Injections: Introduction of substances into the body using a needle and syringe.Injections, Intramuscular: Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it.Injections, Intravenous: Injections made into a vein for therapeutic or experimental purposes.Injections, Intralesional: Injections introduced directly into localized lesions.Injections, Subcutaneous: Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.Injections, Intra-Articular: Methods of delivering drugs into a joint space.Injections, Intraperitoneal: Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall.Injections, Intradermal: The forcing into the skin of liquid medication, nutrient, or other fluid through a hollow needle, piercing the top skin layer.Injections, Epidural: The injection of drugs, most often analgesics, into the spinal canal without puncturing the dura mater.Injections, Intraventricular: Injections into the cerebral ventricles.Injections, Intra-Arterial: Delivery of drugs into an artery.Intravitreal Injections: The administration of substances into the VITREOUS BODY of the eye with a hypodermic syringe.Injections, Spinal: Introduction of therapeutic agents into the spinal region using a needle and syringe.Injections, Jet: The injection of solutions into the skin by compressed air devices so that only the solution pierces the skin.Injections, Intraocular: The administration of substances into the eye with a hypodermic syringe.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Flow Injection Analysis: The analysis of a chemical substance by inserting a sample into a carrier stream of reagent using a sample injection valve that propels the sample downstream where mixing occurs in a coiled tube, then passes into a flow-through detector and a recorder or other data handling device.Microinjections: The injection of very small amounts of fluid, often with the aid of a microscope and microsyringes.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Substance Abuse, Intravenous: Abuse, overuse, or misuse of a substance by its injection into a vein.Sperm Injections, Intracytoplasmic: An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).Syringes: Instruments used for injecting or withdrawing fluids. (Stedman, 25th ed)Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Mice, Inbred C57BLNeedles: Sharp instruments used for puncturing or suturing.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Anesthetics, Local: Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.Vitreous Body: The transparent, semigelatinous substance that fills the cavity behind the CRYSTALLINE LENS of the EYE and in front of the RETINA. It is contained in a thin hyaloid membrane and forms about four fifths of the optic globe.Triamcinolone Acetonide: An esterified form of TRIAMCINOLONE. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Triamcinolone: A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Mice, Inbred BALB CNeuromuscular Agents: Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (NEUROMUSCULAR BLOCKING AGENTS), and drugs that act centrally as skeletal muscle relaxants (MUSCLE RELAXANTS, CENTRAL). Drugs used in the treatment of movement disorders are ANTI-DYSKINESIA AGENTS.Botulinum Toxins, Type A: A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.Rats, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Genetic Therapy: Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.Pain Measurement: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.Needle Sharing: Usage of a single needle among two or more people for injecting drugs. Needle sharing is a high-risk behavior for contracting infectious disease.Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Genetic Vectors: DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Contrast Media: Substances used to allow enhanced visualization of tissues.Neoplasm Transplantation: Experimental transplantation of neoplasms in laboratory animals for research purposes.Drug Administration Routes: The various ways of administering a drug or other chemical to a site in a patient or animal from where the chemical is absorbed into the blood and delivered to the target tissue.Gene Transfer Techniques: The introduction of functional (usually cloned) GENES into cells. A variety of techniques and naturally occurring processes are used for the gene transfer such as cell hybridization, LIPOSOMES or microcell-mediated gene transfer, ELECTROPORATION, chromosome-mediated gene transfer, TRANSFECTION, and GENETIC TRANSDUCTION. Gene transfer may result in genetically transformed cells and individual organisms.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Spleen: An encapsulated lymphatic organ through which venous blood filters.Behavior, Animal: The observable response an animal makes to any situation.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Anti-Dyskinesia Agents: Drugs used in the treatment of movement disorders. Most of these act centrally on dopaminergic or cholinergic systems. Among the most important clinically are those used for the treatment of Parkinson disease (ANTIPARKINSON AGENTS) and those for the tardive dyskinesias.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Mice, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.Mice, Nude: Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.Radiopharmaceuticals: Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Oocytes: Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).Drug Users: People who take drugs for a non-therapeutic or non-medical effect. The drugs may be legal or illegal, but their use often results in adverse medical, legal, or social consequences for the users.Mice, Inbred ICRLipopolysaccharides: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)Iodine Radioisotopes: Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.Disposable Equipment: Apparatus, devices, or supplies intended for one-time or temporary use.Adenoviridae: A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.Animals, Newborn: Refers to animals in the period of time just after birth.Freund's Adjuvant: An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.Hyperalgesia: An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.Anti-Inflammatory Agents: Substances that reduce or suppress INFLAMMATION.Viscosupplements: Viscoelastic solutions that are injected into JOINTS in order to alleviate symptoms of joint-related disorders such as OSTEOARTHRITIS.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Sheep: Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Neoplasms, Experimental: Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Rats, Inbred LewAnalysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Progesterone: The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.Needle-Exchange Programs: Organized services for exchange of sterile needles and syringes used for injections as a potential means of reducing the transmission of infectious diseases.Luteinizing Hormone: A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.Body Temperature: The measure of the level of heat of a human or animal.Nerve Block: Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.Fertilization in Vitro: An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.Autoradiography: The making of a radiograph of an object or tissue by recording on a photographic plate the radiation emitted by radioactive material within the object. (Dorland, 27th ed)Sclerosing Solutions: Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE.Estradiol: The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.Skin: The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.Spinal Cord: A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Metabolic Clearance Rate: Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.Carrageenan: A water-soluble extractive mixture of sulfated polysaccharides from RED ALGAE. Chief sources are the Irish moss CHONDRUS CRISPUS (Carrageen), and Gigartina stellata. It is used as a stabilizer, for suspending COCOA in chocolate manufacture, and to clarify BEVERAGES.Cats: The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)Injections, Intralymphatic: Injections into the lymph nodes or the lymphatic system.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Dependovirus: A genus of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, which are dependent on a coinfection with helper adenoviruses or herpesviruses for their efficient replication. The type species is Adeno-associated virus 2.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.Analgesics: Compounds capable of relieving pain without the loss of CONSCIOUSNESS.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Cisterna Magna: One of three principal openings in the SUBARACHNOID SPACE. They are also known as cerebellomedullary cistern, and collectively as cisterns.Equipment Reuse: Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.Immunization: Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).Retina: The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.Mice, Inbred C3HHypothalamus: Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.Morphine: The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.Methylprednisolone: A PREDNISOLONE derivative with similar anti-inflammatory action.Rats, Inbred F344Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Anesthesia, Local: A blocking of nerve conduction to a specific area by an injection of an anesthetic agent.Cell Count: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Organ Size: The measurement of an organ in volume, mass, or heaviness.Technetium: The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, atomic number 43, and atomic weight 98.91. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.Bupivacaine: A widely used local anesthetic agent.Hindlimb: Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Dextrans: A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.Spermatozoa: Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.Gonadotropin-Releasing Hormone: A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.Microspheres: Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.Cerebral Ventricles: Four CSF-filled (see CEREBROSPINAL FLUID) cavities within the cerebral hemispheres (LATERAL VENTRICLES), in the midline (THIRD VENTRICLE) and within the PONS and MEDULLA OBLONGATA (FOURTH VENTRICLE).Motor Activity: The physical activity of a human or an animal as a behavioral phenomenon.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Diabetes Mellitus, Experimental: Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.Antibody Formation: The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.Steroids: A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)Endotoxins: Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.Kinetics: The rate dynamics in chemical or physical systems.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Radioisotopes: Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Half-Life: The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.Transplantation, Heterologous: Transplantation between animals of different species.Fluoroscopy: Production of an image when x-rays strike a fluorescent screen.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Adrenal Cortex HormonesMice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Capsaicin: An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Botulinum Toxins: Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.Radiculopathy: Disease involving a spinal nerve root (see SPINAL NERVE ROOTS) which may result from compression related to INTERVERTEBRAL DISK DISPLACEMENT; SPINAL CORD INJURIES; SPINAL DISEASES; and other conditions. Clinical manifestations include radicular pain, weakness, and sensory loss referable to structures innervated by the involved nerve root.Naloxone: A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.Cocaine: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.Anesthesia, Dental: A range of methods used to reduce pain and anxiety during dental procedures.Capillary Permeability: The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.Hyaluronic Acid: A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Medical Waste Disposal: Management, removal, and elimination of biologic, infectious, pathologic, and dental waste. The concept includes blood, mucus, tissue removed at surgery or autopsy, soiled surgical dressings, and other materials requiring special control and handling. Disposal may take place where the waste is generated or elsewhere.Organotechnetium Compounds: Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.Growth Hormone: A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.Ovulation: The discharge of an OVUM from a rupturing follicle in the OVARY.Angiogenesis Inhibitors: Agents and endogenous substances that antagonize or inhibit the development of new blood vessels.Drugs, Chinese Herbal: Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.Embryo Transfer: The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Heart Rate: The number of times the HEART VENTRICLES contract per unit of time, usually per minute.Lymph Nodes: They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.Ethanol: A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.Serotonin: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.Mice, SCID: Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Adjuvants, Immunologic: Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.Follicle Stimulating Hormone: A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.Electric Stimulation: Use of electric potential or currents to elicit biological responses.Epinephrine: The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.Analgesics, Opioid: Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.Coloring Agents: Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.Delayed-Action Preparations: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.Cosmetic Techniques: Procedures for the improvement or enhancement of the appearance of the visible parts of the body.Indium Radioisotopes: Unstable isotopes of indium that decay or disintegrate emitting radiation. In atoms with atomic weights 106-112, 113m, 114, and 116-124 are radioactive indium isotopes.Horseradish Peroxidase: An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology.Dopamine: One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.Nociceptors: Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.Liposomes: Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.Blood Glucose: Glucose in blood.Estrus: The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.Sodium Chloride: A ubiquitous sodium salt that is commonly used to season food.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Enbucrilate: A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental.Organometallic Compounds: A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)Sclerotherapy: Treatment of varicose veins, hemorrhoids, gastric and esophageal varices, and peptic ulcer hemorrhage by injection or infusion of chemical agents which cause localized thrombosis and eventual fibrosis and obliteration of the vessels.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Microscopy, Electron: Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.Macrophages: The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.Arthritis, Experimental: ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.Chorionic Gonadotropin: A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).Mice, Inbred DBAGuinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Drug Carriers: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.Action Potentials: Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.Medulla Oblongata: The lower portion of the BRAIN STEM. It is inferior to the PONS and anterior to the CEREBELLUM. Medulla oblongata serves as a relay station between the brain and the spinal cord, and contains centers for regulating respiratory, vasomotor, cardiac, and reflex activities.
He said: "The writing process for the new Metallica album has begun. We've been in the studio with Rick Rubin, working on a ... Kennelty, Greg (March 11, 2016). "Metallica Hints At "Real, Heavy" New Album In The Second Half Of 2016". Metal Injection. ... Kennelty, Greg (February 8, 2016). "Metallica Nearing The End Of Recording Process For New Album, Allude To A 2016 Release". ... James Hetfield said that the band was nearing the end of the recording process, and Ulrich said that the album would be ...
"The Process of Human Extermination: Review by Phil Freeman". AllMusic. Retrieved July 2, 2014. Gregory Heaney. Fit for an ... AllMusic "FIT FOR AN AUTOPSY Has Been "Nate Johnsoned," Announce New Vocalist". Metal Injection. April 16, 2014. Fit for an ... Along with this, they have announced that they are in the writing process for a new album. This third album, named Absolute ... In 2011, Fit for an Autopsy released their first full-length LP, The Process of Human Extermination. In September 2013 the band ...
Application of insulation to the barrels of every injection molding machine. This reduced 40-50% of the total process energy ... low and high volume production injection molding and secondary processes. HARBEC was initially established in 1977 as a ... All-electric presses have lowered energy costs by up to 50% and have increased processing speed and cycle time. Use of low- ... Maniscalco, Michelle (2002-04-01). "Virtual design team speeds product to very real market". Injection Molding Magazine. [ ...
Two-shot injection molding: TPV can be combined with polymers through several types of multi-shot injection molding processes. ... Injection molding: Santoprene TPV grades can be processed using conventional thermoplastics injection-molding equipment at ... Santoprene TPV can be processed using conventional thermoplastic processes such as injection molding, blow molding and ... exxonmobilchemical.com Processing Santoprene TPV. Exxonmobilchemical.com. Retrieved on 2016-01-28. Santoprene TPV Injection ...
hidden MSG in processed foods) originally printed in Vegetarian Times, September 01, 1998 AccessMyLibrary record. "Want full ... Schwarcz, Joe (18 November 2009). "An injection of H1N1 reason". National Post. A game of hide and seek. ( ...
This process can only be used for single materials, so is not suitable for alloys. "Plastic Injection Molding - Custom Molded ... The process uses a mixture of metal powders and polymer binders - also known as "feedstock" - which are then injection-moulded ... The initial process does not achieve the required strength so parts must go through a secondary process which involves fusing ... Both of these processes are used in the following industries: Environmental Marine Oil and gas Housing Construction Food ...
Injection in-mold inoculation bowl melt». Patent RF № 2007267, B № 3, 15.02.94; U.Kudriavsky, V.Grachev, M.Zilberman and others ... Hardware and processing facility for disposal of highly toxic halogenated organic compounds». Patent RF № 45853, B. № 15, 27.05 ... V. Grachev made a great contribution to the theory of melting processes of casting alloys: he carried out a systematic analysis ... This resulted in the theoretical justification of the implementation of the cupola process with natural gas instead of coke. ...
... and then in a prolonged post-cure process. It can also be injection molded. Silicone rubber may be cured by a platinum- ... The curing process leaves behind byproducts, which can be an issue in food contact and medical applications. However, these ... For the platinum-catalyzed cure system, the curing process can be accelerated by adding heat or pressure. In a platinum-based ... Injection molding of liquid silicone rubber Forensic engineering Forensic polymer engineering Medical grade silicone RTV ...
"Rapid Injection Molder's Automated Process Creates Strategic Advantages for Clients". Design-2-Part Magazine. Retrieved 30 ... Injection molding is used for on-demand prototyping, bridge tooling, and low-volume production of up to 10,000+ parts. More ... Injection Molding: New Twists for a Mainstream Technology Forbes: "How Proto Labs Is Building The Factory Of The Future" ... Milling and turning processes are used to machine engineering-grade plastic and metal parts for prototyping and production. ...
"Microcellular Foam Injection Molding Process" (PDF). Retrieved 2016-02-17. http://www.trexel.com/en/ "Injection Molding Process ... The foam injection process itself introduces surface defects such as swirl marks, streaking, and blistering, which also ... Injection molding and blow molding differ in regards to the type of product in need of being manufactured. Injection molding, ... This process removed the "pack and hold phase" that allowed for imperfections within a mold, creating a finished product with ...
Dependency injection may be less supported. In the above UML class diagram, the Director class doesn't create and assemble the ... It removes what could be a complex building process from being the responsibility of the user of the object that is built. It ... A class (the same construction process) can delegate to different Builder objects to create different representations of a ... The Builder design pattern solves problems like: How can a class (the same construction process) create different ...
Modern manufacturing processes allow for diverse styles of nameplate design. Nameplates can be two- or three-dimensional; made ... of various metals (aluminum, zinc), stainless steel or brass, man-made materials (e.g. Mylar or Vinyls) or injection-molded ... For plastic and wooden nameplates, the names are etched into the material through a number of processes, including mechanical ... A graphic overlay is a screen or digitally printed product incorporating processes such as embossing, selective texturing and ...
Processes included injection molding, painting and electroplating. Initially the plant's primary customer was Ford Motor ... the episode followed the injection molding and chrome plating process of a Ford F-150 grille, one of the company's flagship ... The 46,000-square-foot (4,300 m2) facility houses a chrome plating line and four injection molding presses ranging from 165 to ... The company also announced its investment in a new 175,000-square-foot (16,300 m2) plastic injection molding and chrome plating ...
Hard tools for injection molding are going to be subjected to a lot of stress and heat during the injection process. They will ... Cast Urethanes are similar to injection molding. During the process of injection molding, a hard tool is created. The hard tool ... Master patterns for cast urethanes can be created with CNC machining (which is a common process for injection molding) but cast ... Plastic cups, dishware, and toys are most commonly made using the process of injection molding because they are common consumer ...
Process. 19 (2): 195-210. doi:10.1002/ppp.620.. *^ Wiltse, Brendan. "A Look Under The Ice: Winter Lake Ecology". Ausable River ... Water for injection is on the World Health Organization's list of essential medicines.[106] ... or to wash products or process equipment. Processes such as mining, chemical pulping, pulp bleaching, paper manufacturing, ... Ecological processes with hydrology are in focus of ecohydrology. The collective mass of water found on, under, and over the ...
Injection drug use may lead to primary bacteremia. In the hospital setting, use of blood vessel catheters contaminated with ... For this reason, blood cultures must be drawn with great attention to sterile process. The presence of certain bacteria in the ... Causes of bacteremia can additionally be divided into healthcare-associated (acquired during the process of receiving care in a ... Bacteremia is defined as either a primary or secondary process. In primary bacteremia, bacteria have been directly introduced ...
Approval Process, and Current Challenges". USPharmacist.com. Retrieved 10 December 2011. "Closamectin Pour on and Injection - ... company in the world which is licensed by the United States Food and Drugs Administration to manufacture sterile injections for ...
... while direct push injection techniques are generally quicker and less expensive. Injection wells for ozone are typically ... The overall end result of the process can be described by the following reaction: H 2O 2 + contaminant → H 2O + CO 2 + O 2 ... Injection probes are used in areas where there is very low permeability. A small diameter probe (2 to 4 cm in diameter) is ... An ozone injection grid was used that consisted of 116 stainless steel wells. After 16 months of ozone treatment, there was a ...
This process is used to break down an APM into small enough pieces to be processed through an incineration destruction method. ... There are two distinct technologies; 1) "entrainment" or 2) "direct injection". Research has now proven that the direct ... Pre-processed by a crusher. Used to process general chemical waste and explosive in solution. A typical production rate of ... The evolving gases are then processed by an integral pollution control system. Limited pre-processing is required and a wide ...
The models are made by the injection moulding process. The museum is included in the attractions covered by the Pune Municipal ...
Larger resin models, like buildings and vehicles, are sometimes gravity cast, which is a slower process. To gravity cast, a ... Polyethylene and polystyrene figures are made by injection moulding. A machine heats plastic and injects it under high pressure ... This is an expensive process; it is only cost effective when manufacturing large amounts of figures, since the quantity renders ... There are two basic methods of manufacturing figures: centrifugal/gravity casting and plastic injection casting. Most metal and ...
Injection devices are available to optimize the injection process. Side effects are often onerous enough that many patients ... To help prevent injection-site reactions, patients are advised to rotate injection sites and use an aseptic injection technique ... Also over time, a visible dent at the injection site due to the local destruction of fat tissue, known as lipoatrophy, may ... Interferon beta-1a is available only in injectable forms, and can cause skin reactions at the injection site that may include ...
They can also be made by injection molding plastic. Each process has its benefits and drawbacks such as cost and durability. ...
In this process, gaseous ethane briefly heated to 750-950 °C in a thermal cracker. The cracker is a large box with many gas ... Flare-The gas flare has continuous flame generation and steam injection to improve combustion. Control Room. This is a ... The major chemical process in this plant is dealkylation which is really the opposite of that occurring in the Aklylation plant ... There are 7 units in this plant The two main raw materials in this process are benzene and propylene. Benzene is a liquid that ...
It has 7 production and 2 water injection wells. Current production at Ula field is 10,000 bbl/d. The existing gas process ... from Ula will be pumped to facilities at Ula for processing. Norway portal Energy portal Norpipe North Sea oil Economy of ...
... may lead to a false understanding of the body and of the process of science.[169][178] Steven Novella, a ... Fabunan Antiviral Injection. *Facilitated communication. *Feldenkrais Method. *Functional medicine. *Hair analysis. *Herbal ...
Get guidance from medical experts to select lumbar epidural steroid injection specialist in Navi Mumbai from trusted hospitals ... Find the best lumbar epidural steroid injection doctors in Navi Mumbai. ... assistance company that gives guidance to a patient from the first consultation through the entire hospitalization process. A ... Best doctors for lumbar-epidural-steroid-injection in Navi Mumbai List of best Lumbar Epidural Steroid Injection Doctors from ...
Featured image for Uncovering cross-process injection with Windows Defender ATP March 8, 2017 Uncovering cross-process ... Attackers use methods that allow exploits to stay resident within an exploited process or migrate to a long-lived process ... injection with Windows Defender ATP Windows Defender Advanced Threat Protection (Windows Defender ATP) is a post-breach ...
Automotive injection molding is currently faced with tougher demands for low costs, higher quality and minimal inventory. The ... Productivity in the Injection Molding Process 830401. Automotive injection molding is currently faced with tougher demands for ... Citation: Gardner, A., "Productivity in the Injection Molding Process," SAE Technical Paper 830401, 1983, https://doi.org/ ...
... is a multi-component process, similar to the sandwich technique. By injecting inert gas into the molten plastic, hollow spaces ... Gas Injection Technique - Part Design and Process Capability 2001-01-3427. The gas injection technique (GIT) is a multi- ... Citation: Heim, H., "Gas Injection Technique - Part Design and Process Capability," SAE Technical Paper 2001-01-3427, 2001, ... In order to reach the desired gas flow, it must be stated that the position of melt and gas injection is of particular ...
Atlas eDiscovery Process Management has addressed vulnerablility due to SQL injection, where a remote attacker could send ... Atlas eDiscovery Process Management has addressed vulnerablility due to SQL injection, where a remote attacker could send ... DESCRIPTION: IBM Atlas eDiscovery Process Management is vulnerable to SQL injection. A remote attacker could send specially- ... Atlas eDiscovery Process Management. 6.0.3 - 6.0.3.5. Use Atlas eDiscovery Process Management version 6.0.3 Fix Pack 6. ...
looking add experienced plastic injection molding process technicians our team macedonia, . this excellent opportunity join ...
Botched execution in Oklahoma raises questions about lethal injection process. Apr 30, 2014 8:22 PM EST. ... Most lethal injections take place, if they are done correctly, within about four to five minutes. You are not going to have the ... do is what the United Kingdom did in the 1950s and have a commission of experts really go over how our lethal injection process ... Roy Englert, does this change the assumption by those who argue that lethal injection is a - can be a humane way to carry out ...
A flow injection nonaqueous solvent neutralization titration process and system is provided. The predetermined quantity of a ... A flow injection nonaqueous solvent neutralization titration process and system is provided. The predetermined quantity of a ... Furthermore, in a flow injection nonaqueous solvent neutralization titration process, the sample is mixed with the titrant to ... A first embodiment of a flow injection nonaqueous solvent neutralization titration process according to the present invention ...
... accurate measurement and documentation of cavity pressure for quality assurance in plastic injection molding. ... Cavity pressure measurement in injection molding Injection molding - process control Composite - process control ... Home/Solutions/Industrial Process Control/Cavity pressure measurement in injection molding/Injection molding - process control ... Injection Molding with No Compromises. Cavity Pressure Systems from Kistler. In plastic injection molding, accurate cavity ...
Detecting the injection process. Our BIW inductive positioning system ensures that your molds are quickly filled. Because the ... You can exactly calibrate the injection profile, for example, to produce high-quality, thin-wall parts. ... high sampling frequency and repeat accuracy measure the travel of the injection axis precisely and reliably. ...
D-LFT injection process is catching on.(Keeping Up With Composites) by Plastics Technology; Business Chemicals, plastics and ... process+is+catching+on.-a0112586087. *APA style: D-LFT injection process is catching on.. (n.d.) >The Free Library. (2014). ... This 7.5-lb part is the third commercial application of the IMC (injection molding-compounding) process of Krauss-Maffei (U.S. ... As compared with conventional injection molding of long-fiber pellets, this process saves one heat history and is said to ...
... the injection molding process represents an efficient manufacturing process of plastics, also allowing for high design ... Calculation concept shortens the design process of injection molded parts. 12.03.2019 ... the process developed by researchers at Fraunhofer LBF already takes the fiber orientation of short-fiber-reinforced injection ... This means that process parameters and tool geometries must be known and real moldings must be available. Consequently, this ...
Vetter Strikes out on New Pathways to Further Develop the Injection Process - read this article along with other careers ... Vetter Strikes out on New Pathways to Further Develop the Injection Process. Published: Jun 08, 2018 ... comfort aspects of the injection process for users as well as enhancements to our service offering based around the injection ... including professional caregivers and patients in an effort to create more purposeful injection processes. The campaign will ...
M. D. Luque de Castro, "Flow Injection Analysis: a new tool to automate extraction processes," Journal of Automatic Chemistry, ... Flow Injection Analysis: a new tool to automate extraction processes. M. D. Luque de Castro ...
Steps for crack injection including installing injection ports, sealing the surface, injecting the crack, and removing the ... Basic steps in the injection pocess Installing injection ports, sealing, epoxy vs. polyurethane, injection and port removal. ... How crack injection works A cost effective permanent fix for basement leaks. Low-Pressure Crack Injection (Basement Walls and ... The injection ports can then be removed by striking them with a trowel or hammer. If appearance is an issue, the epoxy surface ...
... thermoforming of continuous fiber preforms or blanks with injection molding or gas injection technology in a sequential process ... in a continuous process, thermoplastic injection-molded parts with thermoformed parts made from continuously fiber-reinforced ... Jacob Plastics Group had video screens at its stand to show off its "innovative and integrative" processes for large-scale ... Recycled fibers, in-situ polymerized PA12 and steel inserts combined in one-shot process to cut weight 40 percent at ...
... and new manufacturing including training across all shifts with respect to the injection molding and automation processes. ... Responsible for supporting and helping to establish process control and capability on all facets of existing ... Job Title: Process Engineer for Injection Molding. Department: Production Integration Team. Reports To: Director of ... and new manufacturing including training across all shifts with respect to the injection molding and automation processes. ...
This study explores the molding processes by using the Multi-component-injection molding (MCM) method, in which monolithic ... This study explores the molding processes by using the Multi-component-injection molding (MCM) method, in which monolithic ... A Study on Release Property through Self Coating in LSR Injection Process () ... A Study on Release Property through Self Coating in LSR Injection Process. Advances in Materials Physics and Chemistry, 5, 229- ...
... say the new process could open the door to injection-molded niobium parts ranging from rocket nozzles, to wires, to human bone ... Penn State researchers have developed the first powder injection molding process for pure niobium, a biocompatible material ... First powder injection molding process for pure niobium. Penn State researchers have developed the first powder injection ... The feedstock is then processed in a standard injection-molding machine. The resulting part is placed in a solvent that ...
... makes it possible to set the production start during injection moulding precisely preventing unnecessary ma... ... Weekly Timer registers changes automatically, responds and optimises the start of production of the injection moulding process ... Weekly Timer, the new function from KraussMaffei, makes it possible to set the production start during injection moulding ... The Weekly Timer detects changes to the process and reconfigures the times immediately and continuously. Thanks to this ...
We describe construction of the semi-analytical solutions, a process which differs in some ways from related displacements for ... calculations are presented for enhanced condensate recovery by gas injection. The semi-analytical approach allows investigation ... and also allows fast screening of optimal injection gas compositions. ... prediction of the formation of a mobile condensate bank at the displacement front in near-miscible gas cycling/injection ...
Injection molding is used to produce many car parts, including composite energy absorbers for bumpers. This part offers many ... Injection-Molded Composite Energy Absorbers Proven Worthy. Injection molding is a process used to make composite parts for a ... These energy absorbers have risen to such heights thanks to the composite process known as injection molding. This process ... Process Types. Closed Molding Light Resin Transfer Molding Reusable Bag Molding Vacuum Infusion Process ...
... centipoise at the injection temperature of the molding process. Since the process utilizes a mold which is externally heated, ... injection molding process using an externally heated mold. This molding process is ideally suited for production of limited ... centipoise at the injection temperature of the molding process. Since the process utilizes a mold which is externally heated, ... injection molding process using an externally heated mold. This molding process is ideally suited for production of limited ...
"Lethal Injection Secrecy and Eighth Amendment Due Process". The title of this post is the title of this timely new article by ... "Lethal Injection Secrecy and Eighth Amendment Due Process":. Comments. Not only is an execution extremely premeditated, ... This Article argues that the Eighth Amendment includes an implicit due process right to know such information about the states ... Indeed, judicial recognition of this due process right would not only protect Eighth Amendment values but would also encourage ...
Hijaxx - double hijacking: A new process injection method.... in Source Codes Started by Mist, 14 Feb 2017 Process injection ...
  • We explore some of the questions raised by this incident about the types of drugs used in lethal injections and whether states can carry them out while keeping with the constitutional requirement that they not be cruel and unusual. (pbs.org)
  • OULU, FINLAND/PARIS, FRANCE (3 January 2018) TactoTek®, the leader in Injection Molded Structural Electronics (IMSE) solutions announced that it is collaborating with Dassault Systèmes to enable users of the 3DEXPERIENCE platform to digitally experiment with TactoTek IMSE parts. (3ds.com)
  • The researchers, who are based in the University's Center for Innovative Sintered Products, say the new process could open the door to injection-molded niobium parts ranging from rocket nozzles, to wires, to human bone replacements, to orthodontic braces. (phys.org)
  • Once installed, the nozzles worked perfectly and the customer's process was back online in very little time. (bete.com)
  • 4. The liquid phase injection molding process of claim 1 or 2 wherein said carrier and binder component includes from 0.5 to 5 weight percent of a hydrocarbon mineral oil selected from the group consisting of liquid aliphatic hydrocarbonresins, mineral oil, hydrogenated aromatic resins and terpenes, paraffinic oils, and mixtures thereof. (patentgenius.com)
  • As moisture content in this and other hygroscopic resins varies, so will your viscosity and process. (ptonline.com)
  • You have less than 30 minutes in a normal processing environment to use most dried resins before they will pick up enough moisture to necessitate re-drying. (ptonline.com)
  • Farce 2016 Electoral Process: Lethal injection into Somalia's Statehood * Mareeg.com somalia, World News and Opinion. (mareeg.com)
  • Thus, lawful, credible free, fair, and transparent "selection and election process" which promotes a national political change in August 2016 is the stepping stone for democratic central government. (mareeg.com)
  • The no extension declaration for the term of office for the president and members of parliament of the federal government reiterated in the UN Security Council Resolution S/Res/2275 (2016) of 24th March 2016 will remain meaningless and deceptive if it is not responded with a legitimate democratic plan of selection/election process that withstands the test of the guiding principles for competitive, free, and fair selection/election process. (mareeg.com)
  • In order to reach the desired gas flow, it must be stated that the position of melt and gas injection is of particular importance. (sae.org)
  • The dispersion is realised during the continuous casting process by injecting suitable developed powders into the melt stream. (europa.eu)
  • The project and will take into account the whole manufacturing cycle (casting, hot rolling, annealing, cold rolling and annealing) even though the heart of the innovation concerns the injection of the ceramic powder into the melt stream during the casting process. (europa.eu)
  • Flow properties between PS and PC ABS, the liquidity and the injection temperature and pressure have a relationship, the influence of injection pressure slightly larger, thus forming often using higher injection pressure to reduce the melt viscosity, improve the filling performance. (felixprinters.com)
  • Parts fabricated via liquid silicone rubber injection molding are fire retardant and will not melt. (wikipedia.org)
  • To have the best performance and quality of your products, monitoring powders must be a part of your manufacturing process. (dksh.com)
  • DMLS involves the sintering of metallic powders in a layer-by-layer process with a high power laser. (scielo.org.za)
  • Screening of three light-oil reservoirs for application of air injection process by accelerating rate calorimetric and TG/PDSC tests," Journal of Canadian Petroleum Technology , vol. 41, no. 3, pp. 50-60, 2002. (hindawi.com)
  • A flow injection nonaqueous solvent neutralization titration process and system is provided. (freepatentsonline.com)
  • M. D. Luque de Castro, "Flow Injection Analysis: a new tool to automate extraction processes," Journal of Automatic Chemistry , vol. 8, no. 2, pp. 56-62, 1986. (hindawi.com)
  • We have developed an automatic As analyzer (Flow Injection Analyzer (FIA)) in the smelting process drainage. (go.jp)
  • Oil and gas processing, water/wastewater treatment and other industries that utilize chemical injection or additive monitoring in their product processing and operations will find the FLT93 Flow Switch Series from Fluid Components International (FCI) provides a highly reliable and rugged solution for verifying chemicals or additives are being injected and ensuring injection pumps and feeders continue to operate. (chemicalonline.com)
  • For monitoring chemical and other additive injection flow in small line sizes, the model FLT93L is an ultra-sensitive, inline-type flow switch that can detect liquid flow rates as low as 0.015 cc/sec and gas flow rates down to 0.6 cc/sec. (chemicalonline.com)
  • The FLT93 flow switches feature a universal 24Vdc/85V-265Vac power supply, temperature service up to 850°F [454°C] and a broad selection of process connections including compression fittings, flanges, packing glands. (chemicalonline.com)
  • An extensive selection of flow element materials, process connections and enclosures are available to ensure compatibility and easiest installation in your process. (chemicalonline.com)
  • Therefore, coupling thermal processes with fluid flow should be considered in order to correctly capture plume migration and trapping within the reservoir. (uib.no)
  • The flow diagram in Fig. 2 shows the sequence of processing steps. (pim-international.com)
  • I want to learn how to make the pre-processing file for analysis flow in ANSA. (cfd-online.com)
  • An automated flow injection potentiometric (FIP) system with electronic tongue detection (ET) is used for the monitoring of biosorption processes of heavy metals on vegetable wastes. (upc.edu)
  • The real-time monitoring of both the Cu2+ and the cation exchanged and released (Ca2+) in the effluent solution is performed by using flow-injection potentiometric electronic tongue system. (upc.edu)
  • These methods may not adequately identify the clogging processes occurring at low flow rates. (ku.edu)
  • To examine clogging processes at low flow rates, laboratory columns packed with sand and gravel cores, taken from the Pleistocene Belleville formation during direct-push well installation at the Lower Republican River field site, were used for clogging experiments. (ku.edu)
  • Plasticizers , not only to Phthalic Acid Esters and Phthalic anhydride but a wide variety and kinds, are often added to a lot of engineering and modern polymers and general plastics to improve their process ability, improve their flow ability and injection molding characteristics and also to improve their elasticity or reduce brittleness in them. (blogspot.com)
  • Oil flow into the injection cylinder must be reduced. (blogspot.com)
  • You can exactly calibrate the injection profile, for example, to produce high-quality, thin-wall parts. (balluff.com)
  • The Fraunhofer Institute for Structural Durability and System Reliability LBF has developed a method to take into account the fiber orientation of short-fiber-reinforced injection molded parts, even at stages where there are still no components, such as prototypes. (innovations-report.com)
  • By contrast, the process developed by researchers at Fraunhofer LBF already takes the fiber orientation of short-fiber-reinforced injection molded parts into account at a stage where no actual components are yet available. (innovations-report.com)
  • Injection molding is a process used to make composite parts for a variety of industries. (compositesone.com)
  • This molding process is ideally suited for production of limited quantities of molded parts, as comparatively low cost molds can be used. (patentgenius.com)
  • Using the 3DEXPERIENCE platform as a foundation for IMSE-specific engineering processes, designers and engineers can digitally create, simulate and test the real-world behavior of innovative IMSE parts in a collaborative 3D environment, and benefit from TactoTek validated IMSE design know-how. (3ds.com)
  • And, for sanitary processes, the Model FLT93C provides 20Ra electro-polished 316L stainless steel wetted parts and tri-clamp sanitary flanges to meet the requirements in the food, beverage and pharmaceutical industries. (chemicalonline.com)
  • The subsequent binder removal process serves to obtain parts with an interconnected pore network without destroying the shape of the components. (pim-international.com)
  • At the end of the binder removal process there is often still some binder present in the parts holding the metal powder particles together, but the pore network allows the evaporation of the residual binder quickly in the initial phase of sintering, at the same time as sintering necks start to grow between the metallic particles. (pim-international.com)
  • 1. Develops and maintains the process standards in which all parts manufactured. (ziprecruiter.com)
  • Very complicated mould parts can be produced through an additive manufacturing (AM) process, such as direct metal laser sintering (DMLS), and inserted into the aluminium moulds. (scielo.org.za)
  • Glass and carbon fiber reinforcements in injection molded parts have been used for many decades in combination with thermoplastics. (fraunhofer.de)
  • The methodology has been tested on three different parts from the medical (plastic injection and MIM) and automotive sector (plastic injection). (manunet.net)
  • Let's take a look at the key steps that tool and process engineers take to ensure consistent and repeatable manufacturability of flawless molded parts. (kaysun.com)
  • Experienced injection molders use scientific molding and DOE as the foundation for a robust and optimized injection molding process that leads to the successful manufacture of critical-use plastic parts and components by introducing a series of progressive checks and balances. (kaysun.com)
  • The most efficient and robust process possible for manufacturing the complex injection molded plastic parts and products you need for complex applications from medical devices to automotive parts . (kaysun.com)
  • 3. Fanuc injection machines can produce parts from different weight with high quality. (ttnet.net)
  • Injection molding of liquid silicone rubber (LSR) is a process to produce pliable, durable parts in high volume. (wikipedia.org)
  • For practical reasons, injection molds are best classified according to both the major design features of the molds themselves and the molding-operational features of the molded parts. (blogspot.com)
  • The paste cures in about 20 to 45 minutes to provide a surface seal with excellent bond characteristics that holds up under injection pressures. (concretenetwork.com)
  • In addition, we explore CO2 thermodynamic models for reliable prediction of density under different injection pressures, temperatures and composition. (uib.no)
  • The initiative will apply 'Design Thinking', a user-centered innovation method that involves direct communication with actual users of injection systems, including professional caregivers and patients in an effort to create more purposeful injection processes. (biospace.com)
  • This study explores the molding processes by using the Multi-component-injection molding (MCM) method, in which monolithic products are molded by attaching mixed liquid-silicone-rubbers (LSRs) to polybutylene terephthalate (PBT) that has the characteristic of self-binding while burning due to Pt catalysts. (scirp.org)
  • This Article argues that the Eighth Amendment includes an implicit due process right to know such information about the state's planned method of execution. (typepad.com)
  • Hijaxx - double hijacking: A new process injection method. (rohitab.com)
  • They also use this method to compare the atomized metal powder manufactured via different processes and select the most suitable powder. (dksh.com)
  • In the case of nylon, for example, if you are processing 30% glass-filled compound with a moisture content of 0.17%, (established with a moisture-specific method-weight loss is not acceptable), you may feel you are ready to process. (ptonline.com)
  • A method and apparatus are provided for adding controlled and accurate quantities of differing oils, to a polymer processing mixer without substantially contaminating one oil with another. (patentgenius.com)
  • We used Raman spectroscopic imaging method to monitor the multiphase reactive transport processes of co-injection of SO 2 together with CO 2 in optical cell and micro-model at conditions relevant to carbon capture and storage (CCS). (confex.com)
  • TLS callback injection is a method of executing arbitrary code in the address space of a separate live process. (mitre.org)
  • When working with hot preform method, the injection velocity will also make a significant difference to the material distribution in the finished container. (blogspot.com)
  • This technique has in the past been demonstrated to be effective against a method of guarding processes against DLL injection. (wikipedia.org)
  • A team of engineers specially trained in advanced methodologies such as Design for Manufacturability (DfM) is assembled to identify and possibly improve upon solutions to meet the particular project requirements - including the selection of materials for the final complex injection molded part and the tool. (kaysun.com)
  • Just as importantly, judicial recognition would also discourage secretive governmental practices more generally, thereby promoting openness and fair process as important democratic values. (typepad.com)
  • Generally speaking, there are few steps to preparing for PRP injections. (healthline.com)
  • Due to the thermosetting nature of the material, liquid silicone injection molding requires special treatment, such as intensive distributive mixing, while maintaining the material at a low temperature before it is pushed into the heated cavity and vulcanized . (wikipedia.org)
  • Glass-filled components were also evaluated in terms of glass fibre length and fibre distribution (post-injection). (sun.ac.za)
  • Fibre length and distributions obtained by polymer burn-off experiments served to help explain differences in properties of glass-filled products produced by the two processes. (sun.ac.za)
  • Execution via TLS callback injection may also evade detection from security products since the execution is masked under a legitimate process. (mitre.org)
  • The injection molding quality control system at Osborne Industries guarantees the RTM or RIM products we manufacture and deliver to our customers are of the highest quality and meet or exceed their intended expectations in the field. (osborneindustries.com)
  • Keep in mind, however, that the type of epoxy or polyurethane used and the time required for injection will vary with each job depending on the crack width, wall thickness, and other conditions. (concretenetwork.com)
  • Recycled fibers, in-situ polymerized PA12 and steel inserts combined in one-shot process to cut weight 40 percent at competitive cost, cycle time and safety. (compositesworld.com)
  • Air injection potential in Australian light oil reservoirs," in Proceedings of the SPE Asia Pacific Oil & Gas Conference and Exhibition , paper 101099, pp. 637-653, Adelaide, Australia, September 2006. (hindawi.com)