Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Risk: The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.Proportional Hazards Models: Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Infant, Newborn: An infant during the first month after birth.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Recurrence: The return of a sign, symptom, or disease after a remission.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Body Mass Index: An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)Odds Ratio: The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Statistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)France: A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris.Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Acute Disease: Disease having a short and relatively severe course.JapanSurvival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Diet: Regular course of eating and drinking adopted by a person or animal.United StatesConfidence Intervals: A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.ROC Curve: A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.Breast Neoplasms: Tumors or cancer of the human BREAST.Postoperative Period: The period following a surgical operation.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Alcohol Drinking: Behaviors associated with the ingesting of alcoholic beverages, including social drinking.Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)Ultrasonography: The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.Epidemiologic Methods: Research techniques that focus on study designs and data gathering methods in human and animal populations.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)C-Reactive Protein: A plasma protein that circulates in increased amounts during inflammation and after tissue damage.Pain Measurement: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.Great BritainAnalysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Gestational Age: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.Vegetables: A food group comprised of EDIBLE PLANTS or their parts.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Pilot Projects: Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.NorwayAge Distribution: The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Biopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Ultrasonography, Doppler, Color: Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.SwedenIndiaPostmenopause: The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.ParisHospitalization: The confinement of a patient in a hospital.Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.Linear Models: Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Length of Stay: The period of confinement of a patient to a hospital or other health facility.Coffee: A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.Pregnancy Outcome: Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Stress, Psychological: Stress wherein emotional factors predominate.Ultrasonography, Prenatal: The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.DenmarkPain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Obesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Endoscopy: Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Recovery of Function: A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.Reference Values: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.Depression: Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Zollinger-Ellison Syndrome: A syndrome that is characterized by the triad of severe PEPTIC ULCER, hypersecretion of GASTRIC ACID, and GASTRIN-producing tumors of the PANCREAS or other tissue (GASTRINOMA). This syndrome may be sporadic or be associated with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1.China: A country spanning from central Asia to the Pacific Ocean.Anthropometry: The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.Athletic Injuries: Injuries incurred during participation in competitive or non-competitive sports.Abdomen: That portion of the body that lies between the THORAX and the PELVIS.EnglandProbability: The study of chance processes or the relative frequency characterizing a chance process.Fruit: The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.Radiopharmaceuticals: Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)Postoperative Care: The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)Confounding Factors (Epidemiology): Factors that can cause or prevent the outcome of interest, are not intermediate variables, and are not associated with the factor(s) under investigation. They give rise to situations in which the effects of two processes are not separated, or the contribution of causal factors cannot be separated, or the measure of the effect of exposure or risk is distorted because of its association with other factors influencing the outcome of the study.Blood Sedimentation: Measurement of rate of settling of erythrocytes in anticoagulated blood.Patient Satisfaction: The degree to which the individual regards the health care service or product or the manner in which it is delivered by the provider as useful, effective, or beneficial.Lumbar Vertebrae: VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.FinlandAnti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Nurses: Professionals qualified by graduation from an accredited school of nursing and by passage of a national licensing examination to practice nursing. They provide services to patients requiring assistance in recovering or maintaining their physical or mental health.Ultrasonography, Doppler: Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Life Style: Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)Parity: The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Occupational Diseases: Diseases caused by factors involved in one's employment.Netherlands: Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, Sint Maarten, formerly included in the NETHERLANDS ANTILLES.Fractures, Bone: Breaks in bones.Lung Neoplasms: Tumors or cancer of the LUNG.Kaplan-Meier Estimate: A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)Pregnancy Complications: Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Patient Selection: Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.Combined Modality Therapy: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.Fluorodeoxyglucose F18: The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.Pregnancy Trimester, First: The beginning third of a human PREGNANCY, from the first day of the last normal menstrual period (MENSTRUATION) through the completion of 14 weeks (98 days) of gestation.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Bacterial Infections: Infections by bacteria, general or unspecified.Surgical Wound Infection: Infection occurring at the site of a surgical incision.Prostatic Neoplasms: Tumors or cancer of the PROSTATE.Observer Variation: The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Intensive Care Units: Hospital units providing continuous surveillance and care to acutely ill patients.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Kidney Transplantation: The transference of a kidney from one human or animal to another.Anxiety: Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.Evaluation Studies as Topic: Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.Outcome Assessment (Health Care): Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).HIV Infections: Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).Ultrasonography, Doppler, Duplex: Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.Health Status: The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.GermanyFood Habits: Acquired or learned food preferences.Nutritional Status: State of the body in relation to the consumption and utilization of nutrients.Neurologic Examination: Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Decompression, Surgical: A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)Blood Glucose: Glucose in blood.Dairy Products: Raw and processed or manufactured milk and milk-derived products. These are usually from cows (bovine) but are also from goats, sheep, reindeer, and water buffalo.Hong Kong: The former British crown colony located off the southeast coast of China, comprised of Hong Kong Island, Kowloon Peninsula, and New Territories. The three sites were ceded to the British by the Chinese respectively in 1841, 1860, and 1898. Hong Kong reverted to China in July 1997. The name represents the Cantonese pronunciation of the Chinese xianggang, fragrant port, from xiang, perfume and gang, port or harbor, with reference to its currents sweetened by fresh water from a river west of it.Spain: Parliamentary democracy located between France on the northeast and Portugual on the west and bordered by the Atlantic Ocean and the Mediterranean Sea.CreatinineMorbidity: The proportion of patients with a particular disease during a given year per given unit of population.Disability Evaluation: Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.Fertilization in Vitro: An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.Visual Acuity: Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.Radius FracturesPolymyalgia Rheumatica: A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.Weight Gain: Increase in BODY WEIGHT over existing weight.Referral and Consultation: The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.Intraoperative Period: The period during a surgical operation.ItalyTreatment Failure: A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.Patient Compliance: Voluntary cooperation of the patient in following a prescribed regimen.ScotlandBrazilPsychiatric Status Rating Scales: Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.Mortality: All deaths reported in a given population.Mass Screening: Organized periodic procedures performed on large groups of people for the purpose of detecting disease.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Trauma Severity Indices: Systems for assessing, classifying, and coding injuries. These systems are used in medical records, surveillance systems, and state and national registries to aid in the collection and reporting of trauma.Pregnancy Rate: The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.Sick Leave: An absence from work permitted because of illness or the number of days per year for which an employer agrees to pay employees who are sick. (Webster's New Collegiate Dictionary, 1981)Liver Neoplasms: Tumors or cancer of the LIVER.Pain, Postoperative: Pain during the period after surgery.Injury Severity Score: An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.Nurses' Aides: Allied health personnel who assist the professional nurse in routine duties.Diet Surveys: Systematic collections of factual data pertaining to the diet of a human population within a given geographic area.Hospitals, University: Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.IowaBody Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Body Height: The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.Accidental Falls: Falls due to slipping or tripping which may result in injury.Range of Motion, Articular: The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.Activities of Daily Living: The performance of the basic activities of self care, such as dressing, ambulation, or eating.Disease-Free Survival: Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.False Positive Reactions: Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)Monitoring, Intraoperative: The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).

Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. (1/70469)

BACKGROUND: Since 1968 it has been known that bone marrow transplantation can ameliorate severe combined immunodeficiency, but data on the long-term efficacy of this treatment are limited. We prospectively studied immunologic function in 89 consecutive infants with severe combined immunodeficiency who received hematopoietic stem-cell transplants at Duke University Medical Center between May 1982 and September 1998. METHODS: Serum immunoglobulin levels and lymphocyte phenotypes and function were assessed and genetic analyses performed according to standard methods. Bone marrow was depleted of T cells by agglutination with soybean lectin and by sheep-erythrocyte rosetting before transplantation. RESULTS: Seventy-seven of the infants received T-cell-depleted, HLA-haploidentical parental marrow, and 12 received HLA-identical marrow from a related donor; 3 of the recipients of haploidentical marrow also received placental-blood transplants from unrelated donors. Except for two patients who received placental blood, none of the recipients received chemotherapy before transplantation or prophylaxis against graft-versus-host disease. Of the 89 infants, 72 (81 percent) were still alive 3 months to 16.5 years after transplantation, including all of the 12 who received HLA-identical marrow, 60 of the 77 (78 percent) who were given haploidentical marrow, and 2 of the 3 (67 percent) who received both haploidentical marrow and placental blood. T-cell function became normal within two weeks after transplantation in the patients who received unfractionated HLA-identical marrow but usually not until three to four months after transplantation in those who received T-cell-depleted marrow. At the time of the most recent evaluation, all but 4 of the 72 survivors had normal T-cell function, and all the T cells in their blood were of donor origin. B-cell function remained abnormal in many of the recipients of haploidentical marrow. In 26 children (5 recipients of HLA-identical marrow and 21 recipients of haploidentical marrow) between 2 percent and 100 percent of B cells were of donor origin. Forty-five of the 72 children were receiving intravenous immune globulin. CONCLUSIONS: Transplantation of marrow from a related donor is a life-saving and life-sustaining treatment for patients with any type of severe combined immunodeficiency, even when there is no HLA-identical donor.  (+info)

Chemokine mRNA expression in gastric mucosa is associated with Helicobacter pylori cagA positivity and severity of gastritis. (2/70469)

AIM: To investigate the association between the quantity of gastric chemokine mRNA expression, severity of gastritis, and cagA positivity in Helicobacter pylori associated gastritis. METHODS: In 83 dyspeptic patients, antral and corpus biopsies were taken for semiquantitative reverse transcription polymerase chain reaction (RT-PCR) and histological grading of gastritis. Gastritis was evaluated by visual analogue scales. Quantities of chemokine (IL-8, GRO alpha, ENA-78, RANTES, MCP-1) RT-PCR products were compared with G3PDH products. Each sample was also evaluated for the presence of cagA and ureA mRNA by RT-PCR. RESULTS: mRNA expression of all five chemokines was significantly greater in H pylori positive than in H pylori negative mucosa. In H pylori positive patients, in the antrum C-X-C chemokine mRNA expression was significantly greater in cagA positive patients than in cagA negative patients, but there were no significant differences in C-C chemokine mRNA expression. In H pylori positive patients, chemokine mRNA expression in the corpus was less than in the antrum. In contrast to the antrum, only GRO alpha mRNA expression was significantly greater in cagA positive infection. Polymorphonuclear cell infiltration was correlated with C-X-C chemokine mRNA expression. Significant correlations were also found between bacterial density and C-X-C chemokine mRNA expression. CONCLUSIONS: In H pylori infection, C-X-C chemokines may play a primary role in active gastritis. Infection with cagA positive H pylori induces greater gastric chemokine mRNA expression in the antral mucosa, which may be relevant to the increased mucosal damage associated with cagA positive H pylori infection.  (+info)

Reproductive factors and fatal hip fractures. A Norwegian prospective study of 63,000 women. (3/70469)

STUDY OBJECTIVE: The aim of the study was to investigate the impact of reproductive variables (age at menarche, menopause, first and last birth as well as parity, lactation, and abortions) on hip fracture mortality. DESIGN AND SETTING: A prospective study in Norway with more than 60,000 women followed up for 29 years. A total of 465 deaths as a result of hip fracture were recorded. MAIN RESULTS: Statistically significant linear relations (p < or = 0.02) were found between both age at menarche and length of reproductive period (defined as age at menopause to age at menarche) and the mortality of hip fractures in women aged less than 80. The death rate for women with a late menarche (> or = 17 years) was twice that of the women with relatively early menarche (< or = 13 years). Compared with women with less than 30 years between menopause and menarche, the mortality rate ratio in women with more than 38 reproductive years was 0.5. We also found an inverse relation with age at first birth. CONCLUSIONS: This study supports by hypothesis that an early menarche and a long reproductive period protect against hip fracture mortality. High age at first birth may also be protective.  (+info)

Postoperative tetany in Graves disease: important role of vitamin D metabolites. (4/70469)

OBJECTIVE: To test the authors' hypothesis of the causal mechanism(s) of postoperative tetany in patients with Graves disease. SUMMARY BACKGROUND DATA: Previous studies by the authors suggested that postoperative tetany in patients with Graves disease occurs during the period of bone restoration and resulted from continuation of a calcium flux into bone concomitant with transient hypoparathyroidism induced by surgery. PATIENTS AND METHODS: A prospective study was carried out to investigate sequential changes in serum levels of intact parathyroid hormone (iPTH), calcium and other electrolytes, 25-hydroxyvitamin D (25OHD), 1,25-dihydroxyvitamin D (1,25(OH)2D), and bone metabolic markers in 109 consecutive patients with Graves disease who underwent subtotal thyroidectomy. RESULTS: Preoperative serum iPTH levels negatively correlated with ionized calcium levels and positively correlated with 1,25(OH)2D or 1,25(OH)2D/25OHD. After the operation, there was a significant decline in levels of ionized calcium, magnesium, and iPTH. Serum iPTH was not detected in 15 patients after surgery. Four of these 15 patients, and 1 patient whose iPTH level was below normal, developed tetany. Preoperative serum ionized calcium levels were significantly lower, and iPTH levels were higher, in the 5 patients with tetany than in the 11 patients who did not develop tetany despite undetectable iPTH levels. The tetany group had significantly lower serum 25OHD levels and higher 1,25(OH)2D levels, and had increased 1,25(OH)2D/25OHD as an index of the renal 25OHD-1-hydroxylase activity than those in the nontetany group. These results suggest that patients with a high serum level of iPTH as a result of low serum calcium levels (secondary hyperparathyroidism) are susceptible to tetany under conditions of hypoparathyroid function after surgery. CONCLUSIONS: Postoperative tetany occurs in patients with secondary hyperparathyroidism caused by a relative deficiency in calcium and vitamin D because of their increased demand for bone restoration after preoperative medical therapy concomitant with transient hypoparathyroidism after surgery. Calcium and vitamin D supplements may be recommended before and/or after surgery for patients in whom postoperative tetany is expected to develop.  (+info)

HLA-DR expression and soluble HLA-DR levels in septic patients after trauma. (5/70469)

OBJECTIVE: To determine if cellular and soluble HLA-DR molecules may be relevant in severely injured patients for the development of gram-positive or gram-negative sepsis. SUMMARY BACKGROUND DATA: HLA-DR molecules play a central role in the specific immune response to infection. The reduced HLA-DR expression on monocytes is considered to correlate with infectious complications and the development of sepsis. Data on the role of HLA-DR expression on T cells and soluble HLA-DR molecules are rare. METHODS: HLA-DR expression on monocytes and T cells was measured by flow cytometry. Plasma levels of soluble HLA-DR were studied by enzyme-linked immunosorbent assay. RESULTS: HLA-DR expression on circulating T cells, calculated as mean fluorescence intensity in channels, was reduced at day 1 after admission in 20 patients with subsequent severe sepsis compared with 46 patients without sepsis. The septic patients immediately after trauma had significantly lower soluble HLA-DR plasma levels than the nonseptic patients. At day 2 after admission, HLA-DR expression on monocytes was significantly lower in the severe sepsis group than in the patients without sepsis, and lasted until day 14 after injury. CONCLUSIONS: In severely injured patients, decreased levels of cellular and soluble HLA-DR appear as early indicators of an immune deviation associated with the development of severe sepsis. Moreover, immune alterations of different cell types may promote distinct kinds of septicemia.  (+info)

Serum triglyceride: a possible risk factor for ruptured abdominal aortic aneurysm. (6/70469)

BACKGROUND: We aimed to determine the relationship between ruptured abdominal aortic aneurysm (AAA) and serum concentrations of lipids and apolipoproteins. METHODS: A cohort of 21 520 men, aged 35-64 years, was recruited from men attending the British United Provident Association (BUPA) clinic in London for a routine medical examination in 1975-1982. Smoking habits, weight, height and blood pressure were recorded at entry. Lipids and apolipoproteins were measured in stored serum samples from the 30 men who subsequently died of ruptured AAA and 150 matched controls. RESULTS: Triglyceride was strongly related to risk of ruptured AAA. In univariate analyses the risk in men on the 90th centile of the distribution relative to the risk in men on the 10th (RO10-90) was 12 (95% confidence interval [CI] : 3.8-37) for triglyceride, 5.5 (95% CI: 1.8-17) for apolipoprotein B (apoB) (the protein component of low density lipoprotein [LDL]), 0.15 (95% CI : 0.04-0.56) for apo A1 (the protein component of high density lipoprotein [HDL]), 3.7 (95% CI: 1.4-9.4) for body mass index and 3.0 (95% CI: 1.1-8.5) for systolic blood pressure. Lipoprotein (a) (Lp(a)) was not a significant risk factor (RO10-90 = 1.6, 95% CI: 0.6-3.0). In multivariate analysis triglyceride retained its strong association. CONCLUSION: Triglyceride appears to be a strong risk factor for ruptured AAA, although further studies are required to clarify this. If this and other associations are cause and effect, then changing the distribution of risk factors in the population (by many people stopping smoking and adopting a lower saturated fat diet and by lowering blood pressure) could achieve an important reduction in mortality from ruptured AAA.  (+info)

Respiratory symptoms and long-term risk of death from cardiovascular disease, cancer and other causes in Swedish men. (7/70469)

BACKGROUND: Depressed respiratory function and respiratory symptoms are associated with impaired survival. The present study was undertaken to assess the relation between respiratory symptoms and mortality from cardiovascular causes, cancer and all causes in a large population of middle-aged men. METHODS: Prospective population study of 6442 men aged 51-59 at baseline, free of clinical angina pectoris and prior myocardial infarction. RESULTS: During 16 years there were 1804 deaths (786 from cardiovascular disease, 608 from cancer, 103 from pulmonary disease and 307 from any other cause). Men with effort-related breathlessness had increased risk of dying from all of the examined diseases. After adjustment for age, smoking habit and other risk factors, the relative risk (RR) associated with breathlessness of dying from coronary disease was 1.43 (95% CI : 1.16-1.77), from stroke 1.77 (95% CI: 1.07-2.93), from any cardiovascular disease 1.48 (95% CI : 1.24-1.76), cancer 1.36 (95% CI : 1.11-1.67) and from any cause 1.62 (95% CI: 1.44-1.81). An independent effect of breathlessness on cardiovascular death, cancer death and mortality from all causes was found in life-time non-smokers, and also if men with chest pain not considered to be angina were excluded. An independent effect was also found if all deaths during the first half of the follow-up were excluded. Men with cough and phlegm, without breathlessness, also had an elevated risk of dying from cardiovascular disease and cancer, but after adjustment for smoking and other risk factors this was no longer significant. However, a slightly elevated independent risk of dying from any cause was found (RR = 1.18 [95% CI: 1.02-1.36]). CONCLUSION: A positive response to a simple question about effort related breathlessness predicted subsequent mortality from several causes during a follow-up period of 16 years, independently of smoking and other risk factors.  (+info)

Cardiovascular disease in insulin dependent diabetes mellitus: similar rates but different risk factors in the US compared with Europe. (8/70469)

BACKGROUND: Cardiovascular disease (CVD) in insulin dependent diabetes mellitus (IDDM) has been linked to renal disease. However, little is known concerning international variation in the correlations with hyperglycaemia and standard CVD risk factors. METHODS: A cross-sectional comparison was made of prevalence rates and risk factor associations in two large studies of IDDM subjects: the Pittsburgh Epidemiology of Diabetes Complications Study (EDC) and the EURODIAB IDDM Complications Study from 31 centres in Europe. Subgroups of each were chosen to be comparable by age and duration of diabetes. The EDC population comprises 286 men (mean duration 20.1 years) and 281 women (mean duration 19.9 years); EURODIAB 608 men (mean duration 18.1 years) and 607 women (mean duration 18.9 years). The mean age of both populations was 28 years. Cardiovascular disease was defined by a past medical history of myocardial infarction, angina, and/or the Minnesota ECG codes (1.1-1.3, 4.1-4.3, 5.1-5.3, 7.1). RESULTS: Overall prevalence of CVD was similar in the two populations (i.e. men 8.6% versus 8.0%, women 7.4% versus 8.5%, EURODIAB versus EDC respectively), although EDC women had a higher prevalence of angina (3.9% versus 0.5%, P < 0.001). Multivariate modelling suggests that glycaemic control (HbA1c) is not related to CVD in men. Age and high density lipoprotein cholesterol predict CVD in EURODIAB, while triglycerides and hypertension predict CVD in EDC. For women in both populations, age and hypertension (or renal disease) are independent predictors. HbA1c is also an independent predictor-inversely in EURODIAB women (P < 0.008) and positively in EDC women (P = 0.03). Renal disease was more strongly linked to CVD in EDC than in EURODIAB. CONCLUSIONS: Despite a similar prevalence of CVD, risk factor associations appear to differ in the two study populations. Glycaemic control (HbA1c) does not show a consistent or strong relationship to CVD.  (+info)

TY - JOUR. T1 - A multicenter prospective cohort study to develop frailty-based prognostic criteria in heart failure patients (FLAGSHIP). T2 - Rationale and design. AU - on behalf of the FLAGSHIP collaborators. AU - Yamada, Sumio. AU - Adachi, Takuji. AU - Izawa, Hideo. AU - Izawa, Hideo. AU - Kondo, Takaaki. PY - 2018/8/2. Y1 - 2018/8/2. N2 - Background: Heart failure (HF) and frailty often co-exist, and frailty in HF results in a poor prognosis. However, in Asian populations, prognostic criteria are needed to examine the effect of frailty on HF. Therefore, we conducted a nationwide cohort study to develop frailty-based prognostic criteria in HF patients (FLAGSHIP). FLAGSHIP mainly aims to 1) develop the frailty criteria based on HF-specific outcomes, 2) propose a hypothesis of the potential mechanisms of frailty manifestations in HF, and 3) examine the effects of outpatient cardiac rehabilitation on frailty. Methods: In this prospective study, we consecutively enroll ambulatory patients ...
Observational Prospective Study to Evaluate AEs, Risk Factors and Drug Utilization of BUSCAPINA COMPOSITUM N in Adults From Metropolitan Lima
Pap screening, an effective method for cervical cancer prevention, is now supported by molecular human papillomavirus (HPV) testing. Recently commercialised preventive vaccines also provide new tools for the primary prevention of cervical cancer. To determine appropriate prevention strategies, the Health General Direction, Lombardy Region, funded a project that aims to characterize and monitor HPV infections and related cervical diseases in high-risk women.
Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Background and purpose: About 20% of patients with acute ischemic stroke experience symptom progression resulting in poor outcome. We have evaluated the effect of cilostazol compared with aspirin on preventing acute symptom progression, and on clinical outcome.. Methods: A multi-center, open, randomized, prospective comparative study conducted from April 2009 to March 2011. Inclusion criteria: non-cardioembolic ischemic stroke admitted within 48 hours of onset, neurologically stable, and with written informed consent. Exclusion criteria: contraindicated or previous exposure to aspirin and/or cilostazol. Patients were administered either cilostazol 200 mg daily (group C) or aspirin 200 mg daily (group A) within 48 hours of onset. Primary endpoint: occurrence of acute symptom progression (ΔNIHSS ≥2) within 7 days. Secondary endpoints: 3-month outcome (mRS 0-2), occurrence of vascular events (ischemic stroke, brain hemorrhage, myocardial infarction), bleeding events, and other adverse events. ...
Methods Prospective data on 204 lactating mothers of a healthy term singleton infant (normal pregnancy, labor and delivery) on day 2 after delivery. Exclusion: preterm and postterm infants, maternal treatment with antidepressant, anticonvulsants, or magnesium sulfate, previous breast surgery, opiates for analgesia; infants with major congenital malformations, or neonatal complications. Anthropometrics included: inter-nipple distance, nipple length, and horizontal and vertical diameters; cup size (best fit to a lactation bras); infant goniomaxillary length/gonio-mandibular length (GMxL/GMnL) ratio and intercommissural distance. A latch score was performed after measurements. Data collected included gravidity, parity, gestational age, previous breast feeding experience, and early breast feeding (,2 hours after delivery). Backward stepwise regression analysis was used to study the combined effect of several independent variables upon latch score. ...
Multigenic approaches have been demonstrated to be valid tools for identifying subjects at risk for complex traits, such as type 2 diabetes (17) and coronary artery disease (18). A similar strategy was used in the present study, hypothesizing that, in subjects with type 2 diabetes, an increasing number of proinflammatory alleles may confer a significant risk of developing ischemic stroke. We have previously demonstrated the utility of the Go-DARTS cohort to study the contribution of gene variations to cardiovascular risk in subjects with diabetes (14-16). To our knowledge, this is the first prospective study that attempts to look at the impact of the combined effect of multiple gene variations on incident stroke. It is also the first prospective study considering the combination of multiple inflammatory SNPs in diabetic individuals.. The decision to study the rs1800795, rs5498, rs5361, rs1024611, and rs679620 of the IL-6, MCP-1, ICAM-1, sel-E, and MMP-3 genes was based on the following criteria. ...
Objective-To examine the relation between resting heart rate and new major ischaemic heart disease events in middle aged men with and without pre-existing ischaemic heart disease. Design-Prospective study of a cohort of men with eight years follow up for cardiovascular morbidity and mortality for all men. Setting-General practices in 24 British...
Tolerability of Shortened Infliximab Infusion in Scheduled Maintenance Therapy for IBD: a Prospective Multi-center European Cohort Study
To analyze the impact of multimorbidity (MM) on health care costs taking into account data heterogeneity. Data come from a multicenter prospective cohort study of 1,050 randomly selected primary care patients aged 65 to 85 years suffering from MM in Germany. MM was defined as co-occurrence of ≥3 conditions from a list of 29 chronic diseases. A conditional inference tree (CTREE) algorithm was used to detect the underlying structure and most influential variables on costs of inpatient care, outpatient care, medications as well as formal and informal nursing care. Irrespective of the number and combination of co-morbidities, a limited number of factors influential on costs were detected. Parkinsons disease (PD) and cardiac insufficiency (CI) were the most influential variables for total costs. Compared to patients not suffering from any of the two conditions, PD increases predicted mean total costs 3.5-fold to approximately € 11,000 per 6 months, and CI two-fold to approximately € 6,100. The high
To analyze the impact of multimorbidity (MM) on health care costs taking into account data heterogeneity. Data come from a multicenter prospective cohort study of 1,050 randomly selected primary care patients aged 65 to 85 years suffering from MM in Germany. MM was defined as co-occurrence of ≥3 conditions from a list of 29 chronic diseases. A conditional inference tree (CTREE) algorithm was used to detect the underlying structure and most influential variables on costs of inpatient care, outpatient care, medications as well as formal and informal nursing care. Irrespective of the number and combination of co-morbidities, a limited number of factors influential on costs were detected. Parkinsons disease (PD) and cardiac insufficiency (CI) were the most influential variables for total costs. Compared to patients not suffering from any of the two conditions, PD increases predicted mean total costs 3.5-fold to approximately € 11,000 per 6 months, and CI two-fold to approximately € 6,100. The high
Supplementary MaterialsSupplementary materials 1 (DOCX 637 KB) 392_2019_1424_MOESM1_ESM. not analyzed. The medial and lateral plots and by the KolmogorovCSmirnov test. Normally and non-Gaussian distributed variables were reported as mean (SD) or median (interquartile range), respectively. All biomarker levels were log10 transformed and normalised to 1 1 SD increment. Normalised data were analysed using ANOVA and general linear models, and values were Bonferroni-corrected for multiple comparisons. Non-Gaussian data and categorical variables were analysed using non-parametric tests [MannCWhitney test, KruskalCWallis test and Spearman (value(%) and imply (SD) or median (Interquartile range) are reported. beliefs are quoted for the ANOVA/Kruskal Chi or Wallis squared exams for constant or categorical factors, respectively angiotensin 2 receptor blocker Relationship evaluation PENK was correlated to age group (rating of log natriuretic peptides (0.437, nonsignificant). Open up in another home window ...
In the frame of multicenter research studies, biobanks ensure the harmonization and traceability of the prospective collection of quality samples. This is significant because pre-analytical variables must be carefully considered to guarantee the integrity of biomarkers to be tested and to avoid bias affecting the validity of the analytical results. According to a quality management system, biobanks contribute with documents and records; consumable preparation for collection, processing, and conservation; sample quality controls; and centralized management of sample handling, storage, and distribution. Traceability of samples is based on unique standard codes and the use of pre-assigned, pre-coded, and pre-labeled materials for sample collection, processing, and conservation. By using these supporting tools, quality derivatives are obtained based on common and evidence-based standard operating procedures (SOPs), with associated traceability information in relation with their collection, processing,
Langdorf MI, Medak AJ, Hendey GW, Nishijima DK, Mower WR, Raja AS, Baumann BM, Anglin DR, Anderson CL, Lotfipour S, Reed KE, Zuabi N, Khan NA, Bithell CA, Rowther AA, Villar J, Rodriguez RM. Prevalence and Clinical Import of Thoracic Injury Identified by Chest Computed Tomography but Not Chest Radiography in Blunt Trauma: Multicenter Prospective Cohort Study. Ann Emerg Med. 2015 Dec;66(6):589-600. doi: 10.1016/j.annemergmed.2015.06.003. Epub 2015 Jul 11. PubMed PMID: 26169926 ...
OBJECTIVE--To examine the associations between air temperature and risk factors for ischaemic heart disease. METHOD--Data on risk factors are available from up to 2036 men in the Caerphilly Prospective Heart Disease Study. Daily temperatures were obtained from the Meteorological Office. Relations between these were examined by regression. RESULTS--The coldest month of the year has a mean temperature that is 16 degrees C lower than that in the warmest month. A fall in temperature of this magnitude is associated with higher blood pressures (by 3-5 mm Hg) and a lower concentration of high density lipoprotein cholesterol (by 0.08 mmol/l). The most important effects however, seem to be on the haemostatic system. Fibrinogen is 0.34 g/l higher in the coldest month than in the warmest (p , 0.001) and alpha 2 macroglobulin, a protein that inhibits fibrinolysis, is also raised. Platelet count is increased by 30% of a standard deviation and the sensitivity of platelets in whole blood to adenosine ...
To determine the time course of development of resistance to atevirdine mesylate ( U-87201E ) in patients with HIV isolates showing in vitro resistance to zidovudine ( AZT ). To determine the genotype changes in HIV reverse transcriptase associated with in vitro AZT resistance to U-87201E. To determine the genotype and phenotype effects of treatment with a nondideoxynucleoside agent on the alterations of the HIV-1 population associated with in vitro AZT resistance. To determine whether serial passage of patient pre-drug HIV isolates in the presence of U-87201E will generate the resistant mutants that may subsequently emerge in the patients ...
This page contains the abstract Morbidity and Mortality of Major Adult Spinal Surgery. A Prospective Cohort Analysis of 942 Consecutive Patients http://www.chiro.org/LINKS/ABSTRACTS/Morbidity_and_Mortality_of_Major_Adult.shtml
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Nicotine dependence in a prospective population-based study of adolescents: the protective role of a functional tyrosine hydroxylase polymorphism Journal Articles Refereed ...
This study is the first to document the population incidence in the UK of SUPC in infants who were assessed as being healthy at birth. The incidence (0.05/1000 term live births) is consistent with case, regional and national series, suggesting an incidence ranging from between 0.026/1000 live births in the first 24 h of birth10 to 0.27/1000 where collapse occurs within 3 days of birth.2 The overall BPSU respondent rate (94.6% for 2008) is higher than any equivalent UK scheme and ranks highly against other national paediatric surveillance units. However, complete ascertainment of all cases of SUPC occurring within the study period could not be verified. This was due to the complexity of the case definition and the heterogeneity that exists in the classification of such infant deaths, which precluded cross-checking against national and regional databases. As such, the incidence in this study may be an underestimate.. One third of infants had an underlying condition leading to collapse and a ...
Background Multiple Sclerosis (MS) is the most common cause of neurological disability in young and middle-aged adults. At this stage in life most people are in the midst of their working career. The...
Context: Despite the frequent occurrence of depressive symptoms among older adults, especially women, little is known about the long-term course of late-life depressive symptoms. Objective: To characterize the natural course of depressive symptoms among older women (from the young old to the oldest old) followed up for almost 20 years. Design: Using latent-class growth-curve analysis, we analyzed women enrolled in an ongoing prospective cohort study (1988 through 2009). Setting: Clinic sites in Baltimore, Maryland; Minneapolis, Minnesota; the Monongahela Valley near Pittsburgh, Pennsylvania; and Portland, Oregon. Participants: We studied 7240 community-dwelling women 65 years or older. Main Outcome Measure: The Geriatric Depression Scale short form (score range, 0-15) was used to routinely assess depressive symptoms during the follow-up period. Results: Among older women, we identified 4 latent classes during 20 years, with the predicted probabilities of group membership totaling 27.8% with ...
This study represents the largest prospective series of febrile children returning from the tropics. We have identified a high proportion of treatable conditions, and highlighted the importance of common cosmopolitan infections as well as exotic illnesses presenting with fever in this population. The majority of diagnoses requiring medical treatment were made using simple investigations.. Previous studies of imported infections have concentrated on adult travellers presenting to tertiary centres,6 often returning from Sub-Saharan Africa.4,5 Our study population, being largely South Asian, is therefore very different. Most imported malaria from the Indian subcontinent is caused by Plasmodium vivax, as in our study.9 Only 30% of children with this type of malaria present within a month of return.9 Imported malaria from Africa is mostly P falciparum, a potentially life threatening infection. This mostly presents within one month of return.9. Many new arrivals from Africa will stay in the South East ...
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The majority of youth with type 1 diabetes are above hemoglobin A1c (HbA1c) targets. Continuous glucose monitoring (CGM) has been shown to improve clinical outcomes, and use early in the course of diabetes has the potential to improve glycemic outcomes and improve quality of life.. In our clinic, youth with new-onset type 1 diabetes were offered the opportunity to start on CGM (Dexcom G6) soon after diabetes diagnosis. Ongoing CGM coverage was subsequently applied for through the patients insurance. Following CGM initiation, youth had a 1-week follow-up with a nurse practitioner. Per clinic standard of care, youth were seen again at 1 month post-diagnosis and every 3 months thereafter. We prospectively collected data on HbA1c, continued CGM use, days of CGM wear, method of viewing CGM data, time in range (TIR), and time in hypoglycemia. Institutional review board approval was obtained for the prospective data collection.. From July 2018 to April 2019, we approached 44 youth with newly diagnosed ...
Data presented as median (interquartile range). P value by Kruskall-Wallis. Intergroup differences by Mann Whitney. +P value significantly higher in fentanyl group compared to morphine group (p,0.05). N.S=Non Significant ...
Following this initial letter, two subsequent case series have been published supporting the peripheral-IJ as a reasonable alternative for temporary venous access. The first case series of 9 patients placed them in patients with unobtainable IV access [2]. 64 mm angiocatheters were used to cannulate the IJ under ultrasound guidance using the above-described technique. All catheters were labeled for removal within 72 hrs. All patients were followed up via chart review one year later. Two of 9 catheters failed due to kinking within the first 48 hrs. There were no apparent adverse outcomes in any patient including deep vein thrombosis, bacteremia, endocarditis or pneumothorax. A second group conducted a prospective case series in which 9 patients underwent placement of a peripheral IJ" (PIJ), when other access could not be obtained and the patient did not initially require a central line [3]. The authors attempted follow-up with all patients within a week. On follow-up, the seven patients who ...
It was the objective of this study to document and evaluate AZT-induced short-term toxicity in healthy individuals. The study was designed as a longitudinal monocentric side-effect monitoring study with prospective data collection. It was carried out at the Cologne University Hospital. The study population comprised health care workers who were...
The concept of exclusive breastfeeding in relation to daily feeding practices and to health and growth of infants in an affluent society was examined. In a descriptive longitudinal prospective study 506 mother-infant pairs were followed from birth through the greater part of the first year. Feeding was recorded daily, and health and growth were recorded fortnightly. Large individual variations were seen in breastfeeding patterns. A wide discrepancy between the exclusive breastfeeding rates obtained from "current status" data and data "since birth" was found.. Using a strict definition of exclusive breastfeeding from birth and taking into account the reasons for giving complementary feeding, the study showed that many exclusively breastfed infants had infections early in life, the incidence of which increased with age, despite continuation of exclusive breastfeeding. However, truly exclusively breastfed infants seem less likely to suffer infections than infants who receive formula in addition to ...
This article explains a prospective study at an academic hospital studying adverse events in 400 consecutive patients after discharge from a medical service. The authors describe the incidence, severity, and preventability of reported events along with specific examples captured during the study. They discuss strategies to improve patient safety by emphasizing the vulnerability of the discharge transition from hospital to home.
Population-based disease registry systems are invaluable research resources due to their non-biased coverage, prospective data collection, large size, and length of follow up.
Université de Liège - ULiège , Département des sciences de la santé publique , Santé publique, Epidémiologie et Economie de la santé ,] ...
Results: Cross-sectional associations between optimism and each of the study outcomes were strongly protective but tended to differ according to gender in extent. In prospective analyses of the onset of new cases of each study outcome, protective associations were weaker. Those in the highest optimism quartile had risks for depressive symptoms that were reduced by almost half (odds ratio: 0.54 [95% confidence interval: 0.42-0.70]) compared with those in the lowest category. No effect was seen in prevention of anxiety symptoms after adjustment for other aspects of psychological style. In predicting the onset of heavy substance use and antisocial behavior, high optimism had modest protective effects. ...
Data centres have become a critical piece of technological infrastructure in todays information age. Any business or organization that manages a large volume of information can benefit from operating a well-structured data centre. Data centres are facilities in which networked computers, storage, and hardware work together to manage large sums of data. Data centres have ...
Question: I am on the down side of my 50s and have been struggling not only to push myself to exercise but once I get there my joints hurt for the first half
The president-elect and his wife have arrived in Washington, D.C. ahead of Fridays Inauguration. The Trumps touched down Thursday afternoon at Andrews Airforce Base inside a military jet. Now, the soon-to-be first daughter Ivanka Trump is speaking out ov
In 2012 the law changed. Deposits taken by residential landlords must now be handed over to one of three government-approved Tenancy Deposit Schemes within 30 days of the start of the tenancy.
Security for Future Networks : a Prospective Study of AAIs Hassane Aissaoui, Pascal Urien, Guy Pujolle, Fraga Joni da Silva, Böger Davi da Silva To cite this version: Hassane Aissaoui, Pascal Urien, Guy
Kling and his family arrived at the hospital at 7:30 a.m. He was then prepped and waiting in the pre-operating room as surgeon Dr. Jim Maloney examined the lung for any possible complications. Once he deemed it safe to proceed, the rest moved quickly.. Steve Kling looks out over his farm after returning to his home on January 13. Unable to complete barn chores on his own, he is hopeful he will find a young couple to help transition ownership of the herd.. "It was just like a scene from the movies," Kling said. "The surgeon came out and said, Its a go. It was time for hugs and kisses and they were taking me back.". The surgery went smoothly and by 7:30 p.m., Kling was awake. He said it was nothing short of amazing.. "It really felt like a dream. During the surgery, I was on a breathing machine. Once they took out the tube, I was breathing on my own. I didnt need oxygen anymore," Kling said.. Kling spent nine days in the hospital and another eight in a hotel nearby. During this time, Kling was ...
Two techniques have been utilized to make sure higher precision of the results. The data have been 1st manually transferred to standardized forms, then double
Visit the French Mediterranean and enjoy a tranquil day looking out over the sea at some of the clearest and most vivid skies you will find anywhere in the world.
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OBJECTIVES--To assess the relationship between haematocrit and risk of major ischaemic heart disease events. DESIGN--Prospective study of a cohort of men followed up for 9.5 years. SETTING--General practices in 24 towns in England, Wales, and Scotland (British Regional Heart Study). SUBJECTS--Altogether 7735 men aged 40-59 years at screening, who were selected at random from one general practice in each of 24 towns, were studied. MAIN OUTCOME MEASURES--Fatal and nonfatal ischaemic heart disease events. RESULTS--Risk of major ischaemic heart disease events was significantly increased at haematocrit levels of , or = 46.0%. Men with raised haematocrit (, or = 46.0%) showed a 30% increase in relative risk (RR) of major ischaemic heart disease events (RR = 1.32; 95% confidence intervals (CI) 1.10,1.57, p , 0.01) compared with those with values below 46.0%, even after adjustment for age, social class, smoking, body mass index, physical activity, blood cholesterol, lung function (FEV1), and ...
Fertility and pregnancy issues are of key importance for young breast cancer patients. Despite several advances in the field, there are still multiple unmet needs and barriers in discussing and dealing with these concerns. To address the significant challenges related to fertility and pregnancy issues, the PREgnancy and FERtility (PREFER) study was developed as a national comprehensive program aiming to optimize care and improve knowledge around these topics. The PREFER study is a prospective cohort study conducted across several Italian institution affiliated with the Gruppo Italiano Mammella (GIM) group evaluating patterns of care and clinical outcomes of young breast cancer patients dealing with fertility and pregnancy issues. It is composed of two distinctive studies: PREFER-FERTILITY and PREFER-PREGNANCY. The PREFER-FERTILITY study is enrolling premenopausal patients aged 18-45 years, diagnosed with non-metastatic breast cancer, who are candidates to (neo)adjuvant chemotherapy and not previously
Grieving relatives can suffer from numerous consequences like anxiety, depression, post-traumatic stress disorder (PTSD) symptoms, and prolonged grief. This study aims to assess the psychological consequences of grieving relatives after patients death in French palliative care units and their needs for support. This is a prospective observational multicenter mixed study. Relatives of adult patients with a neoplasia expected to be hospitalized more than 72 h in a palliative care unit for end-of-life issues will be included within 48 h after patient admission. End-of-life issues are defined by the physician at patient admission. Relatives who are not able to have a phone call at 6-months are excluded. The primary outcome is the incidence of prolonged grief reaction defined by an ICG (Inventory Complicate Grief) | 25 (0 best-76 worst) at 6 months after patient death. Prespecified secondary outcomes are the risk factors of prolonged grief, anxiety and depression symptoms between day 3 and day 5 and at 6
Objective: To report adverse events (AEs) seen in a large cohort of patients with Juvenile Idiopathic Arthritis (JIA) treated with TNFα blockers (Infliximab and Etanercept).. Methods: All JIA patients treated with Infliximab or Etanercepet at the Paediatric Rheumatologic Centre of the G. Pini Institute (Milan) from November 1999 to February 2006, were enrolled in an open, monocenter, long-term prospective study.. Results: 163 patients (68 Infliximab, 95 Etanercept) were enrolled. Mean onset age 6.4±4.8 years, mean age 17.19.2 years, mean therapy duration 22.9±17.6 months. 45 patients (32 Infliximab, 13 Etanercept) failed to respond to or did not tolerate the first biologic and switched to a second one. 208 treatments (81 Infliximab, 127 Etanercept) were done. 71 AEs occurred in 51 (62.9%) Infliximab patients and led to discontinuation in 26 (32.1%). 133 AEs occurred in 69 (54.3%) Etanercept patients and led to discontinuation in 18 (14.2%). Some AEs, such as thrombocytopenia, ...
TY - JOUR. T1 - A dose-response meta-analysis of the impact of body mass index on stroke and all-cause mortality in stroke patients. T2 - a paradox within a paradox. AU - Bagheri, M.. AU - Speakman, J. R.. AU - Shabbidar, S.. AU - Kazemi, F.. AU - Djafarian, K.. N1 - Acknowledgements We thank Dr. Nicola Orsini for helping us with the statistical analysis. This study was supported by Tehran University of Medical Sciences.. PY - 2015/5. Y1 - 2015/5. N2 - The obesity paradox is often attributed to fat acting as a buffer to protect individuals in fragile metabolic states. If this was the case, one would predict that the reverse epidemiology would be apparent across all causes of mortality including that of the particular disease state. We performed a dose-response meta-analysis to assess the impact of body mass index (BMI) on all-cause and stroke-specific mortality among stroke patients. Data from relevant studies were identified by systematically searching PubMed, OVID and Scopus databases and were ...
TY - JOUR. T1 - Re. T2 - the natural history of penile length after radical prostatectomy: a long-term prospective study.. AU - Morey, Allen F.. PY - 2013/8. Y1 - 2013/8. UR - http://www.scopus.com/inward/record.url?scp=84887337808&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84887337808&partnerID=8YFLogxK. M3 - Article. C2 - 23845350. AN - SCOPUS:84887337808. VL - 190. SP - 592. JO - Journal of Urology. JF - Journal of Urology. SN - 0022-5347. IS - 2. ER - ...
Jehan, I., Harris, H., Salat, S., Zeb, A., Mobeen, N., Pasha, O., ... Goldenberg, R. L. (2009). Neonatal mortality, risk factors and causes: A prospective population-based cohort study in urban Pakistan. Bulletin of the World Health Organization, 87(2), 130-138. DOI: 10.2471/BLT.08.050963 ...
OBJECTIVES: If proven acceptable, safe and effective, the diaphragm could be used as a female-controlled method of preventing both sexually-transmitted infections (STIs) and pregnancy. This studys aim was to assess the acceptability and safety of the diaphragm among sexually-active women in Mombasa, Kenya. METHODS: We conducted a 6-month prospective study among female sex workers (FSWs), and women attending sexual and reproductive health services. Diaphragm acceptability was assessed using continuation rates and factors associated with acceptability. Safety evaluations included colposcopy findings and incidence of urinary tract infections (UTIs) and STIs. RESULTS: Half the 185 participants were FSWs who had less schooling and were less likely to be married than other women. After 6 months, 55% (56/102) of sexually-active women reported having used the diaphragm each sex act during the preceding month. Women liked using the diaphragm (95%, 104/109), and 96% (125/130) reported willingness to ...
BÜHLMANN fCAL® ELISA Citation: Beswick, L. et al. Exploration of predictive biomarkers of early infliximab response in acute severe colitis: A prospective pilot study. Journal of Crohns and Colitis. 2017 Nov 7. DOI: 10.1093/ecco-jcc/jjx146. PMID: 29121178 . Highlight from this Publication
Atrial fibrillation (AF) after thoracic surgery is a continuing source of morbidity and mortality. The effect of postoperative AF on long-term survival however has not been studied. Our aim was to evaluate the impact of AF on early outcome and on survival | 5 years after pulmonary lobectomy for lung cancer. From 1996 to June 2009, 454 consecutive patients undergoing lobectomy for lung cancer were enrolled and followed-up until death or study end (October 2010). Patients with postoperative AF were identified; AF was investigated with reference to its predictors and to short- and long-term survival (| 5 years). Hospital mortality accounted for 7 patients (1.5%), while postoperative AF occurred in 45 (9.9%). Independent AF predictors were: preoperative paroxysmal AF (odds ratio [OR] 5.91; 95%CI 2.07 to 16.88), postoperative blood transfusion (OR 3.61; 95%CI 1.67 to 7.82) and postoperative fibro-bronchoscopy (OR 3.39; 95%CI 1.48 to 7.79). Patients with AF experienced higher hospital mortality (6.7% vs. 1.0%
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IMPORTANCE: Muscle pain, fatigue, and weakness are common adverse effects of statin medications and may decrease physical activity in older men. OBJECTIVE: Determine whether statin use is associated with physical activity, longitudinally and cross-sectionally. DESIGN, SETTING, AND PARTICIPANTS: Men participating in the Osteoporotic Fractures in Men Study, a multicenter prospective cohort study of community-living men age 65+, enrolled between March 2000-April 2002. EXPOSURE: Statin use as determined by an inventory of medications (taken within last 30 days). In cross-sectional analyses, statin use categories were: users and nonusers. In longitudinal analyses, categories were: prevalent users (baseline use and throughout study), new users (initiated use during the study) and nonusers (never used). MAIN OUTCOMES AND MEASURE: Self-reported physical activity at baseline and 2 follow-up visits using the Physical Activity Scale for the Elderly (PASE). At the third visit, an accelerometer measured ...
TY - JOUR. T1 - Association between dietary whole grain intake and risk of mortality. T2 - Two large prospective studies in US Men and Women. AU - Wu, Hongyu. AU - Flint, Alan J.. AU - Qi, Qibin. AU - Van Dam, Rob M.. AU - Sampson, Laura A.. AU - Rimm, Eric B.. AU - Holmes, Michelle D.. AU - Willett, Walter C.. AU - Hu, Frank B.. AU - Sun, Qi. PY - 2015/3/1. Y1 - 2015/3/1. N2 - IMPORTANCE: Higher intake of whole grains has been associated with a lower risk of major chronic diseases, such as type 2 diabetes mellitus and cardiovascular disease (CVD), although limited prospective evidence exists regarding whole grains association with mortality. OBJECTIVE: To examine the association between dietary whole grain consumption and risk of mortality. DESIGN, SETTING, AND PARTICIPANTS: We investigated74 341 women from the Nurses Health Study (1984-2010) and 43 744 men from the Health Professionals Follow-Up Study (1986-2010), 2 large prospective cohort studies. All patients were free of CVD and cancer ...
OBJECTIVE To investigate the association of vitamin D status with all-cause mortality in a Norwegian population and the potential influences of existing chronic diseases on the association. DESIGN A population-based prospective cohort study. SETTING Nord-Trøndelag County, Norway. PARTICIPANTS A random sample (n=6613) of adults aged 20 years or older in a cohort. METHODS Serum 25-hydroxyvitamin D (25(OH)D) levels were measured in blood samples collected at baseline (n=6377). Mortality was ascertained from the Norwegian National Registry. Cox regression models were applied to estimate the HRs with 95% CIs for all-cause mortality in association with serum 25(OH)D levels after adjustment for a wide spectrum of confounding factors as well as chronic diseases at baseline. RESULTS The median follow-up time was 18.5 years, during which 1539 subjects died. The HRs for all-cause mortality associated with the first quartile level of 25(OH)D (|34.5 nmol/L) as compared with the fourth quartile (≥58.1
Drug utilization evaluation (DUE) is an effective program to identify variability in drug use and to support interventions that will improve patient outcomes. The appropriate use of enoxaparin, a low molecular weight heparin (LMWH), which is widely used as curative or preventive treatment of thromboembolic disorders was assessed in the study. A prospective DUE was carried out at Masih Daneshvari teaching hospital. Criteria for the appropriate use of enoxaparin was used to evaluate prescription and administration patterns in this hospital. Enoxaparin utilization of 147 inpatients was reviewed. A total of 944 variables (70.92%) in the regimen, among all subjects, were rated as appropriate and 382 (28.70%) were rated as inappropriate for the conditions diagnosed. The results of this study showed that inappropriate dosing, administration and prescribing of enoxaparin is rather common in masih hospital. Educational programs and implementation of protocols may be needed in the teaching hospitals to control
© 2016 The Authors Introduction Wide local excision and adjuvant radiotherapy is the standard of care for early breast cancer. For large tumours, however, mastectomy is frequently recommended as conventional breast-conserving techniques often result in poor cosmetic outcomes. Therapeutic mammaplasty (TM) may extend the boundaries of breast-conserving surgery by combining breast reduction and mastopexy techniques with tumour excision, preserving a natural breast shape and avoiding the need for mastectomy. The prevalence of this operative option among surgeons in the UK and its success rate are unknown. The TeaM study is a multicentre prospective study that aims to investigate the practice and outcomes of TM. Methods and analysis Breast centres performing TM will be invited to participate through the research collaborative network and the professional associations. All patients undergoing TM between September 2016 and March 2017 will be included. Demographic, operative, oncological and complication data
BACKGROUND: Chronic, low-grade inflammation is an established risk factor for cardiovascular disease. The inflammatory impact of diet can be reflected by concentrations of inflammatory markers in the bloodstream and the inflammatory potential of diet can be estimated by the dietary inflammatory index (DII(TM)), which has been associated with cardiovascular disease risk in some previous studies. We aimed to examine the association between the DII and the risk of first myocardial infarction (MI) in a population-based study with long follow-up.. METHOD: We conducted a prospective case-control study of 1389 verified cases of first MI and 5555 matched controls nested within the population-based cohorts of the Northern Sweden Health and Disease Study (NSHDS), of which the largest is the ongoing Västerbotten Intervention Programme (VIP) with nearly 100 000 participants during the study period. Median follow-up from recruitment to MI diagnosis was 6.4 years (6.2 for men and 7.2 for women). DII scores ...
RESULTS: By age 4 years, the cumulative incidence of stuttering onset was 11.2% (95% confidence interval [CI]: 9.7% to 12.8%). Higher maternal education (P = .004), male gender (P = .02), and twinning (P = .005) predicted stuttering onset. At outcome, stuttering children had stronger language (mean [SD]: 105.0 [13.0] vs 99.6 [14.6]; mean difference 5.5, 95% CI: 3.1 to 7.8; P , .001) and nonverbal cognition (mean [SD]: 106.5 [11.4] vs 103.9 [13.7], mean difference 2.6, 95% CI: 0.4 to 4.8; P = .02) and better health-related quality of life but were otherwise similar to their nonstuttering peers. Only 9 of 142 children (6.3%; 95% CI: 2.9% to 11.7%) recovered within 12 months of onset. ...
Rheumatoid arthritis (RA) is a progressive disease, often leading to disability. Because the disease course develops rapidly during the first years after diagnosis, more knowledge is needed about the early disease course to minimize later disability. This thesis describes the course of disability in early RA such as hand function, pain intensity, activity limitation and sick leave. In addition, this thesis compares disability between women and men and compares disability between RA patients and referents.. This thesis is primarily based on data from the 320 patients that were included in the multi-centre project in Sweden called Early interventions in rheumatoid arthritis (TIRA). A wide range of outcome variables was registered between 1996 and 2006 during regular follow-ups from time for diagnosis through the eight-year follow-up. Outcome regarding disease activity and disability of RA patients still remaining in TIRA at the three and five year follow-up respectively are used in this thesis. ...
As part of a project to examine health care ethics consultation in Canada, we surveyed individuals who were considered by themselves or others to play a significant role in health care ethics consultation. Since one goal ...
Risikoforebygging er en viktig del av alt helsearbeid, men det meste av evidens med hensyn på forebyggende helsearbeid er fremkommet ved studier utført på middelaldrende befolkningsgrupper med ulik ekstern validitet, med variabel oppfølgingstid, og med overvekt av menn. Modifiserbare risikofaktorer har potensielt ulik innvirkning i ulike aldersgrupper, i ulike faser av en lengre oppfølgingstid og med hensyn på forskjellige endepunkter (dødelighet: total og årsaksspesifikk). Målsetning: å studere forskjeller og likheter i effekten av livsstilsrelaterte risikofaktorer (særlig kroppsmasseindeks, fysisk aktivitet og lungefunksjon) på total dødelighet og årsaksspesifikk dødelighet som følge av hjerneslag og koronar hjertesykdom i ulike aldersgrupper av menn og kvinner i en generell norsk befolkning med 42 års oppfølgingstid. Materiale og metode: 6811 tilfeldig utvalgte menn og kvinner i alderen 20-79 og bosatt i Bergen i 1964 ble invitert til en utvidet helseundersøkelse etter ...
Purpose: : To study the natural history and the major risk factors of ROP among the infants in Taiwan. Methods: : A prospective natural history study of ROP was performed for all premature infants from June 2010 to July 2011 at our childrens hospital. Patients were screened with birth weight (BW) less than 1500 grams or gestational age (GA) less than 32 weeks or selected infants with BW more than 1500 grams or GA more than 32 weeks with an unstable clinical course, including those requiring cardiorespiratory support and who are believed to be high risk by their pediatrician. The incidence of advanced ROP, the need for laser, Bevacizumab, or vitrectomy treatment was documented. The associated risk factors for the development of ROP were recorded. Results: : We enrolled 223 premature infants, and 98 infants (44%) developed ROP. The mean gestational age (GA) was 29.2 ± 3.0 (range 28-36) weeks and the mean BW was 1247.0 ± 441.5 (range 700-2705) grams. The incidence of ROP among BW more and less ...
Background: Physical activity (PA) is considered a cornerstone of diabetes mellitus management to prevent complications, but conclusive evidence is lacking. Methods: This prospective cohort study and meta-analysis of existing studies investigated the association between PA and mortality in individuals with diabetes. In the EPIC study (European Prospective Investigation Into Cancer and Nutrition), a cohort was defined of 5859 individuals with diabetes at baseline. Associations of leisure-time and total PA and walking with cardiovascular disease (CVD) and total mortality were studied using multivariable Cox proportional hazards regression models. Fixed-and random-effects meta-analyses of prospective studies published up to December 2010 were pooled with inverse variance weighting. Results: In the prospective analysis, total PA was associated with lower risk of CVD and total mortality. Compared with physically inactive persons, the lowest mortality risk was observed in moderately active persons: ...
Evidence indicates that gaining weight in adult life is associated with an elevated risk of colorectal cancer; however, biological mechanisms that may explain this association remain unclear. We evaluated the mediation effect of 20 different biomarkers on the relationship between adult weight gain and colorectal cancer, using data from a prospective nested case-control study of 452 incident cases diagnosed between 1992 and 2003 and matched within risk sets to 452 controls within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The proportions of mediated effects (%) were estimated on the basis of differences in percent effect changes in conditional logistic regression models with and without additional adjustment for individual biomarkers. Greater adult weight gain (≥300 g/year vs. ,300 g/year) was associated with a higher risk of colon cancer (multivariable-adjusted relative risk = 1.54, 95% confidence interval: 1.07, 2.24) but not rectal cancer (relative risk = ...
Evidence indicates that gaining weight in adult life is associated with an elevated risk of colorectal cancer; however, biological mechanisms that may explain this association remain unclear. We evaluated the mediation effect of 20 different biomarkers on the relationship between adult weight gain and colorectal cancer, using data from a prospective nested case-control study of 452 incident cases diagnosed between 1992 and 2003 and matched within risk sets to 452 controls within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The proportions of mediated effects (%) were estimated on the basis of differences in percent effect changes in conditional logistic regression models with and without additional adjustment for individual biomarkers. Greater adult weight gain (≥300 g/year vs. ,300 g/year) was associated with a higher risk of colon cancer (multivariable-adjusted relative risk = 1.54, 95% confidence interval: 1.07, 2.24) but not rectal cancer (relative risk = ...
Abstract Background Few prospective studies on association between waist circumference and hypertension have | Wenshu Luo, Zhirong Guo, Xiaoshu Hu, Zhengyuan Zho | International Journal of Cardiology |
Objective: It has been suggested that lipid-lowering treatment with the use of statins adversely affects the steroid hormones. However, the safety of lipid lowering treatment targeting very low levels of LDL with respect to the steroid hormones has not been established. Research design and methods: A prospective, randomized, multicenter trial was conducted involving 98 patients. The patients were randomized into 2 groups: group-I received 10 mg of atorvastatin plus 10 mg of ezetimibe and group-II 80 mg of atorvastatin for the first 3 months. After crossover, the first group received 80 mg of atorvastatin and the second group 10 mg of atorvastatin plus 10 mg of ezetimibe for the following 3 months. Cortisol, DHEAS, testosterone, and estradiol levels were measured at the enrollment and at the end of the 1(st), 2(nd), 3(rd), and 6(th) months. Results: Along with a decrease in LDL level, the levels of DHEAS, testosterone, and estradiol decreased in both groups ( ...
Poster: EuroSafe Imaging 2019 / ESI-0043 / Influence of BMI on clinical DRLs for CT examinations: a prospective multicenter study after protocol harmonization and optimization. by: H. Brat1, F. Zanca2, B. Rizk3, S. Montandon4, D. Racine5, D. Fournier1; 1Institut de Radiologie de Sion Sion/CH, 2Palindromo Heverlee/BE, 3Centre dImagerie de Fribourg Fribourg/CH, 4Philips Medical Systems Bussigny/CH, 5Institut de Radiophysique Appliquee Lausanne/CH
In this large prospective study among US men and women who were on average age 73 years at baseline, greater walking, leisure-time activity, and exercise intensity were inversely associated with CHD, stroke (especially ischemic stroke), and total CVD. To our knowledge, this is the first large prospective community-based study including a large number of participants ,70 years and having updated PA over time, to demonstrate independent associations of PA measures with lower incidence of CHD, stroke, and total CVD. Results were robust in a range of sensitivity analyses. When different types of PA were simultaneously evaluated, greater walking and, to a lesser extent, exercise intensity were independently associated with lower risk, whereas leisure-time activity was not independently associated with risk.. With aging, the risk of developing and dying of chronic diseases such as CVD increases dramatically.26 In many countries in the world, the proportion of the population ,60 years is increasing ...
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A total of 36 studies were included, with 1,279,804 subjects and 36,352 CVD cases. Duration of follow-up for incident CVD ranged from 6-44 years, with a median follow-up of 10 years. Twenty-one studies were conducted in Europe, 12 in the United States, and three in Japan. A nonlinear relationship of coffee consumption with CVD risk was identified (p for heterogeneity = 0.09, p for trend < 0.001, p for nonlinearity < 0.001). Compared with the lowest category of coffee consumption (median, 0 cups per day), the relative risk of CVD was 0.95 (95% confidence interval [CI], 0.87-1.03) for the highest category (median, 5 cups per day), 0.85 (95% CI, 0.80-0.90) for the second highest category (median, 3.5 cups per day), and 0.89 (95% CI, 0.84-0.94) for the third highest category (median, 1.5 cups per day). Coffee consumption was nonlinearly associated with both coronary heart disease and stroke risks.. ...
article{8645532, author = {Seibold, Petra and Webb, Adam and Aguado-Barrera, Miguel E. and Azria, David and Bourgier, Celine and Brengues, Muriel and Briers, Erik and Bultijnck, Renée and Calvo-Crespo, Patricia and Carballo, Ana and Choudhury, Ananya and Cicchetti, Alessandro and Claßen, Johannes and Delmastro, Elena and Dunning, Alison M. and Elliott, Rebecca M. and Fachal, Laura and Farcy-Jacquet, Marie-Pierre and Gabriele, Pietro and Garibaldi, Elisabetta and Gómez-Caamaño, Antonio and Gutiérrez-Enríquez, Sara and Higginson, Daniel S. and Johnson, Kerstie and Lobato-Busto, Ramón and Mollà, Meritxell and Müller, Anusha and Payne, Debbie and Peleteiro, Paula and Post, Giselle and Rancati, Tiziana and Rattay, Tim and Reyes, Victoria and Rosenstein, Barry S. and De Ruysscher, Dirk and De Santis, Maria Carmen and Schäfer, Jörg and Schnabel, Thomas and Sperk, Elena and Symonds, R. Paul and Stobart, Hilary and Taboada-Valladares, Begoña and Talbot, Christopher J. and Valdagni, Riccardo ...
Summary of the first prospective study - published online February 13, 2012 in the Journal of Clinical Oncology - to provide strong evidence of increased breast and pancreatic cancer risk in individuals with Lynch syndrome, who carry certain inherited genetic mutations in DNA repair genes. The study is also the first to show that relatives of people with Lynch syndrome who do not carry these mutations have no increased risk of cancer
BACKGROUND: Caffeine intake has been inversely associated with Parkinsons disease (PD) risk. This relationship may be modified by polymorphisms of glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A) and cytochrome P450 1A2 (CYP1A2), but the results of previous studies have been inconsistent. METHOD: We examined the interaction of caffeine intake with GRIN2A-rs4998386 and CYP1A2-rs762551 polymorphisms in influencing PD risk among 829 incident cases of PD and 2,754 matched controls selected among participants in the following 3 large prospective ongoing cohorts: the Nurses Health Study, the Health Professionals Follow-up Study, and the Cancer Prevention Study II Nutrition Cohort ...
International Journal of Pharmacy and Pharmaceutical Research (IJPPR) will give best paper award every year in the form of money along with certificate to support research activity of scholar ...
IMPRESS 2 Study: International Multicentric prospective study on PREgnancy in Systemic Sclerosis Patients with systemic sclerosis who plan a pregnancy for the years 2013-16 may be interested in participating in an international observational prospective study initiated by EUSTAR on pregnancy in wome...
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International Scholarly Research Notices is a peer-reviewed, Open Access journal covering a wide range of subjects in science, technology, and medicine. The journals Editorial Board as well as its Table of Contents are divided into 108 subject areas that are covered within the journals scope.
Mainly Im working on cancer epidemiology, especially in nutritional factors, in genetic factors that contribute to carcinogenesis. I work with a large European cohort called EPIC, the European Prospective Investigation of Cancer and Nutrition, which has sampled half a million Europeans at baseline, so when everyone was healthy. Then we follow these people up over the intervening years to find out what kind of cancers they develop. That gives us the chance to closely match them with other people in the cohort who didnt develop these cancers and so, very important, we can have this very close case-controlled matching. Because the samples were taken before diagnosis this helps to minimise issues to do with reverse causality, the fact that things go awry when you have a disease, so its very difficult to say whether these factors are implicated in the disease or theyre just because you have a disease. So this is the power of this kind of study design, prospective cohort.. What are the results so ...
A study suggests that smoking and heavy drinking can make a person look older than his/her actual age. Heavy drinking and smoking are linked to visible signs of physical ageing and the consequences reflect on a persons face, sooner or later. Light to moderate drinking is not associated with looking older than ones years, the findings showed. "This is the first prospective study to show that alcohol and smoking are associated with the development of visible age-related signs and thus generally looking older than ones actual age," said the researchers. The findings are based on information from more than 11,500 adults in Denmark whose heart health and visible ageing signs were tracked for an average of 11.5 years as part of the Copenhagen City Heart Study. Before each of the clinic visits, researchers quizzed the participants about their lifestyle and general health and asked to state how much they drank and smoked. And they were checked for four signs of ageing that have previously been linked ...
TY - JOUR. T1 - A prospective comparison of alginate-hydrogel with standard medical therapy to determine impact on functional capacity and clinical outcomes in patients with advanced heart failure (AUGMENT-HF trial). AU - Anker, Stefan D.. AU - Coats, Andrew J.S.. AU - Cristian, Gabriel. AU - Dragomir, Dinu. AU - Pusineri, Enrico. AU - Piredda, Massimo. AU - Bettari, Luca. AU - Dowling, Robert. AU - Volterrani, Maurizio. AU - Kirwan, Bridget Anne. AU - Filippatos, Gerasimos. AU - Mas, Jean Louis. AU - Danchin, Nicolas. AU - Solomon, Scott D.. AU - Lee, Randall J.. AU - Ahmann, Frank. AU - Hinson, Andy. AU - Sabbah, Hani N.. AU - Mann, Douglas L.. PY - 2015/9/7. Y1 - 2015/9/7. N2 - Aims AUGMENT-HF was an international, multi-centre, prospective, randomized, controlled trial to evaluate the benefits and safety of a novel method of left ventricular (LV) modification with alginate-hydrogel. Methods Alginate-hydrogel is an inert permanent implant that is directly injected into LV heart muscle and ...
Original Article Pak Armed Forces Med J 2015; 65(Suppl): S ANALYSIS OF KEY PERFORMANCE INDICATORS AND QUALITY OBJECTIVES OF A TERTIARY CARDIAC CENTER Muhammad Bilal Maqsood, Sabeen Khurshid Zaidi,
Infections of the central nervous system (CNS) are severe conditions, leading to neurological sequelae or death. Knowledge of the causative agents is essential to develop guidelines for case management in resource-limited settings. Between August 2009 and October 2012, we conducted a prospective descriptive study of the aetiology of suspected CNS infections in children two months to 12 years old, with fever and at least one sign of CNS involvement in Mbarara Hospital, Uganda. Children were clinically evaluated on admission and discharge, and followed-up for 6 months for neurological sequelae. Pathogens were identified from cerebrospinal fluid (CSF) and blood using microbiological and molecular methods. We enrolled 459 children. Plasmodium falciparum (36.2%) and bacteria in CSF (13.3%) or blood (3.3%) were the most detected pathogens. Viruses were found in 27 (5.9%) children. No pathogen was isolated in 207 (45.1%) children. Patterns varied by age and HIV status. Eighty-three (18.1%) children ...
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PRF readers can get free access to a selected Journal of Pain paper each month, thanks to the American Pain Society. Get the free full text of the selection from the December 2017 issue here.. ...
TY - JOUR. T1 - Size at birth and height in early adolescence. T2 - A prospective birth cohort study. AU - Araújo, Cora L P. AU - Hallal, Pedro C.. AU - Nader, Gisele A.. AU - Menezes, Ana Maria B. AU - Victora, Cesar G.. PY - 2008/4. Y1 - 2008/4. N2 - The aim of this study was to evaluate the association between size at birth (birthweight and birth length) and height in early adolescence in a prospective birth cohort study in Pelotas, Rio Grande do Sul, Brazil. Interviews were carried out in 1993, including measurements of birthweight and length, and in 2004-2005, including measurements of weight and height. This analysis includes 4,452 individuals, with a mean age of 11.3 years (standard deviation - SD = 0.3), representing a follow-up rate of 87.5%. Mean height at 11 years was 145.8 cm (SD = 7.9), or 144.9 cm (SD = 7.7) in boys and 146.8 cm (SD = 7.9) in girls. Birthweight and birth length were positively associated with height in early adolescence in the crude analysis, but after adjustment ...
Background: Febrile seizures are one of the most common neurological conditions of childhood. It seems that zinc deficiency is associated with increased risk of febrile seizures.Aim: To estimate the serum Zinc level in children with simple Febrile seizures and to find the correlation between serum zinc level and simple Febrile seizures.Materials and Methods: The proposed study was a hospital based prospective case control study which included infants and children aged between 6 months to 5 years, at Post Graduate Department of Pediatrics, (SMGS) Hospital, GMC Jammu, northern India. A total of 200 infants and children fulfilling the inclusion criteria were included. Patients were divided into 100(cases) in Group A with simple febrile seizure and 100(controls) in Group B of children with acute febrile illness without seizure. All patients were subjected to detailed history and thorough clinical examination followed by relevant investigations.Results: Our study had slight male prepondance of 62% in cases
In our study, we found that the intake of isoflavones, miso soup, and soy food was not clearly associated with overall colorectal cancer in either men or women. However, the risk of proximal colon cancer in men decreased with increasing consumption of isoflavones, miso soup, and soy food. In contrast, we found no association for distal colon or rectal cancer in men or women. To our knowledge, this is the first cohort study to investigate the association between a large variety of dietary soy foods and isoflavone intake and the risk of colorectal cancer, including anatomic subsites in a general population. These findings suggest that the intake of isoflavones, miso soup, and soy food may not be associated with the risk of colorectal cancer in Japanese men and women.. These epidemiologic findings for dietary soy and isoflavone intake and colorectal cancer risk are partially consistent with the results of a previous cohort study (14) in women, four case-control studies in men and women combined (9, ...
Data on non-specific effects of BCG vaccination in well described, general population African cohorts is scanty. We report the effects of BCG vaccination on post-neonatal infant and post-infancy mortality in a cohort of children in Mbale, Eastern Uganda. A community-based prospective cohort study was conducted between January 2006 and February 2014. A total of 819 eligible pregnant women were followed up for pregnancy outcomes and survival of their children up to 5 years of age. Data on the childrens BCG vaccination status was collected from child health cards at multiple visits between 3 weeks and 7 years of age. Data was also collected on mothers residence, age, parity, household income, self-reported HIV status as well as place of birth. Multivariable Cox proportional hazards regression models taking into account potential confounders were used to estimate the association between BCG vaccination and child survival. The neonatal mortality risk was 22 (95% CI: 13, 35), post-neonatal infant mortality
en] Background Drug-resistant chronic duster headache (drCCH) is a devastating disorder for which various destructive procedures have been tried unsuccessfully. Occipital nerve stimulation (ONS) is a new, safe strategy for intractable headaches. We undertook a prospective pilot trial of ONS in drCCH to assess clinical efficacy and pain perception. Methods Eight patients with drCCH had a suboccipital neurostimulator implanted on the side of the headache and were asked to record details of frequency, intensity, and symptomatic treatment for their attacks in a diary before and after Continuous ONS. To detect changes in cephalic and extracephalic pain processing we measured electrical and pressure pain thresholds and the nociceptive blink reflex. Findings Two patients were pain free after a follow-up of 16 and 22 months; one of them still had occasional autonomic attacks. Three patients had around a 90% reduction in attack frequency. Two patients, one of whom had had the implant for only 3 months, ...
Studies on leisure time physical activity as risk factor or protective factor for knee or hip osteoarthritis (OA) show divergent results. Longitudinal prospective studies are needed to clarify the association of physical activity with future OA. The aim was to explore in a prospective population-based cohort study the influence of leisure time physical activity on severe knee or hip OA, defined as knee or hip replacement due to OA. Leisure time physical activity was reported by 28320 participants (mean age 58 years (SD 7.6), 60% women) at baseline. An overall leisure time physical activity score, taking both duration and intensity of physical activities into account, was created. The most commonly reported activities were also used for analysis. The incidence of knee or hip replacement due to OA over 11 years was monitored by linkage with the Swedish hospital discharge register. Coxs proportional hazards model (crude and adjusted for potential confounding factors) was used to assess the incidence of
The Kuopio ischaemic heart disease risk factor study is a population study designed to investigate risk factors for cardiovascular diseases, atherosclerosis, and related outcomes in men from eastern Finland.18 The baseline examinations were carried out between March 1984 and December 1989. The study sample included 3235 eligible men aged 42, 48, 54, or 60 at the baseline examination; 2682 (82.9%) participated. Men with symptomatic coronary heart disease (n = 92) or ischaemia on maximal exercise testing (n = 359),19 or both (n = 585), were excluded from the current analyses. Of the remaining 1646 men, 1605 had data on plasma ascorbate concentration at baseline.. The examination protocol and measurements have been described.10 11 12 13 Plasma ascorbate concentrations were determined by a chromatographic method in deep frozen samples, which were stabilised in 5% metaphosphoric acid immediately after sampling.20 The coefficient of variation between 12 batches was 7.2%.20. Plasma ascorbate ...
Background: Sugar-sweetened carbonated beverages (called soft drinks) and juices, which have a high glycemic load relative to other foods and beverages, have been hypothesized as pancreatic cancer risk factors. However, data thus far are scarce, especially from non-European descent populations. We investigated whether higher consumption of soft drinks and juice increases the risk of pancreatic cancer in Chinese men and women.. Methods: A prospective cohort analysis was done to examine the association between soft drink and juice consumption and the risk of pancreatic cancer in 60,524 participants of the Singapore Chinese Health Study with up to 14 years of follow-up. Information on consumption of soft drinks, juice, and other dietary items, as well as lifestyle and environmental exposures, was collected through in-person interviews at recruitment. Pancreatic cancer cases and deaths were ascertained by record linkage of the cohort database with records of population-based Singapore Cancer ...
Field Use and Prospective Studies[edit]. Despite the medical advances of detection, diagnosis and treatment methods throughout ... According to the American Journal of Respiratory and Critical Care Medicine, a prospectivestudy was conducted to determine the ... A Prospective Study". American Journal of Respiratory and Critical Care Medicine. 174: 982-989. doi:10.1164/rccm.200603-344oc. ... The overall diagnostic yield found in the present study is superior to rates reported in most previous studies performed for ...
Meta-analysis of prospective studies". Circulation. 102 (10): 1082-85. doi:10.1161/01.CIR.102.10.1082. PMID 10973834. Archived ... systematic review and dose-response meta-analysis of prospective cohort studies". BMJ (Clinical Research Ed.). 349: g4490. doi: ... meta-analysis of 141 cohort studies in 55 study reports". BMJ. 360: j5855. doi:10.1136/bmj.j5855. PMC 5781309 . PMID 29367388. ... The Stockholm Female Coronary Angiography Study". J. Intern. Med. 261 (3): 245-54. doi:10.1111/j.1365-2796.2006.01759.x. PMID ...
Systematic review of prospective cohort studies". BMJ (Clinical research ed.). 318 (7196): 1460-67. doi:10.1136/bmj.318.7196. ... Based on comparative studies, Marmot argues that we can make our society more participatory and inclusive to increase overall ... "Intersalt: An international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium ... He leads the English Longitudinal Study of Ageing (ELSA), and is engaged in several international research efforts on the ...
A prospective study". J Reprod Med. 27 (6): 321-7. PMID 7120209.. ... "Studies in Family Planning. 45 (3): 301-14. doi:10.1111/j.1728-4465.2014.00393.x. PMC 4727534 . PMID 25207494.. ... Shehan, Constance L. (2016). The Wiley Blackwell Encyclopedia of Family Studies, 4 Volume Set. John Wiley & Sons. p. 406. ISBN ... A study of singleton live births came to the result that childbirth has a standard deviation of 14 days when gestational age is ...
A prospective study". The American Journal of Sports Medicine. 31 (4): 585-89. doi:10.1177/03635465030310041801. PMID 12860549. ...
A prospective study". Am J Sports Med. 31 (4): 585-589. PMID 12860549.. ... Imaging studies, such as ultrasound or MRI, may reveal anatomic abnormalities or masses responsible for the impingement. ...
Prospective studies collaboration». Lancet, 346, 8991-8992, 1995, pàg. 1647-53. DOI: 10.1016/S0140-6736(95)92836-7. PMID: ... UK Prospective Diabetes Study (UKPDS) Group». Lancet, 352, 9131, 1998, pàg. 837-53. DOI: 10.1016/S0140-6736(98)07019-6. PMID: ... Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone ... The Framingham Study». Arch. Intern. Med., 147, 9, 1987, pàg. 1561-4. DOI: 10.1001/archinte.147.9.1561. PMID: 3632164. ...
Retrospective and prospective studies. Acta Paediatrica Scandinavica Suppl. 1979, 275: 112-21. PMID 291283.. ... Goddard, H.H. (1912). The Kallikak Family: A Study in the Heredity of Feeble-Mindedness. New York: Macmillan. ... Committee to Study Fetal Alcohol Syndrome, Division of Biobehavioral Sciences and Mental Disorders, Institute of Medicine. ... Strömland K, Pinazo-Durán M. Ophthalmic involvement in the fetal alcohol syndrome: clinical and animal model studies. Alcohol ...
The last active longitudinal prospective study ended in 2000 with the end of the 36-year Denver study following the death of ... In prospective studies of 47,XYY boys identified by newborn screening programs, the IQ scores of 47,XYY boys were usually ... Prospective studies on children with sex chromosome aneuploidy. Birth defects original article series 22 (3). New York: Alan R ... In a summary of six prospective studies of 47,XYY boys identified by newborn screening programmes, twenty-eight 47,XYY boys had ...
A prospective study". European Journal of Vascular and Endovascular Surgery. 34 (3): 361-6. doi:10.1016/j.ejvs.2007.03.020. ...
A prospective study". J Bone Joint Surg Am. 88 (6): 1251-7. doi:10.2106/JBJS.E.00216. PMID 16757758. Frick SL (April 2006). " ...
A prospective study". Am J Sports Med. 31 (4): 585-589. PMID 12860549. Thomas, Jennifer (2 June 2009). "'Cell Phone Elbow' -- A ... Imaging studies, such as ultrasound or MRI, may reveal anatomic abnormalities or masses responsible for the impingement. ...
Armson CJ, Pollard CW, Child cyclist injuries; a prospective study. Feb 3 Vol 144, Med.J.Aust. 1986. O'Rourke NA, Costello F, ... Studies of helmet use by injured cyclists were published from the late 1980s, some in Australia, both before and after helmet ... McDermott, F. T.; Lane, J. C.; Brazenor, G. A.; Debney, A. E. (1993). "The effectiveness of bicyclist helmets: a study of 1710 ... The results of a comparative study of the injury profiles of Victorian motorcyclist and bicyclist casualties were used by the ...
A prospective study". Rheumatology (Oxford). 40 (2): 147-51. doi:10.1093/rheumatology/40.2.147. PMID 11257150. Jayne DR, Jones ... The same study found that clinical relapse in some patients were in association with the return of circulating B-cells. Based ...
A prospective study]". Forsch Komplementärmed Klass Naturheilkd (in German). 12 (3): 148-51. doi:10.1159/000085212. PMID ... "No credible scientific studies have demonstrated the reliability of LBA for detecting any of the above conditions." Ernst ...
A prospective study". J Bone Joint Surg Br. 69 (5): 840-2. PMID 3680356. Heidelbaugh, JJ; Lee, H (15 February 2009). " ... The study suggested that treatment should not be based on the correction of a non-existent nail deformity. Ingrown toenails are ... In studies of diabetics, who need to avoid surgery when possible, nail bracing was found to be effective at providing immediate ... One study compared patients with ingrown toenails to healthy controls and found no difference in the shape of toenails between ...
A prospective study". J Reprod Med. 27 (6): 321-7. PMID 7120209. Malarewicz A, Szymkiewicz J, Rogala J (September 2006). "[ ... A study of singleton live births came to the result that childbirth has a standard deviation of 14 days when gestational age is ... Studies have shown that light to moderate drinking during pregnancy might not pose a risk to the fetus, although no amount of ... Studies show that skin-to-skin contact between a mother and her newborn immediately after birth is beneficial for both the ...
A Prospective Study". The American Journal of Sports Medicine. 42 (4): 906-911. doi:10.1177/0363546513519964. ISSN 0363-5465. ... There are no studies to date that have reliably documented adverse effects associated with PRP treatment, possibly due to poor ... A 2015 meta-analysis reviewed 551 studies on PRP for osteoarthritic (OA) knee and found that only nine were worth considering ... Among these, the most significant by impact factor is the randomized scientific-clinical study of the clinical-instrumental ...
A prospective study". JAMA. 261 (18): 2663-68. doi:10.1001/jama.1989.03420180087036. PMID 2709546. Rodríguez-Molinero (2015). " ... Rapp (2014). "Fall incidence in Germany: results of two population-based studies, and comparison of retrospective and ... The ProFane taxonomy is currently used as a framework to appraise falls-related research studies in Cochrane Systematic Reviews ... prospective falls data collection methods". BMC Geriatr. 14: 105. doi:10.1186/1471-2318-14-105. PMC 4179843 . PMID 25241278. ...
A prospective study". J Bone Joint Surg Am. 88 (6): 1251-7. doi:10.2106/JBJS.E.00216. PMID 16757758. Kocher MS, Mandiga R, ... A small study showed that the nonsteroidal anti-inflammatory drug ibuprofen could shorten the disease course (from 4.5 to 2 ... Some studies have demonstrated findings on magnetic resonance imaging (MRI scan) that can differentiate between septic ... but further studies did not confirm any link between the two conditions. There are no set standards for the diagnosis of ...
A prospective study of neurologic manifestations of Behçet's disease in 96 Iranian patients". Exp Mol Pathol. 74: 17-22. Al- ... A prospective study". Arch Neurol. 46 (3): 265-269. doi:10.1001/archneur.1989.00520390031011. Yazici H, Fresko I, Yurdakul S ( ... a prospective study from Iraq". J Neurol Neurosurg Psychiatry. 74: 608-13. doi:10.1136/jnnp.74.5.608. Al-Araji, A; Kidd, DP ( ... In one study of 387 Behçet's disease (BD) patients that has been done for 20 years, 13% of men with BD developed to NBD and 5.6 ...
A prospective study". Danish Medical Bulletin. Feinfeld DA, Bargouthi H, Niaz Q, Carvounis CP (2002). "Massive and ...
A prospective study". Arch Surg. 131 (10): 1043-7. doi:10.1001/archsurg.131.10.1043. PMID 8857900. Smeland S, Kolset SO, Lyon M ... Clinical trial number NCT01960348 for "APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment ... a clinicopathological study of a large kindred". Muscle Nerve. 21 (11): 1478-85. doi:10.1002/(SICI)1097-4598(199811)21:11. 3.0. ...
A prospective study". J Reprod Med. 27 (6): 321-. PMID 7120209. Khamis MA; Mustafa MF; Mohamed SN; Toson MM (2007). "Influence ... Some studies in the 1980s and 1990s contend that it is useful for pregnant women to continue to be sexually active, ... In context of this overall decrease in desire, some studies indicate a second-trimester increase, preceding a decrease. However ...
These studies were widely criticized as showing correlation, not causality. Followup prospective cohort studies in the early ... Followup large prospective cohort studies in the early 1950s showed clearly that smokers died faster, and were more likely to ... In a prospective study of community-dwelling people 60-90 years of age, during 1993, of unimmunized people 23% of smokers had ... Case-control studies were published in Germany in 1939 and 1943, and one in the Netherlands in 1948. A case-control study on ...
The prospective P2C2 HIV multicenter study. Circulation 1998;97:1246-56. Lewis W, Grupp IL, Grupp G, et al. Cardiac dysfunction ... The Prospective P2C2 HIV Multicenter Study. Circulation 2000;102:1542-8. Miller TL, Orav EJ, Colan SD, et al. Nutritional ... A lower body mass index is associated with cardiomyopathy in people with HIV infection: evidence from a case comparison study. ... Cardiac involvement in the acquired immunodeficiency syndrome: a multicentre clinical-pathological study. AIDS Res Hum ...
a b c Patti McGill Peterson, The Young Socialist Movement in America from 1905 to 1940: A Study of the Young People's Socialist ... who encouraged prospective SSS teachers to read John Dewey's School and Society to provide a conceptual basis for their work.[ ...
UK Prospective Diabetes Study (UKPDS) Group". Lancet. 352 (9131): 837-53. 1998. PMID [http://www.sciencedirect.com/science?_ob= ... 3. The study you refer to is only one study and is ten years out of date anyway. ... 1. The above study states that "a biologically active form of chromium in mammals, potentiates the effect of insulin". What ... An old study easily to hand may have been since shown to be wrong, in which case it's the obligation of the objector to show ...
Prospective Students. Academic Programs. Applying to Guelph. Meet Our Students. International Applicants. Preview Day. ... Funding Graduate Studies. Forms & Documents. Graduate Fees. Policies & Guidelines. International Students. English Language ...
Research: The International Studies degree places emphasis on research, as a way to both prepare students for graduate study ... What is International Studies?. International Studies is an academic field that crosses traditional disciplinary boundaries, ... The students in International Studies share an interest in language, culture, and travel. They tend to be creative thinkers and ... Because International Studies emphasizes critical thinking, problem-solving skills and cross-cultural competence, the major is ...
Prospective Students. Getting into the Film Major. Film Studies is a much sought-after major, and our limited resources require ... Film studies faculty will evaluate applications based on performance in film studies classes (including but not limited to ... Students who are considering a Film Studies major should consult with the department chair as soon as possible in order to ... To be accepted into the Film Studies major, students are required to have completed two prerequisites, Film 304: History of ...
What is Communication Studies? Our program examines human communication in a variety of context, exploring how communication ... What Communication Studies graduates know at graduation (2-pg. PDF). Facts about CMS. What is communication studies?. The ... Why study communication studies at USM?. Our program enhances skills critical for success in todays society- the ability to ... quantitative and qualitative studies) and a humanistic/rhetorical approach (study of public persuasive messages). ...
... BA Programmes for 2020 entry. Politics. Politics and International Studies. Politics and ... International Studies and Hispanic Studies. Politics, International Studies and Italian. Politics and International Studies ... Politics, International Studies and French. Politics, International Studies and German. Politics, ... As a PAIS student, you will work with experts on a wide variety of topics within politics and international studies. Whether ...
We hope you will consider choosing a course at Trinity for postgraduate study. At Trinity you will embark on an exciting new ... You are here Prospective Students Prospective Students. As a truly international university, we welcome applications from ... Prospective Students who wish to request a copy of the prospectus by post can email the Academic Registry ([email protected] ... We hope you will consider choosing a course at Trinity for postgraduate study. At Trinity you will embark on an exciting new ...
Study Programmes. The Section offers study opportunities at PhD, MPhil or MA level. The PhD and MPhil are full research degrees ... Postgraduate study at both research and taught-course level plays a central role in the Sections approach. Germanic Studies, ... On this programme you can specialise in a single area of study such as Germanic Studies or you can pursue a broader programme ... It houses the internationally unique Centre for Dutch and Flemish Studies and the Centre for Luxembourg Studies and supplies ...
If you would like to visit SUNY Oswego and take a tour of the Communication Studies facilities, please refer to the schedules ...
A prospective cohort study is a longitudinal cohort study that follows over time a group of similar individuals (cohorts) who ... Prospective cohort studies are typically ranked higher in the hierarchy of evidence than retrospective cohort studies and can ... Tsimane Amazonian Panel Study, Bolivia The UK biobank , UK "Definition of prospective cohort study - NCI Dictionary of Cancer ... The prospective study is important for research on the etiology of diseases and disorders. The distinguishing feature of a ...
Retrospective and Prospective Views in DOAJ. DOAJ is an online directory that indexes and provides access to quality open ... Information about the open-access journal Translation Studies: ... Translation Studies: Retrospective and Prospective Views. TSRPV ... Publishers keywords: translation, linguistics, cultural studies. Language of fulltext: German, Italian, Romanian; Moldavian; ...
... which has been developed by researchers within English Studies. ... Undergraduate Study. *Postgraduate Study *Why Study with Us? * ...
Prospective Postgraduate Newsletter January 2018. Funding your future. The deadline for some of our scholarships for MA and PhD ... As one of the top 50 universities in the world for English Studies, we regularly play host to scholars from other institutions ... Durhams Institute of Advanced Study also hosts a number of Fellows every year to explore themes, including those linked to ... Our students also find it possible to take up part-time work alongside their studies, whether on projects within the Department ...
Faculty of Graduate Studies Postdoctoral Fellows Prospective Postdoctoral Fellows. Prospective Postdoctoral Fellows. * ... Dalhousie University Faculty of Graduate Studies Room 314, Henry Hicks Academic Administration Building. Halifax, Nova Scotia, ... Dalhousie University Faculty of Graduate Studies Room 314, Henry Hicks Academic Administration Building. Halifax, Nova Scotia, ...
You are here: CSU, Chico , Study Abroad , Prospective Students. Prospective Students. Congratulations on taking the first step ... attended a Study Abroad Information Session and meet with our country-specific Peer Advisors and/or study abroad advisor in ... After that, you can begin to explore the many other pages about where to go, why to go, and what you can study while abroad. ... By studying abroad, you are joining a community of students that make up less than 10% of college undergraduates nationwide. ...
Accommodation Information for Prospective students. Prospective undergraduates. Accommodation information for prospective ... Prospective postgraduates. Information about accommodation options and application process for postgraduate students ... Imperials impactRead case studies about how Imperial research has made a difference ... International studentsStudents come from over 140 different countries to study at Imperial ...
Welcome, prospective Womens and Gender Studies student! Here youll find resources and information about the program, ... Womens and Gender Studies Program. University of Nebraska-Lincoln. 325 Louise Pound Hall. Lincoln, NE 68588-0319. This is an ... You will also study gender more broadly, which means you will look at feminine, masculine, and queer identities across time and ... With more than 30 majors in the college alone, specialized programs of study to match any interest area, the opportunity for ...
Welcome to the College of Liberal Professional Studies (LPS). We offer a rich portfolio of degree and nondegree options for ... Prepare for graduate study, expand your professional knowledge or explore an area of personal interest with Penns resources ... Welcome to the College of Liberal Professional Studies (LPS). We offer a rich portfolio of degree and nondegree options for ... 2019 College of Liberal and Professional Studies at The University of Pennsylvania ...
STUDY DESIGN: A longitudinal, prospective, observational, cohort study.. OBJECTIVES: To describe the natural history of back ... Back pain during pregnancy: a prospective study.. Kristiansson P1, Svärdsudd K, von Schoultz B. ...
The United Kingdom Prospective Diabetes Study (UKPDS) was the largest clinical research study into diabetes ever conducted at ... The study was conceived by Professor Robert Turner at Oxford University in 1976, conducted in the UK in 1977-1997, and ...
The College of Education Graduate Studies Office provides support for the application through admission process and handles the ... CSULB Home Colleges College of Education Graduate Studies Office Prospective Students Overview ... Prospective Students Overview. Thank you for your interest in Graduate Degree and Advanced Credential programs offered by the ... Interested in Teaching or Doctoral Study?. If you are interested in the Doctor of Education or an initial/preliminary teaching ...
Kenneth Kirsch, the study management team at AXON for study coordination and data management, and medical writer Mark E. Rose, ... Ware MA, Wang T, Shapiro S, Collet JP (2015) Cannabis for the management of pain: assessment of safety study (COMPASS). J Pain ... a prospective cohort study. BMC Health Serv Res 6(1):46. https://doi.org/10.1186/1472-6963-6-46 CrossRefPubMedPubMedCentral ... Although results indicated that the majority of patients included in this study did not reach cutoff scores on the three main ...
We have a global reputation for research that makes a difference. You could be part of it through a PhD or doctoral training centre.
... prospective student! Here youll find resources and information about our undergraduate programs, scholarships and financial ... Major in Classics and Religious Studies Classics and Religious Studies Classical Languages Careers in Classics Scholarships & ... Welcome, prospective student!. Here youll find resources and information about our undergraduate programs, scholarships and ... With over 30 majors in the college alone, specialized programs of study to match any interest area, the opportunity for hands- ...
ACFE online self-study courses feature: 24/7 access to courses through your Internet browser Save time and quickly earn CPE ... Online Self-Study Troubleshooting Guide: Problem: When I attempt to access my courses from "My Online Learning," the course ... ACFE online self-study courses are designed to run on all modern web browsers, but if you encounter a problem that is not ... Solution: You do not have to log in a second time to access your online self-study. You most likely reached the login page ...
... study showed that rhythm-control treatment of patients with atrial fibrillation (AF) offered no survival... ... This study was funded partly by the Swedish Heart-Lung Foundation, but the foundation had no active role in the study. ... a prospective cohort study. Lancet 359(9320):1805-1811PubMedCrossRefGoogle Scholar ... Prospective Randomized Study of Ventricular Failure and the Efficacy of Digoxin) and RADIANCE (Randomized Assessment of Digoxin ...
  • Students pursuing the Bachelor of Arts in International Studies at UNF explore the political and economic structures and cultural dynamics that shape today's global system. (unf.edu)
  • Students learn in context, and put their learning into practice, through study abroad and internships . (unf.edu)
  • The International Studies degree places emphasis on research , as a way to both prepare students for graduate study and to help them develop the information literacy and high-level communication and critical thinking skills needed in today's professional fields. (unf.edu)
  • Students can combine International Studies with other majors to gain specialized knowledge and skills in particular content areas. (unf.edu)
  • The major has no formal prerequisites (some individual courses may), and its flexible structure helps students studying full-time to finish in a timely fashion. (unf.edu)
  • The students in International Studies share an interest in language, culture, and travel. (unf.edu)
  • Because International Studies emphasizes critical thinking, problem-solving skills and cross-cultural competence, the major is sound preparation for a variety of careers, and can be an appropriate major for students who are unsure of the direction they would like to pursue. (unf.edu)
  • Photos: Students presenting at the Spring 2016 and Fall 2016 International Studies Senior Seminar Research Exhibits in the Thomas G. Carpenter Library. (unf.edu)
  • Students who are considering a Film Studies major should consult with the department chair as soon as possible in order to receive advising regarding the major. (wesleyan.edu)
  • To be accepted into the Film Studies major, students are required to have completed two prerequisites, Film 304: History of World Cinema to the 1960s and Film 307: The Language of Hollywood: Styles, Storytelling, and Technology, with a suitable grade in both. (wesleyan.edu)
  • Because of the prerequisites and major requirements, students transferring to Wesleyan beginning their junior year are not able to declare the Film Studies major. (wesleyan.edu)
  • Because communication studies is a generalist degree, students go into a variety of positions/programs upon graduation. (usm.edu)
  • As a truly international university, we welcome applications from prospective postgraduate students anywhere in the world. (tcd.ie)
  • Prospective Students who wish to request a copy of the prospectus by post can email the Academic Registry ( [email protected] ) with their name and postal address or download a digital copy below. (tcd.ie)
  • The regulations which govern students admission to, progression on, and examination on the research register are available in the University of Dublin Calendar Part III and all prospective and current students are strongly recommended to familiarise themselves with these. (tcd.ie)
  • Our students also find it possible to take up part-time work alongside their studies, whether on projects within the Department or more widely. (dur.ac.uk)
  • By studying abroad, you are joining a community of students that make up less than 10% of college undergraduates nationwide. (csuchico.edu)
  • With more than 30 majors in the college alone, specialized programs of study to match any interest area, the opportunity for hands-on experience through our nationally acclaimed undergraduate research program and a campus located at the heart of an innovative college city community of more than 250,000 people, the University of Nebraska-Lincoln offers the ideal Big Ten collegiate experience for students at an affordable cost. (unl.edu)
  • The PRAXIS passing rates for candidates who attended institutions accredited by the National Council for Accreditation of Teacher Education were 'somewhat higher' than for those who did not, despite the fact that SAT scores for entering students are higher in non-NCATE institutions, the study found. (edweek.org)
  • The baccalaureate degree program in Human Development and Family Studies provides students with an understanding of human development and family relationships across the lifespan. (kent.edu)
  • The graduate program in HDFS provides students with advanced knowledge in human development and family studies. (kent.edu)
  • At the master's level, students will develop community research skills and will be prepared for leadership positions within social service agencies, teaching at junior and community colleges or to pursue doctoral level study. (kent.edu)
  • Tokyo Tech's International Office supports various opportunities for graduate students to study abroad. (titech.ac.jp)
  • Many of these agreements include tuition waiver programs that allow Tokyo Tech graduate students to study at a partner university for a semester or a period of up to one year while enrolled at Tokyo Tech. Both Tokyo Tech and the partner university receive and dispatch a designated number of students according to the particular agreement. (titech.ac.jp)
  • TASTE provides financial support to Tokyo Tech students who will participate in a summer intensive language program, such as STEP offered by the University of Washington, before beginning a mid- to long-term study abroad or research program through one of Tokyo Tech's exchange programs. (titech.ac.jp)
  • Prospective students can apply to either or both of the departments. (uchicago.edu)
  • Students who plan to concentrate on Ottoman and Turkish Studies should apply to Ottoman and Turkish Studies program at NELC. (uchicago.edu)
  • Through the university's Division of International Programs, students may take advantage of either short- or long-term study opportunities abroad. (niu.edu)
  • We invite prospective students to contact us at California Western School of Law as they consider where to study law. (cwsl.edu)
  • At California Western we are always eager to meet prospective students, and current students are happy to reach out and welcome you to our community. (cwsl.edu)
  • McCormick and The Graduate School at Northwestern offer many resources to assist international students with their studies, to help ensure they have a rewarding academic and cultural experience. (northwestern.edu)
  • Prospective students are urged to contact the department or program staff or the Office of Graduate Studies with any questions. (northwestern.edu)
  • The objective of this study was to assess sunburn and changes in sunburn and sun behaviors during periadolescence. (aappublications.org)
  • Objective: The present study examined the longitudinal association between personality traits and sleep quality in 4 samples of middle-aged and older adults. (ovid.com)
  • The objective of this study was to assess the efficacy and safety of alfuzosin 10 mg monotherapy or combined antihypertensive medication on blood pressure (BP) in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS) with or without antihypertensive medication. (dovepress.com)
  • OBJECTIVE: To document the prospective, reciprocal relationships among substance use problems, utilization of drug treatment, and predisposing beliefs thought to increase treatment utilization. (rand.org)
  • 3 However, several retrospective studies suggested that cognitive deficits in children with CM are more frequent (occurring in 11%-28% of children with CM) and persist for a far longer time (3-9 years after the CM episode) than neurologic deficits. (aappublications.org)
  • These are some of the big questions addressed at a new exhibition at Palace Green Library , which has been developed by researchers within English Studies. (dur.ac.uk)
  • The researchers looked at records for 160,000 candidates who took the PRAXIS 2 tests, which measure prospective teachers' knowledge of pedagogy and specific subjects, between 1995 and 1997 and had also taken the SAT college-entrance exam in the past 20 years. (edweek.org)
  • In 2012 the researchers obtained a stored blood sample for each individual in the study and tested the samples for 25(OH)D, the marker of vitamin D status. (vitamindcouncil.org)
  • This study will help researchers learn more about non-Hodgkin's lymphoma and Hodgkin's lymphoma and how it is treated in Kenya. (clinicaltrials.gov)
  • The GIGA Doctoral Programme (DP) is a three-year structured programme for junior researchers, in which they can pursue their research and professional development, particularly in the field of comparative area studies (CAS). (jobs.ac.uk)
  • In an excellent example of the kind of comparative effectiveness research needed to distinguish the relative quality of competing treatment approaches, researchers in Alberta, Canada studied the relative costs and benefits of lumbar microdisckectomy and chiropractic spinal manipulation for patients with low back pain and sciatica associated with lumbar disk herniation for whom usual medical care had failed. (chiro.org)
  • Researchers say increased diversity in genomic studies will benefit all, PBS NewsHour reports. (genomeweb.com)
  • Natural News ) A team of European researchers conducted a prospective analysis of the association between the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS) score of foods and cancer risk in a large and diverse European population. (naturalnews.com)
  • A total of 265 patients who were prescribed oral cannabinoid therapy as part of usual medical practice were enrolled into this prospective observational study. (springer.com)
  • Findings from the present study could have implications for clinicians considering the use of cannabinoids for the management of patients with medical conditions. (springer.com)
  • Although results indicated that the majority of patients included in this study did not reach cutoff scores on the three main PPCBU outcomes, our findings suggest that PPCBU should be routinely assessed and monitored over the course of cannabinoid therapy, particularly among patients with a history of psychiatric or substance use problems. (springer.com)
  • The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study showed that rhythm-control treatment of patients with atrial fibrillation (AF) offered no survival advantage over a rate-control strategy. (springer.com)
  • In a subgroup analysis of that study, it was found that digoxin increased the death rate [relative risk (RR) = 1.42), but it was suggested that this may have been attributable to prescription of digoxin for patients at greater risk of death, such as those with congestive heart failure (CHF). (springer.com)
  • Therefore, patients who experienced pain after endodontic treatment and did not require active treatment were excluded from those studies [ 6 ]. (hindawi.com)
  • Patients in Kenya who agree to be in this study will let the resesarchers look at their medical record, follow their normal cancer care, and have blood drawn to look at different proteins and viruses. (clinicaltrials.gov)
  • The aim of this study was to measure actual MAP values among hypotensive patients receiving vasopressor therapy. (plos.org)
  • In the Canadian study, patients receiving chiropractic care averaged 21 visits during their course of care. (chiro.org)
  • We report a prospective study of the outcome of clinically diagnosed infections in patients presenting to UK general practitioners. (prohealth.com)
  • Questionnaires assessing fatigue and psychiatric morbidity were sent to all patients aged 18-45 years in the study practices. (prohealth.com)
  • In a prospective study published this month, patients with cancer of unknown primary who were tested using BioTheranostics' CancerType ID assay, and who then received chemotherapy specific to their predicted tumor of origin, survived longer on average than expected for standard CUP treatment. (genomeweb.com)
  • During study periods, 2,262 patients with ILI were registered. (greenmedinfo.com)
  • This study shows that alfuzosin 10 mg is effective and well tolerated in patients with BPH/LUTS with or without antihypertensive medications. (dovepress.com)
  • The intent of the editorial was to voice caution about the indiscriminate use of quinine for idiopathic muscle cramps in older patients, not to limit its use for patients with conditions such as amyotrophic lateral sclerosis who were excluded from the study of Garrison et al. (cmaj.ca)
  • patients were selected from the pediatric wards of two hospitals in Fortaleza (Hospital Universitário Walter Cantídio-HUWC and Hospital Infantil Albert Sabin-HIAS) from the first oxacillin prescription with a prospective cohort study between October, 2000 and July, 2001 (HUWC) and July/2001 and March, 2002 (HIAS). (scielo.br)
  • BARCELONA - Results of a study presented at European Society of Sports Traumatology, Knee Surgery and Arthroscopy Congress, here, showed patients who participated in sports before total knee arthroplasty were able to participate in sports postoperatively and in some cases, patients were more active in sports after surgery. (healio.com)
  • Caroline Hepperger, MSc, presented results of a prospective study she and her colleagues conducted to evaluate sports behavior preoperatively and postoperatively in 180 patients who underwent cemented cruciate-retaining total knee arthroplasty (TKA). (healio.com)
  • This study documented that patients were not only able to maintain, but to increase activity following surgery. (healio.com)
  • Of the 3396 patients with maxillofacial fractures admitted within the study period, 114 (3.3%) were children aged 15 years and younger, with a male/female ratio of 2.6:1. (uva.nl)
  • All patients who had inpatient surgery at the Austin and Repatriation Medical Centre between December 1998 and March 1999, and remained in hospital for 48 hours or more after surgery, were included in our study. (mja.com.au)
  • Demographic and logistic data were collected for all patients at the time of inclusion in the study (age, sex, surgical specialty of admission, ward, scheduled or unscheduled status of surgery, planned ICU admission). (mja.com.au)
  • Interested in Teaching or Doctoral Study? (csulb.edu)
  • I gained invaluable classroom experience that enabled me to move seamlessly from doctoral study to professional life. (rochester.edu)
  • The Q test and I(2) statistic were used to examine between-study heterogeneity. (nih.gov)
  • Fixed or random effects models were selected based on study heterogeneity. (nih.gov)
  • Mesoscale studies have revealed new understanding of how soil moisture heterogeneity influences the development of convective storms over the course of the diurnal cycle. (hindawi.com)
  • A random effects model was used and between studies heterogeneity was estimated with I 2 . (frontiersin.org)
  • The CSU, Chico Study Abroad Office is excited to help you through this process. (csuchico.edu)
  • After that, you can begin to explore the many other pages about where to go, why to go, and what you can study while abroad. (csuchico.edu)
  • Once you have done all of your research, attended a Study Abroad Information Session and meet with our country-specific Peer Advisors and/or study abroad advisor in order to select a specific program . (csuchico.edu)
  • When studying abroad in Tanzania with SFS, you can expect to have a very unique and a once-in-a-lifetime study abroad experience. (fieldstudies.org)
  • General information about several of the programs and scholarships for studying abroad can be found below. (titech.ac.jp)
  • For a complete list of programs and information about each one, please visit Study Abroad . (titech.ac.jp)
  • Film studies faculty will evaluate applications based on performance in film studies classes (including but not limited to grades) and any other factors deemed pertinent. (wesleyan.edu)
  • The Faculty of Management Studies focuses on management education more than just business management. (fms.edu)
  • If you've been wondering whether Antioch University New England's Environmental Studies graduate programs are right for you, we welcome you to attend our webinar, meet with faculty, and discover what makes AUNE such a unique place. (antioch.edu)
  • Faculty members in Ottoman and Turkish Studies are affiliated with either the Department of Near Eastern Languages and Civilizations (NELC) or the History Department (or both). (uchicago.edu)
  • In cooperation with International Programs, the School of Art has offered foreign study tours each year, directed by faculty members in art. (niu.edu)
  • The aim of this study is to assess the prevalence of uncontrolled and partly controlled asthma in Italy using a patient-based tool such as Asthma Control Test. (clinicaltrials.gov)
  • The aim of this study was to assess the pattern and complications of PIVCs at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia. (dovepress.com)
  • The various models for impact assessment studies can be considered the countries to assess the scenarios. (who.int)
  • This webinar will review a recent study that applied whole-genome sequencing and optical genome mapping to identify a large number of previously undetected somatic structural variants in leukemia samples. (genomeweb.com)
  • In seasonal-interannual West African climate studies, the latest evidence from satellite data analyses and modeling studies confirm that the West African region has a climate which is particularly sensitive to land surface processes and there is a strong coupling between land surface processes and regional climate at intraseasonal/seasonal scales. (hindawi.com)
  • Other studies have examined the influence of social support on depression scores in peripartum mothers by multiple linear regression analyses. (nature.com)
  • A prospective, population-based study was conducted in fifth-grade children (∼10 years of age) from Framingham, Massachusetts. (aappublications.org)
  • The Study of Nevi in Children is a prospective population-based study exploring the natural history of nevi in periadolescence. (aappublications.org)
  • Using data from a large, population based prospective study of reproductive health among women textile workers in Anhui, China, we investigated whether a woman's perceived stress in one menstrual cycle was independently associated with the risk of dysmenorrhoea in the following cycle. (bmj.com)
  • Recently, total cancer risk was reported to be modestly increased in women and men with elevated levels of fasting glucose in a very large cohort study of 1.3 million Korean men and women with 53,833 incident cases of cancer ( 3 ). (diabetesjournals.org)
  • If you would like to visit SUNY Oswego and take a tour of the Communication Studies facilities, please refer to the schedules listed on the Undergraduate Admissions Office website . (oswego.edu)
  • This study confirms some risk factors for DSP found in crosssectional studies and suggests a strong relationship between hypertension and DSP. (diabetesjournals.org)
  • The study also suggests that only a small minority of participating firms, nine percent, bother to use an auto-attendant or answering service to greet callers outside of normal business hours. (findlaw.com)
  • PubMed and Embase databases were searched to identify all related prospective cohort studies. (nih.gov)
  • Eligible studies were identified by searching the PubMed and EMBASE databases for all articles published through June 2013 and reviewing the reference lists of the retrieved articles. (cambridge.org)
  • The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. (clinicaltrials.gov)
  • This study is part of a comprehensive assessment of the validity of FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels in Europe. (naturalnews.com)
  • These features are particularly problematic in retrospective and cross-sectional studies, in which the validity of stress and dysmenorrhoea data depends on a subject's ability to recall both events accurately. (bmj.com)
  • To address these issues and to obtain a robust estimate of the frequency of cognitive deficits in children with CM, we conducted a prospective study of cognitive function in the key cognitive areas of working memory, attention, and learning in Ugandan children (5-12 years of age) with CM, children with UM, and healthy community children (CC). (aappublications.org)
  • Data from this longitudinal study were analyzed using cross-lagged panel models, and structural equation modeling techniques were used to estimate the prospective, reciprocal relationships among these four variables in each of the two samples, while controlling for several covariates. (rand.org)
  • The media computer science Bachelor's program combines studying computer science with learning about digital media, human-computer interaction, computer graphics, natural language processing and digital networks. (uni-stuttgart.de)
  • In the consecutive geodesy and geoinformatics engineering Master's study program you will intensify the academic qualifications you acquired during your Bachelor's studies. (uni-stuttgart.de)
  • however, there were insufficient events for studying survivors of rarer cancers or identifying risk factors for specific second cancers. (aacrjournals.org)
  • Pooling data from cohort studies to investigate nontreatment risk factors for second primary cancers seems feasible but there are important methodologic issues-some of which are barriers to specific research questions-that require special attention. (aacrjournals.org)
  • These findings have not been confirmed in prospective studies, and it is not known whether the predictive power of microalbuminuria is independent of other major cardiovascular risk factors. (diabetesjournals.org)
  • There are two main areas of communication: a social scientific approach to the study of human communication (quantitative and qualitative studies) and a humanistic/rhetorical approach (study of public persuasive messages). (usm.edu)
  • Prospective and retrospective cohort studies have higher accuracy and higher efficiency as their respective main advantages. (nih.gov)
  • The idea that chronic fatigue has an infectious origin has become popular, but the main evidence for such an association has come from retrospective case-control studies, which are subject to ascertainment bias. (prohealth.com)
  • On sensitivity analysis, stratification by gender differences, follow-up duration, and region where study was conducted did not alter the main conclusion. (frontiersin.org)
  • Subjects with sexual adverse events during the double blind phase will continue to be followed at scheduled study visits until resolution of the adverse event or at a visit 6 months after the last dose of study medication, whichever is sooner. (clinicaltrials.gov)
  • In addition, the case subjects studied were those who could be found at the time of follow-up assessment. (aappublications.org)
  • To perform a comprehensive clinicopathological study in these subjects. (clinicaltrials.gov)
  • This study pooled data from two large prospective trials on 10 kHz spinal cord stimulation (10 kHz SCS) in subjects with chronic low back pain and/or leg pain and performed post hoc analysis on changes in opioid dosage 12 months post 10 kHz SCS treatment. (nature.com)
  • The type of dietary questionnaire used varied according to study centers and included: Self- or interviewer-administered semi-quantitative food frequency questionnaires (FFQs) with an estimation of individual average portions or with the same standard portion assigned to all subjects, or diet history questionnaires combining an FFQ and 7-day dietary records. (naturalnews.com)
  • We identified four prospective cohorts for a total of 105,999 subjects and 5,059 cases of new onset HF. (frontiersin.org)
  • This prospective observational trial investigated effects and safety of periodic fasting in subjects with and without type 2 diabetes mellitus (T2DM). (mdpi.com)
  • 1125 subjects having inpatient surgery during the study period. (mja.com.au)
  • Previous studies have investigated psychopathological or psychosocial factors that may be associated with postpartum depression. (nature.com)
  • Observational studies have shown lymphopenia to be associated with risk of cardiovascular disease, 1 - 5 cancer, 6 - 11 liver disease (including alcohol abuse disorders) 12 , 13 and systemic autoimmune disease. (cmaj.ca)
  • In the comment section of a recent Vitamin D Council review of a study that showed no link between vitamin D and pancreatic cancer , Dr. William Grant pointed out that a major limitation of prospective vitamin D studies is the lag time between the vitamin D measurement and the event of interest. (vitamindcouncil.org)
  • The trial was a prospective, non-randomized case-control study, with a primary endpoint of detecting prostate cancer vs no cancer and a secondary endpoint, differentiating between aggressive and non-aggressive cancer. (businesswire.com)
  • The purpose of the study was to evaluate the association of comorbidities on breast cancer survivors' quality of life. (mdpi.com)
  • Many of the studies evaluating sunburning rates in adolescents have been cross-sectional designs, and are subject to limitations. (aappublications.org)
  • It houses the internationally unique Centre for Dutch and Flemish Studies and the Centre for Luxembourg Studies and supplies the Directors of the University's interdisciplinary Research Centres in Nineteenth-Century Studies, Gender Studies in Europe, and Dutch Studies. (sheffield.ac.uk)
  • This study was funded by the CRVOI (Centre de Recherche et de Veille sur les maladies émergentes dans l'Océan Indien), Institut Pasteur, Inserm (Institut National de la Santé et de la Recherche Médicale), Labex IBEID, Fondation pour la Recherche Médicale, BNP-Paribas Foundation and Mairie de Paris. (plos.org)
  • Visit the graduate program page for more details about advanced degrees in Human Development and Family Studies. (kent.edu)
  • visit our Facebook page for news and updates (Southern Miss Department of Communication Studies). (usm.edu)
  • Professor Cawsey is hosted by the Department of English Studies and St Cuthbert's Society. (dur.ac.uk)
  • Meet the Environmental Studies Department, from home! (antioch.edu)
  • The Department of Communication Studies at the University of Michigan is amongst the leading departments in the field, at one of the top-ranked universities in the world. (umich.edu)
  • On behalf of the Department of Communication Studies at the University of Michigan, we look forward to working with you! (umich.edu)