Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Prostheses and Implants: Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.Joint Prosthesis: Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)Knee Prosthesis: Replacement for a knee joint.Hip Prosthesis: Replacement for a hip joint.Penile Prosthesis: Rigid, semi-rigid, or inflatable cylindric hydraulic devices, with either combined or separate reservoir and pumping systems, implanted for the surgical treatment of organic ERECTILE DYSFUNCTION.Heart Valve Prosthesis: A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Artificial Limbs: Prosthetic replacements for arms, legs, and parts thereof.Visual Prosthesis: Artificial device such as an externally-worn camera attached to a stimulator on the RETINA, OPTIC NERVE, or VISUAL CORTEX, intended to restore or amplify vision.Prosthesis Implantation: Surgical insertion of a prosthesis.Prosthesis Fitting: The fitting and adjusting of artificial parts of the body. (From Stedman's, 26th ed)Neural Prostheses: Medical devices which substitute for a nervous system function by electrically stimulating the nerves directly and monitoring the response to the electrical stimulation.Ossicular Prosthesis: An implant used to replace one or more of the ear ossicles. They are usually made of plastic, Gelfoam, ceramic, or stainless steel.Dental Prosthesis: An artificial replacement for one or more natural teeth or part of a tooth, or associated structures, ranging from a portion of a tooth to a complete denture. The dental prosthesis is used for cosmetic or functional reasons, or both. DENTURES and specific types of dentures are also available. (From Boucher's Clinical Dental Terminology, 4th ed, p244 & Jablonski, Dictionary of Dentistry, 1992, p643)Dental Prosthesis, Implant-Supported: A prosthesis that gains its support, stability, and retention from a substructure that is implanted under the soft tissues of the basal seat of the device and is in contact with bone. (From Boucher's Clinical Dental Terminology, 4th ed)Heart Valve Prosthesis Implantation: Surgical insertion of synthetic material to repair injured or diseased heart valves.Treatment Failure: A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.AmputeesMaxillofacial Prosthesis: A prosthetic appliance for the replacement of areas of the maxilla, mandible, and face, missing as a result of deformity, disease, injury, or surgery. When the prosthesis replaces portions of the mandible only, it is referred to as MANDIBULAR PROSTHESIS.Larynx, Artificial: A device, activated electronically or by expired pulmonary air, which simulates laryngeal activity and enables a laryngectomized person to speak. Examples of the pneumatic mechanical device are the Tokyo and Van Hunen artificial larynges. Electronic devices include the Western Electric electrolarynx, Tait oral vibrator, Cooper-Rand electrolarynx and the Ticchioni pipe.Arthroplasty, Replacement: Partial or total replacement of a joint.Eye, Artificial: A ready-made or custom-made prosthesis of glass or plastic shaped and colored to resemble the anterior portion of a normal eye and used for cosmetic reasons. It is attached to the anterior portion of an orbital implant (ORBITAL IMPLANTS) which is placed in the socket of an enucleated or eviscerated eye. (From Dorland, 28th ed)Penile Implantation: Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.Prosthesis-Related Infections: Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Serial Publications: Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)Phentermine: A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.Pergolide: A long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.Surgical Procedures, Minimally Invasive: Procedures that avoid use of open, invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device.Serotonin 5-HT2 Receptor Agonists: Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT2 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT2 receptor subtypes.Fenfluramine: A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.Technetium Tc 99m Medronate: A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Osseointegration: The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).Denture Retention: The retention of a denture in place by design, device, or adhesion.Denture, Partial, Removable: A partial denture designed and constructed to be removed readily from the mouth.Fracture Fixation, Intramedullary: The use of nails that are inserted into bone cavities in order to keep fractured bones together.Hip Joint: The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.Arthroplasty, Replacement, Hip: Replacement of the hip joint.Intervertebral Disc: Any of the 23 plates of fibrocartilage found between the bodies of adjacent VERTEBRAE.Intervertebral Disc Displacement: An INTERVERTEBRAL DISC in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.Electronics: The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Gas PoisoningIntervertebral Disc Degeneration: Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.Total Disc Replacement: The replacement of intervertebral discs in the spinal column with artificial devices. The procedure is done in the lumbar or cervical spine to relieve severe pain resulting from INTERVERTEBRAL DISC DEGENERATION.

Radiolucent lines and component stability in knee arthroplasty. Standard versus fluoroscopically-assisted radiographs. (1/2728)

The radiolucent lines and the stability of the components of 66 knee arthroplasties were assessed by six orthopaedic surgeons on conventional anteroposterior and lateral radiographs and on fluoroscopic views which had been taken on the same day. The examiners were blinded as to the patients and clinical results. The interpretation of the radiographs was repeated after five months. On fluoroscopically-assisted radiographs four of the six examiners identified significantly more radiolucent lines for the femoral component (p < 0.05) and one significantly more for the tibial implant. Five examiners rated more femoral components as radiologically loose on fluoroscopically-assisted radiographs (p = 0.0008 to 0.0154), but none did so for the tibial components. The mean intra- and interobserver kappa values were higher for fluoroscopically-assisted radiographs for both components. We have shown that fluoroscopically-assisted radiographs allow more reproducible, and therefore reliable, detection of radiolucent lines in total knee arthroplasty. Assessment of the stability of the components is significantly influenced by the radiological technique used. Conventional radiographs are not adequate for evaluation of the stability of total knee arthroplasty and should be replaced by fluoroscopically-assisted films.  (+info)

Analysis of 118 second-generation metal-on-metal retrieved hip implants. (2/2728)

Osteolysis is due to particulate wear debris and is responsible for the long-term failure of total hip replacements. It has stimulated the development of alternative joint surfaces such as metal-on-metal or ceramic-on-ceramic implants. Since 1988 the second-generation metal-on-metal implant Metasul has been used in over 60 000 hips. Analysis of 118 retrieved specimens of the head or cup showed rates of wear of approximately 25 microm for the whole articulation per year in the first year, decreasing to about 5 microm per year after the third. Metal surfaces have a 'self-polishing' capacity. Scratches are worn out by further joint movement. Volumetric wear was decreased some 60-fold compared with that of metal-on-polyethylene implants, suggesting that second-generation metal-on-metal prostheses may considerably reduce osteolysis.  (+info)

Migration of the Duraloc cup at two years. (3/2728)

We carried out 71 primary total hip arthroplasties using porous-coated, hemispherical press-fit Duraloc '100 Series' cups in 68 consecutive patients; 61 were combined with the cementless Spotorno stem and ten with the cemented Lubinus SP II stem. Under-reaming of 2 mm achieved a press-fit. Of the 71 hips, 69 (97.1%) were followed up after a mean of 2.4 years. Migration analysis was performed by the Ein Bild Rontgen Analyse method, with an accuracy of 1 mm. The mean total migration after 24 months was 1.13 mm. Using the definition of loosening as a total migration of 1 mm, it follows that 30 out of 63 cups (48%) were loose at 24 months.  (+info)

Survivorship and radiological analysis of the standard Souter-Strathclyde total elbow arthroplasty. (4/2728)

We undertook a radiological analysis of 186 standard Souter implants to determine survivorship and to analyse the pattern of failure in those needing revision. The implants had been inserted as a primary procedure in patients with rheumatoid arthritis of the elbow at our hospital over the last 12 years. Taking revision as an endpoint, the survivorship after 12 years was 87%. If, however, revision and loosening, defined as the Hindex value equivalent to demarcation of 1 mm around the whole implant, are also included, the survivorship falls to 80%. Of the 24 implants revised, 18 (75%) were for problems with the humeral component, three (12.5%) with the ulnar component and three (12.5%) for instability. Loosening of the humeral component occurred when the implant extended into the humerus, with the tip moving anteriorly on to the anterior humeral cortex. Our study indicates that loosening can be predicted by the rate of change in this angle of extension of the prosthesis.  (+info)

Cement migration after THR. A comparison of charnley elite and exeter femoral stems using RSA. (5/2728)

Studies using roentgen stereophotogrammetric analysis (RSA) have shown that the femoral components of cemented total hip replacements (THR) migrate distally relative to the bone, but it is not clear whether this occurs at the cement-implant or the cement-bone interface or within the cement mantle. Our aim was to determine where this migration occurred, since this has important implications for the way in which implants function and fail. Using RSA we compared for two years the migration of the tip of the stem with that of the cement restrictor for two different designs of THR, the Exeter and Charnley Elite. We have assumed that if the cement restrictor migrates, then at least part of the cement mantle also migrates. Our results have shown that the Exeter migrates distally three times faster than the Charnley Elite and at different interfaces. With the Exeter migration was at the cement-implant interface whereas with the Charnley Elite there was migration at both the cement-bone and the cement-implant interfaces.  (+info)

Subsidence of a non-polished stem in revisions of the hip using impaction allograft. Evaluation with radiostereometry and dual-energy X-ray absorptiometry. (6/2728)

We revised 24 consecutive hips with loosening of the femoral stem using impaction allograft and a cemented stem with an unpolished proximal surface. Repeated radiostereometric examinations for up to two years showed a slow rate of subsidence with a mean of 0.32 mm (-2.0 to +0.31). Fifteen cases followed for a further year showed the same mean subsidence after three years, indicating stabilisation. A tendency to retroversion of the stems was noted between the operation and the last follow-up. Retroversion was also recorded when displacement of the stem was studied in ten of the patients after two years. Repeated determination of bone mineral density showed an initial loss after six months, followed by recovery to the postoperative level at two years. Defects in the cement mantle and malalignment of the stem were often noted on postoperative radiographs, but did not correlate with the degrees of migration or displacement. After one year, increasing frequency of trabecular remodelling or resorption of the graft was observed in the greater trochanter and distal to the tip of the stem. Cortical repair was noted distally and medially (Gruen regions 3, 5 and 6). Migration of the stems was the lowest reported to date, which we attribute to the improved grafting technique and to the hardness of the graft.  (+info)

Induction of macrophage C-C chemokine expression by titanium alloy and bone cement particles. (7/2728)

Particulate wear debris is associated with periprosthetic inflammation and loosening in total joint arthroplasty. We tested the effects of titanium alloy (Ti-alloy) and PMMA particles on monocyte/macrophage expression of the C-C chemokines, monocyte chemoattractant protein-1 (MCP-1), monocyte inflammatory protein-1 alpha (MIP-1alpha), and regulated upon activation normal T expressed and secreted protein (RANTES). Periprosthetic granulomatous tissue was analysed for expression of macrophage chemokines by immunohistochemistry. Chemokine expression in human monocytes/macrophages exposed to Ti-alloy and PMMA particles in vitro was determined by RT-PCR, ELISA and monocyte migration. We observed MCP-1 and MIP-1alpha expression in all tissue samples from failed arthroplasties. Ti-alloy and PMMA particles increased expression of MCP-1 and MIP-1alpha in macrophages in vitro in a dose- and time-dependent manner whereas RANTES was not detected. mRNA signal levels for MCP-1 and MIP-1alpha were also observed in cells after exposure to particles. Monocyte migration was stimulated by culture medium collected from macrophages exposed to Ti-alloy and PMMA particles. Antibodies to MCP-1 and MIP-1alpha inhibited chemotactic activity of the culture medium samples. Release of C-C chemokines by macrophages in response to wear particles may contribute to chronic inflammation at the bone-implant interface in total joint arthroplasty.  (+info)

Cytokine levels in synovial fluid from hips with well-functioning or loose prostheses. (8/2728)

We analysed synovial fluid from 88 hips, 38 with osteoarthritis and 12 with well-functioning and 38 with loose hip prostheses. The levels of TNF-alpha, IL-1beta (71 hips) and IL-6 (45 hips) were measured using the ELISA technique. Joints with well-functioning or loose prostheses had significantly increased levels of TNF-alpha compared with those with osteoarthritis. Hips with aseptic loosening also had higher levels of IL-1beta but not of IL-6 compared with those without an implant. The levels of TNF-alpha and IL-1beta did not differ between hips with stable and loose prostheses. Higher levels of TNF-alpha were found in hips with bone resorption of type II and type III (Gustilo-Pasternak) compared with those with type-I loosening. The level of cytokines in joint fluid was not influenced by the time in situ of the implants or the age, gender or area of the osteolysis as measured on conventional radiographs. Our findings support the theory that macrophages in the joint capsule increase the production of TNF-alpha at an early phase probably because of particle load and in the absence of clinical loosening. Since TNF-alpha has an important role in the osteolytic process, the interfaces should be protected from penetration of joint fluid.  (+info)

  • By placing one or more ovoid resilient prosthetic nuclei in series inside a peanut-shaped housing of metal ceramic or polymeric material, which housing is shaped so that it is separated into two sections longitudinally, a thin profile prosthesis can be created which will allow placement of the device through a small opening for implant into the thoracic or lumbar portion of the spine. (
  • In cases involving full-arch implant-supported restorations, late implant failure can be particularly catastrophic due to the implant failure's impact on the prosthetic component of treatment. (
  • Loosening of the fixation of the implant and the fatigue failure of prosthetic stems create problems for both patient and surgeon. (
  • The Osseoanchored Prostheses for the Rehabilitation of Amputees (OPRA) device instead uses fixtures and screws implanted into the patient's remaining thigh bone to connect an external prosthetic limb. (
  • Based on the work of Per-Ingvar Brånemark, who coined the term "osseointegration" with the development of dental implants, the basic prosthetic design consists of an internal intramedullary component, a transcutaneous component, and a detachable external prosthesis [ 5 ]. (
  • NTM prosthetic joint surgical site infections are associated with severe disease and require debridement, prosthesis excision, and prolonged administration of intravenous and broad spectrum antimicrobial drugs before prosthesis reimplantation ( 3 , 4 ). (
  • A penile prosthesis is another treatment option for men with erectile dysfunction ( ED ). These devices are either malleable or inflatable. (
  • Sometimes a penile prosthesis is implanted during surgery to reconstruct the penis when scarring has caused erections to curve (Peyronie's disease). (
  • How Does the Penile Prosthesis Work? (
  • The inflatable penile prosthesis consists of two cylinders -- a reservoir and a pump -- which are placed surgically in the body. (
  • While men who have had the prosthesis surgery can see the small surgical scar where the bottom of the penis meets the scrotal sac, other people probably will be unable to tell that a man has an inflatable penile prosthesis. (
  • A penile prosthesis does not change sensation on the skin of the penis or a man's ability to reach orgasm . (
  • Once a penile prosthesis is put in, however, it may destroy the natural erection reflex. (
  • A penile prosthesis, or penile implant, is a medical device which is surgically implanted within the corpora cavernosa of the penis during a surgical procedure. (
  • Less commonly, a penile prosthesis may also be used in the final stage of plastic surgery phalloplasty to complete female to male gender reassignment surgery as well as during total phalloplasty for adult and child patients that need male genital modification. (
  • Sometimes a penile prosthesis is implanted during surgery to alter, construct or reconstruct the penis in phalloplasty. (
  • The British Journal of Urology International reports that unlike metoidioplasty for female to male sexual reassignment patients, which may result in a penis that is long but narrow, current total phalloplasty neophallus creation using a musculocutaneous latissimus dorsi flap could result in a long, large volume penis which enables safe insertion of any type of penile prosthesis. (
  • This same technique enables male victims of minor to serious iatrogenic, accidental or intentional penile trauma injuries (or even total emasculation) caused by accidents, child abuse or self-mutilation to have penises suitable for penile prosthesis implantation enabling successful sexual intercourse. (
  • There are two primary types of penile prosthesis: noninflatable, semirigid devices and inflatable devices. (
  • Almost all implanted penile prosthesis devices perform satisfactorily for a decade or more before needing replacement. (
  • During the past decade, the application of expandable prostheses has gained remarkable attention because it improves patients' appearance and allows limb growth preventing leg length discrepancy. (
  • When scientists want to test the performance of artificial corneas, retinal implants, and other visual prostheses, they typically require patients to be outfitted with one of these devices. (
  • Some implants contain metal and are therefore capable of releasing metal particles like cobalt in patients who wear metal prostheses. (
  • To monitor potential toxicity of metal hip prostheses, an annual monitoring of patients implanted is recommended and includes clinical examination, radiological examination and blood cobalt determination. (
  • Retention of certain metabolites in the blood may contribute to cognitive impairment in patients with kidney failure, revealed a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). (
  • To investigate a potential link between retained metabolites and cognitive impairment, Manjula Kurella Tamura (Stanford University and Veterans Affairs Palo Alto) and her colleagues analyzed the blood of 141 patients with kidney failure who took tests on cognitive function. (
  • Retention of certain metabolites in the blood may contribute to cognitive impairment in patients with kidney failure. (
  • When the researchers screened for the metabolites in an additional 180 patients with kidney failure, the association between 4-hydroxyphenylacetate and impaired cognitive function was replicated. (
  • This metabolite has been previously linked to cognitive impairment in patients with liver failure and in patients with inborn errors of urea synthesis," said Dr. Tamura. (
  • A new study finds that more than 2 million kidney failure patients worldwide die prematurely every year because they can't get treatment. (
  • Late implant failures have been associated with moderate to severe bone loss, a larger number of failed implants per patient, a higher incidence in male patients, and occurrence mostly in posterior areas. (
  • For patients, late implant failure is synonymous with additional costs, procedures, and recovery time. (
  • 12 Considering that pain, cost, and recovery time are among the three key concerns for patients facing any implant procedure, 3 it behooves clinicians to familiarize themselves with simplified, cost-effective chairside procedures for salvaging implant-supported fixed full-arch prostheses for those instances when implant failures occur. (
  • CONCLUSIONS: Despite several prostheses available, most patients referred to Heart Valve Clinics and good candidate regarding their clinical profile cannot be implanted with TMVR because of mismatch between their anatomy and prosthesis characteristics. (
  • In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement, a high number experienced severe and moderate cases of prosthesis-patient mismatch--meaning the implanted heart valve is too small for the patient which can lead to inadequate blood flow. (
  • A new heart device called the MitraClip (from Abbott) has been shown to benefit patients with heart failure and reduce death rates among them significantly. (
  • Ramadan fasting can be safe for patients with heart failure, according to research presented today at the 29th Annual Conference of the Saudi Heart Association, held 1 to 3 March in Riyadh, Saudi Arabia. (
  • Some patients who underwent valve replacement with the original Starr-Edwards prosthesis in the 1960s are alive to this day. (
  • In the last 40 years more than 80 models of prostheses have been developed for patients requiring valve replacement. (
  • Some patients may not have a long enough residual limb to properly fit a socket prosthesis or may have other conditions, such as scarring, pain, recurrent skin infections, or fluctuations in the shape of the residual limb that prevent them from being able to use a prosthesis with a socket. (
  • Patients require about six months of training and rehabilitation after the second surgery, before being fitted with their own customized prosthesis by a trained prosthetist. (
  • This study examined the long-term clinical and echocardiographic effects of prosthesis-patient mismatch in patients with and without left ventricular systolic dysfunction at the time of aortic valve replacement. (
  • P = .009), and diminished left ventricular mass regression compared with patients with impaired preoperative left ventricular function and no prosthesis-patient mismatch. (
  • These effects of prosthesis-patient mismatch were not observed in patients with normal preoperative left ventricular function. (
  • Prosthesis-patient mismatch at an indexed effective orifice area of 0.85 cm2/m2 or less after aortic valve replacement primarily affects patients with impaired preoperative left ventricular function and results in decreased survival, lower freedom from heart failure, and incomplete left ventricular mass regression. (
  • Patients with impaired left ventricular function represent a critical population in whom prosthesis-patient mismatch should be avoided at the time of aortic valve replacement. (
  • Once the failure of dental implants occurs, it may cause some severe negative consequences for patients. (
  • For example, the failure will cause a financial loss for patients and a possible shock concerning both mental and physical aspects. (
  • To reduce these risks it is important and necessary for clinicians to be able to predict the risk of the failure of dental implants of individual patients before they undergo dental implant treatment. (
  • The aim of the project is to find out the possible risk factors for failure of dental implants and to develop a prediction model for the failure of dental implants at follow-up as a tool for clinicians to establish patients individual risk profile. (
  • The failure of implants is defined as the presence of peri-implantitis, presence of mobility of implants, or removal of the implants for any reasons, for instance, unacceptable performance in aspects of function, tissue physiology, esthetics, and patients' satisfaction after placement of suprastructure. (
  • Each type of the prosthesis studied was implanted in consecutive group of patients - 90 patients with BioModular ® system, 103 with the initial Nottingham TSR and 34 patients with the current Nottingham TSR system. (
  • Unambiguous presentation of data allows surgeons, patients and policy makers to directly compare commonly used prosthesis constructs to a reference construct. (
  • Calcification of either tissue leads to deterioration and, ultimately, failure causing poor quality of life and decreased overall life expectancy in patients. (
  • Uncemented total hip prostheses were introduced some 40 years ago, after disappointing results with cemented hip prostheses in young and active patients. (
  • Blacha J (2004) High osteolysis and revision rate with the hydroxyapatite- coated ABG hip prostheses: 65 hips in 56 young patients followed for 5-9 years. (
  • The purpose of our study was to evaluate an articular resurfacing prosthesis (HemiCAP ® , Arthrosurface Inc., Franklin, MA, USA) being used in middle-aged patients for focal full thickness articular cartilage lesions. (
  • Association Between Comorbidities and Outcomes in Heart Failure Patients With and Without an Implantable Cardioverter-Defibrillator for Primary Prevention. (
  • 9. The prosthesis system of claim 3 in which the augmentation devices further include devices with different angles between the proximal surface and opposed distal surface. (
  • A femoral prosthesis has load shoulders for transferring normal loading to the femur at the proximal end to reduce stress shielding. (
  • The prosthesis has a mating load shoulder in its proximal section which lands. (
  • 4. The prosthesis according to claim 9, wherein the stem has a stem length from the lower end of the distal section to the shoulder on the proximal section, measured along the stem axis, and a flexible section length of the flexible section, measured along the stem axis, the flexible section length being at least two-thirds the stem length. (
  • Fatigue behavior of titanium femoral hip prosthesis with proximal sleeve-stem modularity. (
  • Regarding Dr. Baslaim's comments, my main concern with bypassing the left and right coronary systems and tacking the valve in place would be the unpredictable steal from the proximal native coronaries if the prosthesis migrated further up and the coronary ostia were clearly below the valve. (
  • The goal of this study was to investigate whether the failure of proximal humerus locked plating can be predicted by the DensiProbe (ARI, Davos, Switzerland). (
  • The present invention relates to a system for the modification of a prosthesis so that the basic prosthesis can be used in normal surgical procedures and in which certain surfaces can also be adjusted to be used in revision knee surgery or in normal surgery when it is desired to augment the thickness of the prosthesis at various bone contact surfaces. (
  • The placement of a hip prosthesis is one of the most common orthopedic surgical procedures. (
  • Though medication and surgical techniques can help control symptoms, the only cure for heart failure is an organ transplant. (
  • Vascular prosthesis suitable for use as a surgical graft is produced by implanting a rod or tube in a living host animal such as a sheep and allowing collagenous tissue to grow on the implant to form a coherent tubular wall of collagenous tissue. (
  • 4. A method of revascularization surgery wherein a vascular prosthesis as defined in claim 1 is used as a surgical graft in a living patient. (
  • Some studies indicate a high level of patient satisfaction, attributable in part to improved technology in the prosthesis itself, improved surgical techniques making the procedure less painful, and more reasonable patient expectations. (
  • Similar extra-anatomic solutions used in extreme cases of supracoronary aortic valve placement with no native ostial compromise should always be accompanied by native ostia surgical closure (unless the grafts are placed because only a partial coronary occlusion is assumed - such as in a coronary ostium in close proximity to the valve annulus), which may not be feasible through the metal frame of the TAVR prosthesis. (
  • The followup data included condition of the surgical wound, infection, neurological deficit, range of movement, stability of the prosthesis in axial compression and varus/valgus stress, severity of pain, shift of the implant tip, and failure of the prosthesis. (
  • One-stage surgical revision involves prosthesis removal, debridement, antibiotic treatment and joint replacement in the same surgical operation. (
  • Such infections can result from inoculation of the surgical field or prosthesis during a surgical or medical procedure or from environmental contamination during the early postoperative period ( 5 ). (
  • In one aspect of the present invention, the implantation of the prosthesis allows for occluding fluid to weep from the prosthesis and into a sac of an aneurysm to cause occlusion thereof without introducing the occluding fluid into the blood stream. (
  • Angiogenesis by bFGF is important for endothelialization in vascular prostheses and is significant from shortly after implantation. (
  • Antithrombogenicity is important when the diameter of vascular prostheses become small for satisfactory patency. (
  • Collateral formation in ischemic heart disease is induced by angiogenic factors including bFGF.We hypothesized that tissue-fragmented (TF-) grafts are rich of angiogenic activity from shortly after implantation and it ability may work for collateral formation to the ischemic area when it is used for a small diameter vascular prosthesis in the coronary artery position. (
  • These results demonstrated that endogenous bFGF is important for endothelialization due to angiogenesis in fabric vascular prostheses, whereas thrombus and infection might have a negative effect. (
  • Publications] Tomizawa Y: 'Endogenous basic fibroblast growth factor for endothelialization due to angiogenesis in fabric vascular prostheses' ASAIO J. 42. (
  • The implant is subsequently removed and the tubular wall of collagenous tissue is stripped from the rod or tube and tanned in glutaraldehyde to serve as a vascular prosthesis. (
  • AbstractObjectivesTo investigate the impact of the introduction of the next generation self ‐expanding (SE) and balloon‐expandable (BE) transcatheter heart valves (THVs) on the incidence of prosthesis-patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR).BackgroundPPM is a risk factor for accelerated degeneration of bioprosthetic aortic valves. (
  • The effect of prosthesis-patient mismatch on clinical outcome and left ventricular mass regression after aortic valve replacement remains controversial. (
  • Data on whether the clinical effect of prosthesis-patient mismatch depends on left ventricular function at the time of aortic valve replacement are lacking. (
  • The authors report a case of early migration of a self-expanding transcatheter aortic valve prosthesis causing coronary obstruction and myocardial infarction. (
  • Thirty-two days later she presented with acute angina, ruled-in for myocardial infarction, and was found to have iatrogenic coronary obstruction from the aortic valve prosthesis due to cephalad migration. (
  • The purpose of this in vitro study was to evaluate the ultimate force-to-failure distal to the terminal implant of a simulated ICFDP reinforced with glass fiber compared with that of a conventionally fabricated prosthesis. (
  • 5. The prosthesis system of claim 4 in which a pawl is affixed to the cam and in which the distal surface of the augmentation device has a locking cavity to accept the pawl, said cavity having locking means on its edge to lock the pawl in a predetermined position when the pawl is rotated. (
  • If not, the challenge becomes determining whether a new implant can be placed, either at or to the mesial or distal aspect of the failed site, in addition to how best to alter the existing prosthesis so it will be acceptable to the patient in consideration of the new implant. (
  • Essentially all visual prosthesis efforts share a common principle of providing focal electrical stimulation to intact visual structures (including the retina, optic nerve, lateral geniculate nucleus (LGN) and occipital visual cortex) evoking the sensation of discrete points of light called phosphenes. (
  • The 8 million patent was issued to Second Sight Medical Products, Inc., for a visual prosthesis apparatus that enhances visual perception for people who have gone blind due to outer retinal degeneration. (
  • If CYCLOPS can use computer-enhanced images from a 50-pixel array to make its way safely through a room with a chair in one corner, a sofa along the wall, and a coffee table in the middle, then there is a good chance that a blind person with a 50-pixel retinal prosthesis would be able to do the same. (
  • Second Sight Medical Products, Inc., located in Sylmar, Calif., is a privately held company founded in 1998 by Alfred Mann, Dr. Sam Williams and Gunnar Bjorg with the goal of creating a retinal prosthesis to provide sight to subjects blinded from outer retinal degenerations, such as retinitis pigmentosa. (
  • Today, many men choose a hydraulic, inflatable prosthesis, which allows a man to have an erection whenever he chooses and is much easier to conceal. (
  • Hydraulic, inflatable prosthesis also exist and were first described in 1973 by Brantley Scott et al. (
  • The invention is directed to bioengineered graft prostheses made from two or more superimposed, chemically bonded layers of processed tissue material prepared from cleaned tissue material derived from animal sources. (
  • The bioengineered graft prostheses of the invention are prepared using methods that preserve cell compatibility, strength, and bioremodelability of the processed tissue matrix. (
  • The invention is directed to bioengineered graft prostheses prepared from cleaned tissue material derived from animal sources. (
  • This PE wear results in PE particles being distributed in the tissue surrounding the prosthesis, with macrophages being activated by these particles. (
  • What prosthesis should be used at valve re-replacement after structural valve deterioration of a bioprosthesis? (
  • Transcatheter Mitral Valve Replacement: Factors Associated with Screening Success and Failure. (
  • Choice of operation and the prosthesis used for those undergoing valve replacement is important for each individual patient and ideally should be made together by the patient, cardiologist, and surgeon. (
  • Would a CABG x2 Off-pump or on-pump-beating heart be an option if no valve malfunction, and +/- tacking suture for the prosthesis to ascending aorta? (
  • said seal being resilient and serving not only to pressurize said cement but also to control the position of the prosthesis by its shape and control the insertion depth of the prosthesis by its thickness. (
  • 11. The prosthesis inserter as claimed in claim 10 including a locator spaced away from the attachment device and adapted to engage the prosthesis to prevent axial and angular movement thereof in relation to the insertion axis of the inserter. (
  • A capa trend analysis was conducted for the reported failure mode and concluded that loosening may result from other factors not necessarily related to the device. (
  • 2. The prosthesis system of claim 1 in which the opposed surfaces of the augmentation device are angled in respect to each other. (
  • 7. The prosthesis system of claim 1 in which the mechanism to secure the augmentation device includes a lug having a beveled edge adapted to engage the edge of the recess. (
  • 10. The prosthesis inserter as claimed in claim 1 in which the pressurizer is mounted to enable pressure to be maintained on said seal when said attachment device is disconnected. (
  • 13. The prosthesis inserter as claimed in claim 11 which includes a release adapted to release the attachment device. (
  • 16. The prosthesis inserter as claimed in claim 11 in which implantation loads applied to the inserter are transmitted to the prosthesis to be implanted through the attachment device. (
  • A conventional leg prosthesis uses a specially-fitted cup-like shell called a socket that fits over the remaining portion of the patient's leg (the residual limb) to secure the device to the leg. (
  • Prostheses can help people who have lost a leg due to trauma or cancer to regain mobility and to more easily participate in everyday activities," said William Maisel, M.D., M.P.H., acting director of the Office of Device Evaluation in the FDA's Center for Devices and Radiological Health. (
  • After the second surgery, the patient works with a trained physical therapist to gradually place weight on the OPRA device using a training prosthesis. (
  • The patient was taken to the operating room where a transverse aortotomy was made at the normal anatomic site (not cephalad to the prosthesis), exposing the metal stent component of the failed device. (
  • There is no evidence of implant failure. (
  • The increased use of a novel fixed attachment system as a cost-effective approach to converting existing dentures to a fixed full-arch provisional prosthesis as well as use in a definitive fixed prosthesis has encouraging implications when clinicians are faced with salvaging full-arch fixed screw-retained restorations after late implant failure. (
  • The follow-up time is defined as the difference in time between implant placement and implant failure, or the date of the last follow-up time point if the dental implant is in an acceptable state. (
  • Methods Using a non-inferiority analysis, the performance of hip prosthesis constructs by brand were compared with the best performing contemporary construct. (
  • The quality of cementing was assessed by novel methods, the vertical and horizontal cementation index, which were statistically evaluated as predictors of failure. (
  • It might be possible to have patent grafts in the coronary position, if we could have fine basic small-diameter fabric prosthesis with good handling characteristics, excellent antithrombogenicity. (
  • Francisco, presented an overview of joint replacement therapy and reasons for their failure. (