A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
Drugs used to treat or prevent skin disorders or for the routine care of skin.
A type of inflammatory arthritis associated with PSORIASIS, often involving the axial joints and the peripheral terminal interphalangeal joints. It is characterized by the presence of HLA-B27-associated SPONDYLARTHROPATHY, and the absence of rheumatoid factor.
Photochemotherapy using PSORALENS as the photosensitizing agent and ultraviolet light type A (UVA).
The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.
A by-product of the destructive distillation of coal used as a topical antieczematic. It is an antipruritic and keratoplastic agent used also in the treatment of psoriasis and other skin conditions. Occupational exposure to soots, tars, and certain mineral oils is known to be carcinogenic according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985) (Merck Index, 11th ed).
Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of ETRETINATE with the advantage of a much shorter half-life when compared with etretinate.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
Diseases of the nail plate and tissues surrounding it. The concept is limited to primates.
A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.
A medical specialty concerned with the skin, its structure, functions, diseases, and treatment.
The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).
Treatment of disease by exposure to light, especially by variously concentrated light rays or specific wavelengths.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Scalp dermatoses refer to various inflammatory skin conditions affecting the scalp, including seborrheic dermatitis, psoriasis, atopic dermatitis, and tinea capitis, often characterized by symptoms such as redness, scaling, itching, and hair loss.
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa subunit that is shared with INTERLEUKIN-12. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
'Skin diseases' is a broad term for various conditions affecting the skin, including inflammatory disorders, infections, benign and malignant tumors, congenital abnormalities, and degenerative diseases, which can cause symptoms such as rashes, discoloration, eruptions, lesions, itching, or pain.
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
Any inflammation of the skin.
A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).

Psoriatic keratinocytes show reduced IRF-1 and STAT-1alpha activation in response to gamma-IFN. (1/1954)

Psoriasis is a chronic inflammatory dermatosis characterized by hyperproliferative keratinocytes (KC). The skin lesions are infiltrated by T cells, which secrete gamma interferon (gamma-IFN) and are believed to be necessary to maintain the psoriatic phenotype. In normal KC, gamma-IFN is a potent inhibitor of proliferation, but proliferation of KC persists in psoriatic plaques despite the presence of gamma-IFN. Immunostaining of interferon regulatory factor-1 (IRF-1) revealed that IRF-1 was localized to the basal cells of the epidermis in normal and in nonlesional psoriatic skin, but was suprabasal or completely absent in lesional psoriatic skin. This finding led to the hypothesis that abnormal signaling in the gamma-IFN pathway may occur in psoriatic KC. To test this hypothesis, we measured activation of IRF-1 and signal transducer and activator of transcription (STAT)-1alpha transcription factors in KC after stimulation with gamma-IFN. Primary cultures of KC from normal and nonlesional psoriatic skin were stimulated with gamma-IFN and subsequent transcription factor activation was measured by electrophoretic mobility shift assay. Psoriatic KC showed a reduced induction of IRF-1 and STAT-1alpha activation after stimulation with gamma-IFN, compared with normal KC. Reduced activation of IRF-1 and STAT-1alpha in response to gamma-IFN indicates a fundamental defect in the growth and differentiation control of psoriatic KC in the absence of the influence of other cell types.  (+info)

Topical psoriasis therapy. (2/1954)

Psoriasis is a common dermatosis, affecting from 1 to 3 percent of the population. Until recently, the mainstays of topical therapy have been corticosteroids, tars, anthralins and keratolytics. Recently, however, vitamin D analogs, a new anthralin preparation and topical retinoids have expanded physicians' therapeutic armamentarium. These new topical therapies offer increased hope and convenience to the large patient population with psoriasis.  (+info)

Antipsoriatic, anti-inflammatory, and analgesic effects of an extract of red propolis. (3/1954)

AIM: To study the antipsoriatic, anti-inflammatory, and analgesic effects of ethanolic extract of red propolis. METHODS AND RESULTS: This extract induced the formation of granular layer in the mouse tail test used as a model of psoriasis. Propolis 50 mg.kg-1 i.g. showed anti-inflammatory activity in the cotton-pellet granuloma assay in rats, in croton oil-induced edema in mice at a dose of 25% (2.5 microL), and in the peritoneal capillary permeability test in mice at a dose of 10 mg.kg-1. The extract (25 mg.kg-1 i.g.) showed analgesic effect in the model of acetic acid-induced writhings, whereas 40 mg.kg-1 was effective in the hot plate test in mice. CONCLUSION: Anti-inflammatory, analgesic, and antipsoriatric properties of Cuban red propolis were evident.  (+info)

A susceptibility locus for epidermodysplasia verruciformis, an abnormal predisposition to infection with the oncogenic human papillomavirus type 5, maps to chromosome 17qter in a region containing a psoriasis locus. (4/1954)

Epidermodysplasia verruciformis (EV) is a rare genodermatosis characterized by an abnormal susceptibility to infection with a specific group of related human papillomavirus (HPV) genotypes, including the oncogenic HPV5 associated with the skin carcinomas developing in about half of EV patients. EV is usually considered as an autosomal recessive condition. Taking EV as a model to identify a locus underlying the susceptibility to HPV infections, we performed a genome-wide search for linkage with 255 microsatellite genetic markers in three consanguineous EV families comprising six patients, using the homozygosity mapping approach. Homozygosity restricted to affected individuals was observed for a marker of chromosome 17q (D17S784) in two families and a marker about 17 centiMorgan (cM) distal (D17S1807) in the third family. Ten additional microsatellite markers spanning 29 cM in this region were analyzed. Two-point lod score values greater than 3 were obtained for four markers and multipoint linkage analysis yielded a maximum lod score of 10.17 between markers D17S939 and D17S802. Recombination events observed in two families allowed a candidate region for the EV susceptibility locus to be mapped to the 1 cM region defined by these two markers. The EV locus (named EV1) is included in the 17qter region recently found to contain a dominant locus for the susceptibility to familial psoriasis. It has been shown that patients suffering from psoriasis are likely to constitute the reservoir of HPV5. It is thus tempting to speculate that distinct defects affecting the same gene may be involved in the two skin conditions.  (+info)

Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium. (5/1954)

In epidermis, it has been suggested, intercellular communication through gap junctions is important in coordinating cell behavior. The connexins, may facilitate selective assembly or permeability of gap junctions, influencing the distribution of metabolites between cells. Using immunohistochemistry, we have compared the distribution of connexins 26 and 43 with that of proliferating cells (Ki67 labeling) in normal epidermis, hyperplastic epidermis (tape-stripped epidermis, psoriatic lesions, and viral warts), and vaginal and buccal epithelia. Connexin 43 was abundant in spinous layers of all epidermal specimens and in vaginal and buccal epithelia. Connexin 26 was absent from the interfollicular and interductal epidermis of normal hair-bearing skin, and nonlesional psoriatic epidermis but present at very low levels in plantar epidermis. Connexin 26 was prominent in lesional psoriatic epidermis and viral warts and in vaginal and buccal epithelia. In three independent experiments connexin 26 appeared in a patchy intercellular distribution in the basal epidermis within 24 h of tape stripping, proceeding to more extensive distribution in basal and suprabasal layers by 48 h. The increase in connexin 26 preceded that in cell proliferation. In vaginal epithelium, buccal epithelium, and viral warts connexin 26 was restricted mainly to suprabasal, nonproliferating cells. In psoriatic lesional epidermis connexin 26 was also located mainly in suprabasal, nonproliferating cells. Connexin 26 was present in a patchy distribution in the basal layer of psoriatic lesional epidermis, but double labeling for connexin 26 and Ki67 showed that many connexin 26 positive basal cells were nonproliferative, suggesting that connexin 26 may be related to differentiation rather than to proliferation. These observations would be consistent with a role for connexin 26 containing gap junctions during both early and later stages of keratinocyte differentiation in hyperplastic epidermis and in vaginal and buccal epithelia.  (+info)

Optimum porphyrin accumulation in epithelial skin tumours and psoriatic lesions after topical application of delta-aminolaevulinic acid. (6/1954)

Photodynamic therapy with topically applied delta-aminolaevulinic acid is used to treat skin tumours by employing endogenously formed porphyrins as photosensitizers. This study examines the time course of porphyrin metabolite formation after topical application of delta-aminolaevulinic acid. Porphyrin biosynthesis in human skin tumours (basal cell carcinoma, squamous cell carcinoma), in psoriatic lesions, and in normal skin was investigated. Skin areas were treated with delta-aminolaevulinic acid, and levels of total porphyrins, porphyrin metabolites and proteins were measured in samples excised after 1, 2, 4, 6, 9, 12 and 24 h. There was an increase in porphyrin biosynthesis in all tissues with maximum porphyrin levels in tumours between 2 and 6 h and in psoriatic lesions 6 h after treatment. The pattern of porphyrins showed no significant difference between normal and neoplastic skin, protoporphyrin being the predominant metabolite. The results suggest that optimum irradiation time for superficial epithelial skin tumours may be as soon as 2 h after application of delta-aminolaevulinic acid, whereas for treatment of psoriatic lesions an application time of 6 h is more suitable.  (+info)

Calcium-binding protein S100A7 and epidermal-type fatty acid-binding protein are associated in the cytosol of human keratinocytes. (7/1954)

Expression of epidermal-type fatty acid-binding protein (E-FABP) and S100A7 has previously been shown to be elevated in psoriatic skin, a disease characterized by abnormal keratinocyte differentiation. However, no causal relationship between the up-regulation of these proteins and the disease has been shown. E-FABP is thought to be involved in cytosolic fatty acid (FA) transport, whereas the role of S100A7 is still unknown. In this report, we show by overlay assays that E-FABP, immobilized on nitrocellulose, is able to capture S100A7 from cytosolic psoriatic protein extracts and vice versa, suggesting the formation of a complex between the two proteins. Using purified E-FABP and S100A7, the complex can be reconstituted only in presence of EDTA. Moreover, we show that increased EDTA concentrations in psoriatic cytosolic protein extracts enhance complex formation. Partial complex disruption was obtained by the addition of physiological concentrations of Zn2+ (0.1 mM), whereas Ca2+ at 5 mM and Mg2+ at 30 mM had no effect. On the other hand, high Ca2+ concentrations (30 mM) resulted in partial complex disruption. Oleic acid-binding properties were observed for free E-FABP and the complex E-FABP-S100A7, but not for free S100A7. By using confocal microscopy we show that S100A7 and E-FABP are co-localized in the cytoplasm of differentiating keratinocytes from lesional psoriatic skin. These data indicate that formation of the E-FABP-S100A7 complex and its FA-binding function might be regulated at least by bivalent cations.  (+info)

Does psychological intervention help chronic skin conditions? (8/1954)

The objective of the study was to assess the impact of psychological/psychiatric assessment in patients with chronic or intractable dermatological conditions. A diagnostic interview was undertaken in order to pin-point any temporal connection between an adverse life-event and the first appearance of the skin disorder. Following this, the dermatologist's assessment of subsequent changes in the skin disorder were noted. The three main dermatological diagnoses were atopic eczema (10), prurigo (10), and psoriasis (nine). Follow-up was for up to 5 years. A favourable response was noted in 40 out of the 64 patients who participated in the study; this was usually evident within a few weeks and maintained thereafter. Remission was achieved in 12, while 28 showed some improvement. We conclude that this liaison between dermatology and psychiatry proved a valuable adjunct to normal dermatological treatment and was followed by improvement in the majority of patients.  (+info)

Psoriasis is a chronic skin disorder that is characterized by recurrent episodes of red, scaly patches on the skin. The scales are typically silvery-white and often occur on the elbows, knees, scalp, and lower back, but they can appear anywhere on the body. The exact cause of psoriasis is unknown, but it is believed to be related to an immune system issue that causes skin cells to grow too quickly.

There are several types of psoriasis, including plaque psoriasis (the most common form), guttate psoriasis, inverse psoriasis, pustular psoriasis, and erythrodermic psoriasis. The symptoms and severity of the condition can vary widely from person to person, ranging from mild to severe.

While there is no cure for psoriasis, various treatments are available that can help manage the symptoms and improve quality of life. These may include topical medications, light therapy, and systemic medications such as biologics. Lifestyle measures such as stress reduction, quitting smoking, and avoiding triggers (such as certain foods or alcohol) may also be helpful in managing psoriasis.

Dermatologic agents are medications, chemicals, or other substances that are applied to the skin (dermis) for therapeutic or cosmetic purposes. They can be used to treat various skin conditions such as acne, eczema, psoriasis, fungal infections, and wounds. Dermatologic agents include topical corticosteroids, antibiotics, antifungals, retinoids, benzoyl peroxide, salicylic acid, and many others. They can come in various forms such as creams, ointments, gels, lotions, solutions, and patches. It is important to follow the instructions for use carefully to ensure safety and effectiveness.

Psoriatic arthritis is a form of inflammatory arthritis that occurs in some people with psoriasis, a skin condition characterized by scaly, red, and itchy patches. The Arthritis Foundation defines psoriatic arthritis as "a chronic disease characterized by swelling, pain, and stiffness in and around the joints. It usually affects the fingers and toes but can also affect the lower back, knees, ankles, and spine."

Psoriatic arthritis can cause a variety of symptoms, including:

* Joint pain, swelling, and stiffness
* Swollen fingers or toes (dactylitis)
* Tenderness, pain, and swelling where tendons and ligaments attach to bones (enthesitis)
* Changes in nail growth, such as pitting, ridging, or separation from the nail bed
* Fatigue and weakness
* Reduced range of motion and mobility

The exact cause of psoriatic arthritis is not fully understood, but it is believed to involve a combination of genetic, environmental, and immune system factors. Treatment typically involves a combination of medications, lifestyle changes, and physical therapy to manage symptoms and prevent joint damage.

PUVA therapy is a type of treatment that uses both medication and light to treat certain skin conditions, such as psoriasis, eczema, and cutaneous T-cell lymphoma. The name "PUVA" stands for Psoralen + UVA, which refers to the two main components of the therapy:

1. Psoralen: This is a medication that makes the skin more sensitive to light. It can be taken orally or applied directly to the skin in the form of a cream or bath.
2. UVA: This stands for Ultraviolet A, which is a type of light that is part of the natural sunlight spectrum. In PUVA therapy, the skin is exposed to a controlled dose of UVA light in a special booth or room.

When psoralen is introduced into the body, it absorbs into the skin and makes it more sensitive to UVA light. When the skin is then exposed to UVA light, it triggers a chemical reaction that slows down the growth of affected skin cells. This helps to reduce inflammation, scaling, and other symptoms associated with the skin condition being treated.

It's important to note that PUVA therapy can have side effects, including sunburn, itching, redness, and an increased risk of skin cancer over time. As such, it is typically used as a second-line treatment when other therapies have not been effective, and it is closely monitored by a healthcare professional to ensure its safe and effective use.

Ultraviolet (UV) therapy, also known as phototherapy, is a medical treatment that uses ultraviolet light to treat various skin conditions. The UV light can be delivered through natural sunlight or artificial sources, such as specialized lamps or lasers.

In medical settings, controlled doses of UV light are used to target specific areas of the skin. The most common type of UV therapy is narrowband UVB (NB-UVB) phototherapy, which uses a specific wavelength of UVB light to treat conditions such as psoriasis, eczema, vitiligo, and dermatitis.

The goal of UV therapy is to reduce inflammation, slow skin cell growth, and improve the overall appearance of the skin. It is important to note that while UV therapy can be effective in treating certain skin conditions, it also carries risks such as skin aging and an increased risk of skin cancer. Therefore, it should only be administered under the supervision of a qualified healthcare professional.

Coal tar is a thick, dark liquid that is a byproduct of coal manufacturing processes, specifically the distillation of coal at high temperatures. It is a complex mixture of hundreds of different compounds, including polycyclic aromatic hydrocarbons (PAHs), which are known to be carcinogenic.

In medical terms, coal tar has been used topically for various skin conditions such as psoriasis, eczema, and seborrheic dermatitis due to its anti-inflammatory and keratolytic properties. Coal tar can help reduce scaling, itching, and inflammation of the skin. However, its use is limited due to potential side effects such as skin irritation, increased sun sensitivity, and potential risk of cancer with long-term use. Coal tar products should be used under the guidance of a healthcare provider and according to the instructions on the label.

HLA-C antigens are a type of human leukocyte antigen (HLA) found on the surface of cells in the human body. They are part of the major histocompatibility complex (MHC) class I molecules, which play a critical role in the immune system's ability to differentiate between "self" and "non-self" cells.

HLA-C antigens are responsible for presenting peptide fragments from inside the cell to CD8+ T cells, also known as cytotoxic T lymphocytes (CTLs). This presentation allows the CTLs to recognize and destroy infected or damaged cells, helping to prevent the spread of viruses and other pathogens.

Like other HLA antigens, HLA-C antigens are highly polymorphic, meaning that there are many different variations of these molecules in the human population. This diversity allows for a better match between an individual's immune system and the pathogens they encounter, increasing the chances of mounting an effective immune response. However, this same diversity can also make it more challenging to find compatible organ donors for transplantation.

Acitretin is a synthetic form of retinoic acid, which is a type of vitamin A. It is used to treat severe psoriasis and other skin conditions. Acitretin works by slowing down the rapid growth of skin cells that cause the symptoms of psoriasis. It comes in the form of a capsule and is taken orally.

Common side effects of acitretin include dryness of the skin, lips, and mouth, itching, peeling, redness, or stickiness of the palms and soles, hair loss, and changes in nail growth. Less common but more serious side effects can include liver damage, increased levels of lipids in the blood, and birth defects if taken during pregnancy.

It is important to note that acitretin can cause birth defects, so women who are pregnant or planning to become pregnant should not take this medication. Additionally, because acitretin can remain in the body for a long time, it is recommended that women of childbearing age use effective contraception while taking this medication and for at least three years after stopping it.

In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.

Anthralin is a medication that is used to treat chronic plaque psoriasis. It is a synthetic form of a substance found in the bark of the araroba tree, which has been used traditionally in folk medicine to treat skin conditions. Anthralin works by slowing down the growth of skin cells, reducing inflammation, and helping to flake off scales.

Anthralin is available in various forms, including creams, ointments, and pastes, and is usually applied directly to the affected areas of the skin for a short period of time, typically ranging from 10 to 30 minutes, once or twice a day. It may take several weeks of regular use to see improvement in symptoms.

Anthralin can cause skin irritation, so it's important to follow your healthcare provider's instructions carefully when using this medication. You should also avoid applying anthralin to healthy skin and wash your hands thoroughly after each application to prevent accidentally transferring the medication to other parts of your body.

Keratolytic agents are substances that cause the softening and sloughing off of excess keratin, the protein that makes up the outermost layer of the skin (stratum corneum). These agents help to break down and remove dead skin cells, increase moisture retention, and promote the growth of new skin cells. They are commonly used in the treatment of various dermatological conditions such as psoriasis, eczema, warts, calluses, and ichthyosis. Examples of keratolytic agents include salicylic acid, urea, lactic acid, and retinoic acid.

Keratinocytes are the predominant type of cells found in the epidermis, which is the outermost layer of the skin. These cells are responsible for producing keratin, a tough protein that provides structural support and protection to the skin. Keratinocytes undergo constant turnover, with new cells produced in the basal layer of the epidermis and older cells moving upward and eventually becoming flattened and filled with keratin as they reach the surface of the skin, where they are then shed. They also play a role in the immune response and can release cytokines and other signaling molecules to help protect the body from infection and injury.

Nail diseases, also known as onychopathies, refer to a group of medical conditions that affect the nail unit, which includes the nail plate, nail bed, lunula, and surrounding skin (nail fold). These diseases can be caused by various factors such as fungal infections, bacterial infections, viral infections, systemic diseases, trauma, and neoplasms.

Some common examples of nail diseases include:

1. Onychomycosis - a fungal infection that affects the nail plate and bed, causing discoloration, thickening, and crumbling of the nail.
2. Paronychia - an infection or inflammation of the nail fold, caused by bacteria or fungi, resulting in redness, swelling, and pain.
3. Ingrown toenails - a condition where the nail plate grows into the surrounding skin, causing pain, redness, and infection.
4. Onycholysis - a separation of the nail plate from the nail bed, often caused by trauma or underlying medical conditions.
5. Psoriasis - a systemic disease that can affect the nails, causing pitting, ridging, discoloration, and onycholysis.
6. Lichen planus - an inflammatory condition that can affect the skin and nails, causing nail thinning, ridging, and loss.
7. Melanonychia - a darkening of the nail plate due to pigmentation, which can be benign or malignant.
8. Brittle nails - a condition characterized by weak, thin, and fragile nails that easily break or split.
9. Subungual hematoma - a collection of blood under the nail plate, often caused by trauma, resulting in discoloration and pain.
10. Tumors - abnormal growths that can develop in or around the nail unit, ranging from benign to malignant.

Accurate diagnosis and treatment of nail diseases require a thorough examination and sometimes laboratory tests, such as fungal cultures or skin biopsies. Treatment options vary depending on the underlying cause and may include topical or oral medications, surgical intervention, or lifestyle modifications.

Clobetasol is a topical corticosteroid medication that is used to reduce inflammation and relieve itching, redness, and swelling associated with various skin conditions. It works by suppressing the immune system's response to reduce inflammation. Clobetasol is available in several forms, including creams, ointments, emulsions, and foams, and is usually applied to the affected area once or twice a day.

It is important to use clobetasol only as directed by a healthcare provider, as prolonged or excessive use can lead to thinning of the skin, increased susceptibility to infections, and other side effects. Additionally, it should not be used on large areas of the body or for extended periods without medical supervision.

Dermatology is a medical specialty that focuses on the diagnosis, treatment, and prevention of diseases and conditions related to the skin, hair, nails, and mucous membranes. A dermatologist is a medical doctor who has completed specialized training in this field. They are qualified to treat a wide range of skin conditions, including acne, eczema, psoriasis, skin cancer, and many others. Dermatologists may also perform cosmetic procedures to improve the appearance of the skin or to treat signs of aging.

The epidermis is the outermost layer of the skin, composed mainly of stratified squamous epithelium. It forms a protective barrier that prevents water loss and inhibits the entry of microorganisms. The epidermis contains no blood vessels, and its cells are nourished by diffusion from the underlying dermis. The bottom-most layer of the epidermis, called the stratum basale, is responsible for generating new skin cells that eventually move up to replace dead cells on the surface. This process of cell turnover takes about 28 days in adults.

The most superficial part of the epidermis consists of dead cells called squames, which are constantly shed and replaced. The exact rate at which this happens varies depending on location; for example, it's faster on the palms and soles than elsewhere. Melanocytes, the pigment-producing cells, are also located in the epidermis, specifically within the stratum basale layer.

In summary, the epidermis is a vital part of our integumentary system, providing not only physical protection but also playing a crucial role in immunity and sensory perception through touch receptors called Pacinian corpuscles.

Phototherapy is a medical treatment that involves the use of light to manage or improve certain conditions. It can be delivered in various forms, such as natural light exposure or artificial light sources, including lasers, light-emitting diodes (LEDs), or fluorescent lamps. The wavelength and intensity of light are carefully controlled to achieve specific therapeutic effects.

Phototherapy is most commonly used for newborns with jaundice to help break down bilirubin in the skin, reducing its levels in the bloodstream. This type of phototherapy is called bilirubin lights or bili lights.

In dermatology, phototherapy can be applied to treat various skin conditions like psoriasis, eczema, vitiligo, and acne. Narrowband ultraviolet B (UVB) therapy, PUVA (psoralen plus UVA), and blue or red light therapies are some examples of dermatological phototherapies.

Phototherapy can also be used to alleviate symptoms of seasonal affective disorder (SAD) and other mood disorders by exposing patients to bright artificial light, which helps regulate their circadian rhythms and improve their mood. This form of phototherapy is called light therapy or bright light therapy.

It's essential to consult a healthcare professional before starting any phototherapy treatment, as inappropriate use can lead to adverse effects.

A Severity of Illness Index is a measurement tool used in healthcare to assess the severity of a patient's condition and the risk of mortality or other adverse outcomes. These indices typically take into account various physiological and clinical variables, such as vital signs, laboratory values, and co-morbidities, to generate a score that reflects the patient's overall illness severity.

Examples of Severity of Illness Indices include the Acute Physiology and Chronic Health Evaluation (APACHE) system, the Simplified Acute Physiology Score (SAPS), and the Mortality Probability Model (MPM). These indices are often used in critical care settings to guide clinical decision-making, inform prognosis, and compare outcomes across different patient populations.

It is important to note that while these indices can provide valuable information about a patient's condition, they should not be used as the sole basis for clinical decision-making. Rather, they should be considered in conjunction with other factors, such as the patient's overall clinical presentation, treatment preferences, and goals of care.

Scalp dermatoses refer to various skin conditions that affect the scalp. These can include inflammatory conditions such as seborrheic dermatitis (dandruff, cradle cap), psoriasis, atopic dermatitis (eczema), and lichen planus; infectious processes like bacterial folliculitis, tinea capitis (ringworm of the scalp), and viral infections; as well as autoimmune conditions such as alopecia areata. Symptoms can range from mild scaling and itching to severe redness, pain, and hair loss. The specific diagnosis and treatment of scalp dermatoses depend on the underlying cause.

Interleukin-23 (IL-23) is a pro-inflammatory cytokine, which is a type of signaling molecule used for communication between cells in the immune system. It is a heterodimeric protein composed of two subunits: p19 and p40. IL-23 plays a crucial role in the adaptive immune response by promoting the differentiation and activation of T-cells, particularly Th17 cells, which are involved in inflammatory responses.

IL-23 is produced primarily by activated dendritic cells and macrophages in response to various stimuli such as pathogens or tissue damage. Dysregulation of IL-23 has been implicated in several autoimmune diseases, including psoriasis, inflammatory bowel disease, rheumatoid arthritis, and multiple sclerosis. Therefore, therapeutic strategies targeting IL-23 are being explored as potential treatments for these conditions.

Atopic dermatitis is a chronic, inflammatory skin condition that is commonly known as eczema. It is characterized by dry, itchy, and scaly patches on the skin that can become red, swollen, and cracked over time. The condition often affects the skin on the face, hands, feet, and behind the knees, and it can be triggered or worsened by exposure to certain allergens, irritants, stress, or changes in temperature and humidity. Atopic dermatitis is more common in people with a family history of allergies, such as asthma or hay fever, and it often begins in infancy or early childhood. The exact cause of atopic dermatitis is not fully understood, but it is thought to involve a combination of genetic and environmental factors that affect the immune system and the skin's ability to maintain a healthy barrier function.

Skin diseases, also known as dermatological conditions, refer to any medical condition that affects the skin, which is the largest organ of the human body. These diseases can affect the skin's function, appearance, or overall health. They can be caused by various factors, including genetics, infections, allergies, environmental factors, and aging.

Skin diseases can present in many different forms, such as rashes, blisters, sores, discolorations, growths, or changes in texture. Some common examples of skin diseases include acne, eczema, psoriasis, dermatitis, fungal infections, viral infections, bacterial infections, and skin cancer.

The symptoms and severity of skin diseases can vary widely depending on the specific condition and individual factors. Some skin diseases are mild and can be treated with over-the-counter medications or topical creams, while others may require more intensive treatments such as prescription medications, light therapy, or even surgery.

It is important to seek medical attention if you experience any unusual or persistent changes in your skin, as some skin diseases can be serious or indicative of other underlying health conditions. A dermatologist is a medical doctor who specializes in the diagnosis and treatment of skin diseases.

Topical administration refers to a route of administering a medication or treatment directly to a specific area of the body, such as the skin, mucous membranes, or eyes. This method allows the drug to be applied directly to the site where it is needed, which can increase its effectiveness and reduce potential side effects compared to systemic administration (taking the medication by mouth or injecting it into a vein or muscle).

Topical medications come in various forms, including creams, ointments, gels, lotions, solutions, sprays, and patches. They may be used to treat localized conditions such as skin infections, rashes, inflammation, or pain, or to deliver medication to the eyes or mucous membranes for local or systemic effects.

When applying topical medications, it is important to follow the instructions carefully to ensure proper absorption and avoid irritation or other adverse reactions. This may include cleaning the area before application, covering the treated area with a dressing, or avoiding exposure to sunlight or water after application, depending on the specific medication and its intended use.

A phenotype is the physical or biochemical expression of an organism's genes, or the observable traits and characteristics resulting from the interaction of its genetic constitution (genotype) with environmental factors. These characteristics can include appearance, development, behavior, and resistance to disease, among others. Phenotypes can vary widely, even among individuals with identical genotypes, due to differences in environmental influences, gene expression, and genetic interactions.

Dermatitis is a general term that describes inflammation of the skin. It is often characterized by redness, swelling, itching, and tenderness. There are many different types of dermatitis, including atopic dermatitis (eczema), contact dermatitis, seborrheic dermatitis, and nummular dermatitis.

Atopic dermatitis is a chronic skin condition that often affects people with a family history of allergies, such as asthma or hay fever. It typically causes dry, scaly patches on the skin that can be extremely itchy.

Contact dermatitis occurs when the skin comes into contact with an irritant or allergen, such as poison ivy or certain chemicals. This type of dermatitis can cause redness, swelling, and blistering.

Seborrheic dermatitis is a common condition that causes a red, itchy rash, often on the scalp, face, or other areas of the body where oil glands are located. It is thought to be related to an overproduction of oil by the skin's sebaceous glands.

Nummular dermatitis is a type of eczema that causes round, coin-shaped patches of dry, scaly skin. It is more common in older adults and often occurs during the winter months.

Treatment for dermatitis depends on the underlying cause and severity of the condition. In some cases, over-the-counter creams or lotions may be sufficient to relieve symptoms. Prescription medications, such as corticosteroids or immunosuppressants, may be necessary in more severe cases. Avoiding triggers and irritants can also help prevent flare-ups of dermatitis.

Rosacea is a chronic skin condition primarily characterized by persistent redness, inflammation, and visible blood vessels on the face, particularly the nose, cheeks, forehead, and chin. It can also cause small, red, pus-filled bumps. Rosacea typically affects adults between 30 and 50 years old, with fair skin types being more susceptible. The exact cause of rosacea is unknown, but it's believed to be a combination of genetic and environmental factors, including abnormal facial blood vessels, immune system issues, and certain triggers (such as sun exposure, emotional stress, hot or cold weather, heavy exercise, alcohol consumption, spicy foods, and certain skin care products). There is no cure for rosacea, but various treatments can help control its symptoms and improve the appearance of the skin. These may include topical medications, oral antibiotics, laser therapy, and lifestyle modifications to avoid triggers.

Plaques of psoriasis A person's arm covered with plaque psoriasis Psoriasis of the palms Additional types of psoriasis comprise ... Seborrheic-like psoriasis is a common form of psoriasis with clinical aspects of psoriasis and seborrheic dermatitis, and it ... Psoriasis vulgaris (also known as chronic stationary psoriasis or plaque-like psoriasis) is the most common form and affects 85 ... the Psoriasis Association in the United Kingdom, and Psoriasis Australia offer advocacy and education about psoriasis in their ...
... , or psoriasis in the diaper area, is characteristically seen in infants between two and eight months of age.: ... ISBN 0-7216-2921-0. v t e (All stub articles, Cutaneous condition stubs, Psoriasis, Diapers). ... 194 Psoriasis Skin lesion James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical ...
Generalized pustular psoriasis (GPP) is also known as (von Zumbusch) acute generalized pustular psoriasis in acute cases, and ... GPP is a rare and severe form of psoriasis that may require hospitalization. This form of psoriasis is characterized by an ... Pustular psoriasis is classified into two major forms: localized and generalized pustular psoriasis. Within these two ... generalized pustular psoriasis). However, all forms of pustular psoriasis share in common the presence of red and tender ...
... (also known as eruptive psoriasis) is a type of psoriasis that presents as small (0.5-1.5 cm in diameter) ... Guttate psoriasis accounts for approximately 2% of psoriasis cases. The rash of guttate psoriasis on a 66-year-old male ... The treatments used for plaque psoriasis can also be used for guttate psoriasis. Few studies have specifically focused on ... "How great is the risk of further psoriasis following a single episode of acute guttate psoriasis?". Archives of Dermatology. ...
... or flexural psoriasis is a form of psoriasis that selectively, and often exclusively, involves the folds, ... Psoriasis Skin lesion James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology ... ISBN 0-7216-2921-0. v t e (Articles with short description, Short description matches Wikidata, Psoriasis, All stub articles, ...
The National Psoriasis Foundation (NPF) focuses on improving the health of people with psoriasis and psoriatic arthritis. ... The National Psoriasis Foundation provides people with psoriasis and psoriatic arthritis and their healthcare providers the ... "Executive Staff". National Psoriasis Foundation. Retrieved July 22, 2016. "NPF Discovery Grants". "National Psoriasis ... In August 2015, the National Psoriasis Foundation hosted its inaugural Team NPF Cycle event. The National Psoriasis Foundation ...
... (GPP) is an extremely rare type of psoriasis that can present in a variety of forms. Unlike the ... Pso+ represents patients with a personal history of psoriasis and pso- represents patients with no history of psoriasis. They ... Eugene M. Farber, MD and colleagues provide a description of von Zumbusch psoriasis in "Pustular Psoriasis", published in Cutis ... Most cases of generalized pustular psoriasis present in patients with existing or prior psoriasis conditions. However, there ...
... is a skin condition characterized by psoriasis with an overlapping seborrheic dermatitis.: 193 ... ISBN 0-7216-2921-0. v t e (Articles with short description, Short description is different from Wikidata, Psoriasis, All stub ... Psoriasis Skin lesion List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology ...
... is a skin condition characterized by an acute eruption of small pustules, abruptly appearing ... Psoriasis List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume ... ISBN 978-1-4160-2999-1. v t e (Articles with short description, Short description matches Wikidata, Psoriasis, All stub ...
... presents as two distinct conditions that must be considered separate from generalized psoriasis, ... ISBN 0-07-138076-0. v t e (Articles with short description, Short description matches Wikidata, Psoriasis, All stub articles, ... 411 Psoriasis Skin lesion Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ...
... is a rare variant of pustular psoriasis, having an annular, or circinate, lesion morphology that may ... ISBN 978-1-4160-2999-1. v t e (Articles with short description, Short description matches Wikidata, Psoriasis, All stub ... appear at the onset of pustular psoriasis, with a tendency to spread and form enlarged rings.: 411 Psoriasis List of cutaneous ...
Langley RG, Ellis CN: Evaluating psoriasis with Psoriasis Area and Severity Index, Psoriasis Global Assessment, and Lattice ... Psoriasis Area and Severity Index (PASI) is the most widely used tool for the measurement of severity of psoriasis. PASI ... While higher PASI scores indicate more severe psoriasis, it is difficult for patients or doctors to describe the clinical ... Amst.), 2006;44(1):21-7. Louden BA, Pearce DJ, Lang W, Feldman SR (2004). "A Simplified Psoriasis Area Severity Index (SPASI) ...
"Psoriasis: management of psoriasis" (PDF). Nice.org.uk. National Institute for Health and Clinical Excellence. Archived from ... The Psoriasis Index of Quality of Life (PSORIQoL) is a patient-reported outcome measure which determines the quality of life of ... The Psoriasis Index of Quality of Life (PSORIQOL) was published in 2003 by Galen Research. The development of the PSORIQOL was ... The PSORIQoL was then completed by two new samples of psoriasis patients by mail, in order to confirm validity and reliability ...
von Zumbusch (acute) generalized pustular psoriasis (acute GPP) is the most severe form of generalized pustular psoriasis, and ... "Treatment of pustular psoriasis: from the Medical Board of the National Psoriasis Foundation". Journal of the American Academy ... Zumbusch, Leo Ritter von (1909-02-01). "Psoriasis und pustulöses Exanthem". Archiv für Dermatologie und Syphilis (in German). ... CS1: Julian-Gregorian uncertainty, CS1 German-language sources (de), Psoriasis). ...
February 2009). "Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways". Nature Genetics. 41 (2 ... Psoriasis; Psoriatic arthritis; Systemic Lupus Erythematosus Type-1 autoimmune hepatitis Lupus nephritis TNIP1 dysfunction or ...
Psoriasis. The Psoriasis Index of Quality of Life (PSORIQOL) was the first psoriasis specific quality of life questionnaire. It ... "Psoriasis: management of psoriasis" (PDF). NICE.org.uk. National Institute for Health and Care Excellence. Archived from the ... McKenna SP, Lebwohl M, Kahler KN (June 2005). "Development of the US PSORIQoL: a psoriasis-specific measure of quality of life ... Bostoen J, Bracke S, De Keyser S, Lambert J (November 2012). "An educational programme for patients with psoriasis and atopic ...
A subtype of psoriasis, an autoimmune disease, is inverse psoriasis in which red patches can appear in the skin folds of the ... Weigle, N; McBane, S (1 May 2013). "Psoriasis". American Family Physician. 87 (9): 626-33. PMID 23668525. Dudley, Lynn M; ...
Psoriasis. Aloe extract cream might reduce redness, scaling, itching and inflammation caused by mild to moderate psoriasis. You ...
It was used during the 19th century to treat lepra vulgaris and psoriasis in humans, taken internally. Budavari, Susan (1989 ... Henry G. Piffard (1881). "Psoriasis Treatment. Part 6". A Treatise On The Materia Medica And Therapeutics Of The Skin. Sampson ... "Good Results of Donovan's Solution in Psoriasis". The Lancet. 70 (1770): 116. August 1857. doi:10.1016/S0140-6736(02)38789-0. ( ...
"CariDee". Psoriasis.org. Archived from the original on 2008-12-04. National Psoriasis Foundation (March 27, 2020). "@ ... She was also featured in the Canadian Psoriasis Education website. The National Psoriasis Foundation has removed English from ... She is a former spokesperson for the National Psoriasis Foundation. In 2007, she was spreading awareness about psoriasis and ... "Psoriasis awareness is very important to me. I want others with the disease to know they are not alone. I want to inspire them ...
It is prescribed for psoriasis and atopic dermatitis, among other conditions. With respect to potency, it is regarded as a ... "Topical Steroids Potency Chart". psoriasis.org. "Diflorasone topical". Drugs.com. "Diflorasone diacetate". Drug Information ... in moderate-severe plaque-type psoriasis". Dermatology. 186 (2): 129-32. doi:10.1159/000247323. PMID 8428041. " ...
"National Psoriasis Foundation". psoriasis.org. Archived from the original on 13 June 2010. Retrieved 16 March 2018. "Psoriasis ... Common skin conditions treated by retinoids include acne and psoriasis. Retinoids are used in the treatment of many diverse ... psoriasis), photoaging, and skin wrinkles. Isotretinoin was originally a chemotherapy treatment for certain cancers, such as ...
"About biologics". National Psoriasis Foundation. 2006-11-01. Archived from the original on 2006-01-01. Retrieved 2007-12-17. ( ...
Managing Your Psoriasis. "Master Media", Google Books. Psoriasis: Retinoids, Second Edition. "Taylor & Francis", Google Books. ... Marcel Dekker 1992 Practical Psoriasis Therapy, 2nd Edition, Mosby YearBook, New York. 1993 Managing Your Psoriasis, Master ... He was appointed to the Medical Advisory Board of the National Psoriasis Foundation in the US.[citation needed] In the 1980s, ... Psoriasis: A Patient's Guide, Third Edition. "Taylor & Francis", Google Books. (CS1 maint: multiple names: authors list, ...
"Psoriasis International Network - Psoriasis: Consensus and controversies". Archived from the original on 20 March 2012. ... Dubertret L. Psoriasis. 1993 (published in French, English and Italian) ISED Éditions du Dôme. Dubertret L, Santus R, Morlière ... Dubertret L. Psoriasis: Consensus and controversies, 2006 (online book with expert comments) Dubertret L. Soleil et santé, ... This quantitative and dynamic approach to the in vivo inflammation in humans contributed to a better understanding of psoriasis ...
Psoriasis is a skin condition characterized by the rapid buildup of skin cells, leading to scaling on the skin's surface. ... Some individuals with psoriasis also develop psoriatic arthritis, which causes joint pain, stiffness, and swelling. Systemic ... "Psoriasis - Psoriatic Arthritis". National Library of Medicine. 2019-02-20. Retrieved 2023-06-25. "Psoriatic Arthritis". ... psoriasis, rheumatoid arthritis, and systemic lupus erythematosus. Diagnosing autoimmune diseases can be challenging due to ...
April 1990). "Sulfasalazine improves psoriasis. A double-blind analysis". Archives of Dermatology. 126 (4): 487-493. doi: ... Sulfasalazine has been studied in cirrhosis, psoriasis, idiopathic urticaria, and amyloidosis. "Sulfasalazine Use During ...
57-82 [63]. ISBN 978-84-475-3285-8. National Psoriasis Foundation (2001-12-03). "The battle to save coal tar in California". ... www.psoriasis.org. Archived from the original on 2002-10-29. Retrieved 2023-06-29. U.S. Food and Drug Administration (2015-04- ... though coal tar in low concentrations is used as a topical medicine for conditions such as psoriasis. Coal and petroleum tar ... 01). "Drug Products for the Control of Dandruff, Seborrheic Dermatitis, and Psoriasis". www.accessdata.fda.gov. Archived from ...
Krell J (2006). "Use of alefacept and etanercept in 3 patients whose psoriasis failed to respond to etanercept". J Am Acad ... Alefacept is indicated for the management of patients with moderate to severe chronic plaque psoriasis in adult patients who ... Due to availability of better tolerated and more efficacious molecules for psoriasis, alefacept was withdrawn from use by its ... Alefacept is used to control inflammation in moderate to severe psoriasis with plaque formation, where it interferes with ...
"2020.3.13.psoriasis , Our Dermatology Online journal" (in Polish). Retrieved 2022-03-10. Yap, Jeremy Kean Yi; Pickard, Benjamin ...
Plaques of psoriasis A persons arm covered with plaque psoriasis Psoriasis of the palms Additional types of psoriasis comprise ... Seborrheic-like psoriasis is a common form of psoriasis with clinical aspects of psoriasis and seborrheic dermatitis, and it ... Psoriasis vulgaris (also known as chronic stationary psoriasis or plaque-like psoriasis) is the most common form and affects 85 ... the Psoriasis Association in the United Kingdom, and Psoriasis Australia offer advocacy and education about psoriasis in their ...
Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. Some people also get ... Psoriasis (American Academy of Family Physicians) Also in Spanish * Spotlight on Psoriasis: Preventing Patches of Itchy, Sore ... What Is Psoriasis? (National Institute of Arthritis and Musculoskeletal and Skin Diseases) Also in Spanish ... Psoriasis can be hard to diagnose because it can look like other skin diseases. Your doctor might need to look at a small skin ...
Psoriasis Center of Excellence includes the latest research, journal articles, Medscape TV, cases, quizzes, and peer discussion ...
Psoriasis represents a chronic inflammatory skin condition with a complex pathophysiology and significant genetic background. ... Other characteristic forms comprise erythrodermic psoriasis, guttate psoriasis, palmoplantar psoriasis, inverse psoriasis, and ... Chronic plaque psoriasis represents the main type of psoriasis and is found in approximately 90% of cases. ... What Is Psoriasis?. Play. Although Hippocrates described scaling diseases of the skin under the heading lopoi, the first ...
A unique study with 5,438 Swedish psoriasis patients now reveals that women have a statistically significant lower incidence of ... The fact that men are overrepresented in psoriasis registers and consume more psoriasis care have long led researchers to ... Suffering from Psoriasis? Blame This Trio of Proteins. Nov. 19, 2021 About 7.5 million Americans suffer from psoriasis, an ... Severity of Psoriasis Differs Between Men and Women: A Study of the Clinical Outcome Measure Psoriasis Area and Severity Index ...
Plaque psoriasis (see the image below) is rarely life threatening, but it often is intractable to treatment. ... which manifests most often as plaque psoriasis, is a chronic, relapsing, inflammatory skin disorder with a strong genetic basis ... Plaque psoriasis. Photomicrograph of psoriasis. (1) Hyperkeratosis and parakeratosis, (2) neutrophils in the epidermis, (3) ... encoded search term (Plaque Psoriasis) and Plaque Psoriasis What to Read Next on Medscape ...
Psoriasis can affect the elbows, and it usually appears on both sides of the body. Learn more. ... erythrodermic psoriasis. Although elbow psoriasis can be any type, it is usually plaque psoriasis. This is the most common form ... Elbow psoriasis is most likely to be a form of the condition known as plaque psoriasis. A person will experience raised, ... Elbow psoriasis is a form of psoriasis that is present on one or both elbows. ...
Find out how others living with psoriasis wind down after a long day and how they get ready for bed while managing their ... More in More Than Skin Deep with Psoriasis. *. Doctor Discussion Guide: Talking About Your Progressing Psoriasis ... Living with Psoriasis. Personal stories, and an expert conversation on psoriasis for those living with it. ... We scoured our Living with Psoriasis Facebook community as well as Instagram to find out what other psoriasis patients do ...
Mayo Clinic Minute: Psoriasis of the scalp Oct. 10, 2023, 03:00 p.m. CDT ... Wound care, Patch test, Hives and angioedema, Psoriasis, Chronic hives, Contact dermatitis, Dermatitis, Rosacea, Vascul...itis ... Skin biopsy, Melanoma, Atopic dermatitis, Hidradenitis suppurativa, Acne, Psoriasis, Skin cancer, Dermatitis, Basal cel...l ... Pregnancy, Atopic dermatitis, Klippel-Trenaunay syndrome, Psoriasis, Dermatitis, Vascular malformation, Morphea, Skin p... ...
... have psoriasis, a chronic inflammatory disease that mostly affects the skin and joints but could also affect the na ... psoriasis Psoriasis nail psoriasis treatment nail psoriasis prevention reducing nail psoriasis how to improve nail psoriasis ... "Nail psoriasis may also be a sign of psoriatic arthritis, a type of arthritis that can occur in psoriasis patients. If you ... However, its also possible for patients to experience nail psoriasis without having psoriasis on other parts of their body. ...
Potential therapeutic nutrients and adverse effects of alcohol in psoriasis. ... Additional Keywords : Gluten-Free Diet : CK(11) : AC(2), Nutrition : CK(11) : AC(2), Psoriasis : CK(1) : AC(1), Selenium : CK(3 ... Review: Potential therapeutic nutrients and adverse effects of alcohol in psoriasis. - GreenMedInfo Summary ... Nutritional supplementation may provide a viable treatment alternative in patients with psoriasis. Randomized, controlled ...
BG-12 From Biogen Idec Effective Against Psoriasis - read this article along with other careers information, tips and advice on ... Biogen Idec said that BG-12, a compound licensed from privately held Fumapharm of Switzerland, reduced psoriasis outbreaks by ... BG-12 From Biogen Idec Effective Against Psoriasis. Published: Apr 07, 2005 ...
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... our understanding of psoriasis has improved significantly. This has opened up new treatment options. ... Psoriasis therapy. In recent years and decades, our understanding of psoriasis has improved significantly. This has opened up ... What does our clinic and psoriasis consultation offer you?. Depending on the location, severity and course of the psoriasis, ... Skin care for psoriasis. The success of treatment for this chronic skin disease, which is prone to relapse, depends to a large ...
... learn how NPF is still here to help the psoriasis and psoriatic arthritis community. ... Is it Psoriasis or Eczema?. My Pregnancy with Psoriatic Disease. A Champion for Change. ... Copyright © 1996-2023 National Psoriasis Foundation/USA. Duplication, rebroadcast, republication, or other use of content ... NPF does not endorse any specific treatments or medications for psoriasis and psoriatic arthritis. ...
Scalp psoriasis often causes red, scaly patches on the scalp that may itch or feel sore. These patches can extend beyond the ... Psoriasis on the scalp is a common place where this skin condition can occur Scalp psoriasis is a type of plaque psoriasis. It ... Psoriasis on the scalp is a common place where this skin condition can occur. *Scalp psoriasis is a type of plaque psoriasis. ... Erythrodermic psoriasis - This is a rare form of psoriasis affecting nearly all the skin on the body and causing intense ...
Hier findest Du Menschen, die von der Hautkrankheit Schuppenflechte (Psoriasis), der Gelenkerkrankung Psoriasis arthritis oder ... Informationen im Psoriasis-Netz sollen dich beim Umgang mit deiner Gesundheit unterstützen. Sie sollen und können nicht als ... Krafttraining oder funktionelles Training - was hilft bei Psoriasis arthritis besser? Redaktion posted an article in Magazin, ... Willkommen in der Community für Menschen mit Schuppenflechte und Psoriasis arthritis. Ohne Werbung, ohne Tracking, aber mit ...
Therapies for psoriasis. Authoritative facts from DermNet New Zealand. ... including chronic plaque psoriasis, guttate psoriasis, flexural psoriasis, palmoplantar psoriasis, and nail psoriasis. ... Topical steroids are safe and relatively easy to use for plaque psoriasis, scalp psoriasis, flexural psoriasis, sebopsoriasis, ... Bath treatment of psoriasis, Probiotics for psoriasis, Topical treatments for psoriasis - emollients, keratolytics, steroids, ...
Psoriasis has been recently established to be a systemic disease centered on inflammation and involvement of cytokines of the ... On application to psoriasis management and prognosis, the goal is to decrease the risk for cardiovascular disease and decrease ... This paper proposes the idea of the potential use of oral vitamin D to treat psoriasis and metabolic syndrome concurrently. We ... There is an increased prevalence of metabolic syndrome in patients with psoriasis. Metabolic syndrome also involves a ...
Dermatologists are advised to discuss alcohol use with their patients who have psoriasis and to familiarize themselves with ... AAD > Psoriasis Psoriasis: A Red Flag for Screening for Alcohol Misuse. - Screening tools, quick interventions, familiarity ... Source Reference: Kearney N, Kirby B. "Alcohol and psoriasis for the dermatologist: Know, screen, intervene" Am J Clin Dermatol ... It is well-established that people with psoriasis tend to consume more alcohol than the general population. Alcohol consumption ...
While it has been known for some time that psoriasis patients are at increased risk of developing cardiovascular disease and ... Psoriasis Severity Escalates Risk for Aortic Aneurysm. August 17, 2016. Amy Jacob ... However, to understand the risk for aortic aneurysm among patients with psoriasis, Chu and his team used the Taiwan National ... While it has been known for some time that psoriasis patients are at increased risk of developing cardiovascular disease and ...
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"We purposely went slowly with the first patients because this has never been attempted before-treating generalized psoriasis ... then as needed thereafter to maintain a Psoriasis Area and Severity Index (PASI) 75 response. For the last four weeks, patients ... impressive results in patients with severe generalized psoriasis, as reported by Dermatology Times. ... impressive results in patients with severe generalized psoriasis. ... Excimer laser combination boosts laser therapy in psoriasis ...
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About Psoriasis. Psoriasis is a common, chronic and life-altering skin disease that affects approximately one million Canadians ... with 90% of those affected suffering from plaque psoriasis.4. Plaque psoriasis disease is characterized by red elevated patches ... Psoriasis can impact nearly every aspect of an individuals life including their ability to work and maintain social and ... It is very good news for Quebecers with plaque psoriasis to have a new topical treatment option available to them through the ...
Detailed information about psoriasis, its types, symptoms, causes, treatments and skin care. ... Facts About Psoriasis. * Psoriasis is a chronic disease. It goes into remission from time to time and flares up sometimes. ... Psoriasis is not a contagious condition. * Psoriasis is not life threatening at most of the times, but it causes lot of ... Steroids are the common treatment for psoriasis, but they cannot be used for a long time. ...
"From spending my childhood in my mothers salon to my father applying oil on my scalp to treat my psoriasis- these moments have ... Beyoncé opens up on deeply personal journey with her hair as she discusses psoriasis treatment. Beyoncé. Picture: Mario ...
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How much do you know about the five primary types of psoriasis? Test your knowledge with this short quiz. ... Psoriasis is generally divided into five main types: plaque, inverse, guttate, erythrodermic, and pustular psoriasis. Knowledge ... Most Patients With Psoriasis Not Engaged in Highly Shared Decision-Making * Phenotype-Targeted Treatment Sought for Psoriatic ... Concepts to Practice: The Evolving Landscape in Topical Therapies for Plaque Psoriasis 0.75 CME / CE / ABIM MOC Credits ...
  • Guttate psoriasis has drop-shaped lesions. (wikipedia.org)
  • Guttate psoriasis is an inflammatory condition characterized by numerous small, scaly, red or pink, droplet-like lesions (papules). (wikipedia.org)
  • Guttate psoriasis is often triggered by a streptococcal infection (oropharyngeal or perianal) and typically occurs 1-3 weeks post-infection. (wikipedia.org)
  • Guttate psoriasis is most commonly seen in children and young adults and diagnosis is typically made based on history and clinical exam findings. (wikipedia.org)
  • Other characteristic forms comprise erythrodermic psoriasis, guttate psoriasis, palmoplantar psoriasis, inverse psoriasis, and both localized and generalized pustular psoriasis. (news-medical.net)
  • Guttate psoriasis - This causes small drop shaped sores on the chest, arms, legs and scalp although this type may disappear completely after a few weeks. (amoils.com)
  • Guttate psoriasis sometimes appears after a streptococcal throat infection and may go on to become plaque psoriasis. (amoils.com)
  • infections (There's a documented link between strep throat and guttate psoriasis . (greatist.com)
  • There are a number of types of psoriasis, including chronic plaque psoriasis , guttate psoriasis , flexural psoriasis , palmoplantar psoriasis , and nail psoriasis . (dermnetnz.org)
  • Heat, trauma, and infection are thought to play a role in the development of this atypical form of psoriasis. (wikipedia.org)
  • Elbow psoriasis is a form of psoriasis that is present on one or both elbows. (medicalnewstoday.com)
  • According to dermatologists from the American Academy of Dermatology, most people who have plaque psoriasis - the most common form of psoriasis - also develop nail psoriasis at some point. (newswise.com)
  • Generalised pustular psoriasis - This is a rare and more serious form of psoriasis usually requiring emergency treatment and causing pustules to develop very quickly on a wide area of skin. (amoils.com)
  • Erythrodermic psoriasis - This is a rare form of psoriasis affecting nearly all the skin on the body and causing intense itching or burning. (amoils.com)
  • More details about each form of psoriasis treatment are found on individual topic pages. (dermnetnz.org)
  • Plaques of psoriasis A person's arm covered with plaque psoriasis Psoriasis of the palms Additional types of psoriasis comprise about 10% of cases. (wikipedia.org)
  • There are several different types of psoriasis. (medicalnewstoday.com)
  • What are the other types of psoriasis? (amoils.com)
  • Fast Five Quiz: Can You Recognize Different Types of Psoriasis? (medscape.com)
  • How much do you know about the five primary types of psoriasis? (medscape.com)
  • Psoriatic arthritis affects up to 30% of individuals with psoriasis. (wikipedia.org)
  • Some people who have psoriasis also get a form of arthritis called psoriatic arthritis . (medlineplus.gov)
  • Incidence and clinical predictors of psoriatic arthritis in patients with psoriasis: a population-based study. (medscape.com)
  • Nail psoriasis may also be a sign of psoriatic arthritis, a type of arthritis that can occur in psoriasis patients. (newswise.com)
  • NPF does not endorse any specific treatments or medications for psoriasis and psoriatic arthritis. (psoriasis.org)
  • Health conditions associated with psoriasis include psoriatic arthritis , sleep disturbance, and depression. (dermnetnz.org)
  • The Greek version is published by Panhellenic Society of Patients with Psoriasis and Psoriatic Arthritis EPIDERMIA, Greece. (who.int)
  • Plaque psoriasis, also known as psoriasis vulgaris, makes up about 90% of cases. (wikipedia.org)
  • Psoriasis vulgaris (also known as chronic stationary psoriasis or plaque-like psoriasis) is the most common form and affects 85-90% of people with psoriasis. (wikipedia.org)
  • Plaque psoriasis typically appears as raised areas of inflamed skin covered with silvery-white, scaly skin. (wikipedia.org)
  • Chronic plaque psoriasis represents the main type of psoriasis and is found in approximately 90% of cases. (news-medical.net)
  • Lowes R. FDA approves apremilast (Otezla) for plaque psoriasis. (medscape.com)
  • Calzavara-Pinton PG, Sala R, Arisi M, Rossi MT, Venturini M, Ortel B. Synergism between narrowband ultraviolet B phototherapy and etanercept for the treatment of plaque-type psoriasis. (medscape.com)
  • A randomized study to evaluate the efficacy and safety of adding topical therapy to etanercept in patients with moderate to severe plaque psoriasis. (medscape.com)
  • Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: efficacy and safety results from the 52-week, randomized, double-blinded, placebo-controlled phase 3 POETYK PSO-1 trial. (medscape.com)
  • Secukinumab in plaque psoriasis--results of two phase 3 trials. (medscape.com)
  • Although elbow psoriasis can be any type, it is usually plaque psoriasis. (medicalnewstoday.com)
  • A 2021 study reports that visible nail changes are common in those with plaque psoriasis. (medicalnewstoday.com)
  • Elbow psoriasis is most likely to be a form of the condition known as plaque psoriasis. (medicalnewstoday.com)
  • Drug frequently used in Germany for the systemic treatment of plaque psoriasis. (usz.ch)
  • Scalp psoriasis is a type of plaque psoriasis. (amoils.com)
  • So when a psoriasis flare spreads, it's not because you accidentally touched your arm to the plaque on your leg. (greatist.com)
  • Plaque psoriasis is raised, roughened, and covered with white or silver scale with underlying erythema. (medscape.com)
  • Pustular psoriasis presents as small, noninfectious, pus-filled blisters. (wikipedia.org)
  • Pustular psoriasis appears as raised bumps filled with noninfectious pus (pustules). (wikipedia.org)
  • Pustular psoriasis can either be localized or more widespread throughout the body. (wikipedia.org)
  • Pustular psoriasis - This is a more rare type, causing pus-filled blisters to appear on the skin and affecting different parts of the body. (amoils.com)
  • A comparative non randomized study of narrow-band (NB) (312 +/- 2 nm) UVB phototherapy versus sequential therapy with oral administration of low-dose Cyclosporin A and NB-UVB phototherapy in patients with severe psoriasis vulgaris. (medscape.com)
  • Background: Psoriasis Vulgaris is the commonest encountered type of psoriasis and it accounts for approximately 90% of cases. (bartleby.com)
  • c) Marital status and Employment status: In Mauritius 66% who had psoriasis vulgaris was married and in Dalian 56% was married. (bartleby.com)
  • Inverse psoriasis forms red patches in skin folds. (wikipedia.org)
  • Inverse psoriasis (also known as flexural psoriasis) appears as smooth, inflamed patches of skin. (wikipedia.org)
  • Inverse (flexural) psoriasis - This affects the folds or creases in the skin, for example the armpits, groin, between the buttocks or under the breasts, causing large and smooth patches of skin. (amoils.com)
  • Inverse psoriasis. (greatist.com)
  • This type of psoriasis works symmetrically, so the condition will likely affect both elbows. (medicalnewstoday.com)
  • PSA: This type of psoriasis is super rare, but it can be life threatening. (greatist.com)
  • The diagnosis of psoriasis is clinical, and the type of psoriasis present affects the physical examination findings. (medscape.com)
  • Many patients who have difficult-to-treat psoriasis on their palms and soles (palmoplantar psoriasis) see clearing when they use coal tar along with a corticosteroid that they apply to their psoriasis. (aad.org)
  • Erythrodermic psoriasis occurs when the rash becomes very widespread, and can develop from any of the other types. (wikipedia.org)
  • If you're experiencing symptoms of erythrodermic psoriasis, get to the emergency room! (greatist.com)
  • When you have moderate to severe psoriasis , you may be up to 50% more likely to get heart disease than someone who doesn't have the condition. (webmd.com)
  • Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials. (medscape.com)
  • Moderate-to-severe psoriasis is associated with a dose-dependent risk for cardiovascular and metabolic morbidity. (sciencedaily.com)
  • Methods: A network meta-analysis (NMA) was conducted to indirectly compare the efficacy of six biologics in achieving complete resolution of NP at week 24‒26 in patients with moderate-to-severe psoriasis and concomitant NP. (lu.se)
  • 17%). Conclusion: In patients with moderate-to-severe psoriasis and concomitant NP, ixekizumab has the greatest likelihood among approved biologics of achieving complete resolution of NP at week 24‒26. (lu.se)
  • There is no known cure for psoriasis, but various treatments can help control the symptoms. (wikipedia.org)
  • There are various treatments a person can try for elbow psoriasis. (medicalnewstoday.com)
  • Individuals may also wish to seek a doctor's advice when experiencing a psoriasis flare-up, particularly if current treatments do not help manage symptoms. (medicalnewstoday.com)
  • You'll find many psoriasis treatments that contain coal tar. (aad.org)
  • A payer-perspective cost model was developed to estimate and compare the direct expenditures associated with a 30-year course of various treatments for severe psoriasis. (nih.gov)
  • If you're having trouble managing your psoriasis symptoms, talk with your doctor about possible treatments. (greatist.com)
  • Doctors may also prescribe topical or oral treatments for your psoriasis to stop your skin cells from reproducing so quickly. (sharecare.com)
  • This review was conducted via PubMed , aiming to search for studies involving psoriasis linked with metabolic disorders or with nutritional treatments . (bvsalud.org)
  • And although psoriasis symptoms are most visible on your skin, inflammation affects other parts of the body, too, including your heart . (webmd.com)
  • According to recent estimates, psoriasis affects 2-3% of the world's population, which is approximately 125 million people. (news-medical.net)
  • The fact that men are overrepresented in psoriasis registers and consume more psoriasis care have long led researchers to believe that the common skin disease disproportionately affects men. (sciencedaily.com)
  • According to research , psoriasis typically affects both sides of the body in a symmetrical pattern. (medicalnewstoday.com)
  • Newswise - ROSEMONT, Ill. (June 11, 2020) - Approximately 7.5 million people in the U.S. [1] have psoriasis, a chronic inflammatory disease that mostly affects the skin and joints but could also affect the nails. (newswise.com)
  • Psoriasis is a chronic (long-lasting) skin disease of scaling and inflammation that affects more than three percent of the U. (medlineplus.gov)
  • Learn more about psoriasis triggers. (medicalnewstoday.com)
  • Both psoriasis and eczema may have similar triggers, too, like stress, and neither of the conditions is contagious. (sharecare.com)
  • Psoriasis triggers may include stress, medications such as beta-blockers and lithium, illnesses and dry, cold air. (sharecare.com)
  • Psoriasis can affect any part of the body, including the elbows. (medicalnewstoday.com)
  • People should contact a doctor as soon as they experience any psoriasis symptoms on their elbows. (medicalnewstoday.com)
  • In the majority of psoriasis patients (80 percent), the infestation is so limited, e.g. on the scalp, elbows and knees, that local treatment is sufficient for successful therapy. (usz.ch)
  • This is why dermatologists say it's important for psoriasis patients to check their nails - both their fingernails and toenails - for signs of nail psoriasis, which can include nail dents, lifting, discoloration, thickening and crumbling. (newswise.com)
  • However, it's also possible for patients to experience nail psoriasis without having psoriasis on other parts of their body. (newswise.com)
  • There are many treatment options available for nail psoriasis, including topical and oral medications, corticosteroid injections, and biologics," says board-certified dermatologist Richard K. Scher, MD, FAAD. (newswise.com)
  • However, nail psoriasis can be challenging to treat. (newswise.com)
  • It can also help prevent buildup under the nails - a common issue associated with nail psoriasis. (newswise.com)
  • Nail psoriasis can be stubborn, however, the combination of treatment and the recommended at-home care can help clear nail psoriasis and reduce pain," says Dr. Scher. (newswise.com)
  • These tips are demonstrated in " How to Improve Nail Psoriasis ," a video posted to the AAD website and YouTube channel . (newswise.com)
  • Nail psoriasis - This causes the nails to develop tiny dents or pits, becoming discolored or growing abnormally. (amoils.com)
  • Background: Nail psoriasis (NP) is common and of high importance in patients with psoriasis. (lu.se)
  • Complete resolution of NP was defined as a score of zero on the Nail Psoriasis Severity Index (NAPSI), modified NAPSI (mNAPSI) or Physician's Global Assessment of Fingernails. (lu.se)
  • One patient also developed thumb nail psoriasis and paronychia. (cdc.gov)
  • Some studies suggest that people who treat moderate or severe psoriasis have fewer heart attacks , strokes, and heart-related deaths. (webmd.com)
  • A unique study with 5,438 Swedish psoriasis patients now reveals that women have a statistically significant lower incidence of severe psoriasis compared to men. (sciencedaily.com)
  • Our results tell us that the well-established gender differences in the utilization of psoriasis care can at least partially be explained by a higher prevalence of more severe disease in men," says Marcus Schmitt-Egenolf, who is researcher at the Department of Public Health and Clinical Medicine at Umeå University and senior author of the study. (sciencedaily.com)
  • The study of gender differences in severe psoriasis cases was based on the Swedish quality register for systemic treatment of psoriasis, PsoReg, which contains detailed disease measurement data on all patients measured with the standard method Psoriasis Area Severity Index (PASI). (sciencedaily.com)
  • The findings of more severe psoriasis in men were consistent across all ages and in all areas of the body except for the head. (sciencedaily.com)
  • These findings should motivate a gender perspective in the management of severe psoriasis and its comorbidities, such as cardiovascular and metabolic disease," says Marcus Schmitt-Egenolf. (sciencedaily.com)
  • Instead, the researchers argue, the finding that women have less severe psoriasis can explain the well-known male dominance in systemic treatment of psoriasis. (sciencedaily.com)
  • For over 70 years, psoriasis researchers have speculated that women have less severe psoriasis compared to men. (sciencedaily.com)
  • In contrast to the situation in severe psoriasis, most autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis (MS) and rheumatoid arthritis (RA), are more prevalent in women than in men. (sciencedaily.com)
  • The cost of treating severe psoriasis has risen dramatically, and treatment options vary widely in terms of cost and efficacy. (nih.gov)
  • Phototherapy is of great importance in the treatment of moderate and severe psoriasis. (usz.ch)
  • Internal or systemic therapies are also used for extensive or severe forms of psoriasis - especially if the joints are also affected. (usz.ch)
  • It also has an excellent effect on psoriasis, especially on severe and highly inflammatory forms. (usz.ch)
  • Adverse events from systemic therapies for psoriasis are common in clinical practice. (medscape.com)
  • Lé AM, Torres T. New Topical Therapies for Psoriasis. (medscape.com)
  • Dual therapies of ultraviolet B phototherapy and fish oil, retinoids and thiazolidinediones, and cyclosporine and a low-calorie diet were effective in the treatment of psoriasis in randomized, controlled trials. (greenmedinfo.com)
  • The aim of this review was to identify the relationship between psoriasis , metabolic diseases , and dietetic therapies . (bvsalud.org)
  • Psoriasis represents a chronic inflammatory skin condition with a complex pathophysiology and significant genetic background. (news-medical.net)
  • Mar. 25, 2024 Scientists have discovered a gene mutation is responsible for causing psoriasis -- a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. (sciencedaily.com)
  • Psoriasis is a complex, chronic, multifactorial, inflammatory disease that involves hyperproliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate (see the image below). (medscape.com)
  • Psoriasis is an inflammatory disease that manifests most commonly as well-circumscribed, erythematous papules and plaques covered with silvery scales. (msdmanuals.com)
  • Psoriasis patches and plaques tend to trigger the growth of new blood vessels, a process called angiogenesis. (webmd.com)
  • Psoriasis is characterized by well-circumscribed, sharply demarcated erythematous papules and plaques. (news-medical.net)
  • These are strong formulas that can reduce inflammation and control the psoriasis plaques. (medicalnewstoday.com)
  • Psoriasis is a common, chronic , immune-mediated skin disease with characteristic red, scaly plaques caused by the excessive proliferation of skin cells. (dermnetnz.org)
  • Psoriasis varies in severity from small localized patches to complete body coverage. (wikipedia.org)
  • Our study is the first to investigate sex differences in psoriasis severity using the golden standard of severity measurement, the PASI score. (sciencedaily.com)
  • The maintaining of a proper body weight together with physical activity and good nutritional choices are associated with an improvement in psoriasis severity. (bvsalud.org)
  • Scalp Psoriasis vs. Seborrheic Dermatitis: What's the Difference? (medlineplus.gov)
  • Dermatologists also include coal tar in a treatment plan for patients who have scalp psoriasis. (aad.org)
  • Coal tar can clear scalp psoriasis and increase remissions on the scalp. (aad.org)
  • Coal tar can be an effective treatment for scalp psoriasis and is found in psoriasis shampoos. (aad.org)
  • When using a coal tar shampoo to treat scalp psoriasis, make sure that the shampoo gets on your scalp. (aad.org)
  • Scalp psoriasis often causes red, scaly patches on the scalp that may itch or feel sore. (amoils.com)
  • Smoking can worsen psoriasis symptoms. (webmd.com)
  • Injuring your skin increases your risk of infection, which could worsen your psoriasis. (newswise.com)
  • Like many autoimmune diseases , psoriasis puts your body's immune system into overdrive. (webmd.com)
  • Here's the scoop: Psoriasis is propelled by your immune system , which is why most docs and researchers file it under " autoimmune diseases . (greatist.com)
  • Psoriasis: current perspectives with an emphasis on treatment. (medscape.com)
  • Goiriz R, Dauden E, Perez-Gala S, Guhl G, Garcia-Diez A. Flare and change of psoriasis morphology during the course of treatment with tumour necrosis factor blockers. (medscape.com)
  • The treatment of psoriasis usually depends on how much skin is affected, how bad the disease is (e.g., having many or painful skin patches), or the location (especially the face). (amcp.org)
  • Nutritional supplementation may provide a viable treatment alternative in patients with psoriasis. (greenmedinfo.com)
  • This contribution also reviews the potential negative effect of alcohol and the potential positive effects of vitamin B(12), selenium, retinoic acid metabolism-blocking agents, and a gluten-free diet in the treatment of psoriasis. (greenmedinfo.com)
  • So finding a good psoriasis treatment that works for you is pretty important. (hypnosisdownloads.com)
  • A pilot study of hypnosis in the treatment of patients with psoriasis. (hypnosisdownloads.com)
  • Psoriasis Treatment has been purchased by 437 customers . (hypnosisdownloads.com)
  • However, we know that not all products work equally well for everybody, so if you find the Psoriasis Treatment download doesn't do what you wanted, simply let us know and we will refund you in full, no questions asked (one order per customer). (hypnosisdownloads.com)
  • UV-A waves can also be highly effective in the treatment of psoriasis. (usz.ch)
  • It is effective in the treatment of both skin and joint psoriasis. (usz.ch)
  • There's currently no cure for psoriasis (ugh), but there are heaps of at-home and medical treatment options. (greatist.com)
  • These similarities can make psoriasis and eczema tough for doctors to diagnose, but being aware of some of the differences can help you get the proper diagnosis and treatment for your particular skin woes. (sharecare.com)
  • 4. Treatment differs for psoriasis and eczema. (sharecare.com)
  • Treatment choice in psoriasis depends on a number of factors. (dermnetnz.org)
  • One avenue of current research is looking at the skin and gut microbiome (the bacteria living on and in the human body) and whether the alteration of this microbiome may be effective in the treatment of psoriasis [4,5]. (dermnetnz.org)
  • Psoriasis in Skin of Color: Insights into the Epidemiology, Clinical Presentation, Genetics, Quality-of-Life Impact, and Treatment of Psoriasis in Non-White Racial/Ethnic Groups. (msdmanuals.com)
  • Sterry W, Strober BE, Menter A. Obesity in psoriasis: the metabolic, clinical and therapeutic implications. (medscape.com)
  • Due to the association between psoriasis and metabolic syndrome , weight loss, smoking cessation , moderation of alcohol intake , and blood pressure control may also lead to improvements in skin disease [1,2]. (dermnetnz.org)
  • Metabolic Disorders and Psoriasis: Exploring the Role of Nutritional Interventions. (bvsalud.org)
  • Psoriasis is a chronic autoimmune disease with a close relationship with metabolic diseases such as obesity , diabetes, and dyslipidemia . (bvsalud.org)
  • Having psoriasis and dealing with flare-ups at work can be stressful. (healthline.com)
  • Instead, psoriasis flare-ups spread on your body because of an internal immune response. (greatist.com)
  • Most psoriasis flare-ups start as a small itchy patch that spreads pretty quickly. (greatist.com)
  • Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. (medlineplus.gov)
  • Itchy, irritated skin and blotchy, red patches are just two symptoms that psoriasis and eczema share that can make it hard to tell the common skin conditions apart. (sharecare.com)
  • Where possible, minimise factors that aggravate or trigger psoriasis, such as stress, streptococcal infections , and certain medications ( lithium , beta-blockers, and antimalarial drugs ). (dermnetnz.org)
  • Fingernails and toenails are affected in most people with psoriasis at some point in time. (wikipedia.org)
  • Research shows that people with psoriasis have more heart disease risk factors than people who don't. (webmd.com)
  • People with psoriasis tend to have more of these microparticles than people without the condition. (webmd.com)
  • Although they don't have clear answers about any of these factors, what they do know is that on average, people with psoriasis have a shorter life expectancy by 5 years. (webmd.com)
  • The symptoms of psoriasis disappeared at present and the level of anxiety of both participants decrease. (bvsalud.org)
  • Hier findest Du Menschen, die von der Hautkrankheit Schuppenflechte (Psoriasis), der Gelenkerkrankung Psoriasis arthritis oder von beidem betroffen sind. (psoriasis-netz.de)
  • Eine neue Studie zeigt, dass Menschen mit Psoriasis arthritis regelmäßig viele Medikamente nehmen. (psoriasis-netz.de)
  • Gesucht werden nun Patienten mit Psoriasis arthritis, Systemischem Lupus erythematodes und Rheumatoider Arthritis. (psoriasis-netz.de)
  • Willkommen in der Community für Menschen mit Schuppenflechte und Psoriasis arthritis. (psoriasis-netz.de)
  • Still, the term 'psoriasis' was first used by a well-known Greek physician Galen, who derived it from the Greek word 'psora' which means itch. (news-medical.net)
  • To date, studies fail to show an increased risk of cancer in people who use coal tar to treat psoriasis or atopic dermatitis (eczema). (aad.org)
  • Nov. 19, 2021 About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. (sciencedaily.com)
  • Psoriasis causes thick red or white patches that can also appear silvery and scaly. (sharecare.com)
  • Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. (wikipedia.org)
  • Psoriasis can be hard to diagnose because it can look like other skin diseases. (medlineplus.gov)
  • Although Hippocrates described scaling diseases of the skin under the heading 'lopoi,' the first clinical description of psoriasis is attributed to Aurelius Celsus who mentioned this disease in his work De re medica . (news-medical.net)
  • Psoriasis is a common autoimmune skin disease affecting about three percent of the Swedish population. (sciencedaily.com)
  • Psoriasis is a skin condition affecting approximately 3% of the population of the United States. (medicalnewstoday.com)
  • When you have psoriasis, your nightly routine can impact your symptom management and how your skin will look and feel the next morning. (healthline.com)
  • Psoriasis is a chronic autoimmune skin disease that speeds up the growth cycle of skin cells. (amcp.org)
  • Psoriasis often has a typical appearance that a primary care doctor can recognize, but it can be confused with other skin diseases (like eczema), so a dermatologist (skin doctor) is often the best doctor to diagnose it. (amcp.org)
  • Any time you irritate your skin or nails, psoriasis can flare. (newswise.com)
  • Engineered cells detect early biomarkers of a psoriasis flare-up in mice and release compounds to soothe or prevent the skin reaction. (the-scientist.com)
  • Psoriasis is an unpleasant skin condition which can make your life really miserable. (hypnosisdownloads.com)
  • Psoriasis , however, is a genetic autoimmune condition where skin cells grow too quickly, resulting in thick and uncomfortable raised patches of skin. (sharecare.com)
  • See Psoriasis: Manifestations, Management Options, and Mimics , a Critical Images slideshow, to help recognize the major psoriasis subtypes and distinguish them from other skin lesions. (medscape.com)
  • A complex interplay between genetic factors and immunology culminates in the specific clinical and histological features of psoriasis. (news-medical.net)
  • In synergy with standard therapy , the adoption of an appropriate diet can be recommended to improve the clinical expression of psoriasis and reduce the incidence of comorbidities. (bvsalud.org)
  • Psoriasis may trigger inflammation in body fat (adipose tissue). (webmd.com)
  • Psoriasis is hyperproliferation of epidermal keratinocytes combined with inflammation of the epidermis and dermis. (msdmanuals.com)
  • Prescribing coal tar: Dermatologists have been prescribing coal tar for more than 100 years to treat psoriasis. (aad.org)
  • Dermatologists have been prescribing coal tar for more than 100 years to treat psoriasis, and it is considered safe for long-term use. (aad.org)
  • In California, you'll find cancer warnings on some coal tar products you can use to treat psoriasis. (aad.org)
  • You'll find coal tar in many different products used to treat psoriasis. (aad.org)
  • Some people believe dairy, alcohol, sugar and red meat may also trigger psoriasis flares. (sharecare.com)
  • Napkin psoriasis is often misdiagnosed as napkin dermatitis (diaper rash). (wikipedia.org)
  • It's best to get help from a doctor or dermatologist who specializes in psoriasis. (greatist.com)
  • Despite these staggering numbers, the incidence rate of psoriasis remains low, with a rate of roughly 92.3 new cases per 100,000 people per year worldwide. (news-medical.net)

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