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Pulmonary AlveoliLungRiotsPeriodicals as TopicIndiaPeriodicalsPublishingJournal Impact FactorPeriodical Index
Pulmonary Alveoli
Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.
Lung
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Riots
A form of violent crowd behavior which expresses the emotional release of resentments and prejudices, usually relevant to grievances toward the social system.
Periodicals as Topic
A publication issued at stated, more or less regular, intervals.
India
Periodicals
Publishing
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
Journal Impact Factor
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
Periodical Index

Pulmonary capillary perfusion: intra-alveolar fractal patterns and interalveolar independence. (1/4148)

Pulmonary capillary perfusion was analyzed from videomicroscopic recordings to determine flow switching characteristics among capillary segments in isolated, blood-perfused canine lungs. Within each alveolus, the rapid switching pattern was repetitive and was, therefore, nonrandom (fractal dimensions near 1.0). This self-similarity over time was unexpected in a network widely considered to be passive. Among adjacent alveoli, the relationship among the switching patterns was even more surprising, for there was virtually no relationship between the perfusion patterns (coefficients of determination approaching zero). These findings demonstrated that the perfusion patterns in individual alveolar walls were independent of their next-door neighbors. The lack of dependence among neighboring networks suggests an interesting characteristic: the failure of one alveolar-capillary bed would leave its neighbors relatively unaffected, a feature of a robust design.  (+info)

Acinar flow irreversibility caused by perturbations in reversible alveolar wall motion. (2/4148)

Mixing associated with "stretch-and-fold" convective flow patterns has recently been demonstrated to play a potentially important role in aerosol transport and deposition deep in the lung (J. P. Butler and A. Tsuda. J. Appl. Physiol. 83: 800-809, 1997), but the origin of this potent mechanism is not well characterized. In this study we hypothesized that even a small degree of asynchrony in otherwise reversible alveolar wall motion is sufficient to cause flow irreversibility and stretch-and-fold convective mixing. We tested this hypothesis using a large-scale acinar model consisting of a T-shaped junction of three short, straight, square ducts. The model was filled with silicone oil, and alveolar wall motion was simulated by pistons in two of the ducts. The pistons were driven to generate a low-Reynolds-number cyclic flow with a small amount of asynchrony in boundary motion adjusted to match the degree of geometric (as distinguished from pressure-volume) hysteresis found in rabbit lungs (H. Miki, J. P. Butler, R. A. Rogers, and J. Lehr. J. Appl. Physiol. 75: 1630-1636, 1993). Tracer dye was introduced into the system, and its motion was monitored. The results showed that even a slight asynchrony in boundary motion leads to flow irreversibility with complicated swirling tracer patterns. Importantly, the kinematic irreversibility resulted in stretching of the tracer with narrowing of the separation between adjacent tracer lines, and when the cycle-by-cycle narrowing of lateral distance reached the slowly growing diffusion distance of the tracer, mixing abruptly took place. This coupling of evolving convective flow patterns with diffusion is the essence of the stretch-and-fold mechanism. We conclude that even a small degree of boundary asynchrony can give rise to stretch-and-fold convective mixing, thereby leading to transport and deposition of fine and ultrafine aerosol particles deep in the lung.  (+info)

Regulation of an amiloride-sensitive Na+-permeable channel by a beta2-adrenergic agonist, cytosolic Ca2+ and Cl- in fetal rat alveolar epithelium. (3/4148)

1. In cell-attached patches formed on the apical membrane of fetal alveolar epithelium, terbutaline (a specific beta2-adrenergic agonist) increased the open probability (Po) of an amiloride-sensitive Na+-permeable non-selective cation (NSC) channel (control, 0.03 +/- 0.04; terbutaline, 0.62 +/- 0.18; n = 8, P < 0. 00001) by increasing the mean open time 100-fold without any significant change in the mean closed time and without any change in the single channel conductance (control, 27.8 +/- 2.3 pS; terbutaline, 28.2 +/- 2.1 pS; n = 8). 2. The Po of the unstimulated channel increased when the apical membrane was depolarized due to a decrease in the closing rate and an increase in the opening rate, while the Po of the terbutaline-stimulated channel did not depend on the membrane potential. 3. Increased cytosolic [Ca2+] also increased the Po of the channel in a manner consistent with one Ca2+-binding site on the cytosolic surface of the channel. Terbutaline increased the sensitivity of the channel to cytosolic Ca2+ by shifting the concentration of cytosolic Ca2+ ([Ca2+]c) required for half-maximal activation to a lower [Ca2+]c value, leading to an increase in Po. 4. An increase in the cytosolic Cl- concentration ([Cl-]c) decreased the Po of the channel consistent with two Cl--binding sites by increasing the closing rate without any significant change in the opening rate. Terbutaline increased Po by reducing the effect of cytosolic Cl- to promote channel closing. 5. Taken together, these observations indicate that terbutaline activates a Ca2+-activated, Cl--inhibitable, amiloride-sensitive, Na+-permeable NSC channel in fetal rat alveolar epithelium in two ways: first, through an increase in Ca2+ sensitivity, and second, through a reduction in the effect of cytosolic Cl- to promote channel closing.  (+info)

Opportunistic Pneumocystis carinii infection in red-bellied tamarins (Saguinus labiatus). (4/4148)

P. carinii infection in red-bellied tamarins (Saguinus labiatus), born and maintained in a laboratory breeding colony, was examined by histopathologic examination postmortem. P. carinii cysts were detected in 6 of 10 red-bellied tamarins examined, by using Grocott's, toluidine blue O and immunostaining with avidin-biotin complex using antisera for rat-, simian-, and human-P. carinii. The results obtained from the present studies imply that P. carinii may be an important pathogen in this species.  (+info)

Acute saline infusion reduces alveolar-capillary membrane conductance and increases airflow obstruction in patients with left ventricular dysfunction. (5/4148)

BACKGROUND: Impaired alveolar-capillary membrane conductance is the major cause for the reduction in pulmonary diffusing capacity for carbon monoxide (DLCO) in heart failure. Whether this reduction is fixed, reflecting pulmonary microvascular damage, or is variable is unknown. The aim of this study was to assess whether DLCO and its subdivisions, alveolar-capillary membrane conductance (DM) and pulmonary capillary blood volume (Vc), were sensitive to changes in intravascular volume. In addition, we examined the effects of volume loading on airflow rates. METHODS AND RESULTS: Ten patients with left ventricular dysfunction (LVD) and 8 healthy volunteers were studied. DM and Vc were determined by the Roughton and Forster method. The forced expiratory volume in 1 second (FEV1), vital capacity, and peak expiratory flow rates (PEFR) were also recorded. In patients with LVD, infusion of 10 mL. kg-1 body wt of 0.9% saline acutely reduced DM (12.0+/-3.3 versus 10.4+/-3.5 mmol. min-1. kPa-1, P<0.005), FEV1 (2.3+/-0.4 versus 2.1+/-0.4 L, P<0.0005), and PEFR (446+/-55 versus 414+/-56 L. min-1, P<0.005). All pulmonary function tests had returned to baseline values 24 hours later. In normal subjects, saline infusion had no measurable effect on lung function. CONCLUSIONS: Acute intravascular volume expansion impairs alveolar-capillary membrane function and increases airflow obstruction in patients with LVD but not in normal subjects. Thus, the abnormalities of pulmonary diffusion in heart failure, which were believed to be fixed, also have a variable component that could be amenable to therapeutic intervention.  (+info)

TNF-alpha increases ceramide without inducing apoptosis in alveolar type II epithelial cells. (6/4148)

Ceramide is a bioactive lipid mediator that has been observed to induce apoptosis in vitro. The purpose of this study was to determine whether endogenous ceramide, generated in response to in vivo administration of tumor necrosis factor-alpha (TNF-alpha), increases apoptosis in primary rat alveolar type II epithelial cells. Intratracheal instillation of TNF-alpha (5 microgram) produced a decrease in sphingomyelin and activation of a neutral sphingomyelinase. These changes were associated with a significant increase in lung ceramide content. TNF-alpha concomitantly activated the p42/44 extracellular signal-related kinases and induced nuclear factor-kappaB activation in the lung. Hypodiploid nuclei studies revealed that intratracheal TNF-alpha did not increase type II cell apoptosis compared with that in control cells after isolation. A novel observation from separate in vitro studies demonstrated that type II cells undergo a gradual increase in apoptosis after time in culture, a process that was accelerated by exposure of cells to ultraviolet light. However, culture of cells with a cell-permeable ceramide, TNF-alpha, or a related ligand, anti-CD95, did not increase apoptosis above the control level. The results suggest that ceramide resulting from TNF-alpha activation of sphingomyelin hydrolysis might activate the mitogen-activated protein kinase and nuclear factor-kappaB pathways without increasing programmed cell death in type II cells.  (+info)

Pattern of total and regional lung function in subjects with bronchoconstriction induced by 15-me PGF2 alpha. (7/4148)

Closing volume (single breath nitrogen test), regional ventilation and perfusion (using intravenous xenon-133), and total lung function (TLC, VC, and FEV) were measured before and after intramuscular administration of 250 mug 15-methyl prostaglandin F2alpha (15-me PGF2alpha) in 10 healthy women. The cardiac output was measured with the Minnesota impedance cardiograph model 304A and the transthoracic impedance was used as an expression of the thoracic fluid volume. The slope of the alveolar plateau on the closing volume tracing showed a 271% increase 20 minutes after the prostaglandin administration, at which time the closing volume per cent (CV%) had decreased (P less than 0-01) and the closing capacity (CC%) had increased (P less than 0-05). Vital capacity (VC) decreased (P less than 0-01), residual volume (RV) increased (P less than 0-01), and the total lung capacity (TLC) remained unchanged. The maximal decrease (9%) in FEV1 was seen after 20 minutes. All these measurements except the slope of the alveolar plateau returned to control levels after 60 minutes. The redistribution of regional ventilation was more pronounced than that of the regional pulmonary blood flow. No change was observed in cardiac output and transthoracic impedance. None of the patients experienced any dyspnoea. Our results are consistent with a more pronounced effect of prostaglandin F2alpha on the small airways (the alveolar plateau) than on the larger airways (FEV1). In cases where an increase in the slope of the alveolar plateau is observed, the closing volume per cent should not be used as a measurement of the lung disease. It is concluded that the single breath nitrogen test (N2 closing volume) is more sensitive than the conventional tests.  (+info)

Apoptosis is a pathway responsible for the resolution of endotoxin-induced alveolar type II cell hyperplasia in the rat. (8/4148)

Previous studies showed that intratracheal instillation of endotoxin induces transient type II cell hyperplasia in the rat lung and described some of the mechanisms involved in the proliferative response of type II cells. The purpose of the present study was to investigate how long the type II cell hyperplasia persists and how it is resolved. The portion of epithelial cells in hyperplastic lesions of the rat lung expressing cyclin D1, an indicator for cells in the G1 phase of the cell cycle, was greatest at 3 d post instillation and decreased after 4 and 6 d. The fate of the proliferating epithelial cells was traced by injecting the rats with 5-bromo-2' deoxy uridine (BrdU) 2 d post instillation, the peak time point for maximum incorporation of BrdU. Exfoliated BrdU-positive epithelial cells were detected in the alveolar spaces in tissue sections from rats 4, 5, and 6 d post instillation. BrdU-positive epithelial cells showed flattened nuclei at 6 and 10 d post instillation. Expression of the 116 kD poly(ADP-ribose) polymerase (PARP) was low in type II cells from control rats, and was increased at 3, 4, and 6 d post instillation. In cells obtained by lavage, only a 35 kD cleavage product of PARP was detected, which is an indicator of necrotic cell death. In isolated type II cells from rats 3, 4, and 6 d post endotoxin instillation, progressive cleavage of the PARP to its 89 kD residual fragment was detected, which is a direct evidence for the activation of caspases. Furthermore, apoptotic epithelial cells with condensed nuclei were identified by electron microscopy in rats 4 d post instillation. These results indicate that apoptosis is an additional mechanism for the resolution of endotoxin-induced lung epithelial hyperplasias.  (+info)

Altered proteomic patterns in rat alveolar epithelial type II cells after ventilation with high and low tidal volumes |...Altered proteomic patterns in rat alveolar epithelial type II cells after ventilation with high and low tidal volumes |...
A proteomics approach to ventilator-induced lung injury might identify protein patterns that contribute to epithelial injury. To identify changes in alveolar type II cells (ATII), rats were mechanically ventilated for 5 hours with a high tidal volume (HTV; 20 ml/kg, no positive end expiratory pressure) or a low tidal volume (LTV; 6 ml/kg, positive end expiratory pressure 4 cmH2O) and compared with pooled controls without mechanical ventilation (SV). ATII were isolated and lysed. Protein expression was compared using the recently introduced cleavable isotope coded affinity tag (ICAT) methodology. After tryptic digestion, cysteine containing peptides were tagged with biotin, extracted using an avidin-coated column and identified by HPLC and mass spectrometry with collision-induced dissociation. Spectra were interrogated against the Swissprot database and quantified using the ProteinProspector software. HTV ventilation resulted in morphologic changes, pulmonary edema and neutrophil influx in the ...
https://rd.springer.com/article/10.1186/cc2491
Vacuolar ATPase Regulates Surfactant Secretion in Rat Alveolar Type II Cells by Modulating Lamellar Body CalciumVacuolar ATPase Regulates Surfactant Secretion in Rat Alveolar Type II Cells by Modulating Lamellar Body Calcium
Lung surfactant reduces surface tension and maintains the stability of alveoli. How surfactant is released from alveolar epithelial type II cells is not fully understood. Vacuolar ATPase (V-ATPase) is the enzyme responsible for pumping H+ into lamellar bodies and is required for the processing of surfactant proteins and the packaging of surfactant lipids. However, its role in lung surfactant secretion is unknown. Proteomic analysis revealed that vacuolar ATPase (V-ATPase) dominated the alveolar type II cell lipid raft proteome. Western blotting confirmed the association of V-ATPase a1 and B1/2 subunits with lipid rafts and their enrichment in lamellar bodies. The dissipation of lamellar body pH gradient by Bafilomycin A1 (Baf A1), an inhibitor of V-ATPase, increased surfactant secretion. Baf A1-stimulated secretion was blocked by the intracellular Ca2+ chelator, BAPTA-AM, the protein kinase C (PKC) inhibitor, staurosporine, and the Ca2+/calmodulin-dependent protein kinase II (CaMKII), KN-62. Baf A1
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009228
State-dependent inactivation of K+ currents in rat type II alveolar epithelial cells. | JGPState-dependent inactivation of K+ currents in rat type II alveolar epithelial cells. | JGP
Inactivation of K+ channels responsible for delayed rectification in rat type II alveolar epithelial cells was studied in Ringer, 160 mM K-Ringer, and 20 mM Ca-Ringer. Inactivation is slower and less complete when the extracellular K+ concentration is increased from 4.5 to 160 mM. Inactivation is faster and more complete when the extracellular Ca2+ concentration is increased from 2 to 20 mM. Several observations suggest that inactivation is state-dependent. In each of these solutions depolarization to potentials near threshold results in slow and partial inactivation, whereas depolarization to potentials at which the K+ conductance, gK, is fully activated results in maximal inactivation, suggesting that open channels inactivate more readily than closed channels. The time constant of current inactivation during depolarizing pulses is clearly voltage-dependent only at potentials where activation is incomplete, a result consistent with coupling of inactivation to activation. Additional evidence for ...
http://jgp.rupress.org/content/95/4/617
Role of MRCKa and Na+,K+-ATPase signaling in alveolar barrier function in the mouse lung - American Heart Association Research...
Acute Respiratory Distress Syndrome (ARDS) is a severe medical condition which is characterized by significant alveolar fluid accumulation and insufficient gas exchange. Cardiac surgery, ECMO, and use of cardiac medications are all known risk factors for ARDS which also complicates management of these and other cardiovascular diseases. Effective alveolar fluid clearance and repair of a functional alveolar-capillary barrier are considered the primary mechanisms for edema resolution in ARDS. Apart from enhancing fluid clearance, the Na+,K+-ATPase has been shown important for alveolar barrier function. Our lab showed that overexpression of the Na+,K+-ATPase b1 subunit into lungs enhances alveolar barrier integrity in previously injured lungs in mice and pigs. Previous in vitro data indicated that MRCKa mediates the upregulation of tight junction (TJ) proteins and epithelial barrier integrity by b1 overexpression. I hypothesize that the b1-Na+,K+-ATPase regulates alveolar barrier function through ...
https://pureresearch.americanheart.org/en/awards/role-of-mrcka-and-nakatpase-signaling-in-alveolar-barrier-function-in-the-mouse-lung
Epithelial stem/progenitor cells as repair agents in diffuse alveolar damage | Global Research ProjectsEpithelial stem/progenitor cells as repair agents in diffuse alveolar damage | Global Research Projects
The overall goal of this application is to develop a compelling rationale and workable methodology for the treatment of diffuse alveolar damage with transplanted human epithelial stem/progenitor cells capable of long term engraftment and improved organ function. Stem/progenitor replacement therapy is envisioned as a meaningful therapeutic adjunct in several clinical situations dominated by diffuse alveolar damage with epithelial loss: severe, acute lung injury, e.g. due to influenza or other causes of ARDS, as well as acute exacerbations of chronic fibrotic lung disease. Recent studies discussed in the application indicate effective alveolar regeneration, and thus improved lung function, requires both a first phase of expansion and migration of stem/progenitor cells to re-establish alveolar barriers followed by a second phase of differentiation of new barrier cells into mature type II (AEC2s) and type I alveolar cells. To develop a translational program for alveolar regeneration by ...
http://globalprojects.ucsf.edu/project/epithelial-stemprogenitor-cells-repair-agents-diffuse-alveolar-damage
Gereke, M., Jung, S., Buer, J. and Bruder, D. (2009) Alveolar type II epithelial cells present antigen to CD4(1) T cells and...Gereke, M., Jung, S., Buer, J. and Bruder, D. (2009) Alveolar type II epithelial cells present antigen to CD4(1) T cells and...
Gereke, M., Jung, S., Buer, J. and Bruder, D. (2009) Alveolar type II epithelial cells present antigen to CD4(1) T cells and induce Foxp3(1) regula-tory T cells. American Journal of Respiratory and Critical Care Medicine, 179, 344-355. doi10.1164/rccm.200804-592OC
http://www.scirp.org/reference/ReferencesPapers.aspx?ReferenceID=730672
JCI - Yap/Taz regulate alveolar regeneration and resolution of lung inflammationJCI - Yap/Taz regulate alveolar regeneration and resolution of lung inflammation
Alveolar epithelium plays a pivotal role in protecting the lungs from inhaled infectious agents. Therefore, the regenerative capacity of the alveolar epithelium is critical for recovery from these insults in order to rebuild the epithelial barrier and restore pulmonary functions. Here, we show that sublethal infection of mice with Streptococcus pneumoniae, the most common pathogen of community-acquired pneumonia, led to exclusive damage in lung alveoli, followed by alveolar epithelial regeneration and resolution of lung inflammation. We show that surfactant protein C-expressing (SPC-expressing) alveolar epithelial type II cells (AECIIs) underwent proliferation and differentiation after infection, which contributed to the newly formed alveolar epithelium. This increase in AECII activities was correlated with increased nuclear expression of Yap and Taz, the mediators of the Hippo pathway. Mice that lacked Yap/Taz in AECIIs exhibited prolonged inflammatory responses in the lung and were delayed in ...
https://www.jci.org/articles/view/125014/pdf
The fibroblast of human lung alveolar structures: a differentiated cell with a major role in lung structure and function.
The fibroblast of human lung alveolar structures: a differentiated cell with a major role in lung structure and function. Review ...
http://vivo.med.cornell.edu/display/pubid0018884481
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Notch is an ancient cell-signaling system that regulates the specification of cell fate. Recently, Notch was found to confer antigen presenting cell function on mast cells, induce histamine release in human basophils and regulate migration and survival of eosinophils.. In acute lung injury, alveolar type II cells activate macrophages, secrete soluble mediators, migrate and spread in response to the injury. Additionally, Notch stimulated myofibroblast differentiation and migration of cultured RLE-6TN cells. However, until now, nothing is known on the role of Notch activation regarding proliferation of rat alveolar type II cells.. Rat alveolar type II cells (RLE 6TN) were obtained from the American Type Culture Collection (ATCC no. CRL-2300; Manassas, VA, USA) and were cultured in DMEM/Hams F12 containing 10% fetal calf serum and L-glutamine. Cell proliferation was measured by direct cell count and the fluorometric proliferation assay EZ4U basing on tetrazolium salt reduction. Cells were ...
http://erj.ersjournals.com/content/40/Suppl_56/P3759
Development of a lung model utilizing human alveolar epithelial cells for evaluating aerosol drug delivery | RTIDevelopment of a lung model utilizing human alveolar epithelial cells for evaluating aerosol drug delivery | RTI
Kazantseva, M., Cooney, D., & Hickey, A. (2002). Development of a lung model utilizing human alveolar epithelial cells for evaluating aerosol drug delivery. In Respiratory Drug Delivery VIII (pp. 707 - 710). Raleigh, NC: Davis Horwood International Publishing, Ltd ...
https://www.rti.org/publication/development-lung-model-utilizing-human-alveolar-epithelial-cells-evaluating-aerosol-drug
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The present study was undertaken to explore at the cellular level possible mechanisms of KGF action susceptible to account for its protective effects toward the exposure of the developing lung to hyperoxia, used as a model of alveolar injury. We report an enhanced rate of alveolar cell wound closure in vitro and maintenance of lung cell content in vivo, likely due to enhanced survival of alveolar epithelial type II cells.. Most studies demonstrating a protective effect of KGF against lung injury have used the intratracheal route (38, 54), rather than the systemic route (6), whereas we administered KGF intraperitoneally and during oxygen exposure. Possible mechanisms to explain the protective effects of KGF in acute lung injury were recently reviewed (57) and are mainly based on effects on alveolar and airway epithelial cells, including increased proliferation (33, 39, 53, 63), increased surfactant production (14, 27, 50, 61), enhanced DNA repair (12, 51, 60), and decreased apoptosis (12, 43). ...
http://ajplung.physiology.org/content/297/5/L965
Involvement of an NAD(P)H oxidase-like enzyme in superoxide anion and hydrogen peroxide generation by rat type II cells. |...Involvement of an NAD(P)H oxidase-like enzyme in superoxide anion and hydrogen peroxide generation by rat type II cells. |...
BACKGROUND: Although alveolar macrophages are considered to be the primary cellular mediators of host defence in the lung, there is increasing evidence that type II cells may also play an active role in host defence. A study was undertaken to investigate whether type II cells generate O2-. and H2O2 via an NADPH oxidase-like system and whether exposure of the type II cells to soluble or particulate stimuli known to activate NADPH oxidase in macrophages also leads to increased production of H2O2. METHODS: Rat type II cells and alveolar macrophages were exposed to 10, 100, or 1000 nM phorbol-12-myristate-13-acetate (PMA) and the production of O2-. and H2O2 was determined by chemiluminescence. Thirty minutes before stimulation with 1 microM PMA type II cells were also exposed to the same concentrations of a protein kinase C (PKC) antagonist GF109203x, the non-selective protein kinase inhibitor staurosporine (1, 10, or 100 nM), or the NADPH oxidase inhibitor diphenyliodonium chloride (DPI) (1, 10, ...
https://thorax.bmj.com/content/52/5/465
Endothelial responses of the alveolar barrier in vitro in a dose-controlled exposure to diesel exhaust particulate matter |...Endothelial responses of the alveolar barrier in vitro in a dose-controlled exposure to diesel exhaust particulate matter |...
During the last 250 years, the level of exposure to combustion-derived particles raised dramatically in western countries, leading to increased particle loads in the ambient air. Among the environmental particles, diesel exhaust particulate matter (DEPM) plays a special role because of its omnipresence and reported effects on human health. During recent years, a possible link between air pollution and the progression of atherosclerosis is recognized. A central effect of DEPM is their impact on the endothelium, especially of the alveolar barrier. In the present study, a complex 3D tetraculture model of the alveolar barrier was used in a dose-controlled exposure scenario with realistic doses of DEPM to study the response of endothelial cells. Tetracultures were exposed to different doses of DEPM (SRM2975) at the air-liquid-interface. DEPM exposure did not lead to the mRNA expression of relevant markers for endothelial inflammation such as ICAM-1 or E-selectin. In addition, we observed neither a
https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/s12989-017-0186-4
Searching for pulmonary alveoliSearching for pulmonary alveoli
The Orthopedics PERL Channel contains hundreds of items, including full-color medical illustrations, medical animations and patient education articles. The Orthopedics Channel covers topics relevant to skeletal and muscular anatomy, orthopedic injury and repair, and general sports medicine. Health Animation channels are produced by Nucleus Medical Media, Inc.
http://prenateperl.com/search?q=pulmonary%20alveoli
overexpanded pulmonary alveoli Mammalian Phenotype Term (MP:0001183)overexpanded pulmonary alveoli Mammalian Phenotype Term (MP:0001183)
The Mammalian Phenotype (MP) Ontology is a community effort to provide standard terms for annotating phenotypic data. You can use this browser to view terms, definitions, and term relationships in a hierarchical display. Links to summary annotated phenotype data at MGI are provided in Term Detail reports.
http://www.informatics.jax.org/vocab/mp_ontology/MP:0001183
In vitro effects induced by diesel exhaust at an air-liquid interface in a human lung alveolar carcinoma cell line A549. |...
PubMedID: 25983017 | In vitro effects induced by diesel exhaust at an air-liquid interface in a human lung alveolar carcinoma cell line A549. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie | 7/19/2015
https://www.docphin.com/research/article-detail/17208826/PubMedID-25983017/In-vitro-effects-induced-by-diesel-exhaust-at-an-air-liquid-interface-in-a-human-lung-alveolar-carcinoma-cell-line-A549
Rapid isolation of type II pneumocytes with magnetic removal of macrophagesRapid isolation of type II pneumocytes with magnetic removal of macrophages
A method is described for the rapid preparation of lung cell fractions enriched in type II alveolar pneumocytes. Isolated perfused rabbit lungs are exposed to Fe3O4 by tracheal lavage, which permits pulmonary alveolar macrophages to phagocytize the particles. Alveolar epithelial cells are then selectively freed from the basement membrane matrix by critical placement of collagenase and elastase. Detached cells are harvested either by repeated tracheal lavage or by mincing the lobes and filtering freed cells through a series of nylon mesh sieves. Iron oxide-containing macrophages are then removed from the harvested cells by a strong magnetic field. A final sizing of the macrophage-depleted suspension yields a preparation enriched in alveolar type II cells. Eight million viable cells (95% type II) were obtained per rabbit lung when harvested by lavage, while 32 ± 106 (88% type II) cells were obtained from minced lungs. These values for cell yield and relative purity are comparable to previously ...
https://scholars.uab.edu/display/pub1097279
Frontiers | Regulation of Lung Epithelial Sodium Channels by Cytokines and Chemokines | ImmunologyFrontiers | Regulation of Lung Epithelial Sodium Channels by Cytokines and Chemokines | Immunology
Acute lung injury (ALI) leading to acute respiratory distress (ARDS) is a global health concern. ARDS patients have significant pulmonary inflammation leading to flooding of the pulmonary alveoli. This prevents normal gas exchange with consequent hypoxemia, and causes mortality. A thin fluid layer in the alveoli is normal. The maintenance of this thin layer results from fluid movement out of the pulmonary capillaries into the alveolar interstitium driven by vascular hydrostatic pressure and then through alveolar tight junctions. This is then balanced by fluid reabsorption from the alveolar space mediated by transepithelial salt and water transport through alveolar cells. Reabsorption is a two-step process: first, sodium enters via sodium-permeable channels in the apical membranes of alveolar type 1 and 2 cells followed by active extrusion of sodium into the interstitium by the basolateral Na+, K+-ATPase. Anions follow the cationic charge gradient and water follows the salt-induced osmotic
https://www.frontiersin.org/articles/10.3389/fimmu.2017.00766/full
Correction of Genetic Mutation in Stem Cells Offers Directions for Treatment of Lung Diseases in Children | School of Medicine
For the first time, researchers have developed a way to coax pluripotent stem cells into a specific type of mature lung cell called alveolar epithelial type II cells (AEC2s) and to correct a mutant gene whose dysfunction in these cells is known to cause respiratory distress in infants.. The findings, which appear in Cell Stem Cell, will make it easier to study lung diseases like neonatal respiratory distress, COPD and interstitial lung diseases, caused by dysfunctional AEC2s, which until now were unable to survive and multiply long enough in cell culture to be studied or genetically corrected.. AEC2s are the key cells that act to maintain lung air sacs in both infants and adults. They are responsible for responding to lung injury and secreting a substance called pulmonary surfactant that helps keep the lungs open. It is believed that dysfunction of these specific cells leads to the development of many poorly understood alveolar lung diseases (diseases of the air sacs in the lungs) and is the ...
http://www.bumc.bu.edu/busm/2017/09/28/correction-of-genetic-mutation-in-stem-cells-offers-directions-for-treatment-of-lung-diseases-in-children/
Ceramide membrane microdomains regulate cytokine secretion - Brij SinghCeramide membrane microdomains regulate cytokine secretion - Brij Singh
Although alveolar epithelial type II cells (AECII) form the barrier of alveolar spaces and produce surfactants to maintain lung integrity, the unique AECII popu...
http://grantome.com/grant/NIH/R03-AI097532-02
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Hepatocyte growth factor (HGF) is a cytokine with pleiotropic functions during wound healing and repair. Its anti-fibrotic effects were shown in animal models of lung fibrosis and linked to improved cellular survival and proliferation and reduced myofibroblast accumulation. HGF-elicited, pro-survival pathways have yet not been investigated in detail in lung epithelial cells. Based on literature, our study is focused on Bcl-xL, prosurvival protein involved in mitochondrial control of apoptosis.. Results: Western blot analysis of IPF lung homogenates revealed significantly increased expression of Bcl-xL when compared to donor lungs, and a similar observation was made in bleomycin versus saline treated murine lungs. In human IPF, much less in donor lungs, Bcl-xL protein is highly expressed in hyperplastic alveolar epithelial type II cells, basal cells, bronchial epithelial ciliated and non-ciliated cells. Furthermore, Bcl-xL expression co-localized with specific HGF receptor cMet. In vitro data ...
http://erj.ersjournals.com/content/42/Suppl_57/3523
Acute Lung Injury
Type I cells are eroded from inflamed, edematous alveolar walls with scattered PMNs. Proteinaceous exudate (the hyaline membrane) lines respiratory bronchioles, alveolar ducts (arrow), and some alveoli. Type II cell hyperplasia indicates early repair.. Organizing diffuse alveolar damage ...
http://pathhsw5m54.ucsf.edu/overview/acuteli.html
JCI - Influenza leaves a TRAIL to pulmonary edemaJCI - Influenza leaves a TRAIL to pulmonary edema
Peteranderl and colleagues define a paracrine communication between macrophages and type II alveolar epithelial cells during influenza infection where IFNα induces macrophage secretion of TRAIL that causes endocytosis of Na,K-ATPase by the alveolar epithelium. This reduction of Na,K-ATPase expression decreases alveolar fluid clearance, which in turn leads to pulmonary edema. Inhibition of the TRAIL signaling pathway has been shown to improve lung injury after influenza infection, and future studies will be needed to determine if blocking this pathway is a viable option in the treatment of ARDS.. ...
https://www.jci.org/articles/view/86802/figure/1
Alterations in gene expression and DNA methylation during murine and human lung alveolar septation. - PubMed - NCBIAlterations in gene expression and DNA methylation during murine and human lung alveolar septation. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/25387348?dopt=Abstract
Alveolar tissue inflammation in asthma - ePrints SotonAlveolar tissue inflammation in asthma - ePrints Soton
As physiologic and autopsy evidence suggests that peripheral airways and parenchyma are involved in asthma, we hypothesized that significant alveolar tissue inflammation is present in patients with stable, chronic asthma. Eleven patients with nocturnal asthma (NA) and 10 patients with non-nocturnal asthma (NNA) were studied. Each subject underwent two bronchoscopies with proximal airway endobronchial and distal alveolar tissue transbronchial biopsy in a random order at 4:00 P.M. and 4:00 A.M. Morphometric analysis was used to determine the number per volume (Nv) of inflammatory cells. Between-group comparisons showed that the Nv of eosinophils was greater in the NA alveolar tissue 4:00 A.M. compared with the subjects with NNA (40.2 x 10(3) [26.4-57.1 x 10(3), IQ] versus 15.7 x 10(3) [2.1-35.2 x 10(3), IQ], p = 0.05). In regard to the airway biopsies, no difference in the inflammatory and epithelial cells between the two groups was seen at either time. The NA group exhibited greater eosinophils ...
https://eprints.soton.ac.uk/191011/
A cell culture model for alveolar epithelial transport [PeerJ Preprints]A cell culture model for alveolar epithelial transport [PeerJ Preprints]
Background: The thickness and composition of the surface liquid lining the human lungs are maintained by a balance between epithelial secretion and absorption of ions and water. An understanding of epithelial transport pathways and the factors that regulate them will provide insight into the development of conditions such as lung edema and guide the development of treatment modalities. Here we report on the development and characterisation of a cell culture model of the alveolar epithelium that will be useful for investigating the components of epithelial transport pathways and interpreting molecular mechanisms involved in transport related diseases. Methods: An in vitro cell culture model was developed using human alveolar epithelial cell lines NCI-H441 and A549 cultured with the apical surface exposed to air (air-medium) or covered by nutrient medium (medium-medium). Cell monolayer was presented by visualizing cell morphology under microscope. Transepithelial electrical resistance, potential
https://peerj.com/preprints/256/
Epithelium Ultrastructure | LONG HAIRSTYLESEpithelium Ultrastructure | LONG HAIRSTYLES
Lung cell biology - comprehensive physiology, The sections in this article are: 1 basic plan of the cell1. Pulmonary alveolus - wikipedia, An alveolus (plural: alveoli, from latin alveolus, little cavity) is a hollow cavity found in the lung parenchyma, and is the basic unit of ventilation .. Are all different types of barretts epithelium originally, Are all different types of barretts epithelium originally present, or do they appear only after some period of evolution? d. parekh, g.w.b. clark, t.r. demeester. ...
http://www.longhairpicture.net/epithelium/epithelium-ultrastructure.html
Alveolar Epithelial Cells Are Critical in Protection of the Respiratory Tract by Secretion of Factors Able To Modulate the...Alveolar Epithelial Cells Are Critical in Protection of the Respiratory Tract by Secretion of Factors Able To Modulate the...
Our working hypothesis has been that AEC-derived factors are important in providing micro environmental signals that are able to modify the functional behavior of incoming and tissue-resident cells, thus contributing to the homeostasis and defensive mechanisms of the respiratory tract. We chose to work preferentially with interstitial pulmonary macrophages (PuM) instead of alveolar macrophages (AM) because PuM are important in the defense against microbial aggressions and also because they are in close contact with other immune cells in the lung interstitium. We have used for their purification an established methodology considered to result in high-purity interstitial macrophages (23-25), while high-purity AM are most frequently prepared from the bronchoalveolar lavage (23-25). However, even if it is possible that a minor fraction of AM could be present in our preparations (35), we are confident that the results presented here are compatible with the functionality of PuM. Among other aspects, ...
https://iai.asm.org/content/81/1/381
Browsing Publications of the RG Phagosomen Biologie by Subject (MeSH)Browsing Publications of the RG Phagosomen Biologie by Subject (MeSH)
Bacterial and parasitic intracellular pathogens or their secreted products have been shown to induce host cell transcriptional responses, which may benefit the host, favour the microorganism or be unrelated to the infection. In most instances, however, it is not known if the host cell nucleus is proximately required for the development of an intracellular infection. This information can be obtained by the infection of artificially enucleated host cells (cytoplasts). This model, although rather extensively used in studies of viral infection, has only been applied to few bacterial pathogens, which do not include Mycobacterium spp. Here, we investigate the internalization, phagosome biogenesis and survival of M. smegmatis in enucleated type II alveolar epithelial cells. Cytoplasts were infected with M. smegmatis, but the percentage of infection was significantly lower than that of nucleated cells. Scanning electron microscopy indicated that in both cells and cytoplasts, bacteria were internalized ...
https://repository.helmholtz-hzi.de/handle/10033/116410/browse?type=mesh&value=Microscopy%2C+Electron
Tackling tuberculosis with a model cow lung | University of SurreyTackling tuberculosis with a model cow lung | University of Surrey
Bovine tuberculosis (BTB) is a zoonosis which infects livestock and wildlife. While BTB has been largely eliminated from many countries, the control of Mycobacterium bovis (the bacteria that causes BTB) has proved problematic in large parts of Great Britain. If control doesnt improve, the projected economic burden of the disease could reach £1 billion in the next decade.. Surrey researchers have won NC3Rs funding to produce an in vitro tissue culture model of the cow lung, with an air-liquid interface that recreates the fundamental elements of the bovine pulmonary alveolus (the small air spaces in the lungs where carbon dioxide leaves the blood and oxygen enters it).. The model will allow the team to study what happens when a bovine lung is infected with virulent mycobacteria. Through collaboration with the bovine TB research group at the Animal & Plant Health Agency, the model will be used to test whether successful vaccines exert their effect at the very earliest stages of infection, when ...
https://www.surrey.ac.uk/mediacentre/features/tackling-tuberculosis-model-cow-lung
Lipoarabinomannan (LAM) is a lipid virulence element secreted by (Mtb) the | BACE1 Inhibitors for the Treatment of Alzheimers...Lipoarabinomannan (LAM) is a lipid virulence element secreted by (Mtb) the | BACE1 Inhibitors for the Treatment of Alzheimers...
Lipoarabinomannan (LAM) is a lipid virulence element secreted by (Mtb) the etiologic agent of tuberculosis. features markers TLR2+ and TLR4+ macrophages decreased KX2-391 however the percentage of MMR+ manifestation didnt modification also. LAM-exposed monocytes produced Rabbit polyclonal to Junctophilin-2 macrophages KX2-391 which were much less efficient in creating proinflammatory cytokines such as for example TNF-and IFN-Mycobacterium tuberculosis(Mtb) the causal agent of TB can be sent through inhalation of aerosolized droplets that access the pulmonary alveoli. Once there the bacterias bind different phagocytic receptors and enter citizen alveolar macrophages dendritic cells and recruited monocytes through the bloodstream thus creating a mobile structure known as granuloma [2]. Mtb can be an intracellular pathogen whose cell wall structure framework makes up about its low level of resistance and permeability to antibiotics. Its primary structural parts are lipids sugars and a part of ...
https://scienceonstageturkey.com/lipoarabinomannan-lam-is-a-lipid-virulence-element-secreted-by-mtb-the/
cancer health center: November 2009cancer health center: November 2009
The main function of the lungs is gas exchange between blood and the air we breathe. The work of the lungs, carbon dioxide is removed from the blood and the inspired oxygen enters the bloodstream. Right lung has three lobes, whereas left lung is divided into two lobes and a smaller structure called the lingula which is equivalent to the middle lobe. Major airways into the lungs are the bronchi, resulting in the trachea. Bronchi branch into progressively smaller airways called bronchiole. They end in small bags known as pulmonary alveoli. The wafers are exchanged gas itself. Lungs and chest wall are covered with a thin layer of tissue called pleura ...
http://cancersymptoms.blogspot.com/2009/11/?widgetType=BlogArchive&widgetId=BlogArchive1&action=toggle&dir=open&toggle=MONTHLY-1222844400000&toggleopen=MONTHLY-1257058800000
Microscopic Study of the Lungs of Sprague-Dawley Rats from Various Ages of Postnatal and Aging Periods | Science PublicationsMicroscopic Study of the Lungs of Sprague-Dawley Rats from Various Ages of Postnatal and Aging Periods | Science Publications
Physiological changes in postnatal and aging lung are associated with a variety of microscopic changes in the lung, especially the alveolar lung tissue, both in the interstitial and epithelial component. Interstitial tissue of the lung will increase in thickness that is supposed to be due to changes in fiber composition, particularly collagen. However, the exact changes are still under debate and the underlying process is still unclear. The epithelial component that experiences changes is type II alveolar cells or pneumocyte II (surfactant producing cells). The ratio of pneumocyte II against pneumocyte I is expected to decline with age. This decrease will certainly affect their function in maintaining pulmonary surfactant supply. To maintain normal vital functions and synthesis of surfactant, lung tissue is also dependent on the availability of glucose because glucose is the fundamental building blocks of glycerol backbone of surfactant. In the aging process, accumulation of glycogen in the brain,
http://thescipub.com/abstract/10.3844/ojbsci.2015.74.82
Blood Oxygenation - Membrana GmbH Solutions for Healthcare and Industrial FilrationBlood Oxygenation - Membrana GmbH Solutions for Healthcare and Industrial Filration
An oxygenator or artificial lung adds oxygen to the patients blood and removes carbon dioxide.. In open heart surgery, a heart-lung-machine is used for temporary replacement of the functions of both the heart and the lungs. This is necessary to enable the surgeon to perform the complicated surgical procedure in a motionless field. Both heart and lungs are rested during surgery. The oxygenator with membranes inside is the main element in the heart-lung-machine, responsible for gas exchange.. In intensive care and interventional pneumology, innovative artifical lungs provide extracorporeal removal of carbon dioxide and oxygen enrichment of the blood. This gives the human lungs time to heal. Similar to heart surgery, special membranes in the membrane ventilator assume the fuction of the pulmonary alveoli.. In both applications, a heat exchanger is often used. As large volumes of blood are channeled outside the patients body, temperature fluctuations may easily occur. The heat exchanger allows ...
http://membrana.com/healthcare/applications/blood-oxygenation
Essay about Four Basic Tissue Types and Their Function - 713 WordsEssay about Four Basic Tissue Types and Their Function - 713 Words
There are four different types of tissue. They are; nerve, epithelial, connective, and muscle. The nerve tissue is made up of neurons that receive and transmit electrical impulses, this is their function. There are several different types of epithelial tissue. First there is simple squamous epithelium tissue. This is a single layer of cells that is in the lining of blood vessels, the lining of the pulmonary alveoli, and the Bowmans capsule in the kidneys. The function of this tissue is to separate blood from the fluid in tissues and to separate air from fluids in tissues and to filter substances from blood to form urine. The next type of epithelial tissue is stratified squamous epithelium. This is a tissue composed of two or more layers and the cells tend to be cuboidal. This type of tissue is found in the epidermis of the skin and the linings of the mouth, pharynx, esophagus and anus. The function of this tissue is to protect and secrete. Transitional epithelium is the next type of tissue and ...
http://www.studymode.com/essays/Four-Basic-Tissue-Types-And-Their-1278444.html
Normal Lung Alveoli And Surrounding Capillaries The Sites Of Gas Exchange Lm Stockfoto | Getty ImagesNormal Lung Alveoli And Surrounding Capillaries The Sites Of Gas Exchange Lm Stockfoto | Getty Images
Bekijk Stockfoto van Normal Lung Alveoli And Surrounding Capillaries The Sites Of Gas Exchange Lm. Ga voor hoogwaardige fotos met een hoge resolutie naar Getty Images.
https://www.gettyimages.be/detail/foto/normal-lung-alveoli-and-surrounding-capillaries-the-sites-stockfotos/vis69204
Normal Lung Alveoli And Surrounding Capillaries The Sites Of Gas Exchange Lm Foto stock | Getty ImagesNormal Lung Alveoli And Surrounding Capillaries The Sites Of Gas Exchange Lm Foto stock | Getty Images
Guarda Foto stock di Normal Lung Alveoli And Surrounding Capillaries The Sites Of Gas Exchange Lm. Cerca foto premium ad alta risoluzione su Getty Images.
https://www.gettyimages.it/detail/foto/normal-lung-alveoli-and-surrounding-capillaries-the-fotografie-stock/vis69204
Jennifer L. Young, Ph.D. - University of Rochester Medical CenterJennifer L. Young, Ph.D. - University of Rochester Medical Center
My research focuses on elucidating the mechanism(s) of cell death and survival of primary alveolar epithelial cells and lung fibroblasts in response to the extracellular matrix associated signaling molecule, CCN1/Cyr61. CCN1/Cyr61 is an extracellular matrix (ECM)-associated signaling molecule that functions to promote cell adhesion, migration, survival and differentiation in the context of vascular development. Most recently we have shown that CCN1/Cyr61 can also modulate cell death in certain cells and can promote cell death in response to TNFa. In the context of the lung, I have found that CCN1/Cyr61 together with TNFa causes apoptosis of alveolar epithelial cells and lung fibroblasts. Because CCN1/Cyr61 has been shown to be induced in the lungs of patients with COPD and ARDS, I hypothesize that CCN1/Cyr61, together with inflammatory mediators such as TNFa causes cell death of primary lung cells in vivo, thus contributing to lung injury. I have also found that CCN1/Cyr61 functional knock-out ...
https://www.urmc.rochester.edu/people/27111512-jennifer-l-young
THE USE OF TRANSALVEOLAR SUTURESTHE USE OF TRANSALVEOLAR SUTURES
Just this morning we performed a surgery where we rebuilt the dental ridge and used Transalveolar Suturing to help preserve the attached gum tissue around our dental implant sites. I first saw this presented at the Pikos Institute bone grafting course a number of years ago and we have used it ever since. The idea…
https://www.jaw-doc.com/blog/transalveolar-sutures/
KAKEN - Research Projects | Alveolar macrophage-derived chemotactic factor for airway epithelial cells (KAKENHI-PROJECT...KAKEN - Research Projects | Alveolar macrophage-derived chemotactic factor for airway epithelial cells (KAKENHI-PROJECT...
Principal Investigator：SHOJI Shunsuke, Project Period (FY)：1993 - 1995, Research Category：Grant-in-Aid for General Scientific Research (C), Research Field：Respiratory organ internal medicine
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05670519/
MyJournals.org - Science - Displacement in root apex and changes in incisor inclination affect alveolar bone remodeling in...MyJournals.org - Science - Displacement in root apex and changes in incisor inclination affect alveolar bone remodeling in...
MyJournals.org - Science - Displacement in root apex and changes in incisor inclination affect alveolar bone remodeling in adult bimaxillary protrusion patients: a retrospective study (Head & Face Medicine)
https://www.myjournals.org/index.php?nr=609692
COVID-19: Pathophysiology - Merck Manuals Professional EditionCOVID-19: Pathophysiology - Merck Manuals Professional Edition
SARS-CoV-2 Host Cell Receptor. The surface of SARS-CoV-2 virus is covered by a large number of spike proteins, which are essential for the virus to gain entry into host cells. Each spike protein consists of two subunits, S1 and S2. The S1 subunit at the tip of the spike contains the receptor-binding domain (RBD) that binds to angiotensin-converting enzyme 2 (ACE2), the host cell receptor, while the S2 subunit, located on the stalk of the spike, mediates virus-host cell membrane fusion that is necessary for viral entry (1). For membrane fusion to occur, the S1 and S2 subunits must be cleaved open by transmembrane protease serine 2 (TMPRSS2-1).. ACE2, first identified in 2000, is an enzyme attached to the surface of host cells and is the entry point for SARS-CoV-2. ACE2 is widely distributed throughout the body, being abundantly expressed on nasal epithelial cells, lung alveolar epithelial cells, and small intestinal enterocytes. ACE2 is also expressed in endothelium of vascular beds in organs ...
https://www.merckmanuals.com/professional/resourcespages/covid-19-pathophysiology
Blood vessel and alveoli in lung tissue - Stock Image C023/4110 - Science Photo LibraryBlood vessel and alveoli in lung tissue - Stock Image C023/4110 - Science Photo Library
Blood vessel and alveoli in lung tissue. Coloured scanning electron micrograph (SEM) of a section through a lung, showing red blood cells (round, centre) in a tiny blood vessel (centre) surrounded by alveoli (large spaces). Alveoli are the site of gaseous exchange in the lungs, where oxygen is taken up by the red blood cells and carbon dioxide released for exhalation out of the body. The alveolar walls are lined with a one-cell thick layer of epithelium that oxygen must pass through to reach the blood. - Stock Image C023/4110
http://www.sciencephoto.com/media/640978/view
Bodie granule - Krbové vložky oboustrannéBodie granule - Krbové vložky oboustranné
Monitorujeme aktuální akční letáky Kauflan Lidl, Tesco, . Krmivo Rasco hovězí pro psy 10kg. NovaEqui vzniklo ve spolupráci tří českých fireBODIT TACHOV s. Kompletní krmivo pro dospělé psy. Mléčné granule pod názvem Axcelera-C (A-C) a doplňkové krmivo Novanel, které.. Porovnání cen bodie granule pro psy, srovnání cen bodie granule pro psy na portálu HLEDEJCENY. FROLIC s hovězím masem a zeleninou 500g. Poloměkké masové granule pro dospělé psy všech plemen . Dentální pochoutka jako odměna pro Vašeho psa s kuřecím masem.. In cell biology, lamellar bodies are secretory organelles found in type II alveolar cells in the. Bodit NOVAEQUI Classic 20kg. Involvement of corneodesmosome degradation and lamellar granule transportation in the desquamation process. Medical Molecular Morphology. Akční ceny výrobky a krmivo pro psy 25.. Granule pro psy Bono 17Kč, platí pouze do 20. ...
http://vankorshop.ru/bodie-granule/
Antivirals for Research and Experimental Use | TCI AMERICAAntivirals for Research and Experimental Use | TCI AMERICA
Coronaviruses are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry.1) Coronaviruses cause respiratory tract infections in humans, with most severe cases triggered by SARS, MERS, and, recently, COVID-19 (while the disease is named COVID-19, the virus that causes it was named SARS-CoV-2).2) The lungs are the organs most affected by COVID-19 because the virus (using a special surface glycoprotein) accesses host cells via the enzyme ACE2, which is most abundant in the type II alveolar cells of the lungs.3) Some of the trends in anti-SARS-CoV-2 agent development include the search for the viral proteases 3CLpro or PLpro inhibitors, viral protein expression inhibitors, viral entry to host cells inhibitors, as well as inhibitors of viral replication.4) ...
https://www.tcichemicals.com/US/en/product/pick/antivirals_for_research_and_experimental_use
Perfusion - MedicalPhysiology.co.ukPerfusion - MedicalPhysiology.co.uk
This may occur at the top of the lungs, although not in health. Here the arterial pressure is not quite above alveolar pressure by the time it reaches this height. As such, blood flow through the lung unit does not occur. In health, this means that the arterial pressure at this height is 0 (as this is alveolar pressure) but the application of alveolar pressure (e.g. through IPPV) can require higher arterial pressure ...
http://www.medicalphysiology.co.uk/perfusion.html
SEM of cancer cells in lung alveoli - Stock Image M132/0464 - Science Photo LibrarySEM of cancer cells in lung alveoli - Stock Image M132/0464 - Science Photo Library
Lung cancer. Scanning electron micrograph of cancer cells proliferating inside air sacs (alveoli) in a human lung. These cells are part of an adenocarcinoma, a malignant tumour derived from glandular epithelial tissue. Lung cancer is the leading cause of cancer deaths in men and the second most common cause in woman (after breast cancer). Fewer than 10% of patients survive for five years after diagnosis. The cause of the disease is not always clear; although cigarette smoking is known to cause other forms of lung cancer, such as squamous cell carcinoma, the link between tobacco and adenocarcinoma remains unproven. Magnification x3500 at 10x8 inch size. - Stock Image M132/0464
http://www.sciencephoto.com/media/253970/view
Mouse monoclonal to MPS1 - biobender.comMouse monoclonal to MPS1 - biobender.com
Data Availability StatementThe experimental data is available via Edinburgh DataShare (http://dx. distal lung because of the inability to concurrently access the alveolar sacs and perform real-time GANT61 tyrosianse inhibitor sensing. pH is a key parameter that is tightly regulated in cells and microenvironments. In the lung, a thin film of airway surface liquid lines the air-facing surface of the lungs. The conducting airways are lined with a mucus gel-aqueous sol complex of up to 100 microns in depth called air surface liquid (ASL) whilst the alveolar regions are lined with a complex of alveolar subphase fluid (AVSF) and pulmonary surfactant [1]. ASL pH is acidic compared to blood pH Mouse monoclonal to MPS1 and in healthy humans ASL has been recorded as 6.6 using a bronchoscopically-deployed pH electrode [2]. In preclinical models, the ASL pH has been measured to be between 6.8 and 7.1 [3] and has also been shown to be responsive to changes to blood pH as well as to apical challenges of acid ...
http://biobender.com/tag/mouse-monoclonal-to-mps1/
AlveolusAlveolus
The alveolus is a small, balloon like sac at the end of the small air passages in the lungs (the bronchiole). Oxygen is inhaled and absorbed into the bloodstream through the thin wall of each alveolus, and carbon dioxide is passed the other way (from the blood to the lungs) to be exhaled. There are about 300 million alveoli in each lung.. ...
http://www.innerbody.com/image_card07/card63.html
FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas...FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas...
We have identified in this study the fundamental importance of the transcription factor FoxM1 expressed in alveolar type II cells in the mechanism of alveolar epithelial barrier repair after PA-induced lung injury. We used PA because it induces alveolar injury similar to that encountered in pneumonia (Gray and Kreger, 1979; Sadikot et al., 2006). We showed that type II cell-specific disruption of FoxM1 markedly delayed the recovery of alveolar barrier function as indicated by prolonged neutrophil influx and increased BAL protein concentration. There was a persistent alveolar barrier defect in FoxM1 mutants caused by defective type II cell proliferation and trans-differentiation into type I cells.. Although type I cells comprise ∼95% of the alveolar surface area, studies have shown that type II cells mediate the regeneration of type I alveolar cells and restoration of barrier function after alveolar injury (Evans et al., 1973, 1975). Type II cells after injury thus function as progenitor cells ...
http://jem.rupress.org/content/early/2011/06/22/jem.20102041
Alveolar-capillary barrier financial definition of Alveolar-capillary barrierAlveolar-capillary barrier financial definition of Alveolar-capillary barrier
Definition of Alveolar-capillary barrier in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is Alveolar-capillary barrier? Meaning of Alveolar-capillary barrier as a finance term. What does Alveolar-capillary barrier mean in finance?
https://financial-dictionary.thefreedictionary.com/Alveolar-capillary+barrier
Alveolar capillary dysplasia<...
TY - JOUR. T1 - Alveolar capillary dysplasia. AU - Bishop, Naomi B.. AU - Stankiewicz, Pawel. AU - Steinhorn, Robin H. PY - 2011/7/15. Y1 - 2011/7/15. N2 - Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) is a rare, fatal developmental lung disorder of neonates and infants. This review aims to address recent findings in the etiology and genetics of ACD/MPV and to raise awareness of this poorlyknowndisease, whichmayalso present as milder, unclassified forms. Successively discussed are what is known about the epidemiology, pathogenesis, pathophysiology, diagnostic indicators and approaches, genetic testing, treatment, and cases of delayed onset. The review concludes with suggestions for future directions to answer the many unknowns about this disorder.. AB - Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) is a rare, fatal developmental lung disorder of neonates and infants. This review aims to address recent findings in the etiology ...
https://ucdavis.pure.elsevier.com/en/publications/alveolar-capillary-dysplasia
Best Diffuse Alveolar Hemorrhage Doctor in Bangalore, Diffuse Alveolar Hemorrhage Doctors | CredihealthBest Diffuse Alveolar Hemorrhage Doctor in Bangalore, Diffuse Alveolar Hemorrhage Doctors | Credihealth
Find the best diffuse alveolar hemorrhage doctors in Bangalore. Get guidance from medical experts to select diffuse alveolar hemorrhage specialist in Bangalore from trusted hospitals - credihealth.com
https://www.credihealth.com/doctors/bangalore/diffuse-alveolar-hemorrhage
Alveolar capillary dysplasia - WikipediaAlveolar capillary dysplasia - Wikipedia
Alveolar capillary dysplasia (ACD) is a rare, congenital diffuse lung disease characterized by abnormal blood vessels in the lungs that cause highly elevated pulmonary blood pressure and an inability to effectively oxygenate and remove carbon dioxide from the blood. ACD typically presents in newborn babies within hours of birth as rapid and labored breathing, blue-colored lips or skin, quickly leading to respiratory failure and death. Atypical forms of ACD have been reported with initially milder symptoms and survival of many months before the onset of respiratory failure or lung transplantation. Most cases of ACD are caused by mutations affecting the gene FOXF1 or its nearby enhancer region.[3] Exactly how these mutations lead to abnormal lung development is unknown. Abnormal lung development is characterized by thickened alveolar interstitium, misplacement of pulmonary capillaries away from the alveolar surface, and fewer capillaries overall. This results in poor gas exchange and pulmonary ...
https://en.wikipedia.org/wiki/Alveolar_capillary_dysplasia
Successful Treatment of Diffuse Alveolar Hemorrhage with Activated Factor VII | Annals of Internal Medicine | American College...Successful Treatment of Diffuse Alveolar Hemorrhage with Activated Factor VII | Annals of Internal Medicine | American College...
Background: Life-threatening diffuse alveolar hemorrhage has been successfully treated with recombinant-activated human factor VII (rFVIIa) in 3 different conditions: 2 small-vessel vasculitis-associated diseases and bone marrow transplantation (1). Diffuse alveolar hemorrhage was confirmed by bronchoscopy demonstrating progressively bloodier aliquots of bronchoalveolar lavage fluid ...
https://annals.org/aim/article-abstract/717310/successful-treatment-diffuse-alveolar-hemorrhage-activated-factor-vii
Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type...Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type...
Prophylactic exogenous surfactant therapy is a promising way to attenuate the ischemia and reperfusion (I/R) injury associated with lung transplantation and thereby to decrease the clinical occurrence of acute lung injury and acute respiratory distress syndrome. However, there is little information on the mode by which exogenous surfactant attenuates I/R injury of the lung. We hypothesized that exogenous surfactant may act by limiting pulmonary edema formation and by enhancing alveolar type II cell and lamellar body preservation. Therefore, we investigated the effect of exogenous surfactant therapy on the formation of pulmonary edema in different lung compartments and on the ultrastructure of the surfactant producing alveolar epithelial type II cells. Rats were randomly assigned to a control, Celsior (CE) or Celsior + surfactant (CE+S) group (n = 5 each). In both Celsior groups, the lungs were flush-perfused with Celsior and subsequently exposed to 4 h of extracorporeal ischemia at 4°C and 50 min of
https://respiratory-research.biomedcentral.com/articles/10.1186/1465-9921-9-5/figures/1_636
Full text] Functional consequences for primary human alveolar macrophages followi | IJNFull text] Functional consequences for primary human alveolar macrophages followi | IJN
Functional consequences for primary human alveolar macrophages following treatment with long, but not short, multiwalled carbon nanotubes Sinbad Sweeney, Davide Grandolfo, Pakatip Ruenraroengsak, Teresa D TetleyLung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College London, London, UKPurpose: Multiwalled carbon nanotubes (MWCNTs) are a potential human health hazard, primarily via inhalation. In the lung, alveolar macrophages (AMs) provide the first line of immune cellular defense against inhaled materials. We hypothesized that, 1 and 5 days after treating AMs with short (0.6 µm in length; MWCNT-0.6 µm) and long (20 µm in length; MWCNT-20 µm) MWCNTs for 24 hours, AMs would exhibit increased markers of adverse bioreactivity (cytokine release and reactive oxygen species generation) while also having a modified functional ability (phagocytosis and migration).Methods: Primary human AMs were treated with short and long MWCNTs
https://www.dovepress.com/functional-consequences-for-primary-human-alveolar-macrophages-followi-peer-reviewed-fulltext-article-IJN
Congenital alveolar capillary dysplasia: A developmental vascular anomaly causing persistent pulmonary hypertension of the...
TY - JOUR. T1 - Congenital alveolar capillary dysplasia. T2 - A developmental vascular anomaly causing persistent pulmonary hypertension of the newborn. AU - Khorsand, Jila. AU - Tennant, Robert. AU - Gillies, Concettina. AU - Philipps, Anthony F. PY - 1985. Y1 - 1985. N2 - The clinical course and histologic findings are presented of an infant with an unusual form of pulmonary dysplasia. Characteristic sonographic findings and progressive hypoxemia led to the diagnosis of persistence of the fetal circulation. The patient expired despite ventilatory and pharmacologic intervention. Postmortem findings of severe pulmonary capillary hypoplasia, despite normal anatomical and biochemical parenchymal maturation, were observed. It is suggested that factors controlling pulmonary capillary maturation may be significantly different from those involved in airway and pulmonary parenchymal development... AB - The clinical course and histologic findings are presented of an infant with an unusual form of ...
https://ucdavis.pure.elsevier.com/en/publications/congenital-alveolar-capillary-dysplasia-a-developmental-vascular-
Misdiagnosis of Alveolar capillary dysplasia - RightDiagnosis.comMisdiagnosis of Alveolar capillary dysplasia - RightDiagnosis.com
Misdiagnosis of Alveolar capillary dysplasia including hidden diseases, diagnosis mistakes, alternative diagnoses, differential diagnoses, and misdiagnosis.
http://www.rightdiagnosis.com/a/alveolar_capillary_dysplasia/misdiag.htm
Diffuse Alveolar Hemorrhage (DAH) | MD Nexus
Example: diffuse alveolar hemorrhage in a patient with Wegeners granulomatosis -> note the ground glass infiltrates in the right lung and extensive alveolar filling in the left lung (alveolar hemorrhage was confirmed in the left lower lobe by bronchoscopy ...
http://www.mdnxs.com/topics-2/pulmonary-and-critical-care/Diffuse%20Alveolar%20Hemorrhage/
HKU Scholars Hub: Angiopoietin-1 and keratinocyte growth factor restore the impaired alveolar fluid clearance induced by...HKU Scholars Hub: Angiopoietin-1 and keratinocyte growth factor restore the impaired alveolar fluid clearance induced by...
Background: Acute respiratory distress syndrome (ARDS) caused by high pathogenic avian influenza (HPAI) H5N1 virus infection has resulted in severe illness and high mortality rates among patients. Patients with ARDS are often characterized by impaired alveolar fluid clearance and alveolar edema. An understanding of the mechanism responsible for human alveolar edema will lead to the development of novel therapeutic treatments for ARDS patients. We hypothesized that the paracrine soluble factors angiopoietin-1 (Ang-1) and keratinocyte growth factor (KGF) can resolve alveolar fluid clearance by up-regulating the expression of major sodium and chloride transporters impaired by HPAI H5N1 virus infection. Materials and Methods: Human alveolar epithelial cells grown on transwell inserts were infected with HPAI H5N1 (A/HK/483/97) and low pathogenic avian influenza (LPAI) H1N1 (A/HK/54/98) viruses at MOI 0.1 or incubated with conditioned culture medium containing Ang-1 and/or KGF. At 24 and 48 h ...
http://hub.hku.hk/handle/10722/188187
Role of fibronectin in fibrotic lung disease. A growth factor for human lung fibroblasts<...
TY - JOUR. T1 - Role of fibronectin in fibrotic lung disease. A growth factor for human lung fibroblasts. AU - Bitterman, P.. AU - Rennard, S.. AU - Adelberg, S.. AU - Crystal, R. G.. PY - 1983. Y1 - 1983. N2 - The presence of increased amounts of the matrix component fibronectin together with alveolar macrophage-derived growth factor within the alveolar structures of patients with fibrotic lung disease may play a significant role in the fibrosis characteristic of these disorders, by amplifying the numbers of fibroblasts in the alveolar structures of these patients.. AB - The presence of increased amounts of the matrix component fibronectin together with alveolar macrophage-derived growth factor within the alveolar structures of patients with fibrotic lung disease may play a significant role in the fibrosis characteristic of these disorders, by amplifying the numbers of fibroblasts in the alveolar structures of these patients.. UR - ...
https://experts.nebraska.edu/en/publications/role-of-fibronectin-in-fibrotic-lung-disease-a-growth-factor-for-
Exogenous gene transfer of Rab 3 8 small GTPase ameliorates aberrant lung surfactant homeostasis in Ruby rats | Respiratory...Exogenous gene transfer of Rab 3 8 small GTPase ameliorates aberrant lung surfactant homeostasis in Ruby rats | Respiratory...
Rab38 small GTPase regulates intracellular transport in melanocytes and alveolar type II epithelial cells. Ruby rats carrying Rab38 and other gene mutations exhibit oculocutaneous albinism, bleeding diathesis, and hence, are a rat model of human Hermansky-Pudlak syndrome (HPS). We previously showed that Long Evans Cinnamon (LEC) rats, one strain of the Ruby rats, developed aberrant lung surfactant homeostasis with remarkably enlarged lamellar bodies in alveolar type II cells. A replication-deficient recombinant adenovirus expressing rat Rab38 (Ad-Rab38) was constructed. Alveolar type II cells were isolated from the LEC rats and tested for lung surfactant phosphatidylcholine secretion. The rats were also examined whether exogenous expression of Ad- Rab38 could rescue the altered lung surfactant homeostasis in the lungs. Isolated type II cells infected with Ad-Rab38 exhibited improved secretion patterns of [3H]phosphatidylcholine, i.e. increased basal hyposecretion and decreased agonist-induced
https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-017-0549-2/figures/7
Actin depolymerization is developmentally regulated in rat type II cells exposed to terbutaline.
The type II alveolar epithelial cell synthesizes and secretes pulmonary surfactant. Terbutaline enhances phospholipid release from adult and fetal type II cells. Our hypothesis is that the actin network of microfilaments regulates the secretory activ
http://www.biomedsearch.com/nih/Actin-depolymerization-developmentally-regulated-in/9029633.html
Alveolar carbon monoxide: A comparison of methods of measurement and a study of the effect of change in body posture | Clinical...Alveolar carbon monoxide: A comparison of methods of measurement and a study of the effect of change in body posture | Clinical...
1. We have compared rebreathing, breath-hold and mean alveolar methods of measuring alveolar carbon monoxide (CO), at levels similar to those found in smokers, as a preliminary to using them as indirect measures of carboxyhaemoglobin levels. In the present study alveolar CO levels were raised by rebreathing a 2% CO mixture.. 2. Breath-hold CO was measured after breath-hold times of 0-35 s in 5 s increments. Using generalized linear models, the maximum value for breath-hold CO was estimated to occur at 23 s. Breath-hold CO after a 20 and 25 s breath-hold were similar to and significantly greater than those of less than 20 s or greater than 25 s.. 3. As expired CO increased, the difference between breath-hold and mean alveolar CO became proportionally larger. On average, breath-hold CO was 24% larger than mean alveolar CO.. 4. Rebreathing, breath-hold and mean alveolar CO were compared at four different inspired oxygen concentrations. Expired CO increased significantly with increasing oxygen for ...
https://portlandpress.com/clinsci/article-abstract/74/1/23/74323/Alveolar-carbon-monoxide-A-comparison-of-methods
Diffuse Alveolar Hemorrhage - Lung and Airway Disorders - Merck Manuals Consumer VersionDiffuse Alveolar Hemorrhage - Lung and Airway Disorders - Merck Manuals Consumer Version
Diffuse Alveolar Hemorrhage - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version.
https://www.merckmanuals.com/en-ca/home/lung-and-airway-disorders/autoimmune-disorders-of-the-lungs/diffuse-alveolar-hemorrhage
Top treatments for Diffuse alveolar hemorrhage | PatientsLikeMeTop treatments for Diffuse alveolar hemorrhage | PatientsLikeMe
See how others experience diffuse alveolar hemorrhage. Join the community to connect with others like you and learn about their real-world experiences.
https://www.patientslikeme.com/symptoms/diffuse-alveolar-hemorrhage
Diffuse Alveolar Hemorrhage After Intravenous Thrombolysis for Acute Ischemic Stroke [Turk J Neurol]
Mehtap Kocaturk, Halil Ay, zcan Kocaturk. Diffuse Alveolar Hemorrhage After Intravenous Thrombolysis for Acute Ischemic Stroke. Turk J Neurol. 2019; 25(4): 246- ...
http://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-57701
Senior Scientist, Respiratory Epithelial BiologySenior Scientist, Respiratory Epithelial Biology
Responsibilities:. · Establish human alveolar cell cultures using tissue culture plates and/or organoids in extracellular matrices for mechanism of action studies using viral-based gene therapy vectors.. · Differentiate alveolar type I/II cells from human inducible pluripotent stem cells (iPS cells), other relevant cell sources and/or cultures of primary human alveolar cells.. · Investigate the differentiation status of type II alveolar cells and other respiratory cell types by investigating the expression of established cell markers and/or relevant gene reporter systems using immune-histological staining or molecular techniques.. · Apply biological, biochemical and molecular techniques to investigate viral vector tropism, cell transduction, promoter activity, transgene expression and mechanism of action studies in human airway epithelial cultures.. · Apply molecular biology (PCR, ddPCR, RNA tissue extraction), biochemical analysis (ELISA, FACS), cell culture, cell transfection/infection ...
https://app.trinethire.com/companies/24830-spirovant-sciences-inc/jobs/44659-senior-scientist-respiratory-epithelial-biology
Interalveolar septum - definition of interalveolar septum by The Free DictionaryInteralveolar septum - definition of interalveolar septum by The Free Dictionary
Define interalveolar septum. interalveolar septum synonyms, interalveolar septum pronunciation, interalveolar septum translation, English dictionary definition of interalveolar septum. n. pl. sep·ta A thin partition or membrane that divides two cavities or soft masses of tissue in an organism: the nasal septum; the atrial septum of the...
https://www.thefreedictionary.com/interalveolar+septum
Perfusion heterogeneity in the pulmonary acinus<...
TY - JOUR. T1 - Perfusion heterogeneity in the pulmonary acinus. AU - Tanabe, Nobuhiro. AU - Todoran, Thomas M.. AU - Zenk, Gerald M.. AU - Bunton, Brenda R.. AU - Wagner, Wiltz W.. AU - Presson, Robert. PY - 1998/3. Y1 - 1998/3. N2 - There is little information on the distribution of acinar perfusion because it is difficult to resolve blood flow within such small regions. We hypothesized that the known heterogeneity of arteriolar blood flow and capillary blood flow would result in heterogeneous acinar perfusion. To test this hypothesis, the passage of fluorescent dye boluses through the subpleural microcirculation of isolated dog lobes was videotaped by using fluorescence microscopy. As the videotapes were replayed, dye-dilution curves were recorded from each of the tributary branches of Y-shaped venules that drained an acinus. From the dye curves, we calculated the mean appearance time of each curve. The difference in mean appearance times between venular tributary branches was small in most ...
https://indiana.pure.elsevier.com/en/publications/perfusion-heterogeneity-in-the-pulmonary-acinus
Effect of exogenous surfactants on viability and DNA synthesis in A549, immortalized mouse type II and isolated rat alveolar...Effect of exogenous surfactants on viability and DNA synthesis in A549, immortalized mouse type II and isolated rat alveolar...
In mechanically ventilated preterm infants with respiratory distress syndrome (RDS), exogenous surfactant application has been demonstrated both to decrease DNA-synthesis but also and paradoxically to increase epithelial cell proliferation. However, the effect of exogenous surfactant has not been studied directly on alveolar type II cells (ATII cells), a key cell type responsible for alveolar function and repair. The aim of this study was to investigate the effects of two commercially available surfactant preparations on ATII cell viability and DNA synthesis. Curosurf® and Alveofact® were applied to two ATII cell lines (human A549 and mouse iMATII cells) and to primary rat ATII cells for periods of up to 24 h. Cell viability was measured using the redox indicator resazurin and DNA synthesis was measured using BrdU incorporation. Curosurf® resulted in slightly decreased cell viability in all cell culture models. However, DNA synthesis was increased in A549 and rat ATII cells but decreased in iMATII
https://bmcpulmmed.biomedcentral.com/articles/10.1186/1471-2466-11-11/peer-review
Emerging techniques to assess small airways disease: alveolar nitric oxide and impulse oscillometry<...
TY - JOUR. T1 - Emerging techniques to assess small airways disease. T2 - alveolar nitric oxide and impulse oscillometry. AU - Williamson, P. A.. AU - Vaidyanathan, S.. AU - Lipworth, B. J.. PY - 2008/12. Y1 - 2008/12. M3 - Book/Film/Article review. VL - 63. SP - A19-A19. JO - Thorax. JF - Thorax. SN - 0040-6376. IS - Supplement 7. M1 - S38. ER - ...
https://discovery.dundee.ac.uk/en/publications/emerging-techniques-to-assess-small-airways-disease-alveolar-nitr
RePub, Erasmus University Repository: Alveolar capillary dysplasia with misalignment of the pulmonary veins: clinical,...RePub, Erasmus University Repository: Alveolar capillary dysplasia with misalignment of the pulmonary veins: clinical,...
Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) is a rare and lethal disorder mainly involving the vascular development of the lungs. Since its first description, significant achievements in research have led to a better understanding of the underlying molecular mechanism of ACD/MPV and genetic studies have identified associations with genomic alterations in the locus of the transcription factor FOXF1. This in turn has increased the awareness among clinicians resulting in over 200 cases reported so far, including genotyping of patients in most recent reports. Collectively, this promoted a better stratification of the patient group, leading to new perspectives in research on the pathogenesis. Here, we provide an overview of the clinical aspects of ACD/MPV, including guidance for clinicians, and review the ongoing research into the complex molecular mechanism causing this severe lung disorder.. ...
https://repub.eur.nl/pub/111162
ALVEOLAR CAPILLARY DYSPLASIA | SelfDecode | Genome AnalysisALVEOLAR CAPILLARY DYSPLASIA | SelfDecode | Genome Analysis
Use SelfDecode to get personalized health recommendations based on your genes. Get started today with an existing DNA file or order a SelfDecode DNA kit!
https://selfdecode.com/disease/alveolar-capillary-dysplasia/
Disease InfoSearch - Alveolar Capillary Dysplasia - Definition, causes, resources and support information
Are you looking for disease information or support? Simply type in the name of a disease or condition and Disease InfoSearch will locate quality information from a database of more than 13,000 diseases and thousands of support groups and foundations.
https://www.diseaseinfosearch.org/Alveolar+Capillary+Dysplasia/344
Bronchopneumonia | Profiles RNS
Inflammation of the lung parenchyma that is associated with BRONCHITIS, usually involving lobular areas from TERMINAL BRONCHIOLES to the PULMONARY ALVEOLI. The affected areas become filled with exudate that forms consolidated patches ...
https://researchers.childrensmercy.org/display/4626
Lung Diseases, Interstitial | CTDLung Diseases, Interstitial | CTD
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features ...
http://ctdbase.org/detail.go?type=disease&acc=MESH%3AD017563
Tuberculosis - Infogalactic: the planetary knowledge coreTuberculosis - Infogalactic: the planetary knowledge core
About 90% of those infected with M. tuberculosis have asymptomatic, latent TB infections (sometimes called LTBI),[48] with only a 10% lifetime chance that the latent infection will progress to overt, active tuberculous disease.[49] In those with HIV, the risk of developing active TB increases to nearly 10% a year.[49] If effective treatment is not given, the death rate for active TB cases is up to 66%.[3]. TB infection begins when the mycobacteria reach the pulmonary alveoli, where they invade and replicate within endosomes of alveolar macrophages.[1][50] Macrophages identify the bacterium as foreign and attempt to eliminate it by phagocytosis. During this process, the bacterium is enveloped by the macrophage and stored temporarily in a membrane-bound vesicle called a phagosome. The phagosome then combines with a lysosome to create a phagolysosome. In the phagolysosome, the cell attempts to use reactive oxygen species and acid to kill the bacterium. However, M. tuberculosis has a thick, waxy ...
https://infogalactic.com/info/Tuberculosis
Alveoli - Cellular Development, Function & Anatomy - LifeMap DiscoveryAlveoli - Cellular Development, Function & Anatomy - LifeMap Discovery
Alveoli are the air sacs deep within the lungs, where gas/blood exchange occurs. Alveoli are composed of distal airway epithelium, which consists of type 1 and 2 alveolar epithelial cells (AEC-1 and -2), which specialize in gas exchange and expression of surfactant proteins, respectively.. ...
https://discovery.lifemapsc.com/in-vivo-development/lung/alveoli
Microscope Blood Simulator 2.1 - Scirra ForumsMicroscope Blood Simulator 2.1 - Scirra Forums
Thats a fearsome one, Ancylostoma duodenale. We learnt about it yesterday at the University, and it would make an excellent candidate for a game because of its itinerary: it crosses your skin, reaches blood, right heart, pulmonary circulation, pulmonary alveolus, bronchia, trachea, larynx, esophagus, stomach and intestine, where it bites the wall and stays hanging and feeding from the blood ...
https://www.scirra.com/forum/microscope-blood-simulator-2-1_p495118
Signal transduction mediated by the oncostatin M and IL-31 specific receptor complexes
The goal of this study was to identify the structural elements within the cytoplasmic domains of human IL-31Rα that determines the four response categories of IL-6 cytokines in epithelial cells: (a) the ligand-dependent activation of signal transduction pathways, (b) altered expression of cytokine-responsive genes, (c) suppression of proliferation and (d) changes in cell morphology. In the first part of this study, using the human alveolar epithelial cell line A549 with an increased IL-31Rα expression, we were able to identify signaling specificity of the IL-31 cytokine defined by a prominent activation of STAT3, as well as the MAPK pathways: ERK1/2 and JNK, as well as Akt. The capability of IL-31 to strongly inhibit the proliferation of these cells via up-regulation of the cell cycle inhibitor p27 Kip1 , as well as down-regulation of various cell cycle proteins such Cyclin B1, Cdc2, Rb (retinoblastoma), and Mcm4 was noted. The possible role of IL-31 in cell survival via down-regulation of p53 ...
https://ubir.buffalo.edu/xmlui/handle/10477/47156
Diffuse alveolar damage definition | Drugs.comDiffuse alveolar damage definition | Drugs.com
Definition of diffuse alveolar damage. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
https://www.drugs.com/dict/diffuse-alveolar-damage.html
Pulmonary alveolar epithelial inducible NO synthase gene expression: Regulation by inflammatory mediators<...
TY - JOUR. T1 - Pulmonary alveolar epithelial inducible NO synthase gene expression. T2 - Regulation by inflammatory mediators. AU - Gutierrez, H. H.. AU - Pitt, B. R.. AU - Schwarz, M.. AU - Watkins, S. C.. AU - Lowenstein, C.. AU - Caniggia, I.. AU - Chumley, P.. AU - Freeman, B. A.. PY - 1995/1/1. Y1 - 1995/1/1. N2 - Nitric oxide (·NO) is a short-lived mediator that can be induced by different cytokines and lipopolysaccharide (LPS) in a variety of cell types and produces many physiological and metabolic changes in target cells. In the current study, we show that a combination of cytokines, LPS, and zymosan- activated serum (ZAS; called for convenience cytomix Z) induces production of high concentrations of the NO oxidation products nitrite (NO2/-) and nitrate (NO3/-) by cultured rat fetal lung epithelial type II cells in a time-dependent fashion. Interferon-γ and tumor necrosis factor-α alone did not significantly affect ·NO synthesis, whereas ZAS, LPS, and interleukin- 1β caused only a ...
https://indiana.pure.elsevier.com/en/publications/pulmonary-alveolar-epithelial-inducible-no-synthase-gene-expressi
Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes |...Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes |...
Type I IFNs can be produced by many cell types in response to virus encounter. They act through the IFNAR to induce a large number of genes encoding inhibitors of viral replication and virus assembly that together mediate cell-intrinsic resistance to virus infection and protect from viral spread. Genetic association studies have implicated a role for the type I IFN system in severe lung inflammation induced by RSV infection in some individuals. However, the cellular origin of those type I IFNs and the physiological role of type I IFN-induced inflammation remains unclear. Here, we show that AMs are responsible for production of type I IFNs during lower respiratory tract RSV infection and use the RLR-MAVS pathway for RSV detection. Notably, loss of type I IFN production by AMs results in increased viral replication and exacerbated disease. However, this is not fully attributable to loss of cell-intrinsic viral control but, rather, is associated with lack of recruitment of monocyte-derived ...
http://jem.rupress.org/content/212/5/699
Alveolar concentration of nitric oxide predicts pulmonary function deterioration in scleroderma | ThoraxAlveolar concentration of nitric oxide predicts pulmonary function deterioration in scleroderma | Thorax
The results of this study are consistent with the hypothesis that alveolar inflammation plays an important role in the progression of pulmonary fibrosis leading to SSc-related ILD. They provide strong evidence linking alveolar inflammation (as reflected by high levels of CAno) with losses in lung volumes due to progression of lung fibrosis during the natural course of the disease. Other prediction factors such as chest HRCT and FVC can also accurately detect or assess the extent of lung fibrosis in patients with SSc24 25 and have a relevant predictive value. Thus, a subgroup of patients with SSc with a history of progressive lung disease testified by a large area of ILD on HRCT scanning or lung volume restriction were more likely to have progression of lung disease during long-term follow-up.4 24 These morphological abnormalities of the lung and impaired pulmonary volumes resulted from initial alveolar inflammation that could not be currently measured by lung HRCT or PFTs. In this study, CAno ...
http://thorax.bmj.com/content/67/2/157
Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary DysplasiaMechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia
The expression of αvβ6 integrin is also induced in alveolar type II epithelial cells after acute lung injury (ALI) (Breuss et al., 1995), and in the respiratory epithelium of smokers
https://1library.net/document/zl592ogq-mechanisms-of-lung-injury-in-a-mouse-model-of-bronchopulmonary-dysplasia.html
Studies in the Acetone Concentration in Blood, Urine, and Alveolar Air. III: The Elimination of Acetone through the Lungs |...Studies in the Acetone Concentration in Blood, Urine, and Alveolar Air. III: The Elimination of Acetone through the Lungs |...
Erik Matteo Prochet Widmark; Studies in the Acetone Concentration in Blood, Urine, and Alveolar Air. III: The Elimination of Acetone through the Lungs. Biochem J 1 July 1920; 14 (3-4): 379-394. doi: https://doi.org/10.1042/bj0140379. Download citation file:. ...
https://portlandpress.com/biochemj/article-abstract/14/3-4/379/5574/Studies-in-the-Acetone-Concentration-in-Blood
Alveolar ducts - alveolar sacs - alveoli (300,000,000)Alveolar ducts - alveolar sacs - alveoli (300,000,000)
Respiratory System Lecture Outline Facts: Unicellular organisms - only organisms without resp. system - gasses exchange through membrane. Oxygen in atmosphere: 21% oxygen - anything below 15% humans cant survive Diagram of Resp. Syst.: Mouth\nose - nasal cavity - pharynx - larynx - trachea - bronchi - bronchioles - alveoli (gas exchanges here) Purpose of respiratory system a. supply cells with oxygen b. remove carbon dioxide from cells Upper Resp. Stem: (Nose, Pharynx, Larnyx) Air enters external nares (nostrils) into nasal cavities. Nasal Conchae bones: increase surface area by being folded into 3 ridges Conchae and entire lining of nose covered by mucus membrane - clean dust and debris from air. Three functions of nasal cavity: a. Clean out dirt and dust (mucus and nose hairs) b. Warm the air you breathe (blood vessels in nasal cavity raise air temp.) c. Moisten incoming air. Four pairs of sinuses - drain into nose  Lightens the skull and acts as a resonance chamber for sound. Nasal Cavity ...
http://studylib.net/doc/8991185/alveolar-ducts-%E2%80%93-alveolar-sacs-%E2%80%93-alveoli--300-000-000-
Now: Lung cells from umbilical cord blood cells | LifeEthicsNow: Lung cells from umbilical cord blood cells | LifeEthics
Scientists at the University of Minnesota report that they have produced type II alveolar cells that manufacture surfactant, the lipo-protein that allows lungs to expand and prevent collapse of the tiny airways at the end of each breath. The hope is that this discovery will allow the study of cord blood from babies born with…
https://lifeethics.org/2006/11/02/now-lung-cells-from-umbilical-cord-blood-cells/
Fondation Recherches 3R / Projets / 3R-Project 46-96
Primary human lung cells or cell lines were cultured on a stretchable silastic membrane forming the bottom of a 12-well plexiglas® box. The box was connected to an adult ventilator and ventilated for up to 36 hours at 20 cycles/min with a pressure-volume regimen resembling that of MV. Several lung cell types were tested in this model. The alveolar macrophage was identified as the main cellular source of key inflammatory mediators, such as tumor necrosis factor, the chemokine interleukin (IL)-8, and matrix metalloproteinase-9, produced during mechanical ventilation. Mechanical ventilation also induced low levels of IL-8 secretion by human alveolar epithelial type II-like cells. Other lung cell types such as endothelial cells, bronchial cells, and fibroblasts failed to produce IL-8 in response to mechanical ventilation (1,2). Conclusions and Relevance for 3R ...
http://www.forschung3r.ch/fr/projects/pr_46_96.html
Human Pulmonary Alveolar Epithelial Cell MicroRNA - Science PROHuman Pulmonary Alveolar Epithelial Cell MicroRNA - Science PRO
Human Pulmonary Alveolar Epithelial Cell MicroRNA https://www.sciencepro.com.br/produtos/sc-3207 https://www.sciencepro.com.br/@@site-logo/logo-novo.png ...
https://www.sciencepro.com.br/produtos/sc-3207
Insulin regulates alveolar epithelial function by inducing Na+/K+-ATPase translocation to the plasma membrane in a process...Insulin regulates alveolar epithelial function by inducing Na+/K+-ATPase translocation to the plasma membrane in a process...
Stimulation of Na+/K+-ATPase translocation to the cell surface increases active Na+ transport, which is the driving force of alveolar fluid reabsorption, a process necessary to keep the lungs free of edema and to allow normal gas exchange. Here, we provide evidence that insulin increases alveolar fluid reabsorption and Na+/K+-ATPase activity by increasing its translocation to the plasma membrane in alveolar epithelial cells. Insulin-induced Akt activation is necessary and sufficient to promote Na+/K+-ATPase translocation to the plasma membrane. Phosphorylation of AS160 by Akt is also required in this process, whereas inactivation of the Rab GTPase-activating protein domain of AS160 promotes partial Na+/K+-ATPase translocation in the absence of insulin. We found that Rab10 functions as a downstream target of AS160 in insulin-induced Na+/K+-ATPase translocation. Collectively, these results suggest that Akt plays a major role in Na+/K+-ATPase intracellular translocation and thus in alveolar fluid ...
http://jcs.biologists.org/content/early/2010/03/23/jcs.066464
KAKEN - Research Projects | Development of synthetic surfactant and its protective effect on alveolar type II cell (KAKENHI...KAKEN - Research Projects | Development of synthetic surfactant and its protective effect on alveolar type II cell (KAKENHI...
Principal Investigator：TASHIRO Katsumi, Project Period (FY)：2003 - 2004, Research Category：Grant-in-Aid for Scientific Research (C), Section：一般, Research Field：Anesthesiology/Resuscitation studies
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15591621/
alveolar duct function in respiratory system Archives - Human Anatomy System
alveolar duct function in respiratory system pictures, alveolar duct function in respiratory system photos, alveolar duct function in respiratory system image gallery
http://www.anatomylibrary.us/tag/alveolar-duct-function-in-respiratory-system/
Pesquisa | Portal Regional da BVSPesquisa | Portal Regional da BVS
Reproducible and unbiased methods to quantify alveolar structure are important for research on many lung diseases. However, manually estimating alveolar structure through stereology is time consuming and inter-observer variability is high. The objective of this work was to develop and validate a fast, reproducible and accurate (semi-)automatic alternative. A FIJI-macro was designed that automatically segments lung images to binary masks, and counts the number of test points falling on tissue and the number of intersections of the air-tissue interface with a set of test lines. Manual selection remains necessary for the recognition of non-parenchymal tissue and alveolar exudates. Volume density of alveolar septa ([Formula: see text]) and mean linear intercept of the airspaces (Lm) as measured by the macro were compared to theoretical values for 11 artificial test images and to manually counted values for 17 lungs slides using linear regression and Bland-Altman plots. Inter-observer agreement ...
https://pesquisa.bvsalud.org/portal/?lang=pt&q=mh:%22Interpreta%C3%A7%C3%A3o%20de%20Imagem%20Radiogr%C3%A1fica%20Assistida%20por%20Computador%22
Pulmonary alveolusPulmonary alveolus
A pulmonary alveolus (plural: alveoli, from Latin alveolus, "little cavity"), also known as an air sac or air space, is one of ... Wikimedia Commons has media related to Pulmonary alveoli. Pulmonary+Alveoli at the US National Library of Medicine Medical ... Pulmonary alveolar microlithiasis is a rare lung disorder of small stone formation in the alveoli. A pulmonary contusion is a ... They are also called pulmonary macrophages, and dust cells. Insufficient surfactant in the alveoli is one of the causes that ...
https://en.wikipedia.org/wiki/Pulmonary_alveolus
Alveolar capillary dysplasiaAlveolar capillary dysplasia
... misplaced pulmonary veins adjacent to pulmonary arteries, abnormal alveoli with thickened interstitia and abnormal capillary ... Pulmonary vasodilators like sildenafil or inhaled nitric oxide can be used to reduce pulmonary blood pressures. For those with ... MacMahon HE (July 1948). "Congenital alveolar dysplasia; a developmental anomaly involving pulmonary alveoli". Pediatrics. 2 (1 ... ACD-causing mutations result in abnormal development of lung vasculature and alveoli. In ACD, the interstitium of alveoli is ...
https://en.wikipedia.org/wiki/Alveolar_capillary_dysplasia
Pores of KohnPores of Kohn
Desplechain C.; Foliguet B.; Barrat E.; Grignon G.; Touati F. (1983). "[The pores of Kohn in pulmonary alveoli]". Bull Eur ... 2005). Paediatric pulmonary function testing : 41 tables ([Online-Ausg.] ed.). Basel [u.a.]: Karger. pp. 6. ISBN 3-8055-7753-2 ... The pores of Kohn (also known as interalveolar connections or alveolar pores) are discrete holes in walls of adjacent alveoli. ... They also equalize the pressure in adjacent alveoli and, combined with increased distribution of surfactant, thus play an ...
https://en.wikipedia.org/wiki/Pores_of_Kohn
Pulmonary arteryPulmonary artery
... which lead to the capillaries that surround the pulmonary alveoli. The pulmonary arteries are blood vessels that carry systemic ... Pulmonary circuit Transverse section of thorax, showing relations of pulmonary artery. Pulmonary artery Pulmonary artery.Deep ... The largest pulmonary artery is the main pulmonary artery or pulmonary trunk from the heart, and the smallest ones are the ... The pulmonary trunk splits into the right and the left main pulmonary artery. The left main pulmonary artery is shorter than ...
https://en.wikipedia.org/wiki/Pulmonary_artery
Pulmonary alveolar proteinosisPulmonary alveolar proteinosis
The surrounding alveoli and pulmonary interstitium remain relatively normal. Electron microscopy of the sample, although not ... GATA2 mutation-based pulmonary alveolar proteinosis is associated with normal levels of GM-CSF and commonly improves or is ... Pulmonary alveolar proteinosis (PAP) is a rare lung disorder characterized by an abnormal accumulation of surfactant-derived ... Hereditary pulmonary alveolar proteinosis is a recessive genetic condition in which individuals are born with genetic mutations ...
https://en.wikipedia.org/wiki/Pulmonary_alveolar_proteinosis
Pneumocytic hyperplasiaPneumocytic hyperplasia
... is an hyperplasia of pneumocytes lining pulmonary alveoli. Pulmonary atypical adenomatous hyperplasia ... v t e (Pulmonary lesion, All stub articles, Medical sign stubs). ...
https://en.wikipedia.org/wiki/Pneumocytic_hyperplasia
Marcello MalpighiMarcello Malpighi
West, John B. (1 February 2013). "Marcello Malpighi and the discovery of the pulmonary capillaries and alveoli". American ... In 1661 he identified and described the pulmonary and capillary network connecting small arteries with small veins. Malpighi's ... structures now known as alveoli he used to describe the air pathway as continuous inhalation and exhalation with the alveoli at ... with the dissection of sheep and other mammals where he would inject black ink into the pulmonary artery. Tracing the inks ...
https://en.wikipedia.org/wiki/Marcello_Malpighi
Viral pneumoniaViral pneumonia
The pulmonary alveoli fill with fluid or pus making it difficult to breathe. Pneumonia can be caused by bacteria, viruses, ... which cause leaking of fluid into the alveoli. The combination of cellular destruction and fluid-filled alveoli interrupts the ... There, the virus invades the cells lining the airways and the alveoli. This invasion often leads to cell death either through ... Colby, Thomas V.; Zaki, Sherif R.; Feddersen, Richard M.; Nolte, Kurt B. (October 2000). "Hantavirus Pulmonary Syndrome Is ...
https://en.wikipedia.org/wiki/Viral_pneumonia
PentoxyverinePentoxyverine
Its anticholinergic properties can theoretically relax the pulmonary alveoli and reduce phlegm production. Spasmolytic and ...
https://en.wikipedia.org/wiki/Pentoxyverine
Turkestan red pikaTurkestan red pika
The frontal bone has no alveolus (hollow cavity in bone. Not the same structure as a pulmonary alveolus) above it. The front ...
https://en.wikipedia.org/wiki/Turkestan_red_pika
HemoglobinHemoglobin
This process occurs in the pulmonary capillaries adjacent to the alveoli of the lungs. The oxygen then travels through the ... This elevation may be caused by congenital heart disease, cor pulmonale, pulmonary fibrosis, too much erythropoietin, or ... such as those present in the alveoli), the relaxed (high affinity, R) state is favoured. Inversely, at low partial pressures ( ...
https://en.wikipedia.org/wiki/Hemoglobin
Pulmonary atypical adenomatous hyperplasiaPulmonary atypical adenomatous hyperplasia
Atypical adenomatous hyperplasia (AAH) is a hyperplastic lesion of the epithelial lining of pulmonary alveoli. A multi-step ... v t e (Pulmonary lesion, All stub articles, Medical sign stubs). ...
https://en.wikipedia.org/wiki/Pulmonary_atypical_adenomatous_hyperplasia
Respiratory diseaseRespiratory disease
Pulmonary interstitial emphysema is the condition of air escaping overdistended alveoli into the pulmonary interstitium. It is ... Pulmonary vascular diseases are conditions that affect the pulmonary circulation. Examples are:[citation needed] Pulmonary ... Pulmonary edema, leakage of fluid from capillaries of the lung into the alveoli (or air spaces). It is usually due to ... Pulmonary hemorrhage, inflammation and damage to capillaries in the lung resulting in blood leaking into the alveoli. This may ...
https://en.wikipedia.org/wiki/Respiratory_disease
Ascaris lumbricoidesAscaris lumbricoides
The larvae then break through the walls of the pulmonary capillaries to enter the alveoli. The juvenile worms then migrate from ... From there, the larvae then pass through the heart to enter the pulmonary circulation. ... Accompanying pathological symptoms include pulmonary infiltration, eosinophilia (symptoms of the overabundance of eosinophils ... the alveoli, through the bronchioles and bronchi, and into the trachea. An acute inflammatory reaction can occur if some of the ...
https://en.wikipedia.org/wiki/Ascaris_lumbricoides
Horizontal transfer of mitochondriaHorizontal transfer of mitochondria
"Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury". Nature ... Bone marrow-derived stem cells (BMSCs) injected into mice with acute lung injury transfer their mitochondria to lung alveoli ...
https://en.wikipedia.org/wiki/Horizontal_transfer_of_mitochondria
Tunneling nanotubeTunneling nanotube
April 2012). "Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung ...
https://en.wikipedia.org/wiki/Tunneling_nanotube
Pulmonary gas pressuresPulmonary gas pressures
Alveolar-arterial gradient Diffusing capacity Pulmonary alveolus Dugdale DC, Zieve D. Gasometría arterial. Medline Plus. 09/01/ ... The rest of the difference is due to the continual uptake of oxygen by the pulmonary capillaries, and the continual diffusion ... of CO2 out of the capillaries into the alveoli. The alveolar pO2 is not routinely measured but is calculated from blood gas ...
https://en.wikipedia.org/wiki/Pulmonary_gas_pressures
Hookworm infectionHookworm infection
Eventually, the L3 larvae enter the lungs through the pulmonary capillaries and break out into the alveoli. They then travel up ... Additionally, cough and pneumonitis may result as the larvae begin to break into the alveoli and travel up the trachea. Then ...
https://en.wikipedia.org/wiki/Hookworm_infection
Inhalation exposureInhalation exposure
Most gas exchange occurs in the pulmonary region due to the alveoli, which contain a large surface area. Scientists have ... Insoluble particles that enter the pulmonary region cause swelling of the alveoli, coughing, and shortness of breath. Carbon ... Since the gas takes time to build up in the pulmonary region, an inhaled concentration of 600 ppm would cause a headache and ... High CO levels build up in the pulmonary region over several hours, and equilibrate with inhaled CO concentrations. Exposure to ...
https://en.wikipedia.org/wiki/Inhalation_exposure
Multifocal micronodular pneumocyte hyperplasiaMultifocal micronodular pneumocyte hyperplasia
... hyperplasia of pneumocytes lining pulmonary alveoli). Several synonymous terms have been done for this entity: adenomatoid ... Well-demarcated, nodular lesions ranging 2-5 mm in pulmonary parenchyma. Type II pneumocytes without nuclear atypia lined ... Microscopical images Microscopical images Microscopical images v t e (Pulmonary lesion, All stub articles, Medical sign stubs) ... "Tuberous sclerosis complex complicated by pulmonary multinodular shadows". Internal Medicine (Tokyo, Japan). 45 (5): 275-8. doi ...
https://en.wikipedia.org/wiki/Multifocal_micronodular_pneumocyte_hyperplasia
Post-cardiac arrest syndromePost-cardiac arrest syndrome
The oxygen accumulation in the alveoli encourages ROS production which then leads to pulmonary damage. This pulmonary-specific ... Lung complications, such as pulmonary contusion and pulmonary edema, may result from other aspects of PCAS such as CPR and left ... However, during cardiac arrest, the body is in circulatory and pulmonary arrest. Oxygen is no longer being ventilated by the ... Finally, pneumonia is a common pulmonary complication due to multifactoral mechanisms including: loss of airway protection, ...
https://en.wikipedia.org/wiki/Post-cardiac_arrest_syndrome
DrowningDrowning
Aspirated water that reaches the alveoli destroys the pulmonary surfactant, which causes pulmonary edema and decreased lung ... Specifically, upon reaching the alveoli, hypotonic liquid found in freshwater dilutes pulmonary surfactant, destroying the ... Treatment of pulmonary complication from drowning is dependent on the amount of lung injury that occurred during the incident. ... Even small quantities can cause the extrusion of liquid into the lungs (pulmonary edema) over the following hours; this reduces ...
https://en.wikipedia.org/wiki/Drowning
ParenchymaParenchyma
Lung parenchyma is the substance of the lung that is involved with gas exchange and includes the pulmonary alveoli. The liver ...
https://en.wikipedia.org/wiki/Parenchyma
Freediving blackoutFreediving blackout
Pulmonary alveolus - Hollow cavity found in the lungs, for a discussion of gas pressure in the lung. Apnea - Suspension of ... Suctioning of pulmonary oedema fluid should be balanced against the need for oxygenisation. The target of ventilation is to ... It is a protective reflex against pulmonary aspiration; this reflex may be triggered when the vocal cords or the area of the ...
https://en.wikipedia.org/wiki/Freediving_blackout
Hepatization of lungsHepatization of lungs
Red hepatization is when there are red blood cells, neutrophils, and fibrin in the pulmonary alveolus/ alveoli; it precedes ...
https://en.wikipedia.org/wiki/Hepatization_of_lungs
Toll-like receptor 2Toll-like receptor 2
... pulmonary alveoli, renal tubules, and the Bowman's capsules in renal corpuscles. TLR2 is also expressed by intestinal ...
https://en.wikipedia.org/wiki/Toll-like_receptor_2
Toxicodendron vernixToxicodendron vernix
... smoke inhaled by burning poison sumac leads to life-threatening pulmonary edema whereby fluid enters the alveoli. Toxicodendron ...
https://en.wikipedia.org/wiki/Toxicodendron_vernix
Necator americanusNecator americanus
Once there, it burrows through the pulmonary alveoli and travels up the trachea, where it is swallowed and carried to the small ...
https://en.wikipedia.org/wiki/Necator_americanus
SepsisSepsis
Increased permeability of the lung vessels causes leaking of fluids into alveoli, which results in pulmonary edema and acute ... and pulmonary embolism. Sepsis requires immediate treatment with intravenous fluids and antimicrobials. Ongoing care often ... pulmonary embolism, thyrotoxicosis, anaphylaxis, adrenal insufficiency, and neurogenic shock. Hyperinflammatory syndromes such ...
https://en.wikipedia.org/wiki/Sepsis
Meconium aspiration syndromeMeconium aspiration syndrome
Once within the terminal bronchioles and alveoli, the meconium triggers inflammation, pulmonary edema, vasoconstriction, ... Chronic hypoxia will lead to an increase in pulmonary vascular smooth muscle tone and persistent pulmonary hypertension causing ... Persistent pulmonary hypertension (PPHN) is the failure of the foetal circulation to adapt to extra-uterine conditions after ... It functions to lower surface tension (to allow for lung expansion during inspiration), stabilise alveoli at the end of ...
https://en.wikipedia.org/wiki/Meconium_aspiration_syndrome
Scuba setScuba set
... as the expansion of gas in the lungs could over-expand the lung air spaces and rupture the alveoli and their capillaries, ... allowing lung gases to get into the pulmonary return circulation, the pleura, or the interstitial areas near the injury, where ...
https://en.wikipedia.org/wiki/Scuba_set
Blood-air barrierBlood-air barrier
It exists to prevent air bubbles from forming in the blood, and from blood entering the alveoli. It is formed by the type I ... This can be a result of several possible causes, including blast injury, swimming-induced pulmonary edema, and breathing gas ... Barrier formed by the continuous blood capillaries in the thymic cortex Pulmonary vein - Veins that transfer oxygenated blood ... Failure of the barrier may occur in a pulmonary barotrauma. ...
https://en.wikipedia.org/wiki/Blood–air_barrier
Tuft cellTuft cell
... s are found in the intestine, and stomach, and as pulmonary brush cells in the respiratory tract, from nose to alveoli ...
https://en.wikipedia.org/wiki/Tuft_cell
Influenza A virus subtype H1N1Influenza A virus subtype H1N1
The study authors suggest physician evaluation via contrast enhanced CT scans for the presence of pulmonary emboli when caring ... resulting in the destruction of lung cells and secretion of blood and mucus into the alveoli and airways. This makes it ... warned that H1N1 flu can cause pulmonary embolism, surmised as a leading cause of death in this pandemic. ... 2 response to H1N1 influenza which may be responsible for the systemic inflammatory response syndrome that causes pulmonary ...
https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H1N1
Wilson-Mikity syndromeWilson-Mikity syndrome
Upon autopsy, alveolar collapse and alveoli rupture can be seen. This can reduce the number of capillaries within the system ... pulmonary dysmaturity syndrome)". Canadian Medical Association Journal. 100 (19): 909-12. PMC 1945995. PMID 5789544. Lehman DH ... Infant respiratory distress syndrome Bronchopulmonary dysplasia Chronic obstructive pulmonary disease Retrolental Fibroplasia ...
https://en.wikipedia.org/wiki/Wilson–Mikity_syndrome
BronchoconstrictionBronchoconstriction
Muscarinic antagonists (anti-cholinergics): Blocking the muscarinic acetylcholine receptors in pulmonary smooth muscle tissue ... and increase delivery of air to the alveoli during respiration. Unlike the SABAs, these medications do not provide relief of ... Medications that stimulate the β2 receptor subtype on pulmonary smooth muscle will result in smooth muscle relaxation, ... more specifically in persistent or severe asthma and chronic obstructive pulmonary disease (COPD).[citation needed] These ...
https://en.wikipedia.org/wiki/Bronchoconstriction
PneumonitisPneumonitis
Alveoli are the primary structure affected by pneumonitis. Any particles that are smaller than 5 microns can enter the alveoli ... Some degree of pulmonary fibrosis may be evident in a CT which is indicative of chronic pulmonary inflammatory processes. ... "Evaluation of the Pulmonary Patient - Pulmonary Disorders". Merck Manuals Professional Edition. Retrieved 2020-03-26. " ... "Hypersensitivity Pneumonitis - Pulmonary Disorders". Merck Manuals Professional Edition. Retrieved 2020-03-26. Keffer S, Guy CL ...
https://en.wikipedia.org/wiki/Pneumonitis
Lecithin-sphingomyelin ratioLecithin-sphingomyelin ratio
Lungs require surfactant, a soap-like substance, to lower the surface pressure of the alveoli in the lungs. This is especially ... The outward flow of pulmonary secretions from the fetal lungs into the amniotic fluid maintains the level of lecithin and ... Spillman T, Cotton DB (1989). "Current perspectives in assessment of fetal pulmonary surfactant status with amniotic fluid". ...
https://en.wikipedia.org/wiki/Lecithin–sphingomyelin_ratio
Farmers lungFarmer's lung
Reyes CN, Wenzel FJ, Lawton BR, Emanuel DA (February 1982). "The pulmonary pathology of farmer's lung disease". Chest. 81 (2): ... IgG antibodies combined with the inhaled allergen to form immune complexes in the walls of the alveoli in the lungs. This ... Organic dust toxic syndrome Enelow RI (2008). Fishman's Pulmonary Diseases and Disorders (4th ed.). McGraw-Hill. pp. 1161-1172 ...
https://en.wikipedia.org/wiki/Farmer's_lung
Dead space (physiology)Dead space (physiology)
The quantity of CO2 exhaled from the healthy alveoli is diluted by the air in the conducting airways (anatomic dead space) and ... West, JB (2009). "Comparative physiology of the pulmonary blood-gas barrier: the unique avian solution". American Journal of ... Unfortunately, the concentration of carbon dioxide (CO2) in alveoli is required to use the equation but this is not a single ... Burke, TV; Küng, M; Burki, NK (1989). "Pulmonary gas exchange during histamine-induced bronchoconstriction in asthmatic ...
https://en.wikipedia.org/wiki/Dead_space_(physiology)
Acute inhalation injuryAcute inhalation injury
2008) Trial of prophylactic inhaled steroids to prevent or reduce pulmonary function decline, pulmonary symptoms, and airway ... the endothelium and the basement membrane of the alveolus. In the acute phase of ALI, there is increased permeability of this ... 2008) Trial of prophylactic inhaled steroids to prevent or reduce pulmonary function decline, pulmonary symptoms, and airway ... 12 h before symptoms of pulmonary edema develop. Acute lung injury (ALI), also called non-cardiogenic pulmonary edema, is ...
https://en.wikipedia.org/wiki/Acute_inhalation_injury
AscariasisAscariasis
During pulmonary disease, larvae may be found in fluids aspirated from the lungs. White blood cell counts may demonstrate ... There they break into the alveoli and pass up the trachea, where they are coughed up and may be swallowed. The larvae then pass ... Pulmonary manifestations take place during larval migration and may present as Loeffler's syndrome, a transient respiratory ... Some patients may have pulmonary symptoms or neurological disorders during migration of the larvae. There are generally few or ...
https://en.wikipedia.org/wiki/Ascariasis
Hepatopulmonary syndromeHepatopulmonary syndrome
There is an increased gradient between the partial pressure of oxygen in the alveoli of the lung and adjacent arteries ( ... Intravenous microbubbles (> 10 micrometers in diameter) from agitated normal saline that are normally obstructed by pulmonary ...
https://en.wikipedia.org/wiki/Hepatopulmonary_syndrome
Tobacco smokingTobacco smoking
Oh, CK; Murray, LA; Molfino, NL (February 2012). "Smoking and Idiopathic Pulmonary Fibrosis". Pulmonary Medicine. Hindawi ... The lungs contain some 300 million alveoli, which amounts to a surface area of over 70 m2 (about the size of a tennis court). ... chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), emphysema, and various types and subtypes of ... The resulting smoke is then inhaled and the active substances absorbed through the alveoli in the lungs or the oral mucosa. ...
https://en.wikipedia.org/wiki/Tobacco_smoking
Acid-base homeostasisAcid-base homeostasis
The respiratory centres then determine the average rate of ventilation of the alveoli of the lungs, to keep the PCO2 in the ... Levitzky, Michael G. (2013). Pulmonary physiology (Eighth ed.). New York: McGraw-Hill Medical. p. Chapter 9. Control of ...
https://en.wikipedia.org/wiki/Acid–base_homeostasis
Armstrong limitArmstrong limit
At or above the Armstrong limit, exposed body fluids such as saliva, tears, urine, and the liquids wetting the alveoli within ... The garment counters the outward expansion of the pilot's chest to prevent pulmonary barotrauma until the pilot can descend to ...
https://en.wikipedia.org/wiki/Armstrong_limit
Hyperinflation therapyHyperinflation therapy
Pulmonary Function Testing Respiratory therapy Robson WP (1998). "To bag or not to bag? Manual hyperinflation in intensive care ... The therapy involves applying volumes greater than normal to reinflate the collapsed alveoli in the lungs. There are many ... in the mechanically ventilated patient with chronic obstructive pulmonary disease". Chron Respir Dis. 2 (4): 199-207. doi: ...
https://en.wikipedia.org/wiki/Hyperinflation_therapy
Computed tomography of the chestComputed tomography of the chest
... alveoli), contrasted scan of the lungs (to look for lung cancer and abscesses), and CT pulmonary angiogram (to look for lung ... perfusion and pulmonary embolism). Bhalla AS, Das A, Naranje P, Irodi A, Raj V, Goyal A (2019). "Imaging protocols for CT chest ...
https://en.wikipedia.org/wiki/Computed_tomography_of_the_chest
AtelectasisAtelectasis
It is a condition where the alveoli are deflated down to little or no volume, as distinct from pulmonary consolidation, in ... argon and traces of other gases). Since oxygen is exchanged at the alveoli-capillary membrane, nitrogen is a major component ... Another common cause is pulmonary tuberculosis. Smokers and the elderly are also at an increased risk. Outside of this context ... Factors also associated with the development of atelectasis include: age, presence of chronic obstructive pulmonary disease or ...
https://en.wikipedia.org/wiki/Atelectasis
Evolution of mammalsEvolution of mammals
... pulmonary alveoli, bronchioles and a developed diaphragm for a larger surface area for breathing, enucleated erythrocytes, a ...
https://en.wikipedia.org/wiki/Evolution_of_mammals
Air pollutionAir pollution
The mechanisms linking air pollution to increased cardiovascular mortality are uncertain, but probably include pulmonary and ... These particles can get past the defenses of our upper airways to penetrate deep into our lungs and reach the alveoli ... From ... Research has demonstrated increased risk of developing asthma and chronic obstructive pulmonary disease (COPD) from increased ... Sunyer, J. (2001). "Urban air pollution and Chronic Obstructive Pulmonary disease: a review". European Respiratory Journal. 17 ...
https://en.wikipedia.org/wiki/Air_pollution
Index of anatomy articlesIndex of anatomy articles
... ganglion ptosis puberty pubic hair pubic symphysis pubis pudendal nerve pulmonary pulmonary alveolus pulmonary trunk pulmonary ... colic artery left common carotid artery left gastroepiploic artery left mainstem bronchi left marginal artery left pulmonary ... artery right common carotid artery right gastroepiploic artery right mainstem bronchi right marginal artery right pulmonary ... agonist alar ligament albuginea alimentary allantois allocortex alpha motor neurons alveolar artery alveolar process alveolus ...
https://en.wikipedia.org/wiki/Index_of_anatomy_articles
SmokingSmoking
The lungs consist of several million tiny bulbs called alveoli that altogether have an area of over 70 m2 (about the area of a ... as the gas diffuses directly into the pulmonary vein, then into the heart and from there to the brain) and affects the user ... heart attacks and chronic obstructive pulmonary disease (COPD). Smoking during pregnancy may cause ADHD to a fetus. Smoking is ... "ABC of chronic obstructive pulmonary disease. Definition, epidemiology, and risk factors". BMJ. 332 (7550): 1142-44. doi: ...
https://en.wikipedia.org/wiki/Smoking
Upper airway resistance syndromeUpper airway resistance syndrome
Current Opinion in Pulmonary Medicine. 10 (6): 461-467. doi:10.1097/01.mcp.0000143689.86819.c2. PMID 15510051. S2CID 37248742. ... expanders cannot achieve maxillary expansion in adults as the mechanical forces instead tip the teeth and dental alveoli. Mini- ...
https://en.wikipedia.org/wiki/Upper_airway_resistance_syndrome
AmphibianAmphibian
The lungs in amphibians are primitive compared to those of amniotes, possessing few internal septa and large alveoli, and ... When the ventricle starts contracting, deoxygenated blood is pumped through the pulmonary artery to the lungs. Continued ...
https://en.wikipedia.org/wiki/Amphibian
Eosinophilic pneumoniaEosinophilic pneumonia
Pulmonary function testing usually reveals a restrictive process with reduced diffusion capacity for carbon monoxide. Chronic ... These cells cause disruption of the normal air spaces (alveoli) where oxygen is extracted from the atmosphere. Several ... Asthma Parasitic pneumonia Pneumonia Bain GA, Flower CD (1996). "Pulmonary eosinophilia". European Journal of Radiology. 23 (1 ... Polyarteritis nodosa Parasitic infections Tropical pulmonary eosinophilia Tuberculosis Fungal infection Sarcoidosis Drug ...
https://en.wikipedia.org/wiki/Eosinophilic_pneumonia
Nitrogen dioxide poisoningNitrogen dioxide poisoning
... nitric acid which causes pulmonary edema and pneumonitis leading to the inflammation of the bronchioles and pulmonary alveolus ... resulting in apoptosis or inflammation of the bronchioles and pulmonary alveolus in mild cases. On migrating to the bloodstream ... Chest radiography may be used in diagnosis and the baseline could be established with pulmonary function testing. There is no ... If chronic exposure causes lung damage, it could take several days or months for the pulmonary function to improve. Meanwhile, ...
https://en.wikipedia.org/wiki/Nitrogen_dioxide_poisoning
Exercise-induced pulmonary hemorrhageExercise-induced pulmonary hemorrhage
... the fragile membrane separating blood in the pulmonary capillaries from the air-filled alveoli) and consequent hemorrhage into ... Pulmonary capillary transmural pressure is determined by pulmonary capillary pressure and airway pressure. The horse has very ... Hinchcliff, Kenneth W. "Exercise-Induced Pulmonary Hemorrhage". Pulmonary Hemorrhage (PDF). Versailles, Kentucky: Kentucky ... "Relationship of pulmonary arterial pressure to pulmonary haemorrhage in exercising horses". Equine Veterinary Journal. 32 (5): ...
https://en.wikipedia.org/wiki/Exercise-induced_pulmonary_hemorrhage
Browsing by Subject Pulmonary AlveoliBrowsing by Subject "Pulmonary Alveoli"
JavaScript is disabled for your browser. Some features of this site may not work without it ...
https://extranet.who.int/iris/restricted/browse?locale-attribute=en&type=mesh&authority=Pulmonary+Alveoli
7-3 Pleural Cavity Alveoli Pulmonary Circulation Development - MSU MediaSpace7-3 Pleural Cavity Alveoli Pulmonary Circulation Development - MSU MediaSpace
7-3 Pleural Cavity Alveoli Pulmonary Circulation Development From JIT CHM Jit Media ...
https://mediaspace.msu.edu/media/7-3+Pleural+Cavity+Alveoli+Pulmonary+Circulation+Development/1_us7ggloi
HS23 - Lobule of the Lung with Additional Model Pulmonary AlveoliHS23 - Lobule of the Lung with Additional Model Pulmonary Alveoli
Somso Lobule of the Lung with Additional Model Pulmonary Alveoli, Anatomical Model ... Somso Lobule of the Lung with Additional Model Pulmonary Alveoli, Anatomical Model ... Somso Lobule of the Lung with Additional Model Pulmonary Alveoli, Anatomical Model. ... Model of an adjacent alveolus: enlarged approx. 1000 times. *Representation of the alveolar wall, its vessels, the epithelial ...
https://www.southernbiological.com/anatomy-models/lung-and-larynx/hs23-lobule-of-the-lung-with-additional-model-pulmonary-alveoli/
Intra-alveolar haemorrhage in sudden infant death syndrome: a cause for concern?Intra-alveolar haemorrhage in sudden infant death syndrome: a cause for concern?
Pulmonary Alveoli* * Sudden Infant Death / diagnosis * Sudden Infant Death / etiology* ...
https://pubmed.ncbi.nlm.nih.gov/10645223/?dopt=Abstract
Browsing by SubjectBrowsing by Subject
Pulmonary Alveoli [‎1]‎. Pulmonary Arterial Hypertension [‎3]‎. Pulmonary Disease, Chronic Obstructive [‎30]‎. ...
https://apps.who.int/iris/browse?rpp=20&offset=4920&etal=-1&sort_by=-1&type=mesh&starts_with_previous=R&order=ASC
IJMS | Free Full-Text | Graphene Nanomaterials: Synthesis, Biocompatibility, and CytotoxicityIJMS | Free Full-Text | Graphene Nanomaterials: Synthesis, Biocompatibility, and Cytotoxicity
Magnified images from the line squares are the enlarged pulmonary alveoli. Dark spots are GO-cell complexes in livers. For ... Magnified images from the line squares are the enlarged pulmonary alveoli. Dark spots are GO-cell complexes in livers. For ... No pulmonary thromboembolism. [131]. GO. KM mice. 0.1, 0.25 and 0.4 mg per mouse. Intravenous injection. GOs found in the lung ... Biodistribution and pulmonary toxicity of intratracheally instilled graphene oxide in mice. NPG Asia Mater. 2013, 5, e44. [ ...
https://www.mdpi.com/1422-0067/19/11/3564
CN106142487B - Jet forming machine and its melten gel screw rod - Google Patents
210000003456 Pulmonary Alveoli Anatomy 0.000 description 1 * 238000010521 absorption reaction Methods 0.000 description 1 ... liquid phase groove 315 is extended to entire alveolus, and continues the tail end depth H of third compression section I3 ...
https://patents.google.com/patent/CN106142487B/en
Drowning: Background, Etiology, EpidemiologyDrowning: Background, Etiology, Epidemiology
Protein-rich fluid then exudes rapidly into the alveoli and pulmonary interstitium. Compliance is reduced, the alveolar- ... Pulmonary hypertension may result from the release of pulmonary inflammatory mediators, increasing right ventricular afterload ... Postobstructive pulmonary edema following laryngospasm and hypoxic neuronal injury with resultant neurogenic pulmonary edema ... Pulmonary effects. The target organ of submersion injury is the lung. Aspiration of as little as 1-3 mL/kg of fluid leads to ...
https://www.medscape.com/answers/772753-111523/what-are-the-signs-and-symptoms-of-hyperstimulation-of-the-sympathetic-nervous-system-in-drowning
Volume 15(10) 2009 (22)Volume 15(10) 2009 (22)
Intra-operative assessment of human pulmonary alveoli in vivo using Sidestream Dark Field imaging: a feasibility study ... Intra-operative assessment of human pulmonary alveoli in vivo using Sidestream Dark Field imaging: a feasibility study ...
https://medscimonit.com/archives/issue/idIssue/834882
Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)
Categories: Pulmonary Alveoli Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted ...
https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Pulmonary+Alveoli&parentid=15622&catid=21679
CDC - DPDx - Intestinal HookwormCDC - DPDx - Intestinal Hookworm
They penetrate into the pulmonary alveoli, ascend the bronchial tree to the pharynx, and are swallowed . The larvae reach the ... may be observed may occur during larval pulmonary migration A second urticarial rash may subsequently develop during pulmonary ...
https://www.cdc.gov/dpdx/hookworm/index.html
Journal of Postgraduate Medicine: Table of contentJournal of Postgraduate Medicine: Table of content
Idiopathic pulmonary hemosiderosis: Alveoli are an answer to anemia. p. 57. S Bhatia, MS Tullu, P Vaideeswar, KR Lahiri. DOI: ... Idiopathic pulmonary hemosiderosis (IPH) is a rare disorder (triad of iron-deficiency anemia, hemoptysis, and alveolar ... Lung biopsy diagnosed pulmonary hemosiderosis (interstitial lung disease with hemosiderin-laden macrophages scattered in the ... alveoli and areas of fibrosis in the alveolar septa). The patient showed marked clinical improvement in 10 days of therapy with ...
https://www.jpgmonline.com/showbackIssue.asp?issn=0022-3859
MeSH BrowserMeSH Browser
Pulmonary Alveoli (1988-2009). Respiratory Mucosa (2002-2009). Respiratory System (1988-2009). Public MeSH Note. 2010. History ...
https://meshb.nlm.nih.gov/record/ui?ui=D056151
Registration Dossier - ECHARegistration Dossier - ECHA
The number of macrophages in the pulmonary alveoli increased slightly. This increase was small considering the high (500 mg/nr ... The number of macrophages in the pulmonary alveoli increased slightly. This increase was small considering the high (500 mg/nr ... ANOVA and Duncan´s multiple range test: organ weights, pulmonary function, and pulmonary hydroxyproline. Clinical signs:. no ... ANOVA and Duncan´s multiple range test: organ weights, pulmonary function, and pulmonary hydroxyproline. Clinical signs:. no ...
https://www.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/19775/7/6/1
Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case seriesHistopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
Pulmonary Alveoli / pathology * Pulmonary Alveoli / ultrastructure * Respiratory Mucosa / pathology * Respiratory Mucosa / ... The major pulmonary finding was diffuse alveolar damage in the acute or organising phases, with five patients showing focal ... Although other non-pulmonary organs showed susceptibility to infection, their contribution to the pathogenesis of SARS-CoV-2 ... pulmonary microthrombi. Coronavirus-like particles were detected in the respiratory system, kidney, and gastrointestinal tract ...
https://pubmed.ncbi.nlm.nih.gov/32682491/?dopt=Abstract
Free Medical Flashcards about Med Term Chapter 12Free Medical Flashcards about Med Term Chapter 12
pulmonary parenchyma. essential parts of the lung, responsible for respiration; bronchioles and alveoli. ... pulmonary abscess large collection of pus (bacterial infection) in the lungs. pulmonary edema. fluid in the air sacs and ... pulmonary embolism. clot or other material lodges in vessels of the lung. Can cause area of necrotic tissue to form-pulmonary ... Blood backs up in the pulmonary vessels and fluid seeps into the alveoli and bronchioles ...
https://www.studystack.com/flashcard-3001799
Drug-induced pulmonary disease: MedlinePlus Medical EncyclopediaDrug-induced pulmonary disease: MedlinePlus Medical Encyclopedia
Drug-induced pulmonary disease is lung disease brought on by a bad reaction to a medicine. Pulmonary means related to the lungs ... Bleeding into the lung air sacs, called alveoli (alveolar hemorrhage). *Swelling and inflamed tissue in the main passages that ... Drug-induced pulmonary disease is lung disease brought on by a bad reaction to a medicine. Pulmonary means related to the lungs ... Drug-induced pulmonary disease. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadels Textbook of Respiratory ...
https://medlineplus.gov/ency/article/000104.htm
Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography | Nature...Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography | Nature...
In the 3D high-resolution VOI, the fine mesh of pulmonary blood vessels and the complex network of pulmonary alveoli and their ... infiltration of loose connective tissue and fluid into the alveoli leaves only tiny unconnected portions of the alveoli and the ... Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in COVID-19. N. Engl. J. Med. 383, 120-128 (2020). ... 4c, top). These images show the loss of overall surface area in the lung and smaller and less uniformly shaped alveoli. To ...
https://www.nature.com/articles/s41592-021-01317-x?error=cookies_not_supported
Therapeutic potential of all-trans retinoic acid to attenuate pulmonary hypoplasia in an experimental rat model of congenital...
Pulmonary Alveoli, Alveolar Epithelial Cells, Pulmonary Surfactants, Retinoids, Fibroblasts, +drug effects, Thy-1 Antigens, ... Therapeutic potential of all-trans retinoic acid to attenuate pulmonary hypoplasia in an experimental rat model of congenital ... Friedmacher, F. M. (2019). Therapeutic potential of all-trans retinoic acid to attenuate pulmonary hypoplasia in an ... Therapeutic potential of all-trans retinoic acid to attenuate pulmonary hypoplasia in an experimental rat model of congenital ...
https://researchportal.helsinki.fi/en/publications/therapeutic-potential-of-all-trans-retinoic-acid-to-attenuate-pul
The voice phenomenon - AUSTATThe voice phenomenon - AUSTAT
... the pulmonary alveoli always keep a fraction of air inside. This is called residual volume and prevents the pulmonary alveoli ... You just tested the expansion of your pulmonary alveoli inside of your lungs. This is called inspiratory reserve volume, a ... Here you experienced the expiratory reserve volume, which is the potential for contraction that your pulmonary alveoli has ...
https://www.austat.org.au/2017/05/10/the-voice-phenomenon/
Author: Maegan Wagner, BSN, RN, CCM | Page 2 | NurseTogetherAuthor: Maegan Wagner, BSN, RN, CCM | Page 2 | NurseTogether
Hypoxemic respiratory failure is the inadequate exchange of oxygen between the pulmonary capillaries and the alveoli. The ... decreased pulmonary compliance, and hypoxemia. ARDS often develops after another illness or injury such as sepsis, multiple ...
https://www.nursetogether.com/author/maegan/page/2/
NIOSHTIC-2 Search Results - Full View
Collagenous fibers were also noted in the alveoli, bronchi, and smooth pulmonary blood vessels after 12 months. The collagen ...
http://www2a.cdc.gov/nioshtic-2/BuildQyr.asp?s1=vermiculite&f1=%2A&Startyear=&Adv=0&terms=1&EndYear=&Limit=10000&sort=&D1=10&PageNo=3&RecNo=23&View=f&
2014 ICD-9-CM Diagnosis Codes 492.* : Emphysema2014 ICD-9-CM Diagnosis Codes 492.* : Emphysema
Pulmonary emphysema is a disorder affecting the alveoli (tiny air sacs) of the lungs. The transfer of oxygen and carbon dioxide ... Emphysema is a type of chronic obstructive pulmonary disease (copd) involving damage to the air sacs (alveoli) in the lungs. As ... It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in ... It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in ...
http://www.icd9data.com/2014/Volume1/460-519/490-496/492/default.htm
Alveolus Bio Joins Microbiome Therapeutics Innovation GroupAlveolus Bio Joins Microbiome Therapeutics Innovation Group
PRNewswire/ -- The Microbiome Therapeutics Innovation Group (MTIG) announced today the addition of Alveolus Bio to its ... Chronic Obstructive Pulmonary Disease (COPD), Idiopathic Pulmonary Fibrosis (IPF), and Pulmonary Arterial Hypertension (PAH). ... About Alveolus Bio: Alveolus Bio is a team of scientists, physicians, and innovators pioneering breakthrough FDA-approved ... Alveolus Bio is focused on lung diseases of adulthood, childhood, and infancy. Specifically, Alveolus Bios drug development ...
https://www.prnewswire.com/news-releases/alveolus-bio-joins-microbiome-therapeutics-innovation-group-301418986.html?tc=eml_cleartime
Results Page 9 Arterial blood gas | CramResults Page 9 Arterial blood gas | Cram
The transport of O2 involves the transfer from the alveoli to the pulmonary… ...
https://www.cram.com/subjects/arterial-blood-gas/9
You searched for alveolus - Biology Articles, Tutorials & Dictionary OnlineYou searched for alveolus - Biology Articles, Tutorials & Dictionary Online
Alveolus. Definition noun, plural: alveoli (1) pulmonary alveolus; air sac (2) (general) A concave cavity or pit alveolar,... ... Pulmonary venule. Definition noun, plural: pulmonary venules The venule surrounding the alveolus of the lung and carries oxygen ... Definition noun, plural: alveolar cells The cell lining the pulmonary alveolus; the cell of the air sac of the... Read More ... Organization of the Respiratory System Each lung is composed of air sacs called alveoli - the sites of gas exchange with... ...
https://www.biologyonline.com/search/alveolus
ATSDR - Asbestos Expert Panel - Appendix EATSDR - Asbestos Expert Panel - Appendix E
Particles or fibers depositing in the deep lung respiratory bronchioles or pulmonary alveoli will first contact the aqueous " ... Pulmonary and pleural fiber burdens were normalized to Day 5 data with areas under the curve equal to 100 on Day 5. ... Pulmonary effects of exposure to fine fiberglass: Irregular opacities and small airways obstruction. Br J Ind Med 1992;49:714- ... Pulmonary effects of exposure to fine fiberglass: Irregular opacities and small airways obstruction. Br J Ind Med 1993;50:381- ...
https://www.atsdr.cdc.gov/hac/asbestospanel/appendix_e.html
LungsSacs called alveoliFibrosisCOPDAcuteArteryAirwaysEmphysemaPneumoniaCapillariesEdemaLung DiseasesPathophysiologySurfactantAdjacent alveolusBronchiAirwayAtelectasisHypertensionOedemaAlveolar wallDestruction of their wallsFocalDiseaseOxygenCapillaryChestAsthma2018Distal lungRespiratory bronchiolesObesityPhysiologyBloodAcinusOccurMicrobiomeInfectionDiaphragmPatientsCirculation
Lungs18
  • Pulmonary means related to the lungs. (medlineplus.gov)
  • As Thy-1-/- knockout animals show a phenotype similar to PH in human CDH with impaired alveolar development and reduced proliferation of LIFs, the first objective of this study was to identify disruptions in Thy-1 signaling in hypoplastic rat lungs with toxicological induced CDH, which may have an adverse effect on the expression and lipid content of pulmonary LIFs. (helsinki.fi)
  • This study revealed that disruption of the Thy-1/Adrp signaling cascade in hypoplastic rat lungs leads to a reduction of pulmonary LIFs with significantly fewer cytoplasmatic lipid inclusions and impaired alveolar mesenchymal cell differentiation, which may contribute to decreased alveolar development and PH in the nitrofen-induced CDH model. (helsinki.fi)
  • Emphysema is a type of chronic obstructive pulmonary disease (copd) involving damage to the air sacs (alveoli) in the lungs. (icd9data.com)
  • Pulmonary emphysema is a disorder affecting the alveoli (tiny air sacs) of the lungs. (icd9data.com)
  • The transfer of oxygen and carbon dioxide in the lungs takes place in the walls of the alveoli. (icd9data.com)
  • Pulmonary edema is a condition caused by too much fluid in the lungs. (mayoclinic.org)
  • Therefore, for air to be moved into or out of the lungs, a pressure difference between the atmosphere and the alveoli must be established. (mhmedical.com)
  • As soon as a pressure difference sufficient to overcome the resistance to airflow offered by the conducting airways is established between the atmosphere and the alveoli, air flows into the lungs. (mhmedical.com)
  • Pulmonary oedema is a condition caused by excess fluid in the lungs. (lynchspharmacy.com)
  • Your lungs contain numerous small, elastic air sacs called alveoli. (lynchspharmacy.com)
  • A number of things can cause fluid to accumulate in your lungs, but most have to do with your heart (cardiac pulmonary edema). (lynchspharmacy.com)
  • Normally, deoxygenated blood from all over your body enters the right atrium and flows into the right ventricle, where it's pumped through large blood vessels (pulmonary arteries) to your lungs. (lynchspharmacy.com)
  • Cardiac pulmonary oedema - also known as congestive heart failure - occurs when the diseased or overworked left ventricle isn't able to pump out enough of the blood it receives from your lungs. (lynchspharmacy.com)
  • As the volume of blood in the lungs increases, the pulmonary capillary pressure increases, and if this rises above a value approximately equal to the colloid osmotic pressure of the plasma, about 28 mm Hg, fluid begins to filter out of the capillaries into the lung inter-stitial spaces and alveoli, resulting in pulmonary edema. (brainkart.com)
  • Thus, a Pulmonary function test is done to determine the risk of smoking on the health of your lungs. (mfine.co)
  • The alveoli are where the lungs and the blood exchange oxygen and carbon dioxide during the process of breathing in and breathing out. (kembrel.com)
  • Alveoli (air sacs) are forming in lungs. (wikidoc.org)
Sacs called alveoli3
  • Organization of the Respiratory System Each lung is composed of air sacs called alveoli - the sites of gas exchange with. (biologyonline.com)
  • The bronchioles deliver air to tiny sacs called alveoli where oxygen and carbon dioxide are exchanged. (kembrel.com)
  • The smallest of those branches are called bronchioles, and they end in tiny air sacs called alveoli. (kembrel.com)
Fibrosis6
  • Some drug-induced lung diseases, such as pulmonary fibrosis, may never go away and can worsen, even after the medicine or substance is stopped and can lead to severe lung disease and death. (medlineplus.gov)
  • Specifically, Alveolus Bio's drug development pipeline includes breakthrough therapeutics for respiratory indications such as Chronic Obstructive Pulmonary Disease (COPD), Bronchopulmonary Dysplasia (BPD), and Idiopathic Pulmonary Fibrosis (IPF), as well as a discovery program for Pulmonary Arterial Hypertension (PAH). (prnewswire.com)
  • Their clinical pipeline includes preclinical phase live biotherapeutics for Bronchopulmonary Dysplasia (BPD), Chronic Obstructive Pulmonary Disease (COPD), Idiopathic Pulmonary Fibrosis (IPF), and Pulmonary Arterial Hypertension (PAH). (prnewswire.com)
  • The illnesses include bronchial asthma, chronic obstructive pulmonary diseases (COPD), pulmonary fibrosis, pulmonary emphysema (hyperinflation of pulmonary alveoli) and pulmonary oedema. (beurer.com)
  • Two patients had a CT pattern of pulmonary fibrosis indistinguishable from idiopathic pulmonary fibrosis. (lww.com)
  • Emphysema is characterized by decreased gas exchange and the abnormal permanent enlargement of the alveoli, along with destruction of their walls and without obvious fibrosis (emphysematous alveoli). (doereport.com)
COPD7
  • Patients with MAT frequently have significant comorbidities, especially chronic obstructive pulmonary disease (COPD) and respiratory failure, and are often treated in ICUs. (medscape.com)
  • A subcategory of chronic obstructive pulmonary disease (copd). (icd9data.com)
  • While cigarette smoking is associated with the development of chronic obstructive pulmonary diseases (COPD) and lung cancer, in utero exposures to CS and second-hand smoke (SHS) are associated with asthma development in the offspring. (frontiersin.org)
  • Chronic obstructive pulmonary diseases (COPD), asthma, and lung cancer are leading public health care burdens for which therapeutic options are currently limited. (frontiersin.org)
  • This set of medical illustrations depicts chronic obstructive pulmonary disease (COPD), also known as chronic obstructive airway disease (COAD). (doereport.com)
  • The smoke damages your airways and the small air sacs(alveoli) leading to diseases such as COPD, emphysema, and bronchitis. (mfine.co)
  • Chronic obstructive pulmonary disease (COPD) is a progressing disease, with lung but not gut microbiota implicated in its etiology. (cdc.gov)
Acute8
  • The major pulmonary finding was diffuse alveolar damage in the acute or organising phases, with five patients showing focal pulmonary microthrombi. (nih.gov)
  • Acute respiratory distress syndrome (ARDS) is a progressive form of acute respiratory failure characterized by dyspnea, decreased pulmonary compliance, and hypoxemia. (nursetogether.com)
  • Severe infections in neonatal pups can result in acute death at a few days of age as large numbers of larvae that were acquired in utero cross the alveoli en route to the small intestine. (capcvet.org)
  • Pulmonary edema that develops suddenly (acute pulmonary edema) is a medical emergency that needs immediate care. (mayoclinic.org)
  • Pulmonary edema that comes on suddenly (acute pulmonary edema) is life-threatening. (mayoclinic.org)
  • In severe, acute left heart failure,pulmonary edema occasionally occurs so rapidly that it can cause death by suffocation in 20 to 30 minutes. (brainkart.com)
  • Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are commonly encountered in the primary care setting, though the accurate and timely diagnosis is problematic. (cdc.gov)
  • One potential explanation for acute lipoid pneumonia among these patients is that aerosolized oils inhaled from e-cigarettes deposited within their distal airways and alveoli, inciting a local inflammatory response that impaired vital gas exchange. (cdc.gov)
Artery4
  • Stroke volume, diastolic blood pressure and pulmonary artery end diastolic pressure remained unchanged. (nih.gov)
  • The oxygen-rich blood then returns to the left atrium through the pulmonary veins, flows through the mitral valve into the left ventricle, and finally leaves your heart through another large artery, the aorta. (lynchspharmacy.com)
  • Congestive heart failure can also occur when the right ventricle is unable to overcome increased pressure in the pulmonary artery, which usually results from left heart failure, chronic lung disease or high blood pressure in the pulmonary artery (pulmonary hypertension). (lynchspharmacy.com)
  • right extremity which result in pulmonary artery, into two efferent ve«s«l of the synovial membranes. (wildwoodclinic.com)
Airways3
  • This also accounts for the fact that longer fibers have proportionately more deposition in the airways as opposed to peripheral alveoli. (cdc.gov)
  • Thus, young children depend more on the feeding airways to move air into the alveoli. (medscape.com)
  • Extrinsic compression on the airways is most likely to come from enlarged lymph nodes (such as those due to tuberculosis infection), lymphoma and other tumors in the chest, an enlarged heart that compresses the left main or left lower lobe bronchus, and left-to-right intracardiac shunts that increase blood flow through the pulmonary arteries. (medscape.com)
Emphysema2
  • Pulmonary emphysema can be classified by the location and distribution of the lesions. (icd9data.com)
  • In emphysema, the alveoli become abnormally inflated, damaging their walls and making it harder to breathe. (icd9data.com)
Pneumonia1
  • Other clinical manifestations of hookworm infection include an urticarial dermal reaction ("ground itch") associated with filariform (L3) larvae penetration, and respiratory involvement including eosinophilic pneumonia may be observed may occur during larval pulmonary migration A second urticarial rash may subsequently develop during pulmonary migration. (cdc.gov)
Capillaries3
  • Hypoxemic respiratory failure is the inadequate exchange of oxygen between the pulmonary capillaries and the alveoli. (nursetogether.com)
  • As a result, pressure increases inside the left atrium and then in the pulmonary veins and capillaries, causing fluid to be pushed through the capillary walls into the air sacs. (lynchspharmacy.com)
  • Something has blocked an airway and the distal lung collapses as all gas in the blocked alveoli is sucked up into the capillaries. (derangedphysiology.com)
Edema13
  • This diastolic dysfunction raises the pressure gradient of blood in the pulmonary vessels, which causes fluid or transudate to leak from these vessels into the lung alveoli, causing pulmonary edema. (news-medical.net)
  • In most cases, heart problems cause pulmonary edema. (mayoclinic.org)
  • Pulmonary edema can sometimes cause death. (mayoclinic.org)
  • Treatment for pulmonary edema depends on the cause but generally includes additional oxygen and medications. (mayoclinic.org)
  • Pulmonary edema symptoms may appear suddenly or develop over time. (mayoclinic.org)
  • Symptoms depend on the type of pulmonary edema. (mayoclinic.org)
  • Symptoms of high-altitude pulmonary edema (HAPE) tend to get worse at night. (mayoclinic.org)
  • The causes of pulmonary edema vary. (mayoclinic.org)
  • Pulmonary edema falls into two categories, depending on where the problem starts. (mayoclinic.org)
  • If a heart problem causes the pulmonary edema, it's called cardiogenic pulmonary edema. (mayoclinic.org)
  • If pulmonary edema is not heart related, it's called noncardiogenic pulmonary edema. (mayoclinic.org)
  • Depending on the cause, pulmonary edema symptoms may appear suddenly or develop slowly. (lynchspharmacy.com)
  • Thus, among the most important problems of left heart failure are pulmonary vascular congestion and pulmonary edema . (brainkart.com)
Lung Diseases3
  • Founded and managed by physician scientists based on 15+ years of research into neutrophilic inflammation and microbial dysbiosis associated with chronic pulmonary disease, Alveolus Bio is focused on lung diseases of adulthood, childhood, and infancy. (prnewswire.com)
  • Alveolus' pipeline of breakthrough therapeutics for lung diseases underscores the potential of microbiome therapeutics to treat a wide range of indications. (prnewswire.com)
  • Alveolus Bio is a team of scientists, physicians, and innovators pioneering breakthrough FDA-approved therapeutics for lung diseases. (prnewswire.com)
Pathophysiology1
  • In this review we highlight the overall pulmonary pathophysiology of COVID-19, and provide an overview of animal models well-suited for mechanistic studies and preclinical therapeutic trials. (ersjournals.com)
Surfactant4
  • Her current research examines pulmonary surfactant, the complex protein-lipid substance lining the alveoli. (grahamfoundation.org)
  • States the roles of pulmonary surfactant and alveolar interdependence in the recoil and expansion of the lung. (mhmedical.com)
  • My guess is that some but not a lot of surfactant administered via nebulization reaches the alveoli. (allthingsneonatal.com)
  • The alveoli collapse in the absence of surfactant. (derangedphysiology.com)
Adjacent alveolus2
  • Model of an adjacent alveolus: enlarged approx. (southernbiological.com)
  • Modeling alveolar wall thickening by encircling the tumor with thickened walls moved the strain amplification radially outward, to the next adjacent alveolus. (bvsalud.org)
Bronchi2
  • Collagenous fibers were also noted in the alveoli, bronchi, and smooth pulmonary blood vessels after 12 months. (cdc.gov)
  • The terminal bronchi and alveoli are located at the very end of the conducting zone and the beginning of the respiratory zone in the respiratory system. (kembrel.com)
Airway2
  • The ending of a tiny airway in the lung, where the alveoli (air sacs) are located. (medicinenet.com)
  • The terminal bronchiole is the smallest conducting airway without alveoli in its walls. (kembrel.com)
Atelectasis1
Hypertension2
  • Many factors previously reported to be associated with mortality in smaller studies were not confirmed, such as obesity, Black race, Hispanic ethnicity, chronic obstructive pulmonary disease, hypertension, and smoking. (cdc.gov)
  • In this review and meta-analysis, we found that elderly male patients with a high body mass index, high breathing rate and a combination of underlying diseases (such as hypertension, diabetes, cardiovascular disease, and chronic obstructive pulmonary disease) were more likely to become critically ill. (cdc.gov)
Oedema3
  • Although pulmonary oedema can sometimes prove fatal, the outlook may be good when you receive prompt treatment for pulmonary oedema along with treatment for the underlying problem. (lynchspharmacy.com)
  • Pulmonary oedema can be fatal if not treated. (lynchspharmacy.com)
  • Rapid weight gain when pulmonary oedema develops as a result of congestive heart failure, a condition in which your heart pumps too little blood to meet your body's needs. (lynchspharmacy.com)
Alveolar wall1
  • It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in difficulty breathing. (icd9data.com)
Destruction of their walls1
  • A condition of the lung characterized by increase beyond normal in the size of air spaces distal to the terminal bronchioles, either from dilatation of the alveoli or from destruction of their walls. (icd9data.com)
Focal1
  • Submicroscopic changes of pulmonary alveoli were represented by focal thickening of the basement membrane, multiple foci of hyperplastic type II cell (the precondition of the alveologenic tumor), active discharge of osmiophilic lamellar bodies from the type II cell and phagocytosis of the bodies by macrophages, appearance of cholesterol crystalloids in the macrophages, degeneration of alveolar septal cells and occasional appearance of a large nucleus with swelling of the capillary endothelium. (cdc.gov)
Disease4
  • Drug-induced pulmonary disease is lung disease brought on by a bad reaction to a medicine. (medlineplus.gov)
  • In addition, risk for dissemination or progressive pulmonary disease is higher in certain groups (eg, those of Oceanic or African genomic ancestry). (medscape.com)
  • Extracellular vesicles released in response to cigarette smoke might trigger chronic obstructive pulmonary disease, but engineered versions could be a treatment. (cdc.gov)
  • Twenty-five states have reported more than 200 possible cases of severe pulmonary disease associated with the use of electronic cigarettes (e-cigarettes). (cdc.gov)
Oxygen5
  • Alveoli are the vital lung structures where the transfer of oxygen and carbon dioxide takes place. (icd9data.com)
  • Definition noun, plural: pulmonary venules The venule surrounding the alveolus of the lung and carries oxygen-rich. (biologyonline.com)
  • The blood does not pick up oxygen from the corresponding alveoli. (medscape.com)
  • But in certain circumstances, the alveoli fill with fluid instead of air, preventing oxygen from being absorbed into your bloodstream. (lynchspharmacy.com)
  • The alveoli are where the oxygen is picked up by your blood. (kembrel.com)
Capillary1
  • Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place. (bvsalud.org)
Chest1
  • The occurrence of the nonneoplastic pulmonary abnormalities among vinyl chloride polymerization workers has been reported on the basis of chest x-ray (18), pulmonary function (19) and smear cytology (1) of the worker's sputum. (cdc.gov)
Asthma1
  • HSAEpC are qualified for functional studies to investigate disorders such as asthma or pulmonary inflammation. (promocell.com)
20181
  • estudio transversal, con datos de 361 registros médicos de pacientes que participaron en el proyecto de 2014 a 2018. (bvsalud.org)
Distal lung1
  • Although the lung has extensive regenerative capacity, some diseases affecting the distal lung result in irreversible loss of pulmonary alveoli. (bvsalud.org)
Respiratory bronchioles2
  • The distal respiratory tract mainly consists of pulmonary alveoli, which are spherical outcroppings of the respiratory bronchioles and are the primary sites of gas exchange with the blood. (promocell.com)
  • Terminal bronchioles become respiratory bronchioles when cilia start to disappear and alveoli start to bud off. (kembrel.com)
Obesity1
  • The effect of other factors on pulmonary function, including obesity, breastfeeding and parental atopy, was also examined. (who.int)
Physiology1
  • Pulmonary Physiology, 8e Levitzky MG. Levitzky M.G.(Ed.), Ed. Michael G. Levitzky. (mhmedical.com)
Blood2
  • The breath test is an indirect test, but has been considered to be a good estimate of the BAC because of the assumption that an end-exhaled breath sample accurately reflects the alveolar (or deep lung) air alcohol concentration which is thought to be in equilibrium with the blood in the pulmonary circulation. (blogspot.com)
  • As a result, the mean pulmonary filling pressure rises because of shift of large volumes of blood from the sys-temic circulation into the pulmonary circulation. (brainkart.com)
Acinus1
  • The pulmonary acinus is the gas exchange unit in the lung and has a very complex microstructure. (bvsalud.org)
Occur1
  • Transmission is most likely to occur from patients who have unrecognized pulmonary or laryngeal TB, are not on effective anti-TB therapy, and have not been placed in TB isolation. (cdc.gov)
Microbiome3
  • WASHINGTON , Nov. 9, 2021 /PRNewswire/ -- The Microbiome Therapeutics Innovation Group (MTIG) announced today the addition of Alveolus Bio to its coalition of companies leading the research and development of FDA-approved microbiome therapeutic drugs and microbiome-based products. (prnewswire.com)
  • Dr. Lal and the Alveolus team will be a strong asset in our coalition's advocacy efforts to advance the regulatory field for emerging microbiome therapeutics. (prnewswire.com)
  • Alveolus Bio's membership reflects MTIG's commitment to building a strong and diverse coalition of companies driving innovation in the microbiome space, and supporting safe, well-researched technologies for patient benefit. (prnewswire.com)
Infection1
  • Although other non-pulmonary organs showed susceptibility to infection, their contribution to the pathogenesis of SARS-CoV-2 infection requires further examination. (nih.gov)
Diaphragm1
  • Congenital diaphragmatic hernia (CDH) is a prenatal defect in the integrity of the developing diaphragm, which results in pulmonary hypoplasia (PH) with alveolar immaturity. (helsinki.fi)
Patients1
  • provide a rigorous summary of the available evidence on pulmonary histopathological findings in patients with COVID-19. (bvsalud.org)
Circulation1
  • Very little, if any, alcohol originates from the pulmonary circulation surrounding the alveoli. (blogspot.com)
Suchen nach Schlagwort Pulmonary Alveoli
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Drowning: Background, Etiology, Epidemiology
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IJMS | Free Full-Text | Graphene Nanomaterials: Synthesis, Biocompatibility, and Cytotoxicity
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Atrial Tachycardia Treatment & Management: Approach Considerations, Cardioversion, Pharmacologic Treatment
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Atrial Tachycardia Treatment & Management: Approach Considerations, Cardioversion, Pharmacologic Treatment
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CDC - DPDx - Intestinal Hookworm
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CDC - Zoonotic Hookworm - Biology
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A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease - Study...
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Figure 1 - Weissella confusa Infection in Primate (Cercopithecus mona) - Volume 9, Number 10-October 2003 - Emerging Infectious...
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(emedicine.medscape.com)
Cardiogenic Pulmonary Edema Treatment & Management: Approach Considerations, Ventilatory Support, Preload Reduction
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Mechanical Ventilation: Background, Classifications of Positive-Pressure Ventilators, Indications for Mechanical Ventilation
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MeSH Browser
MeSH Browser (meshb.nlm.nih.gov)
Figure - Emergence of African Swine Fever Virus, Northwestern Iran - Volume 16, Number 12-December 2010 - Emerging Infectious...
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Pulmonary Function Testing: Spirometry, Lung Volume Determination, Diffusing Capacity of Lung for Carbon Monoxide
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