Predominant cortical dysfunction in Guadeloupean parkinsonism. (1/21)
(+info)Autonomic ganglia, acetylcholine receptor antibodies, and autoimmune ganglionopathy. (2/21)
(+info)Impaired baroreceptor reflex sensitivity in acute stroke is associated with insular involvement, but not with carotid atherosclerosis. (3/21)
(+info)Dysautonomia rating scales in Parkinson's disease: sialorrhea, dysphagia, and constipation--critique and recommendations by movement disorders task force on rating scales for Parkinson's disease. (4/21)
(+info)Ganglionic acetylcholine receptor autoantibody: oncological, neurological, and serological accompaniments. (5/21)
(+info)Peripherin-IgG association with neurologic and endocrine autoimmunity. (6/21)
(+info)A molecular sensor for the baroreceptor reflex? (7/21)
(+info)Dysautonomia due to reduced cholinergic neurotransmission causes cardiac remodeling and heart failure. (8/21)
(+info)'Primary Dysautonomias' are clinical disorders directly caused by genetically determined or inherited dysfunctions in the autonomic nervous system, which controls involuntary bodily functions such as heart rate, blood pressure, digestion, and body temperature.
Primary dysautonomias, also known as primary autonomic disorders or idiopathic dysautonomia, refer to a group of conditions that affect the autonomic nervous system (ANS) without an identifiable underlying cause. The ANS is responsible for regulating many automatic bodily functions such as heart rate, blood pressure, digestion, and body temperature.
In primary dysautonomias, the ANS fails to function properly, leading to a variety of symptoms that can affect different organ systems. These symptoms may include orthostatic intolerance (lightheadedness or fainting upon standing), irregular heart rate, excessive sweating, heat or cold intolerance, difficulty with digestion, and pupillary abnormalities.
Examples of primary dysautonomias include pure autonomic failure, multiple system atrophy, and familial dysautonomia. These conditions are typically progressive, meaning that symptoms tend to worsen over time. Treatment for primary dysautonomias is focused on managing symptoms and improving quality of life.
Primary autonomic failure
... (also called primary dysautonomia) refers to a category of dysautonomias - conditions in which the ... In primary dysautonomias, the autonomic dysfunction occurs as a primary condition (as opposed to resulting from another disease ... Such "primary" dysautonomias are distinguished from secondary dysautonomias, where the dysfunction of the autonomic nervous ... Many scientists also categorize Parkinson disease and familial dysautonomia as "primary". Noggle, Chad A.; Dean, Raymond S.; ...
Dysautonomia
... primary dysautonomia) or it may occur due to injury of the autonomic nervous system from an acquired disorder (secondary ... The prognosis of dysautonomia depends on several factors; individuals with chronic, progressive, generalized dysautonomia in ... Scholia has a profile for Dysautonomia (Dysautonomia). Brading A (1999). The autonomic nervous system and its effectors. Oxford ... The primary symptoms in individuals with dysautonomia include: Anhydrosis or hyperhidrosis Anxiety[better source needed] Blurry ...
Pure autonomic failure
... now grouped as primary autonomic disorders (also called primary dysautonomia), including Pure Autonomic Failure, Multiple ... Pure autonomic failure (PAF) is a form of dysautonomia that first occurs in middle age or later in life; diagnosed more often ... The primary differentiating characteristic of Pure autonomic failure is decreased circulation and synthesis of norepinephrine, ...
Orthostatic syncope
Neurally mediated causes include conditions that cause either primary or secondary failure of the autonomic system: Peripheral ... Acute dysautonomia (seen in a variant of Guillain-Barré syndrome) Toxin, drug or infection-induced neuropathy Non-neurally ... a definitive diagnosis may require a complete autonomic workup and coordination of care between the primary care provider, ...
Chromosome 9
Ehlers-Danlos syndrome familial dysautonomia Friedreich ataxia galactosemia Gorlin syndrome or nevoid basal cell carcinoma ... nonsyndromic deafness OCD polycythemia vera porphyria primary hyperoxaluria Tangier's disease tetrasomy 9p thrombotic ...
Hyperhidrosis
The cause of primary hyperhidrosis is unknown. Anxiety or excitement can exacerbate the condition. A common complaint of people ... dysreflexia Orthostatic hypotension Posttraumatic syringomyelia Associated with peripheral neuropathies Familial dysautonomia ( ... This use has been approved by the U.S. Food and Drug Administration (FDA). The duration of the beneficial effect in primary ... Primary or focal hyperhidrosis may be further divided by the area affected, for instance, palmoplantar hyperhidrosis ( ...
Neurological disorder
... the primary type of dysfunction involved, or the primary type of cause. The broadest division is between central nervous system ... system disorders Cranial nerve disorder such as Trigeminal neuralgia Autonomic nervous system disorders such as dysautonomia, ... Neurological disorders can be categorized according to the primary location affected, ...
Long COVID
Some people with long COVID experience dysautonomia, a malfunction of the central nervous system. People with dysautonomia may ... Greenhalgh T, Sivan M, Delaney B, Evans R, Milne R (September 2022). "Long covid-an update for primary care". BMJ. 378: e072117 ... Dysautonomia and postural orthostatic tachycardia syndrome (POTS) are also potential shared aspects of long COVID and ME/CFS. ... If people meet the diagnostic criteria for ME/CFS or for dysautonomia, it is possible that symptoms are lifelong. Estimates of ...
Electrochemical skin conductance
Assessment of dysautonomia is important for patient follow-up and assessment of sudomotor function can be helpful in daily ... The autonomic nervous system (ANS), of which sudomotor nerves are an integral part, is the primary extrinsic control mechanism ... ESC has clinical utility in the evaluation and follow-up of dysautonomia and small fiber peripheral neuropathy which may occur ... dysautonomia itself is an independent prognostic factor, and assessment of sweat disturbances is routine in the evaluation of ...
Parkinson's disease
non-primary source needed] Choi JG, Kim N, Ju IG, Eo H, Lim SM, Jang SE, et al. (January 2018). "Oral administration of Proteus ... January 2012). "Dysautonomia: perioperative implications". Anesthesiology. 116 (1): 205-215. doi:10.1097/ALN.0b013e31823db712. ... Assessment of sudomotor function through electrochemical skin conductance can be helpful in diagnosing dysautonomia. When PD ... closed). Strengthening exercises have shown improvements in strength and motor function for people with primary muscular ...
List of diseases (D)
Nonaka type Distal myopathy Distal primary acidosis, familial Distemper Distichiasis heart congenital anomalies Distomatosis ... thanatophoric Dwarfism thin bones multiple fractures Dyggve-Melchior-Clausen syndrome Dykes-Markes-Harper syndrome Dysautonomia ...
Mitral valve prolapse
It is the primary form of myxomatous degeneration of the valve. There are various types of MVP, broadly classified as classic ... Those with mitral valve prolapse and symptoms of dysautonomia (palpitations, chest pain) may benefit from beta-blockers (e.g., ... May 2019). "Primary cilia defects causing mitral valve prolapse". Science Translational Medicine. 11 (493). doi:10.1126/ ... May 2019). "Primary cilia defects causing mitral valve prolapse". Science Translational Medicine. 11 (493). doi:10.1126/ ...
Lorenz Studer
... the primary cell type affected in Parkinson's disease in vitro from dividing precursor cells. He successfully demonstrated that ... and using pluripotent stem cells as valuable tools for modeling human diseases such as Familial Dysautonomia, Hirschsprung's ...
Green ribbon
Dysautonomia, Interstitial Cystitis, Native American Reparation and Renal Cell Carcinoma Mixed ribbons: Anal Cancer (green & ... Primary Sclerosing Cholangitis, Pruned belly Syndrome, Von Hippel Lindau Gastroparesis Intellectual Disabilities Missing ...
Optic neuritis
The optic nerve comprises axons that emerge from the retina of the eye and carry visual information to the primary visual ... dysautonomia (i.e. autonomic nervous system dysfunction), and diabetes, or an injury to the eye. In neuromyelitis optica higher ...
Inappropriate sinus tachycardia
The mechanism and primary etiology of inappropriate sinus tachycardia has not been fully elucidated. An autoimmune mechanism ... Supraventricular tachycardia Sinus tachycardia Postural orthostatic tachycardia syndrome Dysautonomia Metabolic myopathies ...
Adrenergic storm
This enzyme is responsible for breaking down many compounds; basically, anything with a primary amine moiety is likely to be ... and dysautonomia present in the pre-coma stage of the disease. The behavioral symptoms are similar to those of an amphetamine, ...
Chiari malformation
"Dysautonomia News - Winter/Spring 2006". Dinet.org. Archived from the original on November 29, 2011. Retrieved November 4, 2011 ... Yu F, Jiang QJ, Sun XY, Zhang RW (June 2015). "A new case of complete primary cerebellar agenesis: clinical and imaging ... Maura Isles is diagnosed with the condition.[non-primary source needed] Rosanne Cash - U.S. singer-songwriter; daughter of ... Papilledema on fundoscopic exam due to Increased intracranial pressure Pupillary dilation Dysautonomia: tachycardia (rapid ...
Fibromyalgia
... non-primary source needed] increased pyruvate;[non-primary source needed] as well as reduced capillary density impairing oxygen ... An alternative hypothesis to nociplastic pain views fibromyalgia as a stress-related dysautonomia with neuropathic pain ... non-primary source needed] In patients with primary fibromyalgia, studies have found disruptions in energy metabolism within ... Primary fibromyalgia is idiopathic (cause unknown), whereas secondary fibromyalgia is in association with a known underlying ...
Orthostatic headache
Previously it was often misdiagnosed as different primary headache disorders such as migraine or tension headaches. Increasing ... Another cause of orthostatic headaches is postural orthostatic tachycardia syndrome (POTS), a form of dysautonomia, which is ...
Eating disorder
Rushing JM, Jones LE, Carney CP (October 2003). "Bulimia Nervosa: A Primary Care Review". Primary Care Companion to the Journal ... Dysautonomia can occur in conditions such as diabetes and alcoholism. Psychological disorders which may be confused with an ... Dysautonomia usually involves failure of sympathetic or parasympathetic components of the ANS system but may also include ... Ritchie, M Perdigao J,) Dysautonomia: a wide variety of autonomic nervous system (ANS) disorders may cause a wide variety of ...
Norepinephrine transporter
However, DAT, the primary way dopamine is transported out of the cell, can work to decrease dopamine concentration in the ... Orthostatic intolerance (OI) is a disorder of the autonomic nervous system (a subcategory of dysautonomia) characterized by the ... subsequently replaced tricyclics as the primary treatment option for depression because of their better tolerability and lower ...
List of diseases (M)
... primary autosomal recessive Microco Microcoria, congenital Microcornea correctopia macular hypoplasia Microcornea glaucoma ... Morse-Rawnsley-Sargent syndrome Motor neuron disease Motor neuro-ophthalmic disorders Motor neuropathy peripheral dysautonomia ...
Dementia with Lewy bodies
... and dysautonomia from the use of antipsychotics. Dysautonomia (autonomic dysfunction) occurs when Lewy pathology affects the ... They are most frequently due to primary neurodegenerative disease, resulting in the loss of dopaminergic nerve terminals along ... Thus, alpha-synuclein aggregation was established as the primary building block of the synucleinopathies. Between 1995 and 2005 ... Falls-caused by many factors including parkinsonism, dysautonomia, and frailness-increase morbidity and mortality. Failure to ...
Orthostatic hypotension
Primary orthostatic hypotension is also often referred to as neurogenic orthostatic hypotension. The drop in blood pressure may ... and other forms of dysautonomia. It is also associated with Ehlers-Danlos syndrome and anorexia nervosa. It is also present in ...
Ehlers-Danlos syndromes
"Ehlers-Danlos Syndrome". Underlying Causes of Dysautonomia. Dysautonomia International. 2012. Archived from the original on ... Group A disorders are those that affect primary collagen structure and processing. Group B disorders affect collagen folding ... Collagen primary structure and collagen processing: ADAMTS2, COL1A1, COL1A2, COL3A1, COL5A1, COL5A2 Collagen folding and ... Heart murmur Heart conduction abnormalities Hiatal hernia Gastroesophageal reflux Poor gastrointestinal motility Dysautonomia ...
List of neurological conditions and disorders
... spinal muscular atrophy type 2 Dizziness Down syndrome Dravet syndrome Duchenne muscular dystrophy Dysarthria Dysautonomia ... Posttraumatic stress disorder Postural hypotension Postural orthostatic tachycardia syndrome Prader-Willi syndrome Primary ...
PHOX2B
Mutations in human PHOX2B cause a rare disease of the visceral nervous system (dysautonomia): congenital central ... "Diagnostic Utility of PHOX2B in Primary and Treated Neuroblastoma and in Neuroblastoma Metastatic to the Bone Marrow". Archives ...
List of MeSH codes (C10)
... primary MeSH C10.228.140.546.399.750 - migraine disorders MeSH C10.228.140.546.399.750.250 - migraine with aura MeSH C10.228. ... dysautonomia, familial MeSH C10.574.500.497 - huntington disease MeSH C10.574.500.529 - lafora disease MeSH C10.574.500.536 - ... primary progressive aphasia MeSH C10.228.140.380.165 - creutzfeldt-jakob syndrome MeSH C10.228.140.380.230 - dementia, vascular ... primary progressive aphasia MeSH C10.597.606.150.500.800.100.166 - receptive aphasia MeSH C10.597.606.150.500.800.150 - ...
Lesch-Nyhan syndrome
Of these, only individuals with Lesch-Nyhan syndrome, de Lange syndrome, and familial dysautonomia recurrently display loss of ... non-primary source needed] However, some evidence suggests against a role for uric acid in the neuropathology of Lesch-Nyhan ... familial dysautonomia, choreoacanthocytosis, sensory neuropathy including hereditary sensory neuropathy type 1, and several ... syndrome: Hyperuricemia associated with classic primary gout, which is caused by low uric acid renal clearance rather than uric ...