Pulmonary Artery
Hypertension, Pulmonary
Carotid Arteries
Catheterization, Swan-Ganz
Placement of a balloon-tipped catheter into the pulmonary artery through the antecubital, subclavian, and sometimes the femoral vein. It is used to measure pulmonary artery pressure and pulmonary artery wedge pressure which reflects left atrial pressure and left ventricular end-diastolic pressure. The catheter is threaded into the right atrium, the balloon is inflated and the catheter follows the blood flow through the tricuspid valve into the right ventricle and out into the pulmonary artery.
Mesenteric Arteries
Basilar Artery
Pulmonary Wedge Pressure
Coronary Artery Bypass
Vasoconstriction
Iliac Artery
Subclavian Artery
Vertebral Artery
Bronchial Arteries
Radial Artery
Hemodynamics
Mammary Arteries
Carotid Artery, Internal
Endothelium, Vascular
Cardiac Catheterization
Vasodilation
Carotid Artery Diseases
Splenic Artery
Brachial Artery
Lung
Hypertrophy, Right Ventricular
Hepatic Artery
Carotid Artery, Common
The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.
Pulmonary Valve Stenosis
Monocrotaline
A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
Heart Defects, Congenital
Pulmonary Atresia
A congenital heart defect characterized by the narrowing or complete absence of the opening between the RIGHT VENTRICLE and the PULMONARY ARTERY. Lacking a normal PULMONARY VALVE, unoxygenated blood in the right ventricle can not be effectively pumped into the lung for oxygenation. Clinical features include rapid breathing, CYANOSIS, right ventricle atrophy, and abnormal heart sounds (HEART MURMURS).
Heart Septal Defects, Ventricular
Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.
Vascular Neoplasms
Celiac Artery
Arterial Occlusive Diseases
Treatment Outcome
Ophthalmic Artery
Tetralogy of Fallot
A combination of congenital heart defects consisting of four key features including VENTRICULAR SEPTAL DEFECTS; PULMONARY STENOSIS; RIGHT VENTRICULAR HYPERTROPHY; and a dextro-positioned AORTA. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing CYANOSIS.
Mesenteric Artery, Superior
A large vessel supplying the whole length of the small intestine except the superior part of the duodenum. It also supplies the cecum and the ascending part of the colon and about half the transverse part of the colon. It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra.
Tomography, X-Ray Computed
Coronary Vessel Anomalies
Myocytes, Smooth Muscle
Arterio-Arterial Fistula
Aneurysm
Cardiac Output
Constriction, Pathologic
Pulmonary Veins
Umbilical Arteries
Ventricular Function, Right
Middle Cerebral Artery
Dogs
Nitric Oxide
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Renal Artery Obstruction
Thoracic Arteries
Coronary Angiography
Vascular Resistance
Temporal Arteries
Transposition of Great Vessels
A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Ductus Arteriosus, Patent
Popliteal Artery
Ulnar Artery
Catheterization
Echocardiography, Doppler
Echocardiography
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Uterine Artery
Aorta, Thoracic
Carotid Artery, External
Stents
Fontan Procedure
A procedure in which total right atrial or total caval blood flow is channeled directly into the pulmonary artery or into a small right ventricle that serves only as a conduit. The principal congenital malformations for which this operation is useful are TRICUSPID ATRESIA and single ventricle with pulmonary stenosis.
Rats, Sprague-Dawley
Coronary Disease
Sheep
Follow-Up Studies
Thermodilution
Dose-Response Relationship, Drug
Endothelin-1
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
Carotid Artery Injuries
Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)
Cells, Cultured
Rabbits
Ventricular Dysfunction, Right
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
Prospective Studies
Rats, Wistar
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Magnetic Resonance Angiography
Hypoplastic Left Heart Syndrome
Disease Models, Animal
Tricuspid Valve Insufficiency
Acetylcholine
Angioplasty, Balloon
Heart Ventricles
Oxygen
Epoprostenol
Nitric Oxide Synthase
Muscle Contraction
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Axillary Artery
Vascular Malformations
A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.
Postoperative Complications
Truncus Arteriosus, Persistent
A congenital anomaly caused by the failed development of TRUNCUS ARTERIOSUS into separate AORTA and PULMONARY ARTERY. It is characterized by a single arterial trunk that forms the outlet for both HEART VENTRICLES and gives rise to the systemic, pulmonary, and coronary arteries. It is always accompanied by a ventricular septal defect.
Hemoptysis
Ultrasonography, Doppler
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
Nitroprusside
Retinal Artery Occlusion
Nitric Oxide Synthase Type III
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Embolization, Therapeutic
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Persistent Fetal Circulation Syndrome
A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).
Pulmonary Heart Disease
Anastomosis, Surgical
Carotid Artery Thrombosis
Cardiopulmonary Bypass
Heart Bypass, Right
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Arterial Pressure
Enzyme Inhibitors
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Potassium Chloride
Pulmonary Valve Insufficiency
Pulmonary Edema
Cattle
Monitoring, Physiologic
Pulsatile Flow
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Eisenmenger Complex
A condition associated with VENTRICULAR SEPTAL DEFECT and other congenital heart defects that allow the mixing of pulmonary and systemic circulation, increase blood flow into the lung, and subsequent responses to low oxygen in blood. This complex is characterized by progressive PULMONARY HYPERTENSION; HYPERTROPHY of the RIGHT VENTRICLE; CYANOSIS; and ERYTHROCYTOSIS.
Carotid Stenosis
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Aneurysm, False
Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Phenylephrine
Fatal Outcome
Bone Morphogenetic Protein Receptors, Type II
Serotonin
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Heart Murmurs
Heart sounds caused by vibrations resulting from the flow of blood through the heart. Heart murmurs can be examined by HEART AUSCULTATION, and analyzed by their intensity (6 grades), duration, timing (systolic, diastolic, or continuous), location, transmission, and quality (musical, vibratory, blowing, etc).
Risk Factors
Muscle Tonus
Cerebral Angiography
Endarterectomy
NG-Nitroarginine Methyl Ester
Iloprost
An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
Endothelial Cells
Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.
Blood Vessel Prosthesis Implantation
Cyclic GMP
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Myocardial Infarction
Stroke Volume
Receptors, Endothelin
Dilatation, Pathologic
Exercise Test
Aortography
Maxillary Artery
Severity of Illness Index
Nitroglycerin
Blood Vessel Prosthesis
rho-Associated Kinases
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.
Blood Flow Velocity
Aneurysm, Ruptured
Carotid Artery, Internal, Dissection
Vasomotor System
Ultrasonography, Doppler, Color
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Catheterization, Peripheral
Models, Cardiovascular
Myography
Coronary Artery Bypass, Off-Pump
Echocardiography, Transesophageal
Internal Mammary-Coronary Artery Anastomosis
Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.
Angiography, Digital Subtraction
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin. (1/5022)
-The increased delivery of serotonin (5-hydroxytryptamine, 5-HT) to the lung aggravates the development of hypoxia-induced pulmonary hypertension in rats, possibly through stimulation of the proliferation of pulmonary artery smooth muscle cells (PA-SMCs). In cultured rat PA-SMCs, 5-HT (10(-8) to 10(-6) mol/L) induced DNA synthesis and potentiated the mitogenic effect of platelet-derived growth factor-BB (10 ng/mL). This effect was dependent on the 5-HT transporter (5-HTT), since it was prevented by the 5-HTT inhibitors fluoxetine (10(-6) mol/L) and paroxetine (10(-7) mol/L), but it was unaltered by ketanserin (10(-6) mol/L), a 5-HT2A receptor antagonist. In PA-SMCs exposed to hypoxia, the levels of 5-HTT mRNA (measured by competitive reverse transcriptase-polymerase chain reaction) increased by 240% within 2 hours, followed by a 3-fold increase in the uptake of [3H]5-HT at 24 hours. Cotransfection of the cells with a construct of human 5-HTT promoter-luciferase gene reporter and of pCMV-beta-galactosidase gene allowed the demonstration that exposure of cells to hypoxia produced a 5.5-fold increase in luciferase activity, with no change in beta-galactosidase activity. The increased expression of 5-HTT in hypoxic cells was associated with a greater mitogenic response to 5-HT (10(-8) to 10(-6) mol/L) in the absence as well as in the presence of platelet-derived growth factor-BB. 5-HTT expression assessed by quantitative reverse transcriptase-polymerase chain reaction and in situ hybridization in the lungs was found to predominate in the media of pulmonary artery, in which a marked increase was noted in rats that had been exposed to hypoxia for 15 days. These data show that in vitro and in vivo exposure to hypoxia induces, via a transcriptional mechanism, 5-HTT expression in PA-SMCs, and that this effect contributes to the stimulatory action of 5-HT on PA-SMC proliferation. In vivo expression of 5-HTT by PA-SMC may play a key role in serotonin-mediated pulmonary vascular remodeling. (+info)Relaxation of endothelin-1-induced pulmonary arterial constriction by niflumic acid and NPPB: mechanism(s) independent of chloride channel block. (2/5022)
We investigated the effects of the Cl- channel blockers niflumic acid, 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) and 4, 4'-diisothiocyanatostilbene-2,2'-disulphonic acid (DIDS) on endothelin-1 (ET-1)-induced constriction of rat small pulmonary arteries (diameter 100-400 microm) in vitro, following endothelium removal. ET-1 (30 nM) induced a sustained constriction of rat pulmonary arteries in physiological salt solution. Arteries preconstricted with ET-1 were relaxed by niflumic acid (IC50: 35.8 microM) and NPPB (IC50: 21.1 microM) in a reversible and concentration-dependent manner. However, at concentrations known to block Ca++-activated Cl- channels, DIDS (+info)Transcriptional down-regulation of the rabbit pulmonary artery endothelin B receptor during phenotypic modulation. (3/5022)
1. We confirmed that endothelium-independent contraction of the rabbit pulmonary artery (RPA) is mediated through both an endothelin A (ET(A)R) and endothelin B (ET(B2)R) receptor. 2. The response of endothelium-denuded RPA rings to endothelin-1 (ET-1, pD2 = 7.84 +/- 0.03) was only partially inhibited by BQ123 (10 microM), an ET(A)R antagonist. 3. Pretreatment with 1 nM sarafotoxin S6c (S6c), an ET(B)R agonist, desensitized the ET(B2)R and significantly attenuated the response to ET-3 (pD2 = 7.40 +/- 0.02 before, <6.50 after S6c). 4. Pretreatment with S6c had little effect on the response to ET-1, but BQ123 (10 microM) caused a parallel shift to the right of the residual ETAR-mediated response to ET-1 (pD2 = 7.84 +/- 0.03 before S6c, 7.93 +/- 0.03 after S6c, 6.81 +/- 0.05 after BQ123). 5. Binding of radiolabelled ET-1 to early passage cultures of RPA vascular smooth muscle cells (VSMC) displayed two patterns of competitive displacement characteristic of the ET(A)R (BQ123 pIC50 = 8.73 +/- 0.05) or ET(B2)R (S6c pIC50 = 10.15). 6. Competitive displacement experiments using membranes from late passage VSMC confirmed only the presence of the ET(A)R (ET-1 pIC50 = 9.3, BQ123 pIC50 = 8.0, S6c pIC50 < 6.0). 7. The ET(A)R was functionally active and coupled to rises in intracellular calcium which exhibited prolonged homologous desensitization. 8. Using a reverse transcriptase polymerase chain reaction for the rabbit ET(B2)R, we demonstrated the absence of mRNA expression in phenotypically modified VSMC. 9. We conclude that the ET(B2)R expressed by VSMC which mediates contraction of RPA is rapidly down-regulated at the transcriptional level during phenotypic modulation in vitro. (+info)Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene transcription. (4/5022)
We tested the hypothesis that activation of protein kinase C (PKC) and generation of oxidants are critical sequential signals mediating tumor necrosis factor (TNF)-alpha-induced activation of nuclear factor-kappaB (NF-kappaB) and transcription of the intercellular adhesion molecule (ICAM)-1 gene. Stimulation of human pulmonary artery endothelial (HPAE) cells with TNF-alpha (100 U/ml) induced the activation of PKC and, subsequently, generation of oxidants. Pretreatment with calphostin C, a specific PKC inhibitor, prevented oxidant generation after TNF-alpha stimulation, indicating that PKC activation mediated the production of oxidants in HPAE cells. In contrast, pretreatment of HPAE cells with N-acetylcysteine, an antioxidant and a precursor of glutathione, failed to prevent PKC activation, indicating that PKC activation was not secondary to the oxidant production. These findings suggest that oxidant generation in endothelial cells occurs downstream of PKC activation. However, both PKC activation and oxidant generation were necessary for ICAM-1 mRNA expression because the pretreatment of HPAE cells with either calphostin C or N-acetylcysteine inhibited the TNF-alpha-induced activation of NF-kappaB and prevented the activation of ICAM-1 promoter. Prolonged exposure of HPAE cells to the phorbol ester, phorbol-12-myristate-13-acetate, which is known to deplete all except atypical PKC isozymes, failed to prevent TNF-alpha-induced ICAM-1 mRNA expression. We conclude that TNF-alpha-induced oxidant generation secondary to the activation of a phorbol ester-insensitive PKC isozyme signals the activation NF-kappaB and ICAM-1 gene transcription. (+info)Anomalous origin of the left coronary artery from the pulmonary artery: natural history and normal pregnancies. (5/5022)
Two female patients are described with anomalous origin of the left coronary artery arising from the pulmonary artery who sustained an anterolateral myocardial infarction in infancy. Neither patient received surgical treatment although both have lived to middle age with minimal cardiovascular problems and have had uncomplicated pregnancies. Good exercise tolerance and long term survival may be possible even without surgery for patients with this anomaly. (+info)Lactate kinetics at rest and during exercise in lambs with aortopulmonary shunts. (6/5022)
In a previous study [G. C. M. Beaufort-Krol, J. Takens, M. C. Molenkamp, G. B. Smid, J. J. Meuzelaar, W. G. Zijlstra, and J. R. G. Kuipers. Am. J. Physiol. 275 (Heart Circ. Physiol. 44): H1503-H1512, 1998], a lower systemic O2 supply was found in lambs with aortopulmonary left-to-right shunts. To determine whether the lower systemic O2 supply results in increased anaerobic metabolism, we used [1-13C]lactate to investigate lactate kinetics in eight 7-wk-old lambs with shunts and eight control lambs, at rest and during moderate exercise [treadmill; 50% of peak O2 consumption (VO2)]. The mean left-to-right shunt fraction in the shunt lambs was 55 +/- 3% of pulmonary blood flow. Arterial lactate concentrations and the rate of appearance (Ra) and disappearance (Rd) of lactate were similar in shunt and control lambs, both at rest (lactate: 1, 201 +/- 76 vs. 1,214 +/- 151 micromol/l; Ra = Rd: 12.97 +/- 1.71 vs. 12.55 +/- 1.25 micromol. min-1. kg-1) and during a similar relative workload. We found a positive correlation between Ra and systemic blood flow, O2 supply, and VO2 in both groups of lambs. In conclusion, shunt lambs have similar lactate kinetics as do control lambs, both at rest and during moderate exercise at a similar fraction of their peak VO2, despite a lower systemic O2 supply. (+info)Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells. (7/5022)
1. We have studied the modulation of volume-regulated anion channels (VRACs) by the small GTPase Rho and by one of its targets, Rho kinase, in calf pulmonary artery endothelial (CPAE) cells. 2. RT-PCR and immunoblot analysis showed that both RhoA and Rho kinase are expressed in CPAE cells. 3. ICl,swell, the chloride current through VRACs, was activated by challenging CPAE cells with a 25 % hypotonic extracellular solution (HTS) or by intracellular perfusion with a pipette solution containing 100 microM GTPgammaS. 4. Pretreatment of CPAE cells with the Clostridium C2IN-C3 fusion toxin, which inactivates Rho by ADP ribosylation, significantly impaired the activation of ICl,swell in response to the HTS. The current density at +100 mV was 49 +/- 13 pA pF-1 (n = 17) in pretreated cells compared with 172 +/- 17 pA pF-1 (n = 21) in control cells. 5. The volume-independent activation of ICl,swell by intracellular perfusion with GTPgammaS was also impaired in C2IN-C3-pretreated cells (31 +/- 7 pA pF-1, n = 11) compared with non-treated cells (132 +/- 21 pA pF-1, n = 15). 6. Activation of ICl,swell was pertussis toxin (PTX) insensitive. 7. Y-27632, a blocker of Rho kinase, inhibited ICl,swell and delayed its activation. 8. Inhibition of Rho and of Rho kinase by the above-described treatments did not affect the extent of cell swelling in response to HTS. 9. These experiments provide strong evidence that the Rho-Rho kinase pathway is involved in the VRAC activation cascade. (+info)Release of Ca2+ from the sarcoplasmic reticulum increases mitochondrial [Ca2+] in rat pulmonary artery smooth muscle cells. (8/5022)
1. The Ca2+-sensitive fluorescent indicator rhod-2 was used to measure mitochondrial [Ca2+] ([Ca2+]m) in single smooth muscle cells from the rat pulmonary artery, while simultaneously monitoring cytosolic [Ca2+] ([Ca2+]i) with fura-2. 2. Application of caffeine produced an increase in [Ca2+]i and also increased [Ca2+]m. The increase in [Ca2+]m occurred after the increase in [Ca2+]i, and remained elevated for a considerable time after [Ca2+]i had returned to resting values. 3. The protonophore carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone (FCCP), which causes the mitochondrial membrane potential to collapse, markedly attenuated the increase in [Ca2+]m following caffeine application and also increased the half-time for recovery of [Ca2+]i to resting values. 4. Activation of purinoceptors with ATP also produced increases in both [Ca2+]i and [Ca2+]m in these smooth muscle cells. In some cells, oscillations in [Ca2+]i were observed during ATP application, which produced corresponding oscillations in [Ca2+]m and membrane currents. 5. This study provides direct evidence that Ca2+ release from the sarcoplasmic reticulum, either through ryanodine or inositol 1,4, 5-trisphosphate (InsP3) receptors, increases both cytosolic and mitochondrial [Ca2+] in smooth muscle cells. These results have potential implications both for the role of mitochondria in Ca2+ regulation in smooth muscle, and for understanding how cellular metabolism is regulated. (+info)
Two-dimensional echocardiographic measurement of right pulmonary artery diameter in infants and children | JACC: Journal of the...
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Induced cytoskeletal changes in bovine pulmonary artery endothelial cells by resveratrol and the accompanying modified...
Cyclic stretch induces inducible nitric oxide synthase and soluble guanylate cyclase in pulmonary artery smooth muscle cells<...
Role of nitric oxide in regulating neonatal porcine pulmonary artery smooth muscle cell proliferation
Effects of HIV Infection on Pulmonary Artery Pressure in Children
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comparison of the pharmacological and mechanical properties in vitro of large and small pulmonary arteries of the rat |...
Perinatal hypoxia enhances cyclic adenosine monophosphate-mediated BKCa channel activation in adult murine pulmonary artery. -...
Role of Lipoxygenase Metabolites of Arachidonic Acid in Enhanced Pulmonary Artery Contractions of Female Rabbits | Hypertension
Stretch Reflexes from the Main Pulmonary Artery to the Systemic Circulation | Circulation Research
Pulmonary Artery Endothelial Cells | ax3807 (500,000 cells) | Axol Bioscience
Unilateral pulmonary artery thromboembolic occlusion in patients: Is distal arteriopathy a consequence?<...
arteries chart - Graph Diagram
Lung Overexpression of Angiostatin Aggravates Pulmonary Hypertension in Chronically Hypoxic Mice - Inserm
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Plus it
Unilateral Pulmonary Artery Absence or Hypoplasia | Circulation
Volume 5.03 | Jan 27 - Endothelial Cell News
Primary Pulmonary Artery Smooth Muscle Cells; Normal, Human (PASMC) AT
Ambulatory pulmonary artery pressure monitoring during sleep and exercise in normal individuals and patients with COPD | Thorax
Silencing of STIM1 attenuates hypoxia-induced PASMCs proliferation via inhibition of the SOC/Ca2+/NFAT pathway | Respiratory...
Tyrosine phosphorylation of Kv1.5 is upregulated in intrauterine growth retardation rats with exaggerated pulmonary...
Isoflavones
C57BL/6 Mouse Pulmonary Artery Smooth Muscle Cells | Creative Bioarray
Figures and Graphics: Basal and stimulated release of long-acting EDRF by bovine pulmonary arteries
Primary Pulmonary Artery Endothelial Cells; Normal, Human (HPAEC) ATCC
Peripheral pulmonary artery stenosis. | Archives of Disease in Childhood
Browsing Research Articles (Cardiothoracic Surgery) by Title Aneurysm of a peripheral pulmonary artery : case report and brief...
Channelpedia
Identification of Functional Progenitor Cells in the Pulmonary Vasculature
Breathlessness in an ex-miner: an unusual consideration | Thorax
Multiple peripheral pulmonary artery stenoses in adults: a rare cause of severe pulmonary hypertension necessitating lung...
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Original Research: Role of phosphodiesterases in modulation of BK <sub>Ca</sub> ...
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Abstract 415: Sepiapterin Improves the Angiogenesis in Pulmonary Artery Endothelial Cells from Developing Lungs with In Utero...
Atrially based pericardial tunnel for central pulmonary artery construction.
Summary: Basal and stimulated release of long-acting EDRF by bovine pulmonary arteries
Mevastatin Can Cause G1 Arrest and Induce Apoptosis in Pulmonary Artery Smooth Muscle Cells Through a p27Kip1-Independent...
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CHRONIC MASSIVE PULMONARY ARTERY THROMBOSIS* | Annals of Internal Medicine | American College of Physicians
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Pulmonary vascular effects of prostaglandin D<sub>2</sub>, but not its systemic vascular or airway effects, are mediated...
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Effects of hypercapnia and hypocapnia on [Ca<sup>2+</sup>]<sub>i</sub> mobilization in human pulmonary artery...
Clinical determinants of elevated systolic pulmonary artery pressure measured by transthoracic Doppler echocardiography in...
Surgical Reconstruction with Autologous Tissue in a Case of Isolated Unilateral Absence of the Right Pulmonary Artery
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Multimodal imaging of anomalous left coronary artery from the pulmonary artery in a 75-year-old woman - Fingerprint - Mayo...
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Pathobiology of pulmonary arterial hypertension.
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Anomalous origin of left coronary artery from pulmonary artery (ALCAPA): a case series and review of literature - Journal of ...
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Adding another dimension to a cell culture model for pulmonary arterial hypertension - BIOENGINEER.ORG
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Complex phosphatase regulation of Ca2+-activated Cl- currents in pulmonary arterial smooth muscle cells. - Nuffield Department...
AID 211903 - In vitro binding affinity towards Tachykinin receptor 2 using rabbit pulmonary artery tissues - PubChem
Pulmonary arterial hypertension (PAH) is a multifactorial cardiopulmonary disease characterized by an elevation of pulmonary...
Contractile and electrophysiological properties of pulmonary artery smooth muscle are not altered in TASK-1 knockout mice. -...
Pulmonary artery
Pulmonary circuit Transverse section of thorax, showing relations of pulmonary artery. Pulmonary artery Pulmonary artery.Deep ... The largest pulmonary artery is the main pulmonary artery or pulmonary trunk from the heart, and the smallest ones are the ... The pulmonary trunk splits into the right and the left main pulmonary artery. The left main pulmonary artery is shorter than ... These in turn branch into subsegmental pulmonary arteries. These eventually form intralobular arteries. The pulmonary arteries ...
Pulmonary artery catheter
... pulmonary artery, and the filling pressure (pulmonary wedge pressure) of the left atrium. The pulmonary artery catheter is ... is a balloon-tipped catheter that is inserted into a pulmonary artery in a procedure known as pulmonary artery catheterization ... The standard pulmonary artery catheter has two lumens (Swan-Ganz) and is equipped with an inflatable balloon at the tip, which ... "Pulmonary Artery Catheterization: Background, Settings in Which Use of a PAC Is Appropriate, Settings in Which Use of a PAC Is ...
Pulmonary artery banding
... narrowing the diameter of the pulmonary artery to reduce blood flow to the lungs and reduce pulmonary artery pressure. PAB ... The goal of PAB is to reduce pulmonary artery pressure and excess pulmonary blood flow. PAB involves the insertion of a band ... as minimal changes to the diameter of the pulmonary artery can have drastic effects on resistance and blood flow. The pulmonary ... "Mortality of Pulmonary Artery Banding in the Current Era: Recent Mortality of PA Banding." The Annals of Thoracic Surgery 74.4 ...
Pulmonary artery sling
In pulmonary artery sling, the left pulmonary artery anomalously originates from a normally positioned right pulmonary artery. ... Pulmonary artery sling is a rare condition in which the blood vessels between the heart and the lungs have formed incorrectly ... The left pulmonary artery arises anterior to the right main bronchus near its origin from the trachea, courses between the ... The first known case of pulmonary artery sling was diagnosed and surgically repaired by Willis J. Potts at Lurie Children's ...
Stenosis of pulmonary artery
Stenosis of the pulmonary artery is a condition where the pulmonary artery is subject to an abnormal constriction (or stenosis ... Both stenosis of the pulmonary artery and pulmonary valve stenosis are causes of pulmonic stenosis.[citation needed]In some ... For peripheral pulmonary artery stenosis in Alagille syndrome". Tex Heart Inst J. 25 (1): 79-82. PMC 325508. PMID 9566070. v t ... "Pulmonary Artery Stenosis". Retrieved 2009-01-18. Saidi AS, Kovalchin JP, Fisher DJ, Ferry GD, Grifka RG (1998). "Balloon ...
Anomalous left coronary artery from the pulmonary artery
... (ALCAPA, Bland-White-Garland syndrome or White-Garland syndrome) is a ... The anomalous left coronary artery (LCA) usually arises from the pulmonary artery instead of the aortic sinus. In fetal life, ... "Long-Term Outcome of the Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery (ALCAPA) in Children After ... "Anomalous origin of the left coronary artery from the pulmonary artery: collective review of surgical therapy". The Annals of ...
Preload (cardiology)
"Pulmonary Artery Wedge Pressure • LITFL • CCC Equipment". Life in the Fast Lane • LITFL • Medical Blog. 2019-01-04. Retrieved ... Pulmonary wedge pressure will overestimate left ventricle pressure in people with mitral valve stenosis, pulmonary hypertension ... "CV Physiology , Pulmonary Capillary Wedge Pressure". www.cvphysiology.com. Retrieved 2019-10-06. "Pulmonary: Heart Failure". ... When both the heart and lungs are healthy, pulmonary wedge pressure is equal to left ventricle diastolic pressure and can be ...
Cardiac output
... knowledge of the pulmonary artery catheter. Pulmonary Artery Catheter Study Group". JAMA. 264 (22): 2928-32. doi:10.1001/jama. ... The pulmonary artery catheter (PAC) introduced to clinical practice in 1970, also known as the Swan-Ganz catheter, provides ... The average velocity in a vessel, i.e., the aorta or the pulmonary artery, is quantified by measuring the average signal ... Phillips RA, Hood SG, Jacobson BM, West MJ, Wan L, May CN (2012). "Pulmonary Artery Catheter (PAC) Accuracy and Efficacy ...
Behçet's disease
Nodules, consolidations, cavities and ground glass lesions are common in patients with pulmonary involvement. Pulmonary artery ... and in severe cases can be life-threatening if the outlet pulmonary artery develops an aneurysm which ruptures causing severe ... ElGuindy MS, ElGuindy AM (October 2017). "Aneurysmal coronary artery disease: An overview". Global Cardiology Science and ... Although infrequent, myocardial infarction (heart attack) with angiographically identified acute coronary artery thrombosis has ...
Acute liver failure
Pulmonary artery catheterization should be considered. Hypotension should be treated preferentially with fluids, but systemic ... Pulmonary edema and pulmonary infections are commonly seen in patients with ALF. Mechanical ventilation may be required. ... Pulmonary complications occur in up to 50% of patients. Severe lung injury and hypoxemia result in high mortality. Most cases ... Pulmonary haemorrhage, pleural effusions, atelectasis, and intrapulmonary shunts also contribute to respiratory difficulty. In ...
Raja M. Flores
Flores, RM (Feb 2011). "Reply to difference in outcome in the transection of the pulmonary artery and vein". The Journal of ... Garcia, A; Byrne, JG; Bueno, R; Flores, RM (Dec 2008). "Aneurysm of the main pulmonary artery". Annals of Thoracic and ...
Lung allocation score
... systolic pressure of the pulmonary artery; mean pressure of the pulmonary artery (only required of sarcoidosis patients); ... cystic fibrosis Pulmonary Fibrosis, etc.); age of the patient; body mass index; presence or absence of diabetes mellitus; ... pulmonary capillary wedge pressure (PCW pressure); flow rate of supplemental oxygen required at rest; distance walked in six ... article on page 7 of the Winter 2007 Pathlight newsletter of the Pulmonary Hypertension Association. Grady, Denise: "Updated ...
Patent ductus arteriosus
The pulmonary artery is not seen. An echocardiogram of a coiled PDA: One can see the aortic arch, the pulmonary artery, and the ... to the pulmonary artery. Symptoms are uncommon at birth and shortly thereafter, but later in the first year of life there is ... resulting in an abnormal transmission of blood from the aorta to the pulmonary artery. PDA is common in newborns with ... usually from aorta to pulmonary artery, with higher flow during systole and lower flow during diastole) cardiomegaly (enlarged ...
Pulmonary thromboendarterectomy
Specifically, endartectomy is associated with reperfusion pulmonary edema and "pulmonary artery steal". Reperfusion pulmonary ... Pulmonary artery steal occurs in 70% of patients. It is related to changes in blood flow over areas of pulmonary vasculature ... Reperfusion pulmonary edema after pulmonary artery thromboendarterectomy. Levinson RM, Shure D, Moser KM. Am Rev Respir Dis. ... from the pulmonary arteries, which supply blood to the lungs.[citation needed] Surgery is indicated in patients with pulmonary ...
Pulmonary vein
Behind the pulmonary artery is the bronchus. The right main pulmonary veins (contains oxygenated blood) pass behind the right ... At the root of the lung, the right superior pulmonary vein lies in front of and a little below the pulmonary artery; the ... Bronchial anatomy Transverse section of thorax, showing relations of pulmonary artery. Pulmonary vessels, seen in a dorsal view ... The pulmonary veins are part of the pulmonary circulation. There are four main pulmonary veins, two from each lung - an ...
Rasmussen's aneurysm
Pulmonary artery aneurysms are rare. Historically, pulmonary artery aneurysms were believed to be a common cause of hemoptysis ... the actual bronchial bleeding may be from the bronchial artery, rather than from the pulmonary artery.[medical citation needed ... Rasmussen's aneurysm is a pulmonary artery aneurysm associated with a cavitary lung lesion. It was originally described by ... "Aneurysms of the Pulmonary Arteries". Chest. 94 (5): 1065-1075. doi:10.1378/chest.94.5.1065. PMID 3053058. v t e (All articles ...
Right ventricular hypertrophy
Therefore, the main causes of RVH are pathologies of systems related to the right ventricle such as the pulmonary artery, the ... PH leads to increased pulmonary artery pressure. The right ventricle tries to compensate for this increased pressure by ... Treatment of pulmonary hypertension will depend on the specific cause of the pulmonary hypertension. On top of this, the ... Common causes of PH include chronic obstructive pulmonary disease (COPD), pulmonary embolism, and other restrictive lung ...
Willis J. Potts
The surgery involved making a tiny incision in the aorta and a tiny incision in the pulmonary artery and then sewing the two ... In 1953, Potts was the first surgeon to successfully repair a pulmonary artery sling, an abnormality in which the lung blood ... In addition, Potts performed the first successful repair of a cardiovascular abnormality known as a pulmonary artery sling. He ... to the nearby pulmonary artery (which sends blood to the lungs). In 1946, Potts and Smith devised an operation for blue baby ...
Fetal circulation
This blood is pumped into the pulmonary artery. At the pulmonary artery, it is met with high pulmonary vascular resistance as a ... Lastly, due to the decreased pulmonary vascular resistance, the pressure of the pulmonary artery will fall until it is lower ... Because the aorta has lower pressure than the pulmonary artery, most of the blood flows across the ductus arteriosus away from ... As the oxygen-rich blood from the aorta flows across the ductus arteriosus to the pulmonary artery, the ductus arteriosus will ...
Ascending aorta
... common to it and the pulmonary artery. The ascending aorta is covered at its commencement by the trunk of the pulmonary artery ... with the pulmonary artery. The only branches of the ascending aorta are the two coronary arteries which supply the heart; they ... it rests upon the left atrium and right pulmonary artery. On the right side, it is in relation with the superior vena cava and ...
Anesthetic technician
Swan-Ganz pulmonary artery catheter insertion and monitoring. Intra-operative blood salvage setup, operating and monitoring. ...
Carlos Echandi
The bullet perforated his pulmonary artery, killing him. Both doctors' funerals were held the next day in the Metropolitan ...
GATA2 deficiency
... pulmonary artery hypertension; pulmonary ventilation and diffusion defects as defined by pulmonary function testing that may ... The regimen also improves or normalizes lung function in cases of pulmonary alveolar proteinosis and pulmonary artery ... Lung: Pulmonary alveolar proteinosis (unlike most other cases of pulmonary alveolar proteinosis, the GATA2 deficiency-induced ... Other presentations and/or developments (see Signs and symptoms) include: 1) pulmonary alveolar proteinosis; 2) tumors caused ...
Hughes-Stovin syndrome
The syndrome is also identified as being "characterized by pulmonary/bronchial artery aneurysms and thrombophlebitis, without ... Hughes, JP; Stovin, PG (January 1959). "Segmental pulmonary artery aneurysms with peripheral venous thrombosis". British ... the diagnostic and therapeutic challenges of peripheral pulmonary artery aneurysms". QJM: An International Journal of Medicine ... Multiple pulmonary aneurysms Peripheral venous thrombosis Recurrent fever Chills Hemoptysis Cough There is no rigid set of ...
Hemoptysis
Hughes, JP; Stovin, PG (January 1959). "Segmental pulmonary artery aneurysms with peripheral venous thrombosis". British ... Angiography of bronchial arteries can be performed to locate the bleeding, and it can often be embolized. Bronchial artery ... Acute pulmonary edema". N. Engl. J. Med. 353 (26): 2788-96. doi:10.1056/NEJMcp052699. PMID 16382065. "Endometriosis". The ... November 2013). "Bronchial artery embolization to control hemoptysis: comparison of N-butyl-2-cyanoacrylate and polyvinyl ...
History of medicine
... the pulmonary artery takes it to the lungs. Later, the pulmonary vein then mixes air from the lungs with blood to form arterial ... Blood enhanced with pneuma, which means wind or breath, is carried by the arteries. The path that blood take is as follows: ... He also distinguished between veins and arteries, noting that the latter pulse and the former do not. Thus, while working at ... Michael Servetus (1511-1553). Known as the first European to correctly describe pulmonary circulation. Andreas Vesalius (1514- ...
Pericardium
Surrounds heart and bases of pulmonary artery and aorta. Deep to sternum and anterior chest wall. The right phrenic nerve ... Another feature is the sharp delineation of pulmonary artery and transverse aorta due to lung deposition between these two ... Pericardial arteries supply blood to the dorsal portion of the pericardium. The pericardium sets the heart in mediastinum and ... This junction occurs at two areas: the ventricular outflow tracts where the aorta and pulmonary trunk leave the heart, and the ...
Fikri Alican
"Left Lung Replantation with Immediate Right Pulmonary Artery Ligation". Annals of Surgery. 174 (1): 34-43. doi:10.1097/00000658 ...
Thoracic duct
Transverse section of thorax, showing relations of pulmonary artery. The arch of the aorta, and its branches. Deep lymph nodes ... The duct extends vertically in the chest and curves posteriorly to the left carotid artery and left internal jugular vein. At ...
List of dog diseases
Pulmonary hypertension* is high pressure in the pulmonary artery. In dogs it can be caused by heartworm disease, pulmonary ... Heartworms live in the pulmonary artery and right ventricle of the heart. Heartworm disease in dogs is spread by mosquitoes ... Most commonly the narrowing occurs at the pulmonary valve but it can also occur below the valve (subvalvular) or above the ... However, a large defect can result in heart failure or in pulmonary hypertension leading to a right-to-left shunt. Atrial ...
List of ICD-9 codes 390-459: diseases of the circulatory system
417.0 Arteriovenous fistula of pulmonary vessels 417.1 Aneurysm of pulmonary artery 417.8 Other specified diseases of pulmonary ... 415 Acute pulmonary heart disease 415.0 Acute cor pulmonale 415.1 Pulmonary embolism and infarction 415.11 Iatrogenic pulmonary ... of iliac artery 443.23 Dissection of renal artery 443.24 Dissection of vertebral artery 443.29 Dissection of other artery 443.8 ... pulmonary embolism 415.19 Other pulmonary embolism and infarction 416 Chronic pulmonary heart disease 416.0 Primary pulmonary ...
Pulmonary agenesis
Pulmonary angiography assists in detecting the presence of pulmonary artery branches, differentiating pulmonary agenesis to ... Verwey, Charl; Van der Merwe, Cornelis; Pillay, Tanyia (April 28, 2017). "Pulmonary agenesis, pulmonary aplasia and pulmonary ... pulmonary agenesis and aplasia differ from pulmonary hypoplasia in their underlying cause. Unlike pulmonary hypoplasia which in ... The difference between pulmonary agenesis and aplasia is that pulmonary agenesis has complete absence of lung tissue, airways, ...
NOX4
2005). "Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells". Arterioscler. ... 2005). "Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins". ...
List of signs and symptoms of diving disorders
Pulmonary DCS is very rare in divers. The table below classifies the effects by affected organ and bubble location. If the ... The results may range from pain in the joints where the bubbles form to blockage of an artery leading to damage to the nervous ... Neuman, Tom S (2003). "10.5: Arterial Gas Embolism and Pulmonary Barotrauma". In Brubakk, Alf O; Neuman, Tom S (eds.). Bennett ... Neuman, Tom S (2003). "10.5: Arterial Gas Embolism and Pulmonary Barotrauma". In Brubakk, Alf O; Neuman, Tom S (eds.). Bennett ...
Atretochoana
... and an absence of pulmonary arteries. Its skin is filled with capillaries that penetrate the epidermis, allowing gas exchange. ...
Magdi Yacoub
He carried out a number of Ross procedures, where the diseased aortic valve is replaced with the person's own pulmonary valve, ... in older people with transposition of the great arteries with an intact ventricular septum (IVS). Yacoub began the transplant ... With A. C. Yankah and R. Hetzer "Vagotomy through mediastinoscopy for pulmonary osteoarthropathy. British Journal of Diseases ... Torres, Enrique Garcia (11 July 2012). "Ross Procedure With Pulmonary Autograft Reinforcement". CTSNet. Mark Ruzmetov, Karl F. ...
List of diseases (C)
... synostosis syndactyly jejunal atresia Coronaro-cardiac fistula Coronary arteries congenital malformation Coronary artery ... Congenital v Congenital toxoplasmosis Congenital unilateral pulmonary hypoplasia Congenital vagal hyperreflexivity Congenital ... Carnitine-acylcarnitine translocase deficiency Carnosinase deficiency Carnosinemia Caroli disease Carotenemia Carotid artery ... leukemia Chronic myelomonocytic leukemia Chronic necrotizing vasculitis Chronic neutropenia Chronic obstructive pulmonary ...
Bronchopulmonary segment
These arteries branch from the pulmonary and bronchial arteries, and run together through the center of the segment. Veins and ... "Naming the bronchopulmonary segments and the development of pulmonary surgery". Ann Thorac Surg. 55 (1): 184-8. doi:10.1016/ ...
Local blood flow regulation
Pulmonary (lung) circulation undergoes hypoxic vasoconstriction, which is a unique mechanism of local regulation in that the ... the splanchnic artery. Skeletal muscle is influenced by multiple factors. First, metabolites that are produced by active muscle ... "Pulmonary Blood Flow Regulation". www.pathwaymedicine.org. Retrieved 2019-12-18. "CV Physiology , Active Hyperemia". www. ...
List of circulatory system conditions
Total anomalous pulmonary venous connection Hypoplastic left heart syndrome (HLHS) Transposition of the great arteries (d-TGA) ... Truncus arteriosus (Persistent) Tricuspid atresia Interrupted aortic arch Coarctation of aorta Pulmonary atresia (PA) Pulmonary ... valve stenosis Pulmonary valve stenosis Mitral insufficiency/regurgitation Tricuspid insufficiency/regurgitation Pulmonary ... Acyanotic heart defect Atrial septal defect Cor triatriatum Dextro-Transposition of the great arteries Double aortic arch ...
Percutaneous pulmonary valve implantation
... pulmonary artery occlusion, pulmonary artery rupture, or coronary artery compression impeding blood flow. Death is rare, and is ... October 2000). "Percutaneous replacement of pulmonary valve in a right-ventricle to pulmonary-artery prosthetic conduit with ... Percutaneous pulmonary valve implantation (PPVI), also known as transcatheter pulmonary valve replacement (TPVR), is the ... PPVI can be used to repair congenital defects in the pulmonary valve or right ventricular outflow tract dysfunction, such as ...
Effects of cannabis
Remington TL, Fuller J, Chiu I (November 2015). "Chronic necrotizing pulmonary aspergillosis in a patient with diabetes and ... particularly those with some degree of coronary artery or cerebrovascular disease, poses greater risks due to the resulting ...
Fetal aortic stenosis
In the hybrid procedure, bilateral pulmonary artery bands are positioned to limit pulmonary flow while, at the same time, ... The atrial septum is removed, the aortic arch is reconstructed to remove any hypoplasia, and then the main pulmonary artery is ...
Cardiac catheterization
Contrast is injected into the pulmonary trunk, left or right pulmonary artery, or segment of the pulmonary artery.[citation ... This device is implanted into the pulmonary artery to permit real-time measurement of the pulmonary artery pressure over time.[ ... arteries are not used. Values are commonly obtained for the right atrium, right ventricle, pulmonary artery, and pulmonary ... Right ventricular pressure Pulmonary artery pressure Pulmonary capillary wedge pressure Systemic vascular resistance Pulmonary ...
Paul N. Yu
Philadelphia, Lea & Febiger, Volumes 1 - 16, 1972 - 1988 (Yearly). "Pulmonary blood volume in health and disease," by Paul N. ... and key observations about the care of patients with coronary artery disease. He cared for prominent individuals such as the ... Yu performed pioneering research in cardiac physiology, making seminal observations about the pulmonary circulation in health ... co-editor of the 16-volume Progress in Cardiology and author of the textbook Pulmonary Blood Volume in Health and Disease. The ...
Pulmonary atresia with ventricular septal defect
The most severe variant involves the presence of severely hypoplastic main pulmonary arteries and branch pulmonary arteries, ... septal defect involves pulmonary atresia with normally developed main pulmonary artery and branch pulmonary arteries, the blood ... these arteries usually develop but then start deteriorating after pulmonary arteries grow, in fetuses with PAVSD, the pulmonary ... Catheter procedure for pulmonary artery branches Systemic-to-pulmonary artery shunt Neonatal complete repair One-stage complete ...
Double inlet left ventricle
Shunt between superior vena cava and distal right pulmonary artery report of a clinical application. N Engl J Med 259: 117, ... if there is no pulmonary valve stenosis, a pulmonary valve banding is necessary to prevent pulmonary hypertension and the ... The goal of all of these is separating the pulmonary and the systemic circulation. Usually, DILV is associated with other ... There is a big shunt left-right with a quickly evolutive pulmonary hypertension. Without life-prolonging interventions, the ...
Interatrial sulcus
... while anteriorly it is hidden by the pulmonary artery and aorta. This article incorporates text in the public domain from page ...
Thomas Sydenham
A fragment on pulmonary consumption was found among his papers. His collected writings occupy about 600 pages 8vo, in the Latin ... To him is attributed the prescient dictum, "A man is as old as his arteries." Thomas Sydenham was born at Wynford Eagle in ... Weber T, Mayer CC (November 2020). ""Man Is as Old as His Arteries" Taken Literally: In Search of the Best Metric". ... " "A man is as old as his arteries." "The arrival of a good clown exercises a more beneficial influence upon the health of a ...
2007 Rugby World Cup squads
Martín Gaitán was forced to withdraw from the squad on 18 August after it was discovered he had a blocked artery in his heart, ... Squad released 21 July 2007 Pierre Spies was withdrawn from the squad after developing a condition believed to be a pulmonary ...
Ventral slot
During these steps it is important not to break through the lateral border of the disk space, otherwise the vertebral artery ... if the animal does not suffer from pulmonary complications." In terms of today's statistical basis surgeons are not able to ...
Childhood immunizations in the United States
... break in the bone hospital acquired infections blockage of the main artery of the lung or one of its branches by a blood clot ... that has traveled from elsewhere in the body through the bloodstream (pulmonary embolism) pneumonia breathing difficulty that ...
Pulmonary Vascular Research Institute
The heart has to work very hard to pump blood through the narrowed arteries in the lungs and eventually the patient develops ... This condition is called pulmonary hypertension, which leads to pulmonary vascular disease (PVD), the progressive obstruction ... guidelines and consensus articles exclusively in the fields of the pulmonary circulation and pulmonary vascular disease. It is ... The Pulmonary Vascular Research Institute (PVRI) is a UK registered medical research charity. It is registered Charity in the ...
Cardiac magnetic resonance imaging perfusion
To screen patients who have chest pain and risk factors for coronary artery disease, to assess for ischaemia which may be ... including acute pulmonary oedema and cardiac arrest (occurring in ≈1 in 1000 patients).[citation needed] Rieber, J. (2005). " ... It is becoming increasingly established as a marker of prognosis in patients with coronary artery disease. There are two main ... enters more slowly due to a narrowing of the coronary artery supplying it. This is called a perfusion defect and usually ...
Elizabeth Stride
There was no clot in the pulmonary artery, but the right ventricle was full of dark clot. The left was firmly contracted as to ... The arteries and other vessels contained in the sheath were all cut through. The cut through the tissues on the right side was ... From this, it was evident that the haemorrhage was caused through the partial severance of the left carotid artery and a small ... As the blood vessels on only one side of Stride's neck had been cut, with her carotid artery only partially severed, Blackwell ...
Exhaled nitric oxide
In the latter condition, inhaled NO is used as a diagnostic test of the response of the pulmonary arteries to vasodilators ( ... Today, NO is not only used in breath tests but also as a therapeutic agent for conditions such as pulmonary arterial ... Exhaled NO is minimally increased in chronic obstructive pulmonary disease, but levels may rise in sudden worsenings of the ... In 1987, experiments with coronary arteries showed that nitric oxide was the long sought endothelium-derived relaxing factor. ...
Per- and polyfluoroalkyl substances
Exposure to aerosolized PFASs is associated with alveolic edema, polymer fume fever, severe dyspnea, decreased pulmonary ... "Probable Link Evaluation for heart disease (including high blood pressure, high cholesterol, coronary artery disease)" (PDF). ...
Computed tomography angiography
CT pulmonary angiogram (CTPA) is used to examine the pulmonary arteries in the lungs, most commonly to rule out pulmonary ... CTA can be used assess acute stroke patients by identifying clots in the arteries of the brain. It can also be used to identify ... CTA is also used in the assessment of native and transplant renal arteries. While CTA is great for imaging of the kidneys, it ... CTA can be used in the legs to detect atherosclerotic disease that has narrowed the arteries. It can also be used to image ...
Whooping cough
The elevated number of white blood cells leads to pulmonary hypertension, a major cause of death by pertussis. In infants who ... and vertebral artery dissection. Violent coughing can cause the pleura to rupture, leading to a pneumothorax. Vomiting after a ...
Fibrinolysis
They are given following a heart attack to dissolve the thrombus blocking the coronary artery; experimentally after a stroke to ... It is therefore used to indicate deep-vein thrombosis, pulmonary embolism, DIC and efficacy of treatment in acute myocardial ... allow blood flow back to the affected part of the brain; and in the event of pulmonary embolism. Thrombolysis refers to the ...
Pulmonary Artery Sling Differential Diagnoses
... sling is created by anomalous origin of the left pulmonary artery from the posterior aspect of the right pulmonary artery. The ... anomalous left pulmonary artery courses over the right mainstem bronchus and then from right to left, posterior to the trachea ... encoded search term (Pulmonary Artery Sling) and Pulmonary Artery Sling What to Read Next on Medscape ... Pulmonary Artery Sling Differential Diagnoses. Updated: Jun 13, 2017 * Author: Stuart Berger, MD; Chief Editor: Howard S Weber ...
Enlarged Pulmonary Artery Signals Risk for COPD Exacerbation
A ratio of pulmonary artery to aorta diameter that is greater than 1 is significantly and independently associated with risk ... A pulmonary artery:aorta (PA:A) ratio greater than 1 is significantly associated with a risk for future severe exacerbation; ... September 28, 2012 (Vienna, Austria) - The ratio of the diameter of the pulmonary artery to the diameter of the aorta is a ... Cite this: Enlarged Pulmonary Artery Signals Risk for COPD Exacerbation - Medscape - Sep 28, 2012. ...
Pulmonary arteries: MedlinePlus Medical Encyclopedia Image
A case of Behcet disease with pulmonary artery pseudoaneurysm: long term follow-up
Main Pulmonary Artery Band
... our pediatric heart specialists can narrow a main artery as a temporary fix. Learn more at Childrens Health. ... The main pulmonary artery band creates a narrowing of the main pulmonary artery to reduce blood flow to the lungs and decrease ... What are the benefits of Pediatric Main Pulmonary Artery Band?. By reducing extra blood flow to the lungs, the main pulmonary ... Other times a pulmonary artery band is placed in an infant born with a hole in their heart. This gives the infant a chance to ...
Diagnosing Pulmonary Artery Hypertension in a Woman With Systemic Sclerosis
What are the challenges of diagnosing pulmonary arterial hypertension in this patient? ... Diagnosis of Pulmonary Arterial Hypertension in a Patient With Systemic Sclerosis Jörg HW Distler, MD; Marius M Hoeper, MD; ... The 2022 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension With First Author, Marc Humbert ... Cite this: Diagnosis of Pulmonary Arterial Hypertension in a Patient With Systemic Sclerosis - Medscape - Mar 01, 2008. ...
Pulmonary Artery Sling Clinical Presentation: History and Physical Examination
... sling is created by anomalous origin of the left pulmonary artery from the posterior aspect of the right pulmonary artery. The ... anomalous left pulmonary artery courses over the right mainstem bronchus and then from right to left, posterior to the trachea ... encoded search term (Pulmonary Artery Sling) and Pulmonary Artery Sling What to Read Next on Medscape ... Pulmonary Artery Sling Clinical Presentation. Updated: Jun 13, 2017 * Author: Stuart Berger, MD; Chief Editor: Howard S Weber, ...
Pulmonary Artery Reconstruction Program | Children's Healthcare of Atlanta
Our Pulmonary Artery Reconstruction program providing innovative treatment and care for patients with pulmonary artery disease. ... Pulmonary Artery Reconstruction Program. Leading the way in innovative care for patients with pulmonary artery disease ... Co-Director of Pulmonary Artery Reconstruction Program. Watch Dr. Bauser-Heaton explain what makes the Pulmonary Artery ... This program treats patients with the diagnosis of major aortopulmonary collateral arteries (MAPCAs), isolated pulmonary artery ...
A case of Behcet disease with pulmonary artery pseudoaneurysm: long term follow-up
MAUDE Adverse Event Report: MERIT MEDICAL SINGAPORE PTE LTD. CRITICATH¿ PA CATHETER PULMONARY ARTERY CATHETER
Aneurysm of the pulmonary artery in a sheep with pulmonary adenocarcinoma
... there are a few described cases of artery aneurysms or pseudoaneurysms of the pulmonary artery associated with pulmonary ... Figure 2 Pulmonary artery of an adult female "Churra Galega Bragançana" sheep. The wall of the artery is thin (aneurysm) (1.135 ... Aneurysms of the pulmonary artery associated with pulmonary neoplasia have been rarely reported in humans and, to the authors ... The morphologic diagnosis was aneurysm of the pulmonary artery and pulmonary adenocarcinoma, with bronchopneumonia. ...
Unilateral Obliteration of the Pulmonary Artery in Emphysema | Thorax
Anomalous Origin of the Pulmonary Artery Off the Aorta
... pediatric cardiologists and heart surgeons provide top-notch treatment for anomalous origin of the right or left pulmonary ... origin of the pulmonary artery, the left or right coronary arteries branch off the pulmonary artery and carries blood from the ... We offer anomalous origin of the right or left pulmonary artery care at Nemours Childrens Health, Pensacola and our hospital ... We offer care for newborns and children with anomalous origin of the right or left pulmonary artery at Nemours Childrens ...
e0127 Determination of pulmonary artery pressure and cardiac output in rat | Heart
Anomalous right coronary artery arising from the pulmonary artery | Haider Warraich, MD
Anomalous right coronary artery arising from the pulmonary artery. Ann Thorac Surg. 2012;93 :e75. ... Anomalous right coronary artery arising from the pulmonary artery Citation:. Warraich H, Matyal R, Shahul S, Senthilnathan V, ... Mahmood F. Anomalous right coronary artery arising from the pulmonary artery. Ann Thorac Surg. 2012;93 :e75. ...
Posture, Exercise and Pulmonary Artery Pressure in Chronic Obstructive Airways Disease | Clinical Science | Portland Press
Congenital total lipodystrophy and peripheral pulmonary artery stenosis | Archives of Disease in Childhood
In peripheral pulmonary artery stenosis, both are low, analogous to the situation after pulmonary artery banding to reduce ... pulmonary hypertension is used imprecisely. Pulmonary hypertension implies a pulmonary artery pressure higher than normal but ... If the pulmonary artery diastolic pressure is high, the pulmonary component of the second sound is likely to be accentuated. In ... The intensity of the pulmonary component of the second heart sound depends primarily on the pulmonary artery diastolic pressure ...
WHO EMRO | A case of Behçet disease with pulmonary artery pseudoaneurysm: long term follow-up | Volume 16, issue 3 | EMHJ...
... indicating a large pulmonary artery aneurysm Figure 2 Digital subtraction angiography showing a cavity at the pulmonary artery ... pulmonary artery aneurysm), thrombotic occlusion, mainly in the vena cava, pulmonary infarction and pulmonary haemorrhage. ... Pulmonary manifestations in patients are mainly related to vasculitis of the pulmonary arteries, veins and septal capillaries. ... More than 200 cases of BD with pulmonary involvement have been reported in the literature. The pulmonary arteries are the ...
Pulmonary artery dissection (PAD) in a patient with diffuse interstitial lung disease and chronic thromboembolic pulmonary...
Pulmonary artery dissection (PAD) in a patient with diffuse interstitial lung disease and chronic thromboembolic pulmonary ... Pulmonary artery dissection (PAD) in a patient with diffuse interstitial lung disease and chronic thromboembolic pulmonary ... Pulmonary artery dissection (PAD) in a patient with diffuse interstitial lung disease and chronic thromboembolic pulmonary ... Pulmonary artery dissection (PAD) in a patient with diffuse interstitial lung disease and chronic thromboembolic pulmonary ...
Percutaneous retrieval of a jugular catheter fragment from the pulmonary artery of a foal in: Journal of the American...
The effects of severe aortic stenosis and high pulmonary artery pressure on aortic valve replacement
Pulmonary arterial pressure of the patients was measured using echocardiography. Preoperative average pulmonary artery systolic ... Material and Methods: Data from files of 31 patients with systolic pulmonary artery pressure over 50 mm Hg and with pure severe ... We believe that AVR may be performed in severe aortic stenosis cases with high pulmonary pressure with acceptable ortality, ... Pulmonary hypertension development in pure severe aortic stenosis is a situation that affects mortality and morbidity. ...
Peripheral pulmonary artery aneurysm presenting as a solitary pulmonary nodule | Sumários.org
The final diagnosis was a solitary peripheral pulmonary artery saccular aneurysm. The patient was submitted to a pulmonary ... Peripheral pulmonary artery aneurysms that arise from segmental or intrapulmonary branches are extremely rare, and their ... We report the case of a 63-year-old female patient who was evaluated due to a solitary pulmonary nodule. ...
RePub, Erasmus University Repository:
Pulmonary artery size and function after fontan operation at a young age
Endothelial function, Fontan operation, Pulmonary artery size, Shear stress Persistent URL doi.org/10.1002/jmri.21544, hdl. ... Pulmonary artery size and function after fontan operation at a young age. Publication. Publication. Journal of Magnetic ... Purpose: To assess pulmonary artery (PA) size, flow variables, and wall shear stress (WSS) in patients after Fontan operation ... Pulmonary artery size and function after fontan operation at a young age. Journal of Magnetic Resonance Imaging, 28(5), 1101- ...
Endoluminal Pulmonary Artery Banding: Technique, Applications and Results<...
N2 - Background: Occasionally pulmonary artery banding is necessary to reduce pulmonary arterial blood flow and pressure in ... AB - Background: Occasionally pulmonary artery banding is necessary to reduce pulmonary arterial blood flow and pressure in ... Background: Occasionally pulmonary artery banding is necessary to reduce pulmonary arterial blood flow and pressure in patients ... Endoluminal pulmonary artery banding alone is preferred when controlled pulmonary blood flow and cardiopulmonary bypass are ...
Residual shunt in an infant following patent ductus arteriosus ligation detected via transesophageal echocardiography...
The main pulmonary artery was finally strangulated using a 24-mm band, resulting in a peak pressure gradient of 41.9 mmHg at ... There was a discrete mosaic jet moving from the descending aorta toward the pulmonary artery (Fig. 1), suggesting incomplete ... Subsequently, when the surgeon was adjusting the diameter of band on the main pulmonary artery during PAB, TEE monitoring ... that decreased pulmonary arterial pressure caused by PAB greatly increased the pressure gradient between the pulmonary artery ...
Interventional treatment using a 3D model of a right pulmonary artery to left atrial fistula in an infant
This examination confirmed abnormal division of the right pulmonary artery into 2 vessels: the proper pulmonary artery and the ... Interventional treatment using a 3D model of a right pulmonary artery to left atrial fistula in an infant. Anna Wałdoch ... We present the case of a 3-month-old boy with a large right pulmonary artery to left atrial fistula successfully treated by ... The position of the device was stable and did not hinder the free insertion of the catheter into the right pulmonary artery ( ...
Failure of medical therapy for pulmonary "thromboembolic" disease: beware the unsuspected primary sarcoma of the pulmonary...
... beware the unsuspected primary sarcoma of the pulmonary artery.",. abstract = "Primary sarcoma of the pulmonary artery (PA) is ... Primary sarcoma of the pulmonary artery (PA) is rare. The diagnosis is difficult and often delayed. Two patients with primary ... N2 - Primary sarcoma of the pulmonary artery (PA) is rare. The diagnosis is difficult and often delayed. Two patients with ... AB - Primary sarcoma of the pulmonary artery (PA) is rare. The diagnosis is difficult and often delayed. Two patients with ...
Helical CT Evaluation Of Pulmonary Arteries
... And Aortopulmonary Collaterals In Pulmonary Atresia. Read more! ... CT, Publications > Helical CT Evaluation Of Pulmonary Arteries And Aortopulmonary Collaterals In Pulmonary Atresia. Our Blog. ... Helical CT Evaluation Of Pulmonary Arteries And Aortopulmonary Collaterals In Pulmonary Atresia. * 3rd July 2010 3/07/10 ... M. Srikanth,Singh J, Kalyanpur A. Helical Ct Evaluation Of Pulmonary Arteries And Aortopulmonary Collaterals In Pulmonary ...
Cangrelor Dosing and Monitoring for Prevention of Acute Systemic-to-Pulmonary Artery Shunt Thrombosis in Neonates | The Journal...
Cangrelor Dosing and Monitoring for Prevention of Acute Systemic-to-Pulmonary Artery Shunt Thrombosis in Neonates Pilar Anton- ... Systemic-to-pulmonary artery shunts are amongst the most common palliative procedures performed in neonates with congenital ... Ten neonates receiving cangrelor post systemic-to-pulmonary artery shunt placement were included in the study. Median age and ... Cangrelor Dosing and Monitoring for Prevention of Acute Systemic-to-Pulmonary Artery Shunt Thrombosis in Neonates Pilar Anton- ...
Contrast-enhanced doppler ultrasound for noninvasive assessment of pulmonary artery pressure during exercise in patients with...
Contrast-enhanced doppler ultrasound for noninvasive assessment of pulmonary artery pressure during exercise in patients with ... Noninvasive evaluation of pulmonary artery pressure during exercise by saline-enhanced Doppler echocardiography in chronic ... Noninvasive estimation of pulmonary artery diastolic pressure from spectral Doppler recordings of tricuspid and pulmonic ... Exercise ventilation and pulmonary artery wedge pressure in chronic stable congestive heart failure. American Journal of ...
HypertensionMain pulmonAortaEmbolismStenosisLungsMeasuring pulmonary artery pressureCongestive heart fRight ventricleMean pulmonaryMajor aortopulmonary collateral arteriesVeinAorticCardiacWedge pressureCollateral arteriesArterial pressureAneurysmVascular resistanceNormal pulmonary artery pressuresLung2022PatientsABSTRACTCongenital heart dProximalPressureStenosesAtresiaAneurysmsVeinsCardiopulmonary bypassEndothelial cellsCoronary arteriesFetalCOPDAtrialHypoxiaBloodDysfunctionObstructionAnomalous OriginSurgicalHeart
Hypertension62
- Pulmonary hypertension likely represents the majority of the cases of an elevated PA:A ratio, but other factors could also be responsible, such as heart failure, sleep apnea, thromboembolic disease, and obesity," he added. (medscape.com)
- This procedure helps protect the heart from working too hard and helps prevent pulmonary hypertension from developing over time. (childrens.com)
- By reducing extra blood flow to the lungs, the main pulmonary artery band protects the heart from working too hard and protects the lungs from developing pulmonary hypertension. (childrens.com)
- Marius M Hoeper, MD , is Associate Professor of Medicine in the Department of Pneumology at Hanover Medical School, Germany, where he is in charge of the pulmonary hypertension program and Director of the medical intensive care unit. (medscape.com)
- 1 Furthermore, the term 'pulmonary hypertension' is used imprecisely. (bmj.com)
- Pulmonary hypertension implies a pulmonary artery pressure higher than normal but whether this is systolic, diastolic, or mean has different connotations. (bmj.com)
- No patient experienced distal pulmonary hypertension, distortion, or band occlusion. (elsevier.com)
- A 6-month-old girl (2.7 kg) diagnosed with PDA, ventricular septal defect, and accompanying pulmonary hypertension was scheduled for PDA ligation and PAB. (springer.com)
- Pulmonary arterial hypertension (PAH) is characterized by pulmonary artery smooth muscle cell (PASMC) dysfunction. (aging-us.com)
- In particular, it would be useful if the relationship were maintained when treating pulmonary hypertension because this would allow different methods of measurement to be compared, such as SPAP from echocardiography and MPAP from right heart catheterization. (gla.ac.uk)
- Methods: Data were reviewed from both healthy subjects and those with pulmonary hypertension (n = 65) who had a micromanometer-tipped, high-fidelity pulmonary artery catheter inserted for between 6 and 36 h in the Scottish Pulmonary Vascular Unit between 1997 and 2003. (gla.ac.uk)
- Tadalafil is used to treat excessive blood stress inside the lungs (pulmonary hypertension). (fixrio.com)
- In this CritCases blog - a collaboration between STARS Air Ambulance Service, Mike Betzner and EM Cases we discuss a challenging case of pulmonary hypertension where a fine balance in volume resuscitation, oxygenation and ventilation is critical. (emergencymedicinecases.com)
- CT-determined pulmonary artery diameters in predicting pulmonary hypertension. (digiwire.co.in)
- This study was to determine if the diameters of pulmonary arteries measured from computed tomographic (CT) scans could be used 1) as indicators of pulmonary artery hypertension and 2) as a reliable base for calculating mean pulmonary artery pressure. (digiwire.co.in)
- In these patients, a diameter of the main pulmonary artery above 28.6 mm readily predicted the presence of pulmonary hypertension. (digiwire.co.in)
- Because CT allows precise, noninvasive measurement of the diameter of pulmonary arteries, it can be of value in detecting pulmonary hypertension and estimating mean pulmonary artery pressure. (digiwire.co.in)
- A CT sign of chronic pulmonary arterial hypertension: the ratio of main pulmonary artery to aortic diameter. (digiwire.co.in)
- The aim of this study was to determine whether the ratio of the diameters of the main pulmonary artery and of the ascending aorta (rPA), as assessed on computed tomography (CT), is predictive of pulmonary arterial hypertension (PAH). (digiwire.co.in)
- Idiopathic pulmonary arterial hypertension (IPAH) is a rare disease characterized by elevated pulmonary artery pressure with no apparent cause. (medscape.com)
- IPAH is also termed WHO Group I pulmonary hypertension (PH), precapillary pulmonary hypertension, and, previously, primary pulmonary hypertension. (medscape.com)
- In approximately a third of patients with pulmonary arterial hypertension (PAH), Doppler echocardiography demonstrates right-to-left shunting across a patent foramen ovale. (medscape.com)
- Chest radiography: A chest radiograph may help identify secondary causes of, or contributors to, pulmonary hypertension. (medscape.com)
- Equally important, the echocardiogram helps to exclude secondary causes of, or contributors to, pulmonary hypertension, such as left-sided heart disease (eg, left ventricular dysfunction, valvular heart disease). (medscape.com)
- Nuclear lung ventilation/perfusion scanning: This is performed to exclude chronic thromboembolic pulmonary hypertension (Group IV PH). (medscape.com)
- Pulmonary hypertension is high blood pressure in the arteries of the lungs. (stlukes-stl.com)
- I. Pulmonary Hypertension: What every physician needs to know. (renalandurologynews.com)
- Pulmonary hypertension is defined as mean pulmonary arterial pressure of 25 mm Hg or greater. (renalandurologynews.com)
- Pulmonary hypertension therefore is a description rather than a diagnosis. (renalandurologynews.com)
- Once pulmonary hypertension is detected, careful diagnostic steps are necessary to ensure accurate diagnosis, followed by appropriate evidence-based treatment. (renalandurologynews.com)
- Despite the growth in the field of pulmonary hypertension, in particular with expansion of available medical therapeutics, we need to recognize that these therapeutics are only indicated for a specific subtype of pulmonary hypertension. (renalandurologynews.com)
- Accordingly, detection of elevated pulmonary artery pressure should not immediately result in treatment, but instead lead to an additional and careful diagnostic workup, including confirmation of the presence of pulmonary hypertension. (renalandurologynews.com)
- Diagnostic Confirmation: Are you sure your patient has Pulmonary Hypertension? (renalandurologynews.com)
- Pulmonary hypertension is often first suspected or discovered by echocardiography. (renalandurologynews.com)
- Despite advances in echocardiography, pulmonary hypertension still requires a right heart catheterization (RHC) demonstrating mean pulmonary arterial pressure ≥ 25 mm Hg at rest for confirmation. (renalandurologynews.com)
- For patients with World Health Organization (WHO) group I cause of pulmonary hypertension, also known as pulmonary arterial hypertension (PAH), the Pawp should be less than 15 mm Hg. (renalandurologynews.com)
- This is primarily to rule out the more common secondary pulmonary hypertension related to various left heart conditions or pulmonary venous hypertension-PH classified under WHO group II. (renalandurologynews.com)
- The history of PAH can be traced back to the aminorex (diet pill) epidemic in Europe causing primary pulmonary hypertension (PPH, the prior term for what we now call idiopathic pulmonary arterial hypertension) back in the 1960s and 70s. (renalandurologynews.com)
- Fast forwarding to the current era, the typical PAH patient tends to be older and with other comorbidities either linking with pulmonary hypertension or challenging its timely diagnosis and treatment. (renalandurologynews.com)
- PAH remains a rare condition and infrequent cause of pulmonary hypertension detected by echocardiogram. (renalandurologynews.com)
- C. History Part 3: Competing diagnoses that can mimic Pulmonary Hypertension? (renalandurologynews.com)
- If we were to start with pulmonary hypertension detected by echocardiogram, then the most common causes of pulmonary hypertension at the end of our workup are also the common conditions we see on a regular basis. (renalandurologynews.com)
- In other words, common things are common-with pulmonary hypertension related to left heart condition (WHO group II) or chronic lung disease/hypoxemia (WHO group III) being the two most common causes of pulmonary hypertension. (renalandurologynews.com)
- The various diagnostic algorithms for pulmonary hypertension have been designed with this important recognition. (renalandurologynews.com)
- Another major and unique cause of pulmonary hypertension worthy of a separate classification group is chronic thromboembolic pulmonary hypertension (CTEPH, WHO group IV). (renalandurologynews.com)
- Risk factors for pulmonary arterial hypertension in systemic sclerosis. (medpagetoday.com)
- Borderline elevation of mean pulmonary artery pressure (BoPAP) -- 21 to 24 mm Hg -- may represent an intermediate stage between normal pulmonary artery pressures and pulmonary arterial hypertension (PAH) in patients with systemic sclerosis, researchers stated. (medpagetoday.com)
- 60% predicted, and no prior diagnosis of pulmonary hypertension. (medpagetoday.com)
- Patients eligible for the current study had a pulmonary artery wedge pressure (PAWP) ≤15 mm Hg, no significant interstitial lung disease, no systemic hypertension, and no left atrial enlargement. (medpagetoday.com)
- Pulmonary hypertension (PH) is an uncommon but progressive condition. (cdc.gov)
- Congestive heart failure can also occur when the right ventricle is unable to overcome increased pressure in the pulmonary artery, which usually results from left heart failure, chronic lung disease or high blood pressure in the pulmonary artery (pulmonary hypertension). (lynchspharmacy.com)
- Positive Topline Data for Sotatercept in PAH: STELLAR Sotatercept added to standard therapy led to improves exercise capacity in adults with pulmonary arterial hypertension in a phase 3 trial. (medscape.com)
- ESC 2022 New ESC Pulmonary Hypertension Guidelines Urge Earlier Diagnosis The diagnostic algorithm has been revamped and clinicians should be thinking of arterial hypertension at an earlier (lower) arterial pulmonary pressure, the authors say. (medscape.com)
- TCT 2022 Pulmonary Artery Denervation Takes Next Step in Hypertension A sham-controlled trial in this progressive, often debilitating disease showed patients treated with a radiofrequency device had longer 6-minute walk times and other benefits. (medscape.com)
- Biomarker Predicts Survival in Pulmonary Arterial Hypertension Plasma cell-free DNA, a marker of cellular injury, is elevated in patients with pulmonary arterial hypertension, correlates with disease severity, and predicts worse survival, new research shows. (medscape.com)
- Identifying Severe Pulmonary Hypertension in Patients With COPD Patients with COPD and severe pulmonary hypertension may benefit from individualized treatment. (medscape.com)
- Patients With More Severe PH in COPD May Respond to Treatment Male sex, low 6-minute walking distance, and high pulmonary vascular resistance at baseline were predictive of poorer outcomes for pulmonary hypertension and COPD. (medscape.com)
- b) Hypertension, Coronary artery disease. (bankofbiology.com)
- This can also lead to pulmonary gland hypertension, making someone feel anxious and claustrophobic. (eonlinepharmacystore.com)
- Persistent pulmonary arterial hypertension can be treated with various pulmonary vasodilators such as inhaled nitric oxide and sildenafil, and endothelin receptor inhibitors such as bosentan. (medscape.com)
- Different kinds of echo and how diseases like congenital heart disease, pulmonary hypertension, and coronary artery diseases etc. (allbooks.net)
- Cardiac disease secondary to occupational lung disease was a result of pulmonary hypertension. (cdc.gov)
Main pulmon21
- Our heart surgeons have the skill and experience to know when a main pulmonary artery band will benefit a child. (childrens.com)
- The main pulmonary artery band creates a narrowing of the main pulmonary artery to reduce blood flow to the lungs and decrease pulmonary artery pressure. (childrens.com)
- What are the benefits of Pediatric Main Pulmonary Artery Band? (childrens.com)
- For some babies waiting for surgery, the main pulmonary artery band may make it possible for them to go home before the next operation. (childrens.com)
- What are the risks of Pediatric Main Pulmonary Artery band? (childrens.com)
- Your baby will probably outgrow the main pulmonary artery band in 3 to 10 months. (childrens.com)
- What to expect with Pediatric Main Pulmonary Artery band? (childrens.com)
- The surgeons will open the sternum to insert the band around the main pulmonary artery. (childrens.com)
- What questions should I ask my provider about Pediatric Main Pulmonary Artery Band? (childrens.com)
- Will my child be able to go home after getting a main pulmonary artery band? (childrens.com)
- Endoluminal pulmonary artery banding fenestrations of 2 to 8 mm were centrally placed in a Dacron patch that was attached circumferentially and intraluminally in the main pulmonary artery. (elsevier.com)
- Subsequently, when the surgeon was adjusting the diameter of band on the main pulmonary artery during PAB, TEE monitoring revealed a residual PDA shunt on color Doppler imaging. (springer.com)
- The main pulmonary artery was finally strangulated using a 24-mm band, resulting in a peak pressure gradient of 41.9 mmHg at the PAB site when the systemic arterial pressure was 74/45 mmHg. (springer.com)
- Dextro-Transposition (pronounced DECKS-tro trans-poh-ZI-shun) of the Great Arteries or d-TGA is a birth defect of the heart in which the two main arteries carrying blood out of the heart - the main pulmonary artery and the aorta - are switched in position, or "transposed. (cdc.gov)
- Dextro-Transposition of the Great Arteries or d-TGA is a birth defect of the heart in which the two main arteries carrying blood out of the heart - the main pulmonary artery and the aorta - are switched in position, or "transposed. (cdc.gov)
- Oxygen-rich blood from the lungs entering the heart is pumped straight back to the lungs through the main pulmonary artery. (cdc.gov)
- The procedure involves placement of an extracardiac conduit between the right ventricle and main pulmonary artery stump. (diaridelsestudiants.com)
- The upper limit of normal diameter for the main pulmonary artery was found to be 28.6 mm (mean + 2 SD). (digiwire.co.in)
- Multiple regression analysis gave the useful equation: mean pulmonary artery pressure = -10.92 + 0.07646 X area of main pulmonary artery/BSA + 0.08084 X area of thright interlobar pulmonary artery/BSA (r = 0.93, P less than 0.0001). (digiwire.co.in)
- Two independent observers made measurements of the diameter of the main pulmonary artery and of the ascending aorta on a single defined CT section. (digiwire.co.in)
- Video 11-1-2: 2-D image on TTE of a large embolism in the main pulmonary artery in the parasternal short-axis view. (mhmedical.com)
Aorta22
- September 28, 2012 (Vienna, Austria) - The ratio of the diameter of the pulmonary artery to the diameter of the aorta is a metric that not only indicates arterial enlargement and possible pulmonary disease, it also identifies patients with chronic obstructive pulmonary disease (COPD) who are at risk of experiencing an exacerbation, a new study suggests. (medscape.com)
- In a healthy heart, both the left and right coronary arteries branch off the aorta. (nemours.org)
- The aorta is the major artery that carries this oxygen-rich blood from the heart to the rest of the body. (nemours.org)
- The pulmonary arteries are the second most common site of arterial involvement after the aorta. (who.int)
- There was a discrete mosaic jet moving from the descending aorta toward the pulmonary artery (Fig. 1 ), suggesting incomplete PDA ligation. (springer.com)
- We believe that decreased pulmonary arterial pressure caused by PAB greatly increased the pressure gradient between the pulmonary artery and the descending aorta, which made the residual PDA shunt detectable in our case. (springer.com)
- In transposition of the great arteries, the aorta is in front of the pulmonary artery and is either primarily to the right (dextro) or to the left (levo) of the pulmonary artery. (cdc.gov)
- The aorta is usually behind the pulmonary artery. (cdc.gov)
- Instead of coming from the pulmonary trunk, supply develops from the aorta and other systemic arteries. (diaridelsestudiants.com)
- Major aortopulmonary collateral arteries (MAPCAs) are persistent tortuous fetal arteries that arise from the descending aorta and supply blood to pulmonary arteries in the lungs usually at the posterior aspect of hilum. (diaridelsestudiants.com)
- The Takeuchi procedure involves creation of an aortopulmonary window and an intrapulmonary tunnel that baffles the aorta to the ostium of the anomalous left coronary artery. (diaridelsestudiants.com)
- In this technique, the collateral vessels supplying blood from the aorta directly to the lungs are brought into continuity in a single vessel that supplies the pulmonary circulation usually via a conduit from the right ventricle or a shunt. (diaridelsestudiants.com)
- The model includes whole heart as well as following seven heart structures: left and right ventricles, left and right atrium, myocardium, aorta, and pulmonary artery. (embodi3d.com)
- It includes 7 parts including the aorta, left and right atrium, left and right ventricles, and pulmonary artery. (embodi3d.com)
- ABSTRACT The anomalous origin of one pulmonary artery from the ascending aorta is a rare congenital heart disease , generally diagnosed based on the clinical information and on echocardiographic and computed tomography angiography findings. (bvsalud.org)
- This second pump, the 'left heart,' receives the blood from the lungs during contraction, pumps it out through the great artery called the aorta. (cdc.gov)
- The aorta branches out to supply the entire body with blood through a series of arteries. (cdc.gov)
- The oxygen-rich blood then returns to the left atrium through the pulmonary veins, flows through the mitral valve into the left ventricle, and finally leaves your heart through another large artery, the aorta. (lynchspharmacy.com)
- Blood Flow Away from the Heart With each rhythmic pump of the heart blood is pushed under high pressure and velocity away from the heart initially along the main artery the aorta. (medbeautys.com)
- From the aorta blood flows into the arteries and arterioles and ultimately to the capillary beds. (medbeautys.com)
- Blood then flows to the pulmonary artery and aorta. (panayiotidescardio.com)
- The aorta, which is the body's largest artery, carries oxygen-rich blood to the rest of your body. (panayiotidescardio.com)
Embolism11
- The HRCT imaging showed signs of chronic pulmonary embolism of the left pulmonary artery with infarction formation, which was confirmed with VP scan. (ersjournals.com)
- Over-insertion of a pulmonary artery catheter (PAC) can cause serious complications, such as pulmonary embolism and pulmonary artery rupture. (lupinepublishers.com)
- However, if left untreated, DVT can result in a pulmonary embolism, which occurs when the blood clot travels from the leg to the lungs. (cnn.com)
- IVC filters are implanted in the body in an effort to prevent pulmonary embolism, in which blood flow in the arteries is blocked by air or blood clots. (waterskraus.com)
- Bikdeli and his colleagues studied 556,658 Medicare beneficiaries admitted to the hospital between 1999 and 2010 for pulmonary embolism. (waterskraus.com)
- The researchers reportedly learned that more than 15 percent of the Medicare patients received an IVC filter to treat pulmonary embolism. (waterskraus.com)
- In 1999, the number of hospitalizations for pulmonary embolism in which IVC filters were used was 5,003. (waterskraus.com)
- During the same time period, the number of deaths from pulmonary embolism went down, whether or not patients had been implanted with an IVC filter. (waterskraus.com)
- The use of IVC filters to treat pulmonary embolism is expensive. (waterskraus.com)
- Indeed, Bikdeli noted, IVC filter procedures are not without complications and do not always succeed in preventing pulmonary embolism. (waterskraus.com)
- That creates what's called a pulmonary embolism (PE). (medlineplus.gov)
Stenosis19
- Kwak JG, Kim WH, Min J, Lee C, Jang W, Lee CH. Is tracheoplasty necessary for all patients with pulmonary artery sling and tracheal stenosis? (medscape.com)
- E ditor ,-We read with interest this report of peripheral pulmonary artery stenosis in congenital generalised lipodystrophy but query the physical findings, particularly in case 1. (bmj.com)
- In peripheral pulmonary artery stenosis, both are low, analogous to the situation after pulmonary artery banding to reduce pulmonary blood flow in certain congenital cardiac defects. (bmj.com)
- We were surprised at Drs Carvalho and Shinebourne's comments on clinical signs in patients with peripheral pulmonary stenosis-they state that pulmonary artery diastolic pressure is low in these patients and that the pulmonary component of the second heart sound is, therefore, not accentuated (as it was in one of our cases). (bmj.com)
- Stenosis, Pulmonary Artery" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (musc.edu)
- This graph shows the total number of publications written about "Stenosis, Pulmonary Artery" by people in this website by year, and whether "Stenosis, Pulmonary Artery" was a major or minor topic of these publications. (musc.edu)
- Below are the most recent publications written about "Stenosis, Pulmonary Artery" by people in Profiles. (musc.edu)
- Commentary: Branch pulmonary artery stenosis after the arterial switch operation: Is prevention better than cure? (musc.edu)
- Rhodes JF, Jackson L. Tipping Point: When Does Unilateral Branch Pulmonary Artery Stenosis Impede Exertional Performance? (musc.edu)
- First described by Elliotson, infundibular pulmonary stenosis (IPS) refers to obstruction of outflow from the right ventricle (RV) within the body of the RV, as opposed to obstruction at the pulmonary valve, pulmonary artery (PA), or its branches. (medscape.com)
- In this article, IPS refers to isolated infundibular pulmonary stenosis with an intact ventricular septum. (medscape.com)
- Infundibular pulmonary stenosis (IPS) has two forms. (medscape.com)
- Such reversal and cyanosis can occur when the RV is hypoplastic, even with less severe pulmonary stenosis. (medscape.com)
- In neonates with severe pulmonary stenosis, the pulmonary blood flow depends on the patency of the ductus arteriosus. (medscape.com)
- Patients with isolated valvular pulmonary stenosis may have a reactive infundibular hypertrophy that could elicit a reactive infundibular obstruction. (medscape.com)
- The prognosis of infundibular pulmonary stenosis (IPS) mainly depends on the severity of stenosis in the absence of any additional lesions. (medscape.com)
- Cataracts/congenital glaucoma, congenital heart disease (most commonly patent ductus arteriosus or peripheral pulmonary artery stenosis), hearing impairment, pigmentary retinopathy. (cdc.gov)
- Transesophageal echocardiography was used in 1 patient and did not detect a right pulmonary artery stenosis. (northumbria.ac.uk)
- One patient underwent revision of a pulmonary artery stenosis with a period of warm ischemia and subsequent fatal lung injury. (northumbria.ac.uk)
Lungs22
- The pulmonary arteries take blood from the heart to the lungs. (medlineplus.gov)
- The pediatric cardiac care team at Children's Health can surgically place a small band around the main artery leading to the lungs to limit the amount of blood. (childrens.com)
- Sometimes a pulmonary artery band is placed in a child whose heart has only one pumping chamber (called a single ventricle heart) to protect their lungs while the child waits for the next stage of relief for their symptoms. (childrens.com)
- Pulmonary vascular disease is the general term for conditions affecting the blood vessels that go between the heart and lungs and supply the blood with oxygen. (choa.org)
- The causes and kinds of pulmonary vascular disease can vary depending on which of the lungs' blood vessels are affected. (choa.org)
- At post mortem examination, the lungs failed to collapse and were enlarged and heavy with multifocal to coalescing subpleural pearly-white nodules, located in diaphragmatic pulmonary lobes ( figure 1A ). (scielo.cl)
- In a heart with anomalous (abnormal) origin of the pulmonary artery, the left or right coronary arteries branch off the pulmonary artery and carries blood from the heart to the lungs instead. (nemours.org)
- In a baby without a congenital heart defect, the right side of the heart pumps oxygen-poor blood from the heart to the lungs through the pulmonary artery. (cdc.gov)
- PAC manufacturer instructions state that the best position for the tip is at the hilum of the lungs in the right pulmonary artery (see Additional file 1, p. 148). (lupinepublishers.com)
- A surgery called unifocalization, performed soon after birth, can reroute the MAPCAs into the pulmonary artery in addition to repairing the Tetralogy of Fallot, restoring normal circulation from the lungs to the heart. (diaridelsestudiants.com)
- April 2012) Major aortopulmonary collateral arteries (or MAPCAs) are arteries that develop to supply blood to the lungs when native pulmonary circulation is underdeveloped. (diaridelsestudiants.com)
- The 'right heart,' during contraction, pumps the blood to the lungs via the pulmonary artery. (cdc.gov)
- Swan-Ganz catheterization is the passing of a thin tube (catheter) into the right side of the heart and the arteries leading to the lungs. (stlukes-stl.com)
- PH occurs when the blood pressure in the pulmonary arteries, which carry oxygen and blood from the heart to the lungs, is much higher than normal. (cdc.gov)
- Pulmonary oedema is a condition caused by excess fluid in the lungs. (lynchspharmacy.com)
- A number of things can cause fluid to accumulate in your lungs, but most have to do with your heart (cardiac pulmonary edema). (lynchspharmacy.com)
- Normally, deoxygenated blood from all over your body enters the right atrium and flows into the right ventricle, where it's pumped through large blood vessels (pulmonary arteries) to your lungs. (lynchspharmacy.com)
- Cardiac pulmonary oedema - also known as congestive heart failure - occurs when the diseased or overworked left ventricle isn't able to pump out enough of the blood it receives from your lungs. (lynchspharmacy.com)
- The pulmonary artery carries blood to the lungs where it picks up oxygen and then leaves the lungs to return to the heart through the pulmonary vein. (medbeautys.com)
- Blood flow away from the heart AB A C. Blood leaves the heart through the pulmonic valve into the pulmonary artery and flows to the lungs. (medbeautys.com)
- The pulmonary artery carries deoxygenated blood from the heart to the lungs. (panayiotidescardio.com)
- Sometimes they travel to an artery in the lungs and block blood flow. (medlineplus.gov)
Measuring pulmonary artery pressure1
- The pulmonary artery catheter (PAC) is used for many diagnostic applications, including measuring pulmonary artery pressure, cardiac output, and mixed venous oxygen saturation [1]. (lupinepublishers.com)
Congestive heart f4
- Pulmonary artery pressure response to exercise was assessed using contrast enhancement of tricuspid regurgitation peak velocities in 19 patients with chronic congestive heart failure. (eurekamag.com)
- Common conditions meeting home oxygen requirements include congestive heart failure and chronic obstructive pulmonary disease (COPD) . (lincare.com)
- Rapid weight gain when pulmonary oedema develops as a result of congestive heart failure, a condition in which your heart pumps too little blood to meet your body's needs. (lynchspharmacy.com)
- Heart disease (such as congenital heart helpful, especially if the sick person is in a group at high risk for serious disease, congestive heart failure, and coronary complications (see list in sidebar) or is very sick from flu (for example, artery disease) hospitalized from flu). (cdc.gov)
Right ventricle4
- In unifocalization, the misdirected blood vessels are rerouted into a single vessel (or into the pulmonary artery if it is present), which is then attached to the right ventricle of the heart through a conduit called a homograft. (diaridelsestudiants.com)
- Typically, the echocardiogram demonstrates evidence of increased pulmonary arterial (PA) pressure, accompanied by an enlarged right ventricle (see the image below). (medscape.com)
- When Lillian was born, her pulmonary artery did not reach the right ventricle of her heart. (biobridgeglobal.org)
- PHENOTYPE: Homozygotes exhibit double outlet right ventricle {SDD}, pulmonary atresia/hypolastic pulmonary artery, atrioventricular septal defect, and right aortic arch. (utsouthwestern.edu)
Mean pulmonary4
- Background: The relationships among systolic pulmonary artery pressure (SPAP), diastolic pulmonary artery pressure (DPAP), and mean pulmonary artery pressure (MPAP) have been found to be constant in humans breathing air, at rest, while supine. (gla.ac.uk)
- The calculated cross-sectional areas of the main and interlobar pulmonary arteries (normalized for body surface area [BAS]) were found to give the best estimates of mean pulmonary artery pressure (r = 0.89, P less than 0.001 and r = 0.66, P less than 0.001). (digiwire.co.in)
- In 175 patients with chronic obstructive lung disease (157 chronic bronchitic and 18 emphysematous patients) exhibiting moderate to severe airway obstruction (mean FEV1/vital capacity = 40.2 +/- 11.1%), cumulative survival rates calculated by the actuarial method were compared in subgroups according to the initial level of mean pulmonary artery pressure, pulmonary volumes, and arterial blood gases. (digiwire.co.in)
- A subanalysis of a large multicenter study of systemic sclerosis (SSc) patients at risk for PAH found clinical and laboratory features that may differentiate patients with BoPAP from those with normal mean pulmonary artery pressure (mPAP) and PAH, according to Scott H. Visovatti, MD , of the University of Michigan in Ann Arbor, and colleagues. (medpagetoday.com)
Major aortopulmonary collateral arteries3
- This program treats patients with the diagnosis of major aortopulmonary collateral arteries (MAPCAs), isolated pulmonary artery of ductal origin (IPADO), pulmonary vascular disease associated with Alagille syndrome and Williams syndrome, and other difficult pulmonary artery surgical repairs. (choa.org)
- What are major Aortopulmonary collateral arteries? (diaridelsestudiants.com)
- A unifocalisation procedure is a corrective surgical technique used in patients with complete pulmonary artery atresia with major aortopulmonary collateral arteries (MAPCAs). (diaridelsestudiants.com)
Vein8
- This examination confirmed abnormal division of the right pulmonary artery into 2 vessels: the proper pulmonary artery and the vessel leading to a 21 × 10 mm reservoir, which then in the place of the lower right pulmonary vein escaped through a wide opening (11 mm) into the left atrium. (termedia.pl)
- Approximately 90% of injuries occur at the medial and inferior branches of the right pulmonary artery, because a PAC inserted from the right internal jugular vein will most often enter the right pulmonary artery [2]. (lupinepublishers.com)
- Participants were patients in whom a PAC was inserted from the right internal jugular vein to the main or right pulmonary artery and who underwent surgery using cardiopulmonary bypass in the supine position. (lupinepublishers.com)
- Differentiate between pulmonary artery and pulmonary vein. (pathshalanepal.com)
- The blood then returns to the 'left heart' via the pulmonary vein. (cdc.gov)
- for fixing multi-lumen catheter,pulmonary artery catheter,hemodialysis catheter,jujuakar vein and carotiod catheter. (medicalwounddressing.com)
- Video 10-3-1: Two-dimensional multiplanar TEE image at 75° in the mid-esophagus, showing the left atrium, left atrial appendage, left ventricle, and left upper pulmonary vein. (mhmedical.com)
- Its duet ' or vesical artery vein of the anterior tuberosity. (wildwoodclinic.com)
Aortic4
- Morrow R, Huhta J. Aortic arch and pulmonary artery anomalies. (medscape.com)
- Body surface area (BSA, n = 48), pulmonary arteriolar resistance (n = 39), total lung capacity (n = 40), and aortic pressures (n = 50) were also recorded. (digiwire.co.in)
- Once the ventricles have filled with blood, they begin to contract, forcing the pulmonary and aortic valves to open. (panayiotidescardio.com)
- This 11th IARC Handbook of Cancer Prevention, and the first in a series focusing on Tobacco Control, presents a comprehensive review of the scientific literature and a thorough evaluation, made by an international group of experts, of the evidence for changes in the risk of cancer, coronary heart disease, cerebrovascular disease, abdominal aortic aneurysm, peripheral artery disease and chronic obstructive pulmonary disease observed following smoking cessation. (who.int)
Cardiac3
- We describe our technique, applications, and results of endoluminal pulmonary artery banding (EPAB) with and without creation of an aortopulmonary window (APW) for complex cardiac anomalies. (elsevier.com)
- Coronary artery bypass grafting (CABG) is performed for patients with coronary artery disease (CAD) to improve quality of life and reduce cardiac-related mortality. (medscape.com)
- The death certificate, completed by the county chief deputy coroner, and the autopsy report, completed by the pathologist, listed "cardiac dysrhythmia due to atherosclerotic coronary artery disease and myocardial bridging of anterior descending coronary artery" as the cause of death. (cdc.gov)
Wedge pressure4
- PCWP: pulmonary capillary wedge pressure. (lupinepublishers.com)
- When waveform obtained from the tip of the PAC with the balloon inflated shows correct pulmonary capillary wedge pressure (PCWP), the tip must be in the pulmonary artery, and the balloon is deflated. (lupinepublishers.com)
- A second critical information from the RHC that is central to the diagnosis is the pulmonary arterial occlusion or wedge pressure (Pawp). (renalandurologynews.com)
- Intravenous injection of KETANSERIN TARTRATE can reduce the right atrial pressure, pulmonary artery pressure and pulmonary capillary wedge pressure. (avolsenchem.com)
Collateral arteries1
- Two-thirds of the cases with PA are associated with major aorto pulmonary collateral arteries (MAPCAs). (telradsol.com)
Arterial pressure1
- We undertook a retrospective review of 50 patients with a wide range of pulmonary and cardiovascular diseases, who had undergone both chest CT and pulmonary arterial pressure measurements at right heart catheterization. (digiwire.co.in)
Aneurysm5
- Aneurysm of the pulmonary artery is a rare condition in animals, and to our knowledge it has never been reported in association with pulmonary neoplasia. (scielo.cl)
- This report describes a case of an adult female sheep of the "Churra Galega Bragançana" breed with an aneurysm of the pulmonary artery associated with lung cancer (ovine pulmonary adenocarcinoma). (scielo.cl)
- The pulmonary artery had a focal dilatation at base of ~ 2.5 cm, interpreted as aneurysm, apparently with reduced wall thickness ( figure 1C ). (scielo.cl)
- Surgical repair of pulmonary artery aneurysm in BD carries a high risk, with high rates of morbidity and mortality [11]. (who.int)
- The final diagnosis was a solitary peripheral pulmonary artery saccular aneurysm. (sumarios.org)
Vascular resistance1
- The intensity of the pulmonary component of the second heart sound depends primarily on the pulmonary artery diastolic pressure dependent in turn on pulmonary vascular resistance. (bmj.com)
Normal pulmonary artery pressures1
- In many cases, they have normal pulmonary artery pressures and healthy ventricles, with full repair of their vascular disease. (choa.org)
Lung10
- Left pulmonary artery sling presenting as unilateral echogenic lung on 20-week detailed antenatal ultrasound examination. (medscape.com)
- Our program is unique because our team uses surgical techniques to treat complex areas of pulmonary vascular disease well past the midpoint of the lung, where the pulmonary vessels and arteries enter and leave, to perform high-quality surgical repairs, and we provide close surveillance over time. (choa.org)
- Radiography revealed a nodular pattern with small and diffuse nodules in the pulmonary parenchyma and a larger lesion in the cause-dorsal lung field. (scielo.cl)
- We evaluated the sheep pulmonary artery (PA) for the presence or absence of a septum, which may increase PA resistance and affect artificial lung flow. (utmb.edu)
- We describe a case of pulmonary artery (PA) pseudoaneurysm related to radiofrequency ablation (RFA) of lung tumor. (elsevier.com)
- Microwave Ablation of the Lung in a Porcine Model: Vessel Diameter Predicts Pulmonary Artery Occlusion. (jefferson.edu)
- Since chronic lung disease is common in survivors of pulmonary hypoplasia, these infants and children have an increased risk of fatality and serious morbidity from upper respiratory tract infections (URTIs) and lower respiratory tract infections (LRTIs). (medscape.com)
- The fetal lung 2: Pulmonary hypoplasia. (medscape.com)
- To test this, we investigated the relationship between acute brain ischemia, lung inflammation, and CNS reperfusion injury in the middle cerebral artery occlusion (MCAO) model of stroke. (rochester.edu)
- We retrospectively identified 5 of 109 consecutive patients undergoing lung transplantation who had postopreative pulmonary arterial or venous obstruction. (northumbria.ac.uk)
20221
- ERS 2022 Hybrid ERS Congress 2022 a Breath of Fresh Air The hybrid meeting promises education, collaboration, and curbside consults for professionals in pulmonary and critical care medicine. (medscape.com)
Patients16
- In an accompanying editorial , Matthew B. Stanbrook, MD, PhD, from the Asthma and Airway Centre of the University Health Network at the University of Toronto in Ontario, Canada, notes that there are existing medications that are expected to reduce the risk for exacerbations in patients with COPD, but there is no evidence that they will work in patients with increased artery size. (medscape.com)
- In patients with pulmonary artery sling, the history is predictable and usually not subtle. (medscape.com)
- These specialists meet regularly to discuss all of the important aspects of care for our patients with pulmonary vascular disease. (choa.org)
- In the Pulmonary Artery Reconstruction Program, we are a team with one goal in mind: to make our patients as healthy as possible and help them remain that way for the rest of their lives. (choa.org)
- Patients in our Pulmonary Artery Reconstruction Program are often able to lead normal lives after treatment. (choa.org)
- This may indeed be the case in some patients with a limited number of discrete pulmonary artery stenoses (diastolic pressure being low because of flow occurring through the low resistance vessels which are unaffected by the disease). (bmj.com)
- Aneurysms associated with BD tend to be multiple and pulmonary artery aneurysms are relatively common, with an associated rate of 1%-10% of patients with BD [9]. (who.int)
- Purpose: To assess pulmonary artery (PA) size, flow variables, and wall shear stress (WSS) in patients after Fontan operation at a young age. (eur.nl)
- Background: Occasionally pulmonary artery banding is necessary to reduce pulmonary arterial blood flow and pressure in patients who cannot be repaired in a single stage. (elsevier.com)
- Two patients with primary sarcoma of the PA that mimicked pulmonary thromboembolic diseases who presented with complications requiring surgical intervention are described. (monash.edu)
- The diameters of the main, left, proximal right, distal right, interlobar, and left descending pulmonary arteries were measured from CT scans in 32 patients with cardiopulmonary disease and in 26 age- and sex-matched control subjects. (digiwire.co.in)
- Certain other parameters ("driving" pressure across the pulmonary circulation, FEV1 and Paco2) appear to be equally good at predicting survival as PAP in these obstructed patients. (digiwire.co.in)
- In 64 patients who underwent a second right heart catheterisation at least three years after the first (average delay: 5.5 +/- 2 years), the prognostic value of changes in PAP, arterial blood gases, and pulmonary volumes was studied but with the exception of Pao2 was unremarkable. (digiwire.co.in)
- Mean TPG and DWG measurements in the BoPAP group were intermediate between those in the normal PAP and PAH groups, leading the investigators to suggest that a subset of systemic sclerosis patients with BoPAP may have early pulmonary vasculopathy. (medpagetoday.com)
- In Long COVID, CPET Finds Abnormalities Other Tests Don't Dysfunctional breathing, hypocapnia, and myalgic encephalomyelitis/chronic fatigue syndrome were seen in symptomatic patients post-acute COVID-19 despite normal chest imaging and pulmonary function. (medscape.com)
- provide a rigorous summary of the available evidence on pulmonary histopathological findings in patients with COVID-19. (bvsalud.org)
ABSTRACT1
- abstract = "Primary sarcoma of the pulmonary artery (PA) is rare. (monash.edu)
Congenital heart d1
- Tetrology of Fallot (TOF) comprises 3.9% of congenital heart disease,[1] of which approximately 5-10% have pulmonary atresia (PA) with ventricular septal defect (VSD). (telradsol.com)
Proximal5
- In contrast, when there are multiple severe peripheral pulmonary artery stenoses and a paucity of low resistance vessels remaining then diastolic pressure in the proximal pulmonary arteries rises and the pulmonary second sound may be accentuated, as described in our report 1-1 (our patient's pressure was 85/30 with mean of 55 mm Hg). (bmj.com)
- In rings of pulmonary artery suspended for isometric tension recording (37°C, 16% O 2 and 5% CO 2 ), moderate hypoxia (10% and 4% O 2 ) caused endothelium-dependent relaxation in distal arteries but transient endothelium-dependent contraction in proximal arteries. (elsevier.com)
- In both proximal and distal arteries, the initial response to anoxia (0% O 2 ) was a transient endothelium-dependent contraction. (elsevier.com)
- This was followed by a slowly developing, sustained endothelium-dependent contraction in proximal arteries, or by an endothelium-independent relaxation in distal arteries. (elsevier.com)
- Transient endothelium-dependent contractions to moderate hypoxia (proximal arteries) or anoxia (all arteries) were abolished by L- NAME, but the late endothelium-dependent anoxic contraction observed in proximal arteries was not reduced by L-NAME and/or indomethacin. (elsevier.com)
Pressure10
- If the pulmonary artery diastolic pressure is high, the pulmonary component of the second sound is likely to be accentuated. (bmj.com)
- We suggest that, in surgery for PDA closure in combination with PAB, the existence of residual PDA shunt flow should be evaluated again after the pulmonary artery pressure decreases with banding. (springer.com)
- Prognostic value of pulmonary artery pressure in chronic obstructive pulmonary disease. (digiwire.co.in)
- Enough air pressure is pumped into the cuff to close the artery. (cdc.gov)
- When the pressure in the cuff is equal to the pressure on the artery, the artery opens and the blood begins to return to the part of the artery that was closed. (cdc.gov)
- The cuff is connected by tubing to a manometer, which shows the amount of pressure on the artery. (cdc.gov)
- Elevation of pulmonary pressure can be caused by a wide range of conditions with very different prognoses and treatment implications. (renalandurologynews.com)
- As a result, pressure increases inside the left atrium and then in the pulmonary veins and capillaries, causing fluid to be pushed through the capillary walls into the air sacs. (lynchspharmacy.com)
- Ventricular contraction ejects blood into the major arteries resulting in flow from regions of higher pressure to regions of lower pressure as blood encounters smaller arteries and arterioles then capillaries then the venules and veins of the venous system. (medbeautys.com)
- Blood arteries constrict due to this illness, making the heart work harder to pump blood and raise blood pressure levels. (eonlinepharmacystore.com)
Stenoses1
- Complications comprised two right-sided and two left-sided pulmonary artery stenoses and one combined left pulmonary arterial and venous obstruction. (northumbria.ac.uk)
Atresia1
- How is unifocalisation used to treat pulmonary atresia? (diaridelsestudiants.com)
Aneurysms3
- Aneurysms of the pulmonary artery are rarely seen in humans or animals. (scielo.cl)
- Aneurysms of the pulmonary artery associated with pulmonary neoplasia have been rarely reported in humans and, to the author's knowledge, have not yet been reported in veterinary medicine. (scielo.cl)
- Peripheral pulmonary artery aneurysms that arise from segmental or intrapulmonary branches are extremely rare, and their management is still controversial. (sumarios.org)
Veins3
- The expansion and contraction is what causes the blood to flow through the heart and to the veins and arteries which are the delivery system of blood to your body. (medbeautys.com)
- The ECMO machine is connected with the veins or arteries of the patient through thick tubes. (janvihospital.com)
- Blood clots most often happen in the veins, instead of the arteries, because blood travels slower than in the arteries. (medlineplus.gov)
Cardiopulmonary bypass3
- Pulmonary artery sling: current results with cardiopulmonary bypass. (medscape.com)
- Endoluminal pulmonary artery banding alone is preferred when controlled pulmonary blood flow and cardiopulmonary bypass are required to address intracardiac abnormalities. (elsevier.com)
- METHODS AND MODELS: Acute ischemic RV dysfunction was induced by progressive embolization of microsphere in the right coronary artery to mimic RV dysfunction clinically experienced during cardiopulmonary bypass separation caused by air microemboli. (bvsalud.org)
Endothelial cells1
- Bovine pulmonary artery endothelial cells (BPAEC) from Cell Applications, Inc. provide an excellent model system to study many aspects of cardiovascular function and disease. (cellapplications.com)
Coronary arteries3
- Most heart attacks are caused by a blood clot that blocks one of the coronary arteries. (stlukes-stl.com)
- The coronary arteries bring blood and oxygen to the heart. (stlukes-stl.com)
- Myocardial ischemia occurs when the blood flow through one or more of your coronary arteries is decreased. (medbeautys.com)
Fetal4
- Double trouble: fetal diagnosis of a pulmonary artery sling and vascular ring. (medscape.com)
- Tretter JT, Tretter EM, Rafii DY, Anderson RH, Bhatla P. Fetal diagnosis of abnormal origin of the left pulmonary artery. (medscape.com)
- Experimental construction of the pulmonary trunk in fetal lambs is accompanied by relatively thin-walled PA resistance vessels. (medscape.com)
- Some researchers postulate this decreased medial muscular layer is caused by a higher oxygen tension of the blood perfusing the fetal pulmonary circulation. (medscape.com)
COPD2
- It is unclear how COPD medications such as inhaled glucocorticoids, phospodiesterase-4 inhibitors, or macrolides, which reduce the risk of exacerbations primarily on the basis of their antiinflammatory properties, would be effective against exacerbations driven by heart disease, thromboembolic disease, or impaired pulmonary reserve," he writes. (medscape.com)
- Smoking is an independent and modifiable risk factor for type 2 diabetes (5), heart disease (6), and chronic obstructive pulmonary disease (COPD) (7). (cdc.gov)
Atrial2
- We present the case of a 3-month-old boy with a large right pulmonary artery to left atrial fistula successfully treated by percutaneous closure. (termedia.pl)
- Based on the echocardiographic examination, the diagnosis of right pulmonary artery to left atrial fistula was made. (termedia.pl)
Hypoxia7
- Zhuan B , Wang X , Wang M , Li Z , Yuan Q , Xie J , Yang Z , . Hypoxia induces pulmonary artery smooth muscle dysfunction through mitochondrial fragmentation-mediated endoplasmic reticulum stress. (aging-us.com)
- PASMC dysfunction accompanied by mitochondrial fragmentation and ER stress was observed in the pulmonary arteries of hypoxia-induced rats with PAH, as well as isolated PASMCs under hypoxia. (aging-us.com)
- These results suggest that hypoxia induces pulmonary artery smooth muscle dysfunction through mitochondrial fragmentation-mediated ER stress and that mitochondrial morphology is a potential target for treatment of hypoxia-induced pulmonary artery smooth muscle dysfunction. (aging-us.com)
- The response of porcine pulmonary arteries to hypoxia depended on their location in the vasculature and the degree and duration of the hypoxic challenge. (elsevier.com)
- The endothelium- dependent relaxation to moderate hypoxia in distal arteries was inhibited only by combined inhibition of endothelium-derived relaxing factor (EDRF)- nitric oxide (NO) synthase [N(ω)-nitro-L-arginine methyl ester (L-NAME)] and cyclooxygenase (indomethacin), suggesting mediation by EDRF-NO and prostacyclin. (elsevier.com)
- Therefore, hypoxia/anoxia may initiate contraction of pulmonary arteries by decreasing the activity of EDRF-NO, but the contractions appear to be maintained by an increased activity of an endothelium-derived contracting factor. (elsevier.com)
- 25. Zhang R, Zhou L, Li Q, Liu J, Yao W, Wan H. Upregulation of two actin- associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia. (bvsalud.org)
Blood11
- Conclusions: Endoluminal pulmonary artery banding provided a consistently effective and durable reduction in pulmonary arterial blood flow with no pulmonary artery distortion. (elsevier.com)
- Pulse is the rhythmic expansion and contraction of an artery caused by the impact of blood pumped by the heart. (cdc.gov)
- As the blood returns to the artery, pulse sounds begin. (cdc.gov)
- Over time, the arteries that supply blood to your heart can become narrow from fatty deposits (plaques). (lynchspharmacy.com)
- In animal studies cinnamon improved blood vessel dilation and blood flow in the coronary artery which supplies blood to the heart. (medbeautys.com)
- Pumping deoxygenated blood into the pulmonary artery. (medbeautys.com)
- Blood flow towards the heart C. Myocardial ischemia can develop slowly as arteries become blocked over time. (medbeautys.com)
- When the heart beats the ventricle pushes blood through the pulmonic valve into the pulmonary artery. (medbeautys.com)
- Angina is not a condition, instead, it is a symptom of coronary artery disease or clogged blood vessels that go to and from the heart. (sesamecare.com)
- Once their it multiples within your pet's pulmonary artery, leading to constricted blood flow, heart disease and major organ failure. (greenlakevet.com)
- However, blood clots in the arteries can also happen. (medlineplus.gov)
Dysfunction2
- Flow variables, distensibility, and WSS are significantly lower compared to healthy controls, and do not show adequate reactions with stress-testing, which is suggestive of pulmonary artery endothelial and/or vascular dysfunction. (eur.nl)
- Early detection of RV dysfunction may be facilitated by continuous monitoring of RV waveform obtained from a pulmonary artery catheter. (bvsalud.org)
Obstruction1
- Anomalous left pulmonary artery causing obstruction to the right main bronchus: report of a case. (medscape.com)
Anomalous Origin2
- We offer care for newborns and children with anomalous origin of the right or left pulmonary artery at Nemours Children's Hospital, Delaware (Wilmington, Del. (nemours.org)
- We offer anomalous origin of the right or left pulmonary artery care at Nemours Children's Health, Pensacola and our hospital affiliate, West Florida Healthcare , with outpatient and follow-up appointments also available at select Nemours locations. (nemours.org)
Surgical2
- Evaluation of left pulmonary artery sling, associated cardiovascular anomalies, and surgical outcomes using cardiovascular computed tomography angiography. (medscape.com)
- Surgical management of pulmonary artery sling in children. (medscape.com)
Heart12
- Other times a pulmonary artery band is placed in an infant born with a hole in their heart. (childrens.com)
- The Pulmonary Artery Reconstruction Program at the Children's Healthcare of Atlanta Heart Center is comprised of a multidisciplinary group of physicians from our cardiothoracic surgery , interventional cardiology, intensive care and anesthesia teams, as well as outpatient cardiologists, pulmonologists , otolaryngologists , geneticists and researchers . (choa.org)
- We are one of only two pediatric heart programs in the United States that offer specialized treatment for children with pulmonary vascular disease and the only such program on the East Coast. (choa.org)
- When Nathan's family was told that his rare heart condition couldn't be treated, the Children's Heart Center's Pulmonary Artery Reconstruction team stepped up with innovative treatments to save his life. (choa.org)
- Watch Dr. Bauser-Heaton explain what makes the Pulmonary Artery Reconstruction Program unique and why it is the right place for your child's heart care. (choa.org)
- This condition can also cause another rare congenital heart defect called pulmonary artery sling . (nemours.org)
- MRI showed marked enlargement of the right heart (ventricle 64.2 mm, atrium 57 mm), pericardial effusion and dissection of the left branch of the pulmonary artery with flap formation. (ersjournals.com)
- Systemic-to-pulmonary artery shunts are amongst the most common palliative procedures performed in neonates with congenital heart defects. (allenpress.com)
- Fragata, JIG 2009, ' Early results of bilateral pulmonary artery banding for hypoplastic left heart syndrome discussion ', European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery , vol. 36, no. 6, pp. 978-979. (unl.pt)
- In most cases, heart problems cause pulmonary oedema. (lynchspharmacy.com)
- To treat the hypertrophic scar, dilate the coronary artery, heal the liver injury and the pulmonary heart disease. (rescuer-gear.com)
- People with asthma, chronic obstructive pulmonary disease, or heart failure may experience worsening of their conditions and have difficulty breathing. (cdc.gov)