A period in the human life in which the development of the hypothalamic-pituitary-gonadal system takes place and reaches full maturity. The onset of synchronized endocrine events in puberty lead to the capacity for reproduction (FERTILITY), development of secondary SEX CHARACTERISTICS, and other changes seen in ADOLESCENT DEVELOPMENT.
Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.
The lack of development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations above the mean age at onset of PUBERTY in a population. Delayed puberty can be classified by defects in the hypothalamic LHRH pulse generator, the PITUITARY GLAND, or the GONADS. These patients will undergo spontaneous but delayed puberty whereas patients with SEXUAL INFANTILISM will not.
Achievement of full sexual capacity in animals and in humans.
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Intercellular signaling peptides that were originally characterized by their ability to suppress NEOPLASM METASTASIS. Kisspeptins have since been found to play an important role in the neuroendocrine regulation of REPRODUCTION.
Establishment of the age of an individual by examination of their skeletal structure.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
The total process by which organisms produce offspring. (Stedman, 25th ed)
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.
Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.
Gradual increase in the number, the size, and the complexity of cells of an individual. Growth generally results in increase in ORGAN WEIGHT; BODY WEIGHT; and BODY HEIGHT.
Neoplastic, inflammatory, infectious, and other diseases of the hypothalamus. Clinical manifestations include appetite disorders; AUTONOMIC NERVOUS SYSTEM DISEASES; SLEEP DISORDERS; behavioral symptoms related to dysfunction of the LIMBIC SYSTEM; and neuroendocrine disorders.
The continuous sequential physiological and psychological changes during ADOLESCENCE, approximately between the age of 13 and 18.
Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
The discharge of an OVUM from a rupturing follicle in the OVARY.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
The processes of anatomical and physiological changes related to sexual or reproductive functions during the life span of a human or an animal, from FERTILIZATION to DEATH. These include SEX DETERMINATION PROCESSES; SEX DIFFERENTIATION; SEXUAL MATURATION; and changes during AGING.
A stage of development at which the ADRENAL GLANDS undergo maturation leading to the capability of producing increasing amounts of adrenal androgens, DEHYDROEPIANDROSTERONE and ANDROSTENEDIONE. Adrenarche usually begins at about 7 or 8 years of age before the signs of PUBERTY and continues throughout puberty.
The capacity to conceive or to induce conception. It may refer to either the male or female.
A system of NEURONS that has the specialized function to produce and secrete HORMONES, and that constitutes, in whole or in part, an ENDOCRINE SYSTEM or organ.
Permanent deprivation of breast milk and commencement of nourishment with other food. (From Stedman, 25th ed)
Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.
FIBROUS DYSPLASIA OF BONE affecting several bones. When melanotic pigmentation (CAFE-AU-LAIT SPOTS) and multiple endocrine hyperfunction are additionally associated it is referred to as Albright syndrome.
Hormones produced by the GONADS, including both steroid and peptide hormones. The major steroid hormones include ESTRADIOL and PROGESTERONE from the OVARY, and TESTOSTERONE from the TESTIS. The major peptide hormones include ACTIVINS and INHIBINS.
A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ A with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the URINARY BLADDER and UTERUS.
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Small containers or pellets of a solid drug implanted in the body to achieve sustained release of the drug.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Steroid hormones produced by the GONADS. They stimulate reproductive organs, germ cell maturation, and the secondary sex characteristics in the males and the females. The major sex steroid hormones include ESTRADIOL; PROGESTERONE; and TESTOSTERONE.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE with D-tryptophan substitution at residue 6.
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.
Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR) that stimulate gonadal functions in both males and females. They include FOLLICLE STIMULATING HORMONE that stimulates germ cell maturation (OOGENESIS; SPERMATOGENESIS), and LUTEINIZING HORMONE that stimulates the production of sex steroids (ESTROGENS; PROGESTERONE; ANDROGENS).
The measurement of an organ in volume, mass, or heaviness.
Methods for recognizing the state of ESTRUS.
A cutaneous pouch of skin containing the testicles and spermatic cords.
A small, unpaired gland situated in the SELLA TURCICA. It is connected to the HYPOTHALAMUS by a short stalk which is called the INFUNDIBULUM.
A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.
A synthetic hormone with anabolic and androgenic properties.
Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.
The surgical removal of one or both ovaries.
The period of cyclic physiological and behavior changes in non-primate female mammals that exhibit ESTRUS. The estrous cycle generally consists of 4 or 5 distinct periods corresponding to the endocrine status (PROESTRUS; ESTRUS; METESTRUS; DIESTRUS; and ANESTRUS).
Sexual activities of animals.
MAMMARY GLANDS in the non-human MAMMALS.
The surgical removal of one or both testicles.
Increase in BODY WEIGHT over existing weight.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
The relative amounts of various components in the body, such as percentage of body fat.
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
The production of offspring by selective mating or HYBRIDIZATION, GENETIC in animals or plants.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
The gamete-producing glands, OVARY or TESTIS.
Voluntary acceptance of a child of other parents to be as one's own child, usually with legal confirmation.
Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
An imbalanced NUTRITIONAL STATUS resulting from excessive intake of nutrients. Generally, overnutrition generates an energy imbalance between food consumption and energy expenditure leading to disorders such as OBESITY.
The number of offspring produced at one birth by a viviparous animal.
The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE.
A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesis and release of pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE.
Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.
Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
Steroidal compounds related to PROGESTERONE, the major mammalian progestational hormone. Progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.
Receptors with a 6-kDa protein on the surfaces of cells that secrete LUTEINIZING HORMONE or FOLLICLE STIMULATING HORMONE, usually in the adenohypophysis. LUTEINIZING HORMONE-RELEASING HORMONE binds to these receptors, is endocytosed with the receptor and, in the cell, triggers the release of LUTEINIZING HORMONE or FOLLICLE STIMULATING HORMONE by the cell. These receptors are also found in rat gonads. INHIBINS prevent the binding of GnRH to its receptors.
Development of male secondary SEX CHARACTERISTICS in the FEMALE. It is due to the effects of androgenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.
Congenital conditions in individuals with a male karyotype, in which the development of the gonadal or anatomical sex is atypical.
Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the gonadotropins found in the pregnant mare serum, a rich source of equine CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; and FOLLICLE STIMULATING HORMONE. Unlike that in humans, the equine LUTEINIZING HORMONE, BETA SUBUNIT is identical to the equine choronic gonadotropin, beta. Equine gonadotropins prepared from pregnant mare serum are used in reproductive studies.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.
A class of cell surface receptors for tachykinins that prefers neurokinin B (neurokinin beta, neuromedin K) over other tachykinins. Neurokinin-3 (NK-3) receptors have been cloned and are members of the G-protein coupled receptor superfamily. They have been found in the central nervous system and in peripheral tissues.
Surgical removal or artificial destruction of gonads.
Refers to animals in the period of time just after birth.
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
Elements of limited time intervals, contributing to particular results or situations.
The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH.
Method to determine the occurrence of OVULATION by direct or indirect means. Indirect methods examine the effects of PROGESTERONE on cervical mucus (CERVIX MUCUS), or basal body temperature. Direct ovulation detection, generally used in fertility treatment, involves analyses of circulating hormones in blood and ULTRASONOGRAPHY.
A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
Chemical compounds causing LUTEOLYSIS or degeneration.
The external and internal organs related to reproduction.
A subclass of alpha-amylase ISOENZYMES that are secreted into SALIVA.
An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
A nucleus located in the middle hypothalamus in the most ventral part of the third ventricle near the entrance of the infundibular recess. Its small cells are in close contact with the ependyma.
The process in developing sex- or gender-specific tissue, organ, or function after SEX DETERMINATION PROCESSES have set the sex of the GONADS. Major areas of sex differentiation occur in the reproductive tract (GENITALIA) and the brain.
A condition caused by the excessive secretion of ANDROGENS from the ADRENAL CORTEX; the OVARIES; or the TESTES. The clinical significance in males is negligible. In women, the common manifestations are HIRSUTISM and VIRILISM as seen in patients with POLYCYSTIC OVARY SYNDROME and ADRENOCORTICAL HYPERFUNCTION.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
The female reproductive organs. The external organs include the VULVA; BARTHOLIN'S GLANDS; and CLITORIS. The internal organs include the VAGINA; UTERUS; OVARY; and FALLOPIAN TUBES.
A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Methods and procedures for the diagnosis of diseases or dysfunction of the endocrine glands or demonstration of their physiological processes.
(S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN.
The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
An anti-inflammatory glucocorticoid used in veterinary practice.
The adaptive superiority of the heterozygous GENOTYPE with respect to one or more characters in comparison with the corresponding HOMOZYGOTE.
The science of breeding, feeding and care of domestic animals; includes housing and nutrition.
A genus of diurnal rats in the family Octodonidae, found in South America. The species Octodon degus is frequently used for research.
A genus of hamsters characterized by small size, very short tail, and short, broad feet with hairy soles.
The tendency of a phenomenon to recur at regular intervals; in biological systems, the recurrence of certain activities (including hormonal, cellular, neural) may be annual, seasonal, monthly, daily, or more frequently (ultradian).
The convoluted tubules in the TESTIS where sperm are produced (SPERMATOGENESIS) and conveyed to the RETE TESTIS. Spermatogenic tubules are composed of developing germ cells and the supporting SERTOLI CELLS.
Those protein complexes or molecular sites on the surfaces and cytoplasm of gonadal cells that bind luteinizing or chorionic gonadotropic hormones and thereby cause the gonadal cells to synthesize and secrete sex steroids. The hormone-receptor complex is internalized from the plasma membrane and initiates steroid synthesis.
An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.
Pathological processes of the OVARIES or the TESTES.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Neoplasms which originate from pineal parenchymal cells that tend to enlarge the gland and be locally invasive. The two major forms are pineocytoma and the more malignant pineoblastoma. Pineocytomas have moderate cellularity and tend to form rosette patterns. Pineoblastomas are highly cellular tumors containing small, poorly differentiated cells. These tumors occasionally seed the neuroaxis or cause obstructive HYDROCEPHALUS or Parinaud's syndrome. GERMINOMA; CARCINOMA, EMBRYONAL; GLIOMA; and other neoplasms may arise in the pineal region with germinoma being the most common pineal region tumor. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2064; Adams et al., Principles of Neurology, 6th ed, p670)
The time period of daily exposure that an organism receives from daylight or artificial light. It is believed that photoperiodic responses may affect the control of energy balance and thermoregulation.
Pathological processes of the OVARY.
The series of changes to the shape, size, components, and functions of an individual organism that occur over time as the organism progresses from its initial form to full size and maturity.
A count of SPERM in the ejaculum, expressed as number per milliliter.

Prolactin receptor expression in the developing human prostate and in hyperplastic, dysplastic, and neoplastic lesions. (1/1150)

In situ hybridization and immunohistochemistry were used to localize and compare the expression of the long form of the human prolactin receptor in fetal, prepubertal, and adult prostate. Results were then compared with hyperplastic, dysplastic, and neoplastic lesions. Both receptor message and protein were predominately localized in epithelial cells of the fetal, neonatal, prepubertal, and normal adult prostate. In hyperplastic lesions the expression of the receptor was unchanged with respect to normal epithelial cells. Irrespective of grade, markedly enhanced expression of the receptor was evident in dysplastic lesions. In lower Gleason grade carcinomas the intensity of receptor signal at the message and protein levels approximated that found in normal prostatic epithelium. However, in foci within higher grade cancers, receptor expression appeared diminished. Results from our study suggest that prolactin action plays a role in the development and maintenance of the human prostate and may also participate in early neoplastic transformation of the gland. Diminution of receptor expression in high grade neoplasms could reflect the emergence of a population of cells that are no longer responsive to the peptide hormone.  (+info)

Microalbuminuria prevalence varies with age, sex, and puberty in children with type 1 diabetes followed from diagnosis in a longitudinal study. Oxford Regional Prospective Study Group. (2/1150)

OBJECTIVE: The predictive value of microalbuminuria (MA) in children with type 1 diabetes has not been defined. We describe the natural history of MA in a large cohort of children recruited at diagnosis of type 1 diabetes. RESEARCH DESIGN AND METHODS: Between 1985 and 1996, 514 children (279 male) who developed type 1 diabetes before the age of 16 years (91% of those eligible from a region where ascertainment of new cases is 95%) were recruited for a longitudinal study with central annual assessment of HbAlc and albumin excretion (three urine samples). Dropout rates have been < 1% per year, and 287 children have been followed for > 4.5 years. RESULTS: MA (defined as albumin-to-creatinine ratio > or = 3.5 and > or = 4.0 mg/mmol in boys and girls, respectively) developed in 63 (12.8%) and was persistent in 22 (4.8%) of the subjects. The cumulative probability (based on the Kaplan-Meier method) for developing MA was 40% after 11 years. HbAlc was worse in those who developed MA than in others (mean difference +/- SEM: 1.1% +/- 0.2, P < 0.001). In subjects who had been 5-11 years of age when their diabetes was diagnosed, the appearance of MA was delayed until puberty, whereas of those whose age was < 5 years at diagnosis of diabetes, 5 of 11 (45%) developed MA before puberty. The adjusted proportional probability (Cox model) of MA was greater for female subjects (200%), after pubertal onset (310%), and with greater HbAlc (36% increase for every 1% increase in HbAlc). Despite earlier differences based on age at diagnosis of diabetes (< 5, 5-11, and > 11 years), the overall cumulative risks in these groups were similar (38 vs. 29 vs. 39%, respectively) after 10 years' duration of diabetes. CONCLUSIONS: Prepubertal duration of diabetes and prepubertal hyperglycemia contribute to the risk of postpubertal MA. The differences in rates of development of MA relating to HbAlc, sex, and age at diagnosis relative to puberty may have long-term consequences for the risk of subsequent nephropathy and for cardiovascular risk.  (+info)

Pelvic ultrasonography in Turner syndrome: standards for uterine and ovarian volume. (3/1150)

The purpose of this study was to investigate uterine and ovarian size according to age and pubertal stage in patients with Turner syndrome. Ultrasonographic evaluation of the uterus and the ovaries was performed in 93 patients with Turner syndrome, aged 12 days to 17.85 years. The data were compared with those of 190 healthy controls. One or both ovaries were detected in 41 of 93 patients (44%). Within the prepubertal group, mean uterine volume and mean ovarian volume of the patients with Turner syndrome were significantly (P<0.001) lower than those of controls (0.5+/-0.2 ml versus 1.0+/-0.3 ml; 0.3+/-0.3 ml versus 0.6+/-0.4 ml, respectively). In prepubertal girls, no significant relationship was found between age and uterine size or ovarian size. Both uterine volume and ovarian volume of 19 women with spontaneous puberty increased during breast development, although mean uterine volume and mean ovarian volume were significantly (P<0.01) lower than those of pubertal control patients.  (+info)

Randomised controlled trial of recombinant human growth hormone in prepubertal and pubertal renal transplant recipients. British Association for Pediatric Nephrology. (4/1150)

AIMS: To evaluate the efficacy (height velocity (HV), change in height standard deviation score (delta HSDS)), and safety (glomerular filtration rate (GFR), incidence of rejection, and calcium and glucose metabolism) of recombinant human growth hormone (rhGH) treatment after renal transplantation. DESIGN: A two year randomised controlled trial. SUBJECTS: Fifteen prepubertal and seven pubertal children: mean (SD) age, 13.0 (2.6) and 15.2 (2.4) years, respectively; mean (SD) GFR, 51 (30) and 48 (17) ml/min/1.73 m2, respectively. Six prepubertal and three pubertal children were controls during the first year; all received rhGH in the second year. RESULTS: In the first year, mean (SE) HV and delta HSDS in the prepubertal treated group increased compared with controls: 8.1 (0.9) v 3.7 (0.6) cm/year and 0.6 (0.1) v -0.3 (0.2), respectively. In the pubertal treated group, mean (SE) HV and delta HSDS were also greater: 10.1 (0.6) v 3.9 (1.3) cm/year and 0.6 (0.1) v -0.1 (0.2), respectively. Comparing all treated and control children, there was no significant change in GFR: treated group, mean (SE) 9.9 (5.4) ml/min/1.73 m2 v control group, -1.6 (7.6) ml/min/1.73 m2. There were also no differences in the incidence of rejection in the first year: eight episodes in 13 patients v five episodes in nine patients, respectively. Phosphate, alkaline phosphatase (ALP), parathyroid hormone (PTH), and fasting insulin concentrations rose during the first year of treatment, but not thereafter. In the second year of treatment, HV remained above baseline. CONCLUSION: Treatment with rhGH improves growth in prepubertal and pubertal children with renal transplants, with no significant change in GFR or the incidence of rejection. Phosphate, ALP, PTH, and insulin increased during the first year of treatment.  (+info)

Serum galactosyl hydroxylysine as a biochemical marker of bone resorption. (5/1150)

BACKGROUND: Serum-based biochemical markers of bone resorption may provide better clinical information than urinary markers because direct comparison with serum markers of bone formation is possible and because the within-subject variability of serum markers may be lower. We describe a method for the measurement of free beta-1-galactosyl-O-hydroxylysine (Gal-Hyl) in serum. METHODS: The assay used preliminary ultrafiltration of serum, dansylation, and separation by reversed-phase HPLC with fluorescence detection. Healthy subjects were recruited from population-based studies of bone turnover. RESULTS: The within-run (n = 15) and between-run (n = 15) CVs were 7% and 14%, respectively, at a mean value of 48 nmol/L. In women and pubertal girls, serum free Gal-Hyl correlated with urine free Gal-Hyl (r = 0.84; P <0.001). Serum Gal-Hyl was higher during puberty and increased after menopause. The fractional renal clearance of free Gal-Hyl relative to that of creatinine was 0.90 (95% confidence interval, 0.82-0.98). Serum free Gal-Hyl decreased by 36% (SE = 4%) in 14 patients with mild Paget disease treated with an oral bisphosphonate, and this decrease was significantly (P <0. 001) greater than that seen for either serum tartrate-resistant acid phosphatase (9%; SE = 4%) or serum C-terminal telopeptide of collagen I (19%; SE = 8%). CONCLUSION: Serum free Gal-Hyl may be useful as a serum marker of bone resorption.  (+info)

Whole-body protein turnover and resting energy expenditure in obese, prepubertal children. (6/1150)

BACKGROUND: Obesity is becoming more frequent in children; understanding the extent to which this condition affects not only carbohydrate and lipid metabolism but also protein metabolism is of paramount importance. OBJECTIVE: We evaluated the kinetics of protein metabolism in obese, prepubertal children in the static phase of obesity. DESIGN: In this cross-sectional study, 9 obese children (x +/- SE: 44+/-4 kg, 30.9+/-1.5% body fat) were compared with 8 lean (28+/-2 kg ,16.8+/-1.2% body fat), age-matched (8.5+/-0.2 y) control children. Whole-body nitrogen flux, protein synthesis, and protein breakdown were calculated postprandially over 9 h from 15N abundance in urinary ammonia by using a single oral dose of [15N]glycine; resting energy expenditure (REE) was assessed by indirect calorimetry (canopy) and body composition by multiple skinfold-thickness measurements. RESULTS: Absolute rates of protein synthesis and breakdown were significantly greater in obese children than in control children (x +/- SE: 208+/-24 compared with 137+/-14 g/d, P < 0.05, and 149+/-20 compared with 89+/-13 g/d, P < 0.05, respectively). When these variables were adjusted for fat-free mass by analysis of covariance, however, the differences between groups disappeared. There was a significant relation between protein synthesis and fat-free mass (r = 0.83, P < 0.001) as well as between protein synthesis and REE (r = 0.79, P < 0.005). CONCLUSIONS: Obesity in prepubertal children is associated with an absolute increase in whole-body protein turnover that is consistent with an absolute increase in fat-free mass, both of which contribute to explaining the greater absolute REE in obese children than in control children.  (+info)

Plasma homocysteine concentration in a Belgian school-age population. (7/1150)

BACKGROUND: Total plasma homocysteine (tHcy) is an independent risk factor for cardiovascular disease in adults. Data for children and adolescents are lacking. OBJECTIVE: The aim of this study was to provide a reference range for tHcy and to explore the relation between tHcy and nutritional indexes in a Belgian pediatric population. DESIGN: tHcy, folate, and vitamin B-12 were measured in 647 healthy children (353 girls and 294 boys) aged 5-19 y. RESULTS: The tHcy distribution was, as in adults, skewed to the right [geometric mean (-1 SD, +1 SD): 7.41 micromol/L (5.51, 9.96)]. Concentrations were lowest in younger children and increased with age. After the tHcy distribution was examined according to age, 3 age ranges were distinguished: 5-9 y [6.21 micromol/L (5.14, 7.50)], 10-14 y [7.09 micromol/L (5.69, 8.84)], and 15-19 y [8.84 micromol/L (6.36, 12.29)]. We observed no significant differences in tHcy values between girls and boys in children aged < 15 y; in postpubertal children, however, concentrations were higher in boys than in girls. In the 3 age groups, folate was inversely correlated with tHcy; the negative relation between tHcy and vitamin B-12 was less strong. Familial cardiovascular disease was more frequent in children who had hyperhomocysteinemia. CONCLUSIONS: These observations suggest that in children, as in adults, genetic, nutritional, and endocrine factors are determinants of the metabolism of homocysteine. The significance of tHcy values in childhood and young adulthood in terms of predicting cardiovascular risk in adulthood should be investigated.  (+info)

Effect of low-dose testosterone treatment on craniofacial growth in boys with delayed puberty. (8/1150)

Craniofacial growth was investigated in boys treated with low-dose testosterone for delayed puberty (> 14 years old; testicular volume < 4 ml; n = 7) and compared with controls (12-14 years; n = 37). Cephalometric radiographs, statural height and pubertal stage were recorded at the start of the study and after 1 year. Craniofacial growth was assessed by nine linear measurements. At the beginning of the study, statural height, mandibular ramus length, upper anterior face height, and total cranial base length were significantly shorter in the delayed puberty boys than in the controls. After 1 year, the growth rate of the statural height, total mandibular length, ramus length, and upper and total anterior face height was significantly higher in the treated boys than in the untreated height-matched controls (n = 7). The craniofacial measurements were similar in the treated boys as compared with the controls. These results show that statural height and craniofacial dimensions are low in boys with delayed puberty. Low doses of testosterone accelerate statural and craniofacial growth, particularly in the delayed components, thus leading towards a normalization of facial dimensions.  (+info)

TY - JOUR. T1 - Early pubertal maturation and risk of childhood asthma. T2 - A mendelian randomization and longitudinal study. AU - Chen, Yang Ching. AU - Fan, Hsien Yu. AU - Yang, Chen. AU - Lee, Yungling L.. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Background: Studies on early puberty and incident asthma have reported inconsistent results and are mainly performed in females. In this longitudinal study, we investigated the causal relationship between pubertal maturation and asthma through Mendelian randomization (MR) and explored the joint effect of overweightness and early pubertal maturation on asthma. Methods: We used data from the Taiwan Children Health Study with longitudinal follow-ups of 2991 children aged 11-17 years. Six puberty-related single-nucleotide polymorphisms (combined into a weighted allelic score) were used to yield genetic instrumental variables for early puberty. Early pubertal maturation was defined as reaching a certain pubertal stage earlier than the median age for that ...
Introduction: The identification of the onset of the pubertal growth spurt has major clinical implications when dealing with orthodontic treatment in growing subjects. Aim: Through multivariate methods, this study evaluated possible...
Boys had been recruited at age 8 or 9 years, and pubertal stage was assessed yearly based on testicular volume and genital maturity according to the Tanner Stages, a scale of physical development. Both the boys and their mothers provided blood samples for genetic and contaminant analyses at the study outset, and health, lifestyle, and diet data were collected through questionnaires.. Previous analyses had indicated that serum concentrations of dioxins and dioxin-like compounds were associated with later pubertal onset among these boys. The current study, conducted when the boys had reached age 12 or 13 years, investigated whether genetic variations modified this outcome.. The investigation included 392 boys and involved 337 SNPs identified in 46 genes and 2 intergenic regions (stretches of DNA between protein-coding genes) that may influence pubertal onset or the biological response to dioxins. The association of serum dioxins with later pubertal onset was confirmed, and two statistical methods ...
Everyone is different so everyone has a different experience of puberty. Some people go though puberty early, and some go though it late. This is almost always normal.. But with early and late puberty sometimes people can find it really tough. When you experience puberty at a different time to your peers it can make you feel and look different. Sometimes people use this as an opportunity to pay you out or bully you. People who experience late puberty can feel like they need to hide this from friends. ...
Puberty is the period of time during which a childs body changes into that of an adult. During this time, the body undergoes important hormonal shifts that facilitate the appropriate developmental changes.. Disorders of puberty may occur when there is a problem with the glands responsible for releasing the hormones responsible for puberty, such as the pituitary gland and hypothalamus, or when there is a problem with the reproductive organs themselves.. The most common puberty disorders include precocious (early) puberty and delayed (late) puberty. The evaluation of puberty disorders in adolescents may require blood testing, imaging studies, and sometimes genetic testing to identify the underlying cause and determine the proper treatment plan ...
This study was approved by the University of Minnesota Committee for the Use of Human Subjects in Research. Informed consent was obtained from the parents and informed assent from the children. The subjects were participants in a longitudinal study of the relation between insulin resistance and cardiovascular risk factors in children. The original cohort was randomly recruited after blood pressure screening of Minneapolis fifth- to eighth-grade public school children, as described previously (11). From this cohort, 323 insulin clamps were completed in pubertal children (Tanner stage II or greater) at mean age 13.1 ± 1.2 years. A second clamp was performed 2 years later in 300 of these participants at mean age 15.0 ± 1.2 years.. Before each insulin clamp, participants underwent a clinic examination and Tanner staging, as determined by pubic hair development in boys and breast and pubic hair development in girls. The greater of the two values in the girls was used to avoid underestimation of ...
The literature consistently shows an association between pubertal maturation and internalizing problems in girls. The association for boys is less
If you want to know what girls go through, have a look at puberty - things that change for girls.) Mostly, girls attain puberty at around age 12, and boys at around 13. Boys and puberty - what a topic. When your son is first in puberty, his breast tissue may swell a bit for a year or two as some of his hormones change into estrogen. Boys: Genital Changes. Puberty is a major change that happens in your body. 13 427 ... 0:10. Antiretroviral Therapy for HIV Infection in Infants and Children: Towards Universal Access: Recommendations for a Public Health Approach: 2010 Revision. Puberty Aaron Steve. The most common cause is called constitutional delayed puberty. Most boys who are constitutionally delayed are totally healthy and will go through puberty eventually. In this final stage, their testicles, scrotum, and penis all grow to their adult size, and pubic hair grows to normal adult volume and distribution. Puberty For Boys - Page 2 - Virtual Teen Forums ...
Clinical trial for Obesity | Polycystic Ovary Syndrome | Hyperandrogenemia , Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
The causes of early adrenal puberty and early gonadal puberty are different.. Early adrenal puberty: Sometimes, early adrenal puberty is normal. Other times, a problem with the adrenal glands can cause your daughter to have early adrenal puberty.. Early gonadal puberty: There are 2 types of early gonadal puberty, which have different causes. These are:. ...
Puberty is when your body starts to change as you move from being a kid to an adult. Some people go through puberty before the rest of their friends. Others grow later and have to wait and watch their classmates change. Either way, its important to remember that everyone goes through it.. When do boys start puberty? Boys usually start puberty when theyre around 10 or 12 years old, although some start a little sooner and others a little later. Boys usually start puberty later than girls.. What happens to a boy۪s body during puberty? There are many different changes that happen as boys go through puberty. For example,your voice will get deeper, youll probably begin to sweat more under your arms, and many boys will start to get pimples and grow hair under their arms. Also your testicles and penis will get bigger, and pubic hair will grow on your testicles and above your penis. These changes happen because our bodies release different growth hormones, and all of these changes are normal.. How ...
Sacramento, Calif. American girls are entering puberty at earlier ages, putting them at far greater risk for breast cancer later in life and for all sorts of social and emotional problems well before they reach adulthood.. Girls as young as 8 increasingly are starting to menstruate, develop breasts and grow pubic and underarm hair - biological milestones that only decades ago typically occurred at 13 or older. Black girls are especially prone to early puberty.. Theories abound as to what is driving the trend, but the exact causes are not known. A new report, commissioned by the San Francisco-based Breast Cancer Fund, has gathered heretofore disparate pieces of evidence to help explain the phenomenon - and spur efforts to help prevent it.. This is a review of what we know - its absolutely superb, said Dr. Marion Kavanaugh-Lynch, an oncologist and director of the California Breast Cancer Research Program in Oakland, which directs tobacco tax proceeds to research projects. Having something like ...
Around 15 percent of girls are going through puberty by age 7 -- and doctors cant explain why! According to a study of 1,239 girls, published in the journal Pediatrics, 15 percent of girls hit puberty by the age of 7, and the finding has doctors perplexed.
PHILADELPHIA: People whose genetic makeup triggers a later-than-average start to puberty have lower bone mineral density, especially in their lower spine. Because adolescence is a critical period for accruing bone, this effect may increase a persons risk of osteoporosis and bone fractures later in life..
RESULTS: The patients comprised 44 (26 males) who were prepubertal and 70 (36 males) pubertal or postpubertal, while 32 of the controls (19 males) were prepubertal and 41 (19 males) pubertal or postpubertal. The prepubertal children with hydrocephalus had lower IGF-I (p = 0.002) and IGFBP-3 concentrations (p < 0.001) than the controls, and the pubertal children had four times lower basal growth hormone concentrations (p < 0.001). There was a correlation between height SD score and IGF-I levels in the total patient population (r = 0.23; p = 0.01). Peripheral IGF-I concentrations peaked at pubertal stages 2-3 in the female patients and at stage 4 in the controls. The prepubertal patients on antiepileptic treatment, carbamazepine in most cases (73%), had higher IGF-I (p = 0.01) and IGFBP-3 concentrations (p = 0.03) than those who had never been treated with antiepileptic drugs, but still lower IGFBP-3 levels than the controls (p = 0.01 ...
On a recent winter press tour, Modern Family stars Ariel Winter, Sarah Hyland, and Nolan Gould described what it was like to go through puberty on television.
At puberty, sex hormones or gametes begin to be produced due to which the boys and girls become sexually mature.. The period during which adolescent boys and girls reach sexual maturity and become capable of reproduction is called puberty.. Puberty is a period of several years in which rapid physical growth occurs leading to sexual maturity.It tends to start earlier in girls than in boys.Girls attain puberty at a age of 10 to 13 yrs while boys reach puberty at a age of 12 to 14 yrs.. Changes which occur in boys during puberty are:. 1)Hair grow on the face in the form of moustache and beard, and on the chest.. 2)Voice deepens in boys.It becomes low pitched voice.. 3)Testes start to make sperm.. ...
Girls experience puberty as a sequence of events, and their pubertal changes usually begin before boys of the same age. The first pubertal change in girls usually is breast development.
Girls experience puberty as a sequence of events, and their pubertal changes usually begin before boys of the same age. The first pubertal change in girls usually is breast development.
Author(s): Herting, Megan M; Gautam, Prapti; Spielberg, Jeffrey M; Dahl, Ronald E; Sowell, Elizabeth R | Abstract: Sex hormones have been shown to contribute to the organization and function of the brain during puberty and adolescence. Moreover, it has been suggested that distinct hormone changes in girls versus boys may contribute to the emergence of sex differences in internalizing and externalizing behavior during adolescence. In the current longitudinal study, the influence of within-subject changes in puberty (physical and hormonal) on cortical thickness and surface area was examined across a 2-year span, while controlling for age. Greater increases in Tanner Stage predicted less superior frontal thinning and decreases in precuneus surface area in both sexes. Significant Tanner Stage and sex interactions were also seen, with less right superior temporal thinning in girls but not boys, as well as greater decreases in the right bank of the superior temporal sulcus surface area in boys compared to
New Orleans Scientists attempting to figure out why some girls go through puberty at unusually young ages have found a surprising culprit a gene that speeds up the bodys breakdown of the male sex hormone.. Many believe that the age of puberty the time when girls develop breasts and other sexual characteristics is decreasing. The most widely held explanation for this is growing childhood obesity, along with rich diets and lack of physical activity.. However, genes almost certainly play a role in the age of puberty, and many assumed that the most likely players in this scenario would be ones that control the bodys production and use of estrogen.. Research released Sunday at a meeting of the American Association for Cancer Research suggests a more complicated interplay of hormones, since the bodys supply of testosterone, the male hormone, seems to be a key influence on the timing of puberty.. Dr. Fred F. Kadlubar and colleagues from the Food and Drug Administrations National Center for ...
Pubertal height gain seems to be lower than previously reported on longitudinal growth in normal children, although no recent comparable reference values were available.9,31,32 Pubertal height loss was more pronounced in males. No substantial reduction of duration of growth was found. Loss of height potential during puberty seemed to be caused by a lower peak height velocity.8 In females, menarche occurred approximately six months later than in Dutch girls, resulting in an increase of duration of growth. The growth hormone IGF-I axis was not responsible for the loss in final height potential during puberty as normal to increased serum levels of IGF-I during puberty in treated CAH patients were found.33. In non-salt wasting patients, females were diagnosed earlier than NSW males with a less advantaged bone age and better height prognosis. In males, loss of final height was more pronounced because of late diagnosis. Prolongation of androgen excess induced true precocious puberty in 30% of the male ...
A new study shows that an increasing number of girls are hitting early puberty at age 7 or 8. Learn the health and social effects and get tips that may help delay puberty.
The indications for progressive resistive strength training for prepubescent children in sports training and rehabilitation have been a source of controversy. Eighteen prepubescent children, two at Tanner Stage II and the remainder at Tanner Stage I, were studied. Examination included anthropometric …
The foregoing analysis indicates that, in healthy prepubertal boys, two environmental or lifestyle factors, namely physical activity and protein intake, are positively associated with bone mineral mass at most measured skeletal sites. In multivariate regression analysis, physical activity with protein intake would account from 9% to 18% of the variance in BMC measured at the various skeletal sites. Calcium intake, which is also significantly associated with BMC in univariate analysis, does not seem to be an independent predictor when physical activity and protein intake are entered into the multiple regression equation. The apparent greater beneficial effect of physical activity than nutrition on bone mass acquisition has been suggested in two previous studies(16,17) on cohorts including both females and males and a wider age range (6-18 and 7-20 yr) than the foregoing report and consequently various stages of pubertal maturation. As in our study, the calcium intake did not remain an ...
At the transition from childhood to adolescence period, our bodies produce certain hormones which lead to bodily changes called Puberty. Puberty is natural way of transforming a child into an adult. Puberty is the stage where both girls and boys will go through many changes including physical, emotional, psychological and social. While both girls and boys go through puberty, girls in general reach puberty and sexual maturity at earlier ages than boys do. Some of us develop faster and some later. Puberty normally occurs from the ages 10-16 ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Last week, it was widely reported that American girls of this generation are starting puberty earlier than their counterparts in the early 90s. There have been a variety of articles about this, mostly framed around the increase of young white girls who are reaching puberty as early as age 7. However, the disparate rates for young Black and Latina girls have always reflected a serious public health issue.. Based on the aforementioned study conducted in the mid-2000s but recently published in the journal Pediatrics, more than 10% of white 7-year-old girls had reached a stage of breast development marking the start of puberty, compared to just 5 percent in a similar study conducted in the early 1990s. It is also noted in the article that nearly one-quarter (23%) of black girls (up from 15%) and 15% of Hispanic girls had entered puberty by age 7, but the researchers say that the trend is not statistically significant (in terms of methodology). While that offers an explanation why the press ...
The study, published in Scientific Reports, confirms previous findings that early puberty in women is a risk factor for heart disease and type 2 diabetes, and showed, for the first time, that early puberty in men also influences these same conditions.. In addition, new links were found between the timing of puberty and a wider range of health conditions, including irritable bowel syndrome, arthritis, glaucoma, psoriasis and depression in men and women, and also early menopause in women.. Researchers tested data from nearly half a million people in UK Biobank, a national study for health research funded primarily by the [Medical Research Council Epidemiology Unit at the University of Cambridge] and the Wellcome Trust. Participants were asked to recall puberty-timing by remembering the age of their first monthly period for women and age at voice-breaking for men.. Those in the earliest or latest 20 percent to go through puberty had higher risks for late-life disease when compared to those in the ...
BACKGROUND: The pattern of growth of the uterus was examined by ultrasound examinations of 358 girls who attended a paediatric endocrine outpatient department but were shown not to have any endocrine defect. METHOD: The uterus was measured in length and width at the cervix and at the fundus (cm). Endometrial thickness was measured (mm). Scans were divided by Tanner breast stage and the dimensions compared by one way analysis of variance (ANOVA, with the Student Newman Keuls post hoc test). RESULTS: There was an increase in uterine length, diameter of the fundus, and endometrial thickness at each breast stage from 1 to 5 (ANOVA, p , 0.05), and in the diameter of the cervix with each breast stage from 1 to 4 (ANOVA, p , 0.05). The ratio of the fundus to the cervix increased from 0.95 to 1.29 between breast stages 1 and 4. CONCLUSION: The onset of puberty is marked by an increase in the dimensions of the uterus and in endometrial thickness, but also by a change in the shape of the uterus from a ...
In humans, puberty is the period of physical development when sexual reproduction can first take place. It is characterized by maturity of the sexual organs and the development of secondary sexual characteristics (such as the deepening of a boys voice or the development of a girls breasts). The beginning of menstruation in females also begins in puberty. (Menstruation is the monthly cycle of the shedding of the lining of the uterus in women who are not pregnant.) The growth spurt experienced in puberty is characteristic of primates. Although other mammals may have increased reproductive organ growth, their overall size does not increase as dramatically. Puberty marks the physical transition from childhood to adulthood. It usually occurs between the ages of 10 and 16, with females entering the stage earlier than males. Both sexes experience considerable increases in body height and weight during this period and require a balanced, nutritious diet with sufficient calories for optimal growth. ...
Puberty is the sign of beginning of fertility and is a reproductive years. The puberty in girls happens at the age of 10 - 16 years. Coming to female, puberty is accompanied by a large increase in the production of hormones. The puberty in girls begins with a physical and emotional change in womanhood. As soon as the puberty begins, then your brain starts releasing hormones, which are called as a gonadotrophin releasing hormone. This is a releasing hormone, which helps in triggering out the pituitary gland to release luteinizing hormone and a follicle stimulating hormone. But, you can notice that boys hormones trigger in the production of testosterone and sperm in the testes. Whereas in girls, these hormones can stimulate the ovaries to produce oestrogen and progesterone. This is a large increase in oestrogen, progesterone, FSH and LH that causes the physical changes, which results in periods. Periods starts as and when two and a half years after the girls breasts start to develop. The onset ...
Going Through Puberty: A Boys Manual for Body, Mind, and Health Adolescence Childrens Nonfiction Ebook by Ruth Hickman, Md Hickman Ruth J., Ruth J. Hickman, Md Ruth J. Hickman,
Learning how to sing when going through puberty will prevent you from becoming frustrated and possibly even damaging your voice. Patience is key, but there are some exercises and things you can do to ease your vocals through this transformative process.
Hi Im a 13yo turning 14yo male. Is this a sign of me going through puberty. When I masterbait I produce some liquid and I have a couple of hairs growing down there.
The generally accepted indicator of early puberty in girls is the onset of a menstrual cycles before age twelve. However we are now seeing cases of breast and pubic hair development as early as age seven. So what constitutes early puberty is now under debate and researchers are seeking to understand whats driving this phenomenon? One surprise suspect is the absence of a father in the home. Learn more.
Puberty is the process of physical changes through which a childs body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a girl, the testes in a boy. In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs. Physical growth-height and weight-accelerates in the first half of puberty and is completed when an adult body has been developed. Until the maturation of their reproductive capabilities, the pre-pubertal physical differences between boys and girls are the external sex organs. On average, girls begin puberty around ages 10-11 and end puberty around 15-17; boys begin around ages 11-12 and end around 16-17. The major landmark of puberty for females is menarche, the onset of menstruation, which occurs on average between ages 12-13; for males, it is the first ...
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Despite the clear importance of adolescence in the emergence of a number of disease states and processes, there is surprisingly little known about how the endocrine and metabolic events accompanying puberty in humans impact normal developmental neurobiology. Epidemiologic studies have identified sexual dimorphisms in the prevalence of several neuropsychiatric disorders, including depression, schizophrenia, and substance abuse. Many of these sex differences emerge during or shortly after puberty and are maintained until the 5th-6th decade of life. For example, the two-fold greater risk of unipolar depression in women compared with men does not appear until adolescence, and prior to puberty girls are not at increased risk relative to boys. Puberty is a structured, transitional process that can be influenced by both nutritional factors and environmental stressors; nonetheless, the variability in the timing and duration of puberty is largely determined by oligogenic inheritance. Basic neuroscience ...
Long-term study results show which mechanisms of early-onset puberty in adolescent girls may predispose them to a greater risk of developing breast cancer.
Puberty concerns - MedHelps Puberty concerns Center for Information, Symptoms, Resources, Treatments and Tools for Puberty concerns. Find Puberty concerns information, treatments for Puberty concerns and Puberty concerns symptoms.
Why girls are far more likely to abuse drugs like speed, Ecstasy and cocaine than boys TEENAGE girls are being exposed to drugs earlier than boys and experimenting with a wider range of...
WASHINGTON - Boys in the US are hitting puberty as much as two years earlier than in previous decades, according to a new study out Saturday from the American Academy of Pediatrics.. The study suggests a well-documented trend seeing girls hit adolescence earlier than their historic counterparts has been mirrored among boys. However, the authors said the causes of change, or what it could mean for public health, remain unclear.. African-American boys were generally the earliest to start puberty, with boys as young as nine years old showing signs of maturation, according to data on more than 4,000 boys in 41 states, provided by their pediatricians offices.. Non-Hispanic whites were next, with the average age of puberty onset coming at just over 10 years old, while Hispanic boys hit puberty on average a few months later, at just under 10 and a half.. The ages were calculated based on when the pediatricians saw stage two genital and pubic hair growth.. ...
A teacher looks out on a sea of diversity when s/he looks at the students in any 4th or 5th grade classroom in the New Haven Public Schools where puberty education is part of the K-12 Social Development curriculum. The goals of puberty education are to help young people feel good about themselves as they grow and develop, to provide a healthy environment for beginning to learn about sexuality as a positive aspect of being human, and to begin to arm them with the knowledge, skills and attitudes theyll need to protect themselves against early pregnancy and diseases, including HIV/AIDS. The students are diverse in many ways, any one of which can have an affect both on their ability and willingness to learn about puberty and on the teachers strategies for teaching. My objectives in writing this curriculum unit are: to highlight the ways in which children are diverse as they progress through puberty; to address the specific educational needs of the 20% who may be precocious in becoming sexually ...
Brett Smith for redOrbit.com - Your Universe Online. Sometimes it seems like todays children are growing up faster than ever, and a new study published in the journal Pediatrics has found that American girls are indeed entering puberty earlier than ever before. The study also found a strong connection between female childhood obesity and the early onset of puberty.. The impact of earlier maturation in girls has important clinical implications involving psychosocial and biologic outcomes, said Dr. Frank Biro, author of the new study and a physician at Cincinnati Childrens Hospital Medical Center. The current study suggests clinicians may need to redefine the ages for both early and late maturation in girls.. Girls that physically mature faster than others run higher risks of having lower self-esteem, higher rates of depression, engaging in disruptive behavior, and lower academic performance. The early onset of puberty is also related to greater risks of obesity, cardiovascular problems and ...
The teenage years are also called adolescence. During this time, the teenager will see the greatest amount of growth in height and weight. Adolescence is a time for growth spurts and puberty changes. An adolescent may grow several inches in several months followed by a period of very slow growth, then have another growth spurt. Changes with puberty may happen gradually or several signs may become visible at the same time. There is a great amount of variation in the rate of changes that may happen. Some adolescents may experience these signs of maturity sooner or later than others. It is important to remember that these changes happen at different times for everyone. Being smaller or bigger than other girls is normal as each child experiences puberty at her own time. ...
The teenage years are also called adolescence. During this time, the teenager will see the greatest amount of growth in height and weight. Adolescence is a time for growth spurts and puberty changes. An adolescent may grow several inches in several months followed by a period of very slow growth, then have another growth spurt. Changes with puberty may occur gradually or several signs may become visible at the same time.. There is a great amount of variation in the rate of changes that may occur. Some adolescents may experience these signs of maturity sooner or later than others. It is important to remember that these changes happen at different times for everyone. Being smaller or bigger than other girls is normal as each child experiences puberty at her own time. ...
The teenage years are also called adolescence. During this time, the teenager will see the greatest amount of growth in height and weight. Adolescence is a time for growth spurts and puberty changes. An adolescent may grow several inches in several months followed by a period of very slow growth, then have another growth spurt. Changes with puberty may occur gradually or several signs may become visible at the same time.. There is a great amount of variation in the rate of changes that may occur. Some adolescents may experience these signs of maturity sooner or later than others. It is important to remember that these changes happen at different times for everyone. Being smaller or bigger than other girls is normal as each child experiences puberty at her own time. ...
TY - JOUR. T1 - Injury Risk and Injury Burden Are Related to Age Group and Peak Height Velocity Among Talented Male Youth Soccer Players. AU - Bult, Hans Jan. AU - Barendrecht, Maarten. AU - Tak, Igor Joeri Ramon. PY - 2018. Y1 - 2018. N2 - Background: The relationship between injury risk (IR) in age groups and periods around peak height velocity (PHV) remains unclear. PHV is defined as the moment of the largest increase in body height. Purpose: To investigate injury risk and injury burden as functions of growth velocity (periods around PHV) and chronological age groupings (under 12 years [U12] to U19) in talented youth male soccer players. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 170 players from the youth academy of a Dutch soccer club (highest professional league: Eredivisie) were observed for 1 to 3 seasons. Injuries, exposure, PHV age, and chronological age were registered. The injury incidence density (IID) and injury burden per 1000 hours of soccer ...
TY - JOUR. T1 - Relationship of neuropeptide FF receptors with pubertal maturation of gilts. AU - Thorson, Jennifer F.. AU - Heidorn, Neely L.. AU - Ryu, Vitaly. AU - Czaja, Krzysztof. AU - Nonneman, Danny J.. AU - Barb, C. Richard. AU - Hausman, Gary J.. AU - Rohrer, Gary A.. AU - Prezotto, Ligia D.. AU - McCosh, Richard B.. AU - Wright, Elane C.. AU - White, Brett R.. AU - Freking, Bradley A.. AU - Oliver, William T.. AU - Hileman, Stanley M.. AU - Lents, Clay A.. PY - 2017/3/1. Y1 - 2017/3/1. N2 - Mechanisms governing the timing of puberty in pigs are poorly understood. A genome-wide association study for age at first estrus in pigs identified candidate genes including neuropeptide FF receptor 2 (NPFFR2), which is a putative receptor for RFamide-related peptides (RFRP). RFRP has been shown to negatively regulate secretion of reproductive hormones from hypothalamic and pituitary tissue of pigs in culture. Here, the porcine NPFFR2 gene was further screened and four potentially functional ...
Epidemiological studies have observed a positive association between an earlier age at sexual development and prostate cancer, but markers of sexual maturation in boys are imprecise and observational estimates are likely to suffer from a degree of uncontrolled confounding. To obtain causal estimates, we examined the role of pubertal development in prostate cancer using genetic polymorphisms associated with Tanner stage in adolescent boys in a Mendelian randomization (MR) approach. We derived a weighted genetic risk score for pubertal development, combining 13 SNPs associated with male Tanner stage. A higher score indicated a later puberty onset. We examined the association of this score with prostate cancer risk, stage and grade in the UK-based ProtecT case-control study (n = 2,927), and used the PRACTICAL consortium (n = 43,737) as a replication sample. In ProtecT, the puberty genetic score was inversely associated with prostate cancer grade (odds ratio (OR) of high- vs. low-grade cancer, per tertile
Epidemiological studies have observed a positive association between an earlier age at sexual development and prostate cancer, but markers of sexual maturation in boys are imprecise and observational estimates are likely to suffer from a degree of uncontrolled confounding. To obtain causal estimates, we examined the role of pubertal development in prostate cancer using genetic polymorphisms associated with Tanner stage in adolescent boys in a Mendelian randomization (MR) approach.We derived a weighted genetic risk score for pubertal development, combining 13 SNPs associated with male Tanner stage. A higher score indicated a later puberty onset. We examined the association of this score with prostate cancer risk, stage and grade in the UK-based ProtecT case-control study (n = 2,927), and used the PRACTICAL consortium (n = 43,737) as a replication sample.In ProtecT, the puberty genetic score was inversely associated with prostate cancer grade (odds ratio (OR) of high- vs. low-grade cancer, per tertile of
TUESDAY, Dec. 26, 2017 (HealthDay News) -- A girl who gets her first menstrual period early in life -- possibly as young as 7 -- has a greater risk for developing depression and antisocial behaviors that last at least into her 20s, a new study suggests. Girls who go through puberty earlier than peers tend to be more psychologically vulnerable during adolescence, said study lead author Jane Mendle, a clinical psychologist and associate professor of human development at Cornell University. It hadnt been clear, though, whether that vulnerability extends past the teen years. Thats where the current study comes in. Mendle and her colleagues followed a group of almost 8,000 young women into their late 20s. Girls who went through earlier puberty are still showing higher rates of depressive symptoms and antisocial behavior than their peers well over a decade past adolescence, Mendle said. An early first period is a sign of early puberty. Mendle said theres no consensus on what constitutes an ...
Puberty is when your body starts to change as you move from being a kid to an adult. Some people go through puberty before the rest of their friends. Others grow later and have to wait and watch their classmates change. Either way, its important to remember that everyone goes through it.. When do girls start puberty? Girls usually start puberty between the ages of 9 and 11 years old, although some start a little sooner and others a little later. Girls often start puberty before boys.. What happens to a girls body during puberty? There are many different changes that happen when girls go through puberty. For example,your breasts will start to change in size and shape, your hips will start to widen, and pubic hair will begin to grow on your private parts and under your arms. Also your clitoris will grow a little too, and the inner lips of your vulva will become more prominent. (For more information on these body parts check out some anatomy).. During puberty, girls vulva become more sensitive. ...
Undernutrition during fetal and postnatal life is still a major problem in many low- and middle-income countries. Even in high-income countries malnutrition may exist in cases of intrauterine growth retardation, as well as in chronic conditions such as anorexia nervosa and inflammatory bowel disease. Children adopted from developing countries are often chronically malnourished. Nutritional rehabilitation, resulting in catch-up growth, is often complicated by influences originating in fetal life as well as during postnatal growth. This may result in hormonal and metabolic changes as well as alterations in pubertal development. The present review focuses on fetal, postnatal and fetal-postnatal undernutrition and subsequent catch-up growth as well as catch-up growth in relation to pubertal development. Catch-up growth in children can be associated with early puberty following fetal or combined fetal-postnatal undernutrition. However, early puberty does not seem to occur following catch-up growth after
Early puberty is associated with higher risk of adverse health and behavioral outcomes throughout adolescence and adulthood. US girls are experiencing earlier puberty with substantial racial/ethnic differences. We examined the association between breastfeeding and pubertal timing to identify modifiable risk factors of early puberty and potential sources of racial/ethnic differences in the timing of pubertal development. A prospective cohort study of 3331 racially/ethnically diverse girls born at Kaiser Permanente Northern California (KPNC) between 2004 and 06. All data were obtained from KPNC electronic clinical and administrative datasets. Mother-reported duration of breastfeeding was obtained from questionnaires administered at each well-baby check-up exam throughout the babys first year and categorized as Not breastfed, Breastfed | 6 months, and Breastfed ≥6 months. Pubertal development data used Tanner stages assessed by pediatricians during routine pediatric checkups starting at age 6.
Pubic hair development by age pics - Indices were calculated for Door on Welfare in. Passage at Caloundra the turning tide brought a degrees.
There was made a determination of the correlation relationships (CR) between indices of physical and sexual development (SD) of 1997 adolescents aged from 11 years 6 months to 17 years 5 months 29 days residing in the industrial center of the Southern Urals characterized by high levels of air pollution (API 7-13). Benzo(a)pyrene and formaldehyde contribute the greatest part to air pollution. The level of SD, time of appearance of secondary sexual characteristics was revealed to be interrelated with the pace of physical development of adolescents, regardless of the gender Children with an accelerated pace of physical development (macrosomatotype) are characterized by advancing sexual development and the earlier appearance of secondary sexual characteristics. Slow pace of physical development (microsomatotype) is characterized by SD retardation and the later appearance of secondary sexual characteristics. The degree of intensity of secondary sexual characteristics and such anthropometric indices ...
We found a significant incidence of GH deficiency in children treated with both cranial irradiation and chemotherapy for nonpituitary-related brain tumors. Fourteen of these 18 prepubertal or early pubertal children had confirmed GH deficiency. We did not detect GH deficiency in any individuals treated with only chemotherapy or cranial and/or spinal irradiation alone. Most of those children who received irradiation without chemotherapy and did not develop GH deficiency received radiation localized to the tumor area rather than to the whole brain, resulting in a lower radiation dose to the hypothalamic-pituitary area. However, the small numbers in the study did not permit analysis of the independent effects of chemotherapy or cranial irradiation. We found that linear growth appears to reflect GH status accurately in children with brain tumors. Those children confirmed subsequently as GH-deficient clearly grew more slowly from soon after brain tumor diagnosis. We did not test those children with a ...
The relationship between physical activity and clustering of metabolic risk factors was investigated in a population sample of Danish pre- or early pubertal children. Physical activity was significantly related to metabolic risk, after adjustment for potential confounding factors. Furthermore, we observed a significant interaction between physical activity and fitness, suggesting a stronger relationship between activity and metabolic risk, in children with low cardiorespiratory fitness.. None of the children in this study was diagnosed with metabolic pathology. The metabolic syndrome Z score, which we used to define metabolic risk clustering on a continuous scale, is statistically more sensitive and less error prone by comparison to dichotomous approaches (18). The Z score should correlate well with the true level of metabolic risk because its subcomponents are measured relatively precisely. In contrast to metabolic syndrome, the primary exposure, habitual physical activity, is highly variable ...
TY - JOUR. T1 - Alterations in the Pulsatile Properties of Circulating Growth Hormone Concentrations during Puberty in Boys. AU - Martha, Paul M.. AU - Rogol, Alan D.. AU - Veldhuis, Johannes D.. AU - Kerrigan, James R.. AU - Goodman, David W.. AU - Blizzard, Robert M.. PY - 1989/9. Y1 - 1989/9. N2 - To investigate the mechanisms subserving physiological alterations in circulating GH concentrations during puberty, we assessed the GH pulse characteristics of 60 24-h serum GH profiles obtained from healthy male volunteers of normal stature (aged 7-27 yr) whose physical development spanned the entire pubertal range. Subjects were divided into five study groups based on degree of sexual maturation. The mean 24-h concentration of GH was greater in late pubertal boys than in all other groups (P , 0.001). This elevation primarily reflected a greater size, rather than number, of GH pulses, whether assessed as mean GH pulse area (P = 0.004 vs. all other groups), mean GH pulse amplitude (P = 0.001), or ...
The possible differential regulation of pulsatile follicle stimulating hormone (FSH) and luteinizing hormone (LH) secretion in pre-pubertal children and in post-menopausal women was investigated. Children were studied for 4 h and post-menopausal women for 6 h; blood samples were taken every 10 min. Post-menopausal women were studied before and 21 days after administration of a single i.m. dose of gonadotrophin-releasing hormone (GnRH) analogue. Eight post-menopausal women and 18 children (nine boys and nine girls) were enrolled. The children were divided into two groups: A, at Tanner stages 0-1 (four boys and three girls); B, at Tanner stage 2-3 (five boys and six girls). Plasma LH and FSH concentrations were determined using an immunofluorimetric assay. Time series were analysed and the specific concordance (SC) index was computed to determine the degree of concordance between episodes of LH and FSH secretion. While children of group A had LH concentrations below the minimal detectable dose of ...
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The social brain undergoes developmental change during adolescence, and pubertal hormones are hypothesized to contribute to this development. We used fMRI to explore how pubertal indicators (salivary concentrations of testosterone, oestradiol and DHEA; pubertal stage; menarcheal status) relate to brain activity during a social emotion task. Forty-two females aged 11.1 to 13.7 years underwent fMRI scanning while reading scenarios pertaining either to social emotions, which require the representation of another persons mental states, or to basic emotions, which do not. Pubertal stage and menarcheal status were used to assign girls to early or late puberty groups. Across the entire sample, the contrast between social versus basic emotion resulted in activity within the social brain network, including dorsomedial prefrontal cortex (DMPFC), the posterior superior temporal sulcus, and the anterior temporal cortex (ATC) in both hemispheres. Increased hormone levels (independent of age) were associated with
Development of the breasts during the prenatal stage of life is independent of biological sex and sex hormones.[20] During embryonic development, the breast buds, in which networks of tubules are formed, are generated from the ectoderm.[21] These rudimentary tubules will eventually become the matured lactiferous (milk) ducts, which connect the lobules (milk containers) of the breast, grape-like clusters of alveoli, to the nipples.[22] Until puberty, the tubule networks of the breast buds remain rudimentary and quiescent,[1] and the male and female breast do not show any differences.[20] During puberty in females, estrogen, in conjunction with GH/IGF-1, through activation of ERα specifically (and notably not ERβ or GPER),[23][24] causes growth of and transformation of the tubules into the matured ductal system of the breasts.[20][21][25] Under the influence of estrogen, the ducts sprout and elongate, and terminal end buds (TEBs), bulbous structures at the tips of the ducts, penetrate into the ...
For a small subset of boys and girls who undergo early puberty, theres now a specific explanation. New genetic research, involving whole-exome sequencing, has identified four novel heterozygous mutations in a gene known as MKRN3. Interestingly, while precocious puberty is more common in girls, all 15 affected children in the study inherited the mutations from their fathers.. Precocious puberty-the development of secondary sexual characteristics before 8 years in girls and 9 years in boys-has been associated with short stature, long-term health risks and an increase in conduct and behavioral disorders during adolescence. Physiologically, there are two types: central and peripheral. Central, the more common form, occurs when the pituitary gland, which controls puberty development, is activated too early.. While a great deal of genetic studies have focused on the overall genetic contribution to pubertal timing, far less research has been conducted to find specific genetic causes of central ...
Joy. Puberty, the time when kids develop physically and emotionally into young adults, usually begins around 8 to 15 years of age. But for some kids it can happen much earlier. The medical term for this early development is precocious puberty.. Precocious puberty might be the result of a problem in the brain or a hormonal imbalance, but more often theres no specific underlying health issue. Some kids just have an early timer.. A doctor who specializes in early puberty can help distinguish between normal early development and a medical issue, and can help with treatment if it is needed.. Going through puberty early can be difficult on any child emotionally and socially, but can be even more difficult if that child is too young to understand whats happening. Give your daughter a simple, truthful explanation about whats happening, and keep her informed about what can be expected along the way.. Reviewed by: Steven Dowshen, ...
Findings of studies presented at International Congress of Neuroendocrinology June 19 22, , , , PITTSBURGH, June 21, 2006 Going through puberty at a young age might foretell problems to come, report r...
My 7-year-old daughter seems to be starting puberty already - should I be concerned? Your daughter should see a pediatrician. Precocious puberty is the term for the onset of puberty at an abnormally early age (in girls, puberty normally occurs between age 9 and 16). The incidence of precocious puberty has been rising in recent years. Among Caucasian girls today, one in seven exhibits signs of puberty before age 8. Among African-American girls, the number is one out of two. It is widely believed that obesity and hormonal disruption from environmental factors are responsible for such early maturation (for example, the hormones fed to dairy cows and meat animals to promote growth still reside in that food when we eat it later). There are other factors to consider as well. Our concern includes the fact that an earlier onset of menstruation is associated with a higher lifetime risk of breast cancer. - Gary Anderson, M.D., F.A.A.P. Providence Little Company of Mary Medical Institute, Torrance ...
1. What is adolescence?. Adolescence is the period between 10 -19 years. It is a unique period during which you transform from a child into an adult.. 2. What is puberty?. Physical, emotional and sexual growths are the hallmark of puberty. These changes are controlled by the sex hormones.. 3. When will I go through puberty?. Girls start puberty earlier (between 9 to 13 years) than boys (between 9.5 to 14 years). However, everyone goes through puberty at his /her own pace. There is no need to distress yourself by comparing yourself with others.. 4. What are pre-pubertal signs?. Pre-pubertal signs show that puberty could be expected to happen after 2 years. In a girl the area round the nipple starts to swell a little (breast buds) around 9-11 years; in a boy, the skin of the scrotum will start getting dark around 10-11 years.. 5. How does puberty begin? Puberty starts when impulses in your brain trigger the hormones of the pituitary gland (the main endocrine gland in your body and situated in the ...
Background Identifying standard pubertal growth patterns using longitudinal anthropometric steps is definitely important in growth assessment. included in this study. Height in boys and girls was similar at age 6.5 to 9.5 years. Girls subsequently grew faster and were taller than boys at age 10.5 to 11.5 years. Starting at age 12.5 years, male height caught up and exceeded female height. Height gain trajectories showed that annual height gain among girls increased slowly and peaked during age 9.5 to 11.5 years, while male height gains declined Rabbit polyclonal to ZNF75A slightly at first and peaked at age 11.5 to 12.5 years. Sex differences in height gains were significant during the period from age 7.5 to 14.5 years GSK1059615 (< 0.0001). Growth rate and height gain trajectories were similar between sexes. Conclusions Sex differences in growth trajectory were significant, and female height gain peaked approximately 2 years earlier than male height gain. (height gainor growth rate+ 3 sex+ 4 age ...
Thanks for your question. During puberty those who are sex-assigned at birth males will notice their testicles (or testes) becoming bigger, pubic hair development, and penile growth (length and width). They will also notice a growth spurt, voice changes, axillary hair (hair in your armpits), and facial hair. On average puberty will take 3 years to complete. However, puberty can last 2 to 5 years.. When you have a concern about puberty, a good first step is to check with your health care provider. They may:. ...
rating was Tanner stage 3 for breasts and stage 2 for pubic hair. An assessment of precocious puberty was made. Her investigation result showed an advanced bone age of 5 years; elevated serum gonadotrophins in the pubertal range; and essentially normal cranial CT. Abdomino-pelvic USS showed an enlarged uterus for age, and a dominant right follicle with internal echo measuring 17.1mm X 15.2mm. Parents were counseled on the need for treatment to arrest the progression of precocious puberty but yet to respond because of financial constraint after 2 years of diagnosis. Female precocious puberty is ten times more common than male precocious puberty. The aetiology is idiopathic in 90% of cases and It is amenable to treatment. Integration of the investigation and treatment of childhood endocrine disorders into the National Health Insurance scheme will be a great panacea to the challenge of prompt management in developing countries.. Keywords: Precocious, puberty, 24 months old, female, idiopathic, ...
neonatal factors. Menarche is also preceded by breast development (thelarche), which is exquisitely sensitive to the very low levels of estrogen that result from peripheral conversion of adrenal androgens and the low levels of estrogen secreted from the ovary early in pubertal maturation. Breast development precedes the appearance of pubic and axillary hair in ˜60% of girls. The interval between the onset of breast development and menarche is ˜2 years. There has been a gradual decline in the age of menarche over the past century, attributed in large part to improvement in nutrition, and there is a relationship between adiposity and earlier sexual maturation in girls. In the United States, menarche occurs at an average age of 12.5 years (Table 347-1). Much of the variation in the timing of puberty is due to genetic factors, with heritability estimates of 50-80%. Both adrenarche and breast development occur ˜1 year earlier in black compared with white girls, although the timing of menarche ...
Just in case US parents had managed to make it through the week without adding something new to their list of THINGS TO BE WORRIED ABOUT (Have you seen this article on drowning and children [1]?), I thought I would nominate one more new anxiety candidate this Friday the 13th: early puberty [2].Todays news includes a raft of reports on the phenomenon that has been noted before among American girls [3], may also be affecting American boys, and includes new reports of the syndrome affecting babies (!) in China [4]. USNWR reports: Ten percent of 7-year-old white girls are already developing breasts, as are 23 percent of black girls, and 15 percent of Hispanic girls, according to a new study from Cincinnati Childrens Hospital Medical Center [5], which appears in the September issue of Pediatrics. Those numbers are greater than they were 10 to 30 years ago, and appear to still be on the rise for white girls.Why is this happening? The suspect list is quite long and includes bovine growth hormone ...
For most parents, few developmental milestones are more dreaded than their daughters starting puberty. The idea of their sweet, innocent little girl turning into a moody, hormonal young woman is enough to keep most moms and dads up at night. The only saving grace for some of these parents is the belief that puberty is still years away.. But what if, even with a daughter still in kindergarten, the physical and emotional rollercoaster ride of puberty is lurking just around the corner? According to a recent study by the American Academy of Pediatrics, this is reality for more and more American families. The study followed girls of various ethnicities, locations and backgrounds, and found that by 7 years old, more than 10 percent of Caucasian girls and 23 percent of African-American girls showed signs of breast development, indicating that puberty has begun.. Plenty of children are not psychosocially capable of handling the emotional and physical changes of an early puberty. -Diane Stafford,MD ...
A new study shows that American girls are hitting puberty earlier than ever, with 15% of the 1,239 girls studied showing signs of breast development at age 7. Man, I didnt get the bra talk from my mom until I was at least 10!. One in 10 white girls, twice as many as in a 1997 study, showed breast growth by that age, as did 23% of black girls and 15% of Hispanic girls. Though the study, which was published in the journal Pediatrics, doesnt give a concrete reason why girls are developing earlier, Frank Biro, director of adolescent medicine at Cincinnati Childrens Hospital Medical Center, where the study was conducted, said it did that find heavier girls with a higher BMI were more likely than others to begin puberty early. Reaching puberty earlier can mean higher risk of breast and endometrial cancer later in life, possibly due to increased exposure to estrogen. This is to say nothing of the increased risk of self-esteem issues, eating disorders, depression, and all the fun stuff that ...
A few years ago, someone informed me that young girls are more bosomy and beginning puberty at younger ages, because of the hormones they are drinking in milk. These bovine growth hormones (BGH) are being given to dairy cows to increase milk production, the life of their herds and farmers profits.. This week I read that some Chinese babies between 4-15 months fed formula with BGH are actually growing breasts. I also read that more U.S. girls are beginning puberty at younger ages, like 7 or 8, than occurred in studies 20 years ago. This may be attributed to obesity or chemicals in the environment and could lead to greater likelihood of breast cancer.. My main point is how at risk we are to illness or harm just from eating what used to be regarded as healthy foods. Its not enough to avoid junk food and fast food. Now milk is a danger. To avoid high cholesterol foods, I avoid egg yolks, organ meats like liver, ice cream. I am told sugar, specifically fructose, is loved by cancer cells. So I ...
As I go through puberty its really really difficult. Its extremely hard when your body is experiencing changes. If I can share with any girl or boy who experiencing bumps on face or skin problem or you hate your teeth or hair or body. Its all natural for us to think we are Ugly. Its okay. Whats not okay if you allow your situation to control you or let someone bully you because you dont feel like. Listen up! Take charge Smile and beyou. You deserve to be love by friends that respect us and want make fun of our problems. Look in the mirror everyday before school and say I love me I can do this I have big dreams and I beautiful no matter what one person think. We all are unique and different in our own way. Smile and walk with confidence. Also remember never let no one break your spirit.. Written By: Gabrielle AKA GabbyNorthStar. ...
From birth to old age a persons body changes constantly. Growth and development in puberty consists of not only physical changes, but changes in emotions, personality, behavior, thinking, and speech as well. In other words, your boy or girl is a child before puberty and by the end of puberty he or she becomes an adolescent. During these years they are expected to mature or change from thinking, feeling, adjusting and acting like a child to ways of a grown up.. Puberty in females can start from ages of 9 and 14 and in males between the ages of 10 to 17 years. Physical appearance of both boys and girls changes during puberty and each develops stronger sexual characteristics. The change of puberty can take from one to six years. This is a general time frame which can vary and every child follows a unique, individual path. The period of adolescence can be a difficult time due to the physical and emotional changes. The hormonal changes that occur in adolescence can cause socio-emotional effects ...
Puberty that happens early is called precocious puberty. This means a childs physical signs of sexual maturity develop too soon. This includes breast growth, pubic hair, and voice changes. These are known as secondary sexual characteristics. Precocious puberty happens before age 8 in girls, and before age 9 in boys.
Puberty that happens early is called precocious puberty. This means a childs physical signs of sexual maturity develop too soon. This includes breast growth, pubic hair, and voice changes. These are known as secondary sexual characteristics. Precocious puberty happens before age 8 in girls, and before age 9 in boys.
London: Men who have considerable weight gain between their childhood and puberty are at an increased risk of having asthma as an adult, as are their future offspring, a new study has found.. The findings suggested that the period between the age of eight and puberty is particularly important for lung health later in life.. If one gains a lot of weight during this period, it doubles the risk of having asthma later in life, for both sexes, but for the boys the risk also doubles for his future offspring, said co-author Marianne Lonnebotn from the University of Bergen, Norway.. The study, presented at the ERS International Congress 2018 in Paris, also showed that the asthma risk was not related to weight gain before or after puberty.. There is a lot going on in the body between childhood and adult. All the organs are developing. Being overweight may lead to an overall inflammation in the body, which may interfere with the development of the organs in this period, said lead author Cecilie ...
USA Patient Meeting 2013. Notes taken. Part 2. Growth spurt.The growth spurt seen in late puberty in both males and females is controlled primarily by testosterone and oestrogen levels under the influence of growth hormone. Normally height will increase until the pre-determined height is reached and then the end plates of the long bones fuse &…
NIEHS Grants U01ES012770, U01ES012771, U01ES012800, U01ES012801, U01ES019435, U01ES019453, U01ES019454, U01ES019457, P01ES009584, P30ES006096, T32ES010957. Research that is part of the NIEHS Breast Cancer and the Environment Research Program found that breast development is occurring at an earlier age, and that earlier development was strongly associated with greater body mass index (BMI). Earlier than average maturation is a risk factor for obesity and hypertension, as well as breast, ovarian, and endometrial cancer.. From 2004 to 2011, the researchers followed girls in the San Francisco Bay Area, Greater Cincinnati, and New York City who were 6 to 8 years old when enrolled in the study. At regular intervals, trained and certified staff used Tanner staging to assess sexual maturity. They found that the age at onset of breast development (stage 2) varied by race/ethnicity, BMI at baseline, and geographical site. For African American, Hispanic, white non-Hispanic, and Asian participants, the ...
Study Purpose: This study has 8 specific aims: (1) To examine the developmental progression of intentions, in the early grades, and use of substances across the school years (grades 1 through 12) and one-year post-high school. (2) To examine the impact of key life transitions on changes in substance use, and the processes by which these transitions lead to changes in substance use, namely (a) the transition to middle school, (b) the transition to high school, and (c) pubertal maturation and the timing of pubertal maturation. (3) To examine the effect of demographic, personal, familial, peer, school, and neighborhood factors, on the development of use of alcohol, tobacco, marijuana, and inhalants, as well as on the development of other problem behaviors and health-risk behaviors related to substance use. (4) Examine the concurrent and across time associations of substance use with high risk sexual behavior and problem behaviors in mid adolescence to emerging adulthood to identify predictors of ...
Smoking cannabis may cause early puberty and stunted growth in boys.. Scientists studied hormones in the blood of 437 boys, including 217 who habitually smoked cannabis before reaching puberty.. They found that levels of puberty-related hormones such as testosterone were raised in the drug users, who also had reduced levels of growth hormones.. By the age of 20, non-cannabis smokers were on average four kilograms heavier and 11.6cm taller than smokers. ...
An article in New Capital Times discussed accusations by a handful of parents that infant formula caused the early onset of puberty in infants and young children. There is no conclusive link between early puberty and milk powder, but experts say its possible there is a connection. The parents blame the formula since their babies didnt eat anything else that could have caused the phenomenon. This incident is not related to the melamine incident ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Laurie and Debbie say:. Last July, Laurie met a woman who worked for Planned Parenthood and taught sex ed in Bay Area schools. She said that she now teaches in junior high school and high school but that she wanted to be teaching in elementary schools as well. She said the puberty beginning at 7 was not uncommon. Laurie was probably more surprised than maybe she should have been, and did some research about it. We included it as part of our conversation at the Kids and Body Image Panel at BlogHer. The fact that puberty is starting significantly earlier for girls and boys is not new news. The quotes below are from a study about 10 years ago. There are new guidelines for pediatricians that are guaranteed to shock: girls who start to develop breasts and pubic hair at age six or seven are not necessarily abnormal. (Kaplowitz, et al., 1999). ….Results found that in their seventh year, 27% of African-American girls and 7% of white girls had begun breast development and/or had pubic hair. Between ...
A new study performed by researchers at the Harvard School of Medicine, Boston, MA has revealed that early puberty in girls may be prompted by consumption of soda. The study was published in the journal Human Reproduction. The researchers followed almost 5,600 girls with ages from 9 to 14 between 1996 and 2001. The results of the monitoring showed that the girls who drank more than 1.5 servings … [Read more...] ...
Define puberty. puberty synonyms, puberty pronunciation, puberty translation, English dictionary definition of puberty. n. The stage of adolescence in which an individual becomes physiologically capable of sexual reproduction. pu′ber·tal , pu′ber·al adj. American Heritage®...
Looking for online definition of puberty in the Medical Dictionary? puberty explanation free. What is puberty? Meaning of puberty medical term. What does puberty mean?
Learn about Precocious Puberty and other health conditions at HealtheTreatment. What is Precocious Puberty? Compare Precocious Puberty symptoms Precocious Puberty treatments and . Share online in the health community.
Other roles of KNDy neurons include influences on prolactin production; puberty; stress' effects on reproduction; and the ...
Freud's book covered three main areas: sexual perversions; childhood sexuality; and puberty. Freud began his first essay, on " ... In his third essay, "The Transformations of Puberty" Freud formalised the distinction between the 'fore-pleasures' of infantile ...
"Puberty 2". Dead Oceans. June 17, 2018. Archived from the original on June 27, 2018. Retrieved June 27, 2018. "The Mitski ... "Reviews for Puberty 2 by Mitski". Metacritic. Archived from the original on December 2, 2016. Retrieved December 23, 2016. "The ... "Q&A: Mitski Goes Back To Her Roots On Puberty 2". June 8, 2016. Archived from the original on August 22, 2016. Retrieved August ... She announced her fourth studio album, Puberty 2, on March 1, 2016, and shared the lead single, "Your Best American Girl". She ...
... delayed puberty. Unlike Marfan syndrome, the cardiovascular system and the lens of the eye are unaffected.[citation needed] ...
A C8 Science Panel status report noted an association between exposure in girls and a later onset of puberty. Some other ... It was discovered after the children went through puberty that DES affected the development of the reproductive system and ... early puberty; brain and behavior problems; impaired immune functions; and various cancers. One example of the consequences of ... early puberty, obesity, and neurological problems. Early developmental stages appear to be the period of greatest sensitivity ...
... as a puberty blocker to prevent puberty in transgender girls and to treat early puberty in boys, and the treatment of long- ... Kreher, Nerissa C. (2007). "Familial Male-Limited Precocious Puberty". When Puberty is Precocious. pp. 383-401. doi:10.1007/978 ... Schoelwer, Melissa; Eugster, Erica A. (2015). "Treatment of Peripheral Precocious Puberty". Puberty from Bench to Clinic. ... these medications are less or not at all effective in peripheral precocious puberty, as this type of precocious puberty is ...
Brook CG (1999). "Mechanism of puberty". Horm. Res. 51 Suppl 3 (3): 52-4. doi:10.1159/000053162. PMID 10592444. Holmes SJ, ...
... choir is a choir primarily made up of choirboys who have yet to begin puberty or are in the early to middle stages of puberty ... "Disorders of Puberty". AAFP. Retrieved 2009-03-02. "Sex Abuse Scandal Haunts Harlem Boys Choir". ABC news. 2006-03-29. ... JSTOR article: Recording Bach's Early Cantatas - discusses the significance of the earlier onset of puberty.. ... The age of onset of puberty has declined to the early teens, so boys' choirs can no longer expect to retain a majority of their ...
Ellmann, Richard (1985-05-09). "Yeats's Second Puberty". The New York Review of Books. Retrieved 2017-08-23. McLaren, Angus ( ...
A 12-month subcutaneous implant (Supprelin LA) for central precocious puberty (CPP) was approved on May 3, 2007 by the U.S. ... In addition, histrelin has been proven to be highly effective in treating central precocious puberty in children. It is ... May 2007). "Efficacy and safety of histrelin subdermal implant in children with central precocious puberty: a multicenter trial ... Cohen, Deborah; Barnes, Hannah (20 September 2019). "Gender dysphoria in children: puberty blockers study draws further ...
On average, boys begin puberty at ages 11-12 and complete puberty at ages 16-17. In boys, puberty begins with the enlargement ... who usually begin puberty at about the age of 11 to 12 and complete it by the age of 16 to 17, on average). "Puberty: ... During puberty, a boy's erect penis becomes capable of ejaculating semen and impregnating a female. A boy's first ejaculation ... Puberty is the process by which children's bodies mature into adult bodies that are capable of reproduction. ...
Mapes, Jillian (June 22, 2016). "Mitski: Puberty 2". Pitchfork. Retrieved December 15, 2019. Fricke, David (June 16, 2016). " ...
"Spermaturia and puberty." Archives of Disease in Childhood 69.3 (1993): 384-387. Beatrice, Laura, et al. "Comparison of urine ...
Brook, CG (1999). "Mechanism of puberty". Hormone Research. 51 Suppl 3 (3): 52-4. doi:10.1159/000053162. PMID 10592444. ...
In a review of Puberty 2, Ciara Dolan of Consequence of Sound called the song one of the "Essential Tracks" from its parent ... It was also available as an instant gratification track for those who pre-ordered Puberty 2 on iTunes. "Your Best American Girl ... "Your Best American Girl" is a song by Japanese-American singer Mitski, from her fourth studio album, Puberty 2 (2016). The song ... Rettig, James (June 8, 2016). "Q&A: Mitski Goes Back To Her Roots On Puberty 2". Stereogum. Eldridge Industries. Retrieved May ...
He refuses to grow up, maintains his integrity and avoids acting like an adult in order to escape puberty. "The Book of ... Dickstein, Lore (13 November 1994). "Escape From Puberty". The New York Times. Retrieved 3 October 2018. v t e. ...
At puberty, many girls find the sudden sprouting of pubic hair disturbing, and sometimes as unclean, because in many cases ... Before the onset of puberty, the genital area of both boys and girls has very fine vellus hair (stage 1). At the onset of ... Although generally considered part of the process of puberty, pubarche is distinct and independent of the process of maturation ... ISBN 978-0-7216-7284-7. Rogol, Alan D (2002). "Androgens and puberty". Molecular and Cellular Endocrinology. 198 (1-2): 25-29. ...
Basahhh...', Petualangan Masa Pubertas" ['Basahhh ...', A puberty story]. KapanLagi.com (in Indonesian). 13 August 2008. ...
... and delayed puberty. Zinc deficiency can be caused by a diet high in phytate-containing whole grains, foods grown in zinc ...
"Roadrunner (Puberty Mix)" 19. "K.I.S.S. (Keep It Simple Stupid)" (produced by Diamond D, co-produced by Q-Tip) 04. "Pubic Enemy ...
... from a straightforward constitutional delay of puberty. However, if puberty has not started by either age 14 (girls) or 15 ( ... If puberty is not apparent by the age of 16 then the person should be referred for endocrinological review. Post natal ... If no puberty is apparent, especially no testicular development, then a review by a reproductive endocrinologist may be ... The diagnosis is often one of exclusion found during the workup of delayed puberty. In males, the use of age appropriate levels ...
Precocious puberty is a condition where females experience puberty before the age of seven or eight years. Precocious puberty ... Puberty is considered delayed if breast development does not start before age 13 or if a female has not had her first period ( ... Precocious puberty can be identified using a pelvic ultrasound to assess the size of ovaries and uterus relative to the ... Bauer, Andrew J.; Francis, Gary L.; Poth, Merrily (May 2001). "Review of Precocious Puberty: Part III-Premature Thelarche and ...
CS1 maint: discouraged parameter (link) Rodman, Sara (2000-09-23). "Whoaaa - `Arthur' reaches puberty". Boston Herald. https:// ...
Carr also tells the story of how puberty left him with "big teeth" and a camp voice. "Puberty had been unkind. Whereas it had ...
Puberty: Physiology and Abnormalities. Springer. 2016. ISBN 9783319321202. Recurrent Pregnancy Loss: Evidence-Based Evaluation ... Authors: Sajal Gupta, Avi Harlev, Ashok Agarwal, 2015, ISBN 978-3-319-18307-7 Puberty: Physiology and Abnormalities. Editors: ...
... and breastfeeding Puberty (except if being used to treat precocious puberty or delay puberty) Liver diseases and liver ... CPA has also been used as a puberty blocker and hence as an antiandrogen and antiestrogen to suppress puberty in transgender ... CPA has been used at dosages of 50 to 300 mg/m2 to treat precocious puberty. CPA is useful in the treatment of hot flashes, for ... CPA is used as an antiandrogen and antiestrogen to treat precocious puberty in boys and girls. However, it is not fully ...
Seizures cease near puberty. Seizures may require anticonvulsant treatment, but sometimes are infrequent enough to allow ...
"Puberty Stages of Development". Ask the Expert FAQs. OBGYN.net. Archived from the original on 2006-05-02. Retrieved 2006-11-21 ... In severe cases of VBH, hypertrophy of the clitoris occurs.[citation needed] At the onset of puberty, some females with who ... The breasts had begun to grow rapidly at puberty and had reached the point of causing physical impairment and respiratory ... Only 15% of cases of breast hypertrophy are unrelated to puberty or pregnancy. Other types and causes of breast hypertrophy ...
Estrogen is responsible for the mediation of puberty in females, and in girls with delayed puberty due to hypogonadism (low- ... 548-. ISBN 978-3-642-96158-8. Jennifer E. Dietrich (18 June 2014). Female Puberty: A Comprehensive Guide for Clinicians. ... Chris Hayward (31 July 2003). Gender Differences at Puberty. Cambridge University Press. pp. 22-. ISBN 978-0-521-00165-6. ...
Early onset puberty causes emotional issues at preschool age Archived April 16, 2013, at the Wayback Machine Boaz, N.T. (1999 ... Li W, Liu Q, Deng X, Chen Y, Liu S, Story M (October 2017). "Association between Obesity and Puberty Timing: A Systematic ... In very rare instances, menarche may occur at an unusually early age, preceding thelarche and other signs of puberty. This is ... Atay Z, Turan S, Guran T, Furman A, Bereket A (July 2011). "Puberty and influencing factors in schoolgirls living in Istanbul: ...
Puberty which starts earlier than usual is known as precocious puberty, and puberty which starts later than usual is known as ... On average, girls begin puberty at ages 10-11 and complete puberty at ages 15-17; boys generally begin puberty at ages 11-12 ... Several studies about puberty have examined the effects of an early or a late onset of puberty in males and females. In general ... True puberty is often termed "central puberty" because it begins as a process of the central nervous system. A simple ...
Excessive menstruation between puberty and 19 years of age is called puberty menorrhagia. Excessive menstruation is defined as ... In case of puberty menorrhagia due to immaturity of hypothalamic axis, hormonal therapy is beneficial. Treatment for blood loss ... The most common physiological reason for puberty menorrhagia is the immaturity of hypothalamic-pituitary-ovarian axis, leading ... The most common cause for puberty menorrhagia is dysfunctional uterine bleeding. The other reasons are idiopathic ...
puberty *Puberty is the process of physical changes by which a childs body becomes an adult body capable of reproduction. ... boys erections puberty A woody is an upredictable thing!. At twelve, Noah finds he cant control what his woody does. It pops ... Puberty is a painting created by Edvard Munch. Munch is an artist native to Norway and is widely known for his role in ... Boys Erections Puberty erections *(erection) erecting: the act of building or putting up ...
Delayed puberty is described as delayed puberty with exceptions when an organism has passed the usual age of onset of puberty ... Precocious puberty. References[edit]. *^ Villanueva C, Argente J (2014). "Pathology or normal variant: what constitutes a delay ... Chapter 9. Puberty & Fertility. *^ Male Hypogonadism. Friedrich Jockenhovel. Uni-Med Science. 2004. ISBN 3-89599-748-X. Chapter ... Delay of puberty may also occur due to malnutrition, many forms of systemic disease, or to defects of the reproductive system ( ...
Puberty can be delayed for several reasons. Luckily, doctors usually can help teens with delayed puberty to develop more ... This is called delayed puberty.. What Causes Delayed Puberty?. Puberty can be delayed for several reasons. Most often, its ... What Is Delayed Puberty?. Puberty is the time when your body grows from a childs to an adults. Youll know that you are going ... Dealing With Delayed Puberty. It can be really hard to watch your friends grow and develop when the same things not happening ...
Puberty is the time in life when a boy or girl becomes sexually mature. It causes physical changes, and affects boys and girls ... Understanding Puberty (For Parents) (Nemours Foundation) * What Are Normal Puberty, Precocious Puberty, and Delayed Puberty? ( ... What Are the Symptoms of Puberty, Precocious Puberty, and Delayed Puberty? (National Institute of Child Health and Human ... Delayed puberty in boys (Medical Encyclopedia) Also in Spanish * Delayed puberty in girls (Medical Encyclopedia) Also in ...
Puberty can be a confusing time, but learning about it doesnt have to be. Read all about it in this article for kids. ... OK, so its a funny word - but what is puberty, anyway?. Puberty (say: PYOO-ber-tee) is the name for the time when your body ... As you enter puberty, the puberty hormones stimulate the glands in your skin, including the sweat glands under your arms. When ... Usually, puberty starts between ages 8 and 13 in girls and ages 9 and 15 in boys. This wide range in ages may help explain why ...
Definition Precocious puberty [2] is sexual development before the age of eight in girls, and age 10 in boys. ... Precocious puberty. Definition. Precocious puberty is sexual development before the age of eight in girls, and age 10 in boys. ... There is no way to prevent precocious puberty.. KEY TERMS. Puberty -The point in development when the ability to reproduce ... "Accelerated versus slowly progressive forms of puberty in girls with precocious and early puberty." Journal of Pediatric ...
The change from girl to woman starts with early puberty and culminates in the first period. With these changes, come questions ... Puberty. When should puberty start?. Puberty in girls usually starts at any time between 8 and 13 years of age, periods usually ... Puberty (girls). The change from girl to woman starts with early puberty and culminates in the first period. With these changes ... What happens during puberty?. A girl grows and changes in ways that prepare her to be able to have a baby. These changes occur ...
In boys, delayed puberty is defined by the absence of testicular development by the age of 14. In girls, it is defined by the ... Delayed puberty is a condition that refers to the absence or late onset of sexual changes that usually occur at the age of ... Although the prevalence of delayed puberty is not known with precision, variation from the normal age of puberty occurs in ... In boys, delayed puberty is defined by the absence of testicular development by the age of 14. In girls, it is defined by the ...
High-Molecular Weight Phthalates Linked to Later Puberty Onset * Coal-Burning Stoves in Mongolia Linked to Seasonal Variance in ...
Central precocious puberty is a condition that causes early sexual development in girls and boys. Explore symptoms, inheritance ... The protein produced from the MKRN3 gene plays a role in directing the onset of puberty. Puberty begins when a gland in the ... Central precocious puberty is a condition that causes early sexual development in girls and boys. While puberty normally starts ... The cause of central precocious puberty is often unknown. The most common known genetic cause of central precocious puberty is ...
Treatments and Tools for Puberty concerns. Find Puberty concerns information, treatments for Puberty concerns and Puberty ... MedHelps Puberty concerns Center for Information, Symptoms, Resources, ... Posts on Puberty concerns. Could I have A DSD? - Teen Health Community ... Im 18 years old and have hit puberty for sure because Im 6 foot 3 and I have hair growing... ...
Remake of Puberty Blues (1981) See more » Soundtracks. Heroes Written by David Bowie (uncredited) and Brian Eno (uncredited) ... Puberty Blues is a picture of Australian suburban life in revolution as the wild kids get their rocks off, exploring the worlds ... Puberty Blues is an Australian classic which chronicles a special moment of our history. In the early 1970s, the middle baby ...
Precocious puberty: In healthy girls living in a temperate climate, the earliest sign of puberty (the beginning of breast and ... True precocious puberty is a condition in which normal pituitary-gonadal function is activated at an abnormally early age. ... Precocious puberty. In healthy girls living in a temperate climate, the earliest sign of puberty (the beginning of breast and ... True precocious puberty is a condition in which normal pituitary-gonadal function is activated at an abnormally early age. " ...
A new study shows a rapid trending downwards of the average age of girls beginning puberty, and the escalating rates of ... I bristle at the notion that the solution for this is preventing early puberty instead of fighting a culture that turns a blind ... It makes evolutionary sense that the body would start puberty once enough fat has accumulated that the body can support a ... And, as the researchers pointed out, the earlier you go through puberty the higher your chances of suffering from various ...
See what to expect as your child goes through puberty. WebMD shows you the changes youll see, including growth spurts, acne, ... Puberty usually begins for girls before boys. For most girls, puberty begins around age 11. For boys, puberty starts from 10 to ... Acne: An Early Sign of Puberty. Mild acne may be normal in early puberty. Pubertys high hormone levels can trigger acne ... Later Stages of Puberty for Girls. About a year after puberty begins, girls have a growth spurt. A girl will get taller and ...
What is Delayed Puberty in Boys?. Delayed puberty is when your son does not show the first signs of puberty by the time he is ... What is Normal Puberty?. Normal puberty is when childrens bodies start to grow and develop into young adult bodies. Boys ... Adrenal puberty. This is when the adrenal glands make hormones that cause the first signs of puberty including body odor, ... Gonadal puberty. This is when the pituitary gland (a small gland in the brain that controls other glands in the body) makes ...
Puberty can be a tough time for all teens, but especially for those with autism. A mother of two autistic sons explains the ... Puberty can be especially hard on autistic teens and their families. *"Hes angry and hes sad . . . and he doesnt understand ... Puberty is causing chaos in Alexanders once-predictable world. He cant talk and struggles to express himself. "Hes angry and ... And when he reached puberty, his behavior became much worse.. "Ever since I can remember, Connor would throw random fits," said ...
Scientists have identified mutations in a gene responsible for some cases of early puberty, an issue of growing concern to ... While parents may worry about the emotional toll caused by early puberty, doctors say theyre concerned because early puberty ... which normally acts as a brake to keep children from entering puberty. Mutations in that gene may allow puberty to begin too ... Doctors define early puberty as the development of secondary sex characteristics before age 8 in girls and before age 9 in boys ...
The age at which puberty starts in U.S. girls has continued to drop, a new study finds, the latest to suggest that greater ... More evidence links girls obesity with earlier puberty. The age at which puberty starts in U.S. girls has continued to drop, a ... More evidence links girls obesity with earlier puberty The age at which puberty starts in U.S. girls has continued to drop, a ... The start of puberty (determined by a specific stage of breast development) was at a median age of 9.7 years old in white, non- ...
... describes the clinical condition in which the pubertal events start late (usually , +2.5 SD later than the mean ... Normal puberty is a time of life and a process of development that results in full adult maturity of growth, sexual development ... Normal puberty is a time of life and a process of development that results in full adult maturity of growth, sexual development ... Delayed puberty describes the clinical condition in which the pubertal events start late (usually , +2.5 SD later than the mean ...
If I do something wrong in someones eyes I can blame puberty. ... All persons of age 13-18 are supposed to be in puberty. ... So hows puberty going? I love it! Why? ill tell you why :D I have time to do things like making webpages, doing sports etc ... hey its puberty! I felt you offended me. You also answerred next to the question. I asked HOW is puberty not WHAT is puberty. ... How is your puberty? Hmm let me ask him - I think its pretty good I see puberty as some kind of free ticket for doing whatever ...
Puberty is initiated by gonadotropin-releasing hormone release from the hypothalamus followed by a complex sequence of ... The aim of this chapter is to summarize recent developments in the field of puberty control, focusing on the genetic, ... Clinically, the onset of puberty is announced by the appearance of secondary sex characteristics, in particular the appearance ... epigenetic, environmental, neuroendocrine, and metabolic components of the complex and coordinated process of puberty. In ...
What Causes Early Puberty in Girls?. The causes of early adrenal puberty and early gonadal puberty are different. ... Early gonadal puberty: There are 2 types of early gonadal puberty, which have different causes. These are:. *Gonadotropin ... Gonadotropin independent puberty. This type of puberty is caused by the ovaries working on their own or exposure to medication ... Early adrenal puberty: Sometimes, early adrenal puberty is normal. Other times, a problem with the adrenal glands can cause ...
Plus Marnis the founder of Grow and Know, a non-profit that is focused on developing girls and boys puberty books in low- ... Plus Marnis the founder of Grow and Know, a non-profit that is focused on developing girls and boys puberty books in low- ... They can support organizations like Grow and Know that are aiming to develop and scale-up distribution of puberty books to 10- ... They can support organizations like Grow and Know that are aiming to develop and scale-up distribution of puberty books to 10- ...
... which is when an adolescent does not start puberty at the same age range as their peers. ... Pediatric Delayed Puberty. Pediatric delayed puberty occurs when an adolescent (12-17 years of age*) does not start puberty at ... What are the different types of Pediatric Delayed Puberty?. Delayed puberty in girls. Delayed puberty in girls is when a female ... Delayed puberty in boys. Delayed puberty in boys is when a male adolescents testicles and penis havent gotten larger, and his ...
A girl whose biological father does not live in her household has a higher chance of entering puberty earlier than her peers, ... But these findings get us away from assuming that there is a simple, clear path to the earlier onset of puberty.. Father ... The hunt for an explanation to this trend is significant since girls who enter puberty earlier than their peers are not only at ... The age at which girls are reaching puberty has been trending downward in recent decades, but much of the attention has focused ...
Have a talk with your children about sex, puberty and relationships and help them stay healthy. ... The open, non-judgmental conversations you have with your children about sex, puberty, bodies, and relationships will help them ...
... then lined up the data with when her daughter started puberty. For girls, puberty begins with the first signs of breast ... "Puberty is a time when you feel scared, you feel alone," she said. "You feel like your friends arent listening to you, your ... Early puberty is a becoming a reality for many American girls, and it puts them at higher risk for depression and diseases such ... "There has been a trend toward earlier onset of puberty observed over the last few decades, and the reasons havent been sorted ...
  • And all girls, regardless of race or ethnicity, with greater obesity started puberty earlier. (usatoday.com)
  • To diagnose precocious puberty, the doctor may order blood tests to look for high levels of sex hormones. (kidshealth.org)
  • Delay of puberty may also occur due to malnutrition , many forms of systemic disease , or to defects of the reproductive system ( hypogonadism ) or the body's responsiveness to sex hormones . (wikipedia.org)
  • While the early onset of puberty may seem fairly benign, in fact it can cause problems when hormones trigger changes in the growth pattern, essentially halting growth before the child has reached normal adult height. (encyclopedia.com)
  • Causes and symptoms Puberty begins when the brain secretes a hormone that triggers the pituitary gland to release gonadotropins, which in turn stimulate the ovaries or testes to produce sex hormones. (encyclopedia.com)
  • However, treatment with sex hormones according to the sex of the individual (testosterone or estrogen) can help to boost the hormone levels and induce puberty. (news-medical.net)
  • There's some suggestion that environmental estrogens could play a role, but that's unproven, while it's well-known that body fat does produce hormones that can kick start puberty. (slate.com)
  • When your son starts to go through puberty, his gonads (testes) and adrenal glands (glands that sit on top of the kidneys) release hormones. (massgeneral.org)
  • These hormones cause the first signs of puberty, which are an increase in the size of the testes and length of the penis, body odor, underarm hair, pubic hair and acne (pimples). (massgeneral.org)
  • This is when the adrenal glands make hormones that cause the first signs of puberty including body odor, underarm hair, pubic hair and acne (pimples). (massgeneral.org)
  • By taking a gonadotropin-releasing hormone (GnRH) agonist, secretion of the sex hormones can be stopped and the onset of puberty suppressed, so that the body does not develop secondary sex characteristics. (businessinsider.com)
  • This has been done safely for decades to suppress sex hormones in children who develop too early, a condition known as precocious puberty. (businessinsider.com)
  • These data suggest that gender differences in response to caffeine emerge after puberty," the authors conclude, "Future research will determine the extent to which these gender differences are mediated by physiological factors, such as steroid hormones, or psychosocial factors, such as more autonomy and control over beverage purchases. (medscape.com)
  • During puberty, the production of sex hormones causes other physical changes, including breast development in females and deepening of the voice in males. (thefreedictionary.com)
  • For example, if the reason for late puberty is lack of hormones, hormone medication can help. (familydoctor.org)
  • Obesity, hormones and pesticide residues in your food, and precocious puberty can be viewed as a linked triad. (mercola.com)
  • Overweight children have elevated levels of insulin, an increased ability to convert hormones into estrogen, and an increased ability to store environmental toxins, all of which may contribute to early puberty. (mercola.com)
  • It is, however, directly linked to diet, and the primary reason why diet may be a driving factor behind the early puberty phenomenon is the excessive use of hormones and other estrogen-mimicking chemicals in livestock and dairy production. (mercola.com)
  • Studies suggest that earlier puberty, as measured by the age at first menstruation, can slightly increase the risk of breast cancer, probably because it results in longer lifetime exposure to the hormones estrogen and progesterone, which can feed some tumors. (care2.com)
  • While this is thought to interfere with sex hormones and puberty timing, few studies have explored this connection in human children. (reuters.com)
  • The other type is peripheral precocious puberty which results from production of sex hormones and can be caused by ovarian tumors or adrenal disorders. (redorbit.com)
  • From surging hormones and acne to body hair and body odor, puberty can be a rocky transition for any kid. (kqed.org)
  • Normally, the hypothalamus initiates puberty by stimulating the pituitary to release gonadotropins (FSH and LH), the hormones which control growth and function of the sex organs. (rarediseases.org)
  • Hormones, emotions and behavior tend to go hand in hand, which can lead to distress both in the child and her parents when puberty comes years ahead of schedule. (mercola.com)
  • Yes, it is true that the incidence of precocious puberty is increasing lately because of hormones in food, hormone-mimicking pollutants in the water and increased social exposure like sex in the mass media. (medindia.net)
  • Interestingly, there was no mention of the likely possibility of early puberty being linked to our food, specifically the hormones in our meat and dairy products, and whatever chemicals are in our overly processed foods. (feministing.com)
  • Puberty is the natural process of hormones signaling the growth of estrogen and female sexual characteristics in girls or testosterone and male sexual characteristics in boys. (bradley.edu)
  • Another important component of puberty is adrenarche, which is the release of hormones from the adrenal gland. (healio.com)
  • The main steroid hormones, testosterone, estradiol, and progesterone as well as prolactin play important physiological functions in puberty. (wikipedia.org)
  • Puberty is started by hormones , which are chemicals that tell parts of the body to do things. (wikipedia.org)
  • The gland makes hormones that cause males' and females' bodies to start puberty. (wikipedia.org)
  • Puberty is started and carried on by different hormones. (wikipedia.org)
  • If girl brains can order hormones to induce early puberty after seeing lots of nearby polygyny, how else might our bodies be contingent what our brains see about our social world? (overcomingbias.com)
  • Further testing demonstrated that the hormones responsible for triggering her physical changes were coming from her pituitary gland, the initiator of puberty, which signals certain hormones to instigate the process. (scpr.org)
  • Add one more reason to the long list of reasons to support Michelle Obama's initiative to prevent childhood obesity: it will help reverse the trend of girls starting puberty at younger and younger ages. (slate.com)
  • A new study shows a rapid trending downwards of the average age of girls beginning puberty, and the escalating rates of childhood obesity are being eyeballed as the likely culprit. (slate.com)
  • Early puberty is linked with obesity in girls. (webmd.com)
  • While parents may worry about the emotional toll caused by early puberty, doctors say they're concerned because early puberty increases a girl's later risk of breast cancer, endometrial cancer, heart disease, diabetes and obesity. (usatoday.com)
  • The age at which puberty starts in U.S. girls has continued to drop, a new study finds, the latest to suggest that greater obesity may be the primary factor. (usatoday.com)
  • While overweight and obesity alter the timing of girls' puberty, those factors don't explain all of the variance in pubertal timing. (medicalnewstoday.com)
  • Scientists know childhood obesity is associated with earlier puberty, but it doesn't tell the whole story, Kubo said. (mercurynews.com)
  • Health disparities are just getting wider and wider - minority populations have worse outcomes, earlier puberty and more childhood obesity," said Kubo. (mercurynews.com)
  • The study also found a strong connection between female childhood obesity and the early onset of puberty. (redorbit.com)
  • The early onset of puberty is also related to greater risks of obesity, cardiovascular problems and several types of cancer. (redorbit.com)
  • Experts aren't sure what's behind the increase in earlier puberty, but it's likely due to a combination of factors, including the childhood obesity epidemic and substances in the environment. (mercola.com)
  • As for what's causing the increasing in early puberty, chemicals in the environment, obesity, and above-average weight gain during infancy are all being considered as possible factors. (mercola.com)
  • But obesity is not a cause of early puberty in and of itself. (mercola.com)
  • The study showed total body obesity and excess belly fat in boys aged four-seven years were associated with greater odds of starting puberty before age nine. (ndtv.com)
  • With the increase in childhood obesity worldwide, there has been an advance in the age at which puberty begins in girls. (ndtv.com)
  • Among boys aged five or six, those with obesity had nearly 2.7 times the odds of starting puberty early. (ndtv.com)
  • Girls are starting puberty at younger ages - a full year earlier than previously reported in some cases - and the main factor associated with early breast development is obesity, according to a new long-term study released Monday. (sfgate.com)
  • Health experts say obesity is the biggest factor in the early onset of puberty, but the next step is to understand the factors that lead to obesity. (sfgate.com)
  • Cases included illustrate different causes of abnormal puberty as well as management strategies, including congenital anomalies, endocrine disorders, issues of constitutional delay, obesity, eating disorders, ovarian cancer and the effect of pharmacology, among others. (springer.com)
  • He said then that while it is too early to pinpoint any one cause, the rise in the rate of childhood obesity is a factor, and researchers have noted that heavier girls are more likely to start puberty earlier. (cincinnatichildrens.org)
  • Obesity, a well-established puberty accelerant, is high on the list of suspects. (overcomingbias.com)
  • Several recent studies suggest that the timing of the onset of puberty in girls has become earlier over the past 30 years, and there is strong evidence that the increasing rates of obesity in children over the same time period is a major factor. (aappublications.org)
  • The evidence published to date suggests that obesity may be causally related to earlier puberty in girls rather than that earlier puberty causes an increase in body fat. (aappublications.org)
  • The two main suspects are the rising incidence of childhood obesity (overweight girls tend to enter puberty earlier) and exposure to endocrine disruptors , chemicals that are known to disrupt the body's endocrine, or hormone, system. (minnpost.com)
  • They don't prove that obesity in pregnancy causes early puberty, only that the two conditions are associated. (babycenter.com)
  • The protein produced from the MKRN3 gene plays a role in directing the onset of puberty. (medlineplus.gov)
  • To help boys realize they are not alone in their concerns about masturbation, body hair, growth spurts (or lack thereof), female puberty, voice changes, perspiration, shaving, and sexuality, this classic guide is written in a down-to-earth, nonjudgmental style and filled with answers to the many questions boys have as their bodies begin the transformation into adulthood. (google.com)
  • Puberty is the period of life that leads to adulthood through dramatic physiologic and psychological changes. (nih.gov)
  • noun adolescence , teenage , teens , young adulthood , pubescence , awkward age , juvenescence Lucy had reached the age of puberty. (thefreedictionary.com)
  • Early puberty in boys, could lead to higher incidence of testicular cancer in adulthood. (ndtv.com)
  • Puberty, when a child's body matures into adulthood, has important implications not just for a lifetime of running but also for overall health. (runnersworld.com)
  • Puberty is a stage of biological transition from a child to adulthood. (medindia.net)
  • Puberty - The Transition From Child to Adult Puberty is the phase when physical changes take place in the body signifying the transition from childhood to adulthood. (medindia.net)
  • The fifth stage of puberty is considered fully mature adulthood. (modernmom.com)
  • Derived from the Latin puberatum (age of maturity), the word puberty describes the physical changes to sexual maturation, not the psychosocial and cultural maturation denoted by the term adolescent development in Western culture, wherein adolescence is the period of mental transition from childhood to adulthood, which overlaps much of the body's period of puberty. (wikipedia.org)
  • Some people don't realize they are transgender until they reach puberty, or later in adulthood. (washingtonpost.com)
  • Previous research shows that early puberty increases the risk of diseases in adulthood, for example, testicular cancer in men and breast cancer in women. (eurekalert.org)
  • Furthermore, early puberty - particularly an early menarche (first menstrual period) - is associated with an increased risk of type 2 diabetes in adulthood and with breast cancer . (minnpost.com)
  • It has also found there's no marked difference between boys' and girls' aggression levels when at the same stage of puberty. (nzherald.co.nz)
  • At the fully grown or adult stage of puberty, the testicles are generally about 1 ¾ inches long and between 16 and 27 milliliters in volume. (infobarrel.com)
  • It can be quite interesting to see a group of 11-year-old boys and girls, all in a different stage of puberty. (steamboatpilot.com)
  • The first stage of puberty is actually a starting point. (modernmom.com)
  • There is no sexual development in boys or girls in the first stage of puberty. (modernmom.com)
  • In the second stage of puberty, boys will develop a body odor and experience an enlargement of testicles. (modernmom.com)
  • The third stage of puberty is marked for boys by an enlargement of the penis, the growth of pubic hair and ejaculation, or wet dreams. (modernmom.com)
  • For boys, the penis and testes continue to enlarge in the fourth stage of puberty. (modernmom.com)
  • Girls experience the onset of menstruation in the fourth stage of puberty ,as well as the development of a distinction between the nipple and the areola. (modernmom.com)
  • For both boys and girls, the fifth stage of puberty is marked by pubic hair extending to the inner thighs. (modernmom.com)
  • And yet, talking about the issues of puberty remains an important job for parents because not all of a child's information comes from reliable sources. (kidshealth.org)
  • Puberty is the process of physical changes by which a child's body becomes an adult body capable of reproduction. (google.com)
  • Talk to your child's doctor about possible causes for the change in puberty pattern. (familydoctor.org)
  • Biro was careful to point out that BMI is just one of a host of factors that could be causing these girls to start puberty early and said parents shouldn't focus on their child's weight in order to delay puberty. (redorbit.com)
  • Before discussing puberty and sexuality with your child, it is important to understand the outside influences and sources of information your child is exposed to that may be detrimental to your child's understanding of healthy sexuality. (childrens.com)
  • Precocious puberty is when a child's body begins changing into that of an adult (puberty) too soon. (drugs.com)
  • Make an appointment with your child's doctor for an evaluation if your child has any of the signs or symptoms of precocious puberty. (drugs.com)
  • Estrogen or testosterone in your child's body causes this type of precocious puberty. (drugs.com)
  • Puberty marks the start of a child's sexual development and early onset could result in a higher risk of sexual abuse. (redorbit.com)
  • While some parents are resorting to drug treatment to keep puberty at bay in their prematurely developing daughters, a more proactive approach would be to limit exposure to endocrine-disrupting chemicals, starting as early before birth as possible, and to address your child's diet - specifically restricting all forms of sugar as much as possible. (mercola.com)
  • A child's need for calories rises during times of rapid growth, gradually increasing as she moves through middle childhood into puberty. (healthychildren.org)
  • Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. (wikipedia.org)
  • Because puberty is the time in a child's life when he or she becomes able to make children, this is seen as very important. (wikipedia.org)
  • Keeping your weight in check during pregnancy could reduce your child's chances of going through early puberty if she's a girl, according to a new study . (babycenter.com)
  • To find answers, I went to Marni Sommer, a faculty member of the Mailman School of Public Health, Columbia University , where she conducts research on adolescents' transitions through puberty in low-income countries, exploring gender, sexuality, reproductive and sexual health, and specifically how the onset of menstruation may be interrupting girls' education. (forbes.com)
  • Plus Marni's the founder of Grow and Know , a non-profit that is focused on developing girls' and boys' puberty books in low-income countries around the world in order to assure that young people all over the globe have enough information and guidance about the confusing changes happening to their bodies during puberty, and for girls specifically, guidance on how to comfortably and successfully manage their menstruation in school. (forbes.com)
  • Next, the researchers plan to release a series of studies that look at different stages of puberty, including the start of menstruation. (sfgate.com)
  • The definition of puberty in girls includes breast development, growth of pubic hair and onset of menstruation. (mercola.com)
  • Precocious puberty may be diagnosed in girls under 8 years old who experience menstruation, breast development, the growth of pubic or underarm hair, acne and/or a rapid growth in height. (bradley.edu)
  • The major landmark of puberty for females is menarche, the onset of menstruation, which occurs on average between ages 12 and 13. (wikipedia.org)
  • By the 1980s, the onset of puberty, if not actual menstruation, had gone into free fall-a change so sudden and pronounced that something more than normal evolution must have been at work. (overcomingbias.com)
  • Excessive menstruation between puberty and 19 years of age is called puberty menorrhagia. (wikipedia.org)
  • Some very young girls (usually from 6 months to 3 years old) may show breast development that later disappears or may last but without other physical changes of puberty. (kidshealth.org)
  • One of the main physical changes of puberty is the growth and development of the sex organs - used to have sex and make babies. (avert.org)
  • The production of estrogen and testosterone causes the physical changes of puberty. (drugs.com)
  • Girls attain reproductive maturity about four years after the first physical changes of puberty appear. (wikipedia.org)
  • The vast majority of children experiencing precocious puberty become lost in the crowd of their peers when their age peers enter puberty. (encyclopedia.com)
  • Because the earlier you enter puberty, the longer you're exposed to elevated levels of the female hormone estrogen, which is a risk factor for certain cancers such as breast cancer. (mercola.com)
  • Obese boys and girls are likely to enter puberty at an early age, which can result in stunted growth or depression, finds a new study. (ndtv.com)
  • Leptin-deficient mice and humans fail to enter puberty unless leptin is administered, and rodent studies indicate that very low levels of leptin stimulate gonadotropin secretion both at the hypothalamic and the pituitary level. (aappublications.org)
  • However, there is such a thing as precocious puberty (early onset) and delayed puberty. (familydoctor.org)
  • Early puberty, also known as precocious puberty, is defined as developing breasts and starting periods before the age of eight. (mercurynews.com)
  • Puberty which starts earlier than usual is known as precocious puberty, and puberty which starts later than usual is known as delayed puberty. (wikipedia.org)
  • Having frequent and honest discussions with your child about puberty before it happens, and sexuality, is an important way to help protect your child. (childrens.com)
  • It's best to talk to your child about puberty when he's still young. (news24.com)
  • The first sign of puberty is usually breast development. (medlineplus.gov)
  • In healthy girls living in a temperate climate, the earliest sign of puberty (the beginning of breast and pubic-hair growth) has traditionally been considered to occur at a mean age of 10.6 years (standard deviation of 1.2 years). (britannica.com)
  • Breast growth is usually the first sign of puberty girls will notice. (webmd.com)
  • The first sign of puberty in boys is subtle -- an increase in testicle size. (webmd.com)
  • The first sign of puberty in most boys is an increase in the size of the testicles and penis. (familydoctor.org)
  • This may be the first sign of puberty in boys. (jamaica-gleaner.com)
  • Some boys will start to grow pubic hair as a first sign of puberty, but for most boys, the genitals grow first. (infobarrel.com)
  • Central precocious puberty is a condition that causes early sexual development in girls and boys. (medlineplus.gov)
  • While puberty normally starts between ages 8 and 13 in girls and between ages 9 and 14 in boys, girls with central precocious puberty begin exhibiting signs before age 8, and boys with this disorder begin before age 9. (medlineplus.gov)
  • Central precocious puberty is estimated to affect 1 in 5,000 to 10,000 girls. (medlineplus.gov)
  • The cause of central precocious puberty is often unknown. (medlineplus.gov)
  • The most common known genetic cause of central precocious puberty is mutations in the MKRN3 gene. (medlineplus.gov)
  • Changes in other genes are rare causes of the condition, and researchers suspect that changes in genes that have not yet been identified may also be involved in central precocious puberty. (medlineplus.gov)
  • The MKRN3 gene mutations involved in central precocious puberty are thought to lead to production of a nonfunctional MKRN3 protein. (medlineplus.gov)
  • Either sons or daughters can have central precocious puberty, although researchers suspect that girls are more severely affected than boys, because the onset of puberty is even earlier than normal in girls than in boys. (medlineplus.gov)
  • When passed from parent to child, the condition is known as familial central precocious puberty. (medlineplus.gov)
  • These cases are called sporadic central precocious puberty. (medlineplus.gov)
  • Central precocious puberty results from premature activation of the hypothalamic-pituitary-gonadal axis. (uniprot.org)
  • Why this process begins early in some children depends on whether they have central precocious puberty or peripheral precocious puberty. (drugs.com)
  • In central precocious puberty, the puberty process starts too soon. (drugs.com)
  • the first is central precocious puberty (CPP) which results from premature activation of the HPG axis and in the majority of cases the cause is unknown. (redorbit.com)
  • What Are Normal Puberty, Precocious Puberty, and Delayed Puberty? (medlineplus.gov)
  • What is Normal Puberty? (massgeneral.org)
  • Normal puberty is when children's bodies start to grow and develop into young adult bodies. (massgeneral.org)
  • Normal puberty is a time of life and a process of development that results in full adult maturity of growth, sexual development, and psychosocial achievement. (nih.gov)
  • In most cases, early puberty is just a variation of normal puberty. (familydoctor.org)
  • Normal puberty commences from approximately 10 years onwards and breast development is usually the first sign of this. (redorbit.com)
  • This treatment is normally stopped when it is time for normal puberty to begin. (redorbit.com)
  • What Are the Signs & Symptoms of Precocious Puberty? (kidshealth.org)
  • But most need no treatment and will show the other expected signs of puberty at the usual age. (kidshealth.org)
  • Delayed puberty is described as delayed puberty with exceptions when an organism has passed the usual age of onset of puberty with no physical or hormonal signs that it is beginning. (wikipedia.org)
  • Signs of puberty include development of pubic and underarm hair, a rapid increase in height (commonly referred to as a "growth spurt"), acne, and underarm odor. (medlineplus.gov)
  • Delayed puberty is when your son does not show the first signs of puberty by the time he is 14 years old. (massgeneral.org)
  • Over time, boys will develop later signs of puberty, such as increased muscle mass, stronger bones, a deeper voice and a growth spurt. (massgeneral.org)
  • Early puberty is when your son starts showing the first signs of puberty before he is 9 years old. (massgeneral.org)
  • I have not seen any other signs of puberty. (medhelp.org)
  • They considered puberty signs that emerge before the start of the first menstrual cycle (menarche). (medicalnewstoday.com)
  • For girls, puberty begins with the first signs of breast development and the appearance of pubic hair. (mercurynews.com)
  • The signs of puberty are a teachable moment," says one doctor. (cnn.com)
  • The signs of puberty are a teachable moment,' adds Horn, herself a mom of two, ages 7 and 9. (cnn.com)
  • For a growing number of girls, the first signs of puberty are showing up earlier - sometimes as early as second grade. (greatschools.org)
  • But for the majority of girls who start to show signs of developing breasts in the second or third grade, precocious puberty is not what is happening. (greatschools.org)
  • In a report published by the American Association of Pediatrics, Kaplowitz and his fellow authors advise pediatricians faced with 7-year-olds showing signs of puberty, "Although a small number of such children have a disorder that requires thorough testing and treatment, the great majority of patients have benign, normal variants of puberty. (greatschools.org)
  • If your daughter shows signs of breast development earlier than her peers, it may be only slightly reassuring to know that she is experiencing a normal variant of puberty. (greatschools.org)
  • Among Caucasian girls today, one in seven exhibits signs of puberty before age 8. (dailynews.com)
  • Precocious puberty signs and symptoms include development of the following before age 8 in girls and before age 9 in boys. (drugs.com)
  • They tested mothers' urine during pregnancy and interviewed them about potential chemical exposures, then tested kids' urine for chemical exposure at 9 years old and examined children for signs of puberty development every nine months between ages 9 and 13 years. (reuters.com)
  • Sometimes, though, a much younger girl starts to show the signs of puberty. (nationwidechildrens.org)
  • These early signs of puberty can be hard for your child. (nationwidechildrens.org)
  • In addition to the early physical signs of puberty, although the child may initially present with tall stature as the bones mature faster, growth may cease early and compromise final adult height. (redorbit.com)
  • They were then reviewed periodically for signs of puberty from age 9 to 13, including breast development, pubic hair and periods in girls, and testicular development and pubic hair in boys. (news-medical.net)
  • There are many terms used to describe pre-pubertal children who have isolated signs of puberty. (rarediseases.org)
  • But two years before or after those ranges is also normal, which means girls can start showing signs of puberty as early as 8 years old, and as late as 14 years old. (steamboatpilot.com)
  • Parents must take their children to a healthcare provider if the child shows signs of precocious puberty or if a child with early development of sexual and physical characteristics appears to have social problems in school. (medindia.net)
  • Kids always seem to be growing up too fast, but Dr. Dina Kulik explains how to know when those early signs of puberty are actually abnormal. (todaysparent.com)
  • Board-certified endocrinologist Dr. Marcus Allen recommends that children have an MRI if they show signs of precocious puberty to rule out the possibility of a tumor in the brain. (thedoctorstv.com)
  • Most of the time there's nothing seriously wrong, but if your daughter is 7 or younger and is showing any signs of puberty, it's a good idea to let her doctor know in case she needs testing or treatment. (babycenter.com)
  • These findings demonstrate that such factors may play important roles in the onset of puberty in girls. (medicalnewstoday.com)
  • This study focused on breast development because budding breasts, more than pubic hair growth or other changes, are considered the true onset of puberty in girls. (sfgate.com)
  • The trend toward earlier onset of puberty in girls is now generally accepted and supported by extensive research. (aap.org)
  • The research found a linear relationship between exposure of phthalates, parabens and phenols and the onset of puberty in girls, although there was no similar observation in boys. (telegraph.co.uk)
  • The less common peripheral precocious puberty occurs without the involvement of the hormone in your brain (Gn-RH) that normally triggers the start of puberty. (drugs.com)
  • Puberty usually begins with the testicles and penis getting bigger. (medlineplus.gov)
  • The penis, measured in the stretched flaccid state, increases from an average length of 6.2 cm in pre-puberty to 12.4±2.7 cm in white adults and to 14.6 cm in black and 10.6 cm in Asian men (2). (nih.gov)
  • Delayed puberty in boys is when a male adolescent's testicles and penis haven't gotten larger, and his voice hasn't deepened and hair hasn't grown in a variety of places by age 16. (childrens.com)
  • As a boy goes through puberty his penis grows thicker and longer, and his testicles move lower down his scrotum (ball sack). (avert.org)
  • The size of the penis also increases during puberty. (infobarrel.com)
  • As puberty continues, the scrotum and penis continue to grow. (infobarrel.com)
  • At puberty, a boy's body begins making sperm and he starts to be able to ejaculate , which is semen coming out from his penis when he is sexually excited. (wikipedia.org)
  • Some theorize that perhaps the lack of a biological father may indicate an unstable family environment, resulting in earlier female puberty. (medicalnewstoday.com)
  • Comprised exclusively of clinical cases covering abnormal female puberty and its clinical management, this concise, practical casebook will provide clinicians in reproductive endocrinology, gynecology and pediatrics with the best real-world strategies to properly diagnose and treat the various forms of the condition they may encounter. (springer.com)
  • Pragmatic and reader-friendly, Abnormal Female Puberty: A Clinical Casebook will be an excellent resource for reproductive endocrinologists, gynecologists and pediatricians alike. (springer.com)
  • Princeton Health Community Wellness addresses the physical, intellectual and emotional changes during female puberty. (princetonol.com)
  • Early puberty has been associated with a higher probability of developing breast cancer and reproductive cancers later in life. (medicalnewstoday.com)
  • Puberty is characterized by the maturation of the hypothalamic pituitary gonadal (HPG) axis, which plays a critical part in the development and regulation of the reproductive system. (redorbit.com)
  • Altered puberty timing is also of concern for the development of reproductive tract cancers later in life. (aappublications.org)
  • Finally, altered puberty timing is considered an adverse effect in reproductive toxicity risk assessment for chemicals. (aappublications.org)
  • Whether it arrives when a girl is 9 or 15 years old, puberty spurs the development of breasts, the reproductive system, and a new stature. (runnersworld.com)
  • One particular area they plan to investigate is the potential link between early puberty and reproductive cancers . (psychcentral.com)
  • Puberty is made up of a clear sequence of stages , affecting the skeletal, muscular, reproductive, and nearly all other bodily sys-tems. (healthychildren.org)
  • Puberty is the process through which reproductive maturation occurs, and it is initiated by the hypothalamic-pituitary-gonadal (HPG) axis ( Figure 1 ). (healio.com)
  • While focusing on the hypothalamus, the bottom part of the brain that controls reproductive development, they found that a puberty-activating gene called Kiss1 was expressed differently in each rat type. (eurekalert.org)
  • Polygyny of both kinds creates a shortage of women in reproductive age, and thus, early puberty will be advantageous. (overcomingbias.com)
  • Early or precocious puberty is when a child reaches a physical or hormonal milestone -- breast, testes, or pubic hair growth -- before age 6 to 8 in girls or 9 in boys. (webmd.com)
  • Clinically, the onset of puberty is announced by the appearance of secondary sex characteristics, in particular the appearance of breast in females, testicular enlargement in males, and pubic/axillary hair in both sexes. (nih.gov)
  • Some girls can have "partial" precocious puberty and may have growth of pubic or underarm hair but no other sexual development. (nationwidechildrens.org)
  • In girls, early puberty or precocious puberty is defined as the development of secondary sexual characteristics, such as the development of breasts or pubic hair before the age of 8 years. (redorbit.com)
  • The stages of puberty are denoted by the advance of pubic hair for both boys and girls. (modernmom.com)
  • In girls, puberty starts with the development of breast buds, which is followed soon after by the development of pubic hair. (healio.com)
  • On average, girls start puberty between the ages of 8 and 13, but some will start to develop breasts, pubic hair, or body odor before age 8. (babycenter.com)
  • In the 21st century, the average age at which children, especially girls, reach puberty is lower compared to the 19th century, when it was 15 for girls and 16 for boys. (wikipedia.org)
  • A University of Queensland study has found that girls who experience puberty early are "significantly" more aggressive than their later developing peers by age 14. (nzherald.co.nz)
  • While males and females grow at about the same rates during childhood, females experience puberty and the adolescent growth spurt 2 years earlier than males. (prezi.com)
  • Becoming overweight at a young age can trigger a molecular chain reaction that leads some girls to experience puberty early, according to new research published in Nature Communications . (eurekalert.org)
  • Although the mechanism is unclear, researchers speculate that without the MKRN3 protein to inhibit GnRH release, the hypothalamus releases bursts of the hormone, which stimulates the onset of puberty earlier than normal. (medlineplus.gov)
  • And, as the researchers pointed out, the earlier you go through puberty the higher your chances of suffering from various cancers later in life. (slate.com)
  • In the new study, published in Wednesday's New England Journal of Medicine , researchers focused only on cases in which early puberty runs in the family. (usatoday.com)
  • Because researchers focused on so-called familial cases, the new study doesn't explain all examples of early puberty, or why the phenomenon is increasing, says study co-author Ursula Kaiser, chief of endocrinology at Brigham and Women's Hospital in Boston. (usatoday.com)
  • Researchers find earlier onset of puberty in non-Hispanic white girls in the USA. (usatoday.com)
  • A girl whose biological father does not live in her household has a higher chance of entering puberty earlier than her peers, say researchers from the University of California, Berkeley, in an article published in the Journal of Adolescent Health . (medicalnewstoday.com)
  • Caffeine affects heart rate and blood pressure differently after puberty in girls compared with boys, and the response of postpubertal girls varies across the menstrual cycle, according to a study by researchers at the University of Buffalo, New York, published online June 16 in Pediatrics . (medscape.com)
  • A 2012 study by researchers from the University of North Carolina's School of Public Health also found that boys were hitting puberty earlier as well - an average of six to 24 months ahead of what is considered healthy by medical professionals. (redorbit.com)
  • Girls exposed to chemicals commonly found in shampoo, toothpaste and soap may hit puberty earlier, even if their only exposure is through the products their moms used while were pregnant, according to a new longitudinal study led by researchers at UC Berkeley . (mercurynews.com)
  • And one limitation of the study is that researchers lacked data to know if girls going through puberty might be more likely to use these personal care products, and be directly exposed that way, the study authors note. (reuters.com)
  • According to the researchers, the timing and tempo of puberty vary dramatically across kids. (psychcentral.com)
  • In the future, the researchers plan to examine the effects of tempo of puberty on later women's health problems-particularly the relationship between early puberty and later women's health problems. (psychcentral.com)
  • It is also noted in the article that nearly one-quarter (23%) of black girls (up from 15%) and 15% of Hispanic girls had entered puberty by age 7, but the researchers say that the trend is not statistically significant (in terms of methodology). (feministing.com)
  • In the current study, the researchers examined blood pressure and heart rate before and after administration of placebo and two different doses of caffeine (1 and 2 mg/kg) to see what role puberty played in the differences. (medpagetoday.com)
  • The researchers confirmed that males had exaggerated responses to caffeine, but only in the participants who had already undergone puberty. (medpagetoday.com)
  • Researchers followed 338 children whose mothers enrolled in a health study in the last 1990s, measuring concentrations of phthalates, parabens and phenols during pregnancy and following up into puberty. (telegraph.co.uk)
  • Researchers from the University of North Carolina found that boys are now reaching puberty as early as 9 years old, when 30 years ago the average was 11 to 12 years of age. (thedoctorstv.com)
  • Because it is difficult to test the cause of environmental risk factors in humans, the researchers sought to identify in animals how pyrethroids alter the timing of puberty. (eurekalert.org)
  • Girls with precocious puberty, for example, may be confused or embarrassed about getting their periods or having enlarged breasts well before any of their peers. (kidshealth.org)
  • Pediatric delayed puberty occurs when an adolescent (12-17 years of age*) does not start puberty at the same age range as their peers. (childrens.com)
  • Reuters Health) - - Girls who are exposed before birth to chemicals commonly found in toothpaste, makeup, soap and other personal care products may hit puberty earlier than their peers who aren't exposed to these chemicals in the womb, a U.S. study suggests. (reuters.com)
  • Girls who start puberty earlier than their peers may experience difficulties and treatment may be required. (redorbit.com)
  • A 2018 study conducted by Mendle and her team found that girls who entered puberty significantly earlier than their peers were at higher risk for mental health concerns. (kqed.org)
  • However, during childhood, children with precocious puberty are often taller than their peers. (rarediseases.org)
  • Girls who experience a "precocious puberty" (as it's called in the medical world) are also more likely to start having sex at a younger age than their peers. (minnpost.com)
  • Starting puberty early can have a significant impact both psychologically and socially on both the child and her family. (redorbit.com)
  • Knowing how nutrition and specific molecules play a role in starting puberty early could one day help physicians prevent the condition in humans," said one of the study's corresponding authors, Alejandro Lomniczi, Ph.D., a research assistant professor at OHSU's Oregon National Primate Research Center. (eurekalert.org)
  • Here is the stages of puberty I have noticed so far: Age 13: I started to grow some pube. (medhelp.org)
  • My research and that of others subsequently has clearly showed that testosterone fails to rise adequately in late puberty (Tanner stages 4 and 5) and this can only be detected accurately by evaluating testosterone concentrations in the early morning. (bmj.com)
  • Puberty in girls - what are the stages and changes to the body? (avert.org)
  • The study is considered the largest and longest research project to follow girls throughout the stages of puberty. (sfgate.com)
  • It sounds like your daughter is in the early stages of puberty. (todaysparent.com)
  • When your son goes through puberty, his testosterone levels are increasing, meaning he might become stronger or more aggressive. (news24.com)
  • Between four to eight times more common in girls than boys, precocious puberty occurs in one out of every 5,000 - 10,000 U.S. children. (encyclopedia.com)
  • A period is the vaginal bleeding that women usually experience at regular intervals of about a month from puberty to menopause (the end of periods that, on average, occurs in your early 50s). (netdoctor.co.uk)
  • Although the prevalence of delayed puberty is not known with precision, variation from the normal age of puberty occurs in approximately 1 in 30 children. (news-medical.net)
  • Because genetic change occurs slowly over time, he said that lifestyle or environmental factors likely interact with genes to affect the age of puberty. (usatoday.com)
  • The mature stage (stage 5) occurs at the end of puberty or with a first pregnancy and is characterized by the projection of the papilla only, due to a recession of the areola to the contour of the breast (Fig. 1A). (nih.gov)
  • Ejaculation (release of sperm) during sleep occurs frequently during puberty. (jamaica-gleaner.com)
  • Precocious puberty" is the term for the onset of puberty at an abnormally early age (in girls, puberty normally occurs between age 9 and 16). (dailynews.com)
  • About 25 per-cent of human growth in height occurs during puberty. (healthychildren.org)
  • Puberty may be delayed for several years and still occur normally, in which case it is considered constitutional delay of growth and puberty, a variation of healthy physical development. (wikipedia.org)
  • Variation of normal (constitutional delay of growth and puberty). (wikipedia.org)
  • Children who are healthy but have a slower rate of physical development than average have constitutional delay of growth and puberty. (wikipedia.org)
  • Children with a combination of a family tendency toward short stature and constitutional delay of growth and puberty are the most likely to seek evaluation. (wikipedia.org)
  • It is often difficult to establish if it is a true constitutional delay of growth and puberty or if there is an underlying pathology, because biochemical tests are not always discriminatory. (wikipedia.org)
  • In addition, the main diagnostic and therapeutic aspects of variations of normal pubertal development such as premature pubarche and thelarche and constitutional delay of growth and puberty are also summarized. (nih.gov)
  • They include the occurrence of secondary characteristics beginning with breast development, the adolescent growth spurt, the onset of menarche - which does not correspond to the end of puberty - and the acquisition of fertility , as well as profound psychological modifications. (wikipedia.org)
  • In this study, 10% of white girls, 23% of black girls, and 15% of Hispanic girls age 7 had enough breast tissue to have started puberty. (slate.com)
  • The start of puberty (determined by a specific stage of breast development) was at a median age of 9.7 years old in white, non-Hispanic girls, 4 months earlier than in a landmark 1997 study that first documented early puberty in U.S. girls. (usatoday.com)
  • Early puberty is a becoming a reality for many American girls, and it puts them at higher risk for depression and diseases such as breast cancer. (mercurynews.com)
  • The study published in Pediatrics at the beginning of this month compared results from two previous studies that used breast development to gauge the beginning of puberty. (mercola.com)
  • The beginning of breast development in the early elementary years is sometimes referred to as "precocious puberty. (greatschools.org)
  • Of the girls studied, 10.4 percent of white 7-year-olds had breast development consistent with the onset of puberty, compared to 5 percent in a 1997 study, earlier studies had identified early puberty mainly in black girls. (care2.com)
  • This is troubling news because scientists have linked the early onset of puberty with greater risk of mental illness, breast and ovarian cancer in girls and testicular cancer in boys. (mercurynews.com)
  • Early onset of puberty is important because it is linked with a slightly higher risk of breast and ovarian cancer/testicular cancer in women and in men, respectively. (news-medical.net)
  • The median age for breast development is now around 9, with rare cases of extreme precocious puberty occurring in girls as young as 4. (mercola.com)
  • Precocious puberty is also associated with an increased lifetime risk of estrogen-sensitive breast cancer. (mercola.com)
  • For example, one 2013 study 3 found that early puberty was associated with a 30 percent higher risk for breast cancer compared to entering puberty at a later age. (mercola.com)
  • Based on the aforementioned study conducted in the mid-2000's but recently published in the journal "Pediatrics," more than 10% of white 7-year-old girls had reached a stage of breast development marking the start of puberty, compared to just 5 percent in a similar study conducted in the early 1990s. (feministing.com)
  • Early-onset puberty can lead girls to experience health problems later, including increased incidence of ovarian, uterine and breast cancers, as well as being at a higher risk for cardiovascular and metabolic diseases. (eurekalert.org)
  • Early puberty is of concern because it increases their risk of mental health problems and risk-taking behaviour as teenagers and increases their risk of breast and ovarian cancer. (telegraph.co.uk)
  • When talking to kids about puberty, it's important to be reassuring. (kidshealth.org)
  • Parents should start having conversations with kids about puberty before it begins. (steamboatpilot.com)
  • Speaking to your kids about puberty can be a daunting task at the best of times - even more so when a mom has to speak to her son. (news24.com)
  • There's usually no identifiable cause for this type of precocious puberty. (drugs.com)
  • Treatment will depend on the type of precocious puberty and the underlying cause, if known. (redorbit.com)
  • The cause of precocious puberty often can't be found. (drugs.com)
  • Often, the exact cause of precocious puberty is not known. (rarediseases.org)
  • The cause of precocious puberty is unknown, but it creates a host of emotional and physical problems for those affected. (thedoctorstv.com)
  • The incidence of precocious puberty has been rising in recent years. (dailynews.com)
  • Being familiar with the common causes and initial testing of abnormal puberty will allow the primary care provider to monitor appropriately and initiate further investigation if warranted. (healio.com)
  • There has been considerable concern about why girls are entering puberty earlier and hormone disrupting chemicals like the ones in personal care products that we studied have been suggested as one possible reason," said lead study author Kim Harley, associate director of the Center for Environmental Research and Children's Health at the University of California, Berkeley. (reuters.com)
  • Overall, African-American boys were more likely to start puberty earlier than white or Hispanic boys. (aap.org)
  • When should puberty start? (netdoctor.co.uk)
  • Puberty in girls usually starts at any time between 8 and 13 years of age, periods usually start about two years after the start of puberty. (netdoctor.co.uk)
  • At the start of puberty, the brain releases a hormone known as gonadotrophin-releasing hormone (GnRH). (netdoctor.co.uk)
  • It makes evolutionary sense that the body would start puberty once enough fat has accumulated that the body can support a pregnancy, and of course we know that severe anorexics often stop menstruating once they drop below a certain amount of body fat. (slate.com)
  • If you're not overweight, this usually happens right before you teenage years, but as kids get fatter younger, we're seeing puberty start to happen at much younger ages, at least in girls. (slate.com)
  • Toward the end of puberty, your son's voice may start cracking. (webmd.com)
  • Boys usually start to go through puberty between the ages of 9-14 years. (massgeneral.org)
  • Patterns run in families - if one or both parents had puberty start late, it can also begin later in their children. (childrens.com)
  • Testosterone should not be given, as loosely described by CH Blevins (p33), at the start of puberty, but in a much more considered manner. (bmj.com)
  • Puberty usually starts between 9 and 16 - exactly when varies from person to person, but girls often start younger than boys. (avert.org)
  • During puberty you may start thinking about sex. (avert.org)
  • Your nipples and breasts will start to fill out during puberty. (avert.org)
  • The start of puberty is caused by the hypothalamus (the part of the brain that controls the pituitary gland). (nationwidechildrens.org)
  • Some girls start puberty too early for no known reason. (nationwidechildrens.org)
  • A problem in the ovaries or thyroid gland could also start puberty early. (nationwidechildrens.org)
  • During puberty, boys start making sperm in the testicles. (infobarrel.com)
  • Girls who start puberty very early are more likely to have psychological problems and be at risk of sexual abuse and early pregnancy, suggests a new review published today (27 April) in The Obstetrician & Gynaecologist (TOG). (redorbit.com)
  • Girls who start puberty early can be affected both physically and psychologically, says the review. (redorbit.com)
  • However, about 15% of females start puberty much sooner - by the age of 7. (kqed.org)
  • Because information about early development tends to focus on girls, parents are often perplexed when their sons start puberty early, says Fran Walfish, a child and adolescent psychotherapist in Beverly Hills, Calif. (kqed.org)
  • Periods typically start a year or three after puberty begins. (runnersworld.com)
  • Girls have been experiencing puberty earlier in life for the last 150 years or so, with 12.5 years being the average age girls start puberty today. (eurekalert.org)
  • Today, on average, girls start puberty at age 10 or 11, and boys at age 11 or 12. (wikipedia.org)
  • However, people all over the world start puberty at different ages. (wikipedia.org)
  • This is the general picture, but people round the world may start puberty at different ages. (wikipedia.org)
  • Some studies have found that mothers and daughters tend to start puberty at about the same age. (wikipedia.org)
  • Boys and girls who have a good diet - who eat healthy food - tend to start puberty earlier. (wikipedia.org)
  • [16] Today, people start puberty younger than in the 1840s. (wikipedia.org)
  • Young people who exercise a lot, such as athletes and gymnasts , may start puberty later. (wikipedia.org)
  • All of this would have reflected an ordinary start of puberty had it not been for one significant difference: Isabel wasn't a preteen with dreams of dancing with her current crush. (scpr.org)
  • Precocious puberty is sexual development before the age of eight in girls, and age 10 in boys. (encyclopedia.com)
  • Precocious puberty often begins before age eight in girls, triggering the development of breasts and hair under the arms and in the genital region. (encyclopedia.com)
  • Demographics Not every child reaches puberty at the same time, but in most cases it is safe to predict that sexual development will begin at about age 11 in girls and 12 or 13 in boys. (encyclopedia.com)
  • Puberty - The point in development when the ability to reproduce begins. (encyclopedia.com)
  • In boys, delayed puberty is defined by the absence of testicular development by the age of 14. (news-medical.net)
  • Doctors define early puberty as the development of secondary sex characteristics before age 8 in girls and before age 9 in boys. (usatoday.com)
  • But puberty has to do with the development of adult sexual organs. (sitepoint.com)
  • Research has already shown that a mother's health during pregnancy dramatically influences her baby's development in those first nine months and long into the future, and a smaller previous study by Kubo suggested there was a connection between a mother's weight during pregnancy and when her daughter starts puberty. (mercurynews.com)
  • A condition defined as the development of secondary sexual characteristics in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of puberty in the population. (uniprot.org)
  • It is relatively easy to track menarche [the first period]," explains Julie Deardorff, coauthor with Louise Greenspan of The New Puberty: How to Navigate Early Development in Today's Girls . (greatschools.org)
  • Treatment for precocious puberty typically includes medication to delay further development. (drugs.com)
  • The studies indicated that physiological or puberty thyroid growth was predominantly influenced by growth factors that were required for somatic development. (home-remedies-for-you.com)
  • Puberty leads to sexual dimorphism through the development of the secondary sex characteristics, which further distinguish the sexes. (wikipedia.org)
  • However the rate of conversion from testosterone to estradiol (driven by FSH/LH balance) during early puberty is highly individual, resulting in very diverse development patterns of secondary sexual characteristics. (wikipedia.org)
  • Production of progesterone in the ovaries begins with the development of ovulatory cycles in girls (during the lutheal phase of the cycle), before puberty low levels of progesterone are produced in the adrenal glands of both boys and girls. (wikipedia.org)
  • The growth spurt in thyroid which coincided in girls with menarche may have contributed to an increase in goiter during the puberty years. (home-remedies-for-you.com)
  • Records from several northern European countries, particularly Norway, Denmark, and Finland, document that the age of menarche, a convenient marker for the timing of puberty in girls, decreased from ∼16 to 17 years during the 19th century to ∼13 years by the middle of the 20th century. (aappublications.org)
  • For example, a significant delay in puberty and menarche is seen in girls who are very physically active and have markedly diminished body fat. (aappublications.org)
  • Children with early puberty are at a risk for accelerated skeletal maturation and short adult height, early sexual debut, potential sexual abuse, and psychosocial difficulties. (aappublications.org)
  • Although early physical maturation can occur in both sexes, girls are ten times more likely to undergo precocious puberty than boys. (bradley.edu)
  • Puberty usually lasts for about 3 years from onset to full maturation. (healio.com)
  • The timing of puberty is influenced by several factors in addition to genetics, including nutrition, socioeconomic status, and exposure to certain chemicals in the environment. (medlineplus.gov)
  • TUESDAY, Dec. 4, 2018 (HealthDay News) -- Exposure to chemicals found in a wide array of personal care products has been linked to early puberty among girls, a new investigation warns. (webmd.com)
  • As to how routine exposure to the chemicals might affect puberty, she said they've "been shown to mimic estrogen in certain laboratory conditions. (webmd.com)
  • Now, her team found that "the higher the levels of the chemicals in mothers' or daughters' bodies, the earlier the puberty" among girls. (webmd.com)
  • So, although we are not ready to say that early life exposure to these chemicals causes earlier puberty in girls, we have enough evidence to be concerned. (webmd.com)
  • Boys' puberty timing didn't appear to be influenced by prenatal exposure to these chemicals. (reuters.com)
  • The study wasn't designed to prove whether or how prenatal exposure to these chemicals might have caused early puberty. (reuters.com)
  • Was early puberty because of the chemicals? (news-medical.net)
  • Rather than the chemicals being the cause of the earlier puberty, it could be that children who mature faster are more likely to use cosmetics and other body care products. (news-medical.net)
  • What if these chemicals are mimicking estrogen in our bodies, making girls hit puberty earlier and putting them at risk for cancer? (cincinnatichildrens.org)
  • They want to know whether chemicals in everything from plastic food packaging to processed foods can program the timing of puberty, as well as the way girls gain weight, and set them up for more health problems. (cincinnatichildrens.org)
  • Dr Kim Harley, Associate Professor in Public Health at the University of California , Berkeley, US, who led the study, said: "We found evidence that some chemicals widely used in personal care products are associated with earlier puberty in girls. (telegraph.co.uk)
  • Specifically, we found that mothers who had higher levels of two chemicals in their bodies during pregnancy - diethyl phthalate, which is used in fragrance, and triclosan, which is an antibacterial agent in certain soaps and toothpaste - had daughters who entered puberty earlier. (telegraph.co.uk)
  • Why are people so much more willing to use strange chemicals to explain earlier puberty that other trens like increasing IQ, lifespan, and height? (overcomingbias.com)
  • Scientists have also pointed to genetics and chemicals in the environment as possible causes of early puberty. (babycenter.com)
  • Most girls get their first period when they're 12 or 13 years old, which is about 2 or 2½ years after they begin puberty. (kidshealth.org)
  • The best book on puberty for 9-15 year old boys completely updated for the first time in 12 years! (google.com)
  • Selected as a "Best Book for Young Adults" by the American Library Association--The classic puberty education book for 9-15 year-old boys (over 500,000 copies sold), now thoroughly updated and freshly redesigned for the first time in 12 years. (google.com)
  • I'm 18 years old and have hit puberty for sure because I'm 6 foot 3 and I have hair growing. (medhelp.org)
  • Abnormally early" has traditionally been defined as younger than 9 years in boys and younger than 8 years in girls, though studies undertaken since the 1990s indicate that the normal onset of puberty may be occurring at a younger age in girls in developed countries and that therefore the age of precocious puberty for girls may actually be as low as 6 or 7. (britannica.com)
  • A girl usually gets her first period between 10 and 16 years old (about 2 to 2 1/2 years after she starts puberty. (webmd.com)
  • There's less evidence that boys are entering puberty at earlier ages, although one study last year suggested boys were maturing six months to two years earlier than other studies have shown. (usatoday.com)
  • It found blacks continue to develop earlier than whites, reaching puberty at a median age of 8.8, vs. 9.3 years for Hispanics and 9.7 for Asians. (usatoday.com)
  • It was only in 2008 that the Endocrine Society approved puberty suppressors as a treatment for transgender adolescents as young as 12 years old. (businessinsider.com)
  • Puberty has changed in the last 40 years," explains Paul B. Kaplowitz, MD, PhD, Division Chief, Endocrinology at the Children's National Health System in Washington, DC. (greatschools.org)
  • The onset and progress of puberty has been the subject of my research and clinical interest over the past 28 years including my doctoral thesis (2). (bmj.com)
  • Over the past 20 years, research has shown that girls, and possibly also boys, have been going through puberty earlier and earlier. (mercurynews.com)
  • Many boys seem to change overnight, but puberty lasts months or even a few years. (infobarrel.com)
  • Puberty may happen as young as ten or as old as fifteen with the average age being twelve years. (infobarrel.com)
  • In Europe, the lower end of the normal range for the onset of puberty is 8 years in girls, although there are ethnic variations. (redorbit.com)
  • The review concludes that the decision whether to provide treatment or not is a difficult one, in particular, for girls who commence puberty between 6 and 8 years old. (redorbit.com)
  • She has been a participant in a puberty study since she was 7 years old. (sfgate.com)
  • Hitting puberty at age 7 or 8 - a couple years earlier than average - can cause long-lasting anxiety for kids. (kqed.org)
  • While the age-range for puberty varies, says Jennifer Dietrich , a pediatric gynecologist at Texas Children's Hospital, the average age of menses is 12.3 years old. (kqed.org)
  • Helping kids navigate these new social and emotional hurdles can be tricky, especially since puberty spans several years. (kqed.org)
  • Girls generally go through puberty between 10 and 12 years old, while boys are later at 12 to 14 years old. (steamboatpilot.com)
  • According to the American Academy of Family Physicians, puberty begins for girls between 8 and 14 years of age. (modernmom.com)
  • New Orleans) - A study conducted by the American Academy of Pediatrics (AAP) has documented that boys in the U.S. are experiencing the onset of puberty six months to two years earlier than reported in previous research. (aap.org)
  • Nine-year-old Mandy went through puberty when she was just two years old. (thedoctorstv.com)
  • To monitor and also communicate the progression of puberty in males and females, a staging system has been developed, called Tanner Staging but more recently referred to as the Maturity Rating Scale ( Table 1 ). (healio.com)
  • Both early and late puberty can run in families. (familydoctor.org)
  • Both early and late puberty can have physical and psychological implications for the pediatric population. (healio.com)
  • The open, non-judgmental conversations you have with your children about sex, puberty, bodies, and relationships will help them stay safe and healthy as they grow up. (plannedparenthood.org)
  • It's a tough passage for many kids, but for some - transgender youth whose bodies don't match their gender identity - puberty can be unbearable. (businessinsider.com)
  • Puberty is the time when girls' bodies and minds mature and they grow into young women. (nationwidechildrens.org)
  • We also found that girls with higher levels of parabens in their bodies at the age of nine entered puberty earlier. (telegraph.co.uk)
  • Scientists have identified mutations in a gene responsible for some cases of early puberty, an issue of growing concern to doctors, as children begin developing earlier and earlier. (usatoday.com)
  • Five of the families had mutations in a gene called MKRN3, which normally acts as a brake to keep children from entering puberty. (usatoday.com)
  • Full-blown puberty is irreversible, but for transgender children, it's no longer inevitable. (businessinsider.com)
  • Prof Najman says the findings, coupled with children reaching puberty earlier and earlier, may explain why girls are increasingly involved in anti-social behaviour such as drinking, smoking, drug-taking and bullying. (nzherald.co.nz)
  • Sometimes it seems like today's children are growing up faster than ever, and a new study published in the journal Pediatrics has found that American girls are indeed entering puberty earlier than ever before. (redorbit.com)
  • It is important to talk openly with your children about puberty. (jamaica-gleaner.com)
  • since puberty signals the bones to mature and stop growing, children who go through this process too early stop growing before they reach their full height potential. (greatschools.org)
  • To understand what causes precocious puberty in some children, it's helpful to know what causes puberty to begin. (drugs.com)
  • For the majority of children with this condition, there's no underlying medical problem and no identifiable reason for the early puberty. (drugs.com)
  • Children with "partial" early puberty may need to be seen by a doctor. (nationwidechildrens.org)
  • Children with untreated early puberty sometimes do not reach their full adult height, because their bones mature and bone growth stops too soon. (nationwidechildrens.org)
  • Even though they may have an early growth spurt that makes them taller than other children their age, finishing puberty early makes them stop growing too soon. (nationwidechildrens.org)
  • Children with precocious puberty can be treated. (nationwidechildrens.org)
  • If her doctor thinks your daughter has precocious puberty, she may be sent to a pediatric endocrinologist (a doctor who specializes in growth and hormonal disorders in children). (nationwidechildrens.org)
  • These children, however, do not necessarily meet the criteria for true precocious puberty. (rarediseases.org)
  • A provocative new research reports suggests that children who speed through puberty are more likely to act out and to suffer from anxiety and depression . (psychcentral.com)
  • Moreover, children are very knowledgeable and sensitive as to how fast or slow their friends are going through puberty. (psychcentral.com)
  • Puberty is an important process that providers of health care to children and adolescents should be comfortable discussing. (healio.com)
  • After puberty, people are able to make children. (wikipedia.org)
  • When puberty ends, growth in height stops. (kidshealth.org)
  • Because their skeletons mature and bone growth stops at an earlier age than normal, kids with precocious puberty that's not treated usually don't reach their full adult height potential. (kidshealth.org)
  • [14] Short stature, delayed growth in height and weight, and/or delayed puberty may be the only clinical manifestations of coeliac disease , in absence of any other symptoms. (wikipedia.org)
  • About a year after puberty begins, girls have a growth spurt. (webmd.com)
  • Precocious or early puberty has been linked to possible problems, including stunted growth, emotional-social problems like increased risks of depression and substance abuse. (ndtv.com)
  • Physical growth-height and weight-accelerates in the first half of puberty and is completed when an adult body has been developed. (wikipedia.org)
  • Early puberty also can stunt growth and cause behavioral problems. (eurekalert.org)
  • Puberty is initiated by hormone signals from the brain to the gonads (the ovaries and testes). (google.com)
  • Puberty begins when a gland in the brain called the hypothalamus is stimulated to release bursts of a hormone called gonadotropin releasing hormone (GnRH). (medlineplus.gov)
  • Early puberty rarely is due to hormone exposure or a problem with the thyroid, ovaries, or brain. (webmd.com)
  • Some believe the longer exposure to the hormone estradiol, associated with early puberty, can increase risks. (psychcentral.com)
  • True precocious puberty is a condition in which normal pituitary-gonadal function is activated at an abnormally early age. (britannica.com)
  • The most common physiological reason for puberty menorrhagia is the immaturity of hypothalamic-pituitary-ovarian axis, leading to inadequate positive feedback and sustained high estrogen levels. (wikipedia.org)
  • A low age at male puberty is associated with an increased risk for testicular cancer according to several, but not all, epidemiologic studies. (aappublications.org)
  • For boys, puberty begins with testicular enlargement. (healio.com)
  • U.S. girls are entering puberty at a younger age than in the past. (mercola.com)
  • While previous studies found that race as well as body mass index (BMI) played a role in predicting the onset of puberty, "BMI supplants race as the No. 1 factor" in the new analysis, says lead author Frank Biro, director of adolescent medicine at Cincinnati Children's Hospital. (usatoday.com)
  • Delayed puberty in girls is when a female adolescent whose breasts have not developed by the age of 13 and has not gotten her menstrual period by age 16. (childrens.com)
  • Most delayed puberty cases turn out perfectly fine, and the adolescent will undergo puberty at a later age. (childrens.com)
  • I practice as an adolescent endocrinologist with a special interest in disorders of puberty and currently run the only national specialist referral service for boys with Klinefelter's syndrome in the UK. (bmj.com)
  • A report in the August issue of Archives of Pediatrics and Adolescent Medicine, one of the JAMA/Archives journals says that adolescent girls who hit puberty early and have parents who spend less quality time with them are more likely be aggressive in nature. (medindia.net)
  • For boys, the size of testicles is used to gauge the advance of puberty, and for girls, the size and contour of breasts are used. (modernmom.com)