Prevotella melaninogenica
Prevotella
Bacteria, Anaerobic
Prevotella intermedia
Porphyromonas
Prevotella ruminicola
Blastogenic response of human lymphocytes to oral bacterial antigens: comparison of individuals with periodontal disease to normal and edentulous subjects. (1/79)
Cell-mediated immunity in humans to antigens derived from oral plaque bacteria was investigated by using the lymphocyte blastogenesis assay. Subjects with varying severities of periodontal disease including normal, gingivitis, periodontitis, and edentulous were compared. Mononuclear leukocytes were separated from peripheral blood and cultured with antigens prepared by sonication of Actinomyces viscosus (AV), Actinomyces naeslundii (AN), Veillonella alcalescens (VA), Leptotrichia buccalis (LB), Bacteroides melaninogenicus (BM), and homologous dental plaque (DP). The lymphocyte response of subjects with gingivitis or periodontitis was significantly greater than that of normal subjects to antigens of AV, AN, and DP, but did not differ from the response of edentulous subjects. Periodontitis subjects were significantly more reactive than edentulous and normal subjects in response to VA, LB, and BM. These findings suggest that the tested gram-negative bacteria and the host response they evoke are associated with advanced periodontal destruction. (+info)Characterization of bacteroides melaninogenicus. (2/79)
Fifty-eight human isolates of Bacteroides melaninogenicus, 42 from a variety of clinical infections and the rest from normal flora, were studied for pigment production and ultraviolet light fluorescence and by forty biochemical and other tests, including end-product analysis by gas-liquid chromatography. In a number of instances, tests were repeated several times and the results were reproducible. Agar plate dilution susceptibility tests were also performed to 12 antimicrobial agents. These 58 strains could be reliably placed into three groups, corresponding to the three subspecies described, based on seven characteristics. These included acid production in peptone-yeast-glucose medium, production of n-butyric acid from peptone-yeast-glucose medium, esculin hydrolysis, starch hydrolysis, indole production, effect on milk, and lipase production. Production of hydrogen gas in peptone-yeast-fructose medium may be another distinguishing characteristic. In general there was not much difference in the susceptibility of the three groups to the various antimicrobial agents tested. Two strains had a minimal inhibitory concentration of penicillin G of 16 and 32 U/ml, respectively. Three strains did not produce a black pigment in spite of prolonged incubation on blood-containing media. (+info)Induction of oxidative DNA damage in anaerobes. (3/79)
We compared oxidative DNA damage in strictly anaerobic Prevotella melaninogenica, aerotolerant anaerobic Bacteroides fragilis, and facultative anaerobic Salmonella typhimurium after exposure to O2 or H2O2. Using HPLC with electrochemical detection, we measured 8-hydroxydeoxyguanosine (8OHdG) as a damage marker. O2 induced 8OHdG in P. melaninogenica but not in B. fragilis, which shows catalase activity, or in S. typhimurium. In P. melaninogenica, with catalase, O2 induced less 8OHdG; superoxide dismutase had no effect; with glucose and glucose oxidase, O2 induced more 8OHdG. H2O2 also markedly increased 8OHdG. O2 was suggested to induce 8OHdG through H2O2. O2 or H2O2 decreased survival only in P. melaninogenica. Highly sensitive to oxidative stress, P. melaninogenica could prove useful for investigating oxidative DNA damage. (+info)Evaluation of enrichment, storage, and age of blood agar medium in relation to its ability to support growth of anaerobic bacteria. (4/79)
By measuring the colony size of a variety of anaerobic bacteria isolated from clinical specimens, an evaluation was made of the benefits derived from the addition of several enrichments to blood agar medium commonly used for the growth of anaerobes. Similar methods were used to study the effects of various storage conditions and age of the medium. The results were compared with those obtained on freshly prepared and enriched blood agar plates as well as commercially available blood agar plates. Freshly prepared and enriched blood agar was found to give substantially larger colonies than could be grown on commercially obtained blood agar plates when both were inoculated and incubated under identical conditions. Storage of plating media under CO2 for periods of up to 72 h had only a minor effect on the growth of the anaerobic bacteria studied, but longer periods of storage under CO2 resulted in a less efficient plating medium. Nonenriched brain heart infusion (BHI) was found to be a better basal medium than Trypticase soy agar (TSA) medium. Colony size on fully enriched BHI blood agar plates was greater than nonenriched BHI greater than nonenriched TSA greater than commercially prepared nonenriched TSA plates. The data suggest that freshness of the plates may be as important as using rich media. (+info)Casamino acids enhance growth of Bacteroides melaninogenicus. (5/79)
Casamino Acids enhance the growth of Bacteroides melaninogenicus when added to various concentrations of Trypticase. Absence of a peptide, not amino acids, is responsible for the inability of Casamino Acids to support growth. (+info)Beta-Lactamase activity in strains of Bacteroides melaninogenicus and Bacteroides oralis. (6/79)
beta-Lactamase from strains of Bacteroides melaninogenicus and Bacteroides oralis hydrolyzed penicillin more rapidly than ampicillin or carbenicillin. Cephalothin and a chromogenic cephalosporin (87/312) were also hydrolyzed by the enzyme. Activity was found only in beta-lactam-resistant strains, but there was considerable variation in activity among strains having the same minimal inhibitory concentrations of antibiotic. beta-Lactamase activity was cell bound and appeared to be tightly associated with the cell envelope since detergents were required to elute this activity. (+info)Fermentation of L-aspartate by a saccharolytic strain of Bacteroides melaninogenicus. (7/79)
Resting cells of Bacteroides melaninogenicus fermented L-[14C]aspartate as a single substrate. The 14C-labeled products included succinate, acetate, CO2, oxaloacetate, formate, malate, glycine, alanine, and fumarate in the relative percentages 68, 15, 9.9, 2.7, 1.8, 1.0, 0.7, 0.5, and 0.06, respectively, based on the total counts per minute of the L-[14C]aspartate fermented. Ammonia was produced in high amounts, indicating that 96% of the L-aspartate fermented was deaminated. These data suggest that L-aspartate is mainly being reduced through a number of intermediate reactions involving enzymes of the tricarboxylic acid cycle to succinate. L-[14C]asparagine was also fermented by resting cells of B. melaninogenicus to form L-aspartate, which was subsequently, but less actively, fermented. (+info)Rapid screening of Veillonella by ultraviolet fluorescence. (8/79)
Among 51 strains of anaerobic gram-negative cocci belonging to the family Veillonellaceae, all strains of Veillonella (V. parvula and V. alcalescens) displayed red fluorescence under long-wave (366 nm) ultraviolet light, whereas no Acidaminococcus or Megasphaera demonstrated fluorescence. In contrast to Bacteroides melaninogenicus, growth of Veillonella does not require hemin and menadione, and flourescence is rapidly lost upon exposure to air. The fluorescent component of a strain of V. parvula examined could not be extracted in solution with water, ether, methanol, or chloroform, but was readily extracted with 0.4 N NaOH. Spectrophotofluorometrically, the fluorescence maximum of this extract was 660 nm with an excitation maximum of 300 nm, when measured at pH 7.2 and 25 C. Coupled with the Gram stain, ultraviolet fluorescence may be a useful tool for rapid screening of Veillonella and is particularly helpful for detection and, isolation of this organism from mixed culture. (+info)"Prevotella melaninogenica" is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found as part of the normal microbiota in the oral cavity, gastrointestinal tract, and urogenital tract. It is named for its ability to produce melanin pigment. This bacterium can sometimes be associated with various infections, including dental abscesses, periodontal disease, lung infections, and bloodstream infections, particularly in individuals with compromised immune systems."
Preventella is a genus of Gram-negative, anaerobic, rod-shaped bacteria that are commonly found in the human oral cavity, gastrointestinal tract, and urogenital tract. They are part of the normal microbiota but can also be associated with various infections, particularly in individuals with compromised immune systems or underlying medical conditions.
Prevotella species have been implicated in a variety of diseases, including periodontal disease, dental caries, respiratory tract infections, bacteremia, soft tissue infections, and joint infections. They can also be found in association with abscesses, wound infections, and other types of infections, particularly in the head and neck region.
Prevotella species are generally resistant to antibiotics commonly used to treat anaerobic infections, such as clindamycin and metronidazole, making them difficult to eradicate. Therefore, accurate identification and susceptibility testing of Prevotella isolates is important for the appropriate management of infections caused by these organisms.
Anaerobic bacteria are a type of bacteria that do not require oxygen to grow and survive. Instead, they can grow in environments that have little or no oxygen. Some anaerobic bacteria can even be harmed or killed by exposure to oxygen. These bacteria play important roles in many natural processes, such as decomposition and the breakdown of organic matter in the digestive system. However, some anaerobic bacteria can also cause disease in humans and animals, particularly when they infect areas of the body that are normally oxygen-rich. Examples of anaerobic bacterial infections include tetanus, gas gangrene, and dental abscesses.
Prevotella intermedia is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the oral cavity, upper respiratory tract, and gastrointestinal tract. It is a normal resident of the human microbiota but can also be an opportunistic pathogen, causing various types of infections such as periodontitis, endocarditis, and brain abscesses. P. intermedia has been associated with several diseases, including respiratory tract infections, bacteremia, and joint infections. It is often found in mixed infections with other anaerobic bacteria. Proper identification of this organism is important for the selection of appropriate antimicrobial therapy.
"Porphyromonas" is a genus of gram-negative, anaerobic bacteria that are commonly found in the human oral cavity and other areas of the body. One species, "Porphyromonas gingivalis," is a major contributor to chronic periodontitis, a severe form of gum disease. These bacteria are also associated with various systemic diseases, including atherosclerosis, rheumatoid arthritis, and aspiration pneumonia. The name "Porphyromonas" comes from the Greek words "porphyra," meaning purple, and "monas," meaning unit, referring to the bacteria's ability to produce porphyrins, which are pigments that can give a purple color to their colonies.
Bacteroidaceae is a family of gram-negative, anaerobic bacteria that are commonly found in the human gastrointestinal tract. Infections caused by Bacteroidaceae are relatively rare, but can occur in cases of severe trauma, surgery, or compromised immune systems. These infections may include bacteremia (bacteria in the blood), abscesses, and wound infections. Treatment typically involves the use of antibiotics that are effective against anaerobic bacteria. It is important to note that proper identification of the specific species causing the infection is necessary for appropriate treatment, as different species within Bacteroidaceae may have different susceptibilities to various antibiotics.
"Prevotella ruminicola" is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the oral cavity and gastrointestinal tract of humans and animals. It is one of the predominant species in the rumen of ruminants, where it plays a crucial role in the breakdown and fermentation of plant material. However, it can also be an opportunistic pathogen and has been associated with various infections, including periodontal disease, aspiration pneumonia, and bacteremia. Proper oral hygiene and healthcare practices are essential to prevent the overgrowth and potential infection caused by this bacterium.
"Prevotella nigrescens" is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the human oral cavity, intestinal tract, and female genital tract. It is a member of the normal microbiota of these areas but has been associated with various infections such as periodontitis, endodontic infections, aspiration pneumonia, and bacteremia. The bacterium can also be found in association with abscesses, wound infections, and other types of soft tissue infections. It is important to note that the presence of "Prevotella nigrescens" alone does not necessarily indicate infection, as it can also be present in the absence of disease. However, its identification in clinical specimens may warrant further investigation and appropriate treatment.
Prevotella melaninogenica
Campylobacter rectus
Bacteroides
Prevotella
Dental plaque
Prevotella bivia
Oral microbiology
Veillonella parvula
Diploderma splendidum
Clarithromycin
List of clinically important bacteria
List of MeSH codes (B03)
Prevotella melaninogenica - Wikipedia
Prevotella melaninogenica - WikEM
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Bacteroides9
- P. melaninogenica was originally described as Bacteroides melaninogenicus in 1921 by Wade Oliver and William Wherry at the University of Cincinnati as a new bacterium isolated from various sites of several different human patients. (wikipedia.org)
- In 1990, Haroun Shah and David Collins at the London Hospital Medical College reclassified several species of Bacteroides, including B. melanogenicus under a new genus called Prevotella. (wikipedia.org)
- Within this study, the pathogen-specific IgG levels formed against Porphyromonas gingivalis FDC 381, Prevotella melaninogenica ATCC 25845, Actinobacillus actinomycetemcomitans Y4, Bacteroides forsythus ATCC 43047, and Prevotella intermedia 25611 oral bacteria were researched from the blood serum samples of 30 RA patients and 20 healthy controls with the enzyme-linked immunosorbent assay (ELISA) method. (medscape.com)
- Porphyromonas gingivalis, Prevotella intermedia, Prevotella melaninogenica , and Bacteroides forsythus are gram-negative small basil quality obligate anaerobic bacteria and are held directly responsible for the formation of periodontitis (Periodontopathic bacteria). (medscape.com)
- [ 6 ] These bacteria were classified in the Bacteroides genus until 1988 and 1990, when they were reclassified to the Porphyromonas and Prevotella genera, respectively, in accordance with new classification strategies made by Shah and Collins. (medscape.com)
- In this study, we investigated the oral Bacteroides, Porphyromonas, and Prevotella bacteria antibodies usually found in periodontitis etiopathogenesis but from serum samples of RA patients. (medscape.com)
- including Bacteroides fragilis and Prevotella melaninogenica), Fusobacterium spp. (rxeli.com)
- [ 1 ] group and other anaerobic gram-negative bacilli (AGNB) that were previously included in the Bacteroides genus but are now included in the Prevotella and Porphyromonas genera. (medscape.com)
- Prevotella bivia and Prevotella disiens (previously called Bacteroides ) are important in obstetric and gynecologic infections. (medscape.com)
Streptococcus3
- Gram-positive bacteria such as Streptococcus salivaris, Prevotella melaninogenica, L. wadei, and Actinomyces spp. (bvsalud.org)
- Streptococcus was the most abundant genus in oral cavities while Prevotella and Fusobacterium were most abundant in diseased samples. (psu.edu)
- Using rigorous criteria and novel bioinformatics tools, we found that Granulicatella adiacens, Eubacterium yurii, Prevotella melaninogenica, Prevotella salivae, Streptococcus mitis, and Atopobium rimae were over-represented in diseased samples.Conclusions: We used a novel approach and high-throughput methodologies to characterize the microbiota associated normal and diseased oral sites in the same individuals. (psu.edu)
Intermedia2
- The IgG levels of P gingivalis, P intermedia, P melaninogenica, and B forsythus were found to be significantly higher in RA patients when compared with those of the controls. (medscape.com)
- The antibodies formed against P gingivalis, P intermedia, P melaninogenica, and B forsythus could be important to the etiopathogenesis of RA. (medscape.com)
Fusobacterium1
- Organisms in the Prevotella group and Fusobacterium species are part of the normal oral, vaginal, and large-bowel flora. (msdmanuals.com)
Primary human oral keratinocytes2
- SHAO Ruru,ZHENG Zhanglong,XU Pan,et al.The time series gene expression profiles of primary human oral keratinocytes stimulated by Prevotella melaninogenica[J].同济大学学报(医学版),2023,44(5):640-647. (cnjournals.cn)
- Objective To investigate the time trend of gene expression of primary human oral keratinocytes(pHOKs) stimulated with Prevotella melaninogenica(Pm), and to explore the potential mechanism of interaction between Pm and pHOKs. (cnjournals.cn)
Bacteria2
- P. melaninogenica are Gram-negative rod-shaped bacteria. (wikipedia.org)
- [ 5 ] A recent Brazilian study using 16S rRNA PCR and sequencing performed on cultivable bacteria from acute apical abscesses revealed the most common identified bacteria were Prevotella sp, Pseudoramibacter alactolyticus , Parvimonas micra , Dialister invisus , Filifactor alocis and Peptostreptococcus stomatis . (medscape.com)
Species2
- Prevotella melaninogenica is a species of bacterium in the normal microbiota of the upper respiratory tract. (wikipedia.org)
- Prevotella mizrahii is the correct name if this species is regarded as a separate species (i.e., if its nomenclatural type is not assigned to another species whose name is validly published, legitimate and not rejected and has priority) within a separate genus Prevotella . (dsmz.de)
Buccal mucosa1
- Previous studies of our group found that the composition ratio of Prevotella melaninogenica (Pm) on the buccal mucosa surface of OLP patients increased significantly. (nih.gov)
Genomes1
- Lineages with type strain genome sequencing projects registered in GOLD are shown in blue, published genomes and Prevotella melaninogenica released Genbank accession CP002122 in bold. (bioz.com)
Scopos1
- Reads equally close to P. melaninogenica, P. scopos, and P. sp. (homd.org)
Anaerobic1
- P. melaninogenica is an anaerobic, Gram-negative rod, named for its black colonies, and black pigment. (wikipedia.org)
Rectus1
- P. melaninogenica is associated with hypertension together with Campylobacter rectus and Veillonella parvula. (wikipedia.org)
Blood1
- P. melaninogenica grow well on blood agar, where they form circular dark-colored colonies that darken over one to two weeks. (wikipedia.org)