manhattan, KS on December 12th, 2018 from 5:30pm...
AVOID SURGERY - Using Your OWN Stem Cells To Accelerate Healing - Join us in Manhattan, KS on December 12th, 2018 from 5:30pm... (eventbrite.com)
Blood gas test: Procedure and normal values
Blood gas test: Procedure and normal values (medicalnewstoday.com)
Pneumonia - Walking Pneumonia - Treatment | familydoctor.org
Pneumonia - Walking Pneumonia - Treatment | familydoctor.org (familydoctor.org)
Lung problems and volcanic smog: MedlinePlus Medical Encyclopedia
Lung problems and volcanic smog: MedlinePlus Medical Encyclopedia (medlineplus.gov)
Prediction of survival by texture-based automated quantitative assessment of regional disease patterns on CT in idiopathic...
Prediction of survival by texture-based automated quantitative assessment of regional disease patterns on CT in idiopathic... (link.springer.com)
Https://www.medicalnewstoday.com/articles/321044.php
Https://www.medicalnewstoday.com/articles/321044.php (medicalnewstoday.com)
Chronic Obstructive Pulmonary Disease (COPD) | Smoking & Tobacco Use | CDC
Chronic Obstructive Pulmonary Disease (COPD) | Smoking & Tobacco Use | CDC (cdc.gov)