Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Elements of limited time intervals, contributing to particular results or situations.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
An infant during the first month after birth.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The return of a sign, symptom, or disease after a remission.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Inhaling and exhaling the smoke of burning TOBACCO.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Disease having a short and relatively severe course.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Regular course of eating and drinking adopted by a person or animal.
A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Tumors or cancer of the human BREAST.
The period following a surgical operation.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.
Research techniques that focus on study designs and data gathering methods in human and animal populations.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.
A food group comprised of EDIBLE PLANTS or their parts.
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.
The confinement of a patient in a hospital.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
The period of confinement of a patient to a hospital or other health facility.
A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.
Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Stress wherein emotional factors predominate.
The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
An abnormal elevation of body temperature, usually as a result of a pathologic process.
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.
A syndrome that is characterized by the triad of severe PEPTIC ULCER, hypersecretion of GASTRIC ACID, and GASTRIN-producing tumors of the PANCREAS or other tissue (GASTRINOMA). This syndrome may be sporadic or be associated with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1.
A country spanning from central Asia to the Pacific Ocean.
The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.
Injuries incurred during participation in competitive or non-competitive sports.
That portion of the body that lies between the THORAX and the PELVIS.
The study of chance processes or the relative frequency characterizing a chance process.
The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)
Factors that can cause or prevent the outcome of interest, are not intermediate variables, and are not associated with the factor(s) under investigation. They give rise to situations in which the effects of two processes are not separated, or the contribution of causal factors cannot be separated, or the measure of the effect of exposure or risk is distorted because of its association with other factors influencing the outcome of the study.
Measurement of rate of settling of erythrocytes in anticoagulated blood.
The degree to which the individual regards the health care service or product or the manner in which it is delivered by the provider as useful, effective, or beneficial.
VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Substances that reduce the growth or reproduction of BACTERIA.
Professionals qualified by graduation from an accredited school of nursing and by passage of a national licensing examination to practice nursing. They provide services to patients requiring assistance in recovering or maintaining their physical or mental health.
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
Social and economic factors that characterize the individual or group within the social structure.
Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)
The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
Diseases caused by factors involved in one's employment.
Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, Sint Maarten, formerly included in the NETHERLANDS ANTILLES.
Breaks in bones.
Tumors or cancer of the LUNG.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Therapy with two or more separate preparations given for a combined effect.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
The beginning third of a human PREGNANCY, from the first day of the last normal menstrual period (MENSTRUATION) through the completion of 14 weeks (98 days) of gestation.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Infections by bacteria, general or unspecified.
Infection occurring at the site of a surgical incision.
Tumors or cancer of the PROSTATE.
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Hospital units providing continuous surveillance and care to acutely ill patients.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
The transference of a kidney from one human or animal to another.
Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.
The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Acquired or learned food preferences.
State of the body in relation to the consumption and utilization of nutrients.
Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)
Glucose in blood.
Raw and processed or manufactured milk and milk-derived products. These are usually from cows (bovine) but are also from goats, sheep, reindeer, and water buffalo.
The former British crown colony located off the southeast coast of China, comprised of Hong Kong Island, Kowloon Peninsula, and New Territories. The three sites were ceded to the British by the Chinese respectively in 1841, 1860, and 1898. Hong Kong reverted to China in July 1997. The name represents the Cantonese pronunciation of the Chinese xianggang, fragrant port, from xiang, perfume and gang, port or harbor, with reference to its currents sweetened by fresh water from a river west of it.
Parliamentary democracy located between France on the northeast and Portugual on the west and bordered by the Atlantic Ocean and the Mediterranean Sea.
The proportion of patients with a particular disease during a given year per given unit of population.
Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.
A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
Increase in BODY WEIGHT over existing weight.
The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.
The period during a surgical operation.
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
Voluntary cooperation of the patient in following a prescribed regimen.
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
All deaths reported in a given population.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
Systems for assessing, classifying, and coding injuries. These systems are used in medical records, surveillance systems, and state and national registries to aid in the collection and reporting of trauma.
The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.
An absence from work permitted because of illness or the number of days per year for which an employer agrees to pay employees who are sick. (Webster's New Collegiate Dictionary, 1981)
Tumors or cancer of the LIVER.
Pain during the period after surgery.
An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.
Allied health personnel who assist the professional nurse in routine duties.
Systematic collections of factual data pertaining to the diet of a human population within a given geographic area.
Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
Falls due to slipping or tripping which may result in injury.
The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.
The performance of the basic activities of self care, such as dressing, ambulation, or eating.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).

Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. (1/70469)

BACKGROUND: Since 1968 it has been known that bone marrow transplantation can ameliorate severe combined immunodeficiency, but data on the long-term efficacy of this treatment are limited. We prospectively studied immunologic function in 89 consecutive infants with severe combined immunodeficiency who received hematopoietic stem-cell transplants at Duke University Medical Center between May 1982 and September 1998. METHODS: Serum immunoglobulin levels and lymphocyte phenotypes and function were assessed and genetic analyses performed according to standard methods. Bone marrow was depleted of T cells by agglutination with soybean lectin and by sheep-erythrocyte rosetting before transplantation. RESULTS: Seventy-seven of the infants received T-cell-depleted, HLA-haploidentical parental marrow, and 12 received HLA-identical marrow from a related donor; 3 of the recipients of haploidentical marrow also received placental-blood transplants from unrelated donors. Except for two patients who received placental blood, none of the recipients received chemotherapy before transplantation or prophylaxis against graft-versus-host disease. Of the 89 infants, 72 (81 percent) were still alive 3 months to 16.5 years after transplantation, including all of the 12 who received HLA-identical marrow, 60 of the 77 (78 percent) who were given haploidentical marrow, and 2 of the 3 (67 percent) who received both haploidentical marrow and placental blood. T-cell function became normal within two weeks after transplantation in the patients who received unfractionated HLA-identical marrow but usually not until three to four months after transplantation in those who received T-cell-depleted marrow. At the time of the most recent evaluation, all but 4 of the 72 survivors had normal T-cell function, and all the T cells in their blood were of donor origin. B-cell function remained abnormal in many of the recipients of haploidentical marrow. In 26 children (5 recipients of HLA-identical marrow and 21 recipients of haploidentical marrow) between 2 percent and 100 percent of B cells were of donor origin. Forty-five of the 72 children were receiving intravenous immune globulin. CONCLUSIONS: Transplantation of marrow from a related donor is a life-saving and life-sustaining treatment for patients with any type of severe combined immunodeficiency, even when there is no HLA-identical donor.  (+info)

Chemokine mRNA expression in gastric mucosa is associated with Helicobacter pylori cagA positivity and severity of gastritis. (2/70469)

AIM: To investigate the association between the quantity of gastric chemokine mRNA expression, severity of gastritis, and cagA positivity in Helicobacter pylori associated gastritis. METHODS: In 83 dyspeptic patients, antral and corpus biopsies were taken for semiquantitative reverse transcription polymerase chain reaction (RT-PCR) and histological grading of gastritis. Gastritis was evaluated by visual analogue scales. Quantities of chemokine (IL-8, GRO alpha, ENA-78, RANTES, MCP-1) RT-PCR products were compared with G3PDH products. Each sample was also evaluated for the presence of cagA and ureA mRNA by RT-PCR. RESULTS: mRNA expression of all five chemokines was significantly greater in H pylori positive than in H pylori negative mucosa. In H pylori positive patients, in the antrum C-X-C chemokine mRNA expression was significantly greater in cagA positive patients than in cagA negative patients, but there were no significant differences in C-C chemokine mRNA expression. In H pylori positive patients, chemokine mRNA expression in the corpus was less than in the antrum. In contrast to the antrum, only GRO alpha mRNA expression was significantly greater in cagA positive infection. Polymorphonuclear cell infiltration was correlated with C-X-C chemokine mRNA expression. Significant correlations were also found between bacterial density and C-X-C chemokine mRNA expression. CONCLUSIONS: In H pylori infection, C-X-C chemokines may play a primary role in active gastritis. Infection with cagA positive H pylori induces greater gastric chemokine mRNA expression in the antral mucosa, which may be relevant to the increased mucosal damage associated with cagA positive H pylori infection.  (+info)

Reproductive factors and fatal hip fractures. A Norwegian prospective study of 63,000 women. (3/70469)

STUDY OBJECTIVE: The aim of the study was to investigate the impact of reproductive variables (age at menarche, menopause, first and last birth as well as parity, lactation, and abortions) on hip fracture mortality. DESIGN AND SETTING: A prospective study in Norway with more than 60,000 women followed up for 29 years. A total of 465 deaths as a result of hip fracture were recorded. MAIN RESULTS: Statistically significant linear relations (p < or = 0.02) were found between both age at menarche and length of reproductive period (defined as age at menopause to age at menarche) and the mortality of hip fractures in women aged less than 80. The death rate for women with a late menarche (> or = 17 years) was twice that of the women with relatively early menarche (< or = 13 years). Compared with women with less than 30 years between menopause and menarche, the mortality rate ratio in women with more than 38 reproductive years was 0.5. We also found an inverse relation with age at first birth. CONCLUSIONS: This study supports by hypothesis that an early menarche and a long reproductive period protect against hip fracture mortality. High age at first birth may also be protective.  (+info)

Postoperative tetany in Graves disease: important role of vitamin D metabolites. (4/70469)

OBJECTIVE: To test the authors' hypothesis of the causal mechanism(s) of postoperative tetany in patients with Graves disease. SUMMARY BACKGROUND DATA: Previous studies by the authors suggested that postoperative tetany in patients with Graves disease occurs during the period of bone restoration and resulted from continuation of a calcium flux into bone concomitant with transient hypoparathyroidism induced by surgery. PATIENTS AND METHODS: A prospective study was carried out to investigate sequential changes in serum levels of intact parathyroid hormone (iPTH), calcium and other electrolytes, 25-hydroxyvitamin D (25OHD), 1,25-dihydroxyvitamin D (1,25(OH)2D), and bone metabolic markers in 109 consecutive patients with Graves disease who underwent subtotal thyroidectomy. RESULTS: Preoperative serum iPTH levels negatively correlated with ionized calcium levels and positively correlated with 1,25(OH)2D or 1,25(OH)2D/25OHD. After the operation, there was a significant decline in levels of ionized calcium, magnesium, and iPTH. Serum iPTH was not detected in 15 patients after surgery. Four of these 15 patients, and 1 patient whose iPTH level was below normal, developed tetany. Preoperative serum ionized calcium levels were significantly lower, and iPTH levels were higher, in the 5 patients with tetany than in the 11 patients who did not develop tetany despite undetectable iPTH levels. The tetany group had significantly lower serum 25OHD levels and higher 1,25(OH)2D levels, and had increased 1,25(OH)2D/25OHD as an index of the renal 25OHD-1-hydroxylase activity than those in the nontetany group. These results suggest that patients with a high serum level of iPTH as a result of low serum calcium levels (secondary hyperparathyroidism) are susceptible to tetany under conditions of hypoparathyroid function after surgery. CONCLUSIONS: Postoperative tetany occurs in patients with secondary hyperparathyroidism caused by a relative deficiency in calcium and vitamin D because of their increased demand for bone restoration after preoperative medical therapy concomitant with transient hypoparathyroidism after surgery. Calcium and vitamin D supplements may be recommended before and/or after surgery for patients in whom postoperative tetany is expected to develop.  (+info)

HLA-DR expression and soluble HLA-DR levels in septic patients after trauma. (5/70469)

OBJECTIVE: To determine if cellular and soluble HLA-DR molecules may be relevant in severely injured patients for the development of gram-positive or gram-negative sepsis. SUMMARY BACKGROUND DATA: HLA-DR molecules play a central role in the specific immune response to infection. The reduced HLA-DR expression on monocytes is considered to correlate with infectious complications and the development of sepsis. Data on the role of HLA-DR expression on T cells and soluble HLA-DR molecules are rare. METHODS: HLA-DR expression on monocytes and T cells was measured by flow cytometry. Plasma levels of soluble HLA-DR were studied by enzyme-linked immunosorbent assay. RESULTS: HLA-DR expression on circulating T cells, calculated as mean fluorescence intensity in channels, was reduced at day 1 after admission in 20 patients with subsequent severe sepsis compared with 46 patients without sepsis. The septic patients immediately after trauma had significantly lower soluble HLA-DR plasma levels than the nonseptic patients. At day 2 after admission, HLA-DR expression on monocytes was significantly lower in the severe sepsis group than in the patients without sepsis, and lasted until day 14 after injury. CONCLUSIONS: In severely injured patients, decreased levels of cellular and soluble HLA-DR appear as early indicators of an immune deviation associated with the development of severe sepsis. Moreover, immune alterations of different cell types may promote distinct kinds of septicemia.  (+info)

Serum triglyceride: a possible risk factor for ruptured abdominal aortic aneurysm. (6/70469)

BACKGROUND: We aimed to determine the relationship between ruptured abdominal aortic aneurysm (AAA) and serum concentrations of lipids and apolipoproteins. METHODS: A cohort of 21 520 men, aged 35-64 years, was recruited from men attending the British United Provident Association (BUPA) clinic in London for a routine medical examination in 1975-1982. Smoking habits, weight, height and blood pressure were recorded at entry. Lipids and apolipoproteins were measured in stored serum samples from the 30 men who subsequently died of ruptured AAA and 150 matched controls. RESULTS: Triglyceride was strongly related to risk of ruptured AAA. In univariate analyses the risk in men on the 90th centile of the distribution relative to the risk in men on the 10th (RO10-90) was 12 (95% confidence interval [CI] : 3.8-37) for triglyceride, 5.5 (95% CI: 1.8-17) for apolipoprotein B (apoB) (the protein component of low density lipoprotein [LDL]), 0.15 (95% CI : 0.04-0.56) for apo A1 (the protein component of high density lipoprotein [HDL]), 3.7 (95% CI: 1.4-9.4) for body mass index and 3.0 (95% CI: 1.1-8.5) for systolic blood pressure. Lipoprotein (a) (Lp(a)) was not a significant risk factor (RO10-90 = 1.6, 95% CI: 0.6-3.0). In multivariate analysis triglyceride retained its strong association. CONCLUSION: Triglyceride appears to be a strong risk factor for ruptured AAA, although further studies are required to clarify this. If this and other associations are cause and effect, then changing the distribution of risk factors in the population (by many people stopping smoking and adopting a lower saturated fat diet and by lowering blood pressure) could achieve an important reduction in mortality from ruptured AAA.  (+info)

Respiratory symptoms and long-term risk of death from cardiovascular disease, cancer and other causes in Swedish men. (7/70469)

BACKGROUND: Depressed respiratory function and respiratory symptoms are associated with impaired survival. The present study was undertaken to assess the relation between respiratory symptoms and mortality from cardiovascular causes, cancer and all causes in a large population of middle-aged men. METHODS: Prospective population study of 6442 men aged 51-59 at baseline, free of clinical angina pectoris and prior myocardial infarction. RESULTS: During 16 years there were 1804 deaths (786 from cardiovascular disease, 608 from cancer, 103 from pulmonary disease and 307 from any other cause). Men with effort-related breathlessness had increased risk of dying from all of the examined diseases. After adjustment for age, smoking habit and other risk factors, the relative risk (RR) associated with breathlessness of dying from coronary disease was 1.43 (95% CI : 1.16-1.77), from stroke 1.77 (95% CI: 1.07-2.93), from any cardiovascular disease 1.48 (95% CI : 1.24-1.76), cancer 1.36 (95% CI : 1.11-1.67) and from any cause 1.62 (95% CI: 1.44-1.81). An independent effect of breathlessness on cardiovascular death, cancer death and mortality from all causes was found in life-time non-smokers, and also if men with chest pain not considered to be angina were excluded. An independent effect was also found if all deaths during the first half of the follow-up were excluded. Men with cough and phlegm, without breathlessness, also had an elevated risk of dying from cardiovascular disease and cancer, but after adjustment for smoking and other risk factors this was no longer significant. However, a slightly elevated independent risk of dying from any cause was found (RR = 1.18 [95% CI: 1.02-1.36]). CONCLUSION: A positive response to a simple question about effort related breathlessness predicted subsequent mortality from several causes during a follow-up period of 16 years, independently of smoking and other risk factors.  (+info)

Cardiovascular disease in insulin dependent diabetes mellitus: similar rates but different risk factors in the US compared with Europe. (8/70469)

BACKGROUND: Cardiovascular disease (CVD) in insulin dependent diabetes mellitus (IDDM) has been linked to renal disease. However, little is known concerning international variation in the correlations with hyperglycaemia and standard CVD risk factors. METHODS: A cross-sectional comparison was made of prevalence rates and risk factor associations in two large studies of IDDM subjects: the Pittsburgh Epidemiology of Diabetes Complications Study (EDC) and the EURODIAB IDDM Complications Study from 31 centres in Europe. Subgroups of each were chosen to be comparable by age and duration of diabetes. The EDC population comprises 286 men (mean duration 20.1 years) and 281 women (mean duration 19.9 years); EURODIAB 608 men (mean duration 18.1 years) and 607 women (mean duration 18.9 years). The mean age of both populations was 28 years. Cardiovascular disease was defined by a past medical history of myocardial infarction, angina, and/or the Minnesota ECG codes (1.1-1.3, 4.1-4.3, 5.1-5.3, 7.1). RESULTS: Overall prevalence of CVD was similar in the two populations (i.e. men 8.6% versus 8.0%, women 7.4% versus 8.5%, EURODIAB versus EDC respectively), although EDC women had a higher prevalence of angina (3.9% versus 0.5%, P < 0.001). Multivariate modelling suggests that glycaemic control (HbA1c) is not related to CVD in men. Age and high density lipoprotein cholesterol predict CVD in EURODIAB, while triglycerides and hypertension predict CVD in EDC. For women in both populations, age and hypertension (or renal disease) are independent predictors. HbA1c is also an independent predictor-inversely in EURODIAB women (P < 0.008) and positively in EDC women (P = 0.03). Renal disease was more strongly linked to CVD in EDC than in EURODIAB. CONCLUSIONS: Despite a similar prevalence of CVD, risk factor associations appear to differ in the two study populations. Glycaemic control (HbA1c) does not show a consistent or strong relationship to CVD.  (+info)

TY - JOUR. T1 - A multicenter prospective cohort study to develop frailty-based prognostic criteria in heart failure patients (FLAGSHIP). T2 - Rationale and design. AU - on behalf of the FLAGSHIP collaborators. AU - Yamada, Sumio. AU - Adachi, Takuji. AU - Izawa, Hideo. AU - Izawa, Hideo. AU - Kondo, Takaaki. PY - 2018/8/2. Y1 - 2018/8/2. N2 - Background: Heart failure (HF) and frailty often co-exist, and frailty in HF results in a poor prognosis. However, in Asian populations, prognostic criteria are needed to examine the effect of frailty on HF. Therefore, we conducted a nationwide cohort study to develop frailty-based prognostic criteria in HF patients (FLAGSHIP). FLAGSHIP mainly aims to 1) develop the frailty criteria based on HF-specific outcomes, 2) propose a hypothesis of the potential mechanisms of frailty manifestations in HF, and 3) examine the effects of outpatient cardiac rehabilitation on frailty. Methods: In this prospective study, we consecutively enroll ambulatory patients ...
Observational Prospective Study to Evaluate AEs, Risk Factors and Drug Utilization of BUSCAPINA COMPOSITUM N in Adults From Metropolitan Lima
TY - THES. T1 - Respiratory pathogens and morbidity in the first year following very preterm birth: A 12-month prospective cohort study. AU - Townsi, Nada. PY - 2019. Y1 - 2019. N2 - This thesis prospectively characterises respiratory morbidity and respiratory pathogens in survivors of very preterm birth, less than 32 weeks gestation, for one year after hospital discharge using monthly respiratory questionnaire and parent-collected nasal swabs. Very preterm infants, irrespective of neonatal lung disease, experience a high burden of respiratory symptoms with 60.7% having recurrent wheeze (more than 3 episodes) during this time. Respiratory pathogens, most commonly rhinovirus, were readily detected during both symptomatic and asymptomatic assessments. Consequently, prescription of respiratory medications and healthcare utilisation were high. Further research is warranted to determine the long-term impacts of respiratory pathogens on respiratory health later in life. AB - This thesis prospectively ...
Pap screening, an effective method for cervical cancer prevention, is now supported by molecular human papillomavirus (HPV) testing. Recently commercialised preventive vaccines also provide new tools for the primary prevention of cervical cancer. To determine appropriate prevention strategies, the Health General Direction, Lombardy Region, funded a project that aims to characterize and monitor HPV infections and related cervical diseases in high-risk women.
Hayashi K, Milloy MJ, Wood E, Dong H, Montaner JS, Kerr T Predictors of liver-related death among people who inject drugs in Vancouver, Canada: a 15-year prospective cohort study Journal of the International AIDS Society PubMed. ...
A Prospective Observational Study on Pattern, Severity and Outcome of Different Poisoning Cases in a Tertiary Care Hospital, India, Vijay Mate
Out-of-hours care in the primary care setting is rapidly changing and evolving towards general practitioner cooperatives (GPC). GPCs already exist in the Netherlands, the United Kingdom and Scandinavia, all countries with strong general practice, including gatekeepers role. This intervention study reports the use and caseload of out-of-hours care before and after implementation of a GPC in a well subscribed region in a country with an open access health care system and no gatekeepers role for general practice. We used a prospective before/after interventional study design. The intervention was the implementation of a GPC. One year after the implementation of a GPC, the number of patient contacts in the intervention region significantly increased at the GPC (OR: 1.645; 95% CI: 1.439-1.880), while there were no significant changes in patient contacts at the Emergency Department (ED) or in other regions where a simultaneous registration was performed. Although home visits decreased in all general
Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Authors: Maria Pellise, Nicholas G Burgess, Nicholas Tutticci, Luke F Hourigan, Simon A Zanati, Gregor J Brown, Rajvinder Singh, Stephen J Williams, Spiro C Raftopoulos, Donald Ormonde, Alan Moss, Karen Byth, Heok PNg, Hema Mahajan, Duncan McLeod, Michael J Bourke
Background and purpose: About 20% of patients with acute ischemic stroke experience symptom progression resulting in poor outcome. We have evaluated the effect of cilostazol compared with aspirin on preventing acute symptom progression, and on clinical outcome.. Methods: A multi-center, open, randomized, prospective comparative study conducted from April 2009 to March 2011. Inclusion criteria: non-cardioembolic ischemic stroke admitted within 48 hours of onset, neurologically stable, and with written informed consent. Exclusion criteria: contraindicated or previous exposure to aspirin and/or cilostazol. Patients were administered either cilostazol 200 mg daily (group C) or aspirin 200 mg daily (group A) within 48 hours of onset. Primary endpoint: occurrence of acute symptom progression (ΔNIHSS ≥2) within 7 days. Secondary endpoints: 3-month outcome (mRS 0-2), occurrence of vascular events (ischemic stroke, brain hemorrhage, myocardial infarction), bleeding events, and other adverse events. ...
Methods Prospective data on 204 lactating mothers of a healthy term singleton infant (normal pregnancy, labor and delivery) on day 2 after delivery. Exclusion: preterm and postterm infants, maternal treatment with antidepressant, anticonvulsants, or magnesium sulfate, previous breast surgery, opiates for analgesia; infants with major congenital malformations, or neonatal complications. Anthropometrics included: inter-nipple distance, nipple length, and horizontal and vertical diameters; cup size (best fit to a lactation bras); infant goniomaxillary length/gonio-mandibular length (GMxL/GMnL) ratio and intercommissural distance. A latch score was performed after measurements. Data collected included gravidity, parity, gestational age, previous breast feeding experience, and early breast feeding (,2 hours after delivery). Backward stepwise regression analysis was used to study the combined effect of several independent variables upon latch score. ...
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), ...
Multigenic approaches have been demonstrated to be valid tools for identifying subjects at risk for complex traits, such as type 2 diabetes (17) and coronary artery disease (18). A similar strategy was used in the present study, hypothesizing that, in subjects with type 2 diabetes, an increasing number of proinflammatory alleles may confer a significant risk of developing ischemic stroke. We have previously demonstrated the utility of the Go-DARTS cohort to study the contribution of gene variations to cardiovascular risk in subjects with diabetes (14-16). To our knowledge, this is the first prospective study that attempts to look at the impact of the combined effect of multiple gene variations on incident stroke. It is also the first prospective study considering the combination of multiple inflammatory SNPs in diabetic individuals.. The decision to study the rs1800795, rs5498, rs5361, rs1024611, and rs679620 of the IL-6, MCP-1, ICAM-1, sel-E, and MMP-3 genes was based on the following criteria. ...
Objective-To examine the relation between resting heart rate and new major ischaemic heart disease events in middle aged men with and without pre-existing ischaemic heart disease. Design-Prospective study of a cohort of men with eight years follow up for cardiovascular morbidity and mortality for all men. Setting-General practices in 24 British...
Multiple sclerosis (MS) patients have been considered a higher-risk population for COVID-19 due to the high prevalence of disability and disease-modifying therapy use; however, there is little data identifying clinical characteristics of MS associated with worse COVID-19 outcomes. Therefore, we conducted a multicenter prospective cohort study looking at the outcomes of 40 MS patients with confirmed COVID-19. Severity of COVID-19 infection was based on hospital course, where a mild course was defined as the patient not requiring hospital admission, moderate severity was defined as the patient requiring hospital admission to the general floor, and most severe was defined as requiring intensive care unit admission and/or death. 19/40(47.5%) had mild courses, 15/40(37.5%) had moderate courses, and 6/40(15%) had severe courses. Patients with moderate and severe courses were significantly older than those with a mild course (57[50-63] years old and 66[58.8-69.5] years old vs 48[40-51.5] years old, P = ...
Tolerability of Shortened Infliximab Infusion in Scheduled Maintenance Therapy for IBD: a Prospective Multi-center European Cohort Study
To analyze the impact of multimorbidity (MM) on health care costs taking into account data heterogeneity. Data come from a multicenter prospective cohort study of 1,050 randomly selected primary care patients aged 65 to 85 years suffering from MM in Germany. MM was defined as co-occurrence of ≥3 conditions from a list of 29 chronic diseases. A conditional inference tree (CTREE) algorithm was used to detect the underlying structure and most influential variables on costs of inpatient care, outpatient care, medications as well as formal and informal nursing care. Irrespective of the number and combination of co-morbidities, a limited number of factors influential on costs were detected. Parkinsons disease (PD) and cardiac insufficiency (CI) were the most influential variables for total costs. Compared to patients not suffering from any of the two conditions, PD increases predicted mean total costs 3.5-fold to approximately € 11,000 per 6 months, and CI two-fold to approximately € 6,100. The high
Patients with chronic renal failure show a greater incidence of malignancies. We evaluated whether moderately impaired renal function at baseline influenced risk of all cancers during long-term follow in young persons. Our cohort included 33,346 subjects, aged 26-61 years at baseline, in a representative, population-based study enrolling subjects from 1974 to 1992. Median follow-up time was 28 years. Plasma creatinine was analyzed as a single measure at baseline. Incident cases of cancer were identified from the Swedish Cancer Registry. We studied 24,552 subjects from the cohort. To account for the unique sampling design, participants were divided by sex and age at baseline into 1,132 older men (age 60), 14,254 younger men (age 40-52), 7,498 older women (age 47-57) and 1,688 younger women (age 35-43). Glomerular filtration rate (GFR) was estimated using the CKD-EPI formula. Patients were classified as having either normal to mildly impaired kidney function (eGFR ≥ 60 mL/min/1.73 m2), or moderate
Supplementary MaterialsSupplementary materials 1 (DOCX 637 KB) 392_2019_1424_MOESM1_ESM. not analyzed. The medial and lateral plots and by the KolmogorovCSmirnov test. Normally and non-Gaussian distributed variables were reported as mean (SD) or median (interquartile range), respectively. All biomarker levels were log10 transformed and normalised to 1 1 SD increment. Normalised data were analysed using ANOVA and general linear models, and values were Bonferroni-corrected for multiple comparisons. Non-Gaussian data and categorical variables were analysed using non-parametric tests [MannCWhitney test, KruskalCWallis test and Spearman (value(%) and imply (SD) or median (Interquartile range) are reported. beliefs are quoted for the ANOVA/Kruskal Chi or Wallis squared exams for constant or categorical factors, respectively angiotensin 2 receptor blocker Relationship evaluation PENK was correlated to age group (rating of log natriuretic peptides (0.437, nonsignificant). Open up in another home window ...
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In the frame of multicenter research studies, biobanks ensure the harmonization and traceability of the prospective collection of quality samples. This is significant because pre-analytical variables must be carefully considered to guarantee the integrity of biomarkers to be tested and to avoid bias affecting the validity of the analytical results. According to a quality management system, biobanks contribute with documents and records; consumable preparation for collection, processing, and conservation; sample quality controls; and centralized management of sample handling, storage, and distribution. Traceability of samples is based on unique standard codes and the use of pre-assigned, pre-coded, and pre-labeled materials for sample collection, processing, and conservation. By using these supporting tools, quality derivatives are obtained based on common and evidence-based standard operating procedures (SOPs), with associated traceability information in relation with their collection, processing,
Langdorf MI, Medak AJ, Hendey GW, Nishijima DK, Mower WR, Raja AS, Baumann BM, Anglin DR, Anderson CL, Lotfipour S, Reed KE, Zuabi N, Khan NA, Bithell CA, Rowther AA, Villar J, Rodriguez RM. Prevalence and Clinical Import of Thoracic Injury Identified by Chest Computed Tomography but Not Chest Radiography in Blunt Trauma: Multicenter Prospective Cohort Study. Ann Emerg Med. 2015 Dec;66(6):589-600. doi: 10.1016/j.annemergmed.2015.06.003. Epub 2015 Jul 11. PubMed PMID: 26169926 ...
The goal of the initial 3-year effort of this overall project is to develop and test a framework for establishing a long-term fire fighter multicenter prospective cohort study focused on carcinogenic exposures and effects. This information is essential to guide interventions to reduce the most important carcinogenic exposures and develop treatment options to potentially reverse carcinogenic effects in their early stages. ...
OBJECTIVE--To examine the associations between air temperature and risk factors for ischaemic heart disease. METHOD--Data on risk factors are available from up to 2036 men in the Caerphilly Prospective Heart Disease Study. Daily temperatures were obtained from the Meteorological Office. Relations between these were examined by regression. RESULTS--The coldest month of the year has a mean temperature that is 16 degrees C lower than that in the warmest month. A fall in temperature of this magnitude is associated with higher blood pressures (by 3-5 mm Hg) and a lower concentration of high density lipoprotein cholesterol (by 0.08 mmol/l). The most important effects however, seem to be on the haemostatic system. Fibrinogen is 0.34 g/l higher in the coldest month than in the warmest (p , 0.001) and alpha 2 macroglobulin, a protein that inhibits fibrinolysis, is also raised. Platelet count is increased by 30% of a standard deviation and the sensitivity of platelets in whole blood to adenosine ...
The association between dietary Fe intake and diabetes risk remains inconsistent. We aimed to explore the association between dietary Fe intake and type 2 diabetes mellitus (T2DM) risk in middle-aged and older adults in urban China. This study used data from the Guangzhou Nutrition and Health Study, an on-going community-based prospective cohort study. Participants were recruited from 2008 to 2013 in Guangzhou community. A total of 2696 participants aged 40-75 years without T2DM at baseline were included in data analyses, with a median of 5·6 (interquartile range 4·1-5·9) years of follow-up. T2DM was identified by self-reported diagnosis, fasting glucose ≥ 7·0 mmol/l or glycosylated Hb ≥ 6·5 %. Cox proportional hazard models were used to estimate hazard ratios (HR) and 95 % CI. We ascertained 205 incident T2DM cases during 13 476 person-years. The adjusted HR for T2DM risk in the fourth quartile of haem Fe intake was 1·92 (95 % CI 1·07, 3·46; P trend = 0·010), compared with the ...
View Poster. INTRODUCTION. Multiple surgical techniques have been proposed for patients with clinically significant PD. The technique of grafting with hemostatic self-adhesive fleece of collagen-fibrinogen-thrombin has been popularized in Europe (single surgeon, single institution) with potential advantages (shorter surgery duration, less technically demanding procedure and relatively cheaper than other graft materials). However, there is no prospective or multicenter evidence to evaluate the outcomes of this technique. Our aim is to evaluate the preliminary outcomes in patients who underwent this technique in 11 Spanish centers after 16 months of recruiting.. METHODS. Between July 2016 and October 2017, 43 patients underwent surgery in 11 Spanish centers using the previously described technique. Preoperative, intraoperative and post-surgical data were collected prospectively and follow up at 3 and 6 months with questionnaires (PDQ, EHS, IIEF-5 and satisfaction) was performed. All patients ...
To determine the time course of development of resistance to atevirdine mesylate ( U-87201E ) in patients with HIV isolates showing in vitro resistance to zidovudine ( AZT ). To determine the genotype changes in HIV reverse transcriptase associated with in vitro AZT resistance to U-87201E. To determine the genotype and phenotype effects of treatment with a nondideoxynucleoside agent on the alterations of the HIV-1 population associated with in vitro AZT resistance. To determine whether serial passage of patient pre-drug HIV isolates in the presence of U-87201E will generate the resistant mutants that may subsequently emerge in the patients ...
This page contains the abstract Morbidity and Mortality of Major Adult Spinal Surgery. A Prospective Cohort Analysis of 942 Consecutive Patients http://www.chiro.org/LINKS/ABSTRACTS/Morbidity_and_Mortality_of_Major_Adult.shtml
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Nicotine dependence in a prospective population-based study of adolescents: the protective role of a functional tyrosine hydroxylase polymorphism Journal Articles Refereed ...
Prospective studies are key study designs when attempting to unravel health mechanisms that are widely applicable. Understanding the internal validity of a prospective study is essential to judge a studys quality. Moreover, insights in possible sampling bias and the external validity of a prospective study are useful to judge the applicability of a studys findings. We evaluated participation, retention, and associated factors of women in a multicenter prospective cohort (FemCure) to understand the studys validity.Chlamydia trachomatis (CT) infected adult women, negative for HIV, syphilis, and Neisseria gonorrhoeae were eligible to be preselected and included at three sexually transmitted infection (STI) clinics in the Netherlands (2016-2017). The planned follow-up for participants was 3 months, with two weekly rectal and vaginal CT self-sampling and online questionnaires administered at home and at the clinic. We calculated the proportions of preselected, included, and retained (completed ...
This study is the first to document the population incidence in the UK of SUPC in infants who were assessed as being healthy at birth. The incidence (0.05/1000 term live births) is consistent with case, regional and national series, suggesting an incidence ranging from between 0.026/1000 live births in the first 24 h of birth10 to 0.27/1000 where collapse occurs within 3 days of birth.2 The overall BPSU respondent rate (94.6% for 2008) is higher than any equivalent UK scheme and ranks highly against other national paediatric surveillance units. However, complete ascertainment of all cases of SUPC occurring within the study period could not be verified. This was due to the complexity of the case definition and the heterogeneity that exists in the classification of such infant deaths, which precluded cross-checking against national and regional databases. As such, the incidence in this study may be an underestimate.. One third of infants had an underlying condition leading to collapse and a ...
Background Multiple Sclerosis (MS) is the most common cause of neurological disability in young and middle-aged adults. At this stage in life most people are in the midst of their working career. The...
Context: Despite the frequent occurrence of depressive symptoms among older adults, especially women, little is known about the long-term course of late-life depressive symptoms. Objective: To characterize the natural course of depressive symptoms among older women (from the young old to the oldest old) followed up for almost 20 years. Design: Using latent-class growth-curve analysis, we analyzed women enrolled in an ongoing prospective cohort study (1988 through 2009). Setting: Clinic sites in Baltimore, Maryland; Minneapolis, Minnesota; the Monongahela Valley near Pittsburgh, Pennsylvania; and Portland, Oregon. Participants: We studied 7240 community-dwelling women 65 years or older. Main Outcome Measure: The Geriatric Depression Scale short form (score range, 0-15) was used to routinely assess depressive symptoms during the follow-up period. Results: Among older women, we identified 4 latent classes during 20 years, with the predicted probabilities of group membership totaling 27.8% with ...
Jeffrey Moses, MD, presents results from PROTECT III, the largest prospective study of Impella for high-risk PCI in the real world.
This study represents the largest prospective series of febrile children returning from the tropics. We have identified a high proportion of treatable conditions, and highlighted the importance of common cosmopolitan infections as well as exotic illnesses presenting with fever in this population. The majority of diagnoses requiring medical treatment were made using simple investigations.. Previous studies of imported infections have concentrated on adult travellers presenting to tertiary centres,6 often returning from Sub-Saharan Africa.4,5 Our study population, being largely South Asian, is therefore very different. Most imported malaria from the Indian subcontinent is caused by Plasmodium vivax, as in our study.9 Only 30% of children with this type of malaria present within a month of return.9 Imported malaria from Africa is mostly P falciparum, a potentially life threatening infection. This mostly presents within one month of return.9. Many new arrivals from Africa will stay in the South East ...
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The majority of youth with type 1 diabetes are above hemoglobin A1c (HbA1c) targets. Continuous glucose monitoring (CGM) has been shown to improve clinical outcomes, and use early in the course of diabetes has the potential to improve glycemic outcomes and improve quality of life.. In our clinic, youth with new-onset type 1 diabetes were offered the opportunity to start on CGM (Dexcom G6) soon after diabetes diagnosis. Ongoing CGM coverage was subsequently applied for through the patients insurance. Following CGM initiation, youth had a 1-week follow-up with a nurse practitioner. Per clinic standard of care, youth were seen again at 1 month post-diagnosis and every 3 months thereafter. We prospectively collected data on HbA1c, continued CGM use, days of CGM wear, method of viewing CGM data, time in range (TIR), and time in hypoglycemia. Institutional review board approval was obtained for the prospective data collection.. From July 2018 to April 2019, we approached 44 youth with newly diagnosed ...
Data presented as median (interquartile range). P value by Kruskall-Wallis. Intergroup differences by Mann Whitney. +P value significantly higher in fentanyl group compared to morphine group (p,0.05). N.S=Non Significant ...
Bernard Dubray, Muriel Garcia-Ramirez, Robert Apardian. [The case for a national prospective study on radiation therapy-induced lung toxicity]. Cancer Radiothérapie, Elsevier Masson, 2008, 12 (2), pp.134-5. ⟨10.1016/j.canrad.2007.11.009⟩. ⟨inserm-00467281⟩ ...
To our knowledge, this is the first prospective study in which BF and metabolism were measured in parallel using [15O]H2O and [18F]FDG PET/CT in patients presenting with suspicion of pancreatic cancer. We found average BF to be significantly decreased and metabolism significantly increased in malignant pancreatic lesions compared with normal pancreas. Based on our initial findings, we hypothesize that a high ratio of metabolism to BF may predict survival better than either functional measurement alone.. At a time when the possibilities and limitations (22) of new therapeutic agents targeting angiogenic mechanisms of tumors are being recognized, it is becoming obvious that careful classification and selection of patients prior to treatment is necessary for these therapeutic strategies to be successful. This is of particular importance in malignancies with a low likelihood of response, such as pancreatic cancer (6). In this respect, tumor perfusion and metabolism seem to be among the most relevant ...
De HvA inspireert studenten om met creatieve oplossingen en duurzame innovaties aan de toekomst te werken; om vandaag te verbinden met morgen.
Following this initial letter, two subsequent case series have been published supporting the peripheral-IJ as a reasonable alternative for temporary venous access. The first case series of 9 patients placed them in patients with unobtainable IV access [2]. 64 mm angiocatheters were used to cannulate the IJ under ultrasound guidance using the above-described technique. All catheters were labeled for removal within 72 hrs. All patients were followed up via chart review one year later. Two of 9 catheters failed due to kinking within the first 48 hrs. There were no apparent adverse outcomes in any patient including deep vein thrombosis, bacteremia, endocarditis or pneumothorax. A second group conducted a prospective case series in which 9 patients underwent placement of a peripheral IJ (PIJ), when other access could not be obtained and the patient did not initially require a central line [3]. The authors attempted follow-up with all patients within a week. On follow-up, the seven patients who ...
Use the SQL Server aggregate function IQR to calculate inter-quartile range. Documentation on over 260 SQL Server statistical functions including examples that can be copied directly into SSMS.
To characterize the PK of IgG following intravenous IgPro10 dosing in Japanese PID subjects after a standard wash-in/wash-out period of 12 weeks.
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OBJECTIVES--To assess the relationship between haematocrit and risk of major ischaemic heart disease events. DESIGN--Prospective study of a cohort of men followed up for 9.5 years. SETTING--General practices in 24 towns in England, Wales, and Scotland (British Regional Heart Study). SUBJECTS--Altogether 7735 men aged 40-59 years at screening, who were selected at random from one general practice in each of 24 towns, were studied. MAIN OUTCOME MEASURES--Fatal and nonfatal ischaemic heart disease events. RESULTS--Risk of major ischaemic heart disease events was significantly increased at haematocrit levels of , or = 46.0%. Men with raised haematocrit (, or = 46.0%) showed a 30% increase in relative risk (RR) of major ischaemic heart disease events (RR = 1.32; 95% confidence intervals (CI) 1.10,1.57, p , 0.01) compared with those with values below 46.0%, even after adjustment for age, social class, smoking, body mass index, physical activity, blood cholesterol, lung function (FEV1), and ...
TY - JOUR. T1 - Workplace social capital and the onset of major depressive episode among workers in Japan. T2 - A 3-year prospective cohort study. AU - Sakuraya, Asuka. AU - Imamura, Kotaro. AU - Inoue, Akiomi. AU - Tsutsumi, Akizumi. AU - Shimazu, Akihito. AU - Takahashi, Masaya. AU - Totsuzaki, Takafumi. AU - Kawakami, Norito. PY - 2017/6/1. Y1 - 2017/6/1. N2 - Background This study examined the prospective association of workplace social capital (WSC) with major depressive episode (MDE) among Japanese employees. Methods A 3-year prospective cohort study was conducted among 1058 employees from a private thinktank company who participated in a baseline survey; after excluding those with MDE in the past 12 months, 929 were followed up. WSC at baseline was measured using a 3-item scale. MDE was assessed at baseline and at follow-up every year, by using a web-based, selfadministered version of the WHO Composite International Diagnostic Interview (WHO-CIDI) 3.0 depression section, based on the ...
Fertility and pregnancy issues are of key importance for young breast cancer patients. Despite several advances in the field, there are still multiple unmet needs and barriers in discussing and dealing with these concerns. To address the significant challenges related to fertility and pregnancy issues, the PREgnancy and FERtility (PREFER) study was developed as a national comprehensive program aiming to optimize care and improve knowledge around these topics. The PREFER study is a prospective cohort study conducted across several Italian institution affiliated with the Gruppo Italiano Mammella (GIM) group evaluating patterns of care and clinical outcomes of young breast cancer patients dealing with fertility and pregnancy issues. It is composed of two distinctive studies: PREFER-FERTILITY and PREFER-PREGNANCY. The PREFER-FERTILITY study is enrolling premenopausal patients aged 18-45 years, diagnosed with non-metastatic breast cancer, who are candidates to (neo)adjuvant chemotherapy and not previously
Grieving relatives can suffer from numerous consequences like anxiety, depression, post-traumatic stress disorder (PTSD) symptoms, and prolonged grief. This study aims to assess the psychological consequences of grieving relatives after patients death in French palliative care units and their needs for support. This is a prospective observational multicenter mixed study. Relatives of adult patients with a neoplasia expected to be hospitalized more than 72 h in a palliative care unit for end-of-life issues will be included within 48 h after patient admission. End-of-life issues are defined by the physician at patient admission. Relatives who are not able to have a phone call at 6-months are excluded. The primary outcome is the incidence of prolonged grief reaction defined by an ICG (Inventory Complicate Grief) | 25 (0 best-76 worst) at 6 months after patient death. Prespecified secondary outcomes are the risk factors of prolonged grief, anxiety and depression symptoms between day 3 and day 5 and at 6
TY - JOUR. T1 - Predictive validity of weekly monitoring of wound status using DESIGN-R score change for pressure ulcer healing. T2 - A multicenter prospective cohort study. AU - Iizaka, Shinji. AU - Sanada, Hiromi. AU - Matsui, Yuko. AU - Furue, Masutaka. AU - Tachibana, Takao. AU - Nakayama, Takeo. AU - Sugama, Junko. AU - Furuta, Katsunori. AU - Tachi, Masahiro. AU - Tokunaga, Keiko. AU - Miyachi, Yoshiki. PY - 2012/7. Y1 - 2012/7. N2 - There are few studies on predictive validity of methods to monitor the healing process of pressure ulcers. We evaluated whether the change of DESIGN-R (rating) score could predict subsequent healing, and determined the optimal cutoff points. In a multicenter prospective cohort study, patients were followed until wound healing or censoring. Wound severity was evaluated by the DESIGN-R tool every week, and the score change was calculated over 1-4 weeks (n = 411, 286, 224, and 170, respectively). In the multivariate analyses stratified by depth, a one-point ...
Synergistic effects of Vitamin D and magnesium in non-specific low back ache (nLBA) - A prospective comparative study - IJOR- Print ISSN No: - 2581-8112 Online ISSN No:- 2581-9151 Article DOI No:- 10.18231/j.ijor.2021.007, IP International Journal of Orthopaedic Rheumatology-IP Int J Orthop Rheumatol
Objective: To report adverse events (AEs) seen in a large cohort of patients with Juvenile Idiopathic Arthritis (JIA) treated with TNFα blockers (Infliximab and Etanercept).. Methods: All JIA patients treated with Infliximab or Etanercepet at the Paediatric Rheumatologic Centre of the G. Pini Institute (Milan) from November 1999 to February 2006, were enrolled in an open, monocenter, long-term prospective study.. Results: 163 patients (68 Infliximab, 95 Etanercept) were enrolled. Mean onset age 6.4±4.8 years, mean age 17.19.2 years, mean therapy duration 22.9±17.6 months. 45 patients (32 Infliximab, 13 Etanercept) failed to respond to or did not tolerate the first biologic and switched to a second one. 208 treatments (81 Infliximab, 127 Etanercept) were done. 71 AEs occurred in 51 (62.9%) Infliximab patients and led to discontinuation in 26 (32.1%). 133 AEs occurred in 69 (54.3%) Etanercept patients and led to discontinuation in 18 (14.2%). Some AEs, such as thrombocytopenia, ...
TY - JOUR. T1 - A dose-response meta-analysis of the impact of body mass index on stroke and all-cause mortality in stroke patients. T2 - a paradox within a paradox. AU - Bagheri, M.. AU - Speakman, J. R.. AU - Shabbidar, S.. AU - Kazemi, F.. AU - Djafarian, K.. N1 - Acknowledgements We thank Dr. Nicola Orsini for helping us with the statistical analysis. This study was supported by Tehran University of Medical Sciences.. PY - 2015/5. Y1 - 2015/5. N2 - The obesity paradox is often attributed to fat acting as a buffer to protect individuals in fragile metabolic states. If this was the case, one would predict that the reverse epidemiology would be apparent across all causes of mortality including that of the particular disease state. We performed a dose-response meta-analysis to assess the impact of body mass index (BMI) on all-cause and stroke-specific mortality among stroke patients. Data from relevant studies were identified by systematically searching PubMed, OVID and Scopus databases and were ...
TY - JOUR. T1 - Re. T2 - the natural history of penile length after radical prostatectomy: a long-term prospective study.. AU - Morey, Allen F.. PY - 2013/8. Y1 - 2013/8. UR - http://www.scopus.com/inward/record.url?scp=84887337808&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84887337808&partnerID=8YFLogxK. M3 - Article. C2 - 23845350. AN - SCOPUS:84887337808. VL - 190. SP - 592. JO - Journal of Urology. JF - Journal of Urology. SN - 0022-5347. IS - 2. ER - ...
Jehan, I., Harris, H., Salat, S., Zeb, A., Mobeen, N., Pasha, O., ... Goldenberg, R. L. (2009). Neonatal mortality, risk factors and causes: A prospective population-based cohort study in urban Pakistan. Bulletin of the World Health Organization, 87(2), 130-138. DOI: 10.2471/BLT.08.050963 ...
OBJECTIVES: If proven acceptable, safe and effective, the diaphragm could be used as a female-controlled method of preventing both sexually-transmitted infections (STIs) and pregnancy. This studys aim was to assess the acceptability and safety of the diaphragm among sexually-active women in Mombasa, Kenya. METHODS: We conducted a 6-month prospective study among female sex workers (FSWs), and women attending sexual and reproductive health services. Diaphragm acceptability was assessed using continuation rates and factors associated with acceptability. Safety evaluations included colposcopy findings and incidence of urinary tract infections (UTIs) and STIs. RESULTS: Half the 185 participants were FSWs who had less schooling and were less likely to be married than other women. After 6 months, 55% (56/102) of sexually-active women reported having used the diaphragm each sex act during the preceding month. Women liked using the diaphragm (95%, 104/109), and 96% (125/130) reported willingness to ...
TY - JOUR. T1 - Risk factors of nonunion after acute osteoporotic vertebral fractures. T2 - A prospective multicenter cohort study. AU - Inose, Hiroyuki. AU - Kato, Tsuyoshi. AU - Ichimura, Shoichi. AU - Nakamura, Hiroaki. AU - Hoshino, Masatoshi. AU - Togawa, Daisuke. AU - Hirano, Toru. AU - Tokuhashi, Yasuaki. AU - Ohba, Tetsuro. AU - Haro, Hirotaka. AU - Tsuji, Takashi. AU - Sato, Kimiaki. AU - Sasao, Yutaka. AU - Takahata, Masahiko. AU - Otani, Koji. AU - Momoshima, Suketaka. AU - Yuasa, Masato. AU - Hirai, Takashi. AU - Yoshii, Toshitaka. AU - Okawa, Atsushi. N1 - Funding Information: Acknowledgment date: August 30, 2019. First revision date: October 6, 2019. Second revision date: November 13, 2019. Acceptance date: December 16, 2019. This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be ...
BÜHLMANN fCAL® ELISA Citation: Beswick, L. et al. Exploration of predictive biomarkers of early infliximab response in acute severe colitis: A prospective pilot study. Journal of Crohns and Colitis. 2017 Nov 7. DOI: 10.1093/ecco-jcc/jjx146. PMID: 29121178 . Highlight from this Publication
TY - JOUR. T1 - Erratum. T2 - A prospective study evaluating the accuracy of using combined clinical factors and candidate diagnostic markers to refine the accuracy of thyroid fine needle aspiration biopsy (Surgery (2010) 148:6 (1170-1177)). AU - Mathur, Aarti. AU - Weng, Julie. AU - Moses, Willieford. AU - Steinberg, Seth M.. AU - Rahabari, Reza. AU - Kitano, Mio. AU - Khanafshar, Elham. AU - Ljung, Britt Marie. AU - Duh, Quan Yang. AU - Clark, Orlo H.. AU - Kebebew, Electron. PY - 2012/2/1. Y1 - 2012/2/1. UR - http://www.scopus.com/inward/record.url?scp=84855798443&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84855798443&partnerID=8YFLogxK. U2 - 10.1016/j.surg.2011.12.039. DO - 10.1016/j.surg.2011.12.039. M3 - Comment/debate. AN - SCOPUS:84855798443. VL - 151. JO - Surgery. JF - Surgery. SN - 0039-6060. IS - 2. ER - ...
Clinical trial for Mother to Child Transmission of HIV , Prospective Observational Cohort Study on Mother to Child Transmission HIV1/HIV2 and Prevention
TY - JOUR. T1 - Treatment- and cost-effectiveness of early intervention for acute low-back pain patients. T2 - A one-year prospective study. AU - Gatchel, Robert J.. AU - Polatin, Peter B.. AU - Noe, Carl. AU - Gardea, Margaret. AU - Pulliam, Carla. AU - Thompson, Judy. N1 - Funding Information: The authors thank Dr Michael Kashner for his help in conducting the cost-comparison data analyses. This research work has been supported in part by Grant 2R01-MH46452 and 2K02-MH01107 awarded by the National Institute of Mental Health.. PY - 2003/3. Y1 - 2003/3. N2 - In an attempt to prevent acute low-back pain from becoming a chronic disability problem, an earlier study developed a statistical algorithm which accurately identified those acute low-back pain patients who were at high risk for developing such chronicity. The major goal of the present study was to evaluate the clinical effectiveness of employing an early intervention program with these high-risk patients in order to prevent the development ...
Objective To independently evaluate the performance of the QRISK score for predicting 10 year risk of cardiovascular disease in an independent UK cohort of patients from general practice and compare the performance with Framingham equations.. Design Prospective open cohort study.. Setting 274 practices from England and Wales contributing to the THIN database.. Participants 1.07 million patients, registered between 1 January 1995 and 1 April 2006, aged 35-74 years (5.4 million person years) with 43 990 cardiovascular events.. Main outcome measures First diagnosis of cardiovascular disease (myocardial infarction, coronary heart disease, stroke, and transient ischaemic attack) recorded in general practice records.. Results This independent validation indicated that QRISK offers an improved performance in predicting the 10 year risk of cardiovascular disease in a large cohort of UK patients over the Anderson Framingham equation. Discrimination and calibration statistics were better with QRISK. QRISK ...
In 1986 a prospective cohort study on diet and cancer was started in the Netherlands among 62,573 women ages 55-69 years. Baseline information on diet and other risk factors was collected with a questionnaire. Cancer incidence was measured by record linkage with cancer registries and a pathology register. A case-cohort approach was used, in which the accumulated person time in the cohort was estimated by follow-up of a randomly selected subcohort (n = 1812). After 3.3 years of follow-up, 471 incident breast cancer cases were available for analysis. Questionnaire data for these cases and the 1716 female subcohort members without a history of cancer other than skin cancer were analyzed. In a multivariate analysis, controlling for traditional risk factors, the relative rates for breast cancer in increasing quintiles of energy-adjusted total fat intake were 1.00, 1.00, 1.34, 1.22, 1.08 (P-trend, 0.32). For saturated fat there was some evidence for a weak positive association when quintiles were used ...
TY - JOUR. T1 - Early cardiac changes following anthracycline chemotherapy in breast cancer: a prospective multi-centre study using advanced cardiac imaging and biochemical markers. AU - Grover, Suchi. AU - De Pasquale, Carmine. AU - Leong, Darryl. AU - Chakrabarty, Adhiraj. AU - Cheong, Kerry. AU - Kotasek, Dusan. AU - Joshi, Rohit. AU - Penhall, Amy. AU - Joerg, Lucas. AU - Joseph, Majo. AU - Koczwara, Bogda. AU - Selvanayagam, Joseph. PY - 2012. Y1 - 2012. M3 - Article. VL - 14. SP - 181. EP - 182. JO - Journal of Cardiovascular Magnetic Resonance. JF - Journal of Cardiovascular Magnetic Resonance. SN - 1097-6647. IS - S1. ER - ...
Atrial fibrillation (AF) after thoracic surgery is a continuing source of morbidity and mortality. The effect of postoperative AF on long-term survival however has not been studied. Our aim was to evaluate the impact of AF on early outcome and on survival | 5 years after pulmonary lobectomy for lung cancer. From 1996 to June 2009, 454 consecutive patients undergoing lobectomy for lung cancer were enrolled and followed-up until death or study end (October 2010). Patients with postoperative AF were identified; AF was investigated with reference to its predictors and to short- and long-term survival (| 5 years). Hospital mortality accounted for 7 patients (1.5%), while postoperative AF occurred in 45 (9.9%). Independent AF predictors were: preoperative paroxysmal AF (odds ratio [OR] 5.91; 95%CI 2.07 to 16.88), postoperative blood transfusion (OR 3.61; 95%CI 1.67 to 7.82) and postoperative fibro-bronchoscopy (OR 3.39; 95%CI 1.48 to 7.79). Patients with AF experienced higher hospital mortality (6.7% vs. 1.0%
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IMPORTANCE: Muscle pain, fatigue, and weakness are common adverse effects of statin medications and may decrease physical activity in older men. OBJECTIVE: Determine whether statin use is associated with physical activity, longitudinally and cross-sectionally. DESIGN, SETTING, AND PARTICIPANTS: Men participating in the Osteoporotic Fractures in Men Study, a multicenter prospective cohort study of community-living men age 65+, enrolled between March 2000-April 2002. EXPOSURE: Statin use as determined by an inventory of medications (taken within last 30 days). In cross-sectional analyses, statin use categories were: users and nonusers. In longitudinal analyses, categories were: prevalent users (baseline use and throughout study), new users (initiated use during the study) and nonusers (never used). MAIN OUTCOMES AND MEASURE: Self-reported physical activity at baseline and 2 follow-up visits using the Physical Activity Scale for the Elderly (PASE). At the third visit, an accelerometer measured ...
TY - JOUR. T1 - Association between dietary whole grain intake and risk of mortality. T2 - Two large prospective studies in US Men and Women. AU - Wu, Hongyu. AU - Flint, Alan J.. AU - Qi, Qibin. AU - Van Dam, Rob M.. AU - Sampson, Laura A.. AU - Rimm, Eric B.. AU - Holmes, Michelle D.. AU - Willett, Walter C.. AU - Hu, Frank B.. AU - Sun, Qi. PY - 2015/3/1. Y1 - 2015/3/1. N2 - IMPORTANCE: Higher intake of whole grains has been associated with a lower risk of major chronic diseases, such as type 2 diabetes mellitus and cardiovascular disease (CVD), although limited prospective evidence exists regarding whole grains association with mortality. OBJECTIVE: To examine the association between dietary whole grain consumption and risk of mortality. DESIGN, SETTING, AND PARTICIPANTS: We investigated74 341 women from the Nurses Health Study (1984-2010) and 43 744 men from the Health Professionals Follow-Up Study (1986-2010), 2 large prospective cohort studies. All patients were free of CVD and cancer ...
OBJECTIVE To investigate the association of vitamin D status with all-cause mortality in a Norwegian population and the potential influences of existing chronic diseases on the association. DESIGN A population-based prospective cohort study. SETTING Nord-Trøndelag County, Norway. PARTICIPANTS A random sample (n=6613) of adults aged 20 years or older in a cohort. METHODS Serum 25-hydroxyvitamin D (25(OH)D) levels were measured in blood samples collected at baseline (n=6377). Mortality was ascertained from the Norwegian National Registry. Cox regression models were applied to estimate the HRs with 95% CIs for all-cause mortality in association with serum 25(OH)D levels after adjustment for a wide spectrum of confounding factors as well as chronic diseases at baseline. RESULTS The median follow-up time was 18.5 years, during which 1539 subjects died. The HRs for all-cause mortality associated with the first quartile level of 25(OH)D (|34.5 nmol/L) as compared with the fourth quartile (≥58.1
Drug utilization evaluation (DUE) is an effective program to identify variability in drug use and to support interventions that will improve patient outcomes. The appropriate use of enoxaparin, a low molecular weight heparin (LMWH), which is widely used as curative or preventive treatment of thromboembolic disorders was assessed in the study. A prospective DUE was carried out at Masih Daneshvari teaching hospital. Criteria for the appropriate use of enoxaparin was used to evaluate prescription and administration patterns in this hospital. Enoxaparin utilization of 147 inpatients was reviewed. A total of 944 variables (70.92%) in the regimen, among all subjects, were rated as appropriate and 382 (28.70%) were rated as inappropriate for the conditions diagnosed. The results of this study showed that inappropriate dosing, administration and prescribing of enoxaparin is rather common in masih hospital. Educational programs and implementation of protocols may be needed in the teaching hospitals to control
Objective. To assess the outcome and adverse prognostic factors of bacterial arthritis BA. Methods. In a prospective community survey of BA, data were collected at the time of diagnosis and at a mean of 2 years later. A poor patient outcome was defined as death due to BA or severe overall functional deterioration. A poor joint outcome was...
TY - JOUR. T1 - Extended infusion of β-lactams for bloodstream infection in patients with liver cirrhosis: An observational multicenter study. AU - Bartoletti, M.. AU - Giannella, M.. AU - Lewis, R.E.. AU - Caraceni, P.. AU - Tedeschi, S.. AU - Paul, M.. AU - Schramm, C.. AU - Bruns, T.. AU - Merli, M.. AU - Cobos-Trigueros, N.. AU - Seminari, E.. AU - Retamar, P.. AU - Muñoz, P.. AU - Tumbarello, M.. AU - Burra, P.. AU - Cerenzia, M.T.. AU - Barsic, B.. AU - Calbo, E.. AU - Maraolo, A.E.. AU - Petrosillo, N.. AU - Galan-Ladero, M.A.. AU - DOffizi, G.. AU - Zak-Doron, Y.. AU - Rodriguez-Baño, J.. AU - Baldassarre, M.. AU - Verucchi, G.. AU - Domenicali, M.. AU - Bernardi, M.. AU - Viale, P.. AU - group, ESGBIS/BICHROME study. N1 - Cited By :2 Export Date: 4 February 2020. PY - 2019. Y1 - 2019. U2 - 10.1093/cid/ciz032. DO - 10.1093/cid/ciz032. M3 - Article. VL - 69. SP - 1731. EP - 1739. JO - Clinical Infectious Diseases. JF - Clinical Infectious Diseases. SN - 1058-4838. IS - 10. ER - ...
© 2016 The Authors Introduction Wide local excision and adjuvant radiotherapy is the standard of care for early breast cancer. For large tumours, however, mastectomy is frequently recommended as conventional breast-conserving techniques often result in poor cosmetic outcomes. Therapeutic mammaplasty (TM) may extend the boundaries of breast-conserving surgery by combining breast reduction and mastopexy techniques with tumour excision, preserving a natural breast shape and avoiding the need for mastectomy. The prevalence of this operative option among surgeons in the UK and its success rate are unknown. The TeaM study is a multicentre prospective study that aims to investigate the practice and outcomes of TM. Methods and analysis Breast centres performing TM will be invited to participate through the research collaborative network and the professional associations. All patients undergoing TM between September 2016 and March 2017 will be included. Demographic, operative, oncological and complication data
This trial will compare the efficacy and tolerability of antithymocyte globulin [Thymoglobulin, rabbit antithymocyte globulin], mycophenolate mofetil
Results: In a cohort of 664 patients (median [interquartile range] observations: 3 [1 to 6]; data missing: BMI 2.5%, nutritional status 3.8%), BMI significantly increased from median [interquartile range] 24.4kg/m² [21.6kg/m² to 28kg/m²] in 2004 to 29.5kg/m² [24.4kg/m² to 35.4kg/m²] in 2019 (p,0.001). BMI categories significantly differed throughout the study period, with a decrease in underweight patients (31.6% to 18.1%), normal weight patients (26.7% to 16.3%) and overweight patients (20.2% to 18.6%); and increase in obese patients (21.5% to 47%) (χ² 142.9, df=12, p,0.001). The proportion of malnourished patients significantly decreased over time, from 14.5% to 9.3% (χ² 12.3, df=4, p=0.015 ...
TY - JOUR. T1 - The 2009 prospective multi-center epidemiologic survey of uveitis in Japan. AU - Ohguro, Nobuyuki. AU - Sonoda, Koh Hei. AU - Takeuchi, Masaru. AU - Matsumura, Miyo. AU - Mochizuki, Manabu. PY - 2012/9/1. Y1 - 2012/9/1. N2 - Purpose To investigate etiologic data on intraocular inflammation in Japan collected in the 2009 epidemiologic survey of uveitis in Japan and assess the current state of etiology compared with that reported in a previous survey. Methods Thirty-six university hospitals participated in this prospective etiologic study. Patients who visited the outpatient uveitis clinic of each hospital for the first time between 1 June 2009 and 31 May 2010 were enrolled in the study. Uveitic diseases were diagnosed according to the guidelines when available or following commonly accepted diagnostic criteria. Results A total of 3,830 patients were enrolled in the survey and 2,556 cases of uveitis were identified, of which 1,274 cases were described as unclassified intraocular ...
BACKGROUND: Chronic, low-grade inflammation is an established risk factor for cardiovascular disease. The inflammatory impact of diet can be reflected by concentrations of inflammatory markers in the bloodstream and the inflammatory potential of diet can be estimated by the dietary inflammatory index (DII(TM)), which has been associated with cardiovascular disease risk in some previous studies. We aimed to examine the association between the DII and the risk of first myocardial infarction (MI) in a population-based study with long follow-up.. METHOD: We conducted a prospective case-control study of 1389 verified cases of first MI and 5555 matched controls nested within the population-based cohorts of the Northern Sweden Health and Disease Study (NSHDS), of which the largest is the ongoing Västerbotten Intervention Programme (VIP) with nearly 100 000 participants during the study period. Median follow-up from recruitment to MI diagnosis was 6.4 years (6.2 for men and 7.2 for women). DII scores ...
Although neck pain is common in young adulthood, studies on predictive factors for its onset and persistence are scarce. It is therefore important to identify possible risk factors among young adults so as to prevent the development of neck pain later in life. A prospective study was carried out in healthy undergraduate students. At baseline, a self-administered questionnaire and standardized physical examination were used to collect data on biopsychosocial factors. At 3, 6, 9, and 12 months thereafter, follow-up data were collected on the incidence of neck pain. Those who reported neck pain on ≥ 2 consecutive follow-ups were categorized as having persistent neck pain. Two regression models were built to analyze risk factors for the onset and persistence of neck pain. Among the recruited sample of 684 students, 46% reported the onset of neck pain between baseline and 1-year follow-up, of whom 33% reported persistent neck pain. The onset of neck pain was associated with computer screen position not
These results suggest that bupropion does not increase the rates of major malformation above baseline. The higher rates of spontaneous abortions are similar to other studies examining the safety of antidepressants during pregnancy.
RESULTS: By age 4 years, the cumulative incidence of stuttering onset was 11.2% (95% confidence interval [CI]: 9.7% to 12.8%). Higher maternal education (P = .004), male gender (P = .02), and twinning (P = .005) predicted stuttering onset. At outcome, stuttering children had stronger language (mean [SD]: 105.0 [13.0] vs 99.6 [14.6]; mean difference 5.5, 95% CI: 3.1 to 7.8; P , .001) and nonverbal cognition (mean [SD]: 106.5 [11.4] vs 103.9 [13.7], mean difference 2.6, 95% CI: 0.4 to 4.8; P = .02) and better health-related quality of life but were otherwise similar to their nonstuttering peers. Only 9 of 142 children (6.3%; 95% CI: 2.9% to 11.7%) recovered within 12 months of onset. ...
Rheumatoid arthritis (RA) is a progressive disease, often leading to disability. Because the disease course develops rapidly during the first years after diagnosis, more knowledge is needed about the early disease course to minimize later disability. This thesis describes the course of disability in early RA such as hand function, pain intensity, activity limitation and sick leave. In addition, this thesis compares disability between women and men and compares disability between RA patients and referents.. This thesis is primarily based on data from the 320 patients that were included in the multi-centre project in Sweden called Early interventions in rheumatoid arthritis (TIRA). A wide range of outcome variables was registered between 1996 and 2006 during regular follow-ups from time for diagnosis through the eight-year follow-up. Outcome regarding disease activity and disability of RA patients still remaining in TIRA at the three and five year follow-up respectively are used in this thesis. ...
As part of a project to examine health care ethics consultation in Canada, we surveyed individuals who were considered by themselves or others to play a significant role in health care ethics consultation. Since one goal ...
Risikoforebygging er en viktig del av alt helsearbeid, men det meste av evidens med hensyn på forebyggende helsearbeid er fremkommet ved studier utført på middelaldrende befolkningsgrupper med ulik ekstern validitet, med variabel oppfølgingstid, og med overvekt av menn. Modifiserbare risikofaktorer har potensielt ulik innvirkning i ulike aldersgrupper, i ulike faser av en lengre oppfølgingstid og med hensyn på forskjellige endepunkter (dødelighet: total og årsaksspesifikk). Målsetning: å studere forskjeller og likheter i effekten av livsstilsrelaterte risikofaktorer (særlig kroppsmasseindeks, fysisk aktivitet og lungefunksjon) på total dødelighet og årsaksspesifikk dødelighet som følge av hjerneslag og koronar hjertesykdom i ulike aldersgrupper av menn og kvinner i en generell norsk befolkning med 42 års oppfølgingstid. Materiale og metode: 6811 tilfeldig utvalgte menn og kvinner i alderen 20-79 og bosatt i Bergen i 1964 ble invitert til en utvidet helseundersøkelse etter ...
Background: Prospective cohorts have suggested that physical activity (PA) can decrease the risk of incident anxiety. However, no meta-analysis has been conducted. Aims: To examine the prospective relationship between PA and incident anxiety and explore potential moderators. Methods: Searches were conducted on major databases from inception to October 10, 2018 for prospective studies (at least 1 year of follow-up) that calculated the odds ratio (OR) of incident anxiety in people with high PA against people with low PA. Methodological quality was assessed using the Newcastle-Ottawa Scale (NOS). A random-effects meta-analysis was conducted and heterogeneity was explored using subgroup and meta-regression analysis. Results: Across 14 cohorts of 13 unique prospective studies (N = 75,831, median males = 50.1%) followed for 357,424 person-years, people with high self-reported PA (versus low PA) were at reduced odds of developing anxiety (adjusted odds ratio [AOR] = 0.74; 95% confidence level [95% CI] ...
BA had a poor outcome in almost one-half of the patients. Patients who were older, had a preexisting joint disease, and/or had an infected joint containing synthetic material had the poorest prognosis.
Background: Large prospective epidemiologic studies are vital in determining disease etiology and forming national health policy. Yet, such studies do not exist in sub-Saharan Africa (SSA) notwithstanding the growing burden of chronic diseases. Objective: We explored the feasibility of establishing a large-scale multicountry prospective study at five sites in four sub-Saharan countries. Design: Based on country-specific considerations of feasibility, Nigeria enrolled health care professionals, South Africa and Tanzania enrolled teachers, and Uganda enrolled village residents at one rural and one periurban site each. All sites used a 6-month follow-up period but different approaches for data collection, namely standardized questionnaires filled out by participants or face-to-face interviews. Results: We enrolled 1415 participants from five sites (range 200489) with a median age of 41 years. Approximately half had access to clean-burning cooking fuel and 70% to piped drinking water, yet 92% had ...
Purpose: : To study the natural history and the major risk factors of ROP among the infants in Taiwan. Methods: : A prospective natural history study of ROP was performed for all premature infants from June 2010 to July 2011 at our childrens hospital. Patients were screened with birth weight (BW) less than 1500 grams or gestational age (GA) less than 32 weeks or selected infants with BW more than 1500 grams or GA more than 32 weeks with an unstable clinical course, including those requiring cardiorespiratory support and who are believed to be high risk by their pediatrician. The incidence of advanced ROP, the need for laser, Bevacizumab, or vitrectomy treatment was documented. The associated risk factors for the development of ROP were recorded. Results: : We enrolled 223 premature infants, and 98 infants (44%) developed ROP. The mean gestational age (GA) was 29.2 ± 3.0 (range 28-36) weeks and the mean BW was 1247.0 ± 441.5 (range 700-2705) grams. The incidence of ROP among BW more and less ...
Background: Physical activity (PA) is considered a cornerstone of diabetes mellitus management to prevent complications, but conclusive evidence is lacking. Methods: This prospective cohort study and meta-analysis of existing studies investigated the association between PA and mortality in individuals with diabetes. In the EPIC study (European Prospective Investigation Into Cancer and Nutrition), a cohort was defined of 5859 individuals with diabetes at baseline. Associations of leisure-time and total PA and walking with cardiovascular disease (CVD) and total mortality were studied using multivariable Cox proportional hazards regression models. Fixed-and random-effects meta-analyses of prospective studies published up to December 2010 were pooled with inverse variance weighting. Results: In the prospective analysis, total PA was associated with lower risk of CVD and total mortality. Compared with physically inactive persons, the lowest mortality risk was observed in moderately active persons: ...
Welcome to The Academy of Medical Cannabis - the globally leading institute for clinical training and research in cannabis-based medicinal products.
Evidence indicates that gaining weight in adult life is associated with an elevated risk of colorectal cancer; however, biological mechanisms that may explain this association remain unclear. We evaluated the mediation effect of 20 different biomarkers on the relationship between adult weight gain and colorectal cancer, using data from a prospective nested case-control study of 452 incident cases diagnosed between 1992 and 2003 and matched within risk sets to 452 controls within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The proportions of mediated effects (%) were estimated on the basis of differences in percent effect changes in conditional logistic regression models with and without additional adjustment for individual biomarkers. Greater adult weight gain (≥300 g/year vs. ,300 g/year) was associated with a higher risk of colon cancer (multivariable-adjusted relative risk = 1.54, 95% confidence interval: 1.07, 2.24) but not rectal cancer (relative risk = ...
Evidence indicates that gaining weight in adult life is associated with an elevated risk of colorectal cancer; however, biological mechanisms that may explain this association remain unclear. We evaluated the mediation effect of 20 different biomarkers on the relationship between adult weight gain and colorectal cancer, using data from a prospective nested case-control study of 452 incident cases diagnosed between 1992 and 2003 and matched within risk sets to 452 controls within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The proportions of mediated effects (%) were estimated on the basis of differences in percent effect changes in conditional logistic regression models with and without additional adjustment for individual biomarkers. Greater adult weight gain (≥300 g/year vs. ,300 g/year) was associated with a higher risk of colon cancer (multivariable-adjusted relative risk = 1.54, 95% confidence interval: 1.07, 2.24) but not rectal cancer (relative risk = ...
BACKGROUND AND PURPOSE: The impact of smoking on prognosis after stroke is controversial. We aimed to assess the relationship between smoking status and stroke outcome after intravenous thrombolysis in a large cohort study by adjusting for potential confounders and incorporating recanalization rates. METHODS: In a prospective observational multicenter study, we analyzed baseline and outcome data of consecutive patients with acute ischemic stroke treated with intravenous thrombolysis. Using uni- and multivariable modeling, we assessed whether smoking was associated with favorable outcome (modified Rankin Scale score of 0-1) and mortality. In addition, we also measured the occurrence of symptomatic intracranial hemorrhage and recanalization of middle cerebral artery. Patients reporting active cigarette use were classified as smokers. RESULTS: Of 1865 patients, 19.8% were smokers (n=369). They were younger (mean 63.5 versus 71.3 years), less often women (56% versus 72.1%), and suffered less often ...
Field Use and Prospective Studies[edit]. Despite the medical advances of detection, diagnosis and treatment methods throughout ... According to the American Journal of Respiratory and Critical Care Medicine, a prospectivestudy was conducted to determine the ... A Prospective Study". American Journal of Respiratory and Critical Care Medicine. 174: 982-989. doi:10.1164/rccm.200603-344oc. ... The overall diagnostic yield found in the present study is superior to rates reported in most previous studies performed for ...
Meta-analysis of prospective studies". Circulation. 102 (10): 1082-85. doi:10.1161/01.CIR.102.10.1082. PMID 10973834. Archived ... systematic review and dose-response meta-analysis of prospective cohort studies". BMJ (Clinical Research Ed.). 349: g4490. doi: ... meta-analysis of 141 cohort studies in 55 study reports". BMJ. 360: j5855. doi:10.1136/bmj.j5855. PMC 5781309 . PMID 29367388. ... The Stockholm Female Coronary Angiography Study". J. Intern. Med. 261 (3): 245-54. doi:10.1111/j.1365-2796.2006.01759.x. PMID ...
Systematic review of prospective cohort studies". BMJ (Clinical research ed.). 318 (7196): 1460-67. doi:10.1136/bmj.318.7196. ... Based on comparative studies, Marmot argues that we can make our society more participatory and inclusive to increase overall ... "Intersalt: An international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium ... He leads the English Longitudinal Study of Ageing (ELSA), and is engaged in several international research efforts on the ...
A prospective study". J Reprod Med. 27 (6): 321-7. PMID 7120209.. ... "Studies in Family Planning. 45 (3): 301-14. doi:10.1111/j.1728-4465.2014.00393.x. PMC 4727534 . PMID 25207494.. ... Shehan, Constance L. (2016). The Wiley Blackwell Encyclopedia of Family Studies, 4 Volume Set. John Wiley & Sons. p. 406. ISBN ... A study of singleton live births came to the result that childbirth has a standard deviation of 14 days when gestational age is ...
A prospective study". The American Journal of Sports Medicine. 31 (4): 585-89. doi:10.1177/03635465030310041801. PMID 12860549. ...
A prospective study". Am J Sports Med. 31 (4): 585-589. PMID 12860549.. ... Imaging studies, such as ultrasound or MRI, may reveal anatomic abnormalities or masses responsible for the impingement. ...
A prospective study". Danish Medical Bulletin.. *^ Feinfeld DA, Bargouthi H, Niaz Q, Carvounis CP (2002). "Massive and ...
Prospective studies collaboration». Lancet, 346, 8991-8992, 1995, pàg. 1647-53. DOI: 10.1016/S0140-6736(95)92836-7. PMID: ... UK Prospective Diabetes Study (UKPDS) Group». Lancet, 352, 9131, 1998, pàg. 837-53. DOI: 10.1016/S0140-6736(98)07019-6. PMID: ... Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone ... The Framingham Study». Arch. Intern. Med., 147, 9, 1987, pàg. 1561-4. DOI: 10.1001/archinte.147.9.1561. PMID: 3632164. ...
Retrospective and prospective studies. Acta Paediatrica Scandinavica Suppl. 1979, 275: 112-21. PMID 291283.. ... Goddard, H.H. (1912). The Kallikak Family: A Study in the Heredity of Feeble-Mindedness. New York: Macmillan. ... Committee to Study Fetal Alcohol Syndrome, Division of Biobehavioral Sciences and Mental Disorders, Institute of Medicine. ... Strömland K, Pinazo-Durán M. Ophthalmic involvement in the fetal alcohol syndrome: clinical and animal model studies. Alcohol ...
The last active longitudinal prospective study ended in 2000 with the end of the 36-year Denver study following the death of ... In prospective studies of 47,XYY boys identified by newborn screening programs, the IQ scores of 47,XYY boys were usually ... Prospective studies on children with sex chromosome aneuploidy. Birth defects original article series 22 (3). New York: Alan R ... In a summary of six prospective studies of 47,XYY boys identified by newborn screening programmes, twenty-eight 47,XYY boys had ...
Results of a prospective study". Ophthalmology. 98 (7): 1139-42. doi:10.1016/s0161-6420(91)32165-1. PMID 1891225.. ... Fluorescein has often been used to track water movement in groundwater to study water flow and observe areas of contamination ... In plant science, fluorescein, and other fluorescent dyes, have been used to monitor and study plant vasculature, particularly ... The higher rates may reflect study populations that include a higher percentage of persons with prior adverse reactions. The ...
A multi-centre prospective study". Thromb. Haemost. 95 (6): 949-57. doi:10.1160/TH06-02-0108. PMID 16732373.. ... early permanent study drug discontinuation, and end-of-study transition to open-label therapy. / In atrial fibrillation ... was not mandated by the study protocol during either temporary interruptions or at the end of the study. The bleeding rates ... The authors'... most likely explanation for the observed risk in the post-study transition period is not that rivaroxaban has ...
These studies were widely criticized as showing correlation, not causality. Followup prospective cohort studies in the early ... Followup large prospective cohort studies in the early 1950s showed clearly that smokers died faster, and were more likely to ... In a prospective study of community-dwelling people 60-90 years of age, during 1993, of unimmunized people 23% of smokers had ... Case-control studies were published in Germany in 1939 and 1943, and one in the Netherlands in 1948. A case-control study on ...
"U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective ... Studies have shown that it is possible to regenerate beta cells in vivo in some animal models.[33] Research in mice has shown ... A theoretical study". Biophysical Journal. 56 (2): 229-42. Bibcode:1989BpJ....56..229K. doi:10.1016/S0006-3495(89)82669-4. PMC ... Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)". ...
The prospective P2C2 HIV multicenter study. Circulation 1998;97:1246-56. Lewis W, Grupp IL, Grupp G, et al. Cardiac dysfunction ... The Prospective P2C2 HIV Multicenter Study. Circulation 2000;102:1542-8. Miller TL, Orav EJ, Colan SD, et al. Nutritional ... A lower body mass index is associated with cardiomyopathy in people with HIV infection: evidence from a case comparison study. ... Cardiac involvement in the acquired immunodeficiency syndrome: a multicentre clinical-pathological study. AIDS Res Hum ...
UK Prospective Diabetes Study (UKPDS) Group". Lancet. 352 (9131): 837-53. 1998. PMID [http://www.sciencedirect.com/science?_ob= ... 3. The study you refer to is only one study and is ten years out of date anyway. ... 1. The above study states that "a biologically active form of chromium in mammals, potentiates the effect of insulin". What ... An old study easily to hand may have been since shown to be wrong, in which case it's the obligation of the objector to show ...
"Prospective Studies". The University of Texas at Dallas. Retrieved 2010-05-21. "Confetti Cannons and Countdowns: Campus ... Center for Holocaust Studies Center for the Interdisciplinary Study of Museums Center for Translation Studies Center for Values ... "Center for Holocaust Studies". The University of Texas at Dallas. Retrieved 2010-05-03. "Center for the Interdisciplinary Study ... Center for Crime and Justice Studies Center for Global Collective Action Center for the Study of Texas Politics Institute for ...
McDonald, Ea; Gartland, D; Small, R; Brown, Sj (2015-04-01). "Dyspareunia and childbirth: a prospective cohort study". BJOG: An ... In one study frenulum breve was found in 50% of patients who presented with dyspareunia.[15] During vigorous or deep or tight ...
A prospective study in a Danish community". Lupus. 22 (11): 1185-91. doi:10.1177/0961203313498796. PMID 23873432.. ... Usually, these factors contribute to lupus by influencing the immune system.[4] Several studies also indicate a potential ...
Results of a long-term prospective study". American Journal of Diseases of Children. 121 (6): 469-73. doi:10.1001/archpedi. ... "Charity Navigator 2012 CEO Compensation Study" (PDF). November 2012. Retrieved 2014-03-30.. ... "Fetal Alcohol Spectrum Disorders Prevention: An Exploratory Study Of Women's Use Of, Attitudes Toward, And Knowledge About ...
... prospective studies had identified 270 individuals. Prospective studies review groups of individuals (e.g., selected emergency ... Five prospective studies have been carried out, to test the accuracy of out of body perceptions by placing "unusual targets in ... Near-death studies[edit]. Main article: Near-death studies. Bruce Greyson (psychiatrist), Kenneth Ring (psychologist), and ... Parnia 2001 study[edit]. In 2001, Sam Parnia and colleagues published the results of a year-long study of cardiac arrest ...
2014). "AWARE-AWAreness during REsuscitation-a prospective study". Resuscitation. 85 (12): 1799-805. doi:10.1016/j. ... "AWARE-AWAreness during REsuscitation-a prospective study". Resuscitation. 85 (12): 1799-1805. doi:10.1016/j.resuscitation. ... Aware II study[edit]. As of May 2016, a posting at the UK Clinical Trials Gateway website describes plans for AWARE II, a two- ... The results of the study were published in October 2014; both the launch and the study results were widely discussed in the ...
... a Prospective Cohort Study of Bites by Formally Identified Redback Spiders". Medical Journal of Australia (Prospective cohort ... a Prospective Cohort Study of Bites by Formally Identified Redback Spiders". Medical Journal of Australia (Comment, letter). ... "A Prospective Study of 750 Definite Spider Bites, with Expert Spider Identification". QJM. 95 (11): 723-731. doi:10.1093/qjmed/ ... Studies support the safety of antivenom, with around a 5% chance of an acute reaction, 1-2% of anaphylaxis and 10% chance of a ...
A prospective study". European Journal of Vascular and Endovascular Surgery. 34 (3): 361-6. doi:10.1016/j.ejvs.2007.03.020. ...
A prospective study". The British Journal of Psychiatry. 176: 440-3. doi:10.1192/bjp.176.5.440. PMID 10912219. Pantic I ( ... Studies such as one in 1998 led by Robert E. Kraut indicated that Internet can have an impact on a person's daily life and that ... The study concluded that there is a correlation between screen time and a decline in mental health. The following list of ... A study conducted on a variety of New Zealand Children's television shows showed that a mental illness reference appeared in 59 ...
A prospective study". J Bone Joint Surg Am. 88 (6): 1251-7. doi:10.2106/JBJS.E.00216. PMID 16757758. Frick SL (April 2006). " ...
A prospective study". Am J Sports Med. 31 (4): 585-589. doi:10.1177/03635465030310041801. PMID 12860549. S2CID 22497516. Thomas ... Imaging studies, such as ultrasound or MRI, may reveal anatomic abnormalities or masses responsible for the impingement. ...
Armson CJ, Pollard CW, Child cyclist injuries; a prospective study. 3 Feb Vol 144, Med.J.Aust. 1986. O'Rourke NA, Costello F, ... Studies of helmet use by injured cyclists were published from the late 1980s, some in Australia, both before and after helmet ... McDermott, F. T.; Lane, J. C.; Brazenor, G. A.; Debney, A. E. (1993). "The effectiveness of bicyclist helmets: a study of 1710 ... The results of a comparative study of the injury profiles of Victorian motorcyclist and bicyclist casualties were used by the ...
A prospective study]". Forsch Komplementärmed Klass Naturheilkd (in German). 12 (3): 148-51. doi:10.1159/000085212. PMID ... "No credible scientific studies have demonstrated the reliability of LBA for detecting any of the above conditions." Ernst ...
A prospective study". J Bone Joint Surg Br. 69 (5): 840-2. doi:10.1302/0301-620X.69B5.3680356. PMID 3680356. Archived from the ... The study suggested that treatment should not be based on the correction of a non-existent nail deformity. In some cases, ... In studies of diabetics, who need to avoid surgery when possible, nail bracing was found to be effective at providing immediate ... One study compared patients with ingrown toenails to healthy controls and found no difference in the shape of toenails between ...
a b c Patti McGill Peterson, The Young Socialist Movement in America from 1905 to 1940: A Study of the Young People's Socialist ... who encouraged prospective SSS teachers to read John Dewey's School and Society to provide a conceptual basis for their work.[ ...
A prospective Emperor first had to be elected King of the Romans (Latin: Rex Romanorum; German: römischer König). German kings ... International Studies Quarterly. 41 (3): 494. doi:10.1111/0020-8833.00053. JSTOR 2600793. Retrieved 10 April 2021. German " ... Contradicting the traditional view concerning that designation, Hermann Weisert has argued in a study on imperial titulature ...
... a meta-analysis of prospective cohort studies". Diabetes Research and Clinical Practice. 89 (3): 309-19. doi:10.1016/j.diabres. ... a systematic review and meta-analysis of prospective studies". European Journal of Epidemiology. 32 (5): 363-375. doi:10.1007/ ... a systematic review and dose-response meta-analysis of prospective cohort studies". Diabetologia. 59 (12): 2527-2545. doi: ... Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes". ...
Department of Linguistics, Literary and Aesthetical studies (LLE) (Nordic, Comparative Literature, Theatre Studies, Digital ... "http://www.uib.no/education/practical-information/prospective-students/finances-and-insurance".. External link in ,title=. ( ... The University of Bergen is the only institution in the Nordic countries where the study of psychology has been assigned to its ... The Faculty of Law was established as a separate faculty in 1980, with legal studies and research having been conducted at the ...
Kubba H, MacAndie C, Botma M, Robison J, O'Donnell M, Robertson G, Geddes N (2001). "A prospective, single-blind, randomized ... One study found it as effective as nasal cautery in the prevention of recurrent epistaxis in people without active bleeding at ...
A study involving 2408 donors (18-60 years) indicated that bone pain (primarily back and hips) as a result of filgrastim ... "Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National ... A study that surveyed 2408 donors found that serious adverse events (requiring prolonged hospitalization) occurred in 15 donors ... "One million haemopoietic stem-cell transplants: a retrospective observational study". Lancet Haematol. 2015 Mar 2(3): e91-100. ...
"Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae". PLoS Genet. 5 (2): ... "APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective Coronary Heart Disease Risk among UK healthy ...
The early European studies of what is now known as Lyme disease described its skin manifestations. The first study dates to ... "Prospective clinical evaluation of patients from Missouri and New York with erythema migrans-like skin lesions". Clinical ... The evolutionary history of Borrelia burgdorferi genetics has been the subject of recent studies. One study has found that ... Immunological studies[edit]. Exposure to the Borrelia bacterium during Lyme disease possibly causes a long-lived and damaging ...
"Prospective students". Association of Chiropractic Colleges. Archived from the original on 2009-08-14. Retrieved 2009-07-23.. ... Numerous controlled clinical studies of treatments used by chiropractors have been conducted, with conflicting results.[4] ... Studies of chiropractic intern clinical experience provides no evidence that chiropractors are trained to a level of a ... A 2010 study by questionnaire presented to UK chiropractors indicated only 45% of chiropractors disclosed with patients the ...
"Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis" ... Controlled Pilot Study ...
"A prospective study of maternal and fetal outcome in acute Lassa fever infection during pregnancy". BMJ. 297 (6648): 584-7. doi ... The study of the epidemiology of Lassa fever is complicated by a lengthy incubation period, which may be up to three weeks.[7] ... No study has proven presence in breast milk, but the high level of viremia suggests it may be possible.[6] ... where military biologists study infectious diseases, have a promising vaccine candidate.[17] They have developed a replication- ...
... including prospective cohort studies and experience sampling studies[40] can examine relationships over time.[41][42] OHP- ... a b Bigos, S., Battié, M., Spengler, D., Fisher, L., Fordyce, W., Hansson, T., & ... Wortley, M. (1991). A prospective study of ... A prospective study of ECA subjects who were followed one year after the initial interviews provided data on newly incident ... At least five studies of men have linked effort-reward imbalance with CVD.[79] Another large study links ERI to the incidence ...
... the BJCP also encourages prospective test-takers to study the available literature on styles and brewing. New style guidelines ... study program designed to teach aspiring beer enthusiasts about the essence of any kind of beer".[2] The BJCP certifies[3] and ...
... prospective cohort study". British Medical Journal. 344: e4026. doi:10.1136/bmj.e4026. PMC 3383863 . PMID 22735105.. CS1 maint ... While there are studies that show the health and medical benefits of weight loss, a study in 2005 of around 3000 Finns over an ... Health Study, an observational cohort study, found that low carbohydrate diets based on vegetable sources of fat and protein ... Similar conclusion is drawn by other studies,[6][28] and although other studies suggest that intentional weight loss has a ...
"Journal of Consciousness Studies. 9 (11): 2-29.. *^ William James (1896). "The dilemma of determinism". The Will to believe, ... The relevance of such prospective indeterminate activity to free will is, however, contested,[46] even when chaos theory is ... "Journal of Consciousness Studies. 6 (8-9): 279-93. Feelings or intuitions per se never count as self-evident proof of anything. ... Herbert James Paton (1971). "§2 Moral judgements are a priori". The Categorical Imperative: A Study in Kant's Moral Philosophy ...
... a prospective follow-up study". Journal of the American Academy of Child & Adolescent Psychiatry. 40 (4): 472-481. doi:10.1097/ ... In these studies, most of the patients have reported being very happy with the results and very few of the patients have ... Several studies tried to measure the quality of life and self-perceive physical health using different scales. Overall, ... A study reported an overall increase of masturbation frequencies exhibited in most transsexual individuals and 78% of them were ...
... meta-analysis and prospective studies". Journal of Clinical Psychopharmacology. 15 (4 Suppl 2): 16S-23S. doi:10.1097/00004714- ... A controlled study with moclobemide and phenelzine". Br J Psychiatry. 161 (3): 353-60. doi:10.1192/bjp.161.3.353. PMID 1393304. ... Studies in dogs revealed no toxicity relevant for humans. No evidence for a possible hepatic or cardiovascular toxicity was ... Chronic toxicity: In an 18-months-study in rats with 10 mg/kg no signs of chronic toxicity were noted, with 50 mg/kg and 250 mg ...
This degree requires two to three years of academic studies. Finally, one can study for an additional three years to obtain the ... In 1846, Parliament examined the education and training of prospective barristers and found the system to be inferior to that ... "Graduate Legal Studies". Columbia Law School. Retrieved 28 August 2015.. *^ "Graduate Programs - Yale Law School". Law.yale.edu ... individual study and the mentoring lawyer was expected to carefully select materials for study and guide the clerk in his study ...
Williamson DF, Pamuk E, Thun M, Flanders D, Byers T, Heath C. Prospective study of intentional weight loss and mortality in ... Body mass index and the risk of gout: a systematic review and dose-response meta-analysis of prospective studies.. European ... collaborative analyses of 57 prospective studies. Lancet. 2009-03, 373 (9669): 1083-96. PMC 2662372. PMID 19299006. doi:10.1016 ... BMJ (Comparative Study). 2008, 337: a494 [2016-01-20]. PMC 2500200. PMID 18617488. doi:10.1136/bmj.a494. (原始内容存档于2009-02-22).. ...
Prospective LDP-NKP Coalition 26,529,190. 44.49. 246 23,740,931. 39.69. 79 325. 67.71. 186. 185 ... This article incorporates public domain material from the Library of Congress Country Studies website http://lcweb2.loc.gov/frd ...
... the Louisville group had performed extensive basic science research and feasibility studies for many years prior to their first ... also considerable transparency and institutional review board oversight involved in the screening and selection of prospective ...
Clinical Characteristics and Visual Outcome in a Prospective Study» (en anglès). PLoS Negl Trop Dis, 2016 Maig 2; 10 (5), pp: ... Sroka J, Wójcik-Fatla A, Zwoliński J, Zajac V, et al «Preliminary study on the occurrence of Toxoplasma gondii in Ixodes ... An Autopsy Study» (en anglès). Ann Indian Acad Neurol, 2018 Abr-Jun; 21 (2), pp: 161-163. DOI: 10.4103/aian.AIAN_387_17. PMC: ... pros and cons of the Toxoplasma-human model in studying the manipulation hypothesis» (en anglès). J Exp Biol, 2013 Gen 1; 216 ( ...
Kato, I; Toniolo, P; Akhmedkhanov, A; Koenig, KL; Shore, R; Zeleniuch-Jacquotte, A. Prospective study of factors influencing ... The Harvard Study of Moods and Cycles. April 2006, 63 (4): 385-90 [28 September 2013]. doi:10.1001/archpsyc.63.4.385. (原始内容存档于 ... Predictive factors of age at menopause in a large Australian twin study. Hum Biol. 1998, 70 (6): 1073-91. PMID 9825597.. ... Risk of infertility in patients with celiac disease: a meta-analysis of observational studies. Arq Gastroenterol. 2014, 51 (2 ...
... a prospective, controlled study in 254 affected women. J. Clin. Endocrinol. Metab. 1999, 84 (1): 165-9. PMID 9920077. doi: ... The pattern is not very sensitive; a ratio of 2:1 or higher was present in less than 50% of women with PCOS in one study.[65] ... A review study. Diabetes & Metabolic Syndrome (Review). 2017. PMID 28416368. doi:10.1016/j.dsx.2017.03.030.. ... a systematic review and meta-analysis of 28 studies. Hum. Reprod. Update. 2012, 18 (6): 638-51. PMID 22824735. doi:10.1093/ ...
Four prospective American studies". Circulation 79 (1): 8-15. PMID 2642759. *↑ Espenshade PJ, Hughes AL (2007). "Regulation of ... a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths". Lancet 370 (9602): 1829-39. doi: ... a post-hoc analysis of the IDEAL and the EPIC prospective studies found an association between high levels of HDL cholesterol ( ... West of Scotland Coronary Prevention Study Group". N. Engl. J. Med. 333 (20): 1301-7. doi:10.1056/NEJM199511163332001. PMID ...
This was noted in a landmark study on the effects of sleep deprivation and error rate in an Intensive-care unit.[23][24] The ... Certain specialties, such as ophthalmology, radiology, anesthesiology, and dermatology, still require prospective residents to ... In 2007, the Institute of Medicine was commissioned by Congress to study the impact of long hours on medical errors. New ACGME ... The graduate medical students do not need to complete the residency because they study medicine in six years (three years for ...
... a prospective study". Am J Prev Med. 26 (5): 436-42. doi:10.1016/j.amepre.2004.02.013. PMID 15165661.. ... results from a randomized controlled study with bumetanide". J. Bone Miner. Res. 21 (1): 163-70. doi:10.1359/JBMR.051003. PMID ... double-blinded Latin-square multiple cross-over study in postmenopausal osteopenic women". Eur. J. Clin. Invest. 33 (1): 41-50 ...
52] ^ The Osaka Maternal and Child Health Study *^ a b c Appleby, Louis, Rachel Warner, Brian Faragher, and Anna Whitton. «A ... Gotlib, I.H., Whiffen, V.E., Wallace, P.M., and Mount, J.H. Prospective investigation of postpartum depression: factors ... "The long-term impact of postnatal depressed mood on mothers + child interaction: a preliminary study." Journal of Reproductive ... Controlled Study of Fluoxetine and Cognitive-Behavioural Counseling in the Treatment of Postnatal Depression». British Medical ...
"Journal of Military and Strategic Studies. 6 (3). ISSN 1488-559X.. *^ a b c d e Dave., Grossman, (2009). On killing : the ... The Pakistan Military Academy is analogous to Sandhurst, West Point or Tironut and undertakes training of the prospective ... A study of 783 infantry recruits". The Journal of Bone and Joint Surgery. British Volume. 76 (1): 20-22. ISSN 0301-620X. PMID ... As an example, the Coast Guard Academy is the only service academy that uses competitive admissions for prospective officer ...
Compare retrospective study. Source for information on prospective study: A Dictionary of Nursing dictionary. ... a systematic study of a group of individuals for a defined period or until the occurrence of a specified event (e.g. onset of ... Cohort Study , COHORT STUDY In the analytic method of epidemiological study called a cohort study, subsets of a defined ... prospective study (prŏ-spek-tiv) n. a systematic study of a group of individuals for a defined period or until the occurrence ...
Faculty of Graduate Studies and Research. Killam Centre for Advanced Studies. 2-29 Triffo Hall. University of Alberta Edmonton ... Thank you for your interest in graduate education and welcome to the Faculty of Graduate Studies and Research (FGSR) at the ... Students choose to pursue graduate studies at UAlberta for many reasons, including the depth and range of our academic ... Learn more about quality assurance standards of graduate studies at the University of Alberta. ...
Prospective Students. Getting into the Film Major. Film Studies is a much sought-after major, and our limited resources require ... Film studies faculty will evaluate applications based on performance in film studies classes (including but not limited to ... Students who are considering a Film Studies major should consult with the department chair as soon as possible in order to ... To be accepted into the Film Studies major, students are required to have completed two prerequisites, Film 304: History of ...
... BA Programmes for 2020 entry. Politics. Politics and International Studies. Politics and ... International Studies and Hispanic Studies. Politics, International Studies and Italian. Politics and International Studies ... Politics, International Studies and French. Politics, International Studies and German. Politics, ... As a PAIS student, you will work with experts on a wide variety of topics within politics and international studies. Whether ...
We hope you will consider choosing a course at Trinity for postgraduate study. At Trinity you will embark on an exciting new ... You are here Prospective Students Prospective Students. As a truly international university, we welcome applications from ... Prospective Students who wish to request a copy of the prospectus by post can email the Academic Registry ([email protected] ... We hope you will consider choosing a course at Trinity for postgraduate study. At Trinity you will embark on an exciting new ...
Study Programmes. The Section offers study opportunities at PhD, MPhil or MA level. The PhD and MPhil are full research degrees ... Postgraduate study at both research and taught-course level plays a central role in the Sections approach. Germanic Studies, ... On this programme you can specialise in a single area of study such as Germanic Studies or you can pursue a broader programme ... It houses the internationally unique Centre for Dutch and Flemish Studies and the Centre for Luxembourg Studies and supplies ...
Prospective Students Expand Menu Item Prospective Students * * * Degrees and Department Contacts * Doctorate ... Call Graduate Studies at (909) 537-5058 to make an appointment with Erma Cross, our Graduate Program Recruiter, or contact the ... Attn: Office of Graduate Studies, CH-123. 5500 University Parkway. San Bernardino, CA 92407. ... For more information, please contact the Office of Graduate Studies at 909-537-5058. ...
Accommodation Information for Prospective students. Prospective undergraduates. Accommodation information for prospective ... Prospective postgraduates. Information about accommodation options and application process for postgraduate students ... Imperials impactRead case studies about how Imperial research has made a difference ... International studentsStudents come from over 140 different countries to study at Imperial ...
Welcome, prospective Womens and Gender Studies student! Here youll find resources and information about the program, ... Womens and Gender Studies Program. University of Nebraska-Lincoln. 325 Louise Pound Hall. Lincoln, NE 68588-0319. This is an ... You will also study gender more broadly, which means you will look at feminine, masculine, and queer identities across time and ... With more than 30 majors in the college alone, specialized programs of study to match any interest area, the opportunity for ...
SJSU Home,College of Graduate Studies,Prospective Students. Prospective Students. .qi.smSAP { background-image:url(/aspis/ ... College of Graduate Studies. San José State University. td { font-size:100%; } .gcsc-branding { display:none; } .gsc-control- ...
STUDY DESIGN: A longitudinal, prospective, observational, cohort study.. OBJECTIVES: To describe the natural history of back ... Back pain during pregnancy: a prospective study.. Kristiansson P1, Svärdsudd K, von Schoultz B. ...
The College of Education Graduate Studies Office provides support for the application through admission process and handles the ... CSULB Home Colleges College of Education Graduate Studies Office Prospective Students Overview ... Prospective Students Overview. Thank you for your interest in Graduate Degree and Advanced Credential programs offered by the ... Interested in Teaching or Doctoral Study?. If you are interested in the Doctor of Education or an initial/preliminary teaching ...
A Prospective Study of Patient-Physician Communication About Resuscitation. Published in: Journal of the American Geriatrics ... DESIGN: Prospective cohort. SETTING: Five academic medical centers. PARTICIPANTS: Patients enrolled in the Study to Understand ... Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published ...
Prospective Infant Behavioral Study (PIBS). The Prospective Infant Behavioral Study (PIBS) study is currently enrolling ... This study involves two visits. The first involves a standardized assessment at birth that will help researchers learn more ... A second visit at 8 months of age will involve showing the infant videos on a screen that will help study personnel understand ...
... prospective student! Here youll find resources and information about our undergraduate programs, scholarships and financial ... Major in Classics and Religious Studies Classics and Religious Studies Classical Languages Careers in Classics Scholarships & ... Welcome, prospective student!. Here youll find resources and information about our undergraduate programs, scholarships and ... With over 30 majors in the college alone, specialized programs of study to match any interest area, the opportunity for hands- ...
ACFE online self-study courses feature: 24/7 access to courses through your Internet browser Save time and quickly earn CPE ... Online Self-Study Troubleshooting Guide: Problem: When I attempt to access my courses from "My Online Learning," the course ... ACFE online self-study courses are designed to run on all modern web browsers, but if you encounter a problem that is not ... Solution: You do not have to log in a second time to access your online self-study. You most likely reached the login page ...
The Commission has decided to locate the Institute for Prospective Technological Studies of the Joint Research Centre in ... Commission selects Seville for the Institute for Prospective Technological Studies. The Commission has decided to locate the ... The Commission has decided to locate the Institute for Prospective Technological Studies of the Joint Research Centre in ... cordis.europa.eu/article/id/1682-commission-selects-seville-for-the-institute-for-prospective-technological-studies ...
... study showed that rhythm-control treatment of patients with atrial fibrillation (AF) offered no survival... ... This study was funded partly by the Swedish Heart-Lung Foundation, but the foundation had no active role in the study. ... a prospective cohort study. Lancet 359(9320):1805-1811PubMedCrossRefGoogle Scholar ... Prospective Randomized Study of Ventricular Failure and the Efficacy of Digoxin) and RADIANCE (Randomized Assessment of Digoxin ...
Comparative Study; Multicenter Study; Research Support, Non-U.S. Govt ... Pregnancy outcomes after uterine artery occlusion: prospective multicentric study.. Holub Z1, Mara M, Kuzel D, Jabor A, Maskova ... Prospective, clinical multicentric study.. SETTING: Endoscopic center in the department of obstetrics and gynecology at a ...
Study Finds Washington Prospective teachers who earn licenses to practice have higher ... SAT scores than most college-bound high school seniors, according to a study released here at the recent annual meeting of the ... br/>

Prospective Teachers SAT Scores Higher Than Believed, ... Prospective Teachers SAT Scores Higher Than Believed, Study ... Prospective Teachers SAT Scores Higher Than Believed, Study Finds. Washington Prospective teachers who earn licenses to ...

Prospective Study of Hyperglycemia and Cancer Risk. Pär Stattin, Ove Björ, Pietro Ferrari, Annekatrin Lukanova, Per Lenner, ... Prospective Study of Hyperglycemia and Cancer Risk. Pär Stattin, Ove Björ, Pietro Ferrari, Annekatrin Lukanova, Per Lenner, ... A Prospective Study of Overall Diet Quality and Risk of Type 2 Diabetes in Women ...
In a prospective cohort study, we examined and followed participants enrolled in the Copenhagen General Population Study ... Incidental lymphopenia and mortality: a prospective cohort study. Marie Warny, Jens Helby, Børge Grønne Nordestgaard, Henrik ... Incidental lymphopenia and mortality: a prospective cohort study. Marie Warny, Jens Helby, Børge Grønne Nordestgaard, Henrik ... In this prospective cohort study, we found that incidental lymphopenia was associated with a 1.6-fold increase in risk of all- ...
Prospective Study of Hyperglycemia and Cancer Risk. Pär Stattin, Ove Björ, Pietro Ferrari, Annekatrin Lukanova, Per Lenner, ... Prospective Study of Hyperglycemia and Cancer Risk. Pär Stattin, Ove Björ, Pietro Ferrari, Annekatrin Lukanova, Per Lenner, ... In this prospective cohort study, abnormal glucose metabolism was associated with a statistically significantly increased risk ... Here, we report the results from a prospective study in northern Sweden, with the aim to estimate the relationship of ...
ACRODAT Prospective Evaluation Study. The safety and scientific validity of this study is the responsibility of the study ... Prospective. Official Title:. Post-marketing Surveillance Study to Evaluate the Clinical Utility of ACRODAT in an International ... Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More ... Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More ...
They are especially appropriate to study rare exposures or exposures for which randomization is not possible for practical or ... Cohort studies form a suitable study design to assess associations between multiple exposures on the one hand and multiple ... Cohort studies: prospective versus retrospective Nephron Clin Pract. 2009;113(3):c214-7. doi: 10.1159/000235241. Epub 2009 Aug ... Prospective and retrospective cohort studies have higher accuracy and higher efficiency as their respective main advantages. In ...
... study_of_life_stress_and_d.html?id=jOFJAQAAIAAJ&utm_source=gb-gplus-shareA prospective study of life stress and depression. ... 0 Reviewshttps://books.google.com/books/about/A_prospective_study_of_life_stress_and_d.html?id=jOFJAQAAIAAJ ... books.google.comhttps://books.google.com/books/about/A_prospective_ ...
Tom Weishaar explains that prospective observational studies examining the associated effects of vitamin D status have to be ... Ideally, prospective observational studies will have multiple vitamin D measurements during the course of the study. If not, ... Some pitfalls of prospective observational studies in vitamin D research. Posted on: September 21, 2013 by [email protected] ... 2 Responses to Some pitfalls of prospective observational studies in vitamin D research. * allometric24. September 23, 2013 at ...
You are thinking about whether Slavic Studies would be the right choice for you? We have put together some good reasons. You ... Information for prospective students You are thinking about whether Slavic Studies would be the right choice for you? We have ... The Faculty of Linguistics, Literature and Cultural Studies has compiled some information for prospective students on its ... Language skills in the respective language to be studied do not need to be certified in advance of the course of study. If you ...
Study design: A longitudinal, prospective, observational, cohort study. Objectives: To describe the natural history of back ... Back pain during pregnancy: a prospective study Spine (Phila Pa 1976). 1996 Mar 15;21(6):702-9. doi: 10.1097/00007632-199603150 ...
  • Prospective cohort studies are typically ranked higher in the hierarchy of evidence than retrospective cohort studies and can be more expensive than a case-control study. (wikipedia.org)
  • One of the advantages of prospective cohort studies is they can help determine risk factors for being infected with a new disease because they are a longitudinal observation over time, and the collection of results is at regular time intervals, so recall error is minimized. (wikipedia.org)
  • Cohort studies form a suitable study design to assess associations between multiple exposures on the one hand and multiple outcomes on the other hand. (nih.gov)
  • Prospective and retrospective cohort studies have higher accuracy and higher efficiency as their respective main advantages. (nih.gov)
  • In addition to possible confounding by indication, cohort studies may suffer from selection bias. (nih.gov)
  • If one is aware of this, cohort studies can form a potent study design in nephrology producing, in general, highly generalizable results. (nih.gov)
  • Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies. (nih.gov)
  • A meta-analysis of prospective cohort studies was performed to investigate the effect of PA on hypertension risk. (nih.gov)
  • PubMed and Embase databases were searched to identify all related prospective cohort studies. (nih.gov)
  • Thirteen prospective cohort studies were identified, including 136,846 persons who were initially free of hypertension, and 15,607 persons developed hypertension during follow-up. (nih.gov)
  • We therefore examined the prospective, independent association of consumption of baked, boiled, or mashed potatoes, French fries, and potato chips with incident hypertension in three large cohort studies that included 187 453 participants with more than 20 years of follow-up. (bmj.com)
  • BACKGROUND: Few prospective cohort studies of workplace low back pain (LBP) with quantified job physical exposure have been performed. (cdc.gov)
  • However, several recent cohort studies found a positive association between HDL-C level and intracerebral hemorrhage. (cdc.gov)
  • We performed a systematic search of PubMed, Embase, and Web of Science databases through July 30, 2020, for prospective cohort studies that reported the HDL-C-stroke association and extracted the estimate that was adjusted for the greatest number of confounding factors. (cdc.gov)
  • We included 29 articles, which reported on 62 prospective cohort studies including 900,501 study participants and 25,678 with stroke. (cdc.gov)
  • Many prospective cohort studies reported that a high-density lipoprotein cholesterol (HDL-C) level protected against the development of stroke (5-11). (cdc.gov)
  • We explored the feasibility of pooling data from cohort studies of cancer incidence to investigate second cancer etiology. (aacrjournals.org)
  • Pooling data from cohort studies to investigate nontreatment risk factors for second primary cancers seems feasible but there are important methodologic issues-some of which are barriers to specific research questions-that require special attention. (aacrjournals.org)
  • To quantitatively assess this association, we conducted a meta-analysis of prospective cohort studies. (cambridge.org)
  • Students choose to pursue graduate studies at UAlberta for many reasons, including the depth and range of our academic offerings, the diversity of the culture and ideas found here, and the top rankings of our graduate programs. (ualberta.ca)
  • Students who are considering a Film Studies major should consult with the department chair as soon as possible in order to receive advising regarding the major. (wesleyan.edu)
  • To be accepted into the Film Studies major, students are required to have completed two prerequisites, Film 304: History of World Cinema to the 1960s and Film 307: The Language of Hollywood: Styles, Storytelling, and Technology, with a suitable grade in both. (wesleyan.edu)
  • Because of the prerequisites and major requirements, students transferring to Wesleyan beginning their junior year are not able to declare the Film Studies major. (wesleyan.edu)
  • Because communication studies is a generalist degree, students go into a variety of positions/programs upon graduation. (usm.edu)
  • As a truly international university, we welcome applications from prospective postgraduate students anywhere in the world. (tcd.ie)
  • Prospective Students who wish to request a copy of the prospectus by post can email the Academic Registry ( [email protected] ) with their name and postal address or download a digital copy below. (tcd.ie)
  • The regulations which govern students admission to, progression on, and examination on the research register are available in the University of Dublin Calendar Part III and all prospective and current students are strongly recommended to familiarise themselves with these. (tcd.ie)
  • If you would like to study but still have a lot of questions about what and how, then we urge you take advantage of our advising services for prospective students (offered in German only). (uni-hamburg.de)
  • Our students also find it possible to take up part-time work alongside their studies, whether on projects within the Department or more widely. (dur.ac.uk)
  • By studying abroad, you are joining a community of students that make up less than 10% of college undergraduates nationwide. (csuchico.edu)
  • With more than 30 majors in the college alone, specialized programs of study to match any interest area, the opportunity for hands-on experience through our nationally acclaimed undergraduate research program and a campus located at the heart of an innovative college city community of more than 250,000 people, the University of Nebraska-Lincoln offers the ideal Big Ten collegiate experience for students at an affordable cost. (unl.edu)
  • The PRAXIS passing rates for candidates who attended institutions accredited by the National Council for Accreditation of Teacher Education were 'somewhat higher' than for those who did not, despite the fact that SAT scores for entering students are higher in non-NCATE institutions, the study found. (edweek.org)
  • The Faculty of Linguistics, Literature and Cultural Studies has compiled some information for prospective students on its website. (tu-dresden.de)
  • The baccalaureate degree program in Human Development and Family Studies provides students with an understanding of human development and family relationships across the lifespan. (kent.edu)
  • The graduate program in HDFS provides students with advanced knowledge in human development and family studies. (kent.edu)
  • At the master's level, students will develop community research skills and will be prepared for leadership positions within social service agencies, teaching at junior and community colleges or to pursue doctoral level study. (kent.edu)
  • Computational Linguistics is ideal for students with a background in Computer Science and Linguistics who want to study in an interdisciplinary, innovative environment. (uni-stuttgart.de)
  • In the 3rd semester, students can study abroad and use the credit points for their M.Sc. (uni-stuttgart.de)
  • Students who are missing certain qualifications may be granted admission on the condition that they acquire these qualifications before or during the course of their studies, for example by passing additional modules ("Auflagen" in German). (uni-stuttgart.de)
  • Tokyo Tech's International Office supports various opportunities for graduate students to study abroad. (titech.ac.jp)
  • Many of these agreements include tuition waiver programs that allow Tokyo Tech graduate students to study at a partner university for a semester or a period of up to one year while enrolled at Tokyo Tech. Both Tokyo Tech and the partner university receive and dispatch a designated number of students according to the particular agreement. (titech.ac.jp)
  • TASTE provides financial support to Tokyo Tech students who will participate in a summer intensive language program, such as STEP offered by the University of Washington, before beginning a mid- to long-term study abroad or research program through one of Tokyo Tech's exchange programs. (titech.ac.jp)
  • Prospective students can apply to either or both of the departments. (uchicago.edu)
  • Students who plan to concentrate on Ottoman and Turkish Studies should apply to Ottoman and Turkish Studies program at NELC. (uchicago.edu)
  • Through the university's Division of International Programs, students may take advantage of either short- or long-term study opportunities abroad. (niu.edu)
  • We invite prospective students to contact us at California Western School of Law as they consider where to study law. (cwsl.edu)
  • At California Western we are always eager to meet prospective students, and current students are happy to reach out and welcome you to our community. (cwsl.edu)
  • By taking internships and project courses that are credited towards the bachelor's and master's programs, students can get to know these institutions as well as companies during their studies. (uni-potsdam.de)
  • Students can study a wide variety of undergraduate subjects in the College of Medical, Veterinary and Life Sciences. (gla.ac.uk)
  • There are many opportunities for funding available to prospective undergraduate students. (gla.ac.uk)
  • In a multicenter prospective cohort study of critically ill adults with severe hypotension, we recorded MAP and vasopressor doses hourly. (plos.org)
  • In this multicenter, prospective observational study, the patient-level average MAP while receiving vasopressors for severe hypotension was 75 mmHg, approximately 10 mmHg above current recommendations and stated practices. (plos.org)
  • We conducted a multicenter prospective observational study. (plos.org)
  • The participants involved with the study constituted the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort - the same population involved with a 15-year multicenter prospective cohort study investigating metabolic, dietary, lifestyle, and environmental factors in relation to cancer and other chronic diseases. (naturalnews.com)
  • In the frame of multicenter research studies, biobanks ensure the harmonization and traceability of the prospective collection of quality samples. (intechopen.com)
  • When a prospective multicenter research project is designed, multiple variables must be considered such as the number and type of donations, recruitment sites and analytical laboratory locations, pre-analytical requirements of samples and derivatives obtained, and processing and storage facilities. (intechopen.com)
  • 14 - 16 In a 2018 study involving 98 344 participants from the general population of Denmark, we found that lymphopenia was associated with a high risk of infectious disease. (cmaj.ca)
  • Kent State's program focuses on child and adolescent development, adult development and aging, biological aspects of human development, family studies, intervention research, and developmental research methods. (kent.edu)
  • METHODS: From Feb 2011 to Jan 2012, 83 BPH patients were enrolled in our study. (mendeley.com)
  • and c) assess the clinical/paraclinical features that help differentiate PINSs from multiple sclerosis (MS). METHODS: In this prospective cohort study, adult inpatients with PINSs underwent extensive diagnostic assessment and therapeutic protocols at inclusion and during a minimum 2-year follow-up. (biomedsearch.com)
  • METHODS/DESIGN: A multi-center prospective cohort study has been incepted to quantify risk factors for LBP and potentially develop improved methods for designing and analyzing jobs. (cdc.gov)
  • A total of 265 patients who were prescribed oral cannabinoid therapy as part of usual medical practice were enrolled into this prospective observational study. (springer.com)
  • PARTICIPANTS: Patients enrolled in the Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments who had not communicated with their physicians about CPR at admission to a hospital for life-threatening illness (n = 1288). (rand.org)
  • In a prospective cohort study, we examined and followed participants enrolled in the Copenhagen General Population Study between November 2003 and April 2015. (cmaj.ca)
  • Participants 62 175 women in Nurses' Health Study, 88 475 women in Nurses' Health Study II, and 36 803 men in Health Professionals Follow-up Study who were non-hypertensive at baseline. (bmj.com)
  • If they agree and sign a consent form, they will then become study participants. (clinicaltrials.gov)
  • We identified twenty studies of coffee consumption and total mortality, including 129 538 cases of deaths among the 973 904 participants. (cambridge.org)
  • We hope you will consider choosing a course at Trinity for postgraduate study. (tcd.ie)
  • Postgraduate study at both research and taught-course level plays a central role in the Section's approach. (sheffield.ac.uk)
  • A prospective cohort study is a longitudinal cohort study that follows over time a group of similar individuals (cohorts) who differ with respect to certain factors under study, to determine how these factors affect rates of a certain outcome. (wikipedia.org)
  • To perform a comprehensive clinicopathological study in these subjects with complete virological, immunophenotypic, and molecular characterization of retrieved tumor tissues and peripheral blood samples for purposes of identifying prognostic and predictive biomarkers of clinical outcome (i.e. treatment response, freedom from disease progression, and overall survival) in which to begin to frame pragmatic, risk-adapted therapeutic interventions suitable for the resource constrained setting in sub-Saharan Africa. (clinicaltrials.gov)
  • Individuals were followed as part of a longitudinal study to investigate in details the long-term outcome of Chikungunya. (plos.org)
  • We have conducted a prospective longitudinal study to investigate in details long-term outcome of CHIKV infection. (plos.org)
  • We report a prospective study of the outcome of clinically diagnosed infections in patients presenting to UK general practitioners. (prohealth.com)
  • The objectives were to assess micronutrient intake and blood biomarkers prospectively in pregnant adolescents recruited to the About Teenage Eating (ATE) Study and to determine associations with pregnancy outcome. (unboundmedicine.com)
  • The distinguishing feature of a prospective cohort study is that at the time that the investigators begin enrolling subjects and collecting baseline exposure information, none of the subjects have developed any of the outcomes of interest. (wikipedia.org)
  • After baseline information is collected, subjects in a prospective cohort study are then followed "longitudinally," i.e. over a period of time, usually for years, to determine if and when they become diseased and whether their exposure status changes outcomes. (wikipedia.org)
  • Proportion of patients in each group achieving IGF-I normalisation at any time (post-baseline) during the course of the study, where IGF-I normalisation is defined as an (age adjusted) IGF-I value within the normal range defined by the local lab. (clinicaltrials.gov)
  • The study is based on data collected in the Multi-Ethnic Study of Atherosclerosis (MESA), which collected baseline data on individuals in the U.S. who were free of heart disease from July 2000 through September 2002. (vitamindcouncil.org)
  • The primary study outcomes were change in IPSS, BP, and heart rate from baseline. (dovepress.com)
  • Subjects from the Epidemiology of Diabetes Complications (EDC) Study were clinically examined at baseline and then biennially. (diabetesjournals.org)
  • The type of dietary questionnaire used varied according to study centers and included: Self- or interviewer-administered semi-quantitative food frequency questionnaires (FFQs) with an estimation of individual average portions or with the same standard portion assigned to all subjects, or diet history questionnaires combining an FFQ and 7-day dietary records. (naturalnews.com)
  • Thank you for your interest in graduate education and welcome to the Faculty of Graduate Studies and Research (FGSR) at the University of Alberta! (ualberta.ca)
  • Follow a step-by-step process to apply to graduate studies on-line. (ualberta.ca)
  • Learn more about quality assurance standards of graduate studies at the University of Alberta. (ualberta.ca)
  • If you are officially admitted to our university, you will be required to submit official transcripts to the Office of Graduate Studies to secure your enrollment for the following term. (csusb.edu)
  • Call Graduate Studies at (909) 537-5058 to make an appointment with Erma Cross, our Graduate Program Recruiter, or contact the coordinator of the program you are interested in. (csusb.edu)
  • For more information, please contact the Office of Graduate Studies at 909-537-5058. (csusb.edu)
  • Prepare for graduate study, expand your professional knowledge or explore an area of personal interest with Penn's resources and support. (upenn.edu)
  • The College of Education Graduate Studies Office provides support for the application through admission process and handles the paper, program application for the Master's Degree and Advanced Credential programs. (csulb.edu)
  • Visit the graduate program page for more details about advanced degrees in Human Development and Family Studies. (kent.edu)
  • The Graduate Studies program at Eastman offers merit-based funding in the form of Graduate Awards. (rochester.edu)
  • The Strengthening the Reporting of OBservational studies in Epidemiology (STROBE) recommends that authors refrain from calling a study 'prospective' or 'retrospective' due to these terms having contradictory and overlapping definitions. (wikipedia.org)
  • Most recently, nested case-control molecular epidemiology studies and occupational exposure analyses of lung cancer, brain cancer, and non-Hodgkin lymphoma have been conducted. (cancer.gov)
  • Film studies faculty will evaluate applications based on performance in film studies classes (including but not limited to grades) and any other factors deemed pertinent. (wesleyan.edu)
  • The Faculty of Management Studies focuses on management education more than just business management. (fms.edu)
  • Faculty members in Ottoman and Turkish Studies are affiliated with either the Department of Near Eastern Languages and Civilizations (NELC) or the History Department (or both). (uchicago.edu)
  • In cooperation with International Programs, the School of Art has offered foreign study tours each year, directed by faculty members in art. (niu.edu)
  • The purpose of this post marketing surveillance study is to prospectively evaluate whether patients monitored by ACRODAT® with appropriate clinical decisions based on disease activity status will benefit from improved treatment outcomes both in the short and in the long term. (clinicaltrials.gov)
  • This study was conducted to assess prospectively the frequency of cognitive deficits in children with cerebral malaria. (aappublications.org)
  • To determine the spectrum and natural history of lymophoproliferative disorders in Nairobi, Kenya by prospectively recruiting subjects with biopsy-proven malignant lymphoma including non-Hodgkin's and Hodgkin's lymphoma regardless of age, sex and HIV-serostatus (cohort study), who are seen at the Kenyatta National Hospital for treatment. (clinicaltrials.gov)
  • This study prospectively investigated the risk factors for distal symmetrical polyneuropathy (DSP) in a cohort of childhood-onset IDDM patients. (diabetesjournals.org)
  • The first objective of this study was to examine the incidence of problematic prescription cannabinoid use (PPCBU) over a 12-month period among patients initiating cannabinoid therapy. (springer.com)
  • Findings from the present study could have implications for clinicians considering the use of cannabinoids for the management of patients with medical conditions. (springer.com)
  • Although results indicated that the majority of patients included in this study did not reach cutoff scores on the three main PPCBU outcomes, our findings suggest that PPCBU should be routinely assessed and monitored over the course of cannabinoid therapy, particularly among patients with a history of psychiatric or substance use problems. (springer.com)
  • The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study showed that rhythm-control treatment of patients with atrial fibrillation (AF) offered no survival advantage over a rate-control strategy. (springer.com)
  • In a subgroup analysis of that study, it was found that digoxin increased the death rate [relative risk (RR) = 1.42), but it was suggested that this may have been attributable to prescription of digoxin for patients at greater risk of death, such as those with congestive heart failure (CHF). (springer.com)
  • No study has investigated a priori the effect of digoxin on mortality in patients with AF. (springer.com)
  • Using data from the Registry of Information and Knowledge about Swedish Heart Intensive care Admissions (RIKS-HIA), we studied the 1-year mortality among patients admitted to coronary care units with AF, CHF, or AF+CHF with or without digoxin ( n = 60,764) during 1995-2003. (springer.com)
  • Patients not followed up with ACRODAT® will be followed-up in accordance with the standard medical practice of the hospital where they have been recruited, until study completion (Standard Practice arm). (clinicaltrials.gov)
  • Therefore, patients who experienced pain after endodontic treatment and did not require active treatment were excluded from those studies [ 6 ]. (hindawi.com)
  • Patients in Kenya who agree to be in this study will let the resesarchers look at their medical record, follow their normal cancer care, and have blood drawn to look at different proteins and viruses. (clinicaltrials.gov)
  • In a prospective encounter-based study, patients with CF were followed until at least age 6 years and information about weight, height and lung disease at both age 3 and 6 years was recorded. (leo.org)
  • The patients with age less than 50, other drugs therapy, AUR history, prostate cancer, diabetes, acute prostatitis, history of baldder or prostate surgery were excluded from the study. (mendeley.com)
  • In 2006, a Chikungunya outbreak occurred in La Réunion Island, during which we constituted a prospective cohort of viremic patients (n = 180) and defined the clinical and biological features of acute infection. (plos.org)
  • The aim of this study was to measure actual MAP values among hypotensive patients receiving vasopressor therapy. (plos.org)
  • In an excellent example of the kind of comparative effectiveness research needed to distinguish the relative quality of competing treatment approaches, researchers in Alberta, Canada studied the relative costs and benefits of lumbar microdisckectomy and chiropractic spinal manipulation for patients with low back pain and sciatica associated with lumbar disk herniation for whom usual medical care had failed. (chiro.org)
  • In the Canadian study, patients receiving chiropractic care averaged 21 visits during their course of care. (chiro.org)
  • The purpose of this study was to compare the clinical efficacy of spinal manipulation against microdiskectomy in patients with sciatica secondary to lumbar disk herniation (LDH). (chiro.org)
  • The purpose of this pilot study was to compare clinical outcomes among patients failing nonspecific conservative care (in which the common denominator was time elapsed from onset of symptoms) who were then subjected to a regulated spinal manipulation regimen or to a traditional surgical microdiskectomy. (chiro.org)
  • Questionnaires assessing fatigue and psychiatric morbidity were sent to all patients aged 18-45 years in the study practices. (prohealth.com)
  • In a prospective study published this month, patients with cancer of unknown primary who were tested using BioTheranostics' CancerType ID assay, and who then received chemotherapy specific to their predicted tumor of origin, survived longer on average than expected for standard CUP treatment. (genomeweb.com)
  • Retrospective studies of patients with non-insulin-dependent diabetes mellitus (NIDDM) have suggested that microalbuminuria predicts early all-cause (mainly cardiovascular) mortality independently of arterial blood pressure. (diabetesjournals.org)
  • The objective of this study was to assess the efficacy and safety of alfuzosin 10 mg monotherapy or combined antihypertensive medication on blood pressure (BP) in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS) with or without antihypertensive medication. (dovepress.com)
  • This study shows that alfuzosin 10 mg is effective and well tolerated in patients with BPH/LUTS with or without antihypertensive medications. (dovepress.com)
  • The intent of the editorial was to voice caution about the indiscriminate use of quinine for idiopathic muscle cramps in older patients, not to limit its use for patients with conditions such as amyotrophic lateral sclerosis who were excluded from the study of Garrison et al. (cmaj.ca)
  • This study will evaluate how the cardiovascular system interacts with mechanical hearts to provide blood flow to the body during exercise. (bioportfolio.com)
  • The purpose of this study was to evaluate the incidence, severity, and types of PEP presenting after root canal treatment in teeth with vital or necrotic pulp and after retreatment. (hindawi.com)
  • The aim of our study was to evaluate the effect of finasteride on PSA in Chinese population. (mendeley.com)
  • Over the years, data and biological samples (blood/buccal cell and urine) collected in the SWHS have been used to evaluate many important etiologic hypotheses and support multiple studies. (cancer.gov)
  • 3 However, several retrospective studies suggested that cognitive deficits in children with CM are more frequent (occurring in 11%-28% of children with CM) and persist for a far longer time (3-9 years after the CM episode) than neurologic deficits. (aappublications.org)
  • This content of the study program Natural Language Processing was optimized and is now available under Studienwahl-Kompass Natural Language Processing . (uni-stuttgart.de)
  • The CSU, Chico Study Abroad Office is excited to help you through this process. (csuchico.edu)
  • After that, you can begin to explore the many other pages about where to go, why to go, and what you can study while abroad. (csuchico.edu)
  • Once you have done all of your research, attended a Study Abroad Information Session and meet with our country-specific Peer Advisors and/or study abroad advisor in order to select a specific program . (csuchico.edu)
  • When studying abroad in Tanzania with SFS, you can expect to have a very unique and a once-in-a-lifetime study abroad experience. (fieldstudies.org)
  • Studying abroad: what opportunities does my study program offer? (uni-stuttgart.de)
  • Studying abroad: what opportunities does the University of Stuttgart has to offer? (uni-stuttgart.de)
  • General information about several of the programs and scholarships for studying abroad can be found below. (titech.ac.jp)
  • For a complete list of programs and information about each one, please visit Study Abroad . (titech.ac.jp)
  • Interested in Teaching or Doctoral Study? (csulb.edu)
  • The GIGA Doctoral Programme (DP) is a three-year structured programme for junior researchers, in which they can pursue their research and professional development, particularly in the field of comparative area studies (CAS). (jobs.ac.uk)
  • I gained invaluable classroom experience that enabled me to move seamlessly from doctoral study to professional life. (rochester.edu)
  • DESIGN: Prospective cohort. (rand.org)
  • The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. (plos.org)
  • Currently, two ongoing study tour opportunities each year include "Exploring Contemporary Graphic Design and Design Education in Poland" in association with the Academy of Fine Arts in Katowice, Poland, and a resident experience during the summer in Rome, Italy. (niu.edu)
  • The program offers a solid foundation in media and communication studies while also permitting you to design a highly individualized program of study. (umich.edu)
  • In seasonal-interannual West African climate studies, the latest evidence from satellite data analyses and modeling studies confirm that the West African region has a climate which is particularly sensitive to land surface processes and there is a strong coupling between land surface processes and regional climate at intraseasonal/seasonal scales. (hindawi.com)
  • Other studies have examined the influence of social support on depression scores in peripartum mothers by multiple linear regression analyses. (nature.com)
  • Five substantially smaller prospective studies ( 4 - 8 ) with a total number of ∼11,000 incident cases of cancer also have reported data on associations between fasting or postload glucose and cancer incidence or mortality. (diabetesjournals.org)
  • Nevertheless, no study has evaluated the incidence and severity of PEP after re-treatment and after initial RCT of teeth with vital or necrotic pulp [ 3 ]. (hindawi.com)
  • Incidence rates and survival following the first primary varied among the cohorts, but most of the heterogeneity could be explained by characteristics of the study populations (age, sex, smoking, and screening rates). (aacrjournals.org)
  • It houses the internationally unique Centre for Dutch and Flemish Studies and the Centre for Luxembourg Studies and supplies the Directors of the University's interdisciplinary Research Centres in Nineteenth-Century Studies, Gender Studies in Europe, and Dutch Studies. (sheffield.ac.uk)
  • The Commission has decided to locate the Institute for Prospective Technological Studies of the Joint Research Centre in Seville. (europa.eu)
  • The Institute for Prospective Technological Studies (IPTS), located in Seville, Spain, is one of the seven institutes of the Joint Research Centre (JRC), a Directorate-General of the European Commission (EC). (wikipedia.org)
  • This study was funded by the CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), Institut Pasteur, Inserm (Institut National de la Santé et de la Recherche Médicale), Labex IBEID, Fondation pour la Recherche Médicale, BNP-Paribas Foundation and Mairie de Paris. (plos.org)
  • There are two main areas of communication: a social scientific approach to the study of human communication (quantitative and qualitative studies) and a humanistic/rhetorical approach (study of public persuasive messages). (usm.edu)
  • The idea that chronic fatigue has an infectious origin has become popular, but the main evidence for such an association has come from retrospective case-control studies, which are subject to ascertainment bias. (prohealth.com)
  • We conducted a matched cohort study during an epidemic in French Guiana to compare events and pregnancy outcomes between two paired groups of pregnant women: women having presented with symptomatic dengue during pregnancy (n = 73) and women having had neither fever nor dengue during pregnancy (n = 219). (archives-ouvertes.fr)
  • Postinfectious neurologic syndromes: A prospective cohort study. (biomedsearch.com)
  • Film Studies is a much sought-after major, and our limited resources require us to place restrictions on admission. (wesleyan.edu)
  • There are no special admission requirements for a Bachelor's degree in Slavic Studies at TU Dresden. (tu-dresden.de)
  • In the video below you can find valuable info regarding the programme, admission process, general info on studying in HSE University and much more. (hse.ru)
  • Recently, total cancer risk was reported to be modestly increased in women and men with elevated levels of fasting glucose in a very large cohort study of 1.3 million Korean men and women with 53,833 incident cases of cancer ( 3 ). (diabetesjournals.org)
  • Named as one of the UK's 'Big Five' politics departments by the Political Studies Association, PAIS (Politics and International Studies) is one of the largest and most highly regarded departments of our kind in the UK, with a global reputation for research excellence and dedication to teaching and learning. (warwick.ac.uk)
  • Germanic Studies, founded in the 1880s, has a distinguished history of research across the range of Germanic languages, literature and society from the Middle Ages to the modern period. (sheffield.ac.uk)
  • Germanic Studies conducts research in Dutch and Luxembourgish as well as in German. (sheffield.ac.uk)
  • We will consider applications from candidates with other qualifications who can provide evidence of very strong motivation for research in Germanic Studies. (sheffield.ac.uk)
  • The prospective study is important for research on the etiology of diseases and disorders. (wikipedia.org)
  • At the time of commencement of this study, most NDE research was retrospective (Moody 1975, Ring 1980, Sabom 1982, Morse et al. (iands.org)
  • She read about NDEs and in 1997 decided to undertake her own research by conducting a long term prospective study (the UKs first long term study). (iands.org)
  • The prospective study formed part of a much bigger research project into NDEs for which Dr. Sartori was awarded a PhD in 2005 at the University of Wales, Lampeter. (iands.org)
  • To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. (clinicaltrials.gov)
  • The GIGA German Institute of Global and Area Studies / Leibniz-Institut für Globale und Regionale Studien is an independent social science research institute based in Hamburg. (jobs.ac.uk)
  • Our Ph.D. program is internationally recognized in several areas of teaching and research, including Media Psychology, Political Communication, Critical Media Studies, and Global and Comparative Media. (umich.edu)
  • The Institute of Buddhist Studies offers a range of programs and enrollment options. (shin-ibs.edu)
  • The researchers looked at records for 160,000 candidates who took the PRAXIS 2 tests, which measure prospective teachers' knowledge of pedagogy and specific subjects, between 1995 and 1997 and had also taken the SAT college-entrance exam in the past 20 years. (edweek.org)
  • In 2012 the researchers obtained a stored blood sample for each individual in the study and tested the samples for 25(OH)D, the marker of vitamin D status. (vitamindcouncil.org)
  • This study will help researchers learn more about non-Hodgkin's lymphoma and Hodgkin's lymphoma and how it is treated in Kenya. (clinicaltrials.gov)
  • Researchers say increased diversity in genomic studies will benefit all, PBS NewsHour reports. (genomeweb.com)
  • Natural News ) A team of European researchers conducted a prospective analysis of the association between the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS) score of foods and cancer risk in a large and diverse European population. (naturalnews.com)
  • Studies investigating the effect of high-density lipoprotein cholesterol (HDL-C) on stroke and stroke subtypes have reached inconsistent conclusions. (cdc.gov)
  • Pregnancy outcomes after uterine artery occlusion: prospective multicentric study. (nih.gov)
  • They are especially appropriate to study rare exposures or exposures for which randomization is not possible for practical or ethical reasons. (nih.gov)
  • A prospective, population-based study was conducted in fifth-grade children (∼10 years of age) from Framingham, Massachusetts. (aappublications.org)
  • The Study of Nevi in Children is a prospective population-based study exploring the natural history of nevi in periadolescence. (aappublications.org)
  • However, in this study, chronic hypertension was not associated with higher target MAP. (plos.org)
  • This study confirms some risk factors for DSP found in crosssectional studies and suggests a strong relationship between hypertension and DSP. (diabetesjournals.org)
  • Priority will be given to projects with a cross-regional or a comparative area studies focus. (jobs.ac.uk)
  • Prospective comparative study of magnetic resonance imaging. (lww.com)
  • Here, we report the results from a prospective study in northern Sweden, with the aim to estimate the relationship of hyperglycemia, as measured by fasting and postload glucose, with the risk of cancer overall and the risk of cancer at specific organ sites. (diabetesjournals.org)
  • Study record managers: refer to the Data Element Definitions if submitting registration or results information. (clinicaltrials.gov)
  • Let's look at how the problem of regression toward the mean impacts the results of another recently reported prospective study of vitamin D. (vitamindcouncil.org)
  • A paper summarizing results from a five-year prospective study of NDEs conducted in a Welsh hospital in the United Kingdom. (iands.org)
  • The results of these studies are consistent with degeneration of large sensory neurons whereas there was no evidence of distal axonal degeneration even at the lowest toxic doses of cisplatin. (unboundmedicine.com)
  • This study demonstrates that chronic arthralgia is a frequent complication of acute Chikungunya disease and suggests that it results from a local rather than systemic inflammation. (plos.org)
  • As data emerge from clinical trials comparing blood pressure targets for vasopressor therapy, an accurate description of usual care is required to interpret study results. (plos.org)
  • The results of their study were published in the journal PLOS Medicine . (naturalnews.com)
  • 4 , 5 A recent meta-analysis of 51 studies found that ever reporting a sunburn during childhood almost doubled the risk for the development of cutaneous melanoma in adulthood. (aappublications.org)
  • The purpose of our study was to clarify the dose-response association between HDL-C level and risk of total stroke and stroke subtypes by a systematic review and meta-analysis. (cdc.gov)
  • The objective of this study was to assess sunburn and changes in sunburn and sun behaviors during periadolescence. (aappublications.org)
  • The aim of this study is to assess the prevalence of uncontrolled and partly controlled asthma in Italy using a patient-based tool such as Asthma Control Test. (clinicaltrials.gov)
  • This webinar will review a recent study that applied whole-genome sequencing and optical genome mapping to identify a large number of previously undetected somatic structural variants in leukemia samples. (genomeweb.com)
  • There are few prospective epidemiological studies for LBP occupational risk factors and reported data generally have few adjustments for many personal and psychosocial factors. (cdc.gov)
  • Previous studies have investigated psychopathological or psychosocial factors that may be associated with postpartum depression. (nature.com)
  • The Q test and I(2) statistic were used to examine between-study heterogeneity. (nih.gov)
  • Fixed or random effects models were selected based on study heterogeneity. (nih.gov)
  • Mesoscale studies have revealed new understanding of how soil moisture heterogeneity influences the development of convective storms over the course of the diurnal cycle. (hindawi.com)
  • Most studies that investigated the prevalence of postendodontic pain referred to flare-up, which was defined as severe pain and/or swelling after endodontic treatment, requiring an unscheduled appointment and active treatment. (hindawi.com)
  • The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. (clinicaltrials.gov)
  • This study is part of a comprehensive assessment of the validity of FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels in Europe. (naturalnews.com)
  • Welcome, prospective Women's and Gender Studies student! (unl.edu)
  • If you would like to visit SUNY Oswego and take a tour of the Communication Studies facilities, please refer to the schedules listed on the Undergraduate Admissions Office website . (oswego.edu)
  • Durham's Institute of Advanced Study also hosts a number of Fellows every year to explore themes, including those linked to literature, from an interdisciplinary perspective. (dur.ac.uk)
  • This is an interdisciplinary program devoted to the study of women, gender, and sexuality. (unl.edu)
  • Observational studies have shown lymphopenia to be associated with risk of cardiovascular disease, 1 - 5 cancer, 6 - 11 liver disease (including alcohol abuse disorders) 12 , 13 and systemic autoimmune disease. (cmaj.ca)
  • In the comment section of a recent Vitamin D Council review of a study that showed no link between vitamin D and pancreatic cancer , Dr. William Grant pointed out that a major limitation of prospective vitamin D studies is the lag time between the vitamin D measurement and the event of interest. (vitamindcouncil.org)
  • The trial was a prospective, non-randomized case-control study, with a primary endpoint of detecting prostate cancer vs no cancer and a secondary endpoint, differentiating between aggressive and non-aggressive cancer. (businesswire.com)
  • The Shanghai Women's Health Study (SWHS), a collaborative study by NCI, Vanderbilt University, and the Shanghai Cancer Institute, is a prospective cohort study of approximately 75,000 Chinese women who were recruited between 1997 and 2000. (cancer.gov)