A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.
A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)
A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.
A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.
Substances that provide protection against the harmful effects of freezing temperatures.
Uptake of substances through the SKIN.
Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.
4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.
The presence of free HEMOGLOBIN in the URINE, indicating hemolysis of ERYTHROCYTES within the vascular system. After saturating the hemoglobin-binding proteins (HAPTOGLOBINS), free hemoglobin begins to appear in the urine.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
The application of suitable drug dosage forms to the skin for either local or systemic effects.
Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as EPOXY RESINS.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.
Propylene or propene polymers. Thermoplastics that can be extruded into fibers, films or solid forms. They are used as a copolymer in plastics, especially polyethylene. The fibers are used for fabrics, filters and surgical sutures.
The chemical and physical integrity of a pharmaceutical product.
Unsaturated hydrocarbons of the type Cn-H2n, indicated by the suffix -ene. (Grant & Hackh's Chemical Dictionary, 5th ed, p408)
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794)
Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)

Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway. (1/714)

FTY720 is a novel immunosuppressive drug derived from a metabolite from Isaria sinclairii that is known to induce apoptosis of rat splenic T cells. In this study, we examined the intracellular signaling pathway triggered by FTY720. Treatment of human Jurkat T lymphocytes with FTY720-induced apoptosis characterized by DNA fragmentation. The same treatment induced activation of protein kinases such as c-Jun NH2-terminal kinase (JNK), p38/CSBP (CSAID-binding protein), and a novel 36-kDa myelin basic protein (MBP) kinase, but not extracellular signal-regulated kinase (ERK). Pretreatment of Jurkat cells with DEVD-CHO blocked FTY720-induced DNA fragmentation as well as the activation of p38/CSBP. However, DEVD-CHO treatment failed to inhibit FTY720-induced activation of JNK and the 36-kDa MBP kinase. We have also demonstrated that activation of the ERK signaling pathway completely suppressed the FTY720-induced apoptotic process including activation of caspase 3 and activation of JNK and the 36-kDa MBP kinase. Furthermore, transient expression of constitutively active mitogen-activated protein kinase/ERK kinase (MEK) protected the cells from FTY720-induced cell death. The effect of MEK was canceled by coexpression of a mitogen-activated protein kinase phosphatase, CL100. These results indicate that JNK and p38 pathways are differentially regulated during FTY720-induced apoptosis and that activation of ERK pathway alone is sufficient to cancel the FTY720-induced death signal.  (+info)

Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action. (2/714)

Felbamate is an anticonvulsant used in the treatment of seizures associated with Lennox-Gastaut syndrome and complex partial seizures that are refractory to other medications. Its unique clinical profile is thought to be due to an interaction with N-methyl-D-aspartate (NMDA) receptors, resulting in decreased excitatory amino acid neurotransmission. To further characterize the interaction between felbamate and NMDA receptors, recombinant receptors expressed in Xenopus oocytes were used to investigate the subtype specificity and mechanism of action. Felbamate reduced NMDA- and glycine-induced currents most effectively at NMDA receptors composed of NR1 and NR2B subunits (IC50 = 0.93 mM), followed by NR1-2C (2.02 mM) and NR1-2A (8.56 mM) receptors. The NR1-2B-selective interaction was noncompetitive with respect to the coagonists NMDA and glycine and was not dependent on voltage. Felbamate enhanced the affinity of the NR1-2B receptor for the agonist NMDA by 3.5-fold, suggesting a similarity in mechanism to other noncompetitive antagonists such as ifenprodil. However, a point mutation at position 201 (E201R) of the epsilon2 (mouse NR2B) subunit that affects receptor sensitivity to ifenprodil, haloperidol, and protons reduced the affinity of NR1-epsilon2 receptors for felbamate by only 2-fold. Furthermore, pH had no effect on the affinity of NR1-2B receptors for felbamate. We suggest that felbamate interacts with a unique site on the NR2B subunit (or one formed by NR1 plus NR2B) that interacts allosterically with the NMDA/glutamate binding site. These results suggest that the unique clinical profile of felbamate is due in part to an interaction with the NR1-2B subtype of NMDA receptor.  (+info)

A Saprolegnia parasitica challenge system for rainbow trout: assessment of Pyceze as an anti-fungal agent for both fish and ova. (3/714)

A reproducible Saprolegnia parasitica spore delivery system was developed and demonstrated to be effective in providing a sustained spore challenge for up to 10 d. Treatment of rainbow trout with slow-release intraperitoneal implants containing cortisol resulted in chronically elevated blood cortisol levels and rendered the fish susceptible to infection by S. parasitica when exposed to the spore challenge. Sham-implanted fish were not susceptible to infection. Bronopol (2-bromo-2-nitro-propane-1,3-diol), formulated as Pyceze, was effective in protecting predisposed fish from infection by S. parasitica when administered as a daily bath/flush treatment at concentrations of 15 mg l-1 and greater. Pyceze was also demonstrated to protect fertilised rainbow trout ova from S. parasitica challenge when administered as a daily bath/flush treatment at concentrations of between 30 and 100 mg l-1. Pyceze appears to qualify as a safe and effective replacement for malachite green and formalin in the prevention of fungal infections in the aquaculture environment.  (+info)

Development and testing of a microbiological assay to detect residual effects of disinfectant on hard surfaces. (4/714)

We describe a glucuronidase bioassay for detecting residual bactericidal activity from the use of disinfectants on hard surfaces; in this assay we used formaldehyde, ethanol, isopropanol, chlorine, and a commercial preparation containing 2-bromo-2-nitro-1, 3-propanediol. Chlorine and the commercial preparation showed bactericidal activity (53.5% and 98.2%, respectively) for a week after disinfection.  (+info)

Assessment of adult and neonatal reproductive parameters in Sprague-Dawley rats exposed to propylene glycol monomethyl ether vapors for two generations. (5/714)

This study evaluated propylene glycol monomethyl ether (PGME) in a rat 2-generation reproduction study, which included non-traditional study end points, such as sperm count and motility, developmental landmarks, estrous cyclicity, and weanling organ weights. Groups of 30 male and 30 female Sprague-Dawley rats (6-weeks-old) were exposed to 0, 300, 1000, or 3000 ppm of PGME vapors via inhalation for 6 hours/day, 5 days/week prior to mating, and 6 hours/day, 7 days/week during mating, gestation, and lactation, for 2 generations. These concentrations corresponded to estimated oral equivalent doses of 0, 396, 1325, or 3974 mg/kg/day. At 3000 ppm, toxicity in the P1 and P2 adults was marked, as evidenced by sedation during and after exposure, and mean body weights which were as much as 21% lower than controls. This marked parental toxicity was accompanied by lengthened estrous cycles, decreased fertility, decreased ovary weights, and histologic ovarian atrophy in maternal rats. In the offspring from these dams, decreased body weights, reduced survival and litter size, slight delays in puberty onset, and histologic changes in liver and thymus in the F1 and F2 offspring were observed. The nature of the reproductive/neonatal effects and their close individual animal correlation with decreased maternal body weights suggested that these effects were secondary to general toxicity and/or nutritional stress. No such reproductive/neonatal effects were observed at 1000 ppm, a concentration which caused less marked, but significant body weight effects without sedation. There were no treatment-related effects of any kind noted at 300 ppm of PGME. Therefore, the no-observable-effect level (NOEL) for reproductive/neonatal effects was 1000 ppm, and that for parental toxicity was 300 ppm.  (+info)

FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation. (6/714)

Background-Effective immunosuppression is a critical determinant of organ and patient survival in cardiac transplantation. The present study was designed to determine the potency of FTY720, a new synthesized immunosuppressant, and examine its clinical potential as an immunosuppressant. Methods and Results-Hearts of DBA/2 mice were transplanted heterotopically in C57BL/6 mice. Recipients were treated with oral FTY720 in doses of 0.3, 1, 3, or 10 mg. kg(-1). d(-1) or with 40 mg. kg(-1). d(-1) of cyclosporin A (CsA) as a comparative treatment. The median graft survival time (MST) was significantly prolonged by treatment with FTY720 10 mg. kg(-1). d(-1). MST was not prolonged by FTY720 1 mg. kg(-1). d(-1) or CsA. However, FTY720 1 mg. kg(-1). d(-1) combined with CsA 40 mg. kg(-1). d(-1) resulted in a significant prolongation of MST. Histopathological studies performed 5 days after transplantation demonstrated remarkable suppression of inflammatory response by treatment with FTY720 10 mg. kg(-1). d(-1). Interleukin (IL)-2 and interferon (IFN)-gamma production was not suppressed; however, cytotoxic T lymphocyte activity was strongly suppressed in vitro. In addition, IL-2-stimulated T-cell proliferation and class I and class II MHC antigen expression on IFN-gamma-stimulated macrophages were strongly inhibited by FTY720. Histopathological studies 60 days after transplantation (DBA/2-B10.D2) demonstrated a beneficial effect on graft atherosclerosis. Conclusions-FTY720 promoted long-term cardiac graft survival and strongly inhibited the progression of graft atherosclerosis. These observations suggest that FTY720 has a promising clinical potential in cardiac transplantation.  (+info)

Short-chain alcohols promote an early stage of membrane hemifusion. (7/714)

Hemifusion, the linkage of contacting lipid monolayers of two membranes before the opening of a fusion pore, is hypothesized to proceed through the formation of a stalk intermediate, a local and strongly bent connection between membranes. When the monolayers' propensity to bend does not support the stalk (e.g., as it is when lysophosphatidylcholine is added), hemifusion is inhibited. In contrast, short-chain alcohols, reported to affect monolayer bending in a manner similar to that of lysophosphatidylcholine, were here found to promote hemifusion between fluorescently labeled liposomes and planar lipid bilayers. Single hemifusion events were detected by fluorescence microscopy. Methanol or ethanol (1.2-1.6 w/w %) added to the same compartment of the planar bilayer chamber as liposomes caused a 5-50 times increase in the number of hemifusion events. Alcohol-induced hemifusion was inhibited by lysophosphatidylcholine. Promotion of membrane hemifusion by short-chain alcohol was also observed for cell-cell fusion mediated by influenza virus hemagglutinin (HA). Alcohol promoted a fusion stage subsequent to the low pH-dependent activation of HA. We propose that binding of short-chain alcohol to the surface of membranes promotes hemifusion by facilitating the transient breakage of the continuity of each of the contacting monolayers, which is required for their subsequent merger in the stalk intermediate.  (+info)

A phase I and pharmacological study of protracted infusions of crisnatol mesylate in patients with solid malignancies. (8/714)

This Phase I and pharmacological study was performed to assess the feasibility of administering the polycyclic aromatic hydrocarbon crisnatol in increasingly prolonged continuous i.v. infusions to patients with advanced solid malignancies. The study also sought to characterize the-principal toxicities of crisnatol on this schedule, to recommend doses for subsequent disease-directed studies, and to characterize possible associations between pharmacological parameters and toxicity. Sixteen patients were treated with 40 courses of crisnatol administered as a continuous i.v. infusion. The initial dose-schedule was 750 mg/m2/day for 6 days, and the duration of the infusion was to be progressively increased by 3-day increments to 9, 12, 15, 18, and 21. Courses were to be repeated every 4 weeks. Moderate to severe central nervous system (CNS) toxicity precluded the administration of crisnatol 750 mg/m2/day for longer than 6 days, and, therefore, the dose of crisnatol was reduced to 600 mg/m2/day. At this dose, three of five patients receiving a 12-day infusion experienced dose-limiting toxicity, which consisted of pulmonary thromboembolism (two patients) and grade 4 thrombocytopenia (one patient). None of the six patients completing a 9-day infusion at 600 mg/m2/day developed dose-limiting toxicity during the first or second course of crisnatol. At this dose level, the plasma concentrations at steady state (Css) averaged 1607.8+/-261.1 ng/ml, which exceeds minimal inhibitory concentrations for most tumors in vitro (1000 ng/ml). In fact, the administration of crisnatol at a dose of 600 mg/m2/day for 9 days resulted in the longest duration that biologically relevant plasma crisnatol concentrations have been sustained. Plasma Css values were significantly higher in patients who experienced severe CNS toxicity compared with those who did not (2465.3+/-1213.5 versus 1342+/-447.3 ng/ml; P = 0.04). There were no relationships evident between the clearance of crisnatol and indices reflecting renal and hepatic functions. One patient with a glioblastoma multiforme experienced a partial response lasting 14 months. The relative lack of intolerable CNS toxicity at the recommended dose for Phase II studies of crisnatol, 600 mg/m2/day for 9 days, as well as the magnitude of the Css values achieved and the antitumor activity observed at this dose, are encouraging. However, the mechanisms for the apparently increased thrombogenicity observed in this trial are unclear and require further elucidation.  (+info)

Hemoglobinuria can be caused by a variety of factors, including:

1. Blood disorders such as sickle cell disease, thalassemia, and von Willebrand disease.
2. Inherited genetic disorders such as hemophilia.
3. Autoimmune disorders such as autoimmune hemolytic anemia.
4. Infections such as septicemia or meningococcemia.
5. Toxins such as lead, which can damage red blood cells and cause hemoglobinuria.
6. Certain medications such as antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs).
7. Kidney disease or failure.
8. Transfusion-related acute lung injury (TRALI), which can occur after blood transfusions.
9. Hemolytic uremic syndrome (HUS), a condition that occurs when red blood cells are damaged and broken down, leading to kidney failure.

The symptoms of hemoglobinuria may include:

1. Red or brown-colored urine
2. Frequent urination
3. Pale or yellowish skin
4. Fatigue
5. Shortness of breath
6. Nausea and vomiting
7. Headache
8. Dizziness or lightheadedness
9. Confusion or loss of consciousness in severe cases.

Diagnosis of hemoglobinuria is typically made through urine testing, such as a urinalysis, which can detect the presence of hemoglobin in the urine. Additional tests may be ordered to determine the underlying cause of hemoglobinuria, such as blood tests, imaging studies, or biopsies.

Treatment of hemoglobinuria depends on the underlying cause and severity of the condition. In some cases, treatment may involve addressing the underlying condition that is causing the hemoglobinuria, such as managing an infection or stopping certain medications. Other treatments may include:

1. Fluid and electrolyte replacement to prevent dehydration and maintain proper fluid balance.
2. Medications to help remove excess iron from the body.
3. Blood transfusions to increase the number of red blood cells in the body and improve oxygen delivery.
4. Dialysis to filter waste products from the blood when the kidneys are unable to do so.
5. Supportive care, such as oxygen therapy and pain management.

In severe cases of hemoglobinuria, complications can include:

1. Kidney damage or failure
2. Septicemia (blood infection)
3. Respiratory failure
4. Heart problems
5. Increased risk of infections and other complications.

Prevention of hemoglobinuria involves managing any underlying medical conditions, such as diabetes or infections, and avoiding certain medications that can cause the condition. It is also important to seek medical attention if symptoms of hemoglobinuria develop, as early treatment can help prevent complications and improve outcomes.

Example sentence: "The patient was diagnosed with lactic acidosis secondary to uncontrolled diabetes and was admitted to the intensive care unit for proper management."

1. Adverse drug reactions (ADRs): These are side effects caused by medications, such as allergic reactions, liver damage, or other systemic problems. ADRs can be a significant cause of iatrogenic disease and can result from taking the wrong medication, taking too much medication, or taking medication for too long.
2. Infections acquired during medical procedures: Patients who undergo invasive medical procedures, such as surgeries or insertion of catheters, are at risk of developing infections. These infections can be caused by bacteria, viruses, or other microorganisms that enter the body through the surgical site or the catheter.
3. Surgical complications: Complications from surgery can range from minor issues, such as bruising and swelling, to more serious problems, such as infection, organ damage, or nerve injury. These complications can be caused by errors during the procedure, poor post-operative care, or other factors.
4. Medication overuse or underuse: Medications that are prescribed inappropriately or in excess can cause iatrogenic disease. For example, taking too much medication can lead to adverse drug reactions, while taking too little medication may not effectively treat the underlying condition.
5. Medical imaging complications: Medical imaging procedures, such as X-rays and CT scans, can sometimes cause iatrogenic disease. For example, excessive radiation exposure from these procedures can increase the risk of cancer.
6. Psychiatric iatrogenesis: This refers to harm caused by psychiatric treatment, such as medication side effects or inappropriate use of electroconvulsive therapy (ECT).
7. Overdiagnosis: Overdiagnosis occurs when a condition is diagnosed that would not have caused symptoms or required treatment during the person's lifetime. This can lead to unnecessary testing, treatment, and other iatrogenic harms.
8. Unnecessary surgery: Surgical procedures that are not necessary can cause harm and increase healthcare costs.
9. Inappropriate referrals: Referring patients for unnecessary tests or procedures can lead to iatrogenic disease and increased healthcare costs.
10. Healthcare provider burnout: Burnout among healthcare providers can lead to errors, adverse events, and other forms of iatrogenic disease.

It is important to note that these are just a few examples of iatrogenic disease, and there may be other factors that contribute to this phenomenon as well. Additionally, while many of the factors listed above are unintentional, some may be due to negligence or other forms of misconduct. In all cases, it is important for healthcare providers to take steps to prevent iatrogenic disease and promote high-quality, patient-centered care.

Codex Alimentarius Propylene glycol alginate, Food and Agriculture Organization of the United Nations What is the "propylene ... Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... esterified with propylene glycol, some are neutralized with an appropriate alkali, and some remain free. List of food additives ...
... is also present in propylene glycol alginate, which is known as E405. Propylene glycol is a compound which is ... α-propylene glycol to distinguish it from the isomer propane-1,3-diol, known as (beta) β-propylene glycol. Propylene glycol is ... However, the study authors write that glycol ethers and not propylene glycol are the likely culprit. Propylene glycol has not ... Ethylene Glycol and Propylene Glycol Toxicity U.S. Department of Health and Human Services (public domain) Propylene Glycol - ...
... (PGDN, ttup 1,2-propylene glycol dinitrate, or 1,2-propanediol dinitrate) is an organic chemical, an ... C3H6(ONO2)2 → 3 CO + 3 H2O + N2 The principal current use of propylene glycol dinitrate is as a propellant in Otto Fuel II, ... "Propylene glycol dinitrate". NIOSH Pocket Guide to Chemical Hazards. Centers for Disease Control and Prevnetion. (Articles ... Nitrates of polyhydric alcohols, of which propylene glycol dinitrate is an example, have been used in medicine for the ...
... (PGME or 1-methoxy-2-propanol) is an organic solvent with a wide variety of industrial and ... Di(propylene glycol) methyl ether Record in the GESTIS Substance Database of the Institute for Occupational Safety and Health " ... Propylene glycol methyl ether; 1-Methoxy-2-propanol" (PDF). Msdssearch.dow.com. Retrieved 2015-05-22. Bosen, Sidney F.; Bowles ... Similar to other glycol ethers, it is used as a carrier/solvent in printing/writing inks and paints/coatings. It also finds use ...
PEG-120 Propylene Glycol Stearate, PEG-10 Propylene Glycol, PEG-8 Propylene Glycol Cocoate, and PEG-55 Propylene Glycol Oleate ... Polyethylene glycol propylene glycol cocoates or PEG propylene glycol cocoates are chemical compounds produced by the ... "Final Report on the Safety Assessment of PEG-25 Propylene Glycol Stearate, PEG-75 Propylene Glycol Stearate, ... Their chemical designation is PEG-8, referring to its polyethylene glycol (PEG) molecular chain length. PEG propylene glycol ...
... (PGMEA, 1-methoxy-2-propanol acetate) is a P-type glycol ether used in inks, coatings, ... "PROPYLENE GLYCOL METHYL ETHER ACETATE - CAMEO Chemicals - NOAA". http://www.dow.com/scripts/litorder.asp?filepath=oxysolvents/ ... Retrieved 2014-08-01.{{cite web}}: CS1 maint: archived copy as title (link) "Shell Glycol Ethers and Acetates". "Eastman ...
It finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers. The commercial product is ... Di(propylene glycol) methyl ether is an organic solvent with a variety of industrial and commercial uses. ... "Dipropylene Glycol Methyl Ether" (PDF). inchem.org. v t e (Chemical articles with multiple compound IDs, Multiple chemicals in ...
... propylene glycol) diglycidyl ether and poly(ethylene glycol) monooleate". The Journal of Chemical Thermodynamics. 130: 38-46. ... Poly(propylene glycol) diglycidyl ether (PPGDGE) is an organic chemical in the glycidyl ether family. There are a number of ... "Poly(propylene glycol) diglycidyl ether". Sigma Aldrich. Jagtap, Ameya Rajendra; More, Aarti (2022-08-01). "Developments in ... "Dow Epoxy Resins" (PDF). "Poly(propylene glycol) (600) diglycidyl ether". www.polysciences.com. Retrieved 2022-05-17. " ...
Jacob, Sharon E; Scheman, Andrew; McGowan, Maria A (2018). "Propylene Glycol". Dermatitis. 29 (1): 3-5. doi:10.1097/DER. ... Propylene Glycol 2017 - Alkyl Glucoside 2016 - Cobalt 2015 - Formaldehyde 2014 - Benzophenones 2013 - Methylisothiazolinone - ...
Other major products are polypropylene glycol, propylene glycol ethers, and propylene carbonate. The United States Food and ... About 20% of propylene oxide is hydrolyzed into propylene glycol, via a process which is accelerated by acid or base catalysis ... 3-propylene oxide, better known as oxetane. Industrial production of propylene oxide starts from propylene. Two general ... With water, propylene glycol is produced. With alcohols, reactions, called hydroxylpropylation, analogous to ethoxylation occur ...
... are used to prepare low-molecular-weight polyethylene glycol. Ethylene Propylene glycol Monoethylene glycol Diethylene glycol ... Polyethylene glycol is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers ... Not to be confused with propylene glycol.) PEG is the main ingredient in the paint (known as "fill") in paintballs. PEG is ... Polyethylene glycol, Chemindustry.ru Wikimedia Commons has media related to Poly(ethylene glycol). Wikimedia Commons has media ...
... artificial additives such as maltodextrin and propylene glycol; and common artificially separated and extracted ingredients ...
See the article on propylene glycol for more information. The relative sweetness of ethylene glycol and propylene glycol is ... Pure propylene glycol does not taste bitter, and pure propylene glycol is often used as a food additive, for instance in cake ... There is a difference in the mixing ratio, depending on whether it is ethylene glycol or propylene glycol. For ethylene glycol ... Ethylene Glycol and Propylene Glycol Toxicity CDC - NIOSH Pocket Guide to Chemical Hazards Antifreeze ratio for Ethylene Glycol ...
The pink water is typically propylene glycol and water. (The −50 °F/−45 °C commercial product is 40:60.) Pink dye is used to ... Normal antifreeze (an ethylene glycol and water mixture) is colored green or blue to show that it is a toxic chemical. ...
... propylene glycol alginate (PGA, food additive with E number E405), pectins and gellan gum have also been investigated as foam ... "Mechanism of beer foam stabilization by propylene glycol alginate". Journal of the Institute of Brewing. 86 (1): 34-37. doi: ...
It is soluble in propylene glycol, paraffin oil, and kerosene. It has a fruity odor, similar to pineapple, and is a key ...
Since melarsoprol is insoluble in water, dosage occurs via a 3.6% propylene glycol intravenous injection. To avoid the risk of ... Melarsoprol should be given using glass syringes (if they can be reliably sterilized). The propylene glycol it contains is ...
Acetol can be converted to propylene glycol. This converts to pyruvate (by two alternative enzymes), or propionaldehyde, or to ...
101 Deicing fluids are based on ethylene glycol or propylene glycol.: 4 Airports use pavement deicers on paved surfaces ... Microbial populations decomposing propylene glycol consume large quantities of dissolved oxygen (DO) in the water column.: 2-23 ... ethylene and propylene glycol exert high levels of biochemical oxygen demand, consuming oxygen needed by aquatic life. ... including runways and taxiways, which may contain potassium acetate, glycol compounds, sodium acetate, urea or other chemicals ...
"CDC - NIOSH Pocket Guide to Chemical Hazards - Propylene glycol monomethyl ether". www.cdc.gov. Retrieved 11 April 2018. Nice, ... typically containing glycol ethers or diethylene glycol, to transfer pressure from the controlling mechanism to the braking ... The system is usually filled with a glycol-ether based brake fluid (other fluids may also be used). At one time, passenger ... "CDC - NIOSH Pocket Guide to Chemical Hazards - Ethylene glycol". www.cdc.gov. Retrieved 11 April 2018. " ...
E-liquids are also sold without propylene glycol, nicotine, or flavors. The benefits and the health risks of e-cigarettes are ... Various additives are combined into the shredded tobacco product mixtures, with humectants such as propylene glycol or glycerol ... E-liquids usually contain propylene glycol, glycerin, nicotine, flavorings, additives, and differing amounts of contaminants. ... which have been found to contain propylene glycol, glycerin, nicotine, flavors, small amounts of toxicants, carcinogens, and ...
Sometimes the oil is also mixed with propylene glycol and polyethylene glycol to make it less viscous. Vaporizing is more ... E-liquids are also sold without propylene glycol, nicotine, or flavors. The benefits and the health risks of e-cigarettes are ... E-liquids usually contain propylene glycol, glycerin, nicotine, flavorings, additives, and differing amounts of contaminants. ... they can also be filled with a combination propylene glycol, glycerin, and drugs such as nicotine (e.g. extract from tobacco) ...
Application of propylene glycol is another treatment method. Retinoids are used for some conditions. Exposure to sunlight may ...
The solvents used are polyethylene glycol 400 and propylene glycol. As a preservative, the injectable solution contains benzyl ... Lorazepam for injection formulated with polyethylene glycol 400 in propylene glycol with 2.0% benzyl alcohol as preservative. ... Toxicity from propylene glycol has been reported in the case of a person receiving a continuous lorazepam infusion. Intravenous ... High-dose or prolonged parenterally administered lorazepam with its associated solvent can cause propylene glycol intoxication ...
As of 2018, Fireball does not use propylene glycol in any of their products. There are a variety of cinnamon-flavored liquor ... Schneider, Steven (2014). "Background Review for the excipent propylene glycol" (PDF). Europe Medicines Agency. Retrieved ... Finland and Sweden reported that Fireball contained amounts of propylene glycol that surpassed the EU limitations of 1g/kg. ...
... and prevention of propylene glycol toxicity". Seminars in Dialysis. Wiley. 20 (3): 217-9. doi:10.1111/j.1525-139x.2007.00280.x ...
Synthetic demulcents include methylcellulose, propylene glycol, and glycerin. "Definition of DEMULCENT". www.merriam-webster. ...
Lester W, Dunklin E, Robertson OH (1952). "Bactericidal effects of propylene and triethylene glycol vapors on airborne ... Triethylene glycol is placed into contact with natural gas, and strips the water out of the gas. Triethylene glycol is heated ... Glycols are also used as liquid desiccants for natural gas and in air conditioning systems. It is an additive for hydraulic ... Triethylene glycol is a member of a homologous series of dihydroxy alcohols. It is a colorless, odorless and stable liquid with ...
For staining purposes, Sudan IV can be made up in propylene glycol. Alternatively, authors have reported using the dye ...
They generally contain glycol (such as propylene glycol) or glycerin-based additives. For home-made acrylic retarder, water ... In painting, a retarder is a substance, usually a glycol and usually added to water, that is used to slow the drying time of ...
... antioxidant Propylene glycol - humectant Propylene glycol alginate - thickener, vegetable gum, stabilizer, emulsifier Propylene ... Lactylated fatty acid esters of glycerol and propylene glycol - emulsifier Larch gum - Lard - Latolrubine - color Laurel berry ... Prune kernel oil - marketed as a gourmet cooking oil Poly vinyl pyrrolidone - Polydextrose - humectant Polyethylene glycol 8000 ... glycol esters of fatty acids - emulsifier Propylparaben (propyl para-hydroxybenzoate) - preservative Pumpkin seed oil - a ...
... such as propylene glycol or a combination of propylene glycol and ethylene glycol. Most air-cooled engines use some liquid oil ... However, coolant based on propylene glycol is liquid to −55 °C, colder than is encountered by many engines; shrinks slightly ...
... preparation containing benzyl alcohol derivative, polysorbate 80 and propylene glycol should be used in ...
Ethylene oxide, a gas, was used for synthesis of ethylene glycol. Ethylene glycol, a liquid, was used to manufacture ... Propylene oxide is used in polyurethane foams and in rigid polymers. The side products of the reaction include styrene and tert ... "Propylene Oxidation Looms as Route to Oxide". Chemical and Engineering News. 43 (43): 40-42. October 25, 1965. doi:10.1021/cen- ... In the late 1970s Halcon and Arco planned to build two new plants at Channelview, Texas, one for propylene oxide processing, ...
... it markets propylene glycol and polyols Manali Petrochemical annually produces 27000 metric tonnes of propylene oxide, 14,000 ... metric tonnes of propylene glycol and 15,000 metric tonnes of polyether polyol and system polyol. Manali Petrochemical Ltd ...
... ethylene glycol or propylene glycol, vinegar, etc. Since the dry rot fungus requires an acidic environment from pH 0 to 5.5, ... Glycol solutions have an advantage in that they can be applied over paint.[citation needed] Glycol and boron solutions are ... Boron/glycol preservatives consist of an inorganic boron preservative dissolved in a glycol to produce a paste. These are water ... The use of boron/glycol preservatives do show improved penetration. Another criticism of the orthodox approach is the sheer ...
It is very slightly soluble in water, and soluble in ethanol and propylene glycol. It is insoluble in paraffin oil. It is ...
Ethylene glycol and propylene glycol exert high levels of biochemical oxygen demand (BOD) during degradation in surface waters ... Deicing fluids are typically based on propylene glycol or ethylene glycol, which freeze at a lower temperature than water. ... in the water column are consumed when microbial populations decompose propylene glycol.: 2-23 Sufficient dissolved oxygen ... Typically fan-jet engines cannot be deiced with glycol based fluids, as doing so could cause damage to the engine itself or to ...
Its ingredients may include various compounds: water lactic acid gluconic acid lauramine oxide propylene glycol n-butyl ether ... glycolic acid sulfamic acid disodium capryloamphodipropionate ethylene glycol n-butyl ether citric acid One formulation is (by ...
An emulsifier such as propylene glycol is used to suspend OC in water, and the suspension is then pressurized to make an ...
... having a rapid onset of action and not causing metabolic acidosis from the propylene glycol vehicle (which is not required due ...
Castor oil derivatized with propylene oxide makes polyurethane foam for mattresses and yet another new derivative is used in ... The example below shows the reaction of triolein with ozone and ethylene glycol. Air oxidation, (autoxidation), the chemistry ...
... drug-induced Photoallergic Photoirritant Plant derivative-induced Pollen-induced Polyester resin dermatitis Propylene glycol- ...
... propylene glycol, flavorings, and other ingredients. The device has an electric heat source that heats the e-liquid to create ...
The reaction is carried out at 130-135 °C. Propylene glycol is removed through distillation under vacuum at above 120 °C. The ... The transesterification involves sucrose and fatty acid methyl ester in a solvent, propylene glycol. A basic catalyst, such as ...
... propylene glycol, and urea. These chemical denaturing agents lower the melting temperature (Tm) by competing for hydrogen bond ... DMSO Formamide Guanidine Sodium salicylate Propylene glycol Urea Thermal denaturation Beads mill Probe sonication Radiation ...
... class-action lawsuit was filed against Purina alleging that the company's Beneful brand of dog food contained propylene glycol ...
Otto Fuel II, a mixture of the low explosive propylene glycol dinitrate with a stabilizer, has also been tried in 37mm guns. In ...
Starting with propylene chlorohydrin, most of the world's supply of propylene oxide arises via this route. An intramolecular ... Its hydrolysis affords ethylene glycol. It is also used for sterilisation of medical instruments and materials. The reaction of ... Organic peroxides are used for the production of propylene oxide from propylene. Catalysts are required as well. Both t-butyl ... Other alkenes fail to react usefully, even propylene, though TS-1 supported Au catalysts can perform propylene epoxidation ...
Propylene glycol reduces water activity and acts as a plasticizing agent to give food its desired texture. Compared to canning ... Food ingredients are mixed with salt and/or sugar, and additives (such as propylene glycol and potassium sorbate) and then ...
Also included are minor cannabinoids and terpenoids, ethanol and propylene glycol excipients, and peppermint flavoring. The ...
... or propylene glycol alginate or any combination thereof in an amount not exceeding 0.5 percent, monoglycerides, mono- and ...
He also proposed using propylene glycol to dilute nicotine and placing it in a disposable plastic cartridge which serves as a ... ultrasound-emitting element to vaporise a pressurized jet of liquid containing nicotine diluted in a propylene glycol solution ...
Propylene glycol toxicity: A severe iatrogenic illness in intensive care unit patients receiving intravenous benzodiazepines. ...
... propylene glycol)- block -poly(ethylene glycol): enzyme free and label free sugar sensing in serum samples using resonance ... Kurdi, Riham El; Patra, Digambara (2018). "Tuning the surface of Au nanoparticles using poly(ethylene glycol)- block -poly( ...
... a mixture of water and antifreeze such as propylene glycol is used. A heat exchange fluid protects against freeze damage down ... to a locally determined risk temperature that depends on the proportion of propylene glycol in the mixture. The use of glycol ... The energy is then collected by cooling the plate with a working fluid, often water or glycol running in pipes attached to the ...
Propylene glycol is generally regarded as safe for use in food. Ethylene glycol has been found in at least 34, and propylene ... 57-55-6 Propylene Glycol, ATSDR, Agency for Toxic Substances and Disease Registry, DT, Division of Toxicology, ToxFAQs, ToxFAQs ... Exposure to large amounts of ethylene glycol can damage the kidneys, heart, and nervous system. ... glycol in at least 5, of the 1,416 National Priorities List sites identified by the Environmental Protection Agency (EPA). >, ...
OSHA previously had no exposure limit for propylene glycol dinitrate. The ACGIH recommends a TLV-TWA of 0.05 ppm, with a skin ... Propylene glycol dinitrate can also cause headache and incoordination.. The oral LD(50) value for the rat is between 480 and ... OSHA previously had no exposure limit for propylene glycol dinitrate. The ACGIH recommends a TLV-TWA of 0.05 ppm, with a skin ... OSHA is establishing an 8-hour TWA limit of 0.05 ppm for propylene glycol dinitrate. The Agency concludes that this limit will ...
PROPYLENE GLYCOL (UNII: 6DC9Q167V3) (PROPYLENE GLYCOL - UNII:6DC9Q167V3) PROPYLENE GLYCOL. 1034.2 g in 1 L. ... PROPYLENE GLYCOL- propylene glycol liquid Durvet, Inc.. Disclaimer: This drug has not been found by FDA to be safe and ... PROPYLENE GLYCOL propylene glycol liquid. Product Information. Product Type. OTC ANIMAL DRUG. Item Code (Source). NDC:30798-635 ...
Testing Status of Propylene glycol phenyl ether 14011. Testing Status of Propylene glycol phenyl ether 14011. CASRN: 770-35-4. ...
Standard operating procedure for determination of nicotine, glycerol and propylene glycol in e-liquids: WHO TobLabNet official ...
beverages or take products that contain alcohol or propylene glycol while you are taking secnidazole and for 2 days after your ... alcoholic beverages or take products with alcohol or propylene glycol while you are taking this medication and for 3 days ... Alcohol and propylene glycol may cause an upset stomach, vomiting, stomach cramps, ... ... Alcohol and propylene glycol along with secnidazole may cause nausea, vomiting, stomach ... ...
... "glycol"[All Fields]) OR "propylene glycol"[All Fields]). Search. ...
Mixture of the propylene glycol mono- and diesters of lauric (dodecanoic) acid. It contains not less than 70.0 percent of ... Propylene glycol dilaurate. Used as a lipid excipient in formulation of soft gelatin capsules ...
... propylene glycol, or antibiotic paste. da Silva JM, Andrade Junior CV, Zaia AA, Pessoa OF. da Silva JM, et al. Oral Surg Oral ...
Propylene glycol is a commonly used solvent for oral, intravenous, and topical pharmaceutical preparations. Although it is ... Severe propylene glycol toxicity secondary to use of anti-epileptics. Pillai U, Hothi JC, Bhat ZY. Pillai U, et al. Am J Ther. ... Recognition, treatment, and prevention of propylene glycol toxicity Tausif Zar et al. Semin Dial. 2007 May-Jun. ... Recognition, treatment, and prevention of propylene glycol toxicity Tausif Zar 1 , Charles Graeber, Mark A Perazella ...
Aerosolized propylene glycol (PG) was generated as log-normally distributed particulate clouds in different concentrations ... Non-clinical safety and pharmacokinetic evaluations of propylene glycol aerosol in Sprague-Dawley rats and Beagle dogs ... Aerosolized propylene glycol (PG) was generated as log-normally distributed particulate clouds in different concentrations ...
Learn about the veterinary topic of Propylene Glycol Toxicosis in Animals. Find specific details on this topic and related ... The oral LD50 of propylene glycol in dogs is ~9 mL/kg. In cats, ingestion of a diet containing 6%-12% propylene glycol can ... propylene glycol, when ingested, may be associated with a syndrome similar to the acute phase of ethylene glycol toxicosis. ... Ingestion of propylene glycol may result in false-positive ethylene glycol test kit results. ...
... lubricant and propylene glycol products in a variety of sizes. ...
Best Rated CBD Oil Does Not Contain Propylene Glycol*Best Rated CBD Oil Does Not Contain Propylene Glycol ... Best Rated CBD Oil Does Not Contain Propylene Glycol. To aid you out, Ive taken a look at hundreds of CBD brand names, taking ... The 5 Best CBD Oil Brands Reviewed for 2021.Best Rated CBD Oil Does Not Contain Propylene Glycol. If you remain in a great deal ... Which CBD Oil Works Best?Best Rated CBD Oil Does Not Contain Propylene Glycol. The CBD oil that functions ideal for you must ...
XIKAR® Propylene Glycol Solution 16oz, 3-pack. XIKAR PG solution (propylene glycol) is manufactured to our exact specifications ... mix: it is a perpetual solution, whose mix of propylene glycol and purified water is such that the propylene glycol biodegrades ... Propylene Glycol Solution 16oz, 3-pack becomes available - https://xikar.com/products/xikar-propylene-glycol-solution-16oz-3- ...
inquirePropylene Glycol Phenyl Ether CAS NO : 770-35-4;130879-97-9; MF : C9H12O2 PPH is nontoxic and environmental and has ... inquireEthylene Glycol Monophenyl Ether CAS NO : 122-99-6; MF : C8H10O2 EPH is a high boiling point solvent with faint rose- ...
These fully-formulated, propylene glycol-based products are manufactured from 100% renewable bio-based feedstock. This ... emissions and non-renewable energy consumption during the manufacturing process over conventionally made propylene glycol.. ...
Premixed Propylene Glycol. Buy by the Gallon / Drums / Totes. Buy online today! We sell to Everyone. Free Delivery. Order ... Premixed Propylene Glycol - 55 Gallons 20% to 50% Premixed Propylene Glycol - 5 Gallons 20% to 50% Premixed Propylene Glycol - ... Can anyone order Propylene Glycol?. There are no restriction on whom can order Propylene Glycol. We sell to all end users and ... How should I buy Propylene Glycol?. We always suggest purchasing Propylene Glycol in concentrated form. It is the most ...
Poly Propylene Glycol. About Poly Propylene Glycol. Enquire Now. Our team of experts are at the ready. Fill out the form below ... Propylene Glycol. POLY[OXY(METHYL-1,2-ETHANEDIYL)],.ALPHA.-HYDRO-.OMEGA.-HYDROXY-. Raypol 1020. Polyether Polyol. Propane-1,2- ...
... with 115 pages available at USD 2350 for single ... Section 1 Propylene Glycol Market Overview. 1.1 Propylene Glycol Market Scope. 1.2 COVID-19 Impact on Propylene Glycol Market. ... 3.1.4 ADM Propylene Glycol Business Profile. 3.1.5 ADM Propylene Glycol Product Specification. 3.2 BASF Propylene Glycol ... Chart ADM Propylene Glycol Business Profile. Table ADM Propylene Glycol Product Specification. Chart United States Propylene ...
Propylene glycol increased insulin and insulin-likegrowth factor-I, but glucose, urea and triglyceride did not vary. ... Thus, propylene glycol improved pregnancy rates after embryo-transfer, and progesterone, insulin and insulin-like-growth factor ... The objective of this study was to determine the effect of a sustained propylene glycol administration to recipients of frozen/ ... Heifers were treated with oral propylene glycol for the last 20 days before embryo transfer (n ¼ 142), and untreated as ...
Propylene Glycol Alginate (PGA) CAS 9005-37-2, an Alginate Ester, is a Food Additive used for Stabilization, Thickening and ... Propylene glycol alginate has colloidal properties, but because there is propylene glycol group in the molecule, it is ... Propylene glycol alginate PGA is more expensive and is often mixed with other colloids. Because the viscosity of PGA is lower ... The propylene glycol alginate produced by our company has stable performance and a wide range of uses, which can meet the ...
10 Scary Facts About Propylene Glycol In Food & Skin Care. Superfoodly. June 21, 2017. ...
Propylene Glycol is a highly effective humectant. It helps the hair absorb and retain moisture. In haircare products, it ... Propylene Glycol. Propylene Glycol is a highly effective humectant. It helps the hair absorb and retain moisture. In haircare ...
Just Flavors only supplies USP Grade Propylene Glycol (PG). This is the same PG used in cosmetics, personal care, and ... 5 LITER PROPYLENE GLYCOL EGP1,400.00. EGP1,260.00. 5 LITER PROPYLENE GLYCOL quantity. ... In e-liquids, Propylene Glycol (PG) is used to dilute liquid nicotine and enhance flavors. Notably, PG creates a throat hit ... Be the first to review "1/4 LITER PROPYLENE GLYCOL" Cancel reply. Your email address will not be published. Required fields are ...
Learn about Propylene Glycol, a multi-use lubrication for food-grade applications, antifreeze in automotive and many more ... Propylene Glycol Propylene Glycol. back *All Propylene Glycol. *Propylene Glycol Inhibited-Heat Transfer Fluid 100% Concentrate ... Propylene Glycol. What Is Propylene Glycol?. Propylene glycol is a synthetic liquid substance that absorbs water. Propylene ... has classified propylene glycol as an additive that is generally recognized as safe for use in food. Propylene glycol from ...
Get an instant quote for a PROPYLENE GLYCOL Tank. ... Get an instant quote for a PROPYLENE GLYCOL Tank. ... Doublewalltank.com › Chemicals › PROPYLENE GLYCOLPROPYLENE GLYCOL Tank. Chemical Compatibility of common Resins, Fittings, ... Doublewalltank.com › Chemicals › PROPYLENE GLYCOLPROPYLENE GLYCOL Tank. Chemical Compatibility of common Resins, Fittings, ... RESINS: Here is how PROPYLENE GLYCOL works with plastics used to make our PROPYLENE GLYCOL storage tanks. ...
PROPYLENE GLYCOL (UNII: 6DC9Q167V3) (PROPYLENE GLYCOL - UNII:6DC9Q167V3) PROPYLENE GLYCOL. 1 g in 100 mL. ... glycerin 0.3 % / propylene glycol 1 % Ophthalmic Solution. PSN. 2. 259195. glycerin 3 MG/ML / propylene glycol 10 MG/ML ... ARTIFICAL TEARS- glycerin and propylene glycol solution/ drops. To receive this label RSS feed. Copy the URL below and paste it ... ARTIFICAL TEARS- glycerin and propylene glycol solution/ drops. If this SPL contains inactivated NDCs listed by the FDA ...
  • Propylene glycol breaks down at the same rate as ethylene glycol, although it does not form harmful crystals when it breaks down. (cdc.gov)
  • It is used to absorb extra water and maintain Propylene glycol breaks down at the same rate as ethylene glycol, moisture in certain medicines, cosmetics, or food products. (cdc.gov)
  • Ethylene Glycol Toxicosis in Animals Ethylene glycol toxicosis is often fatal and primarily affects dogs and cats, though all species are susceptible. (merckvetmanual.com)
  • propylene glycol, when ingested, may be associated with a syndrome similar to the acute phase of ethylene glycol toxicosis. (merckvetmanual.com)
  • Ingestion of propylene glycol may result in false-positive ethylene glycol test kit results. (merckvetmanual.com)
  • Ethylene Glycol (Antifreeze) Poisoning Most ethylene glycol poisonings are associated with ingestion of radiator antifreeze. (merckvetmanual.com)
  • Ethylene glycol poisoning is. (merckvetmanual.com)
  • Propylene Glycol is commonly used as a substitute for Ethylene Glycol in low toxicity and environmentally safe antifreeze. (kellerheartt.com)
  • When the initiator is ethylene glycol or water the polymer is linear. (aspen-dentalclinic.com)
  • Polyethylene Glycol is made by polymerising ethylene glycol, the main ingredient in antifreeze solutions, and has a strong presence in the medical industry. (aspen-dentalclinic.com)
  • IPG is a hybrid organic acid / propylene glycol - based antifreeze concentrate for use in those cooling systems where the use of ethylene glycol is not desirable (eg food processing, etc. (power-up.net.au)
  • For ethylene glycol: Death may occur within the first 24 hours. (medlineplus.gov)
  • Propylene glycol is a clear liquid used in antifreeze and deicing solutions. (cdc.gov)
  • Propylene glycol is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food. (kellerheartt.com)
  • WebHere are a few facts about polyethylene glycol (the somewhat dangerous one): Polyethylene glycol is, in fact, used in antifreeze because it lowers the freezing In the literature, sensitizations to PEGs or macrogols, as immediate-type contact urticaria or more frequently allergic contact dermatitis are well known. (aspen-dentalclinic.com)
  • Aerosolized propylene glycol (PG) was generated as log-normally distributed particulate clouds in different concentrations using a novel capillary aerosol generator (CAG) and evaluated in a battery of non-clinical studies intended to assess its potential inhalation and systemic toxicity in 2 species before ICH-compliant "first-time-in-man" studies. (nih.gov)
  • Treatment of toxicity includes hemodialysis to effectively remove propylene glycol. (nih.gov)
  • Severe propylene glycol toxicity secondary to use of anti-epileptics. (nih.gov)
  • Propylene glycol It is a viscous, colourless, and odourless liquid with low toxicity. (aspen-dentalclinic.com)
  • Foods Containing Propylene Glycol In the beverage world, soft drinks, flavored teas, powdered drink mixes and alcoholic beverages may also contain propylene glycol. (aspen-dentalclinic.com)
  • Propylene glycol is a clear, colorless, slightly syrupy liquids at room temperature. (cdc.gov)
  • Propylene glycol is a clear, colorless, slightly syrupy liquids at products, using cosmetics, or taking medicine that contains it. (cdc.gov)
  • When freshly prepared, propylene glycol dinitrate is a colorless liquid with a disagreeable odor. (cdc.gov)
  • PG or propylene glycol is colorless, odorless, and almost tasteless and is one of the main ingredients used in eliquids. (aspen-dentalclinic.com)
  • It also contains glycerol or propylene glycol (PEG), which looks like smoke when you exhale. (nih.gov)
  • In the past few years, the Propylene Glycol market experienced a huge change under the influence of COVID-19 and Russia-Ukraine War, the global market size of Propylene Glycol reached 4955.8 million $ in 2022 from XXX in 2017 with a CAGR of xxx from 2017-2022. (reportsweb.com)
  • Publisher predicts that the global Propylene Glycol market size will reach 7138.0 million $in 2028 with a CAGR of xx% from 2022-2028. (reportsweb.com)
  • In e-liquids, Propylene Glycol (PG) is used to dilute liquid nicotine and enhance flavors. (justflavorseg.com)
  • Nicotine plus flavorings in a propylene glycol (PG) vehicle are the components of electronic cigarette liquids (e-liquids), which are vaporized and inhaled by the user. (cdc.gov)
  • Propylene Glycol is a key preservative in tobacco cigarettes, as well as a major ingredient in eLiquids and the cartridges used for E-Cigarettes. (kellerheartt.com)
  • Frequent skin exposure to propylene glycol can sometimes irritate the skin. (cdc.gov)
  • Propylene glycol is generally considered to be a safe chemical, and is not routinely tested for, unless specific exposure, such as to a medicine or cosmetic, can be linked with symptoms. (cdc.gov)
  • OSHA previously had no exposure limit for propylene glycol dinitrate. (cdc.gov)
  • Propylene glycol is practically odorless and tasteless. (cdc.gov)
  • alcoholic beverages or take products with alcohol or propylene glycol while you are taking this medication and for 3 days afterwards. (nih.gov)
  • ChemWorld is also a distributor of dipropylene glycol and other specialty chemicals. (chemworld.com)
  • Hawkins Is A Key Biobased Propylene Glycol Supplier & Distributor. (hawkinsinc.com)
  • 1997. Toxicological Profile for Propylene Glycol . (cdc.gov)
  • Treatment of propylene glycol toxicosis is largely supportive-the use of alcohol dehydrogenase inhibitors is not indicated. (merckvetmanual.com)
  • In humans, eight-hour exposures to 0.2 ppm or higher concentrations of propylene glycol dinitrate resulted in visual distortion and headache (Stewart, Peterson, Newton et al. (cdc.gov)
  • If you work in an industry that uses propylene glycol or products containing propylene glycol, you could be exposed by breathing or touching these substances. (cdc.gov)
  • These fully-formulated, propylene glycol-based products are manufactured from 100% renewable bio-based feedstock. (chempoint.com)
  • This production method results in a significant reduction in greenhouse gas (GHG) emissions and non-renewable energy consumption during the manufacturing process over conventionally made propylene glycol. (chempoint.com)
  • beverages or take products that contain alcohol or propylene glycol while you are taking secnidazole and for 2 days after your final dose. (nih.gov)
  • It is the most economical way of purchasing Propylene Glycol, but in those cases where the specification calls for premixed glycol, please visit our other site where we listed diluted forms of Premixed Propylene Glycol . (chemworld.com)
  • Prevention is best achieved by limiting the dose of propylene glycol infused. (nih.gov)
  • Removal of propylene glycol and correction of increased osmolar gap by hemodialysis in a patient on high dose lorazepam infusion therapy. (nih.gov)
  • Propylene glycol alginate is used in cold drinks, pharmaceuticals and other products for emulsification, thickening and stabilization, and is an excellent organic health product. (sdlookchem.com)
  • Propylene glycol is a commonly used solvent for oral, intravenous, and topical pharmaceutical preparations. (nih.gov)
  • Since Propylene Glycol is used to lower the freezing point of water, it's commonly used as a de-icer for airport runways and aircraft. (kellerheartt.com)
  • The objective of this study was to determine the effect of a sustained propylene glycol administration to recipients of frozen/thawed in vivo derived bovine embryos. (asturias.es)
  • Ex vivo (human skin) and in vivo (minipig) permeation of propylene glycol applied as topical crisaborole ointment, 2. (bvsalud.org)
  • Browse all the Propylene Glycol in Supaul on our website and place your bulk orders with us. (ryan-international.in)
  • As an eminent Propylene Glycol Dealer and Wholesaler in Supaul , we are available a phone call and click away to meet your bulk orders. (ryan-international.in)
  • New evidence demonstrates more clearly that it is possible to develop severe immediate hypersensitivity to macrogols, of which the most familiar form to most physicians is polyethylene glycol (PEG) 3350. (aspen-dentalclinic.com)
  • The Food and Drug Administration has classified propylene glycol as "generally recognized as safe," which means that it is acceptable for use in flavorings, drugs, and cosmetics, and as a direct food additive. (cdc.gov)
  • The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is "generally recognized as safe" for use in food. (cdc.gov)
  • You can be exposed to propylene glycol by eating food products, using cosmetics, or taking medicine that contains it. (cdc.gov)
  • Propylene glycol alginate can be used as food additive for emulsification, stabilization, foaming and thickening of food, and it is widely used in food, medicine and daily chemical industry. (sdlookchem.com)
  • Propylene glycol from Keller Heartt is food safe and certain varieties can also be certified Kosher. (kellerheartt.com)
  • It's approved for food applications (GRAS) and is the first propylene glycol to meet United States Pharmacopeia (USP) and USDA certified biobased product label standards. (hawkinsinc.com)
  • Chill-Pro Propylene Glycol is GRAS and meets FCC specifications for use in food plants. (hawkinsinc.com)
  • The majority of Propylene Glycol is used as chemical feedstock, during the production of unsaturated polyester resins - which produce sheet molding, printer toner and fiberglass wall panels. (kellerheartt.com)
  • It may exist in air in the vapor form, although ` If you work in an industry that uses propylene glycol or propylene glycol must be heated or briskly shaken to produce products containing propylene glycol, you could be exposed by a vapor. (cdc.gov)
  • People with Propylene-glycol allergy have a hypertensive reaction to all the above products and any other product with PG or even products manufactured by the same machine. (aspen-dentalclinic.com)
  • Propylene glycol is a synthetic liquid substance that absorbs water. (kellerheartt.com)
  • Propylene glycol increases the amount of acid in the body. (cdc.gov)
  • Mixture of the propylene glycol mono- and diesters of lauric (dodecanoic) acid. (imcdgroup.com)
  • Propylene glycol alginate has strong acid resistance, but poor alkaline resistance, and the viscosity is stable in pH3-4 for a long time. (sdlookchem.com)
  • Propylene glycol alginate has colloidal properties, but because there is propylene glycol group in the molecule, it is lipophilic and has good emulsification stability, so it is often used in lactic acid drinks, juice milk drinks and other foods with low pH range. (sdlookchem.com)
  • This fact sheet answers the most frequently asked health questions about about propylene glycol. (cdc.gov)
  • How can propylene glycol affect my health? (cdc.gov)
  • The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the EPA have not classified propylene glycol for carcinogenicity. (cdc.gov)
  • About half of the propylene glycol that enters the air will The Department of Health and Human Services (DHHS), the break down in 24-50 hours. (cdc.gov)
  • No comments except those from NIOSH were received on the health effects of propylene glycol dinitrate. (cdc.gov)
  • XIKAR PG solution (propylene glycol) is manufactured to our exact specifications. (xikar.com)
  • In cats, ingestion of a diet containing 6%-12% propylene glycol can result in Heinz body formation and decreased RBC survival. (merckvetmanual.com)
  • The oral LD 50 of propylene glycol in dogs is ~9 mL/kg. (merckvetmanual.com)
  • Heifers were treated with oral propylene glycol for the last 20 days before embryo transfer (n ¼ 142), and untreated as controls (n ¼ 133). (asturias.es)
  • We reported an anaphylaxis after oral intake and contact urticaria due to polyethylene glycols. (aspen-dentalclinic.com)
  • It may exist in air in the vapor form, although propylene glycol must be heated or briskly shaken to produce a vapor. (cdc.gov)
  • We always suggest purchasing Propylene Glycol in concentrated form. (chemworld.com)
  • Propylene glycol is also used to make polyester compounds and as a base for de-icing solutions. (kellerheartt.com)
  • Propylene glycol alginate is made from alginate extracted from natural seaweed by deep processing. (sdlookchem.com)
  • Show This to Your Doctor: Proof of Glycol Allergies, 11 Ways to Make Your Life With Glycol Allergies Easier, Resources for Finding Trade Names & Synonyms, Is it PEG? (aspen-dentalclinic.com)
  • Thus, propylene glycol improved pregnancy rates after embryo-transfer, and progesterone, insulin and insulin-like-growth factor-I are probably involved in this effect. (asturias.es)
  • Propylene glycol alginate has emulsifying property due to the presence of lipophilic group in the molecule, so it has unique foam stabilizing effect. (sdlookchem.com)
  • As an experienced propylene glycol alginate (PGA) manufacturer and supplier. (sdlookchem.com)
  • Is there a medical test to determine whether I have been exposed to propylene glycol? (cdc.gov)
  • Facing the complicated international situation, the future of the Propylene Glycol market is full of uncertain. (reportsweb.com)
  • We are well-recognized in the market for delivering premium quality Propylene Glycols that we source from reliable platforms. (ryan-international.in)
  • As with other contact allergies, once propylene glycol has been identified as a culprit allergen, education and avoidance are the cornerstone of treatment. (aspen-dentalclinic.com)
  • International Agency for Research on Cancer (IARC), and the ` It will break down within several days to a week in water and EPA have not classified propylene glycol for carcinogenicity. (cdc.gov)
  • For a reliable, consistent source of inhibited, biobased propylene glycol contact Hawkins for a propylene glycol quote. (hawkinsinc.com)
  • Part of the carboxyl group of alginate is esterified by propylene glycol (more than 90%), while the remaining 10% of the carboxyl group is free or neutralized by alkali. (sdlookchem.com)