AAA proteins

Proteins@home

PIN proteins

FOX proteins

SIR proteins

FANC proteins

Notch proteins

IFIT proteins

Proteins (journal)

Transformer proteins

SIBLING proteins

Duffy binding proteins

Complex lasso proteins

Iron-binding proteins

Bacteriophage scaffolding proteins

Toroid repeat proteins

Thyroxine-binding proteins

Tight junction proteins

Polycomb-group proteins

Tardigrade specific proteins

Major urinary proteins

Cyanobacterial clock proteins

International Therapeutic Proteins

Intrinsically disordered proteins

List of proteins

Methuselah-like proteins

Calmodulin-binding proteins

Proteins in wine

Angiopoietin-like proteins

Vesiculovirus matrix proteins

Animal proteins4

• Like other animal proteins , casein is a complete protein source. (healthline.com)
• Like other animal proteins, it contains all the essential amino acids that your own body is unable to produce naturally. (healthline.com)
• Traditionally, animal proteins have been the main source of protein in the human diet. (ift.org)
• 1.5 kilogrammes of vegetable proteins, 0.5 kilogramme of animal proteins. (nzdl.org)

Bioactive compounds2

• It also contains various unique proteins and bioactive compounds, some of which have health benefits ( 2 , 3 ). (healthline.com)
• HPP is the most explored alternative approach in the recovery of proteins and bioactive compounds. (ift.org)

Molecules6

• o Methods to elucidate the organization of lipid and detergent molecules within protein crystalline arrays (e.g., neutron diffraction). (nih.gov)
• Van der waal's force  Van der Waals force is interaction of proteins with other molecules or with surfaces when they come close to each other. (slideshare.net)
• Denaturation does not involve identical changes in protein molecules. (britannica.com)
• Thus, imaging the surfaces of these proteins in detail can help scientists identify molecules that will bind to them and aid in turning the protein activity off. (cancer.gov)
• Mass spectrometers first convert protein molecules into gas-phase ions using an ion source. (sigmaaldrich.com)
• MALDI is an ionization method that uses a laser energy-absorbing matrix to generate ions with minimal fragmentation of protein molecules. (sigmaaldrich.com)

Types of proteins2

• Milk contains two types of proteins - casein and whey. (healthline.com)
• These types of proteins are generally found in plasma membranes, cytosol and in cellular organelles. (slideshare.net)

Soluble protein2

• Dr. Tjandra is studying how Bax transforms from a soluble protein in the cytoplasm to a membrane-associated protein that irreversibly promotes cell death. (nih.gov)
• However, during this same decade the rate of soluble protein structure solution has accelerated greatly and there remains a gap between the understanding of membrane proteins and their soluble protein counterparts. (nih.gov)

Interactions8

• The goal is to understand how protein-protein interactions involving CP can manage a relatively fast actin polymerization response to cellular stimuli. (nih.gov)
• PROTEIN - PROTEIN INTERACTIONS  Protein-protein interactions (PPIs) are the physical contacts between two or more proteins to perform complex biological functions. (slideshare.net)
• Yeast two hybrid system  It detects the interactions between the query protein of interest and the known protein in yeast system. (slideshare.net)
• Interactions of proteins outside nucleus are difficult to be studied. (slideshare.net)
• Studies have shown that the allosteric signal is transmitted a through a network of residue-residue interactions connecting distal sites on a protein. (nih.gov)
• In my Mildred Cohn Award Lecture at the 2019 ASBMB meeting, I illustrated the power of such multidisciplinary work by highlighting the successful integration of data and multiple views afforded by NMR spectroscopy, cryo-electron microscopy, cryo-electron tomography, X-ray crystallography, computation, and functional assays made possible through collaborative efforts by members of the Pittsburgh Center for HIV Protein Interactions. (jbc.org)
• Mass spectrometry is used to quantitatively identify and characterize proteins based on their structure, post-translational modifications, and interactions. (sigmaaldrich.com)
• Protein interactions are determined by affinity co-purification of a specific target protein with any interacting proteins or studied more globally using size exclusion or ion exchange chromatography prior to analysis by mass spectrometry. (sigmaaldrich.com)

Structures13

• This PA solicits applications to develop research and methods to enhance the rate of membrane protein structure determination and to determine specific membrane protein structures. (nih.gov)
• Projects that will lead in the near term to determining the structures of biologically important membrane proteins are also encouraged. (nih.gov)
• NCBI's Protein resources include protein sequences and structures and related comparison and visualization tools, as well as databases and tools to predict and analyze functional domains. (nih.gov)
• Considerable research is ongoing in the area of membrane protein structure and function, yet relatively few investigators have applied the techniques of x-ray crystallography, electron diffraction, or nuclear magnetic resonance (NMR) spectroscopy to study directly the structures of their proteins. (nih.gov)
• This progress clearly demonstrates that obtaining membrane protein structures is feasible. (nih.gov)
• Nonetheless, there remains a need for a separate program initiative that focuses primarily on membrane proteins and the development of methods for solving their structures. (nih.gov)
• An increase in the number of known membrane protein structures will contribute to an enhanced understanding of many basic phenomena underlying cellular functions essential to human health. (nih.gov)
• Despite the importance of membrane proteins, the knowledge of their high resolution structures and mechanisms of action has lagged far behind the knowledge of these properties of proteins in general. (nih.gov)
• Because the tissues were fragments by probing with a panel of BSE (C-BSE) and 2 so-called severely autolyzed, target structures of antibodies in the Western blot that atypical types of BSE with higher for the diagnosis of BSE could not bind to different regions of the prion or lower molecular masses of PrPres be identifi ed, and histopathologic and protein (online Technical Appendix). (cdc.gov)
• The structures of both proteins suggest that they lay in the hair cell's membrane, as would be expected for parts of the molecular channel, and in the absence of the proteins, the MET channel doesn't function normally. (nih.gov)
• This is a terrific source for protein and small biomolecule structures (lipids, carbohydrates). (merlot.org)
• Cryo-EM imaging enables analysis of structures of target proteins bound to drug candidates without first needing a step to coax the proteins to form ordered arrays. (cancer.gov)
• The fact that we can obtain structures of small cancer target proteins bound to drug candidates without needing to form 3D crystals could revolutionize and accelerate the drug discovery process. (cancer.gov)

Researchers18

• Researchers linked these brain benefits to a protein called GPLD1. (nih.gov)
• Researchers have now found evidence that the activity of LRRK2 protein might be affected in many more patients with Parkinson's disease, even when the LRRK2 gene itself is not mutated. (nih.gov)
• These researchers found a quicker and larger spike from whey protein due to its rapid absorption rate. (healthline.com)
• In another study, researchers gave participants either whey or casein protein and then measured their digestion rate by analyzing circulating levels of the amino acid, leucine, over a seven-hour period. (healthline.com)
• The overall philosophy of the Protein Expression Facility is to provide researchers with knowledge and expertise, tools for their work, as well as guidance and mentoring in an all-inclusive and participatory manner. (nih.gov)
• To further investigate the location of TMC 1 and TMC2 in the MET channel, the researchers tagged mouse hair cells with with fluorescent proteins and observed the proteins using high-resolution confocal microscopy. (nih.gov)
• GAINESVILLE, Fla. -- University of Florida Health researchers have made a new discovery about Huntington's disease, showing that the gene that causes the fatal disorder makes an unexpected "cocktail" of mutant proteins that accumulate in the brain. (eurekalert.org)
• Along with a protein already implicated in Huntington's disease, the researchers found four proteins that also contribute to the disease pathology. (eurekalert.org)
• However, researchers found that this DNA repeat mutation can undergo a process known as repeat associated non-ATG (RAN) translation, producing four additional damaging repeat proteins that accumulate in the brain. (eurekalert.org)
• This was a surprise to the researchers because these RAN proteins are made without a signal in the genetic code that was previously thought to be required for protein production. (eurekalert.org)
• In addition to finding that the RAN proteins accumulate in the striatum, a specific brain region predominantly affected in Huntington disease, researchers also found them in the frontal cortex, cerebellum and white matter regions of the brain. (eurekalert.org)
• In the cerebellum -- a part of the brain at the back of the skull that controls movement and motor coordination -- the discovery of RAN proteins suggests that they may be responsible for some of the typical uncontrolled movements observed in Huntington disease patients, researchers said. (eurekalert.org)
• On the basis of their findings, the researchers believe there is a possibility that RAN proteins contribute to eight other similar neurodegenerative disorders, including spinobulbar muscular atrophy and several types of spinocerebellar ataxia, which are also caused by an abnormal increase in the number of CAG repeats. (eurekalert.org)
• In addition to the possibility of new therapies, detecting these proteins may be useful for predicting the disease's onset, its progression and treatment responses, researchers said. (eurekalert.org)
• These proteins can even facilitate the generation of new heart cells for patients who need heart surgery, say researchers at the Indian Institute of Technology Guwahati. (nature.com)
• The researchers then isolated and purified the proteins, and studied their efficiency in permeating specific human cells. (nature.com)
• The techniques to produce the proteins are simple, cost-effective and highly reproducible, the researchers note. (nature.com)
• Two of the small proteins the researchers imaged in this new study, isocitrate dehydrogenase (IDH1) and lactate dehydrogenase (LDH), are active targets for cancer drug development. (cancer.gov)

Oats4

• Easy protein ball recipe using chocolate protein powder, natural peanut butter, oats, and seeds. (allrecipes.com)
• In a large bowl, mix together the oats, cocoa powder, and vegan protein powder. (peta.org)
• Made with plant-based protein powder, they're vegan, and they can also be made gluten-free if you use gluten-free oats. (popsugar.com)
• Pour rolled oats and protein powder into a food processor. (popsugar.com)

Homologous3

• We'll use the human muscle creatine kinase protein (NP_001815.2) to find homologous proteins in the RefSeq protein database. (nih.gov)
• Notice that this is the classic use of BLAST, identifying homologous proteins. (nih.gov)
• These two large proteins are homologous in structure and are cofactors, not enzymes, in the clotting process. (medscape.com)

Genes8

• Our laboratory identified a novel subfamily of Krüppel-like zinc finger proteins referred to as GLI-Similar or GLIS, which consists of three related genes referred to as GLIS1, GLIS2 and GLIS3. (nih.gov)
• GLIS proteins bind specific DNA elements-known as GLIS-binding sites (GLIS BS)-in the regulatory region of target genes and function as regulators of gene expression. (nih.gov)
• Because of the presence of multiple related proteins (paralogs) in the various species, the resulting tree shows both the phylogeny of the species and the phylogeny of the different genes and their products. (nih.gov)
• There are four distinct kinds of proteins here (U, M, S, and B). These are the products of different genes (paralogs) in human. (nih.gov)
• There are five sequences though because there are two separate genes on chromosome 15 that produce the U-type proteins. (nih.gov)
• Bait (BD-X) + Prey (AD-Y) = Transcription of reporter genes and form a functional Gal4 TF = Protein products = yeast growth in selective media Limitations: 1. (slideshare.net)
• Mutations in the genes that code for these proteins are common in several types of cancer. (cancer.gov)
• Utilize the protein AQUA™ technique to measure expression of silenced genes, quantitate protein levels for low abundance serum proteins and analyze phosphorylated peptides enriched with immobilized metal affinity chromatography. (sigmaaldrich.com)

Carbs5

• A 33-gram (1.16-ounce) scoop of standard casein protein powder contains 24 grams of protein, 3 grams of carbs and 1 gram of fat ( 4 ). (healthline.com)
• In the infamous Bray overfeeding study, participants were overfed high protein, medium protein, and low protein (in exchange with fat, so carbs were the same across groups). (patreon.com)
• So theoretically, the excess insulin load which may have occurred with high protein vs. low protein (with similar carbs) didn't cause extra fat accumulation. (patreon.com)
• When you need a quick post-workout snack, something with protein and carbs, look no further. (popsugar.com)
• At 47 calories per ball, a three-piece serving is 141 calories and offers 8.1 grams of protein and 24 grams of carbs. (popsugar.com)

Biologically1

• These results show that the recombinant proteins are biologically active. (nature.com)

Predominantly2

• Protein S functions predominantly as a nonenzymatic cofactor for the action of another anticoagulant protein, activated protein C (APC). (medscape.com)
• As the hair cells matured, the two proteins localized predominantly to the stereocilia tips. (nih.gov)

Conformation2

• In some instances, however, the breaking of a key bond could be followed by the complete breakdown of the conformation of the native protein. (britannica.com)
• If denaturation can be brought about easily and if renaturation is difficult, how is the native conformation of globular proteins maintained in living organisms, in which they are produced stepwise, by incorporation of one amino acid at a time? (britannica.com)

Digestion5

• One study tested digestion speed by providing participants with either a casein or whey protein shake . (healthline.com)
• They found that circulating levels of leucine rose 25% higher in the whey protein group, indicating faster digestion ( 8 ). (healthline.com)
• It reduces protein breakdown within the body due to its slow digestion rate and sustained supply of amino acids to muscle cells. (healthline.com)
• Although many native proteins are resistant to the action of the enzyme trypsin, which breaks down proteins during digestion , they are hydrolyzed by the same enzyme after denaturation. (britannica.com)
• Protein identification typically involves chemical or enzymatic digestion of proteins into peptides, which are then analyzed by mass spectrometry and identified using computational methods or sequencing. (sigmaaldrich.com)

Mechanisms2

• Protein S is part of a system of anticoagulant proteins that regulate normal coagulation mechanisms in the body. (medscape.com)
• As technologies for probing the spatiotemporal resolution of biomolecules have become increasingly sophisticated, so has our understanding of the diverse structural and molecular mechanisms of allosteric proteins. (nih.gov)

Cellular4

• RESEARCH OBJECTIVES Membrane proteins play a crucial role in many cellular and physiological processes. (nih.gov)
• Using powerful microscopy techniques, a research team led by scientists at the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health (NIH), has pinpointed in mice the precise cellular location of two proteins known to be important for hearing and balance. (nih.gov)
• Ranum said further research is needed, and it will be important to understand how these proteins are being made without the normal cellular signals and if strategies to block their production can be developed. (eurekalert.org)
• The study of allostery has a central place in biology because of the myriad roles of allosteric proteins in cellular function. (nih.gov)

Cytoskeletal2

• Here, we identified actin-binding cytoskeletal crosslinking proteins filamin A (FLNa) and B (FLNb) as important regulators of both EBOV and MARV entry. (nih.gov)
• Additionally, in collaboration with colleagues, Dr. Tjandra is studying how the assembly of the cytoskeletal protein actin is regulated. (nih.gov)

Denaturation4

• The denaturation of the proteins of egg white by heat-as when boiling an egg-is an example of irreversible denaturation. (britannica.com)
• Finally, denaturation can also be accomplished by exposing proteins to organic solvents such as ethanol or acetone . (britannica.com)
• Although denaturation had long been considered an all-or-none reaction, it is now thought that many intermediary states exist between native and denatured protein. (britannica.com)
• The peptide bonds that can be split by trypsin are inaccessible in the native proteins but become accessible during denaturation. (britannica.com)

Biochemistry1

• The Protein Expression Facility is an integrated partner of the Biochemistry and Biophysics Center, dedicated to all things protein-related. (nih.gov)

Post-translational1

• 2. Proteins, requiring post-translational modifications, are not suitable to study using this method. (slideshare.net)

Purification1

• Its mission is to offer assistance to its members, as well as outside collaborators, in the form of, but not restricted to: custom plasmid design, large scale fermentation, protein purification, biochemical characterization, and biophysical quality control. (nih.gov)

Powder3

• Chocolate-flavored protein powder adds extra flavor and, obviously, takes the nutrient count up a notch. (allrecipes.com)
• We've asked the boys behind Neat Nutrition, a new 'clean' boutique protein powder, for some help. (askmen.com)
• A benefit of this is that Neat Nutrition's protein powder can be digested easily and will not cause blood sugar levels to spike. (askmen.com)

Adding protein powders1

• Still, taking protein supplements or adding protein powders to foods, shakes or smoothies is a popular trend for growing children and teenagers. (clevelandclinic.org)

Physiological3

• These proteins play a critical role in a number of physiological functions and have been implicated in several pathologies. (nih.gov)
• To understand how thrombosis occurs in protein S deficiency, its physiological function should be briefly reviewed. (medscape.com)
• Admittedly, I'm still interested in the physiological/nutrient partitioning effects of high protein in the context of overeating. (patreon.com)

Amount of protein3

• This means that the casein group reduced the total amount of protein burned for fuel over a seven-hour period. (healthline.com)
• In brief, the protein leverage hypothesis (PLH) states that an animal will keep eating until a certain amount of protein has been ingested. (patreon.com)
• Find the correct amount of protein consumption for your gender and age. (familyeducation.com)

Amino acid2

• protein was identical to the common form encephalopathy (BSE) is a In accordance with the guidelines bovine PrP amino acid sequence (as feed-borne prion disease that affects of the World Organisation for Animal translated from GenBank accession mainly cattle but also other ruminants, Health ( 5 ), BSE was confi rmed for no. (cdc.gov)
• Disulphide bonds  Disulfide bonds are the links between the sulfur atoms of 2 cysteine amino acid residues in proteins. (slideshare.net)

Cytoplasm1

• The team, which included Krishna Kumar Haridhasapavalan and Pradeep Kumar Sundaravadivelu, found that the proteins entered the cells' cytoplasm and eventually reached the nuclei. (nature.com)

Gene6

• This database contains coding region translations for selected RefSeq Select transcripts for human, mouse, and rat - one per gene - as well as RefSeq prokaryotic genome protein annotations. (nih.gov)
• Remove the organism limit and use both the exclude XP_ and WP_ options to exclude gene models and the RefSeq prokaryotic proteins. (nih.gov)
• Evidence for arterial thrombosis in other hereditary thrombophilias (eg, protein C deficiency, antithrombin III deficiency, or factor V Leiden gene mutation) also appears to be minimal. (medscape.com)
• The disease stems from a genetic mutation in the Huntingtin gene that produces too many copies of a DNA segment known as CAG, which gives rise to a longer Huntingtin protein with toxic effects. (eurekalert.org)
• To overcome this, scientists led by Rajkumar P. Thummer artificially synthesised gene sequences that encode six proteins - GATA4, MEF2C, TBX5, ETS2, MESP1 and HAND2. (nature.com)
• The gene sequences overexpressed the recombinant proteins in the bacterial cells. (nature.com)

Sequences2

• Notice that the U and S proteins don't align at the N-terminal because of their signal peptide sequences. (nih.gov)
• These settings restrict the RefSeq proteins to non-model RefSeqs that are based on submitted transcript sequences that have good experimental support. (nih.gov)

Characterization1

• Compared to other techniques used for the large-scale characterization of proteins, mass spectrometry has become a primary tool for proteomics based on its amenability to complex analysis. (sigmaaldrich.com)

Powders2

• Many protein powders contain stimulants or substances that can take a toll on your child's digestive system . (clevelandclinic.org)
• Traditionally, what ingredients should you watch out for in protein powders? (askmen.com)

High protein8

• High protein levels can cause kidney stones and make the kidneys work harder to filter out waste products. (clevelandclinic.org)
• A high-protein diet wears the kidneys out over time, and contributes to dehydration. (clevelandclinic.org)
• it it's a high protein diet, it will require less food and may lead to weight loss. (patreon.com)
• Tl;dr: if you're overeating, and most people usually are, best make it high protein. (patreon.com)
• In this study, the high protein group packed on muscle mass. (patreon.com)
• Thus, if you're overeating, and most people usually are, best make it high protein. (patreon.com)
• Also, watch out for " high-protein" diets, which promise quick weight loss by encouraging large amounts of protein while severely limiting carbohydrate intake (no bread, potatoes, rice, pasta, cereal, and so on). (familyeducation.com)
• You might lose weight, but not from any magical combination of "high protein/low carbohydrates. (familyeducation.com)

Enzymatic2

• In one of many examples of nature's efficiency, the same enzyme that clots blood, thrombin, is converted from clotting to an anticoagulant mechanism on the surface of the endothelium and it then activates protein C to its active enzymatic form, APC. (medscape.com)
• APC requires protein S as a cofactor in its enzymatic action on its 2 substrates, FVa and FVIIIa. (medscape.com)

Target protein1

• In publications in the journal Science last year and this year, Subramaniam and his team reported resolutions of 2.2 angstroms and 2.3 angstroms in cryo-EM with larger proteins, including a complex of a cancer target protein with a small molecule inhibitor. (cancer.gov)

Search2

• Or go to the BLAST homepage and select Protein BLAST search and enter the accession number. (nih.gov)
• The protein Graphic summary also shows the results for a Conserved Domain Database search that searches a database of position specific score matrices and identifies conserved domains in the query sequence. (nih.gov)

Molecular4

• Molecular typing of the pathologic prion protein from 2 cows with bovine spongiform medulla oblongata was tested and encepalopathy (BSE), Switzerland. (cdc.gov)
• The findings are significant because these newly identified mutant proteins kill neurons and build up in regions of the brain that are most affected by the disease, said Laura Ranum, Ph.D., director of the UF Center for NeuroGenetics and a professor in the UF College of Medicine department of molecular genetics and microbiology. (eurekalert.org)
• PPI  Permanent complexes  When an association between proteins is highly stable and need help from molecular switches to break them, they are permanent complexes. (slideshare.net)
• Understanding the molecular "rules" governing allostery would elucidate the molecular basis of dysfunction in disease-associated allosteric proteins, provide a means for designing tailored therapeutics, and enable the design of new sensors and enzymes for synthetic biology. (nih.gov)

Whey protein6

• Effect of Whey Protein Supplementation in Postmenopausal Women: A Systematic Review and Meta-Analysis. (nih.gov)
• Casein protein is digested slowly, while whey protein digested quickly. (healthline.com)
• One consumed whey protein and the other had no protein. (healthline.com)
• We have found that many people are surprised that whey protein comes from cow's milk. (askmen.com)
• At this stage, whey protein is in liquid form. (askmen.com)
• For example, Neat Nutrition's Whey Protein has 24g of protein in a 30g scoop, giving an 80% yield. (askmen.com)

Gels2

• This protocol is for electrically eluting pure proteins from SDS-page gels. (nih.gov)
• This photograph shows Yumi Yamashita, Ph.D., working with acryl amide gels to separate proteins after electropheresis. (nih.gov)

Organisms1

• We have 98 database sequence matches for a number of proteins and organisms. (nih.gov)

Biological3

• Design of allosteric proteins with new function is essential for engineering biological systems. (nih.gov)
• A common property of denatured proteins, however, is the loss of biological activity-e.g., the ability to act as enzymes or hormones . (britannica.com)
• Protein mass spectrometry is widely used to analyze biological samples for biomarker discovery, proteomics research, and clinical applications. (sigmaaldrich.com)

Intake6

• Dietary protein intake and all-cause mortality: results from The Kawasaki Aging and Wellbeing Project. (nih.gov)
• Longitudinal association between dietary protein intake and survival in peritoneal dialysis patients. (nih.gov)
• In fact, excessive protein intake doesn't lead to more muscle development, but instead can put stress on their liver and kidneys and increase the risk for dehydration. (clevelandclinic.org)
• Ten to 30% of your calorie intake should come from protein," says the Food and Nutrition Board, Institute of Medicine, National Academy of Sciences . (clevelandclinic.org)
• They might need 10-15% more protein intake to get the same benefits as meat-eaters," Schnee says. (clevelandclinic.org)
• As demand grows for alt-proteins, food science and technology solutions will play a critical role in enhancing protein and associated product properties that can lead to increased options for consumers looking to diversify their diets or take a flexitarian approach to protein intake. (ift.org)

Biochemical1

• Hetero-trimeric G protein (Gα, Gβγ and GDP)  Transient complexes  When a protein interacts briefly and in a reversible manner with other proteins in only certain biochemical cascade, they form transient complexes. (slideshare.net)

Confocal1

• The optical properties of the nanodiamond-protein complex arrays were characterized by a high throughput confocal microscope. (springer.com)

Complexes2

• In particular, he wants to improve the ability of NMR to study protein complexes in their proper context, i.e. as part of multi-component systems in complex lipid environments. (nih.gov)
• Interacting Complexes  Obligate partners  If proteins cannot exist in free form and only stable in multimeric association, they form obligate oligomers. (slideshare.net)

Pathologic2

• Whenever procoagulant forces are locally activated to form a physiologic or pathologic clot, protein S participates as part of one mechanism of controlling clot formation. (medscape.com)
• region of the prion protein was resistant fragment of the pathologic cdc.gov/EID/pdfs/18/1/11-1225- present in these abberant PrPres prion protein (PrPres): the classic type Techapp.pdf). (cdc.gov)

Fluorescent2

• They have also used detection of fluorescent signals to demonstrate loss of binding of an inhibitor protein to LRRK2 when LRRK2 is activated. (nih.gov)
• Much of what we have known previously about LRRK2 comes from overexpression studies, where cells are forced to make much more of the protein than they would normally," said Dr. Greenamyre "Our fluorescent assay reveals where LRRK2 is active in the brain and the relative level of activity without potential side effects from overexpression. (nih.gov)

Biomolecule1

• The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically. (springer.com)

Experiments2

• We anticipate that information derived from the experiments with Zip14, and perhaps other ZIP proteins, will be relevant to disorders of iron metabolism. (nih.gov)
• Lab-based experiments show that six specific recombinant proteins are capable of converting healthy skin cells, or any other type of human cell, into heart cells 1 , 2 . (nature.com)

Uptake2

• Membrane proteins are the targets of a large number of pharmacologically and toxicologically active substances and are responsible, in part, for their uptake, metabolism, and clearance. (nih.gov)
• In the fourth aim, the iron transport activity of all mammalian ZIP proteins will be systematically assessed by overexpressing the proteins and measuring the uptake of radiolabeled iron. (nih.gov)

Dietary1

• There are special cases in which a child might need additional dietary protein. (clevelandclinic.org)

Arginine2

• There are several different creatine kinase proteins and the related arginine kinases from invertebrate. (nih.gov)
• Similarly, denatured proteins give more intense colour reactions for tyrosine, histidine , and arginine than do the same proteins in the native state. (britannica.com)

Crucial role1

• Protein also plays a crucial role in keeping the immune and digestive systems healthy and happy, and can help to regulate blood pressure. (askmen.com)

Meat7

• Overall, children should get enough protein every day for basic needs and athletics if they eat two servings of lean protein, such as lean beef, pork, poultry, fish, Greek yogurt or meat alternatives. (clevelandclinic.org)
• Children who don't eat meat often have lower protein levels. (clevelandclinic.org)
• In a recent analysis, the highest percentage of greenhouse gas emissions per 100 g of protein are associated with the production of animal meat, including beef, prawns, lamb, and pork, respectively ( Poore and Nemecek 2018 ). (ift.org)
• In a recent survey conducted by the HSG FoodTech Lab at The University of St. Gallen, 54% of consumers indicated they are willing to replace meat with alternative protein sources. (ift.org)
• Plant-based proteins are most widely used to produce meat analogues. (ift.org)
• For example, Impossible Burger utilizes protein from soy, whereas Beyond Meat incorporates peas, mung beans, and brown rice as protein sources. (ift.org)
• Protein is found in many foods such as meat, dairy, nuts and beans. (askmen.com)

Bind1

• Protein-packed peanut butter helps bind the balls together. (allrecipes.com)

Facilitate1

• The major function of protein S is as a cofactor to facilitate the action of activated protein C (APC) on its substrates, activated factor V (FVa) and activated factor VIII (FVIIIa). (medscape.com)

Ligands1

• This is a great tool, easy to visualize protein structure, with and without ligands. (merlot.org)

Dairy2

• Casein is a slow-digesting dairy protein that people often take as a supplement. (healthline.com)
• This is an important difference between these two popular dairy proteins. (healthline.com)

Atomic2

• and 2) To encourage additional research to further develop methods for studying the structure of membrane proteins at atomic resolution. (nih.gov)
• Rapid advances in cryo-EM technology, from left to right, show improving resolutions in atomic detail of proteins and drug binding sites. (cancer.gov)

Specific3

• Dr. Tjandra is studying how viral proteins aggregate into specific shapes (e.g. eicosahedral or conical) and how that organization relates to viral function. (nih.gov)
• Functionally normal membrane proteins are vital to health and specific defects are associated with many known disease states. (nih.gov)
• PPI are often mediated by the proteins having a specific quaternary structure. (slideshare.net)

Isolation1

• The technological challenges associated with algal proteins include off-flavors, lower digestibility due to the wall structure of the cells, and high manufacturing costs, most notably those related to the isolation of protein from algal biomass ( Bleakley and Hayes 2017 ). (ift.org)

Consume2

• They might consume less protein than other children, but they likely still meet their nutritional needs," she says. (clevelandclinic.org)
• Although animal-derived proteins constitute the majority of the protein we consume, there is a strong movement in the industry towards plant-derived proteins which can satisfy the same requirement with arguably less environmental impact. (anuga.com)

Electron3

• However, in the recent past, advances in methods for crystallization and analysis of proteins by x-ray and electron diffraction methods, and improvements in NMR methods, have led to new opportunities. (nih.gov)
• The techniques of x-ray or electron diffraction and of NMR spectroscopy have been emphasized in this announcement, since they presently show the most promise for producing the most complete high resolution information for the largest number of proteins. (nih.gov)
• Scientists using a technology called cryo-EM (cryo-electron microscopy) have broken through a technological barrier in visualizing proteins with an approach that may have an impact on drug discovery and development. (cancer.gov)