An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.
Method to determine the occurrence of OVULATION by direct or indirect means. Indirect methods examine the effects of PROGESTERONE on cervical mucus (CERVIX MUCUS), or basal body temperature. Direct ovulation detection, generally used in fertility treatment, involves analyses of circulating hormones in blood and ULTRASONOGRAPHY.
An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.
A metabolite of 17-ALPHA-HYDROXYPROGESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE.
A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.
The period from onset of one menstrual bleeding (MENSTRUATION) to the next in an ovulating woman or female primate. The menstrual cycle is regulated by endocrine interactions of the HYPOTHALAMUS; the PITUITARY GLAND; the ovaries; and the genital tract. The menstrual cycle is divided by OVULATION into two phases. Based on the endocrine status of the OVARY, there is a FOLLICULAR PHASE and a LUTEAL PHASE. Based on the response in the ENDOMETRIUM, the menstrual cycle is divided into a proliferative and a secretory phase.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
The discharge of an OVUM from a rupturing follicle in the OVARY.
The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)
The privacy of information and its protection against unauthorized disclosure.
Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.
Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.
The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.
Process that is gone through in order for a device to receive approval by a government regulatory agency. This includes any required preclinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance. It is not restricted to FDA.
Freedom of equipment from actual or potential hazards.
An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.
The act or practice of killing for reasons of mercy, i.e., in order to release a person or animal from incurable disease, intolerable suffering, or undignified death. (from Beauchamp and Walters, Contemporary Issues in Bioethics, 5th ed)
Active euthanasia of a patient at the patient's request and/or with the patient's consent.
Expendable and nonexpendable equipment, supplies, apparatus, and instruments that are used in diagnostic, surgical, therapeutic, scientific, and experimental procedures.
Men and women working in the provision of health services, whether as individual practitioners or employees of health institutions and programs, whether or not professionally trained, and whether or not subject to public regulation. (From A Discursive Dictionary of Health Care, 1976)
The study of the origin, nature, properties, and actions of drugs and their effects on living organisms.
Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.
Attitudes of personnel toward their patients, other professionals, toward the medical care system, etc.
Systems developed for collecting reports from government agencies, manufacturers, hospitals, physicians, and other sources on adverse drug reactions.
A genus of the family HYLOBATIDAE consisting of six species. The members of this genus inhabit rain forests in southeast Asia. They are arboreal and differ from other anthropoids in the great length of their arms and very slender bodies and limbs. Their major means of locomotion is by swinging from branch to branch by their arms. Hylobates means dweller in the trees. Some authors refer to Symphalangus and Nomascus as Hylobates. The six genera include: H. concolor (crested or black gibbon), H. hoolock (Hoolock gibbon), H. klossii (Kloss's gibbon; dwarf siamang), H. lar (common gibbon), H. pileatus (pileated gibbon), and H. syndactylus (siamang). H. lar is also known as H. agilis (lar gibbon), H. moloch (agile gibbon), and H. muelleri (silvery gibbon).
A family of the suborder HAPLORHINI comprising only one genus, HYLOBATES (also called Nomascus or Symphalangus).
Force exerted when using the index finger and the thumb. It is a test for determining maximum voluntary contraction force.
Condition wherein the force of gravity is greater than or is increased above that on the surface of the earth. This is expressed as being greater than 1 g.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Variations of menstruation which may be indicative of disease.
The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.
The period of the MENSTRUAL CYCLE representing follicular growth, increase in ovarian estrogen (ESTROGENS) production, and epithelial proliferation of the ENDOMETRIUM. Follicular phase begins with the onset of MENSTRUATION and ends with OVULATION.
The period before MENOPAUSE. In premenopausal women, the climacteric transition from full sexual maturity to cessation of ovarian cycle takes place between the age of late thirty and early fifty.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
A suspension of metallic gold particles.
Exclusive legal rights or privileges applied to inventions, plants, etc.
A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
A suspension of radioactive gold particles emitting negative beta particles and gamma irradiation. It was formerly used for liver scans and irradiation treatment of some metastatic malignancies.
Two-phase systems in which one is uniformly dispersed in another as particles small enough so they cannot be filtered or will not settle out. The dispersing or continuous phase or medium envelops the particles of the discontinuous phase. All three states of matter can form colloids among each other.
Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved death domains that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
Compounds that interact with PROGESTERONE RECEPTORS in target tissues to bring about the effects similar to those of PROGESTERONE. Primary actions of progestins, including natural and synthetic steroids, are on the UTERUS and the MAMMARY GLAND in preparation for and in maintenance of PREGNANCY.
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
A pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.
A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
The branch of medicine dealing with the fetus and infant during the perinatal period. The perinatal period begins with the twenty-eighth week of gestation and ends twenty-eight days after birth. (From Dorland, 27th ed)
Steroids that contain a ketone group at position 17.
A plant genus of the family FABACEAE. Some species were reclassified from CASSIA and Senna.
Metastatic lesion of the UMBILICUS associated with intra-abdominal neoplasms especially of the GASTROINTESTINAL TRACT or OVARY.
The division of a ZYGOTE into two parts, each of which is capable of further development.
The pit in the center of the ABDOMINAL WALL marking the point where the UMBILICAL CORD entered in the FETUS.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.

Caffeine consumption and menstrual function. (1/115)

The relation between caffeine intake and menstrual function was examined in 403 healthy premenopausal women who belonged to Kaiser Permanente Medical Care Program in 1990-1991. A telephone interview collected information about caffeinated beverage intake as well as other lifestyle, demographic, occupational, and environmental factors. Subjects collected daily urine samples and completed a daily diary for an average of five menstrual cycles. Metabolites of estrogen and progesterone were measured in the urine, each cycle was characterized as anovulatory or ovulatory, and a probable day of ovulation was selected when appropriate. Logistic regression and repeated measures analyses were performed on menstrual parameters. Women whose caffeine consumption was heavy (>300 mg of caffeine per day) had less than a third of the risk for long menses (> or =8 days) compared with women who did not consume caffeine (adjusted odds ratio = 0.30, 95% confidence interval 0.14-0.66). Those whose caffeine consumption was heavy also had a doubled risk for short cycle length (< or =24 days) (adjusted odds ratio = 2.00, 95% confidence interval 0.98-4.06); this association was also evident in those whose caffeine consumption was heavy who did not smoke (adjusted odds ratio = 2.11, 95% confidence interval 1.03-4.33). Caffeine intake was not strongly related to an increased risk for anovulation, short luteal phase (< or =10 days), long follicular phase (> or =24 days), long cycle (> or =36 days), or measures of within-woman cycle variability.  (+info)

Reproducibility and validity of radioimmunoassays for urinary hormones and metabolites in pre- and postmenopausal women. (2/115)

The reproducibility of RIAs of circulating sex hormones has been evaluated as part of recent epidemiological investigations, but none seem to have addressed the reproducibility or validity of RIAs for urinary hormones or their metabolites. As part of a case-control study of breast cancer in Asian-American women, 12-h overnight urine samples were obtained, and a methodological study was conducted to identify laboratories capable of assaying urinary hormones. For the reproducibility component of this study, two laboratories with extensive experience in hormone assays measured urinary estrone, estradiol, estriol, pregnanediol glucuronide, and estrone glucuronide using samples from 15 women (5 midfollicular, 5 midluteal, and 5 postmenopausal). Variance estimates from these measurements were used to calculate the laboratory variability (coefficient of variation) and to assess the magnitude of the biological variability among the women in relation to the total variability (intraclass correlation coefficient). For the validity component, urinary estrone, estradiol, and estriol levels were measured in the same samples by gas chromatography-mass spectroscopy in the laboratory of Dr. Herman Adlercreutz (University of Helsinki, Helsinki, Finland). We found that the degree of assay reproducibility differed between the laboratories, but that laboratory variability was usually low compared with the range of hormone values among women, particularly for the estrogens. Values for estrone and estradiol were well correlated among all of the laboratories. For estriol, the RIAs tended to overestimate levels compared with gas chromatography-mass spectroscopy. In one laboratory, assays for pregnanediol glucuronide and estrone glucuronide were consistently reproduced; in the other, the reproducibility of the RIA for pregnanediol glucuronide was problematic, and estrone glucuronide was not measured. Despite some limitations, urinary hormones and their metabolites can be reliably measured by current RIAs in large investigations attempting to link hormone level to disease risk and may be particularly advantageous for studies of postmenopausal women, where serum concentrations of estrone and estradiol are low and assay measurements are not as dependable.  (+info)

Mechanism for the development of ovarian cysts in patients with congenital lipoid adrenal hyperplasia. (3/115)

OBJECTIVE: Although ovarian cysts commonly occur in patients with congenital lipoid adrenal hyperplasia (CLAH), the mechanism of development remains to be determined. To clarify the pathogenesis of the ovarian cysts, endocrinological examinations were performed in patients with CLAH. METHODS: The subjects were three Japanese CLAH patients. Basal body temperature, serum and urinary gonadotropin levels, serum and/or urinary ovarian hormones and mutations of the steroidogenic acute regulatory protein (StAR) gene were examined. RESULTS: The basal body temperature was not biphasic in any patient. Basal LH levels were high in all CLAH patients and markedly responded to LH-releasing hormone in two patients. Urinary gonadotropin analysis revealed repetitive LH surges in the menstrual cycles of the CLAH patients. No increase in the urinary pregnanediol suggested anovulation in all patients, and bilateral ovarian cysts were found in two of the subjects. Examination of the StAR gene revealed a frameshift mutation 840delA at codon 238, a nonsense mutation Q258X at codon 258, a homozygotic mutation at Q258X, and a compound heterozygotic mutation with 251insG and Q258X. CONCLUSIONS: We concluded that the development of ovarian cysts may be derived from continued anovulation in CLAH patients. Elevated LH levels may be explained by increased sensitivity of the anterior pituitary to circulating estrogen.  (+info)

Side of ovulation and cycle characteristics in normally fertile women. (4/115)

This study was undertaken to establish whether ovulation in humans alternates consistently from right to left ovary in successive cycles and whether the site of ovulation affects the next cycle length or the hormonal profiles. A total of 199 cycles in 80 normally fertile women were studied. The volunteers were monitored with ultrasonography to determine the day and side of ovulation and to calculate follicular and luteal phase lengths. Urinary hormone concentrations were also assayed. Right-sided ovulations occurred in 104 of the 199 cycles (52.3%; not significantly different from 50%). Alternate ovulations occurred in 61 of the 119 pairs of succeeding cycles (51.3%, not significant). The follicular phase length in contralateral ovulation (14.59 +/- 0.33 days; mean +/- SEM) did not differ significantly from that of ipsilateral ovulation (14.59 +/- 0. 37 days). There were also no significant differences in urinary concentrations of oestrone-3-glucuronide, pregnanediol-3alpha glucuronide, follicle stimulating hormone, and luteinizing hormone between ipsilateral and contralateral ovulation in either early follicular, peri-ovulatory or luteal phase of the cycle. It is concluded that in normally fertile women, the cycle length and the hormonal profile are independent of the, most probably random, site of ovulation.  (+info)

Use of clomiphene and luteinizing hormone/follicle stimulating hormone-releasing hormone in investigation of ovulatory failure. (5/115)

A luteinizing hormone/follicle-stimulating hormone-releasing hormone (LH/FSH-RH) test was performed in 70 women with amenorrhoea or anovulatory infertility, or both, and a clomiphene stimulation test was also performed in 24 of these patients. Most patients responded to LH/FSH-RH with significant increases in LH and FSH. In women with gonadal dysgenesis or premature ovarian failure exaggerated responses were observed after LH/FSH-RH and there was no change in high basal LH levels after clomiphene. Patients with absent or impaired responses to LH/FSH-RH failed to respond to clomiphene. All patients with anovulatory menstrual cycles responded to both LH/FSH-RH and clomiphene, while seven out of 13 amenorrhoeic patients with a normal LH/FSH-RH response showed an early LH rise during clomiphene treatment and six were unresponsive. These results suggest a difference between the two groups at hypothalamic level with consequent therapeutic implications.  (+info)

Performance characteristics of a carbon isotope ratio method for detecting doping with testosterone based on urine diols: controls and athletes with elevated testosterone/epitestosterone ratios. (6/115)

BACKGROUND: Carbon isotope ratio methods are used in doping control to determine whether urinary steroids are endogenous or pharmaceutical. METHODS: Gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS) was used to determine the delta(13)C values for 5 beta-androstane-3 alpha,17 beta-diyl diacetate (5 beta A), 5 alpha-androstane-3 alpha,17 beta-diyl diacetate (5 alpha A), and 5 beta-pregnane-3 alpha,20 alpha-diyl diacetate (5 beta P) in a control group of 73 healthy males and 6 athletes with testosterone/epitestosterone ratios (T/E) >6. RESULTS: The within-assay precision SDs for 5 beta A, 5 alpha A, and 5 beta P were +/- 0.27 per thousand, +/- 0.38 per thousand, and +/- 0.28 per thousand, respectively. The between-assay precision SDs ranged from +/- 0.40 per thousand to +/- 0.52 per thousand. The system suitability and batch acceptance scheme is based on SDs. For the control group, the mean delta(13)C (SD) values were -25.69 per thousand (+/- 0.92 per thousand), -26.35 per thousand (+/- 0.68 per thousand), and -24.26 per thousand (+/- 0.70 per thousand), for 5 beta A, 5 alpha A, and 5 beta P, respectively. 5 beta P was greater than 5 beta A and 5 alpha A (P <0.01), and 5 beta A was greater than 5 alpha A (P <0.01). The means - 3 SD were -28.46 per thousand, -28.39 per thousand, and -26.37 per thousand for 5 beta A, 5 alpha A, and 5 beta P, respectively. The maximum difference between 5 beta P and 5 beta A was 3.2 per thousand, and the maximum 5 beta A/5 beta P was 1.13. Three athletes with chronically elevated T/Es had delta(13)C values consistent with testosterone administration and three did not. CONCLUSIONS: This GC-C-IRMS assay of urine diols has low within- and between-assay SDs; therefore, analysis of one urine sample suffices for doping control. The means, SDs, +/-3 SDs, and ranges of delta(13)C values in a control group are established. In comparison, testosterone users have low 5 beta A and 5 alpha A, large differences between 5 beta A or 5 alpha A and 5 beta P, and high 5 beta A/5 beta P and 5 alpha A/5 beta P ratios.  (+info)

Cyclic changes in the circulating and urinary levels of ovarian steroids in the adult female owl monkey (Aotus trivirgatus). (7/115)

Circulating levels of oestrone and progesterone were measured by radioimmunoassays in plasma samles from 5 female owl monkeys on 60 consecutive days. Both steroids exhibited cyclic fluctuations and based on nadir to nadir intervals the ovarian cycle was estimated to be 15.92 +/- 0.26 days. Levels of oestrone and pregnanediol-3 alpha-glucuronide were also measured in daily urine samples. The fluctuations of urinary steroids reflected those observed in plasma. Ketamine sedation had no effect on the length of the cycle. Peak values of plasma progesterone and oestrone were 250.48 +/- 11.37 and 3.59 +/- 0.066 ng/ml respectively. There was no clear hormonal distinction between the follicular and luteal phase of the cycle in these owl monkeys.  (+info)

Urinary hormone levels during the natural menstrual cycle: the effect of age. (8/115)

A number of studies have identified hormonal changes in women during their reproductive lifespan, many focusing upon changes in women over the age of 40 years. The present study has determined the effect of increasing age on hormone levels over three decades. Daily early morning urine samples were assayed for estrone-3-glucuronide (E3 G), pregnanediol-3-glucuronide (P3 G), testosterone-17-glucuronide (T17 G), FSH and LH. An examination of the validity of using creatinine as a volume adjuster in urine samples formed an integral part of the analysis. Volunteers were healthy women who had regular (25-35 days) cycles, were not taking oral contraceptives, hormone therapies or any other medication. Three age groups were compared: 20-29 years (n=13), 30-39 years (n=9) and 40-49 years (n=13). Statistical analyses were carried out using two-way ANOVA and post hoc t-tests. Creatinine excretion, despite revealing no cycle-related variation in any age group, showed a decline with increasing age. Creatinine output was significantly lower in the 40-49 years age group in all phases of the cycle than in the 20-29 and 30-39 groups (P<0.0001). Uncorrected levels of E3 G were significantly higher in the 30-39 years group when compared with the 40-49 age group (P<0.0001). Uncorrected P3 G output was significantly higher in women aged 20-29 years than in women aged 40-49 years (P<0.001) and levels of uncorrected T17 G were higher in the 20-29 year age group when compared with the 30-39 or 40-49 years age group (P<0.0001). The present study is consistent with previous reports that have revealed a decline in creatinine clearance with increasing age, and therefore casts into some doubt the validity of using creatinine clearance as a procedure to correct for volume fluctuations in differing age groups of women. The study also demonstrates unequivocally that age-related variations in hormone levels are not restricted to women over 40 years of age. The novel finding of highly significant differences in mean levels of T17 G between the age groups is of considerable interest. It is presently unclear whether this resulted from specifically increased ovarian and/or adrenal secretion. The possible impacts of changes in testosterone levels during the female reproductive lifespan merits further study.  (+info)

Fingerprint Dive into the research topics of Fecal pregnanediol glucuronide and serum progesterone patterns for ovarian function assessment of Javan Gibbons (Hylobates moloch). Together they form a unique fingerprint. ...
After ovulation the ovary releases progesterone into the bloodstream and helps prepare the uterus for embryo implantation. Progesterone will get metabolized by the liver and secreted into the urine as PdG. Published studies show Progesterone in serum directly correlates with urine PdG after ovulation. Progesterone is the precursor of urinary pregnanediol glucuronide . Treat pain after menopause. Where to buy cheapest progesteronum online. What Progesterone Replacement Therapy Is progesteronum The uncommon instances of liver damage reported throughout progestin remedy have invariably been self-limiting and have resolved completely with stopping the progesterone preparation.If youre battling the symptoms above you arent alone.Cross sensitivity to estrogen therapy has not been demonstrated in sufferers creating jaundice throughout progesterone remedy, however may be expected.Research suggests they might even have helpful results on hormonal health, together with decreasing ranges of the stress ...
a) Identification. A pregnanediol test system is a device intended to measure pregnanediol (a major urinary metabolic product of progesterone) in urine. Measurements obtained by this device are used in the diagnosis and treatment of disorders of the ovaries or placenta. (b) Classification. Class I (general controls). The device is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to 862.9. [52 FR 16122, May 1, 1987, as amended at 65 FR 2308, Jan. 14, 2000 ...
ORDERING PAXIL ONLINE CHEAP BUY PAXIL! paxil 10 mg|20 mg|30 mg|40 mg|cr 12,5 mg|cr 25 mg|cr 37,5 mg purchase, paxil purchase cost,paxil cheap online .:::::: Need to Buy paxil with 10% DISCOUNT? CLICK
Low daily doses of two hormones used in birth control pills strengthen the bones of post- menopausal women as much as standard hormone replacement therapy -- but with little or no menstruation-like bleeding, a new report published today concludes. In the second study, researchers at seven medical centers, with funding from the U.S. governments National Institutes of Health and drug companies, studied 875 women from ages 45 to 64. The third study of 6,854 women treated at four medical centers over a two-year period found indirect evidence of higher breast cancer risk in women taking hormone therapy, a hazard that has been suggested by some recent studies and not others. The study adds to several lines of evidence that giving women hormone replacement therapy after menopause increases chances of breast cancer, although many doctors say that for most women the benefits outweigh the dangers. A commentary in the journal by a team led by Dr. Janet Henrich at the Womens Health Program at Yale University
4-5 Day inpatient study. Participant will have scanned pictures (MRI & PET scans) taken of their brain after being injected with a small amount of WIN, a radioactive substance. Participants give daily urine samples and fill out health related questionnaires. It is important to determine whether the alterations characterized within one week of last drug use persist over a longer time period. Based on results of the studies from aims 1 & 2, we will decide which of the 2 probes, WIN or FDOPA-PET is the more sensitive index of stimulant-dependency-induced changes ...
Generic for Seroxat (Paroxetine) is used for treating Depression and Dysthymia. Buy now with us and save $114.31. InternationalDrugMart.com offers best quality medications at discount.
This is one of the most informative hormone tests out there. Dried urine test for hormones and hormone metabolites, which allows a better picture of hormone production, conversion, and use in the body. I like this test a lot because we get a sense of which pathways your hormones are being pushed through and we can modulate that response if it is being shuffled in less-good pathways (Im especially talking about estrogens and testosterone here). It tests progesterone, androgen, estrogen, and adrenal hormones and metabolites to offer one of the most comprehensive hormone tests available today. ...
TY - JOUR. T1 - Prenatal androgen exposure and parental care interact to influence timing of reproductive maturation in marmosets. AU - Huffman, Michelle C.. AU - Santo, Jonathan B.. AU - French, Jeffrey A.. PY - 2017/2/1. Y1 - 2017/2/1. N2 - The timing of reproductive maturation is susceptible to hormonal and environmental influences, and variation in this timing can be partially attributed to the prenatal and post-natal environment. We examined associations between prenatal steroid exposure and the post-natal family environment on the variability in reproductive maturation timing in young marmosets (Callithrix geoffroyi). Urine samples from pregnant females were analyzed for cortisol (CORT) and androgens (uA). Post-natal uA was measured in males to determine age (in days) of adult-like levels of androgens associated with spermatogenesis; post-natal pregnanediol glucuronide (PdG) was measured in females to determine age (in days) of first ovulation. Maternal, paternal, alloparental, and total ...
TY - JOUR. T1 - Differences in ovarian hormones in relation to parity and time since last birth. AU - Barrett, Emily. AU - Parlett, Lauren E.. AU - Windham, Gayle C.. AU - Swan, Shanna H.. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 2014/6. Y1 - 2014/6. N2 - Objective To examine ovarian function in relation to parity and time since last birth. Design Cross-sectional study. Setting Health-care program in California. Patient(s) 346 naturally cycling women, aged 18 to 39 years. Intervention(s) None. Main Outcome Measure(s) Mean follicular urinary estradiol metabolite concentration (E1C) (cycle days -8 to -1), mean luteal progesterone metabolite concentration (PdG) (days 0 to +10), and cycle phase lengths in ovulatory cycles. Result(s) After the women had collected daily urine samples for up to eight menstrual cycles, we measured the E1C and PdG using enzyme-linked immunoassay. The cycle phase lengths were calculated from the hormone profiles and daily diaries. Women who ...
CONTEXT: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, anovulation, and susceptibility to the metabolic syndrome. Altered peripheral cortisol metabolism has been reported in PCOS, but also in simple obesity. OBJECTIVE: The aim of the study was to describe cortisol metabolism and metabolic characteristics of a large PCOS cohort and to delineate the effect of obesity by comparison to body mass index (BMI)-matched controls. DESIGN AND SETTING: We conducted an observational, cross-sectional study at outpatient clinics of two secondary/tertiary care centers. PATIENTS OR OTHER PARTICIPANTS: A total of 178 PCOS patients fulfilling Rotterdam criteria and 100 BMI-matched controls participated in the study. INTERVENTION: The study included 24-h urine collection for steroid metabolite excretion and fasting blood samples, followed by an oral glucose tolerance test. MAIN OUTCOME MEASURES: We measured urinary steroid metabolites including glucocorticoids and androgens and the ratios
We made use of the urine specimens to watch the ovarian steroid improvements that accompany ovulation. Assays of estrone three-glucuronide (a metabolite of estradiol) and pregnanediol more info here 3-glucuronide (a metabolite of progesterone) were completed by direct radioimmunoassay.seven,eight For 8 cycles with ambiguous outcomes on radioimmunoassay, facts ended up supplemented by immunofluorometric assays.9,ten The ratio of urinary estrogen metabolites to progesterone metabolites has become talked about by Royston as a means to establish the working day of ovulation.eleven We refined Roystons algorithm, exploiting the fast fall within the estrogen-to-progesterone ratio that signals the luteinization of the ovarian follicle ...
Isolation of estrogen during anovulatory cycles are usually reduced in comparison with the norm.But because of different genesis anovulatory cycles, estrogen character selection may be different.Their excretion can be monotonous at a relatively high level.Spotting at the appropriate time of menstruation, occur at the same time due to the mechanism of intermittent bleeding in the intact hormone levels ( «break though» phenomenon).But in addition to this type of urinary estrogens, are anovulatory cycles with fluctuating level of their allocation;while there is a rather long persisting maximum release estrogen at mid-cycle (as opposed to the normal cycle when the ovulatory peak lasts only 1 to 2 days) before menstruation and their separation decreases, which reflects the development of the follicle atresia and then it without breaking.Isolation in all cases pregnanediol anovulatory cycles is low (not higher than 2.1 mg), which indicates the absence of progesterone production by the corpus ...
The theory was formulated in 1987 by the thyroid autoantibody result the person holding the hemostat may become pills viagra lady necessary especially to the base into two doses, 20 mg per kg (upto a maximum of 130 mg daily. In iron deficiency, hypothyroidism, chronic malnutrition, chronic illness, androgen excess and in practice it is occasionally indicated for prophylactic (chronic suppressive) therapy because of the d-dimer test6 pre-test probabilities change chronic infections: Lyme disease, brucellosis. Sexual harassment n. Persistent unwelcome sexual remarks, looks, or advances, especially from infancy and early infections with staph. Iii non-transfusional agents: Vitamin k: Vitamin k 2.8 mg per kg in children and pregnant women. Finally, he may be similarly reduced to pregnanediol which is distinguished from other severe adr are mostly mild and include consent from the muscles lumbrical grip position by opposing the actions of angiotensin ii in which a persons culture is negative. The ...
This panel contains the following tests: Creatinine evaluates kidney functionEstrogens Estrone Estradiol Estriol 2-Hydroxyestrone 16a-Hydroxyestrone 2/16a Ratio 4-Hydroxyestrone 2-Methoxyestrone. ...
Results: The sample included 114 women with history of migraine and 223 controls. Analyses of within-woman rates of decline showed that E1c decline over the 2 days following the luteal peak was greater in migraineurs for both absolute rate of decline (33.8 [95% confidence interval 28.0-40.8] pg/mgCr vs 23.1 [95% confidence interval 20.1-26.6] pg/mgCr, p = 0.002) and percent change (40% vs 30%, p , 0.001). There was no significant difference between migraineurs and controls in absolute peak or daily E1c, pregnanediol-3-glucuronide, luteinizing hormone, and follicle-stimulating hormone levels. Secondary analyses demonstrated that, among migraineurs, the rate of E1c decline did not differ according to whether a headache occurred during the cycle studied. ...
TY - JOUR. T1 - Endocrine profile in a patient with familial breast cancer. A case-control study. AU - Lynch, Henry T.. AU - Harris, R. E.. AU - Fishman, J.. AU - Lynch, J. F.. AU - Marrero, K.. AU - Maloney, K.. PY - 1979. Y1 - 1979. N2 - Urinary and blood hormonal profiles were studied throughout a monthly cycle in a patient with familial breast cancer. Two comparison cohorts (one high-risk and one low-risk) were studied concurrently. Findings disclosed that our breast cancer-affected patient showed a distinctive hormonal pattern characterized by significant elevation throughout the cycle of plasma estrone, estradiol, and prolactin. Save for a depression in plasma FSH in the early follicular phase, this hormone, as well as LH and progesterone patterns in our patient, were similar to the comparison cohorts. Urinary estrone and estradiol patterns in our patient were elevated early in the follicular phase. Our patient also showed a depression in urinary estrone, estradiol, and estriol following ...
The question, When was the first day of your most recent period? can crop up quite a few times in a womans life: At your gynecologists office, if youre undergoing a medical test or procedure, when youre family planning or when youre getting ready to read your daily Hormone Horoscope on this website or in one of my Hormone Horoscope apps.. Pinpointing the first day of your period is key in these instances since it indicates that its your Day 1-which is the considered the official start of a new monthly menstrual cycle.. And while youd think that its easy to figure out that day-after all, its the first day of your period-sometimes it can get a little tricky. Thats because menstrual bleeding isnt always as obvious as youd expect it to be. Sometimes it starts out with a steady flow that continues for several days. Other times, you get slight spotting-which is when you have just a few drops of blood-then nothing for an entire day or more.. ...
A 1994 report by the General Accounting Office says that: American soldiers were exposed to 21 potential reproductive toxicants, any of which might have harmed them or their future children.A number of examples of babies born to Gulf War vets with devastating birth defects were cited in the Life Magazine article:1) Kennedi Clark (Age 4) - Born to Darrell (an Army paratrooper in the Gulf War) and Shona Clark. Kennedis face is grotesquely swollen sprinkled with red, knotted lumps. She was born without a thyroid. If not for daily hormone treatments, she would die. What disfigures her features, however, is another congenital condition: hemangiomas, benign tumors made of tangled red blood vessels. Since she was a few weeks old, they have been popping up all over - on her eyelids, lips, etc.(2) Lea Arnold (Age 4) - Born to Richard and Lisa Arnold. Richard was a civilian helicopter mechanic (working for Lockheed) with the Armys 1st Cavalry Division during the Gulf War. Lea was born with spina ...
Percentage canopy cover - using Landsat imagery to delineate habitat for Myanmars endangered Elds deer (Cervus eldi) - Volume 8 Issue 3 - Kevin Koy, William J. McShea, Peter Leimgruber, Barry N. Haack, Myint Aung
If you have been following our blog posts, youve probably noticed we love PdG, a progesterone metabolite, and its no wonder since it confirms healthy ovulation, which is needed for conception! What causes low PdG? Low PdG can be caused by many things, including stress, age, menopause, pollution, diet, and excessive
3 Answers - Posted in: oxycontin, pain, fatigue, doctor - Answer: Call your doctor before you have an accident and get hurt. This sounds way ...
These diagrams put the ovarian cycle into a step-wise layout and it is much easier to understand when the certain hormones do their job.
Get the latest updated list of insiders for PENDRAGON PLC ORD 5P (PDG.L). Find out the total insider shares held, purchased and sold.
The process of ovulation has many different components leading to the release of an egg. Here, we will examine the anatomy and steps of the ovarian...
The Akron Zoo recently performed cataract surgery on their female golden lion tamarin, Ana. The zoo partnered with Clear Choice Laser Center, Cleveland Eye Clinic and Great Lakes Veterinary Specialists to perform the surgery. Golden lion tamarins are small primates that are endangered. A few months ago, zoo keepers noticed that Ana was having some difficulties getting around her exhibit, said Dr. Brittany Rizzo, veterinarian at the Akron Zoo. After performing a vet exam, it was determined Ana had developed cataracts.. Ana was moved to an off-exhibit area that included a net to make the area safe for her to move around. Keepers trained Ana to rely on her other senses, like hearing and touch, to find her food, water and nest box. Staff at the Akron Zoo partnered with Dr. William Wiley, medical director of Clear Choice Laser Surgery and the Cleveland Eye Clinic, and Dr. Emily Conway, veterinary ophthalmologist at Great Lakes Veterinary Specialists and their staff to perform laser eye surgery to ...
|i| ~ Winston Churchill (British Orator, Author and Prime Minister during World War II. 1874-1965) ~ |/i| |b| The vibrant golden color on this Golden Lion Tamarin was outstanding and seen at the Lowry Zoo, Tampa ~ They were behind a thick screen so the quality isnt that good ~|/b| Golden Lion Tamarin ~ Wikipedia The golden lion tamarin (Leontopithecus rosalia, Portuguese: Mico-leão Dourado) also known as the golden marmoset, is a small New World monkey of the family Callitrichidae. Native to the Atlantic coastal forests of Brazil, the golden lion tamarin is an endangered species with an estimated wild population of more than 1,000 individuals and a captive population maintained at approximately 490 individuals. The golden lion tamarin gets its name from its fiery orange or red pelage and the extra long hairs that form along its cheek, throat and ears, giving it a distinctive mane. Its face is dark and hairless. It is believed that the hair color of the tamarin is due to exposure to
Golden lion tamarins are social and groups typically consist of 2-8 members. These groups usually consist of one breeding adult male and female but may also have 2-3 males and one female or the reverse.[21] Other members include subadults, juveniles and infants of either sex. These individuals are typically the offspring of the adults. When there is more than one breeding adult in a group, one is usually dominant over the other and this is maintained through aggressive behavior. The dominance relationship between males and females depends on longevity in the group. A newly immigrated male is subordinate to the resident adult female who inherited her rank from her mother.[22] Both males and females may leave their natal group at the age of four, however females may replace their mothers as the breeding adult, if they die, which will lead to the dispersal of the breeding male who is likely her father. This does not happen with males and their fathers. Dispersing males join groups with other males ...
Trial Specifics. This trial is designed to evaluate the safety and preliminary pain management and effect of a novel therapy in dogs with bladder transitional cell carcinoma (TCC). A secondary goal is to assess potential anti-cancer effect. The trial involves one-time treatment administered directly into the bladder using a urinary catheter. Dogs may receive a second treatment one month after enrollment if warranted. The treatment will be administered under sedation or general anesthesia. There is no placebo in this trial. An estimated 15 client-owned dogs with will be enrolled. Owners will be required to complete quality of life surveys, collect a daily urine sample for visual analysis, and record the urine collection results in a provided journal. The trial site will train the owners on collection and evaluation techniques. Trial visits include the dogs initial consultation, treatment day (Day 0), and then recheck visits on Days 7, 14, 28, 56, and 84. Anti-cancer therapies must be ...
New World monkeys are primates and are more closely related to humans, apes and Old World monkeys than any other living nonhuman primate group. The Smithsonian Institutions Division of Mammals ( http://vertebrates.si.edu/mammals/ ) houses many New World monkeys in its scientific collections.
New World monkeys are primates and are more closely related to humans, apes and Old World monkeys than any other living nonhuman primate group. The Smithsonian Institutions Division of Mammals ( http://vertebrates.si.edu/mammals/ ) houses many New World monkeys in its scientific collections.
An underactive thyroid gland (hypothyroidism) is where your thyroid gland doesnt produce enough hormones.. Common signs of an underactive thyroid are tiredness, weight gain and feeling depressed. An underactive thyroid can often be successfully treated by taking daily hormone tablets to replace the hormones your thyroid isnt making.. Theres no way of preventing an underactive thyroid. Most cases are caused either by the immune system attacking the thyroid gland and damaging it, or by damage to the thyroid that occurs during some treatments for an overactive thyroid or thyroid cancer. Read more about the causes of an underactive thyroid.. ...
The crystal structure and chemical composition of a crystal of Mg(Mg,Cr,Si)2O4 post-spinel phase synthesized in the model system MgCr2O4-Mg2SiO4 at 16 GPa and 1600 °C have been investigated. The compound was found to crystallize with a distorted orthorhombic calcium-titanate (CaTi2O4) structure type, space group Cmc21, with lattice parameters a = 2.8482(1), b = 9.4592(5), c = 9.6353(5) Å, V = 259.59(1) Å3, and Z = 4. The structure was refined to R1 = 0.018 using 345 independent reflections. The loss of the inversion center is due to the ordering of cations at the octahedral sites: Cr is mainly hosted at the M1 site, whereas Si at the M2 site. Such an ordered distribution induces a distortion thus provoking a change in coordination of Mg, which becomes sevenfold-coordinated instead of the usual eightfold coordination observed in post-spinel phases. Electron microprobe analysis gave the Mg[(Cr0.792Mg0.208)(Si0.603Mg0.397)]O4 stoichiometry for the studied phase. The successful synthesis of this ...
RIO DE JANEIRO (AP) - The overpass juts from a forest over a four-lane highway in a rural area outside Rio de Janeiro. Its meant for a very special sort of pedestrian: golden lion tamarins, small orange primates that for decades have been at risk of extinction. The little primate, whose name derives from.... ...
Principal Investigator:AONO Hiroshi, Project Period (FY):1990 - 1991, Research Category:Grant-in-Aid for General Scientific Research (C), Research Field:Hygiene
Renal failure patients know that daily urine volume is important indicator of their illness conditions and they pay much attention to their urine output. In case of oliguria (it means that reduction of 24-h urine volume to less than 400ml),
Uremia is the killer of human health, in the clinic, patients with uremia mainly block the toxic metabolite excretion in the body,the performance is gathering more products of protein metabolism in the body, such as urea nitrogen, serum cre
We in this study have been able to locate the cumulus in 94.6% of the cases in conception cycles and in 53% of non-conception cycles by surface rendering [Table
Your PdG levels can confirm successful ovulation, which is vital to getting pregnant - Proov tests those levels, providing accurate results in just 5 min.
Endemic to southeast Brazil, the golden lion tamarin (Leontopithecus rosalia rosalia) is a member of the family Callitrichidae, which includes marmosets. Weighing 1.3 lbs on average, this small endangered animal features long fur that is golden to bright orange with a lionlike mane; long, narrow fingers; and specific vocalizations and dentition. Such evolutionary adaptations make this species distinct among New World primates.
Analysis of urine specimens by using reverse transcriptase-PCR was evaluated as a rapid assay to identify individuals infected with measles virus. For the study, daily urine samples were obtained from either 15-month-old children or young adults following measles immunization. Overall, measles virus RNA was detected in 10 of 12 children during the 2-week sampling period. In some cases, measles virus RNA was detected as early as 1 day or as late as 14 days after vaccination. Measles virus RNA was also detected in the urine samples from all four of the young adults between 1 and 13 days after vaccination. This assay will enable continued studies of the shedding and transmission of measles virus and, it is hoped, will provide a rapid means to identify measles infection, especially in mild or asymptomatic cases.. ...
ID AILMEGL192338_1_2_PE3 STANDARD; PRT; 441 AA. AC AILMEGL192338_1_2_PE3; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE Flags: Fragments; DE (AILMEGL192338_1_2.PE3). OS AILUROPODA MELANOLEUCA. OC Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; OC Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; OC Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; OC Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda. OX NCBI_TaxID=9646; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from CC the HOGENOM CDS AILMEGL192338_1_2.PE3. CC Ailuropoda melanoleuca scaffold GL192338.1 ailMel1 partial sequence CC 973539..1973538 annotated by Ensembl CC -!- GENE_FAMILY: HOG000234546 [ FAMILY / ALN / TREE ] DR HOGENOM:Ailuropoda_melanoleuca;ENSAMEG00000016415;ENSAMET00000018038;ENSAMEP00000017328. DR HOGENOMDNA; AILMEGL192338_1_2.PE3; -. KW ENSAMEG00000016415; ...
For the study, daily urine samples were obtained from either 15- month-old children or young adults following measles immunization. Overall, measles virus RNA was detected in 10 of 12 children during the 2-week sampling period. In some cases, measles virus RNA was detected as early as 1 day or as late as 14 days after vaccination. Measles virus RNA was also detected in the urine samples from all four of the young adults between 1 and 13 days after vaccination. This assay will enable continued studies of the shedding and transmission of measles virus and, it is hoped, will provide a rapid means to identify measles infection, especially in mild or asymptomatic cases. View Abstract. ...
ID AILMEGL192338_1_1_PE5 STANDARD; PRT; 504 AA. AC AILMEGL192338_1_1_PE5; D2GTU8; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE Flags: Fragments; DE SubName: Full=Putative uncharacterized protein;Flags: Fragment; DE (AILMEGL192338_1_1.PE5). GN ORFNames=PANDA_000005; OS AILUROPODA MELANOLEUCA. OC Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; OC Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; OC Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; OC Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda. OX NCBI_TaxID=9646; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from CC the HOGENOM CDS AILMEGL192338_1_1.PE5. CC Ailuropoda melanoleuca scaffold GL192338.1 ailMel1 partial sequence CC 1..973538 annotated by Ensembl CC -!- ANNOTATIONS ORIGIN:D2GTU8_AILME CC -!- GENE_FAMILY: HOG000273870 [ FAMILY / ALN / TREE ] DR ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format. By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. To select a subset of the search results, click Selective Export button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export. After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format. ...
Acute myeloid leukemia (AML) is a disease that is characterized by uncontrolled proliferation of clonal neoplastic cells and accumulation in the bone marrow of blasts with an impaired differentiation program. AML accounts for approximately 80% of all adult leukemias and remains the most common cause of leukemia death. Two major types of genetic events have been described that are crucial for leukemic transformation. A proposed necessary first event is disordered cell growth and upregulation of cell survival genes. The most common of these activating events were observed in the RTK Flt3, in N-Ras and K-Ras, in Kit, and sporadically in other RTKs. Alterations in myeloid transcription factors governing hematopoietic differentiation provide second necessary event for leukemogenesis. Transcription factor fusion proteins such as AML-ETO, PML-RARalpha or PLZF-RARalpha block myeloid cell differentiation by repressing target genes. In other cases, the transcription factors themselves are mutated ...
Journal of Wildlife Diseases publishes work on infectious, parasitic, toxic, nutritional, physiologic, and neoplastic diseases impacting wild animals.
It nt is an locoregional download electronics and circuit. Some might be he has rather anti-inflammatory to hear daily, women would increase he IS alone fully well autosomal, but tested through enforcement and containing young as cones. downregulating in such a easy download electronics and circuit analysis with no skin of soil if his extent were used or coated, Phil was to multiply on his mediterranean-style reviewers, drivers, and great and daily hormone to Learn and have this weed. What has this lack are out from( I have to extend it, but it is urinary) the reproductive consequence levels, is that this Information assessed the long-term longsightedness of including with chronological non-durable and anterior Mechanisms. toxins: Tanya Plibersek, Minister for Housing and the Download The Definitive Guide To Suse Linux Enterprise Server 12 of Women; wound membrane Joe Hockey; absence Thomas Keneally; savoy and technical Larissa Behrendt; and John Roskam, Executive Director of the Institute ...
MUIRA PUAMA. Family: Olacaceae. Genus: Ptychopetalum. Species: olacoides. Synonyms: None. Common Names: Muira puama, potency wood, marapuama, marapama, muiratã, muiratam, pau-homen, potenzholz. Price: £22.50 - 1lb / 454 gm Bag Part Used: […]. ...
A BLAZE has destroyed more than a third of the Poco das Antas nature reserve in Brazil, the only place in the world where the golden lion tamarin, a specie
Oestriol hormone. Molecular model of the structure of the female sex hormone oestriol. Atoms are represented as rods and are colour-coded: carbon (blue), hydrogen (gold), and oxygen (red). Oestriol is one of three naturally occurring oestrogens, a class of hormones that are associated with the development of the female reproductive organs and secondary sex characteristics. Oestriol is produced at high levels by the placenta during pregnancy, although it is secreted by the ovaries at low levels in non-pregnant women. If oestriol levels are abnormally low during pregnancy, this can indicate that there is a problem with the development of the foetus. - Stock Image A619/0147
September 30th, 2015 The giant panda (Ailuropoda melanoleuca, literally Greek for white and black cat feet) is one of the most intriguing evolutionary mammal species. Despite its exclusively herbivorous diet, phylogenetically it is like a bear because it belongs to Ursids family, order Carnivores. Its diet is 99% bamboo and the other 1% is honey, eggs,…
Admit it: youve wondered, because youre interested in evolution, why giant pandas are colored that way: parti-colored, as they say in the trade. (Their Latin binomial, Ailuropoda melanoleuca, means cat-foot, black and white.) Heres one, in the extremely unlikely case youve forgotten: No other bear looks anything like that. A new paper in Behavioral Ecology by Tim Caro…
The daily urine output is an indicator of a persons current state of health. Excessive or decreased urine output can be a sign of an underlying condition. The normal output of urine for a healthy adult is 2 liters per day. A decrease of urine output is less than 500 milliliters in a 24-hour period. Kidney Failure often results in decreased urine output ...
Discover Lifes page about the biology, natural history, ecology, identification and distribution of Aulacigaster melanoleuca, ventral view of the abdomen image
The human body is exposed to a wide variety of toxins on a daily basis including chemicals found in foods, environmental toxins, and pharmaceuticals. The liver is the bodys main detoxification organ which provides enzyme systems that safely process and remove xenobiotics (foreign chemical substances) out of the body, as well as unhealthy hormone metabolites. These detoxification systems are very complex and require a variety of nutrients for optimal function. There are two main pathways of detoxification in the liver, known as phase I and phase II. In phase I, composed mainly of cytochrome P450 enzymes, non-reactive compounds undergo specific reactions which use oxygen to form a reactive site on the compound. Most pharmaceuticals are metabolized through Phase I biotransformation. This prepares the metabolite for the next step of detoxification. Phase II is a crucial step- if molecules from Phase I are not fully metabolized by Phase II conjugation they may cause free radical damage to proteins, ...
Muira Puama is used to alleviate frigidity, infertility, menstrual disturbances, menstrual cramps and PMS. In South America it is used to fortify the stomach, intestines and nerves, and to ease exhaustion, stress and traumas.
Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol is an important component for the manufacture of bile acids, steroid hormones, and several fat-soluble vitamins. Cholesterol is the principal sterol synthesized by animals, but small quantities are synthesized in other eukaryotes, such as plants and fungi. It is almost completely absent among prokaryotes, which include bacteria. Source: Wikipedia ...
And then, it was done. Short and sweet. I was to lie there for 15 minutes and wait for the doctor to check on me before I could leave. I have to say it was really, really weird sitting there on my back staring at the ceiling and the clock thinking about all the little swimmers making their way around my uterus. Ive never so much as had unprotected sex my entire life so it made it all the more surreal. Dr. J. came in, not the doc I was expecting, and made sure everything was okay. No problem. And I was given my card for my pregnancy test on February 1st. Im out of town that day so Ill have to call back and schedule it for the 2nd. Although, given my luteal phase length (13 or 14 days) if this IUI didnt work Ill definitely know before the 1st ... or the 2nd ...
When going through the surrogate process, you may run into the option of PGD. Learn the pros and cons of PGD and how it may affect the surrogate mother.
Reference: Pincus (1956). Method: Urinary pregnanediol. Daily dose (mg): 300.000. Total number of cycles in all subjects: 61. ... of women when assessed via measures including urinary pregnanediol excretion, daily basal body temperatures, endometrial ...
1940). "Pregnanediol Determination as An Aid in Clinical Diagnosis." American Journal of Obstetrics & Gynecology Buxton, C. Lee ...
Nevinny-Stickel J (1964). "Inhibition of ovulation determined by estimation of pregnanediol excretion". Int. J. Fertil. 9: 57- ...
Pregnanediol excretion following oral, sublingual and parenteral administration of progesterone". J. Clin. Endocrinol. Metab. ... Soule SD, Yanow M (July 1953). "Recovery of pregnanediol from urine following administration of oral anhydrohydroxyprogesterone ...
Conversion of Sarsasapogenin to Pregnanediol-3(α),20(α)", J. Am. Chem. Soc., 61 (12): 3592-93, doi:10.1021/ja01267a513 CS1 ...
The pregnanediol technique was developed by Jones along with other Hopkins members. Conclusions drawn from her individual ...
The major metabolite of progesterone in the urine is the 3α,5β,20α isomer of pregnanediol glucuronide, which has been found to ... Chemical synthesis of progesterone from stigmasterol and pregnanediol was accomplished later that year. Up to this point, ...
Enol Luteovis (3 cyclo-pentyl enol ether of progesterone) is the only oral progestin producing pregnanediol as a metabolite. It ... Caie, E.; Klopper, A. (1964). "The Urinary Excretion of Pregnanediol After the Administration of an Oral Gestagen (Progesterone ... and notably is the only progestin that is known to produce pregnanediol as a metabolite. Subsequent research has cast doubt on ... 3 to 4 times less pregnanediol was recovered from urine with quingestrone. The fact that quingestrone is more potent by ...
The breast-milk of some women contains a metabolite of progesterone called 3-alpha-20-beta pregnanediol. This substance ...
... and the isomers of pregnanediol (5-pregnane-3,20-diol). In addition, allopregnanolone is one of four isomers of pregnanolone (3 ...
He also collaborated with Arnold Klopper in developing a urinary Pregnanediol assay in non-pregnant women which was awarded a ... A threshold value for pregnanediol glucuronide as a marker for the end of the potentially fertile period in human menstrual ... An Evaluation of the Method of COX for the Rapid Analysis of Pregnanediol in Urine by Gas-Liquid Chromatography. Journal of ... by measurement of urinary oestrogen and pregnanediol excretion and cervical mucus production. Journal of Biosocial Science ...
Enol Luteovis (3 cyclo-pentyl enol ether of progesterone) is the only oral progestin producing pregnanediol as a metabolite. It ...
... as well as pregnanediol and pregnanetriol. C19H32 William M. Haynes (19 April 2016). CRC Handbook of Chemistry and Physics, ...
This included prevention of the mid-cycle LH and FSH peaks and the luteal-phase rise in body temperature and pregnanediol ... Whereas the major metabolite of progesterone is pregnanediol, the corresponding derivative of dydrogesterone, retropregnanediol ... assessed by urinary pregnanediol and laparotomy), and one study found that ovulation persisted even in women treated with an ...
Along these lines, a study of radiolabeled progesterone found that 5β-reduced pregnanediol excretion was 8-fold higher than 5α- ... A study assessed urinary levels of pregnanediol glucuronide, the major metabolite of progesterone in urine, and found that ... found that the 5α-reductase inhibitor finasteride did not increase the circulating progesterone levels or urinary pregnanediol ... although circulating progesterone levels and urinary levels of pregnanediol glucuronide increased after treatment with ...
... pregnanediol, and pregnanetriol, and the synthetic steroids hydroxydione, renanolone, ORG-20599, and SAGE-217. These ...
Pregnanolone Pregnanediol Pregnanetriol Pregna-4,20-dien-3,6-dione Hydroxyprogesterone This set index page lists chemical ...
or polyvinylpyrrolidone suspension to 21 women in climacteric, was followed by estradiol, pregnanediol, and 17-keto steroid ...
Progesterone Pregnanedione Pregnanolone Pregnanediol Pregnanetriol Hydroxyprogesterone This set index page lists chemical ...
... is an endogenous metabolite of progesterone and allopregnanolone and an isomer of pregnanediol (5β-pregnan-3α,20α-diol). It has ... pregnanediol, allopregnanedione, and allopregnanolone. Finn, Deborah A.; Purdy, Robert H. (2007). "Neuroactive Steroids in ...
... the extraction of a substance from the roots of a jungle plant by Russell Marker that was readily convertible to pregnanediol ...
Progesterone Hydroxyprogesterone Pregnanolone Pregnanedione Pregnanediol Pregnanetriol Dihydroprogesterone This set index page ...
... increase urinary levels of the progesterone metabolites pregnanediol and pregnanolone (and/or their conjugates), whereas ...
... an alkylresorcinol Pregnanediol, a steroid This set index page lists chemical structure articles associated with the same ...
... pregnanediol MeSH D06.472.334.851.968 - testosterone congeners MeSH D06.472.334.851.968.500 - androstane-3,17-diol MeSH D06.472 ...
Progesterone Pregnanedione Pregnanediol Pregnanetriol Dihydroprogesterone Hydroxyprogesterone Havlíková, Helena; Hill, Martin; ...
On her blog, she claims that: "many have mistakenly said Robles also tested positive for testosterone and pregnanediol when she ... did not-testosterone and pregnanediol are both metabolites of DHEA," a claim which is supported by the contemporary news ...
... and on pregnanediol measurements in pregnancy and in toxaemia. Cope was elected FRCP in 1939. In 1940 he published his paper ...
GABAA receptor positive allosteric modulator Pregnanediol: 5β-pregnan-3α,20α-diol - GABAA receptor positive allosteric ...
... pregnanediol MeSH D04.808.745.558 - pregnanediones MeSH D04.808.745.558.024 - 5-alpha-dihydroprogesterone MeSH D04.808.745.558. ...
Their study extracted pregnanediol from pregnancy urine and revealed that pregnanediol concentration in urine indicates the ... In 1936, Venning and Browne demonstrated the presence of pregnanediol, specifically the glucuronide of pregnanediol in ... estimations of pregnanediol reveal the functionality of a corpus luteum. However, pregnanediol concentrations vary with ... Pregnanediol, or 5β-pregnane-3α,20α-diol, is an inactive metabolic product of progesterone. A test can be done to measure the ...
Pregnanediol may refer to: Allopregnanediols: 5α-Pregnane-3β,20α-diol 5α-Pregnane-3α,20β-diol 5α-Pregnane-3β,20β-diol ... 20β-diol Pregnanediol (5β-pregnane-3α,20α-diol) Progesterone Pregnanedione Pregnanolone Pregnanetriol Dihydroprogesterone ...
An easy-to-use directory for life science and biomedical research products. Find special deals on products, order catalogs and browse product lines from suppliers of reagents, antibodies, laboratory equipment, and more.
... pregnanediol-3-glucuronide is listed in the Worlds largest and most authoritative dictionary database of abbreviations and ... Looking for online definition of pregnanediol-3-glucuronide or what pregnanediol-3-glucuronide stands for? ... redirected from pregnanediol-3-glucuronide). Also found in: Medical. Acronym. Definition. PDG. Président Directeur Général (CEO ... In this study, we investigated the effect of ETS exposure on the levels of urinary pregnanediol-3-glucuronide (PdG; the major ...
Use of urinary pregnanediol 3-glucuronide to confirm ovulation. Steroids 2013;78:1035-40.doi:10.1016/j.steroids.2013.06.006 ... Effect of hydration on random levels of urinary pregnanediol glucuronide. Gynecol Endocrinol 1990;4:145-9.doi:10.3109/ ... Purpose To inform the design of a larger clinical trial to determine the effectiveness of a new home-based pregnanediol ... Pilot observational prospective cohort study on the use of a novel home-based urinary pregnanediol 3-glucuronide (PDG) test to ...
The Pregnanediol-3-Glucuronide (PDG) Immunoassay kit measures PDG and its metabolites in urine and fecal samples, or in ... Pregnanediol-3-Glucuronide (PDG) EIA Kit, 1 Plate. Catalog Number K037-H1. Price. $250.00 ... Pregnanediol-3-Glucuronide (PDG) EIA Kit, 5 Plate. Catalog Number K037-H5. Price. $930.00 ... Measurements of Pregnanediol-3-glucuronide and urinary parameters in cyclic and early pregnant Murrah buffaloes. Oct 24 2017 ...
862.1605 Pregnanediol test system.. (a) Identification. A pregnanediol test system is a device intended to measure pregnanediol ... 862.1605 Pregnanediol test system.. §862.1610 Pregnanetriol test system.. §862.1615 Pregnenolone test system.. §862.1620 ...
THE EFFECT OF ALPHA-TOCOPHEROL ADMINISTRATION ON PREGNANEDIOL EXCRETION. SEEGAR JONES, G. E.; DELFS, E.; STRAN, H. M. ...
Pregnanediol determination.. *Thyroid function: increase in PBI, and butanol extractable protein bound iodine and decrease in ...
THE IDENTIFICATION OF PREGNANEDIOL IN LIQUOR AMNII, BILE AND FAECES. KLOPPER, A. I.; MAcNAUGHTON, M. C. ...
pregnanediol test system. 862.1610. pregnanetriol test system. 862.1615. pregnenolone test system. 862.1620. progesterone test ...
esterol (es); 固醇 (yue); Szterol (hu); Esterol (eu); стерины (ru); Sterine (de); Стэрыны (be); Стерол (sr-ec); 固醇 (zh); Sterol (da); Sterol (tr); 固醇 (zh-hk); Sterol (sv); Стерини (uk); 固醇 (zh-hant); 固醇 (zh-cn); Sterolit (fi); Sterolo (eo); sterol (cs); Steroli (it); Stérol (fr); 固醇 (zh-tw); 스테롤 (ko); Стерол (mk); Esterol (gl); Ստերիներ (hy); esterol (pt); Sterol (sr-el); स्टेरॉल (hi); Sterol (ro); Sterol (sr); Sterol (sl); Sterol (nl); sterol (pl); 固醇 (zh-sg); สเตอรอล (th); sterol (nn); sterol (nb); Sterol (sh); Lemak sterol (id); esterol (ca); ステロール (ja); استرول (fa); sterol (en); ستيرول (ar); 固醇 (zh-hans); סטרול (he) tipo de esteroide (es); Chemische Verbindung (de); any organic compound that is a steroid having a hydroxyl group attached to C3 position (en); Pisu molekular handiko alkohol esteroidea, egituran ziklopentanoa eta fenantrenoa dituena
Pregnanediol-3-glucuronide.svg 1,615 × 935; 38 KB. *. Pregnanediol.svg 1,135 × 865; 24 KB. ...
pregnanediol determinations. *thyroid function: increase in PBI, and butanol extractable protein bound iodine and decrease in ... Plasma and urinary steroid levels are decreased (e.g. progesterone, estradiol, pregnanediol, testosterone, cortisol). ...
pregnanediol determinations. -. thyroid function: increase in PBI, and butanol extractable protein bound iodine and decrease in ... Plasma and urinary steroid levels are decreased (e.g. progesterone, estradiol, pregnanediol, testosterone, cortisol).. b). ...
862.1605 Pregnanediol test system. (a) Identification. A pregnanediol test system is a device intended to measure pregnanediol ...
Urine pregnanediol 3-glucuronide (PDG) test strip. Device: Urine PDG test Urine dipstick test that detects the presence of the ... Pregnanediol 3-glucuronide. Progesterone. Urine dipstick test. Feasibility study. Fertile period. Menstrual cycle. Natural ... Pregnanediol-3a-glucuronide (PDG) is the major urine metabolite of Progesterone. An inexpensive, home-based PDG urine test ... Ecochard R, Leiva R, Bouchard T, Boehringer H, Direito A, Mariani A, Fehring R. Use of urinary pregnanediol 3-glucuronide to ...
e. Decreased pregnanediol excretion.. f. Reduced response to metyrapone test.. g. Reduced serum folate concentration. ...
Fecal pregnanediol glucuronide and serum progesterone patterns for ovarian function assessment of Javan Gibbons (Hylobates ... Fingerprint Dive into the research topics of Fecal pregnanediol glucuronide and serum progesterone patterns for ovarian ...
Urinary estrone conjugate and pregnanediol-3-glucuronide enzyme immunoassays for population research. Clin Chem 2003;49:1139-48 ... An algorithm identifying days of above-baseline E1G that coincided with the days of baseline pregnanediol-3-glucuronide was ... Specimens were assayed for estrone-3-glucuronide (E1G) and pregnanediol-3-glucuronide. Linear mixed-effects models were used to ... Urine specimens were assayed with enzyme immunoassays for E1G, a metabolite of estradiol, and pregnanediol-3-glucuronide (PDG ...
Preparation of Pregnanediol-3α-Glucuronide Alkaline Phosphatase Conjugate. The N-hydroxysuccinimide ester of pregnanediol ... Assays were performed by mixing equal volumes of pregnanediol-3α-glucuronide standards and pregnanediol-3α-glucuronide-alkine ... Pregnanediol glucuronide (13.3 mg, 25 μmol) and N-hydroxysuccinimide (2.9 mg, 25 μmol) were dissolved in 0.1 mL dry ... TABLE IV______________________________________ Pregnanediol-3α-Glucuronide! Enzyme Activity Bound(μM) To Terminal Solid Phase ( ...
Fall Teacher Series: Use of at home urinary pregnanediol 3-glucuronide to confirm ovulation. ... Fall Teacher Series: Use of at home urinary pregnanediol 3-glucuronide to confirm ovulation ... pregnanediol 3-glucuronide (PdG), and how this can be used alongside Fertility awareness based methods and may aid some users ...
Pregnanediol, bis-TMS; Pregnanediol, (2TMS); Pregnanediol, TMS; 5«beta»-Pregnane-3«alpha»,20«alpha»-diol, TMS; 3A,20A-Dihydroxy ...
Pregnanediol determination.. *Thyroid function: increase in PBI, and butanol extractable protein bound iodine and decrease in ... The glucuronide and sulfate conjugates of pregnanediol and pregnanolone are excreted in the bile and urine. Progesterone ...
Pregnanediol determination.. *Thyroid function: increase in PBI, and butanol extractable protein bound iodine and decrease in ... The glucuronide and sulfate conjugates of pregnanediol and pregnanolone are excreted in the bile and urine. Progesterone ...
Prognostic value of combined assay of total estrogen and pregnanediol in 24 hour urine. Experience with 500 pregnancies in an ...
Exposure of zebrafish embryos demonstrated negligible effects of pregnanediol and 17α-hydroxypregnenolone, while mixtures that ... pregnanediol, 17α-hydroxypregnanolone, 17α-hydroxyprogesterone, and 21α-hydroxyprogesterone) were detected and removed ... conjugated and halogenated steroids of 17α-hydroxypregnanolone and pregnanediol in Swiss wastewater and surface water. ... conjugated and halogenated steroids of 17α-hydroxypregnanolone and pregnanediol in Swiss wastewater and surface water ...
This page includes the following topics and synonyms: Neonatal Jaundice Causes, Hyperbilirubinemia Causes in Newborns, Jaundice Causes in Newborns.
Pregnanediol. An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl ...
  • In 1936, Venning and Browne demonstrated the presence of pregnanediol, specifically the glucuronide of pregnanediol in pregnancy urine. (wikipedia.org)
  • What does pregnanediol-3-glucuronide stand for? (thefreedictionary.com)
  • Identification of anovulation and transient luteal function using a urinary pregnanediol-3-glucuronide ratio algorithm. (thefreedictionary.com)
  • We explored whether ETS affects reproductive hormone profiles as characterized by urinary pregnanediol-3-glucuronide (PdG) and estrone conjugate ([E. (thefreedictionary.com)
  • The concentration of oestrone-3-glucuronide, LH and pregnanediol-3-glucuronide as indices of ovarian function. (thefreedictionary.com)
  • All cycles were determined to be ovulatory, as evidenced by a sustained rise of urinary pregnanediol-3-glucuronide (PdG) for 10 or more days immediately preceding the onset of menstruation. (thefreedictionary.com)
  • Purpose To inform the design of a larger clinical trial to determine the effectiveness of a new home-based pregnanediol glucuronide (PDG) urine test to confirm ovulation when compared with the standard of serum progesterone. (bmj.com)
  • The DetectX ® Pregnanediol-3-Glucuronide (PDG) Immunoassay kit uses a specifically generated antibody to measure PDG and its metabolites in urine and fecal samples, or in extracted serum and plasma. (arborassays.com)
  • The test strip works by measuring urine for a marker of Progesterone, called pregnanediol-3a-glucuronide (PDG). (clinicaltrials.gov)
  • Pregnanediol-3a-glucuronide (PDG) is the major urine metabolite of Progesterone. (clinicaltrials.gov)
  • Specimens were assayed for estrone-3-glucuronide (E1G) and pregnanediol-3-glucuronide. (aacrjournals.org)
  • An algorithm identifying days of above-baseline E1G that coincided with the days of baseline pregnanediol-3-glucuronide was used to identify days of unopposed estrogen. (aacrjournals.org)
  • This webinar reviews the use and application of an at home urinary test that measures the presence of progesterone in urine (or more specifically tests a urine metabolite of progesterone, pregnanediol 3-glucuronide (PdG), and how this can be used alongside Fertility awareness based methods and may aid some users in increasing the efficacy of Fertility Awareness Based Methods. (iirrm.org)
  • Two immunoassay procedures (radiolabeling and fluorolabeling) were used to measure urine levels of the estrogen metabolite estrone-3-glucuronide and the progesterone metabolite pregnanediol-3-glucuronide. (cdc.gov)
  • The urine samples were analyzed for LH, estrone-3-glucuronide (E13G), and pregnanediol-3-glucuronide (Pd3G). (cdc.gov)
  • First-trimester rapid semiquantitative assay for urine pregnanediol glucuronide predicts gestational. (biomedsearch.com)
  • 2013). Use of urinary pregnanediol 3-glucuronide to confirm ovulation. (onemoresoul.com)
  • Levels of luteinizing hormone, estrone-3-glucuronide (EG), and pregnanediol 3-alpha-glucuronide (PG) will be measured in the urine. (epa.gov)
  • The MCM profile measures estrone-3-glucuronide (E1G), pregnanediol-3-glucuronide (PDG) and luteinizing hormone (LH). (zrtlab.com)
  • Ovulations were determined by measurement of daily urine pregnanediol-3-glucuronide or weekly progesterone levels over 6-9 months of study duration for each participant. (clinicaltrials.gov)
  • Urinary estrone conjugate and pregnanediol 3-glucuronide enzyme immunoassays for population research. (healthtap.com)
  • We assayed urine samples for estrone 3-glucuronide (E13G), pregnanediol 3-glucuronide (Pd3G), and follicle stimulating hormone (FSH). (cdc.gov)
  • Women who reported the highest stress levels had lower levels of two hormones that initiate ovulation, estrone-1-glucuronide and pregnanediol-3-glucuronide. (nih.gov)
  • Urinary pregnanediol 3-glucuronide increased from 18.6 +/- 2.2 to 31.0 +/- 5.7 micro g/mg creatinine (P = 0.038). (omega-research.com)
  • The CA women had shorter luteal phases (P less than 0.05) and lower urinary excretion of pregnanediol glucuronide than the CS women. (nih.gov)
  • In the AA women, urinary estrone glucuronide, pregnanediol glucuronide, and LH excretion were low throughout a 30-day period. (nih.gov)
  • The women wore actigraphic sensors on their wrist to record patterns of activity and rest over 578 sleep episodes and they provided morning urine samples for measurement of concentrations of luteinizing hormone (LH), estrone-3-glucuronide (E1G), and pregnanediol-3-glucuronide (PDG). (eurekalert.org)
  • Over the course of the study, urine was collected daily and measured for estrone 3-glucuronide and pregnanediol 3-glucouronide. (freecme.com)
  • The glucuronide and sulfate conjugates of pregnanediol and progesterone oil 50 mg ml vl are excreted in the bile and urine. (soxanddawgs.com)
  • Estrogen status was based on self-reported menstrual status confirmed by daily evaluation of urinary estrone-1-glucoronide (E1G), pregnanediol glucuronide (PdG), and luteinizing hormone (LH). (galileo-training.com)
  • Pregnanediol (a progesterone metabolite), tetrahydrocorticosterone and tetrahydro compound A (deoxycorticosterone metabolites) were elevated. (mja.com.au)
  • The major metabolites in plasma are the biologically active 20 a-dihydroxyprogesterone and inactive where pregnanediol predominates. (medicinesmexico.com)
  • Most of progesterone and its metabolites, which have reached the systemic circulation, they are excreted by the kidneys, mainly as metabolites glucuroneos pregnanediol and pregnenolone. (medicinesmexico.com)
  • Both serum progesterone levels and the urine concentration of progesterone metabolites ( pregnanediol ) are significantly increased during the latter half of a normal ovulatory cycle. (the-healthcare.org)
  • Retarding renal excretion of pregnanediol. (cadasb.org)
  • Prognostic value of combined assay of total estrogen and pregnanediol in 24 hour urine. (degruyter.com)
  • investigated the glucuronidation of digitoxin in dog liver microsomes and found that several compounds, including testosterone and pregnanediol, were noncompetitive inhibitors. (aspetjournals.org)
  • A test can be done to measure the amount of pregnanediol in urine, which offers an indirect way to measure progesterone levels in the body. (wikipedia.org)
  • Since progesterone levels indicate the functionality of a corpus luteum, and pregnanediol concentration represents 40-45% of the progesterone excreted, estimations of pregnanediol reveal the functionality of a corpus luteum. (wikipedia.org)
  • Their study extracted pregnanediol from pregnancy urine and revealed that pregnanediol concentration in urine indicates the amount of progesterone excreted. (wikipedia.org)
  • Concentrations of a peak with an elution profile similar to that of pregnanediol increased as pregnancy progressed. (biomedsearch.com)
  • The samples were tested to check levels of three hormones linked to the onset of pregnancy - human chorionic gonadotropin (hCG), estrone-3-glucoronide and pregnanediol-3-glucoronide. (themedguru.com)
  • However, pregnanediol concentrations vary with menstrual cycle phases, so it is essential to consider the menstrual cycle phase when examining them. (wikipedia.org)
  • Exposure of zebrafish embryos demonstrated negligible effects of pregnanediol and 17α-hydroxypregnenolone, while mixtures that mimic wastewater and river water composition affected embryo development and led to alteration of steroidogenesis gene transcripts at ng/L concentrations. (viewpoint.fr)
  • Pregnanediol, or 5β-pregnane-3α,20α-diol, is an inactive metabolic product of progesterone. (wikipedia.org)
  • They also demonstrated its close relationship with pregnanediol, a physiologically inactive dihydric alcohol which Butenandt and Marrian had found independently of one another in the urine of pregnant women. (nobelprize.org)
  • A pregnanediol test system is a device intended to measure pregnanediol (a major urinary metabolic product of progesterone) in urine. (fda.gov)
  • Sec. 862.1605 Pregnanediol test system. (fda.gov)
  • Furthermore, current research has demonstrated that pregnanediol concentration in urine is also a measure of ovarian activity. (wikipedia.org)
  • Adverse reactions: Within the initial cancer treatment, recurrent cancer should be reduced to pregnanediol which is otherwise normal. (bigsurlandtrust.org)