Indole Alkaloids: Group of alkaloids containing a benzylpyrrole group (derived from TRYPTOPHAN)Secologanin Tryptamine Alkaloids: Compounds formed by condensation of secologanin with tryptamine resulting in a tetrahydro-beta-carboline which is processed further to a number of bioactive compounds. These are especially found in plants of the APOCYNACEAE; LOGANIACEAE; and RUBIACEAE families.Catharanthus: A plant genus of the family Apocynaceae. It is the source of VINCA ALKALOIDS, used in leukemia chemotherapy.Alkaloids: Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)Rauwolfia: A plant genus of the APOCYNACEAE or dogbane family. Alkaloids from plants in this genus have been used as tranquilizers and antihypertensive agents. RESERPINE is derived from R. serpentina.Aspidosperma: A plant genus of the family APOCYNACEAE. It contains ellipticine.Vinca Alkaloids: A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.Indoles: Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.Rubiaceae: The Madder plant family of the order Rubiales, subclass Asteridae, class Magnoliopsida includes important medicinal plants that provide QUININE; IPECAC; and COFFEE. They have opposite leaves and interpetiolar stipules.Alstonia: A plant genus of the family APOCYNACEAE. Members contain echitovenidine, echitamine, venenatine (an indole alkaloid), and anti-inflammatory triterpenoidsCarbon-Nitrogen Lyases: Enzymes that catalyze the cleavage of a carbon-nitrogen bond by means other than hydrolysis or oxidation. Subclasses are the AMMONIA-LYASES, the AMIDINE-LYASES, the amine-lyases, and other carbon-nitrogen lyases. EC 4.3.Ergot Alkaloids: Alkaloids originally isolated from the ergot fungus Claviceps purpurea (Hypocreaceae). They include compounds that are structurally related to ergoline (ERGOLINES) and ergotamine (ERGOTAMINES). Many of the ergot alkaloids act as alpha-adrenergic antagonists.Prenylation: Attachment of isoprenoids (TERPENES) to other compounds, especially PROTEINS and FLAVONOIDS.Lyngbya Toxins: Toxins isolated from any species of the seaweed Lyngbya or similar chemicals from other sources, including mollusks and micro-organisms. These have been found to be potent tumor promoters. They are biosynthesized from TRYPTOPHAN; VALINE; and METHIONINE nonribosomally (PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT).Tabernaemontana: A plant genus of the family APOCYNACEAE that contains bisindole alkaloids and IBOGAINE.Uncaria: A plant genus of the family RUBIACEAE. Members contain uncarine and other cytotoxic and hypotensive oxindole alkaloids.Iridoid Glucosides: A subclass of iridoid compounds that include a glucoside moiety, usually found at the C-1 position.Ibogaine: One of several indole alkaloids extracted from Tabernanthe iboga, Baill. It has a complex pharmacological profile, and interacts with multiple systems of neurotransmission. Ibogaine has psychoactive properties and appears to modulate tolerance to opiates.Apocynaceae: The dogbane family of the order Gentianales. Members of the family have milky, often poisonous juice, smooth-margined leaves, and flowers in clusters. Asclepiadacea (formerly the milkweed family) has been included since 1999 and before 1810.Monoterpenes: Compounds with a core of 10 carbons generally formed via the mevalonate pathway from the combination of 3,3-dimethylallyl pyrophosphate and isopentenyl pyrophosphate. They are cyclized and oxidized in a variety of ways. Due to the low molecular weight many of them exist in the form of essential oils (OILS, VOLATILE).Pyrrolizidine Alkaloids: A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.Psychotria: A plant genus of the family RUBIACEAE. Members contain psychotridine and brachycerine (indole alkaloids).Iridoids: A type of MONOTERPENES, derived from geraniol. They have the general form of cyclopentanopyran, but in some cases, one of the rings is broken as in the case of secoiridoid. They are different from the similarly named iridals (TRITERPENES).Tryptamines: Decarboxylated monoamine derivatives of TRYPTOPHAN.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Gelsemium: A plant genus of the family LOGANIACEAE (classified by some botanists as Gelsemiaceae). The sometimes used common name of trumpet flower is also used for DATURA.Mitragyna: A plant genus of the family RUBIACEAE. Members contain antimalarial (ANTIMALARIALS) and analgesic (ANALGESICS) indole alkaloids.Alocasia: A plant genus of the family ARACEAE. Members contain beta-glucosidases and trypsin inhibitors.Cinchona Alkaloids: Alkaloids extracted from various species of Cinchona.Plant Bark: The outer layer of the woody parts of plants.Glucosidases: Enzymes that hydrolyze O-glucosyl-compounds. (Enzyme Nomenclature, 1992) EC 3.2.1.-.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Amphibian Venoms: Venoms produced by frogs, toads, salamanders, etc. The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. The venoms have been used as arrow poisons and include bufogenin, bufotoxin, bufagin, bufotalin, histrionicotoxins, and pumiliotoxin.Berberine Alkaloids: A group of related plant alkaloids that contain the BERBERINE heterocyclic ring structure.Plant Leaves: Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)Plants, Medicinal: Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.Terpenes: A class of compounds composed of repeating 5-carbon units of HEMITERPENES.Angiosperms: Members of the group of vascular plants which bear flowers. They are differentiated from GYMNOSPERMS by their production of seeds within a closed chamber (OVARY, PLANT). The Angiosperms division is composed of two classes, the monocotyledons (Liliopsida) and dicotyledons (Magnoliopsida). Angiosperms represent approximately 80% of all known living plants.Amaryllidaceae Alkaloids: Alkaloids derived from TYRAMINE combined with 3,4-dihydroxybenzaldehyde via a norbelladine pathway, including GALANTAMINE, lycorine and crinine. They are found in the Amaryllidaceae (LILIACEAE) plant family.Cyclopentanes: A group of alicyclic hydrocarbons with the general formula R-C5H9.Oxylipins: Eighteen-carbon cyclopentyl polyunsaturated fatty acids derived from ALPHA-LINOLENIC ACID via an oxidative pathway analogous to the EICOSANOIDS in animals. Biosynthesis is inhibited by SALICYLATES. A key member, jasmonic acid of PLANTS, plays a similar role to ARACHIDONIC ACID in animals.Aspergillus: A genus of mitosporic fungi containing about 100 species and eleven different teleomorphs in the family Trichocomaceae.Aconitum: A plant genus of the family RANUNCULACEAE. Members contain a number of diterpenoid alkaloids including: aconitans, hypaconitine, ACONITINE, jesaconitine, ignavine, napelline, and mesaconitine. The common name of Wolfbane is similar to the common name for ARNICA.Magnetic Resonance Spectroscopy: Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).Biological Products: Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.Plant Roots: The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)Aporphines: Dibenzoquinolines derived in plants from (S)-reticuline (BENZYLISOQUINOLINES).Claviceps: A genus of ascomycetous fungi, family Clavicipitaceae, order Hypocreales, parasitic on various grasses (POACEAE). The sclerotia contain several toxic alkaloids. Claviceps purpurea on rye causes ergotism.Molecular Conformation: The characteristic three-dimensional shape of a molecule.Carbolines: A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.Benzylisoquinolines: ISOQUINOLINES with a benzyl substituent.Gene Expression Regulation, Plant: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants.Harmine: Alkaloid isolated from seeds of Peganum harmala L., Zygophyllaceae. It is identical to banisterine, or telepathine, from Banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western Amazon region from related plants. It has no therapeutic use, but (as banisterine) was hailed as a cure for postencephalitic Parkinson disease in the 1920's.Delphinium: A plant genus of the family RANUNCULACEAE. Members contain ACONITINE and other diterpenoid alkaloids.Tryptophan: An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.Plant Proteins: Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.Solanaceous Alkaloids: Alkaloids, mainly tropanes, elaborated by plants of the family Solanaceae, including Atropa, Hyoscyamus, Mandragora, Nicotiana, Solanum, etc. Some act as cholinergic antagonists; most are very toxic; many are used medicinally.Cyclization: Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Berberine: An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Neotyphodium: The anamorphic form of the fungus EPICHLOE. Many Neotyphodium species produce ERGOT ALKALOIDS.Coptis: A plant genus of the family RANUNCULACEAE. Members contain BERBERINE and other isoquinoline ALKALOIDS.Rutaceae: A plant family in the order Sapindales that grows in warmer regions and has conspicuous flowers.Tryptophanase: An enzyme that catalyzes the conversion of L-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring K+. It also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine, and other 3-substituted amino acids. (From Enzyme Nomenclature, 1992) EC 4.1.99.1.Plant Poisoning: Poisoning by the ingestion of plants or its leaves, berries, roots or stalks. The manifestations in both humans and animals vary in severity from mild to life threatening. In animals, especially domestic animals, it is usually the result of ingesting moldy or fermented forage.SkatoleErgotism: Poisoning caused by ingesting ergotized grain or by the misdirected or excessive use of ergot as a medicine.Lycopodium: A plant genus of the family LYCOPODIACEAE. Members contain ALKALOIDS. Lycopodium oil is obtained from L. clavatum.Ergotamine: A vasoconstrictor found in ergot of Central Europe. It is a serotonin agonist that has been used as an oxytocic agent and in the treatment of MIGRAINE DISORDERS.
Betina, V. (1984). Indole derived tremorgenic toxins. In: Mycotoxins Production, Isolation, Separation and Purification (Betina ... indole diterpenes, ergot alkaloids and peramine. Related compounds are found across the range of endophytic fungal associations ... In: Ergot Alkaloids and Related Compounds (Berde, B. & Schild, H.O., eds.) Berlin: Springer-Verlag. Rowan, D.D.; Hunt, M.B.; ... The terpenes and alkaloids are inducible defenses which act similarly to defensive compounds produced by plants and are highly ...
Crinine is an alkaloid of the Amaryllidaceae family, and its asymmetric total synthesis was one of the first using the aza-Cope ... It can be used to create many additional ring structures useful in synthesis, such as indolizidine cycles and indole rings. The ... Also significant is the relative ease of production of the reactants, which uses a Diels-Alder reaction paired with relatively ... These aza-tricyclic structures are found in the complex Stemona alkaloid family, as well as in potential drugs such as some ...
Martin, D. B. C.; Vanderwal, C. D. (2009). "Efficient Access to the Core of the Strychnos, Aspidosperma and Iboga Alkaloids. A ... A variation of the Zincke reaction has been applied in the synthesis of novel indoles: with cyanogen bromide mediated pyridine ... This solution has greatly simplified the production and purification of complex Zincke aldehydes. Zincke, Th.; Heuser, G.; ... This reaction was the key step in their total synthesis of norfluorocurarine, a Strychnos alkaloid. This strategy was also ...
In 1985, Gracie and Zarkov published a summary of their work with three beta-carboline, harmala alkaloid-containing plants, ... 5 Three Beta-Carboline Containing Plants as Potentiators of Synthetic DMT and Other Indole Psychedelics,Technical note from the ... Cusack, Carole; Norman, Alex (2012). Handbook of New Religions and Cultural Production. Leiden, Netherlands: BRILL. ISBN ...
Later work allowed unprotected indoles to be targeted through Brønsted acid activation of the indole. In the initial report on ... These alkaloids have been shown to enhance the rate of substrate hydrogenation by 10-100 times, such that less than one ... More recently, a 2001 review indicated that asymmetric hydrogenation accounted for 50% of production scale, 90% of pilot scale ... The asymmetric hydrogenation of indoles initially focused on N-protected indoles, where the protecting group could serve both ...
This alkaloid is isolated from a fungus, Helminthosporium dematioideum. Cytochalasin B was first described in 1967, when it had ... Cytochalasin B can also interact with the auxin indole-3-acetic acid which occurs in wheat coleoptile segments and maize roots ... Smith, G; O'Hara, P; Ridler, M. "The Production of Multinucleated Lymphocytes by Cytochalasin B. An Electron Microscopic Study ... 1980). "Effect of Cytochalasin B and Colchicine on the Motility and Growth of Yoshida Sarcoma Cells In Vitro". Sci Rep Res Inst ...
In 1924, A. H. Reginald Buller published a comprehensive description and analysis of the processes of spore production and ... A 1962 publication reported the presence of the biologically active indole compound tryptamine in C. micaceus, although the ... Brossi A. (1991). The Alkaloids: Chemistry and Pharmacology. 40. Amsterdam, The Netherlands: Elsevier. p. 298. ISBN 0-12-469540 ... Worthen LR, Stessel GJ, Youngken HW (1962). "The occurrence of indole compounds in Coprinus species". Economic Botany. 16 (4): ...
Martin, S. F.; Rueger, H.; Williamson, S. A.; Grzejszczak, S. (1987). "General strategies for the synthesis of indole alkaloids ... The Diels-Alder reaction is also employed in the production of vitamin B6. The work by Diels and Alder is described in a series ... The retro Diels-Alder reaction is used in the industrial production of cyclopentadiene. Cyclopentadiene is a precursor to ... Kozmin, S. A.; Rawal, V. H. (1998). "A General Strategy to Aspidosperma Alkaloids: Efficient, Stereocontrolled Synthesis of ...
"Antifouling properties of simple indole and purine alkaloids from the Mediterranean gorgonian Paramuricea clavata". Journal of ... In drying seeds, serotonin production is a way to get rid of the buildup of poisonous ammonia. The ammonia is collected and ... This is followed by oxidation by aldehyde dehydrogenase to 5-HIAA, the indole acetic acid derivative. The latter is then ... Alarcon, J (2008). "Biotransformation of indole derivatives by mycelial cultures". Zeitschrift für Naturforschung C. 63: 82. ...
In chemical terms, it is an alkaloid with a phenethylamine skeleton found in various plants in the genus Ephedra (family ... Use of stimulants may cause the body to reduce significantly its production of natural body chemicals that fulfill similar ... Khat contains a monoamine alkaloid called cathinone, a "keto-amphetamine", that is said to cause excitement, loss of appetite, ... Substituted amphetamines, which are also called phenylpropylamino alkaloids, are a diverse group of nitrogen-containing ...
Production of phenolic compounds by Spirulina maxima microalgae and their protective effects in vitro toward hepatotoxicity ... 2012). Organic Production and Food Quality: A Down to Earth Analysis. Wiley-Blackwell, Oxford, UK. ISBN 978-0-8138-1217-5 ... The green alga Botryococcus braunii is the subject of research into the natural production of butylated hydroxytoluene (BHT),[ ... The Arabidopsis regulatory gene for production of Anthocyanin Pigment 1 (AtPAP1) can be expressed in other plant species.[42] ...
"Antifouling properties of simple indole and purine alkaloids from the Mediterranean gorgonian Paramuricea clavata". Journal of ... In drying seeds, serotonin production is a way to get rid of the buildup of poisonous ammonia. The ammonia is collected and ... Alarcon J (2008). "Biotransformation of indole derivatives by mycelial cultures". Zeitschrift für Naturforschung C. 63: 82. doi ... There follows oxidation by aldehyde dehydrogenase to 5-HIAA, the indole acetic-acid derivative. The latter is then excreted by ...
... especially on isolation and conversion of its alkaloids. To date more... ... Cell Suspension Culture Indole Alkaloid Alkaloid Production Catharanthus Roseus Plant Cell Report These keywords were added by ... Cordell, G.A., The Bisindole Alkaloids. In: Indoles. The Monoterpenoid Indole Alkaloids (Saxton, J.E. Ed.), p. 539. New York: ... Alkaloid Production in Catharanthus roseus (L.). G. Don Cell Cultures. XIII. Effects of Bioregulators on Indole Alkaloid ...
C. Spalla, Production of ergot alkaloids by fermentation, in: "Indole and Biogenetically Related Alkaloids," J.D. Phillipson ... Alkaloid production in Catharanthus roseus (L) G. Don. VI. Variation in alkaloid spectra of cell lines derived from one single ... Protoplast Fusion Ergot Alkaloid Cell Wall Formation Cytoplasmic Organelle Membrane Fragment These keywords were added by ... An immunofluorescence microscopic and ultrastructural study, Protoplasma 105:27-43 (1980).CrossRefGoogle Scholar ...
Agrobacterlum rhizogenes indole alkaloids Rauvolfia serpentina transgenic plants Abbreviations. MS. Murashige & Skoogs basal ... Kamada H, Okamura M, Satak M, Harada EH & Shimomura K (1986) Alkaloid production by hairy root cultures in Atropa belladonna ( ... Differentiation and alkaloid production. Biol. Plant. (Praha). 29: 241-246Google Scholar ... Roja PC, Benjamin BD, Heble MR & Chadha MS (1984) Indole alkaloids from multiple shoot cultures of Rauwolfia serpentina. Planta ...
Growth of seedlings in the dark resulted in an early ubiquitous accumulation of tabersonine as a major alkaloid and in the ... Alkaloid profiles as well as tryptophan decarboxylase and acetyl-CoA: deacetylvindole 0-acetyltransferase were monitored. ... Alkaloid Production in Catharanthus roseus Cell Cultures. III. Catharanthine and Other Alkaloids from the 200GW Cell Line (1980 ... Total synthesis of indole and dihydroindole alkaloids. IX. Studies on the synthesis of bisindole alkaloids in the vinblastine- ...
Alkaloid production in Catharanthus roseus (L.) G. Don cell cultures. XIII. Effects of bioregulators on indole alkaloid ... Indole alkaloid biosynthesis. Heterocycles. 1981; 15(2): 1257-74. [120] Kunakh VA , Alpatova LK. Rauwolfia serpentina cell ... 64] St?ckigt J, Pfitzner A, Firl J. Indole alkaloids from cell suspension cultures of Rauwolfia serpentina benth. Plant Cell ... The effect of a range of auxins and cytokinins on the production of quinoline alkaloids. Planta Medica. 1986;52(03):226-9. ...
Establishment, cultivation and optimization of hairy roots of Catharanthus roseus for the synthesis of indole alkaloids Bhadra ... Characterization of the acetone production pathway genes from Clostridium acetobutylicum ATCC 824 Petersen, Daniel James (1991) ... I used sapling population data collected since 1980 to investigate how canopy disturbance interacts with chronic understory ...
What is indoles? Meaning of indoles as a legal term. What does indoles mean in law? ... Definition of indoles in the Legal Dictionary - by Free online English dictionary and encyclopedia. ... He continued the synthetic studies on indole alkaloids, added several new methodologies and new indole derivatives and ... Indole-producing bacteria from the biosynthetic organs of a muricid mollusc could contribute to Tyrian purple production ...
... unlike the mechanisms of biosynthesis of other plant alkaloids, such as tropane, isoquinoline, and indole alkaloids (De Luca ... Lysine Decarboxylase Catalyzes the First Step of Quinolizidine Alkaloid Biosynthesis and Coevolved with Alkaloid Production in ... Lysine Decarboxylase Catalyzes the First Step of Quinolizidine Alkaloid Biosynthesis and Coevolved with Alkaloid Production in ... Lysine Decarboxylase Catalyzes the First Step of Quinolizidine Alkaloid Biosynthesis and Coevolved with Alkaloid Production in ...
In addition, in plants, iridoids serve as building blocks for monoterpenoid indole alkaloids with broad therapeutic ... Indole alkaloids from Catharanthus roseus: bioproduction and their effect on human health. Molecules 2015;20:2973-3000. PubMed ... Pheromone production in bark beetles. Insect Biochem Mol Biol 2010;40:699-712. CrossrefPubMedGoogle Scholar ... The biosynthesis and genetic engineering of bioactive indole alkaloids in plants. J Plant Biol 2016;59:203-14. CrossrefGoogle ...
Betina, V. (1984). Indole derived tremorgenic toxins. In: Mycotoxins Production, Isolation, Separation and Purification (Betina ... indole diterpenes, ergot alkaloids and peramine. Related compounds are found across the range of endophytic fungal associations ... In: Ergot Alkaloids and Related Compounds (Berde, B. & Schild, H.O., eds.) Berlin: Springer-Verlag. Rowan, D.D.; Hunt, M.B.; ... The terpenes and alkaloids are inducible defenses which act similarly to defensive compounds produced by plants and are highly ...
... indole-1-acetic acid nucleus bearing a substituent in position 1 and 4. The nucleus may be optionally substituted at position 8 ... Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b] ... Derivatives of iboga alkaloids US3516989A (en) 1970-06-23. Intermediates for total synthesis of iboga alkaloids and means of ... Condensed pyrrolinone derivatives, their production and use US4443605A (en) 1984-04-17. 7β-Arylalkyl-6α, 7 α-oxymethylene-3- ...
Seki, "Studies on the Morphine Alkaloids . . . ", vol. 84, No. 7, p. 626-631. Seki, "Studies on the Morphine Alkaloids ... Method for the production of amines by reductive amination of carbonyl compounds under transfer-hydrogenation conditions. 2007- ... Spadoni et al., "2-[N-Acylamino(C,-C3)alkyl)indoles as MT, . . . ", J. Med. Chem., 1998, 41, p. 3624-3634. Tolkachev et al., " ... Chemistry of opium alkaloids, Part IV)", Reel. Tray. Chim. Pays-Bas, 1976,75, p. 184-188. Bognar et al., Izvestiya po Khimiya, ...
MANDINAVEITIA, A.; VALENCIA, E.; BERMEJO, J.; GONZALEZ, A.G. Indole alkaloids from Rauwolfia sprucei. Biochem. Syst. Ecol., v. ... growth and alkaloid production. Plant Cell Tissue Organ. Cult., v.54, p.61-63, 1998. [ Links ]. ... Rauwolfia alkaloids. IV. Isolation of reserpine and other alkaloids from Rauwolfia sellowii Muell. Argov. J. Am. Chem. Soc., v. ... KATO, L.; BRAGA, R.M.; KOCH, I.; KINOSHITA, L.S. Indole alkaloids from Rauvolfia bahiensis A.DC. (Apocynaceae). Phytochemistry ...
Obviously, the extracellular metabolites from industrial microalgae have long been neglected in the development of production ... Bromoanaindolone a brominated indole alkaloid isolated from the culture medium of the cyanobacterium Anabaena constricta may ... Bremus, C.; Herrmann, U.; Bringer-Meyer, S.; Sahm, H. The use of microorganisms in l-ascorbic acid production. J. Biotechnol. ... Alkaloids. Alkaloids are frequently associated with allelopathy, especially in higher plants [142]. However, some metabolites ...
Streptomycindole, an indole alkaloid from a marine Streptomyces sp. DA22 associated with South China Sea sponge Craniella ... Teng, W. L., Khor, E., Tan, T. K., Lim, L. Y. & Tan, S. C. Concurrent production of chitin from shrimp shells and fungi. ... Particularly, members in Penicillium are known for their biotechnological potential in the production of proteases72. In our ...
The primary alkaloid arecoline is the neuro-active agent in the nut along with small amounts of the alkaloids arecaidine and ... The wear might have been caused by the halt of bowl production to conserve energy during drought and famine. Pollen grains were ... al 1998). The indole hallucinogen N, N-dimethyltryptamine is naturally present in many North American Acacia species ( ... 1982). Alkaloids of Duboisia hopwoodii. Phytochemistry 21:449-. 22. 451. DOI: 10.1016/S0031-9422(00)95286-5. 23. Mann, J. (1992 ...
Biosynthesis of Monoterpene Indole Alkaloids MIA Last Updated on Thu, 18 Apr 2019 , Plant Development ... These molecules are part of the large array of MIA Anticancer Anticancer Blocking an undesired production of alkaloid may be ... Production of Novel Carbohydrates in Transgenic Plants Last Updated on Fri, 28 Sep 2018 , Plant Metabolism ... Last Updated on Wed, 24 Oct 2018 , Soybean Production It can be processed into a number of fermented and non-fermented food ...
Proksch, P, Ebel, R 2002Ecological significance of alkaloids from marine invertebratesRoberts, MFWink, M eds. Alkaloids, ... Kobayashi, M, Aoki, S, Gato, K, Matsunami, K, Kurosu, M, Kitagawa, 1 1994Trisindoline, a new antibiotic indole trimer, produced ... HC 2000Application of cell culture for the production of bioactive compounds from sponges: synthesis of avarol by primmorphs ... Salmoun, M, Devijver, C, Daloze, D, Braekman, JC, Soest, RWM 20025-Hydroxytryptamine-derived alkaloids from two marine sponges ...
Although, the accumulation of indole alkaloid metabolites in sugarcane has not been so far reported, the unexpected finding of ... Metabolic engineering for the production of isoflavones in non-legume dicotyledon and monocotyledon tissues may provide ... 1988). The flavonoids: Advances in research since 1980. New York: Chapman & Hall. [ Links ]. Hata, S., Sanmiya, K., Kouchi, H ... Mabry T.J., and Ulubelen A. (1980). Chemistry and utilization of phenylpropanoids including flavonoids, coumarins, and lignans ...
... ii cytotoxic plex biological an architectonic macrolide library based on a c2 symmetric detoxification of indole by an indole ... of poly bisphenol a carbonate under mild characterization of electrically evoked field potentials in the nicotine alkaloids as ... a approved for public snail1 driven plasticity of epithelial and mesenchymal cells polyhydroxyalkanoates pha production by ... in the protein secondary cochlear gene therapy with ancestral aav in adult mice plete towards columbia paleomagnetism of 1980- ...
Anthranilate synthase (AS) is a key enzyme in the synthesis of tryptophan (Trp), indole-3-acetic acid, and indole alkaloids. ... 1996) Involvement of jasmonic acid in elicitor-induced phytoalexin production in suspension-cultured rice cells. Plant Physiol ... 1997) A deletion in an indole synthase gene is responsible for the DIMBOA-deficient phenotype of bxbx maize. Proc Natl Acad Sci ... It might, therefore, be expected that the AS enzymes not linked to alkaloid synthesis, such as those encoded by ASα2 and ...
Salvadoricine, an indole alkaloid, has been isolated from S. persica leaves (Malik et al. 1987). Volatile oils from the leaves ... In seed potato production, the contamination of seed tubers with soft rot bacteria (Pérombelon 2002; Toth et al. 2003), is one ... Al-Bagieh, N. H. (1998). "Effect of benzylisothiocyanate on the growth and acid production of Candida albicans," Biomed. Lett. ... Malik, S., Ahmad, S. S., Haider, S. I., and Muzaffar, A. (1987). "Salvadoricine, a new alkaloid from the leaves of Salvadora ...
Fungal secondary metabolites are mainly polyketides, non-ribosomal peptides, terpenes, and indole alkaloids, and the genes ... Figure 3. Deletion of VdMcm1 leads to reduced conidial production and abnormal conidial morphology. (A) Conidial production of ... Production of conidia in ΔVdMcm1-5 was decreased by 80% compared with that in the wild-type and complemented strains (Figure 3A ... In addition, Con7 deletion mutants in V. dahliae and F. oxysporum were reduced in the conidial production compared with the ...
Christiansen, A.L.; Rasmussen, K.E. Analysis of indole alkaloids in Norwegian Psilocybe semilanceata using high-performance ... Mass data were collected in the product ion scan mode. All solvents were of LC-MS grade. ... The studies the acute toxicity of fungal extracts containing psilocin and other indole alkaloids showed similar biological ... This phenomenon could be related to the synergistic effect of the other indole hallucinogenic alkaloids determined in ...
Natural aplysinopsins differ in the bromination pattern of the indole ring, variation in the structure of the C ring, including ... NO is a reactive molecule with one unoccupied electron, therefore its excessive production causes many diseases, e.g. ... Aplysinopsins - Marine Indole Alkaloids: Chemistry, Bioactivity and Ecological Significance. Dobroslawa Bialonska 1,3 and ... Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control ...
  • Katz et al disclosed 1,3,4,9-tetrahydropyrano[3,4-b]indoles having analgesic and anti-inflammatory activity but with substituents differing from those of the present invention. (google.com)
  • 10. "A Facile Reduction of Indoles by Diborane in Glacial Acetic Acid," J.T. Eaton and G.W. Gribble, 6th Northeast Regional American Chemical Society Meeting, Burlington, Vermont, August 18-21, 1974. (dartmouth.edu)
  • These 100 most important medicines from green plants are derived from only 41 species, with several of the alkaloid-producing plants contributing more than one compound. (dhushara.com)
  • Transgenic tobacco ( Nicotiana tabacum ) suspension cells and hairy roots produced enhanced levels of cadaverine-derived alkaloids, and transgenic Arabidopsis plants expressing (La- L/ODC ) produced enhanced levels of cadaverine, indicating the involvement of this enzyme in lysine decarboxylation to form cadaverine. (plantcell.org)
  • 693) note that this approach does not account for antagonistic behavior of ortho-substituted PCBs or the agonistic or antagonistic behavior and toxicity of non-chlorinated AhR ligands such as polyaromatic hydrocarbons, indoles , and flavonoids. (thefreedictionary.com)
  • 26. "A Convergent Approach to Ellipticine and Isoellipticine via New Indole Lithiation Methodology," M.G. Saulnier and G.W. Gribble, 11th Northeast Regional American Chemical Society Meeting, Rochester, New York, October 18-21, 1981. (dartmouth.edu)
  • The most notable of these therapeutic alkaloids are the antileukemic drugs vinblastine ( 1 ) and vincristine ( 2 ), the antihypertensive ajmalicine ( 3 ) used in combination with reserpine, and serpentine ( 4 ) which has a sedative effect. (springer.com)
  • I. (3 + 2) Cycloaddition Reactions of Oxyallyl Cationic Intermediates with Indoles Cyclopenta- and cyclohexa[b]indolines are ubiquitous molecular skeletons in natural products and pharmaceutical agents. (dartmouth.edu)
  • Alkaloids are one of the most diverse groups of natural products and are found in ~20% of plant species. (plantcell.org)
  • The arsenal of genes associated with necrotrophic processes is similar between the species, including genes involved in plant cell wall degradation and oxalic acid production. (plos.org)
  • β-Carboline is a key pharmacophore present in a large number of natural tricyclic alkaloids, which can be found in numerous plants and animals, exhibiting potent biological activities [1- (scribd.com)
  • As a key member of the β-carboline family, its structural variant tricyclic β-carbolinone (9H-pyrido[3,4-b]indol-1(2H)-one derivative or β-carbolin-1-one, Figure 1) has served as an important intermediate for the preparation of complex alkaloids [11-and has been found to possess potent bioactivities. (scribd.com)
  • So far, however, attempts to produce these alkaloids economically by the normal methods of synthetic organic chemistry have not given satisfactory results. (springer.com)
  • 18, 189 (1975) disclosed the chemistry and anti-inflammatory activity of related 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids. (google.com)
  • THE DISTINGUISHED PHARMACOGNOSIST Norman R. Farnsworth, indicates that in 1980 a quarter of the prescriptions dispensed from community pharmacies in the United States contained active principles from the higher plants - these chemicals numbering about 100. (dhushara.com)
  • 8. "A New Reduction of Indoles and Reductive-Alkylation of Amines," G.W. Gribble , 167th American Chemical Society Meeting, Los Angeles, California, April 1-5, 1974. (dartmouth.edu)
  • plants contain alkaloids used in modern herbal supplements to suppress hunger. (ispub.com)
  • Thus DPS has many advantages and can be used for large scale quality production of commercial plants in reduced time, cost and labour, which ultimately reduced the production cost of the farmer. (scholarena.co)
  • To understand salt adaptation strategies of plants, it is central to extend agricultural production to salt-affected soils. (paperity.org)
  • In the past decades transition-metal-catalyzed coupling reactions of aryl halides with all types of nucleophiles have emerged as the most important tool for the production of substituted arenes. (docme.ru)
  • So far, biomass-based production of industrial microalgae has been widely applied in the fields from food and feed to high-value chemicals for pharmaceutical and ecological applications [ 2 , 3 , 4 ]. (mdpi.com)
  • Flores HE (1986) Use of plant cell and organ culture in the production of biological chemicals. (springer.com)
  • Yamamoto O & Yamada Y (1986) Production of reserpine and its optimisation in cultured Rauvolfia serpentina Benth. (springer.com)
  • These were essentially the same molecules except that: (1) the phosphoryl or hydroxy group at the top of the indole ring was moved around to other ring positions, and (2) different numbers of methyl groups (CH 3 ) and other carbon chains were added to the side chains and to the nitrogen on the indole ring to see how these changes would affect psychoactivity. (thefullwiki.org)
  • Plant cell culture for production of natural ingredients. (org.ua)
  • Natural aplysinopsins differ in the bromination pattern of the indole ring, variation in the structure of the C ring, including the number and position of N -methylation, the presence and configuration of the C-8-C-1′ double bond, and the oxidation state of the 2-aminoimidazoline fragment. (mdpi.com)