A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.
A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)
A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.
A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.
Substances that provide protection against the harmful effects of freezing temperatures.
Uptake of substances through the SKIN.
Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.
4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.
The presence of free HEMOGLOBIN in the URINE, indicating hemolysis of ERYTHROCYTES within the vascular system. After saturating the hemoglobin-binding proteins (HAPTOGLOBINS), free hemoglobin begins to appear in the urine.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
The application of suitable drug dosage forms to the skin for either local or systemic effects.
Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as EPOXY RESINS.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.
Propylene or propene polymers. Thermoplastics that can be extruded into fibers, films or solid forms. They are used as a copolymer in plastics, especially polyethylene. The fibers are used for fabrics, filters and surgical sutures.
The chemical and physical integrity of a pharmaceutical product.
Unsaturated hydrocarbons of the type Cn-H2n, indicated by the suffix -ene. (Grant & Hackh's Chemical Dictionary, 5th ed, p408)
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794)
Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
The first digit on the radial side of the hand which in humans lies opposite the other four.
A country consisting of the eastern half of the island of New Guinea and adjacent islands, including New Britain, New Ireland, the Admiralty Islands, and New Hanover in the Bismarck Archipelago; Bougainville and Buka in the northern Solomon Islands; the D'Entrecasteaux and Trobriand Islands; Woodlark (Murua) Island; and the Louisiade Archipelago. It became independent on September 16, 1975. Formerly, the southern part was the Australian Territory of Papua, and the northern part was the UN Trust Territory of New Guinea, administered by Australia. They were administratively merged in 1949 and named Papua and New Guinea, and renamed Papua New Guinea in 1971.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
The articulations between the CARPAL BONES and the METACARPAL BONES.
An amidohydrolase that removes intact asparagine-linked oligosaccharide chains from glycoproteins. It requires the presence of more than two amino-acid residues in the substrate for activity. This enzyme was previously listed as EC
The maintenance of certain aspects of the environment within a defined space to facilitate the function of that space; aspects controlled include air temperature and motion, radiant heat level, moisture, and concentration of pollutants such as dust, microorganisms, and gases. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A telecommunication system combining the transmission of a document scanned at a transmitter, its reconstruction at a receiving station, and its duplication there by a copier.

Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway. (1/714)

FTY720 is a novel immunosuppressive drug derived from a metabolite from Isaria sinclairii that is known to induce apoptosis of rat splenic T cells. In this study, we examined the intracellular signaling pathway triggered by FTY720. Treatment of human Jurkat T lymphocytes with FTY720-induced apoptosis characterized by DNA fragmentation. The same treatment induced activation of protein kinases such as c-Jun NH2-terminal kinase (JNK), p38/CSBP (CSAID-binding protein), and a novel 36-kDa myelin basic protein (MBP) kinase, but not extracellular signal-regulated kinase (ERK). Pretreatment of Jurkat cells with DEVD-CHO blocked FTY720-induced DNA fragmentation as well as the activation of p38/CSBP. However, DEVD-CHO treatment failed to inhibit FTY720-induced activation of JNK and the 36-kDa MBP kinase. We have also demonstrated that activation of the ERK signaling pathway completely suppressed the FTY720-induced apoptotic process including activation of caspase 3 and activation of JNK and the 36-kDa MBP kinase. Furthermore, transient expression of constitutively active mitogen-activated protein kinase/ERK kinase (MEK) protected the cells from FTY720-induced cell death. The effect of MEK was canceled by coexpression of a mitogen-activated protein kinase phosphatase, CL100. These results indicate that JNK and p38 pathways are differentially regulated during FTY720-induced apoptosis and that activation of ERK pathway alone is sufficient to cancel the FTY720-induced death signal.  (+info)

Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action. (2/714)

Felbamate is an anticonvulsant used in the treatment of seizures associated with Lennox-Gastaut syndrome and complex partial seizures that are refractory to other medications. Its unique clinical profile is thought to be due to an interaction with N-methyl-D-aspartate (NMDA) receptors, resulting in decreased excitatory amino acid neurotransmission. To further characterize the interaction between felbamate and NMDA receptors, recombinant receptors expressed in Xenopus oocytes were used to investigate the subtype specificity and mechanism of action. Felbamate reduced NMDA- and glycine-induced currents most effectively at NMDA receptors composed of NR1 and NR2B subunits (IC50 = 0.93 mM), followed by NR1-2C (2.02 mM) and NR1-2A (8.56 mM) receptors. The NR1-2B-selective interaction was noncompetitive with respect to the coagonists NMDA and glycine and was not dependent on voltage. Felbamate enhanced the affinity of the NR1-2B receptor for the agonist NMDA by 3.5-fold, suggesting a similarity in mechanism to other noncompetitive antagonists such as ifenprodil. However, a point mutation at position 201 (E201R) of the epsilon2 (mouse NR2B) subunit that affects receptor sensitivity to ifenprodil, haloperidol, and protons reduced the affinity of NR1-epsilon2 receptors for felbamate by only 2-fold. Furthermore, pH had no effect on the affinity of NR1-2B receptors for felbamate. We suggest that felbamate interacts with a unique site on the NR2B subunit (or one formed by NR1 plus NR2B) that interacts allosterically with the NMDA/glutamate binding site. These results suggest that the unique clinical profile of felbamate is due in part to an interaction with the NR1-2B subtype of NMDA receptor.  (+info)

A Saprolegnia parasitica challenge system for rainbow trout: assessment of Pyceze as an anti-fungal agent for both fish and ova. (3/714)

A reproducible Saprolegnia parasitica spore delivery system was developed and demonstrated to be effective in providing a sustained spore challenge for up to 10 d. Treatment of rainbow trout with slow-release intraperitoneal implants containing cortisol resulted in chronically elevated blood cortisol levels and rendered the fish susceptible to infection by S. parasitica when exposed to the spore challenge. Sham-implanted fish were not susceptible to infection. Bronopol (2-bromo-2-nitro-propane-1,3-diol), formulated as Pyceze, was effective in protecting predisposed fish from infection by S. parasitica when administered as a daily bath/flush treatment at concentrations of 15 mg l-1 and greater. Pyceze was also demonstrated to protect fertilised rainbow trout ova from S. parasitica challenge when administered as a daily bath/flush treatment at concentrations of between 30 and 100 mg l-1. Pyceze appears to qualify as a safe and effective replacement for malachite green and formalin in the prevention of fungal infections in the aquaculture environment.  (+info)

Development and testing of a microbiological assay to detect residual effects of disinfectant on hard surfaces. (4/714)

We describe a glucuronidase bioassay for detecting residual bactericidal activity from the use of disinfectants on hard surfaces; in this assay we used formaldehyde, ethanol, isopropanol, chlorine, and a commercial preparation containing 2-bromo-2-nitro-1, 3-propanediol. Chlorine and the commercial preparation showed bactericidal activity (53.5% and 98.2%, respectively) for a week after disinfection.  (+info)

Assessment of adult and neonatal reproductive parameters in Sprague-Dawley rats exposed to propylene glycol monomethyl ether vapors for two generations. (5/714)

This study evaluated propylene glycol monomethyl ether (PGME) in a rat 2-generation reproduction study, which included non-traditional study end points, such as sperm count and motility, developmental landmarks, estrous cyclicity, and weanling organ weights. Groups of 30 male and 30 female Sprague-Dawley rats (6-weeks-old) were exposed to 0, 300, 1000, or 3000 ppm of PGME vapors via inhalation for 6 hours/day, 5 days/week prior to mating, and 6 hours/day, 7 days/week during mating, gestation, and lactation, for 2 generations. These concentrations corresponded to estimated oral equivalent doses of 0, 396, 1325, or 3974 mg/kg/day. At 3000 ppm, toxicity in the P1 and P2 adults was marked, as evidenced by sedation during and after exposure, and mean body weights which were as much as 21% lower than controls. This marked parental toxicity was accompanied by lengthened estrous cycles, decreased fertility, decreased ovary weights, and histologic ovarian atrophy in maternal rats. In the offspring from these dams, decreased body weights, reduced survival and litter size, slight delays in puberty onset, and histologic changes in liver and thymus in the F1 and F2 offspring were observed. The nature of the reproductive/neonatal effects and their close individual animal correlation with decreased maternal body weights suggested that these effects were secondary to general toxicity and/or nutritional stress. No such reproductive/neonatal effects were observed at 1000 ppm, a concentration which caused less marked, but significant body weight effects without sedation. There were no treatment-related effects of any kind noted at 300 ppm of PGME. Therefore, the no-observable-effect level (NOEL) for reproductive/neonatal effects was 1000 ppm, and that for parental toxicity was 300 ppm.  (+info)

FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation. (6/714)

Background-Effective immunosuppression is a critical determinant of organ and patient survival in cardiac transplantation. The present study was designed to determine the potency of FTY720, a new synthesized immunosuppressant, and examine its clinical potential as an immunosuppressant. Methods and Results-Hearts of DBA/2 mice were transplanted heterotopically in C57BL/6 mice. Recipients were treated with oral FTY720 in doses of 0.3, 1, 3, or 10 mg. kg(-1). d(-1) or with 40 mg. kg(-1). d(-1) of cyclosporin A (CsA) as a comparative treatment. The median graft survival time (MST) was significantly prolonged by treatment with FTY720 10 mg. kg(-1). d(-1). MST was not prolonged by FTY720 1 mg. kg(-1). d(-1) or CsA. However, FTY720 1 mg. kg(-1). d(-1) combined with CsA 40 mg. kg(-1). d(-1) resulted in a significant prolongation of MST. Histopathological studies performed 5 days after transplantation demonstrated remarkable suppression of inflammatory response by treatment with FTY720 10 mg. kg(-1). d(-1). Interleukin (IL)-2 and interferon (IFN)-gamma production was not suppressed; however, cytotoxic T lymphocyte activity was strongly suppressed in vitro. In addition, IL-2-stimulated T-cell proliferation and class I and class II MHC antigen expression on IFN-gamma-stimulated macrophages were strongly inhibited by FTY720. Histopathological studies 60 days after transplantation (DBA/2-B10.D2) demonstrated a beneficial effect on graft atherosclerosis. Conclusions-FTY720 promoted long-term cardiac graft survival and strongly inhibited the progression of graft atherosclerosis. These observations suggest that FTY720 has a promising clinical potential in cardiac transplantation.  (+info)

Short-chain alcohols promote an early stage of membrane hemifusion. (7/714)

Hemifusion, the linkage of contacting lipid monolayers of two membranes before the opening of a fusion pore, is hypothesized to proceed through the formation of a stalk intermediate, a local and strongly bent connection between membranes. When the monolayers' propensity to bend does not support the stalk (e.g., as it is when lysophosphatidylcholine is added), hemifusion is inhibited. In contrast, short-chain alcohols, reported to affect monolayer bending in a manner similar to that of lysophosphatidylcholine, were here found to promote hemifusion between fluorescently labeled liposomes and planar lipid bilayers. Single hemifusion events were detected by fluorescence microscopy. Methanol or ethanol (1.2-1.6 w/w %) added to the same compartment of the planar bilayer chamber as liposomes caused a 5-50 times increase in the number of hemifusion events. Alcohol-induced hemifusion was inhibited by lysophosphatidylcholine. Promotion of membrane hemifusion by short-chain alcohol was also observed for cell-cell fusion mediated by influenza virus hemagglutinin (HA). Alcohol promoted a fusion stage subsequent to the low pH-dependent activation of HA. We propose that binding of short-chain alcohol to the surface of membranes promotes hemifusion by facilitating the transient breakage of the continuity of each of the contacting monolayers, which is required for their subsequent merger in the stalk intermediate.  (+info)

A phase I and pharmacological study of protracted infusions of crisnatol mesylate in patients with solid malignancies. (8/714)

This Phase I and pharmacological study was performed to assess the feasibility of administering the polycyclic aromatic hydrocarbon crisnatol in increasingly prolonged continuous i.v. infusions to patients with advanced solid malignancies. The study also sought to characterize the-principal toxicities of crisnatol on this schedule, to recommend doses for subsequent disease-directed studies, and to characterize possible associations between pharmacological parameters and toxicity. Sixteen patients were treated with 40 courses of crisnatol administered as a continuous i.v. infusion. The initial dose-schedule was 750 mg/m2/day for 6 days, and the duration of the infusion was to be progressively increased by 3-day increments to 9, 12, 15, 18, and 21. Courses were to be repeated every 4 weeks. Moderate to severe central nervous system (CNS) toxicity precluded the administration of crisnatol 750 mg/m2/day for longer than 6 days, and, therefore, the dose of crisnatol was reduced to 600 mg/m2/day. At this dose, three of five patients receiving a 12-day infusion experienced dose-limiting toxicity, which consisted of pulmonary thromboembolism (two patients) and grade 4 thrombocytopenia (one patient). None of the six patients completing a 9-day infusion at 600 mg/m2/day developed dose-limiting toxicity during the first or second course of crisnatol. At this dose level, the plasma concentrations at steady state (Css) averaged 1607.8+/-261.1 ng/ml, which exceeds minimal inhibitory concentrations for most tumors in vitro (1000 ng/ml). In fact, the administration of crisnatol at a dose of 600 mg/m2/day for 9 days resulted in the longest duration that biologically relevant plasma crisnatol concentrations have been sustained. Plasma Css values were significantly higher in patients who experienced severe CNS toxicity compared with those who did not (2465.3+/-1213.5 versus 1342+/-447.3 ng/ml; P = 0.04). There were no relationships evident between the clearance of crisnatol and indices reflecting renal and hepatic functions. One patient with a glioblastoma multiforme experienced a partial response lasting 14 months. The relative lack of intolerable CNS toxicity at the recommended dose for Phase II studies of crisnatol, 600 mg/m2/day for 9 days, as well as the magnitude of the Css values achieved and the antitumor activity observed at this dose, are encouraging. However, the mechanisms for the apparently increased thrombogenicity observed in this trial are unclear and require further elucidation.  (+info)

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[150 Pages Report] Check for Discount on 2016 Propylene Glycol monomethyl Ether propinate (PMP) Industry Market Report report by Prof Research. The Global and Chinese Propylene Glycol monomethyl Ether propinate (PMP)...
Excellent quality PGME chemical from HENAN PROSPER CHEMICALS. Extensive Selection! Global distributors. Featured Products. Industry Leader. HENAN PROSPER CHEMICALS propylene glycol monomethyl ether, reliable chemical products supplier in China. 15+ years history.
Press Release issued Sep 21, 2016: Firstly, Dipropylene glycol (DPG) Market report provides a basic overview of the Dipropylene glycol (DPG) industry including definitions, classifications, applications and Dipropylene glycol (DPG) industry chain structure. Global Dipropylene glycol (DPG) Market analysis is provided for the international market including development history, Dipropylene glycol (DPG) industry competitive landscape analysis, and major regions development status on Dipropylene glycol (DPG) Market scenario.
PMP is excellent industrial solvent with low toxic, it has strong solubility for polar and non-polar materials, which can be used for advanced paints, printing inks as well as some other polymers, including amido, methyl ester, ethyl, polyester, cellulose acetate, glycol acid resin, crylic acid resin, epoxy resin and nitrocellulose etc ...
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Introduction: Fingolimod, a sphingosine-1-phosphate receptor agonist, is used for the treatment of multiple sclerosis and exerts anti-inflammatory and antiapoptotic properties.. Hypothesis: We hypothesized that sphingosine-1-phosphate receptor activation with fingolimod during circulatory arrest inhibits apoptosis and inflammation leading to increased myocardial and cerebral functions after reperfusion with extracorporeal life support (ECLS).. Methods and Results: Ventricular fibrillation (VF) was induced in male Wistar rats. After 10 min of untreated VF, veno-arterial ECLS was instituted for 60 minutes. At the beginning of ECLS animals randomly received fingolimod or saline (control). Restoration of spontaneus circulation and 24 hours survival were higher in rats that received fingolimod (p = 0.03). Fingolimod treatment activated the cardioprotective reperfusion injury salvage kinase and survivor activating factor enhancement pathways leading to decreased cardiomyocyte apoptosis and reduced ...
Global Dipropylene Glycol (DPG) Sales Market by Manufacturers, Types, Regions and Application & Forecast to 2025(Shopping-NewsWire.com, January 12, 2018 ) Global Dipropylene Glycol (DPG) Sales Market report is replete with detailed analysis from a thorough research, especially on questions that bo
[104 Pages Report] Check for Discount on Global Dipropylene Glycol (DPG) Market Research Report 2017 report by QYResearch Group. In this report, the global Dipropylene Glycol (DPG) market is...
Oral fingolimod (Gilenya) in relapsing MS: impact on health-related quality of life in a phase II study Summary: This phase II, placebo controlled study in relapsing MS from Spain reports on the effects of treatment with fingolimod (Gilenya) on patients ...
In this study, pumice stone (PS), which is a vastly available material in Turkey, was evaluated as an alternative immobilization material in comparison to other commercially available immobilization materials such as glass beads and polyurethane foam. All immobilized bioreactors resulted in much better 1,3-propanediol production from waste glycerol in comparison to the suspended cell culture bioreactor. It was also demonstrated that the locally available PS material is as good as the commercially available immobilization material. The maximum volumetric productivity (8.5 g L-1 h(-1)) was obtained by the PS material, which is 220 % higher than the suspended cell system. Furthermore, the immobilized bioreactor system was much more robust against cell washout even at very low hydraulic retention time values. ...
PubMed journal article: Oral fingolimod (FTY720) for relapsing multiple sclerosis. Download Prime PubMed App to iPhone, iPad, or Android
Pulmonary tissue damage resulting from influenza virus infection is caused by both the cytolytic activity of the virus and the host immune response. Immune-mediated injury results from T cell-mediated destruction of virus-infected cells and by release of cytokines and chemokines that attract polymorphonuclear leukocytes (PML) and macrophages to the infected site. The cytokines/chemokines potentiate dendritic cell (DC) activation and T cell expansion, which further enhances local damage. Here we report that immune modulation by local administration to the respiratory tract of sphingosine analog AAL-R significantly dampens the release of cytokines and chemokines while maintaining protective neutralizing antibody and cytotoxic T cell responses. As a result there was a marked reduction of infiltrating PML and macrophages into the lung and resultant pulmonary tissue injury. DC maturation was suppressed, which limited proliferation of specific antiviral T cells in the lung and draining lymph nodes. ...
Less] Identification and Use: Dipropylene Glycol is used as medication, as an antifreeze agent, in air sanitation, . . . [More] Identification and Use: Dipropylene Glycol is used as medication, as an antifreeze agent, in air sanitation, and as a stabilizer in cosmetic preparations. It is also used as an intermediate for polyester resins, solvent extraction of aromatic hydrocarbons, steam set printing inks, stabilizer in cosmetics. As an inert ingredient, dipropylene glycol facilitates delivery of formulated pesticide chemical products that are used as herbicides, fungicides, insecticides, growth regulators and attractants on various commodities. It is also used in targeting odor-causing bacteria, animal pathogenic bacteria (G- and G+ vegetative), and animal viruses. Human Toxicity Studies: Repeated application of a shaving preparation containing 7.2% dipropylene glycol did not induce sensitization in 50 subjects when applied in 24/48 hr (presumably covered) patches, 3 days/wk for 3 weeks, ...
This Retrospective,Multicenter,Observational,real world study to evaluate effect of Fingolimod treatment on MRI brain in patients with Multiple Sclerosis
DPNB (DIPROPYLENE GLYCOL N-BUTYL ETHER) - Brenntag product information page Brenntag is Beneluxs leading distributor and exporter of industrial chemicals and specialties, located in Belgium (Deerlijk, Antwerpen & Mouscron) and the Netherlands (Dordrecht, Loosdrecht, Zwijndrecht, Moerdijk, Rotterdam, Enschede).
(KudoZ) Polish to English translation of eter metylowy glikolu dipropylenowego: dipropylene glycol methyl ether [Chemistry; Chem Sci/Eng (Tech/Engineering)].
Dipropylene Glycol is used heavily in the production of plasticisers but mostly known for its use as a fragrance fixative and carrier in perfumes, soaps and cosmetic products.
Description Dipropylene glycol is a mixture of three isomeric chemical compounds 4-oxa-2 6-heptandiol 2--propan-1-ol and 2--propan-1-ol It is a
Make your fragrance skin safe or make incense with our Dipropylene Glycol (DPG). It is also suitable for potpourri, burners and is an excellent solvent for many organic materials
Description: Blood lymphocyte numbers, essential for the development of efficient immune responses, are maintained by recirculation through secondary lymphoid organs. We show that lymphocyte trafficking is altered by the lysophospholipid sphingosine-1-phosphate (S1P) and by a phosphoryl metabolite of the immunosuppressive agent FTY720. Both species were high-affinity agonists of at least four of the five S1P receptors. These agonists produce lymphopenia in blood and thoracic duct lymph by sequestration of lymphocytes in lymph nodes, but not spleen. S1P receptor agonists induced emptying of lymphoid sinuses by retention of lymphocytes on the abluminal side of sinus-lining endothelium and inhibition of egress into lymph. Inhibition of lymphocyte recirculation by activation of S1P receptors may result in therapeutically useful immunosuppression. ...
Pharmacokinetic Analysis of β-Glucan After Administration of PGG-Glucan, a Novel Immunomodulator Being Developed for the Treatment of Non-Small Cell Lung Cancer ...
Effects of a novel immunomodulator in HIV infected individuals. Международная деятельность. Экомед
[2-Amino-4-(4-octylphenyl)butyl] dihydrogen phosphate | C18H32NO4P | CID 10150171 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Fingolimod, a novel sphingosine 1-phosphate receptor agonist, is indicated for the treatment of patients with relapsing- remitting multiple sclerosis. In clinical trials, oral fingolimod was more...
To produce 1,3-propanediol (1,3-PD) from crude glycerol, cultivation conditions were optimized by response surface methodology (RSM) based on a 25 factorial central composite design (CCD). RSM was ado
Fingolimod (FTY720) is the first of a novel class: sphingosine 1-phosphate (S1P) receptor modulator and is currently in phase 3 clinical trials for multiple sclerosis (MS). FTY720 was first synthesized in 1992 by chemical modification of an immunosuppressive natural product, ISP-I (myriocin). ISP-I …
Basel, September 05, 2017 - Novartis today announced positive topline results from the Phase III PARADIGMS study, investigating the safety and efficacy of oral once-daily fingolimod in children and adolescents (ages 10 to 17) with multiple sclerosis (MS). Data show that oral fingolimod resulted in a significant and clinically meaningful reduction in the number of relapses (annualized relapse rate) in this patient population over a period of up to two years, compared to interferon beta-1a intramuscular injections[1]. The safety profile of fingolimod was consistent with that seen in other clinical trials, with overall more adverse events reported in the interferon group[1]. The PARADIGMS study is the first ever randomized, controlled Phase III study of a disease-modifying therapy (DMT) in pediatric MS[2].. Living with MS is a tremendous challenge at any age. However, its appearance in children and adolescents, when these young individuals should be developing and focusing on their future, can be ...
Background: Sphingosine-1 phosphate (S1P) is a biophospholipid with antiapoptotic properties. Previous experiments suggest protective effects of S1P receptor (S1P-R) agonism against ischemia-reperfusion (I-R) injury in several organs, and also in cardiomyocyte cell culture. Fingolimod (FIN) is the only S1P-R agonist FDA-approved for clinical use in multiple sclerosis. The objective of our study was to determine if S1P-R activation by FIN during ischemia increases myocardial salvage, reduces myocardial infarction (MI) size, and mitigates left ventricular (LV) remodeling in a porcine model of I-R.. Methods: Acute MI was induced in 14 pigs by balloon occlusion of the proximal LAD for 60 min, followed by reperfusion. Animals randomly received FIN 15 minutes prior to reperfusion and then daily for the next 3 days, or saline for controls. Animals were evaluated with cardiac MRI and 3D-echo at 1 week and 1 month post MI. Histology and Western blot analysis were performed after 1 month.. Results: One ...
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Bronopol has been used as a preservative in drugs and cosmetics since 1964. Bronopol has low dermal irritancy at levels commonly used in cosmetics and pharmaceuticals but it is significantly irritating at higher concentrations. Laboratory testing of bronopol indicates a low potential for dermal sensitization; however, a number of case reports demonstrate human allergenic reactions. No reports were identified on the allergenic properties of bronopol for the inhalation route of exposure. In 1983 approximately 5,200 people in the United States were occupationally exposed to bronopol. Current novel uses of bronopol include mold remediation and the sanitizing of ventilation system components. These new applications have the potential to expose vast new populations to the chemical. Since 89 million people in the United States work in indoor environments and 50 million Americans suffer from allergies, it is likely that a sizeable portion of these populations will be exposed to bronopol. This is significant
The U.S. Food and Drug Administration has reviewed Novartis AGs multiple sclerosis drug Gilenya, and concluded that patients whove suffered a heart attack or stroke within the past six months shouldnt take it.. The review came about after a 59-year-old patient died in November, less than 24 hours after taking the first dose of the drug.. Europes drug regulator, the European Medicines Agency, recently requested stronger safety warnings for Gilenya after the agency concluded its review of the drug.. According to Dow Jones Newswires, Gilenya is currently the only oral MS drug on the market, and its recently been dogged by safety concerns.. A European Medicines Agency review of Gilenya states: While no cases of sudden or unexplained death had been reported in clinical studies at the time of its authorization, it was known that Gilenya causes a transient bradycardia (a short-lived decrease in heart rate) and might be associated with atrioventricular block (a type of heart rhythm disorder). ...
Gilenya (fingolimod) is a disease modifying drug for relapsing remitting multiple sclerosis. Learn more about Gilenya in this A-Z entry.
RESULTS:Results showed that fingolimod 0.5 and 1.25mg prolonged time to relapse, with an estimated median time to first relapse of 5.07 years (P=0.0026 vs. IFNβ-1a IM) and 4.11years (P=0.0113), respectively, versus 2.26 years with IFNβ-1a IM. The estimated ratio of observed time to first confirmed relapse to the estimated time had the patient remained on IFNβ-1a IM was 2.09 (95% CI, 1.45-3.04) for switching to fingolimod 0.5mg and 1.84 (95% CI, 1.30-2.65) for switching to fingolimod 1.25mg. ...
Conclusions: The number of patients becoming pregnant during fingolimod therapy remains small and does not permit firm conclusions to be drawn about fetal safety of fingolimod in humans. Given the known risks of teratogenicity in animals and the present data, women of childbearing potential should use effective contraception during fingolimod therapy and for 2 months after discontinuation. (Source: Neurology)
Methods Patients either continued on the fingolimod dose assigned in the core phase (continuous-group c-group) or were re-randomised from placebo to fingolimod (switch-group s-group). Clinical and MRI outcomes (Month 0-24, core/ Month 24-48, extension) for fingolimod 0.5mg are presented for the following high-disease-activity subgroups: Group-1 (n=110), interferon-beta (IFN) therapy in previous year and ≥ relapse in year-1 vs. year-2;; Group-2 (n=106), IFN therapy in previous year+≥1 relapse in year-1 with either ≥1 Gd+ T1 lesion or ≥9 T2 lesions at baseline; Group-3 (n=90), treatment-naïve rapidly evolving severe RRMS patients (≥2 relapses in year-1 and ≥1 baseline Gd+-lesion). ...
Bronopol is a medicine available in a number of countries worldwide. A list of US medications equivalent to Bronopol is available on the Drugs.com website.
Fingolimod is a an immune-migration inhibition agent. This means that rebound can occur when cells come out of their niche where they are supposedly held by loss of sphingosine one phosphate receptor. However when you examine the blood you can not only see that some subset of white cell disappear from the blood, you can also see that in some individuals there is a loss of white blood cells. This study reiterates this issue and says that despite withdrawal of drug there are some people that do not reconstitute their immune system. This would perhaps suggest that fingolimod may be depleting immune stem cells/progenitors and so that people do not reconstitute properly. This is saying that there are actions other than simple blockade of migration and I may suggest that it can kill cells. We know this can happen as there is evidence in the literature, ...
GILENYA (aka fingolimod and FTY720, previously known as Gilenia) was approved by the US FDA on Wed 9/22/10 to treat relapsing forms of MS. It is administered as a once-per-day 0.5mg capsule. Gilenya is the first approved oral disease modifying treatment for MS. Combined data from a Phase II study and two Phase III trials showed that Gilenya reduces relapses, disability progression, MRI lesion activity, and brain atrophy progression (loss of brain tissue). Gilenya is generally safe and well tolerated. One of the possible side effects from this medication is macular edema (fluid swelling of the retina in the back of the eye) that causes blurred vision. This rarely occurs and usually it develops within 3-6 months after starting Gilenya. It will improve with discontinuation of Gilenya. Patients will be required to have an eye exam including a test called optical coherence tomography (OCT) prior to starting Gilenya, and 3-4 months after starting treatment. Patients with diabetes and uveitis are at ...
The purpose of this world-wide prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another disease-modifying therapy, is to further explore the incidence of selected safety- related outcomes and to further monitor the overall safety profile of fingolimod under conditions of routine medical practice ...
The purpose of this world-wide prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another disease-modifying therapy, is to further explore the incidence of selected safety- related outcomes and to further monitor the overall safety profile of fingolimod under conditions of routine medical practice ...
This is the first national study which assessed the cardiac safety of the first dose of Fingolimod (FTY-Gilenya) versus Fingolimod (FTY-Generic) in patients
Fingolimod (FTY720) HCl(フィンゴリモド、Gilenya)は、0.033nMのIC50によるスフィンゴシン1-リン酸(S1P)受容体拮抗剤です。
by Dennis Crouch. Novartis v. Torrent Pharma, Apotex, and Mylan (Fed. Cir. 2017). At the conclusion of its Inter Partes Review (IPR) Trial, the Patent Trial & Appeal Board (PTAB) found all claims of Novartis U.S. Patent No. 8,324,283 invalid as obvious. The PTAB had allowed Novartis to include substitute claims as well, but found those also unpatentable as obvious. On appeal here, the Federal Circuit affirms.. The 283 patent covers a solid combination of a sphingosine-1 phosphate (S1P) receptor agonist (fingolimod) and a sugar alcohol (mannitol). The drug - sold under the trade name Gilenya - is used to treat multiple sclerosis. This is the first oral disease modifying MS drug approved by the FDA and is a big drug with billions in sales each year.. The particular ingredients were already known in the art, and the active ingredient - fingolimod - was already known as useful for treating autoimmune diseases such as MS. However, none of the references brought-together the entire combination in a ...
Guinea pig maximisation test (defined exposure scheme) The sensitising potential of Bronopol (purity 100%) was tested in the guinea pig maximisation test. The study (Unilever Research Laboratory, 1976) followed no guideline as it was conducted in 1976; however the study was conducted according to the acknowledged method of Magnusson and Kligman (1969), which preceeded OECD 406. GLP was not compulsory at the time the study was conducted. The test concentrations selected for induction (intradermal injection and epicutaneous occlusive application) and challenge were chosen on the basis of the results of two preliminary tests (intradermal injection and topical application) conducted each with 4 female animals. The test concentrations for the main sensitisation test were: 0.02% in 0.9% saline for the first induction (intradermal injection), 1.5% in distilled water for the second induction (epicutaneous, occlusive application) and 0.4% in distilled water for challenge. The main test was conducted with ...
Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate, Propylene Glycol Oleate and Propylene Glycol Oleate SE are monoesters of propylene glycol and fatty acids.. SE indicates that it is a self-emulsifying form that contains some sodium and/or potassium oleate. Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Dipelargonate, Propylene Glycol Oleate, Propylene Glycol Dicaprate, Propylene Glycol Diisostearate and Propylene Glycol Dilaurate are diesters of proplyene glycol and fatty acids. The use of the / in the name indicates that the ingredient is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate. In cosmetics and personal care products, Propylene Glycol monoesters and diesters are used in the formulation of moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks.. ...
Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate, Propylene Glycol Oleate and Propylene Glycol Oleate SE are monoesters of propylene glycol and fatty acids.. SE indicates that it is a self-emulsifying form that contains some sodium and/or potassium oleate. Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Dipelargonate, Propylene Glycol Oleate, Propylene Glycol Dicaprate, Propylene Glycol Diisostearate and Propylene Glycol Dilaurate are diesters of proplyene glycol and fatty acids. The use of the / in the name indicates that the ingredient is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate. In cosmetics and personal care products, Propylene Glycol monoesters and diesters are used in the formulation of moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks.. ...
triethylene glycol monomethyl ether chemical properties, What are the chemical properties of triethylene glycol monomethyl ether 112-35-6, What are the physical properties of triethylene glycol monomethyl ether ect.
Viscosities of binary liquid mixtures of some n-alkoxypropanolswith n-alkanols at 298.15 K. Amalendu Pal* & Rekha Gaba. Received 1 August 2006; rerevised 22 August 2007. The viscosities (h) in binary liquid mixtures of (n-alkoxypropanols + methanol, ethanol, or 1-propanol) have been measured as a function of composition using an Ubbelohde viscometer at 298.15 K and atmospheric pressure over the full range of composition. The n-alkoxypropanols are propylene glycol monomethyl ether (1-methoxy-2-propanol), CH3OCH2CH2CH2OH, propylene glycol monoethyl ether (1-ethoxy-2-propanol), C2H5OCH2CH2CH2OH, propylene glycol monopropyl ether (1-propoxy-2-propanol), C3H7OCH2CH2CH2OH, propylene glycol monobutyl ether (1-butoxy-2-propanol), C4H9OCH2CH2CH2OH propylene glycol tert-butyl ether (1-tert-butoxy-2-propanol), CH3CHOHCH3OC(C4H9)3. The h values for each of the mixture studied are positive over the whole mole fraction range. For all the cases, except propylene glycol tert-butyl ether, h increases in a ...
Murphy, CT, Hall, LJ, Hurley, G, Quinlan, A, MacSharry, J, Shanahan, F, Nally, K and Melgar, S (2012) The Sphingosine-1-Phosphate Analogue FTY720 Impairs Mucosal Immunity and Clearance of the Enteric Pathogen Citrobacter rodentium. Infection and Immunity, 80 (8). pp. 2712-2723. ISSN 0019-9567 Full text not available from this repository. (Request a copy ...
4 petri dishes (for storing chips) • small ~6 pieces of the intramedic tubing (ID 0.86mm OD 1.27mm) • razor blades • Nitrile gloves • Biopsy Punches (1.2mm, 1.0mm, 0.75mm diameters) • Stainless steel blunt needle, 16 ½ gauge • Small green needle (21 ½ gauge Becton-Dickinson) • Pieces of scrap PDMS (in small petri dishes on your bench) • Cured PDMS, cut from molds (in 4 petri dishes, covered with tape) • Scotch tape • 1ml syringes with Luer-Lok tips • 4 petri dishes • 4 silicon wafers • SU8-20205 photoresist • SU8 developer (propylene glycol monomethyl ether acetate PGMEA) • Transparency Masks • Wafer Tweezers • Scotch tape • Scissors • Transparency Masks • Aluminum foil • Acetone • Cleanroom wipes (do not shed particles like paper towels or Kim wipes) • HMDS (hexamethyldisilazane) • 5 square glass plates with rounded edges • Lab coat • Hairnets • nitrile glocse • Cleanroom booties • Safety glasses • Sheet protectors for holding ...
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TY - JOUR. T1 - Sphingosine 1-phosphate receptor modulators. T2 - A new class of immunosuppressants. AU - Yopp, Adam C.. AU - Ledgerwood, Levi G.. AU - Ochando, Jordi C.. AU - Bromberg, Jonathan S.. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2006/11. Y1 - 2006/11. N2 - In this review, we summarize how FTY720 came from the lab bench to the bedside by examining its structural similarities to natural occuring sphingosine analogues, the mechanism of action, and clinical applicability to not only transplantation but also autoimmune, oncological, and neurobiological fields. FTY720, a sphingosine 1-phosphate (S1P) analogue, promotes the survival of human and animal allografts by sequestering T lymphocytes within peripheral lymphoid tissue. The mechanism of sequestration is three-fold:(1) T lymphocytes are driven into peripheral lymph nodes in a chemokine dependent manner by FTY720;(2) FTY720 downregulates sphingosine 1-phosphate receptors (S1PRs) on the T lymphocyte ...
The reforming of biomass-derived oxygenates such as ethanol or glycerol has been deeply studied. However, the stability of catalyst formulations developed for glycerol reforming was not the main focus of this development work to date. In the case of propylene glycol, few studies have been addressed to date. Propylene glycol serves as coolant in many mobile applications nowadays and therefore a distribution grid already exists.. The practical processing of larger amounts of polyalcohols such as propylene glycol to synthesis gas for fuel cell applications in reactors larger than laboratory scale suited for distributed applications has not been adequately addressed to date. The current work deals with (a) the development of stable catalyst formulations for propylene glycol reforming and (b) reformer and fuel processor development for the steam reforming of propylene glycol in the power range exceeding 17 kWthermal of the synthesis gas product. A self developed stable catalyst formulation was ...
The purpose of this study was to investigate the biodegradability of propylene glycol in anaerobic conditions by using methanogenic culture. A master reactor was set up to develop a culture that would be acclimated to propylene glycol. After reaching steady-state, culture was transferred to serum bottles. Three reactors with same initial conditions were run for consistency. Propylene glycol was completely biodegradable under anaerobic methanogenic conditions. Semi-continuous reactors operated at a temperature of 35A degrees C had consistently achieved a propylene glycol removal of higher than 95 % based on chemical oxygen demand (COD). It was found that in semi-continuous reactors, anaerobic treatment of propylene glycol at concentrations higher than 1,500 mg COD m(-3) day(-1) was not convenient due to instable effluent COD ...
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69013-28-1 - Tall oil, polymer with dipropylene glycol, glycerol and phthalic anhydride - Searchable synonyms, formulas, resource links, and other chemical information.
QY Research Reports described a depth and professional market study and forecast trends on Global and China Dipropylene Glycol Monoethyl Ether (DPE) Industry Research Report 2013. This report also includes more info about basic overview of the industry including definitions, applications and industry china structure.. ...
Earlier this month, a leak developed in a Propylene Oxide refining column at LyondellBasell. Force Majeure has been declared by LyondellBasell on all Propylene Oxide derivatives as they have been forced to significantly cut production as a result. As Propylene Oxide is a precursor to Propylene Glycol, this plant issue has had immediate impact to Propylene Glycol.. LyondellBasell is one of just a handful of US Propylene Glycol manufacturers, and a large and key part of PG supply in the US. The situation could be several weeks before back-to-normal. In the meantime, Lyondells customers are on 70% allocation, and increases are taking effect.. For further questions about how this may effect your Propylene Glycol supply and/or price, reach out to your sales representative today.. ...
Catalog No. : P020007 Product Name : Heptaethylene Glycol Monomethyl Ether Synonyms : mPEG7-OH CAS# : 4437-01-8 M.F. : C15H32O8 M.W. : 340.41 Purity : |98% Packing Size : 1g,5g,25g,100g,1kg,100kg Appearance : Liquid LEO BIOCHEM specializes in the...
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Asthma inhalers. When propylene glycol is injected, it is metabolized in the human body into pyruvic acid (a normal part of the glucose-metabolism process, readily converted to energy), acetic acid (handled by ethanol-metabolism), lactic acid (a normal acid generally abundant during digestion) [9] , and propionaldehyde. Because of its low chronic oral toxicity, propylene glycol was classified by the U. S. Food and Drug Administration as generally recognized as safe (GRAS) for use as a direct food additive. Citation. Propylene Glycol Studies. The following is the abstract from a study done by the following doctors: O. H. ROBERTSON, CLAYTON G. LOOSLI, THEODORE T. PUCK, HENRY WISE, HENRY M. LEMON and WILLIAM LESTER, JR. It is entitled: TESTS FOR THE CHRONIC TOXICITY OF PROPYLEXE GLYCOL AND TRIETHYLENE GLYCOL ON MONKEYS AND RATS BY VAPOR INHALATION AND ORAL ADMINISTRATION. Citation. With a view to determining the safety of employing the vapors of propylene glycol and triethylene glycol in ...
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Recently, the Oil Products Company Oleon launched bio-based propylene glycol manufacturing factories in Belgium Ertvelde, a total of 120 people participated the activity, including employees of local government officials, the leadership of BASF and Oleon Ertvelde. As the worlds leading factory, the process of production applys a high degree of sustainable technologies.. Traditionally, propylene glycol is derived by the hydrolysis of epoxy propane, while the new factory produces the chemical by the decomposition of glycerol in the by-product of oil of oil. In addition, using glycerol to produce propylene glycol significantly reduces the production steps, thereby increases the efficiency of the production of bio-based propylene glycol.. BASF is not only studies this glyceryl production with the Oleon company, but also provides a vital catalyst for the production process.. Michael Baier, the BASF catalyst vice president, said: Its very honored to cooperate with Oleon, and introduce this new ...
Sadara Chemical Companys propylene glycol plant began production, marking another key step towards the completion of the companys petrochemicals complex. Sadara began production at its mixed-feed cracker in 2016. The complex includes 26 total plants in Jubail II Industrial City, with 22 now operational. Propylene glycol is used for cosmetics and fragrances, food and flavorings, and paints and coatings. Derivatives of the propylene glycol can also be used for making mono, di, and tri propylene glycol.. ...
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Purpose: Fingolimod recently became the first oral agent to reduce relapses and delay progression in multiple sclerosis. However, macular edema is one of its adverse effects. The aim of this study was to perform a literature review and identify factors associated with successful outcomes in the management of fingolimod associated macular edema (FAME).. Methods: We performed a systematic literature search of MEDLINE, Embase and Cochrane databases. We identified 13 reports describing 20 eyes with FAME. We performed multiple independent 2-tailed t-tests to compare visual outcomes between patients who ceased fingolimod treatment once FAME was diagnosed vs. those who continued with fingolimod. We also compared visual outcomes between treated vs. untreated eyes. Further, we compared the time to resolution with treatment vs. without.,br /,. Results: FAME resulted in a mean loss of 3.43 lines of vision (P = 0.04) and a range of 0-8 lines lost. Fingolimod was stopped in 35% of eyes diagnosed with FAME, ...
The electronic and geometric structures of poly [3-(4-octylphenyl)thiophene] have been studied by X-ray and ultraviolet photoelectron spectroscopy (XPS and UPS, respectively). Thermochromic effects, and new charge induced states generated by potassium doping, have been observed by direct UPS measurements. The experimental results are in very good agreement with the results of theoretical quantum chemical calculations performed with the Austin Model 1 semi-empirical model and the valence-effective Hamiltonian pseudo-potential model.. ...
High Health Hazard. Skin, eye and Lung irritant and possible organ system toxicity. Irritation can be seen at low inclusion rates of Propylene Glycol. Propylene glycol has many functions such as a solvent or solubalizing aid. It can be irritating to the skin with studies showing it can provoke allergic reactions in patients with eczema and other skin allergies. Extended exposure to Propylene Glycol has also been linked to the development of asthma and allergic reactions in children. Having a small molecular weight it can be absorbed through the skin. It has been shown to cause liver abnormalities and kidney damage in laboratory animals. REFERENCES:(1. References: (1. http://www.ewg.org/skindeep/ingredient/705315/PROPYLENE_GLYCOL/#. ). ...
Propylene glycol typically has a two-year shelf life. This number can vary slightly, depending on conditions of storage. Propylene glycol is used as an emulsifier in a variety of food, personal and liquid detergent products.Source:Lyondell Basell: Propylene GlycolMore Information:Dow Chemical: Propylene Glycol Safe Use
The Global and Chinese Di Propylene Glycol Di Acrylate Industry, 2012-2022 Market Research Report is a professional and in-depth study on the current state of the global Di Propylene Glycol Di Acrylate industry with a focus on the Chinese market. The report provides key statistics on the market status of the Di Propylene Glycol Di…
Felbamate (marketed under the brand name Felbatol by MedPointe) is an anticonvulsant used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy. Felbamate has been proposed to a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors, particularly isoforms containing the NR2B subunit. Although it is clear that felbamate does cause pharmacological inhibition of NMDA receptors, the relevance of NMDA receptor blockade as a strategy for the treatment of human epilepsy has been questioned. Therefore, the importance of the effects of felbamate on NMDA receptors to its therapeutic action in epilepsy is uncertain. August 1993. Felbamate was approved for partial seizures ...
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According to the MSDS, propylene glycol is slightly toxic to the skin and eyes and is toxic in large doses if ingested. Of some concern is that the compound is absorbed through the skin, meaning that large surface exposures result in symptoms similar to those produced through ingestion. In particular, propylene glycol causes damage to the central nervous system, which includes the brain and spinal cord. There is also animal evidence that it has mutagenic properties, meaning it can lead to cancer, and that it is a teratogen, meaning it causes birth defects. While large dose inhalation is rare due to the low volatility of propylene glycol, if heated and inhaled it can cause respiratory irritation and central nervous system disruption.. ...
Propylene glycol, also known as 1,2-propane-diol, is a multifunctional chemical used in several industrial fields, pharmaceuticals, food and cosmetics. Conventionally, it is obtained from petroleum based feedstock for industrial scale production. Recent developments have uncovered a new technique for obtaining propylene glycol from corn starch. The process involves production of carbohydrates from starch.. Biobased products are adopted on the premise that they are environment friendly attributed to their renewable origin. However, environment friendliness of any product depends upon various factors some of which include emission of green house gases throughout various steps involved in a products lifecycle, i.e., from raw material production to degradation of after-use residues through production, distribution and end-use. Some biobased products might be environment friendly until they are converted to finished products but might breakdown into toxic residual materials. Biobased propylene glycol ...
Nov 19, 2018· Propylene glycol (CH8O2) is a commonly used drug solubilizer in topical, oral, and injectable medications. It is used as stabilizer for vitamins, and as a water-miscible cosolvent. Propylene glycol has been used for over 50 years in a large variety of applications. As a pharmaceutical additive, propylene glycol is generally regarded as safe ...
US Pharm. 2013;38(12):36-37.. Method of Preparation: Calculate the quantity of each ingredient for the amount to be prepared. Accurately weigh or measure each ingredient. Using a magnetic stirrer, add about 80 mL of propylene glycol to an appropriate-sized beaker. Slowly sprinkle the hydroxypropyl cellulose 1,500 cps onto the stirred propylene glycol and mix well. Combine the benzocaine, lidocaine, and tetracaine powders to form a eutectic. Add to the gel mixture and mix thoroughly. Add sufficient propylene glycol to final volume and mix well. Allow mixture to set to remove any air bubbles. Package and label.. Use: This preparation has been used as a topical anesthetic prior to various procedures.. Packaging: Package in tight, light-resistant containers.. Labeling: Keep out of reach of children. Discard after ______ [time period].. Stability: A beyond-use date of 30 days may be used for this preparation.1. Quality Control: Quality-control assessment can include theoretical weight compared with ...
2016 Global Mono propylene glycol Report is a professional and in-depth research report on the worlds major regional market conditions of the Mono propylene glycol industry, focusing on the main regions (North America, Europe and Asia) and the main countries (United States, Germany, Japan and China).. Access full report with TOC @ http://www.fiormarkets.com/report/global-mono-propylene-glycol-market-research-report-2016-6067.html. The report firstly introduced the Mono propylene glycol basics: definitions, classifications, applications and industry chain overview; industry policies and plans; product specifications; manufacturing processes; cost structures and so on. Then it analyzed the worlds main region market conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. In the end, the report introduced new project SWOT analysis, investment feasibility analysis, and investment return analysis.. The report includes ...
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(KudoZ) English to Spanish translation of myreth-3 myristate/propylene glycol isoceteth-3 acetate/propylene glycol ceteth-: mirido-3 miristato/propileno glicol isocetido-3 acetato/propileno glicol cetido- [chemistry - Chemistry; Chem Sci/Eng].
A clear, odourless liquid. Propylene glycol is a humectant, and can be used between 1-8% in water based recipes such as lotion to draw moisture to the skin, similar to glycerin. It can also be used as a carrier for fragrance or essential oils. Another common use is in vaping products. This Propylene Glycol is Pharmaceutical grade meeting the specifications of the British and European Pharmacopoeia (BP/USP).. INCI: Propylene Glycol ...
PROPYLENE GLYCOL USP GRADE Propylene Glycol is a nearly odorless clear liquid with a mild sweet taste.Propylene Glycol is used in many industries. Pro
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Propylene glycol is a clear, colourless liquid that has no smell or taste. It is a chemical produced by adding propylene oxide with water. Glycol can be used as a stabilizer, to keep foods moist and can be found in many of the foods we eat on a daily basis. Industrial grade Propylene Glycol is used as one of many ingre
Propylene Glycol PG502 is a buffered, molybdate treated, industrial grade propylene glycol concentrate used to prevent corrosion of both ferrous and non-ferrous alloys.
Propylene Glycol And Thc Oil Work CBD Products: How To Mix Thc And Cbd Oil Cbd Oil For Pain Etsy Propylene Glycol And Thc Oil Faes Milano. such as grandpas birthday and meeting some relatives will be a little awkward For example, there are basically few children who have left the family before. Also, looked at any added ingredients and considered those with artificial preservatives and chemicals to be a bad option for people with arthritis. However, the demolition of a building, even if it is an abandoned building, requires the approval of many departments, and the approval process of each department takes about XX working days and they will have to rest when they catch up with May Day Therefore, this building could not be demolished for a while. CBD can help support and increase the longterm functionality of the Endocannabinoid System ECS, which helps regulate sleep, appetite, mood, immune function. Fortunately, this Propylene man is a master of physique, and his Glycol body And is strong, ...
110-49-6 Methylglycol acetate testing. Laboratory testing for CAS number 110-49-6. «beta»-Methoxyethyl acetate;Ethylene glycol acetate monomethyl ether;Ethylene glycol methyl ether acetate;Ethylene glycol monomethyl ether acetate;Glycol monomethyl ether acetate;Methyl cellosolve acetate;Methyl glycol acetate;2-Methoxyethanol acetate;2-Methoxyethyl acetate;CH3C(O)O(CH2)2OCH3;Acetate de Lether monomethylique de Lethylene-glycol;Acetate de methyle glycol;Acetato di metil cellosolve;Acetic acid 2-methoxyethyl ester;Ae.
As you may or may not know currently, Vaper Empire uses E-Liquid that contains Propylene Glycol (PG). This is the main ingredient absorbed into the lungs, as opposed to 4000 chemicals inhaled when smoking a conventional cigarette. A recently published research article explores the toxicology profiles on various types of glycols with varying molecular structures including Mono/Di/Tri/Propyl. The results are very interesting as according to the data not one of the glycols tested revealed any evidence of mutagenic, carcinogenic or developmental/reproductive toxicity potential to homo-sapiens (humans). Any pathology that was noted far exceeded the concentrations adopted for the research guidelines or alternatively were involved in mechanisms that are irrelevant to human physiology. In conclusion, the current safety evaluations of the USEPA, FDA, ATSDR, and NTP for these particular compounds adhere to the fundamental conclusion that propylene glycols present an extremely low risk to human health.
I searched out 12,000 article RLIBY database found on our Web Site, below, and only found one article. It did not deal with your problem. Then I searched Enviro$en$e at http://es.epa.org and got 120 hits. Let me know if you need help searching this site. Rudy Moehrbach Waste Reduction Resource Center Raleigh, NC, 29569 Web Site http:/www.p2pays.org/wrrc FAX 919-715-1612 Tel 919-715-6533 or 1-800-476-8686 , -----Original Message----- , From: Marlyn Aguilar - SHWB [SMTP:[email protected]] , Sent: Wednesday, June 03, 1998 11:03 AM , To: [email protected] , Subject: Propylene Glycol Coolant , , Hello, , , Does anyone know what can be done with Propylene Glycol Coolant , (product) that is used in chiller units and HVAC systems? It is less , hazardous than ethylene glycol, but its use is not as diverse. It , is not regulated, but will probably be shipped off as waste. Any , information would be helpful. , , Thanks , , Marlyn Aguilar , Hawaii Dept of Health , Solid and Hazardous ...
GIVE IT A REST ALREADY. First and foremost, FIREBALL WHISKY is NOT Whiskey. it is Cinnamon-Flavored WHISKY! Second, Propylene Glycol is not the same as the Ethylene Glycol used in most Auto Anti-Freeze. Propylene Glycol is used in Non-Toxic Marine Anti-Freeze and numerous FDA-Approved Foods & Drinks. All of the Fucktarded Freelance Wannabe Journalists out…
Mono propylene glycol (also known as propylene glycol, PG, propan1, 2diol and MPG) is a clear, colourless, and viscous liquid with a characteristic odour. It has the formula C 3 H 8 O, is soluble in water, and has hygroscopic properties. MPG is used across a wide range of industries as it has low toxicity, coupled with a freezing point which is ...
Propylene glycol is an alcohol that functions as a skin conditioner, viscosity-decreasing agent, solvent and fragrance ingredient in cosmetics. Propylene glycol has humectant properties. It dries on the skin to form a hygroscopic film that retains moisture by creating a barrier that prevents water from evaporating. Furthermore it is thought to function by an osmotic mechanism that attracts water to the outer skin layers, which accounts for the observation that it leads to a transient swelling of these skin layers. It also helped enhance the occlusive properties of specialised formulations, NLC, by reducing water loss across the surface of the skin, also known as transepithelial water loss, TEWL.. ...
... (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... a b Propylene glycol alginate, Food and Agriculture Organization of the United Nations ... What is the "propylene glycol alginate" found in salad dressings? at The Straight Dope ...
... artificial additives such as maltodextrin and propylene glycol; and common artificially separated and extracted ingredients ...
propylene glycol. *PEG-4 (polyethylene glycol). *sodium lauryl sulfate. *sodium metabisulfite. *BHT (butylated hydroxytoluene)- ...
QA16QA01 Propylene glycol. QA16QA02 Sodium propionate. QA16QA03 Glycerol. QA16QA04 Ammonium lactate. QA16QA05 Clanobutin. ...
It is soluble in propylene glycol, paraffin oil, and kerosene. It has a fruity odor, similar to pineapple. It occurs naturally ...
Propylene glycol should be replaced when it turns a reddish color. When an aqueous solution of propylene glycol in a cooling or ... Pre-inhibited propylene glycol solutions can also be used instead of pure propylene glycol to prevent corrosion. Besides ... Propylene glycol is considerably less toxic than ethylene glycol and may be labeled as "non-toxic antifreeze". It is used as ... Like ethylene glycol and propylene glycol, glycerol is a non-ionic kosmotrope that forms strong hydrogen bonds with water ...
... products sold in Canada do not contain propylene glycol. The MiO Energy variant of MiO is not sold in Canada. MiO ... All MiO products contain propylene glycol, except those sold in Canada. MiO is listed as containing less than 2% natural ... Other listed ingredients are citric acid, propylene glycol, malic acid, sucralose, acesulfame potassium, potassium citrate, ...
Propylene glycol alginate (PGA). E 405 agar. E 406 carrageen. E 407. red algae ...
Acetol can be converted to propylene glycol. This converts to formate and acetate (the latter converting to glucose), or ...
E-liquids are also sold without propylene glycol, without nicotine, or without flavors. The benefits and the health risks of e- ... However, they can also be filled with a mixture of propylene glycol, glycerin, and nicotine. (e.g. tobacco-free nicotine). ... E-liquids usually contain propylene glycol, glycerin, water, nicotine, and flavorings. The nicotine in liquids can range from 0 ...
The solvents used are polyethylene glycol 400 and propylene glycol. As a preservative, the injectable solution contains benzyl ... Lorazepam for injection formulated with polyethylene glycol 400 in propylene glycol with 2.0% benzyl alcohol as preservative. ... Toxicity from propylene glycol has been reported in the case of a patient receiving a continuous lorazepam infusion. ... Yaucher NE, Fish JT, Smith HW, Wells JA (2003). "Propylene glycol-associated renal toxicity from lorazepam infusion". ...
Schneider, Steven (2014). "Background Review for the excipent propylene glycol" (PDF). Europe Medicines Agency. Retrieved ... Finland and Sweden reported that Fireball contained amounts of propylene glycol that surpassed the EU limitations of 1g/kg. ...
They generally contain glycol (such as propylene glycol) or glycerin-based additives. For home-made acrylic retarder, water ... Non-toxic car anti-freeze, which contains propylene glycol can also be used. "Home Made Acrylic Retarders". Archived from the ...
Propylene glycol was once a common ingredient in soft moist cat food. According to the FDA "It was known for some time that ... In light of this new data, CVM amended the regulations to expressly prohibit the use of propylene glycol in cat foods." There ... However, recent reports in the veterinary literature of scientifically sound studies have shown that propylene glycol reduces ... propylene glycol caused Heinz Body formation in the red blood cells of cats (small clumps of proteins seen in the cells when ...
The dispersants used contain propylene glycol, 2-butoxyethanol, and dioctyl sodium sulfosuccinate. Earthjustice and Toxipedia ...
The two most common e-liquid bases are propylene glycol (PG) and vegetable glycerin (VG). Propylene glycol is tasteless and ... The liquid typically contains 95% propylene glycol and glycerin. Propylene glycol and glycerine are used to produce the vapor ... "Propylene Glycol vs. Vegetable Glycerin E-Liquid - What's the Difference?". Ecigarette Mag. Retrieved 10 January 2016. "About ... The aerosol is made-up of liquid sub-micron particles of condensed vapor, which mostly consist of propylene glycol, glycerol, ...
Propylene glycol and glycerin have not been shown to be safe. Some research states that propylene glycol emissions may cause ... The primary base ingredients of the liquid solution is propylene glycol and glycerin. About 20% to 27% of propylene glycol and ... there are e-liquids sold without propylene glycol, nicotine, or flavors. The liquid typically contains 95% propylene glycol and ... Being exposed to propylene glycol may cause irritation to the eyes and respiratory tract. The risk from the inhalation of ...
... mold fungus using various glycols, principally propylene glycol and triethylene glycol. In principle, these chemical substances ... "Reregistration eligibility decision for propylene glycol and dipropylene glycol". EPA 739-R-06-002. For a review of the ... For a review of the toxicity of propylene glycol, see: United States Environmental Protection Agency (September 2006). " ... "The bactericidal action of propylene glycol vapor on microorganisms suspended in air. i". Journal of Experimental Medicine. 75 ...
It contains propylene glycol, propylparaben, methylparaben, and diazolidinyl urea. It is a Registered Trademark of ...
The pink water is typically propylene glycol and water. (The −50 °F/−45 °C commercial product is 40:60.) Pink dye is used to ... Normal antifreeze (an ethylene glycol and water mixture) is colored green or blue to show that it is a toxic chemical. ...
For staining purposes Sudan IV can be made up in propylene glycol[1]. Alternatively, authors have reported using the dye ...
The risk is probably low from the inhalation of propylene glycol and glycerin. No information is available on the long-term ... E-liquid is the mixture used in vapor products such as e-cigarettes and generally consists of propylene glycol, glycerin, water ... The liquid in the e-cigarette, called e-liquid, is usually made of nicotine, propylene glycol, glycerine, and flavorings. Not ... While the ingredients vary the liquid typically contains 95% propylene glycol and glycerin. There are many e-liquids ...
Application of propylene glycol is another treatment method. Retinoids are used for some conditions. Exposure to sunlight may ...
The substance easily mixes with acetone, ethanol, and propylene glycol. Furthermore, chlorfenvinphos is corrosive to metal and ...
The reaction is carried out at 130-135 °C. Propylene glycol is removed through distillation under vacuum at above 120 °C. The ... The transesterification involves sucrose and fatty acid methyl ester in a solvent, propylene glycol. A basic catalyst, such as ...
... double-walled heat exchangers even though propylene glycol is non-toxic. Even though the HTF contains glycol to prevent ... The most common HTF is an antifreeze/water mix that typically uses non-toxic propylene glycol. After heating in the panels, the ... Pressurized antifreeze systems use a mix of antifreeze (almost always non-toxic propylene glycol) and water mix for HTF in ... Many indirect systems use antifreeze (e.g., propylene glycol) in the heat transfer fluid. In some direct systems, collectors ...
Methylcellulose, propylene glycol and glycerine are synthetic demulcents. Mandel, I. D. (1987). "The Functions of Saliva". ...
... annually produces 27000 metric tonnes of propylene oxide, 14,000 metric tonnes of propylene glycol and ... It markets propylene glycol and polyols It is based in Chennai. ...
Catalytic transformation of propylene carbonate into dimethyl carbonate and propylene glycol. ... Industrially, ethylene and propylene oxides readily react with carbon dioxide to give ethylene and propylene carbonates (with ... One example is propylene carbonate with melting point −55 °C and boiling point 240 °C. Other advantages are low ecotoxicity and ... For example, poly(propylene carbonate) and poly(bisphenol A carbonate) (Lexan). Dimethyl carbonate, a representative acyclic ...
Ethylene glycol Polylactic acid Propylene glycol "1,3-propanediol - Compound Summary". PubChem Compound. USA: National Center ...
The Global and Chinese Propylene Glycol monomethyl Ether propinate (PMP)... ... Check for Discount on 2016 Propylene Glycol monomethyl Ether propinate (PMP) Industry Market Report report by Prof Research. ... 8.3 Effects to Propylene Glycol monomethyl Ether propinate (PMP) Industry Chapter Nine Market Dynamics of Propylene Glycol ... 1.2 Development of Propylene Glycol monomethyl Ether propinate (PMP) Industry 1.3 Status of Propylene Glycol monomethyl Ether ...
HENAN PROSPER CHEMICALS propylene glycol monomethyl ether, reliable chemical products supplier in China. 15+ years history. ... Propylene glycol ethers and glycol ethers belong to the glycol ether solvents. The toxicity of propylene glycol ethers to the ... Glycol Ethers ACID ALCOHOL AMINES CHLORINATED SOLVENTS ACRYLATES Support Analysis of Propylene Glycol Analysis of Acetone ... Propylene glycol methyl ether has a weak ether smell, but it does not have a strong irritating odor, making its use more ...
Home / Coating Solvent and Industrial Cleaning / Propylene glycol monomethyl ether propionate(PMP). Propylene glycol monomethyl ... Be the first to review "Propylene glycol monomethyl ether propionate(PMP)" Cancel reply ... glycol acid resin, crylic acid resin, epoxy resin and nitrocellulose etc.. ... Propylene glycol mono methyl ether acetate (PMA). *Propylene glycol monomethyl ether propionate(PMP) ...
Propylene glycol alginate, Food and Agriculture Organization of the United Nations What is the "propylene glycol alginate" ... Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... esterified with propylene glycol, some are neutralized with an appropriate alkali, and some remain free. List of food additives ...
... β-propylene glycol). Propylene glycol is a clear, colorless and hygroscopic liquid. Propylene glycol contains an asymmetrical ... Ethylene Glycol and Propylene Glycol Toxicity U.S. Department of Health and Human Services (public domain) Propylene Glycol - ... Final products contain 20% propylene glycol, 1.5% of dipropylene glycol and small amounts of other polypropylene glycols. ... propylene glycol reacts with propylene oxide to give oligomers and polymers that are used to produce polyurethanes. Propylene ...
Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... a b Propylene glycol alginate, Food and Agriculture Organization of the United Nations ... What is the "propylene glycol alginate" found in salad dressings? at The Straight Dope ...
Free propylene glycol. Determine the percentage of free propylene glycol in the sample by extracting 2 g of sample for 2 hours ... Propylene glycol alginate is an ester of alginic acid in which some of the carboxyl groups are esterified with propylene glycol ... of free propylene glycol using titration with 0.029 M periodic acid as described under the procedure for Total propylene glycol ... Propylene glycol alginate. Prepared at the 49th JECFA (1997). superseding specifications prepared at the 44th JECFA (1995),. ...
Propylene glycol is generally regarded as safe for use in food. Ethylene glycol has been found in at least 34, and propylene ... 57-55-6 Propylene Glycol, ATSDR, Agency for Toxic Substances and Disease Registry, DT, Division of Toxicology, ToxFAQs, ToxFAQs ... Exposure to large amounts of ethylene glycol can damage the kidneys, heart, and nervous system. ... glycol in at least 5, of the 1,416 National Priorities List sites identified by the Environmental Protection Agency (EPA). >, ...
PROPYLENE GLYCOL DIACETATE. ICSC. : 0943. 1,2-Diacetoxypropane. 1,2-Propylene diacetate. alpha Propylene glycol diacetate. ...
Toxicological profile for Propylene Glycol. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service. ...
The true propylene glycol content (in g/100 g of esters) is equal to the apparent propylene glycol content (in g/100 g of ... Each ml of 0.1N iodine is equivalent to 3.805 mg of propylene glycol. g propylene glycol/100 g of esters = If the qualitative ... Propylene glycol esters of fatty acids are mixtures of propylene glycol mono- and diesters of saturated and unsaturated fatty ... When pure reference material of other components such as propylene glycol and di-fatty acid esters of propylene glycol are ...
Large amounts of it are needed for this effect, unlike its more toxic cousin, ethylene glycol. Propylene glycol is not ... The vapor pressure of the propylene glycol is such that it keeps the relative humidity inside the humidor near 70%, which is ... A 1:1 mixture of propylene glycol and water (preferably distilled) is commonly used as the activator solution in cigar ... Propylene glycol increases the amound of acid in the body, resulting in metabolic problems. ...
... R-(-)-1,2-propanediol 1,2-Propanediol Propylene glycol PubChem Notes: Propylene Glycol A clear, colorless, viscous organic solvent and diluent used in pharmaceutical ... MediLexicon propylene glycol - Medical Dictionary Definition for Term propylene glycol [1. a solvent for several water- ... Propylene glycol - definition from Biology-Online.org [(Science: chemical) A clear, colourless, viscous liquid used as a ...
... MSDS Number: P6928 --- Effective Date: 12/08/96. 1. Product Identification. Synonyms: 1,2-propanediol; 1,2- ... Propylene Glycol (57-55-6) Yes Yes No Yes --------\Federal, State & International Regulations - Part 1\---------------- -SARA ... Propylene Glycol (57-55-6) No No No No --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- - ... Propylene Glycol (57-55-6) No No None 12. Ecological Information. Environmental Fate: When released into the soil, this ...
DL-Propylene glycol; propylene glycol (1,2-propanediol); 1,2-propanediol (propylene glycol); propanediol; Methyl glycol ... Other names: 1,2-Propanediol; «alpha»-Propylene glycol; Methylethyl glycol; Methylethylene glycol; Monopropylene glycol; PG 12 ... Propylene glycol USP; 1,2-Propylenglykol; Solar winter ban; Sentry Propylene Glycol; Isopropylene glycol; Ucar 35; Solargard P ... Sirlene; 1,2-Dihydroxypropane; 1,2-Propylene glycol; 2-Hydroxypropanol; 2,3-Propanediol; Propane-1,2-diol; Dowfrost; ...
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
2-Propylene glycol dinitrate Colorless liquid with a disagreeable odor. [Note: A solid below 18°F.] ... Ammonia compounds, amines, oxidizers, reducing agents, combustible materials [Note: Similar to Ethylene glycol dinitrate in ...
This document deals with the propylene glycol ethers most commonly used in industry, namely methoxypropanol, methoxypropyl ... NEG and NIOSH Basis for an Occupational Health Standard: Propylene Glycol Ethers and Their Acetatespdf icon [PDF - 3,309 KB] ... This document deals with the propylene glycol ethers most commonly used in industry, namely methoxypropanol, methoxypropyl ... NEG and NIOSH Basis for an Occupational Health Standard: Propylene Glycol Ethers and Their Acetates. ...
See Also: Toxicological Abbreviations Propylene glycol (ICSC) PROPYLENE GLYCOL (JECFA Evaluation) Propylene glycol (SIDS) ... Propylene glycol 1.2 Group Alcohol 1.3 Synonyms 1.2-propylene glycol; Alpha-beta-dioxypropan; alpha-propylene glycol; dowfrost ... An estimation of the serum propylene glycol concentration may be calculated from the osmolar gap. 1 g of propylene glycol has ... The following day the serum propylene glycol was 771 mg/dL. No source of serum propylene glycol other than silver sufadiazine ...
Propylene Glycol Coolant , , Hello, , , Does anyone know what can be done with Propylene Glycol Coolant , (product) that is ... used in chiller units and HVAC systems? It is less , hazardous than ethylene glycol, but its use is not as diverse. It , is not ... RE: Propylene Glycol Coolant. *Subject: RE: Propylene Glycol Coolant. *From: Rudy Moehrbach ,[email protected], ...
... from Dow is a pharmaceutical grade of Monopropylene Glycols (PG or MPG) with a specified purity greater than 99.8%. ... DOW PuraGuard™ Propylene Glycol (PG) USP/EP is a pharmaceutical grade of Monopropylene Glycols (PG or MPG) with a specified ... DOW PuraGuard™ Propylene Glycol USP/EP is available from Dow in various quantities. Please contact us for details on ... DOW PuraGuard™ Propylene Glycol USP/EP Application Overview: Cosmetics and Personal Care Industry (1.0MB PDF). ...
Products containing PROPYLENE GLYCOL made by company: CVS Corporation Showing 51 - 60 of 136 results See more: 1 2 3 4 5 6 7 8 ...
Skin Care , Sun , Sunscreen: Makeup containing PROPYLENE GLYCOL Showing 1 - 10 of 153 results See more: 1 2 3 4 5 6 7 8 9 ... ...
There is provided a process for producing propylene glycol monoacetate which comprises the steps of (I) hydroformylating vinyl ... When it is desired to finally provide propylene glycol by hydrolizing propylene glycol monoacetate, the propylene glycol ... While propylene glycol monoacetate is a compound useful as a starting material for the production of propylene glycol and ... Methods for preparing ester of 1,3-propylene glycol and 1,3- propylene glycol. ...
Learn about Propylene Glycol USP for animal usage including: active ingredients, directions for use, precautions, and storage ... Propylene Glycol USP. This page contains information on Propylene Glycol USP for veterinary use.. The information provided ... If animal is already showing symptoms of ketosis, mix one part water with one part propylene glycol and administer orally as a ... Propylene Glycol USP. This treatment applies to the following species:. *Dairy Cattle ...
Learn about Propylene Glycol (Canada) for animal usage including: active ingredients, directions for use, precautions, and ... Propylene glycol USP 100% v/v.. Propylene Glycol Indications. Partnar Propylene Glycol is indicated as an aid in the treatment ... Propylene Glycol (Canada). This page contains information on Propylene Glycol for veterinary use.. The information provided ... Every effort has been made to ensure the accuracy of the Propylene Glycol information published above. However, it remains the ...
Propylene glycol , C3H8O2 , CID 1030 - structure, chemical names, physical and chemical properties, classification, patents, ...
This specification covers a propylene-glycol base, deicing/anti-icing fluid in the form of a concentrated liquid. ... Deicing/Anti-Icing Fluid, Aircraft, Propylene- Glycol Base(NONCURRENT Jan 1995) AMS1427A. ...
Propylene glycol] is used in the Fireball flavor in very small quantities, less than 1/8th of the amount allowed by the U.S. ... No Fireball Whisky Recall Over Propylene Glycol In US, Company Says. By Connor Adams Sheets On 10/29/14 AT 11:35 AM ... version contains higher levels of propylene glycol, an ingredient that European countries limit more stringently than the U.S. ...
... glycerin and propylene glycol solution/ drops), including warnings and precautions, directions, and the names of other drugs ... Get an overview of ARTIFICAL TEARS (glycerin and propylene glycol solution/ drops), including its generic name, formulation (i. ...
... by 2024 - published on openPR.com ... Propylene Glycol Market : Industry Analysis & Overview Propylene glycol is a chemical that is produced by reaction of propylene ... Global Propylene Oxide Market: Taxonomy - By Application Polyether Polyols Propylene Glycols Propylene Glycol Ethers Others ... Food Grade Propylene Glycol Dioleate. Pharmaceutical Grade Propylene Glycol Dioleate. Market Segment by Applications, can be ...
Propylene Glycol (antifreeze) by Noah Brizendine , This newsletter was created with Smore, an online tool for creating ... Uses of Propylene Glycol some uses for antifreeze are mostly around the same topic. 3 uses of this chemical is that it is used ... Some other interesting facts about Propylene Glycol is that it is uses in massage therapy. They are used as a moisturizer in ... 3 Physical Properties of Propylene Glycol some of the many physical properties are quiet interesting actually. for one, it ...
  • More] Polyester-ether polyols were prepared by a clean method, consisting of PET wastes glycolysis with common diols (diethylene glycol and a mixture diethylene gycol/dipropylene glycol) and a diol derived from biomass (isosorbide) followed by mono-esterification of the glycolyzed products with phthalic anhydride and subsequent propolglation, under relatively mild conditions. (epa.gov)
  • Further purification produces finished industrial grade or USP/JP/EP/BP grade propylene glycol that is typically 99.5% or greater. (wikipedia.org)
  • This page contains information on Dow industrial grade propylene glycol. (brenntag.com)
  • Industrial-grade propylene glycol is a colorless liquid with a distinctive odor. (brenntag.com)
  • For more information on potential applications for industrial grade propylene glycol, contact Brenntag North America. (brenntag.com)
  • SAFE-T-THERM GRAS Biobased - NSF approved as HT1, it uses a renewable source USP grade propylene glycol and FDA approved corrosion inhibitors. (acculube.com)
  • SAFE-T-THERM Classic Biobased - Product uses renewable source industrial grade propylene glycol, is ideal for components in residential and commercial systems. (acculube.com)
  • SAFE-T-THERM HD Biobased - Ideal for high demand applications, it uses renewable source industrial grade propylene glycol, has an enhanced corrosion package. (acculube.com)
  • For customers purchasing their products in bulk quantity, the good news is that the starting prices of the USP/BP/Food grade Propylene glycol are from very low with Xingang as delivery port and the minimum amount to order the USP/BP/Food grade Propylene glycol are 11911000020100000. (steunmijnclub.nl)
  • Food Grade Propylene Glycol Monostearate , bakery Baking Emulsifiers E477 Description: VIVIDR Propylene Glycol Monostearate is made from stearic acid and propylene glycol . (benadorassociates.com)
  • Propylene glycol is a clear liquid used in antifreeze and deicing solutions. (cdc.gov)
  • however, the closely related ethylene glycol (a key ingredient in antifreeze) is toxic to humans and to many animals. (wikipedia.org)
  • Ethylene glycol is used to make chemical properties that are similar to ethylene antifreeze and de-icing solutions for cars, airplanes, glycol, but it does not cause the same human health and boats. (cdc.gov)
  • Propylene glycol and propylene glycol are primarily glycol is used by the chemical, food, and responsible for the releases of both compounds into pharmaceutical industries as an antifreeze when the air, water, and soil. (cdc.gov)
  • AMSOIL Propylene Glycol Antifreeze & Coolant (ANT) is formulated to provide benefits beyond those provided by today's conventional antifreeze and coolant products. (amsoil.com)
  • Unlike conventional ethylene glycol-based products, which are acutely toxic, AMSOIL Propylene Glycol Antifreeze & Coolant is biodegradable and its low toxicity limits the threat to children and animals. (amsoil.com)
  • There are websites and spam e-mails stating that propylene glycol is really industrial antifreeze and that it's the major ingredient in brake and hydraulic fluids. (paulaschoice.com)
  • Since it is considered less toxic than ethylene glycol, it has been substituted for it in some antifreeze, and the incidence of toxic ingestion is expected to rise. (oncologynurseadvisor.com)
  • Likewise, in a patient with history of antifreeze ingestion with negative serum ethylene glycol or symptoms not typical of ethylene glycol intoxication, PG intoxication should be considered. (oncologynurseadvisor.com)
  • PG is widely available and has many legitimate uses, such as antifreeze and windshield washers, and there can be confusion regarding whether methanol, ethylene glycol, or PG is present in the product. (oncologynurseadvisor.com)
  • Do not be alarmed by the term antifreeze or by the chemical, propylene glycol. (naturallycurly.com)
  • The most common antifreeze fluid - ethylene glycol - must not be used where there is a chance of leakage to potable water or food processing systems. (engineeringtoolbox.com)
  • This precipitated a public outcry in Europe, where people recalled with horror the 1985 episode when some Austrian wines were adulterated with diethylene glycol, another chemical that can be used in antifreeze, to make the wines sweeter and more full-bodied in the style of late harvest wines . (montrealgazette.com)
  • Propylene glycol is significantly less toxic than ethylene glycol and may be labeled as "non-toxic antifreeze. (ecolink.com)
  • It is used as antifreeze where ethylene glycol would be inappropriate, such as in food-processing systems or in water pipes in homes where incidental ingestion may be possible. (ecolink.com)
  • Propylene glycol (IUPAC name: propane-1,2-diol) is a synthetic organic compound with the chemical formula C3H8O2. (wikipedia.org)
  • Propylene glycol , also called 1,2-propanediol or propane-1,2-diol , is an organic compound (a diol or double alcohol) with formula C 3 H 8 O 2 or HO-CH 2 -CHOH-CH 3 . (primidi.com)
  • Propylene glycol , known also by the systematic name propane-1,2-diol, is an organic compound (a diol alcohol ), usually a faintly sweet, and colorless clear viscous liquid that is hygroscopic and miscible with water , acetone , and chloroform . (thefullwiki.org)
  • The freezing point of water is depressed when mixed with propylene glycol owing to the effects of dissolution of a solute in a solvent (freezing-point depression). (wikipedia.org)
  • Propylene glycol is used as a humectant (E1520), solvent, and preservative in food and for tobacco products. (wikipedia.org)
  • Propylene Glycol A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. (scitoys.com)
  • Rapid intravenous injection of preparations of drugs containing propylene glycol as a solvent (in significant amounts) may cause unconsciousness, arrhythmias and even cardiac arrest. (inchem.org)
  • This may lead to misdiagnosis of the severe condition of ethylene glycol poisoning in a patient who has been given drugs containing, as a solvent, the relatively innocuous propylene glycol. (inchem.org)
  • 2.4 First-aid measures and management principles Considerable toxicity is unlikely after an acute exposure, with the exception of rare but dramatic arrhythmias including cardiac arrest after rapid i.v. injection of drugs containing large amounts of propylene glycol solvent. (inchem.org)
  • There is provided a process for producing propylene glycol monoacetate which comprises the steps of (I) hydroformylating vinyl acetate with a gaseous mixture of hydrogen and carbon monoxide in an organic solvent in the presence of a substantially water-insoluble rhodium complex and a tri-substituted. (google.com)
  • Propylene glycol is actually a better solvent than glycerin. (uspharmacist.com)
  • Notably, diazepam , which is insoluble in water, uses propylene glycol as its solvent in its clinical , injectable form. (thefullwiki.org)
  • The pharmaceutical industry uses propylene glycol as a solvent in formulations of drugs that are insoluble in water. (montrealgazette.com)
  • Propylene glycol is also used as a solvent in acrylics, stains, inks and dyes, and in cellophane and brake fluid. (awakeningspirit.com)
  • Propylene glycol is an odorless and colorless liquid, usually used as a solvent and wetting substance, making it a popular ingredient in shampoo, conditioner, toothpaste and cosmetics. (steunmijnclub.nl)
  • Eastman EastaPure™ PM acetate stabilized (propylene glycol monomethyl ether acetate) is a slow evaporating solvent with both ether and ester functional groups. (eastman.com)
  • Pure optical isomers can be obtained by hydration of optically pure propylene oxide. (wikipedia.org)
  • Industrially, propylene glycol is produced from propylene oxide (for food-grade use), and global capacity in 1990 was 900,000 tonnes per year. (wikipedia.org)
  • Related to this application, propylene glycol reacts with propylene oxide to give oligomers and polymers that are used to produce polyurethanes. (wikipedia.org)
  • 3. PHYSICO-CHEMICAL PROPERTIES 3.1 Origin of the substance Synthetic, manufactured by various ways, but recently by hydration of propylene oxide (Faith, Keyes & Clark's Industrial Chemicals, 1975). (inchem.org)
  • Propylene glycol is a chemical that is produced by reaction of propylene oxide with water. (openpr.com)
  • Industrially propylene glycol is produced by propylene oxide hydration. (thefullwiki.org)
  • Propylene glycol alginate is chemical combination of alginic acid and propylene oxide. (sbwire.com)
  • PG is a synthetic product obtained from the hydration of propylene oxide, which is derived from petroleum products. (naturallycurly.com)
  • Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for b. (sigmaaldrich.com)
  • In the traditional production process propylene glycol is made from propylene oxide reacted with water. (steunmijnclub.nl)
  • Mono propylene glycol is produced from propylene oxide. (steunmijnclub.nl)
  • The most common process is by the non-catalytic hydrolysis of propylene oxide in a high-temperature and high-pressure environment. (steunmijnclub.nl)
  • This document deals with the propylene glycol ethers most commonly used in industry, namely methoxypropanol, methoxypropyl acetate and dipropylene glycol monomethyl ether. (cdc.gov)
  • In order to meet environment regulations or standards the industry is now focusing on developing bio-based propylene glycol. (openpr.com)
  • Propylene glycol (also known as 1,2 propanediol) is a relatively small molecule with two alcohol (hydroxyl) groups (-OH). (naturallycurly.com)
  • Also known as 1,2-propanediol, propylene glycol has a chemical formula of C3H8O2 and a molecular weight of 76.10 g/mol. (brenntag.com)
  • However, large amounts of propylene glycol are needed to cause this effect. (cdc.gov)
  • Propylene glycol increases the amount of acid in the body, but large amounts of propylene glycol are needed in order to cause an unsafe amount of acid. (ecolink.com)
  • Propylene glycol alginate ( PGA ) is an emulsifier , stabilizer , and thickener used in food products. (wikipedia.org)
  • Chemically, propylene glycol alginate is an ester of alginic acid , which is derived from kelp . (wikipedia.org)
  • What is the "propylene glycol alginate" found in salad dressings? (wikipedia.org)
  • Propylene glycol alginate is an ester of alginic acid in which some of the carboxyl groups are esterified with propylene glycol, some neutralized with an appropriate alkali and some remain free. (fao.org)
  • List of food additives, Codex Alimentarius Propylene glycol alginate, Food and Agriculture Organization of the United Nations What is the "propylene glycol alginate" found in salad dressings? (wikipedia.org)
  • Propylene glycol alginate offers widespread application, hence offers multitude advantages to the manufacturers. (sbwire.com)
  • Propylene glycol alginate is extensively used in brewery industry as it stabilises the foam in the beer and hence prevents foam breakdown due to presence of any residual product. (sbwire.com)
  • Propylene glycol alginate is comprehensively used in food & beverage industry due to its distinctive properties such as thickening and emulsifying agent. (sbwire.com)
  • Therefore, it's wide spread applications accounts to escalating growth of propylene glycol alginate market. (sbwire.com)
  • Thus this may hamper the growth of propylene glycol alginate market. (sbwire.com)
  • Hence, these factors may inhibit the growth of propylene glycol alginate market. (sbwire.com)
  • Thus, propylene glycol alginate market is yet at exploratory stage of development. (sbwire.com)
  • Principally, propylene glycol alginate is derivative of alginic acid ester, which is obtained from kelp plant. (sbwire.com)
  • Propylene glycol alginate has widespread application such as thickening agent used in ice creams, salad dressing, and foam stabiliser especially used in brewery industries and widely used as food preservatives. (sbwire.com)
  • Propylene glycol alginate is also used as an ingredient in chewing gums and few condiments. (sbwire.com)
  • The global propylene glycol alginate market is categorised into seven regions, namely, Western Europe, Eastern Europe Middle East and Africa (MEA), Asia Pacific excluding Japan (APEJ), , Japan Latin America and, North America. (sbwire.com)
  • North America accounts for the highest consumption of propylene glycol alginate. (sbwire.com)
  • Europe also comprehends major share of propylene glycol alginate consumption. (sbwire.com)
  • Asia pacific region is expected to witness substantial growth for propylene glycol alginate market due to increased awareness on its application across various industries. (sbwire.com)
  • Propylene glycol is also used as a humectant, preservative in tobacco and food products, solvents and as a major constituent of e-liquid that is used in electric cigarettes with vegetable glycerin. (openpr.com)
  • Propylene glycol serves as Humectant - a substance that helps retain moisture content, or simply - it prevents things from drying out. (awakeningspirit.com)
  • Conclusions will be drawn about the significance of the small difference of heat transfer coefficient and boiling point between propylene glycol coolant and ethylene glycol coolant in the context of engine operation. (sae.org)
  • Moreover, it is replacing ethylene glycol, which was traditionally used as an anti-freeze and coolant in these industries, due to its toxic nature. (reportlinker.com)
  • Propylene glycol serves as coolant in many mobile applications nowadays and therefore a distribution grid already exists. (aiche.org)
  • The U.S. version contains higher levels of propylene glycol, an ingredient that European countries limit more stringently than the U.S. Food and Drug Administration -- which allows 50 grams of the ingredient per kilogram -- does. (ibtimes.com)
  • It seems the American version of the product found its way across the ocean with levels of propylene glycol above those acceptable in Europe. (montrealgazette.com)
  • The Cosmetic Ingredient Review Board and other groups have analyzed all of the toxicology data and exposure studies concerning topical application of propylene glycol as commonly used in cosmetics products. (paulaschoice.com)
  • The use of the "/" in the name indicates that the ingredient is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate. (cosmeticsinfo.org)
  • An ingredient found in many personal-care products like shampoo, hair conditioner, and styling product, propylene glycol is widely used because of its relatively low cost and versatile nature. (naturallycurly.com)
  • Back in the 1940's, Dr. Oswald Hope Robertson suspected that vaporized propylene glycol (a main ingredient in ecigs) could potentially kill the flu virus. (electroniccigarettesreviews.net)
  • Propylene Glycol USP/EP is used as an excipient (inactive ingredient) for the manufacturing of pharmaceutical products. (steunmijnclub.nl)
  • Final products contain 20% propylene glycol, 1.5% of dipropylene glycol and small amounts of other polypropylene glycols. (wikipedia.org)
  • Final products contain 20% 1,2-propanediol , 1.5% of dipropylene glycol and small amount of other polypropylene glycol. (thefullwiki.org)
  • This report focuses on the Propylene Glycol Dioleate (CAS 105-62-4) in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. (openpr.com)
  • The key segments for propylene glycol market are North America, Asia Pacific, Europe and Rest of the World (RoW). (openpr.com)
  • The major consumers of polypropylene glycol include the pharmaceutical and food and beverage industry, which account for major share in the market. (openpr.com)
  • Manufacturer of private label polypropylene glycol chemicals. (steunmijnclub.nl)
  • The growth in demand for engine coolants made from propylene glycol has created interest in engineering information on their performance. (sae.org)
  • Propylene glycol is a sticky, colorless liquid that is almost odorless but has a faintly sweet taste. (ecolink.com)
  • S-Propanediol may be synthesized from D-mannitol, through the following scheme: Forty-five percent of propylene glycol produced is used as chemical feedstock for the production of unsaturated polyester resins. (wikipedia.org)
  • Dipropylene glycol is used in unsaturated polyester resins and personal care products and tripropylene glycol has application in acrylates and polyurethanes. (openpr.com)
  • The industrial applications of propylene glycol are to manufacture paints and coatings, resins and plastics, used as an intermediate to manufacture other chemical substances such as unsaturated polyester resins that are used in pipes or windmill blades and bath and kitchenware. (openpr.com)
  • Hence growing demand for unsaturated polyester resins to boost demand for propylene glycol in the near future. (openpr.com)
  • Propylene glycol is in the production of unsaturated polyester resins that, in turn, go into items that effect our daily lives, like water tanks, or our leisure time, like sailing boats. (steunmijnclub.nl)
  • Get an overview of ARTIFICAL TEARS (glycerin and propylene glycol solution/ drops), including its generic name, formulation (i.e. pill, oral solution, injection, inhaled medicine) and why it's used. (healthgrades.com)
  • Hydroxypropyl cellulose is soluble 1 in 2 parts water, 1 in 2.5 parts ethanol, and 1 in 5 parts propylene glycol, but it is practically insoluble in glycerin and oils. (uspharmacist.com)
  • Propylene glycol (C 3 H 8 O 2 ) occurs as a clear, colorless, viscous, practically odorless liquid with a sweet taste, somewhat resembling glycerin. (uspharmacist.com)
  • The major companies such as Cargill, ADM and The Dow Chemical company are manufacturing propylene glycol from glycerin. (openpr.com)
  • What is Glycerin-propylene glycol? (patientslikeme.com)
  • Glycerin-propylene glycol is a combination lubricant for the eye used for dry eyes and to keep them lubricated all day. (patientslikeme.com)
  • There are no evaluations for Glycerin-propylene glycol. (patientslikeme.com)
  • Read user comments about the side effects, benefits, and effectiveness of Artificial Tears glycerin-propylene glycol. (webmd.com)
  • The e-liquid in electronic cigarettes is made from a blend of propylene glycol, vegetable glycerin, nicotine, and flavorings. (electroniccigarettesreviews.net)
  • Propylene glycol is generally considered to be a safe chemical, and is not routinely tested for, unless specific exposure, such as to a medicine or cosmetic, can be linked with symptoms. (cdc.gov)
  • Pure propylene glycol can be obtained from chemical suppliers for much more reasonable prices. (everything2.com)
  • PROPYLENE GLYCOL International Programme on Chemical Safety Poisons Information Monograph 443 Chemical 1. (inchem.org)
  • information about ethylene glycol and to emphasize the human health effects that may result from If you are exposed to a hazardous chemical such as exposure to it. (cdc.gov)
  • Propylene glycol is a chemical that has physical and absorbs water. (cdc.gov)
  • The key players for propylene glycol market include: Arch Chemicals, Lyondell Chemical Co, SKC Chemicals Group, The Dow Chemical Company, BASF AG, Huntsman, Repsol YPF and more. (openpr.com)
  • The reference is to propylene glycol, a chemical added to some dog foods to help retain moisture. (montrealgazette.com)
  • Home 1 / News 2 / Chemical Safety 3 / Is Propylene Glycol Safe? (ecolink.com)
  • Sadara Chemical Company's propylene glycol plant began production, marking another key step towards the completion of the company's petrochemicals complex. (us-sabc.org)
  • Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers. (unboundmedicine.com)
  • We evaluated the chemical and enzymatic stabilities of prodrugs containing methoxy, ethoxy and propylene glycol linkers in order to find a suitable linker for prodrugs of carboxylic acids with amino acids. (unboundmedicine.com)
  • This work suggests that the propylene glycol linker is an optimal linker for amino acid prodrugs since it has good chemical stability and is enzymatically hydrolyzed to yield the parent drug. (unboundmedicine.com)
  • TY - JOUR T1 - Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers. (unboundmedicine.com)
  • TNJ Chemical Industry Co.,Ltd. is a professional Buy Propylene glycol USP grade at factory price from China suppliers suppliers and we will offer best quality Buy Propylene Glycol for sale. (steunmijnclub.nl)
  • It may exist in air in the vapor form, although propylene glycol must be heated or briskly shaken to produce a vapor. (cdc.gov)
  • The vapor pressure of the propylene glycol is such that it keeps the relative humidity inside the humidor near 70%, which is generally recognized to be ideal for cigar storage and aging. (everything2.com)
  • Propylene glycol is also used in machines that simulate smoke, and in the electronic cigarettes, propylene glycol functions to provide the vapor mist that looks like smoke and is used to suspend flavor. (electricnicotine.com)
  • Propylene glycol is also used to create artificial smoke or fog used in fire-fighting training and theatrical productions, as well as e-cigarettes, because it produces a smoke-like vapor when heated and mixes well with flavoring ingredients. (ecolink.com)
  • You can be exposed to propylene glycol by eating food products, using cosmetics, or taking medicine that contains it. (cdc.gov)
  • The Food and Drug Administration has classified propylene glycol as "generally recognized as safe," which means that it is acceptable for use in flavorings, drugs, and cosmetics, and as a direct food additive. (cdc.gov)
  • Propylene glycol has been approved by the FDA as an additive that is "generally recognized as safe " for use in food , used to absorb extra water and maintain moisture in certain medicine s, cosmetics , or food products. (everything2.com)
  • In fact, research from toxicologists has shown that propylene glycol and similar ingredients don't present a health risk for people when used in cosmetics. (paulaschoice.com)
  • In cosmetics, propylene glycol is used in small amounts to keep products from melting in high heat or from freezing. (paulaschoice.com)
  • One of the key growth factors for global propylene glycol supply market is the increasing demand of the propylene glycol as an anti-freeze agent in industries such as automotive, personal care, and cosmetics due to its non-toxic nature. (reportlinker.com)
  • In cosmetics and personal care products, Propylene Glycol monoesters and diesters are used in the formulation of moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks. (cosmeticsinfo.org)
  • All the propylene glycol monoesters and diesters may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union . (cosmeticsinfo.org)
  • Propylene glycol is used in the coloring of food, flavoring foods, and as an additive to keep things moist, including medicines and cosmetics. (electricnicotine.com)
  • The Food and Drug Administration has classified propylene glycol as an additive that is "generally recognized as safe," which means that it is acceptable to use in flavorings, drugs, and cosmetics, and as a direct food additive. (ecolink.com)
  • Propylene glycol is used for cosmetics and fragrances, food and flavorings, and paints and coatings. (us-sabc.org)
  • Propylene GlycolPropylene glycol USP/EP (pharmaceutical grade) is the only grade of propylene glycol used in health-sensitive applications, such as foodstuffs, animal feed, cosmetics and pharmaceuticals. (steunmijnclub.nl)
  • Dipropylene Glycol (DPG) from MPL is designed for odor-sensitive applications such as fragrances and cosmetics. (steunmijnclub.nl)
  • Propylene glycol is not likely to exist in large amounts in air. (cdc.gov)
  • Large amounts of it are needed for this effect, unlike its more toxic cousin , ethylene glycol . (everything2.com)
  • Propylene glycol is non-toxic when ingested, even in reasonably large amounts. (naturallycurly.com)
  • In an interesting study, some rats were fed propylene glycol at amounts equal to 5% of all of their food intake every day for two years, which is a pretty huge volume over a large portion of their lifetime. (naturallycurly.com)
  • The practical processing of larger amounts of polyalcohols such as propylene glycol to synthesis gas for fuel cell applications in reactors larger than laboratory scale suited for distributed applications has not been adequately addressed to date. (aiche.org)
  • Propylene glycol is used in small amounts to keep products from melting or freezing and helps active ingredients penetrate the skin. (ecolink.com)
  • Global Info Research offers a latest published report on Propylene Glycol Dioleate Market Analysis and Forecast 2019-2025 delivering key insights and providing a competitive advantage to clients through a detailed report. (openpr.com)
  • Propylene Glycol Industry Global Market Research report presents an in-depth analysis of the Propylene Glycol market size, growth, share, segments, manufacturers, and forecast, competition landscape and growth opportunity. (marketwatch.com)
  • Propylene glycol is miscible with water, chloroform, and acetone and is hygroscopic in nature. (openpr.com)
  • Japan is also expected to contribute major share in propylene glycol market due to rapidly changing consumer consumption pattern towards food preferences. (sbwire.com)
  • Propylene glycol (PG) can be used as a food additive and is widely accepted as safe for human consumption at low levels. (chromatographyonline.com)
  • Propylene glycol has a very high demand due to the significantly high petroleum consumption globally. (steunmijnclub.nl)
  • Product Name Propylene Glycol (Tech Grade) CAS No 57-55-6 Molecular Formula C3H8O2 Molecular Weight 76.09 Introduction Propylene Glycol is a water-white sticky-thick hydrophilic liquid, with the stable character. (benadorassociates.com)
  • Although the properties of propylene glycol coolants and ethylene glycol coolants are similar, testing was required to determine the effects of this change for current designs at the limits of the expected range of operating conditions. (sae.org)
  • The performance of propylene glycol coolants at high ambient temperatures and under high load conditions was compared to ethylene glycol coolants both on the engine dynamometer and in vehicles operated on specific sections of highway in the high desert areas of California, Nevada and Arizona and a desert proving ground. (sae.org)
  • The results will be reported, comparing the heat transfer performance of propylene glycol engine coolants to ethylene glycol coolants in high temperature service. (sae.org)
  • Also, the growing automotive industry in Asia-Pacific is driving the market as propylene glycol is widely used in engine coolants and sheet molding compounds among others. (sbwire.com)
  • Propylene glycol is used for many industrial and consumer applications such as feed, food and beverages, pharmaceutical and cosmetic among others. (openpr.com)
  • However, propylene glycol is generally regarded as safe when used as a pharmaceutical additive. (ecolink.com)
  • Propylene Glycol USP, referring to the United States and European Pharmacopeia, is a high-purity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications. (steunmijnclub.nl)
  • However, we do contact), the other chemicals to which you are not know how many of the 1,416 NPL sites have exposed, and your individual characteristics such as been evaluated for ethylene glycol. (cdc.gov)
  • Data were found suggesting that Propylene Glycol Dicaprylate/Dicaprate and Propylene Glycol Dipelargonate may enhance the skin penetration of other chemicals. (cosmeticsinfo.org)
  • While few chemicals are entirely without risk, propylene glycol is considered to be safe at the low concentrations, used in personal care products and even food products. (naturallycurly.com)
  • This simple formula is free of propylene glycol, chlorhexidine, parabens and other harsh chemicals, contains no artificial colors, and is fragrance-free. (amazon.com)
  • The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is "generally recognized as safe" for use in food. (cdc.gov)
  • a) The additive is the reaction product of succinic anhydride, fully hydrogenated vegetable oil (predominantly C 16 or C 18 fatty acid chain length), and propylene glycol. (cornell.edu)
  • As a food additive, propylene glycol is metabolized in the body and used as a normal carbohydrate source. (ecolink.com)
  • The WHO (World Health Organization) have set the maximum permissible daily intake of propylene glycol as a food additive at 25 mg/kg bodyweight. (chromatographyonline.com)
  • Propylene Glycol in Food: Is This Additive Safe? (steunmijnclub.nl)