Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.
Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.
The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH.
The beginning third of a human PREGNANCY, from the first day of the last normal menstrual period (MENSTRUATION) through the completion of 14 weeks (98 days) of gestation.
An infant during the first month after birth.
Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION).
The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.
A potentially life-threatening condition in which EMBRYO IMPLANTATION occurs outside the cavity of the UTERUS. Most ectopic pregnancies (>96%) occur in the FALLOPIAN TUBES, known as TUBAL PREGNANCY. They can be in other locations, such as UTERINE CERVIX; OVARY; and abdominal cavity (PREGNANCY, ABDOMINAL).
The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.
The last third of a human PREGNANCY, from the beginning of the 29th through the 42nd completed week (197 to 294 days) of gestation.
An infant having a birth weight of 2500 gm. (5.5 lb.) or less but INFANT, VERY LOW BIRTH WEIGHT is available for infants having a birth weight of 1500 grams (3.3 lb.) or less.
The middle third of a human PREGNANCY, from the beginning of the 15th through the 28th completed week (99 to 196 days) of gestation.
The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.
The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.
The state of PREGNANCY in women with DIABETES MELLITUS. This does not include either symptomatic diabetes or GLUCOSE INTOLERANCE induced by pregnancy (DIABETES, GESTATIONAL) which resolves at the end of pregnancy.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
The condition of carrying two or more FETUSES simultaneously.
The event that a FETUS is born dead or stillborn.
The three approximately equal periods of a normal human PREGNANCY. Each trimester is about three months or 13 to 14 weeks in duration depending on the designation of the first day of gestation.
The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
The co-occurrence of pregnancy and NEOPLASMS. The neoplastic disease may precede or follow FERTILIZATION.
Malformations of organs or body parts during development in utero.
Care provided the pregnant woman in order to prevent complications, and decrease the incidence of maternal and prenatal mortality.
The co-occurrence of pregnancy and a blood disease (HEMATOLOGIC DISEASES) which involves BLOOD CELLS or COAGULATION FACTORS. The hematologic disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.
Onset of OBSTETRIC LABOR before term (TERM BIRTH) but usually after the FETUS has become viable. In humans, it occurs sometime during the 29th through 38th week of PREGNANCY. TOCOLYSIS inhibits premature labor and can prevent the BIRTH of premature infants (INFANT, PREMATURE).
Pregnancy in which the mother and/or FETUS are at greater than normal risk of MORBIDITY or MORTALITY. Causes include inadequate PRENATAL CARE, previous obstetrical history (ABORTION, SPONTANEOUS), pre-existing maternal disease, pregnancy-induced disease (GESTATIONAL HYPERTENSION), and MULTIPLE PREGNANCY, as well as advanced maternal age above 35.
The failure of a FETUS to attain its expected FETAL GROWTH at any GESTATIONAL AGE.
Pregnancy in human adolescent females under the age of 19.
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Tests to determine whether or not an individual is pregnant.
The age of the mother in PREGNANCY.
The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.
A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).
Extraction of the FETUS by means of abdominal HYSTEROTOMY.
An infant having a birth weight lower than expected for its gestational age.
Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).
Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage.
Intentional removal of a fetus from the uterus by any of a number of techniques. (POPLINE, 1978)
A condition in pregnant women with elevated systolic (>140 mm Hg) and diastolic (>90 mm Hg) blood pressure on at least two occasions 6 h apart. HYPERTENSION complicates 8-10% of all pregnancies, generally after 20 weeks of gestation. Gestational hypertension can be divided into several broad categories according to the complexity and associated symptoms, such as EDEMA; PROTEINURIA; SEIZURES; abnormalities in BLOOD COAGULATION and liver functions.
The most common (>96%) type of ectopic pregnancy in which the extrauterine EMBRYO IMPLANTATION occurs in the FALLOPIAN TUBE, usually in the ampullary region where FERTILIZATION takes place.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Three or more consecutive spontaneous abortions.
The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.
Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
Pathological processes or abnormal functions of the PLACENTA.
Proteins produced by organs of the mother or the PLACENTA during PREGNANCY. These proteins may be pregnancy-specific (present only during pregnancy) or pregnancy-associated (present during pregnancy or under other conditions such as hormone therapy or certain malignancies.)
The event that a FETUS is born alive with heartbeats or RESPIRATION regardless of GESTATIONAL AGE. Such liveborn is called a newborn infant (INFANT, NEWBORN).
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
An organized and comprehensive program of health care that identifies and reduces a woman's reproductive risks before conception through risk assessment, health promotion, and interventions. Preconception care programs may be designed to include the male partner in providing counseling and educational information in preparation for fatherhood, such as genetic counseling and testing, financial and family planning, etc. This concept is different from PRENATAL CARE, which occurs during pregnancy.
Diminished or absent ability of a female to achieve conception.
A condition of fetal overgrowth leading to a large-for-gestational-age FETUS. It is defined as BIRTH WEIGHT greater than 4,000 grams or above the 90th percentile for population and sex-specific growth curves. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.
The co-occurrence of pregnancy and parasitic diseases. The parasitic infection may precede or follow FERTILIZATION.
The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.
Exposure of the female parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring. It includes pre-conception maternal exposure.
The condition of carrying TWINS simultaneously.
An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).
Delivery of the FETUS and PLACENTA under the care of an obstetrician or a health worker. Obstetric deliveries may involve physical, psychological, medical, or surgical interventions.
Premature separation of the normally implanted PLACENTA from the UTERUS. Signs of varying degree of severity include UTERINE BLEEDING, uterine MUSCLE HYPERTONIA, and FETAL DISTRESS or FETAL DEATH.
Postnatal deaths from BIRTH to 365 days after birth in a given population. Postneonatal mortality represents deaths between 28 days and 365 days after birth (as defined by National Center for Health Statistics). Neonatal mortality represents deaths from birth to 27 days after birth.
The number of pregnancies, complete or incomplete, experienced by a female. It is different from PARITY, which is the number of offspring borne. (From Stedman, 26th ed)
A term used to describe pregnancies that exceed the upper limit of a normal gestational period. In humans, a prolonged pregnancy is defined as one that extends beyond 42 weeks (294 days) after the first day of the last menstrual period (MENSTRUATION), or birth with gestational age of 41 weeks or more.
Clinical and laboratory techniques used to enhance fertility in humans and animals.
Unintended accidental pregnancy, including pregnancy resulting from failed contraceptive measures.
Elements of limited time intervals, contributing to particular results or situations.
A method, developed by Dr. Virginia Apgar, to evaluate a newborn's adjustment to extrauterine life. Five items - heart rate, respiratory effort, muscle tone, reflex irritability, and color - are evaluated 60 seconds after birth and again five minutes later on a scale from 0-2, 0 being the lowest, 2 being normal. The five numbers are added for the Apgar score. A score of 0-3 represents severe distress, 4-7 indicates moderate distress, and a score of 7-10 predicts an absence of difficulty in adjusting to extrauterine life.
The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH.
Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.
The disintegration and assimilation of the dead FETUS in the UTERUS at any stage after the completion of organogenesis which, in humans, is after the 9th week of GESTATION. It does not include embryo resorption (see EMBRYO LOSS).
UTERINE BLEEDING from a GESTATION of less than 20 weeks without any CERVICAL DILATATION. It is characterized by vaginal bleeding, lower back discomfort, or midline pelvic cramping and a risk factor for MISCARRIAGE.
Morphological and physiological development of FETUSES.
Pregnancy, usually accidental, that is not desired by the parent or parents.
Deaths occurring from the 28th week of GESTATION to the 28th day after birth in a given population.
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum.
Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission.
A branch arising from the internal iliac artery in females, that supplies blood to the uterus.
Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.
A condition of abnormally low AMNIOTIC FLUID volume. Principal causes include malformations of fetal URINARY TRACT; FETAL GROWTH RETARDATION; GESTATIONAL HYPERTENSION; nicotine poisoning; and PROLONGED PREGNANCY.
Abortion induced to save the life or health of a pregnant woman. (From Dorland, 28th ed)
Selective abortion of one or more embryos or fetuses in a multiple gestation pregnancy. The usual goal is to improve the outcome for the remaining embryos or fetuses.
Two individuals derived from two FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother. Twins are either monozygotic (TWINS, MONOZYGOTIC) or dizygotic (TWINS, DIZYGOTIC).
Transfer of preovulatory oocytes from donor to a suitable host. Oocytes are collected, fertilized in vitro, and transferred to a host that can be human or animal.
The capacity to conceive or to induce conception. It may refer to either the male or female.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth.
Organized efforts by communities or organizations to improve the health and well-being of the mother.
Medical problems associated with OBSTETRIC LABOR, such as BREECH PRESENTATION; PREMATURE OBSTETRIC LABOR; HEMORRHAGE; or others. These complications can affect the well-being of the mother, the FETUS, or both.
Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA).
Artificial introduction of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.
Spontaneous tearing of the membranes surrounding the FETUS any time before the onset of OBSTETRIC LABOR. Preterm PROM is membrane rupture before 37 weeks of GESTATION.
Methods pertaining to the generation of new individuals, including techniques used in selective BREEDING, cloning (CLONING, ORGANISM), and assisted reproduction (REPRODUCTIVE TECHNIQUES, ASSISTED).
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
A human infant born before 37 weeks of GESTATION.
The repetitive uterine contraction during childbirth which is associated with the progressive dilation of the uterine cervix (CERVIX UTERI). Successful labor results in the expulsion of the FETUS and PLACENTA. Obstetric labor can be spontaneous or induced (LABOR, INDUCED).
A type of ectopic pregnancy in which the EMBRYO, MAMMALIAN implants in the ABDOMINAL CAVITY instead of in the ENDOMETRIUM of the UTERUS.
The circulation of BLOOD, of both the mother and the FETUS, through the PLACENTA.
Nutrition of a mother which affects the health of the FETUS and INFANT as well as herself.
A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS).
Physiological mechanisms that sustain the state of PREGNANCY.
Maternal deaths resulting from complications of pregnancy and childbirth in a given population.
The mucous membrane lining of the uterine cavity that is hormonally responsive during the MENSTRUAL CYCLE and PREGNANCY. The endometrium undergoes cyclic changes that characterize MENSTRUATION. After successful FERTILIZATION, it serves to sustain the developing embryo.
A federal area located between Maryland and Virginia on the Potomac river; it is coextensive with Washington, D.C., which is the capital of the United States.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Morphological and physiological development of EMBRYOS or FETUSES.
Time interval, or number of non-contraceptive menstrual cycles that it takes for a couple to conceive.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
A condition of abnormally high AMNIOTIC FLUID volume, such as greater than 2,000 ml in the LAST TRIMESTER and usually diagnosed by ultrasonographic criteria (AMNIOTIC FLUID INDEX). It is associated with maternal DIABETES MELLITUS; MULTIPLE PREGNANCY; CHROMOSOMAL DISORDERS; and congenital abnormalities.
Evaluation procedures that focus on both the outcome or status (OUTCOMES ASSESSMENT) of the patient at the end of an episode of care - presence of symptoms, level of activity, and mortality; and the process (ASSESSMENT, PROCESS) - what is done for the patient diagnostically and therapeutically.
Human females who are pregnant, as cultural, psychological, or sociological entities.
Onset of HYPERREFLEXIA; SEIZURES; or COMA in a previously diagnosed pre-eclamptic patient (PRE-ECLAMPSIA).
Official certifications by a physician recording the individual's birth date, place of birth, parentage and other required identifying data which are filed with the local registrar of vital statistics.
Social and economic factors that characterize the individual or group within the social structure.
The number of births in a given population per year or other unit of time.
Bleeding from blood vessels in the UTERUS, sometimes manifested as vaginal bleeding.
Female parents, human or animal.
Diseases involving the FALLOPIAN TUBES including neoplasms (FALLOPIAN TUBE NEOPLASMS); SALPINGITIS; tubo-ovarian abscess; and blockage.
Inhaling and exhaling the smoke of burning TOBACCO.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
The hormone-responsive glandular layer of ENDOMETRIUM that sloughs off at each menstrual flow (decidua menstrualis) or at the termination of pregnancy. During pregnancy, the thickest part of the decidua forms the maternal portion of the PLACENTA, thus named decidua placentalis. The thin portion of the decidua covering the rest of the embryo is the decidua capsularis.
Nutrition of FEMALE during PREGNANCY.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Male parents, human or animal.
The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.
In utero measurement corresponding to the sitting height (crown to rump) of the fetus. Length is considered a more accurate criterion of the age of the fetus than is the weight. The average crown-rump length of the fetus at term is 36 cm. (From Williams Obstetrics, 18th ed, p91)
Termination of pregnancy under conditions allowed under local laws. (POPLINE Thesaurus, 1991)
Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
Increase in BODY WEIGHT over existing weight.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
Physiologic or biochemical monitoring of the fetus. It is usually done during LABOR, OBSTETRIC and may be performed in conjunction with the monitoring of uterine activity. It may also be performed prenatally as when the mother is undergoing surgery.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
The development of the PLACENTA, a highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products between mother and FETUS. The process begins at FERTILIZATION, through the development of CYTOTROPHOBLASTS and SYNCYTIOTROPHOBLASTS, the formation of CHORIONIC VILLI, to the progressive increase in BLOOD VESSELS to support the growing fetus.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Percutaneous transabdominal puncture of the uterus during pregnancy to obtain amniotic fluid. It is commonly used for fetal karyotype determination in order to diagnose abnormal fetal conditions.
The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The transmission of infectious disease or pathogens from one generation to another. It includes transmission in utero or intrapartum by exposure to blood and secretions, and postpartum exposure via breastfeeding.
Any drug treatment modality designed to inhibit UTERINE CONTRACTION. It is used in pregnant women to arrest PREMATURE LABOR.
Exposure of the male parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
The lengths of intervals between births to women in the population.
The fusion of a spermatozoon (SPERMATOZOA) with an OVUM thus resulting in the formation of a ZYGOTE.
Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.
Surgery performed on the pregnant woman for conditions associated with pregnancy, labor, or the puerperium. It does not include surgery of the newborn infant.
Tumors or cancer of the UTERUS.
Methanes substituted with three halogen atoms, which may be the same or different.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
Polymicrobial, nonspecific vaginitis associated with positive cultures of Gardnerella vaginalis and other anaerobic organisms and a decrease in lactobacilli. It remains unclear whether the initial pathogenic event is caused by the growth of anaerobes or a primary decrease in lactobacilli.
The care of women and a fetus or newborn given before, during, and after delivery from the 28th week of gestation through the 7th day after delivery.
Specialized arterial vessels in the umbilical cord. They carry waste and deoxygenated blood from the FETUS to the mother via the PLACENTA. In humans, there are usually two umbilical arteries but sometimes one.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN.
A prenatal ultrasonography measurement of the soft tissue behind the fetal neck. Either the translucent area below the skin in the back of the fetal neck (nuchal translucency) or the distance between occipital bone to the outer skin line (nuchal fold) is measured.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
Artificially induced UTERINE CONTRACTION. Generally, LABOR, OBSTETRIC is induced with the intent to cause delivery of the fetus and termination of pregnancy.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Extraction of the fetus by means of obstetrical instruments.
A demographic parameter indicating a person's status with respect to marriage, divorce, widowhood, singleness, etc.
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
State of the body in relation to the consumption and utilization of nutrients.
Persons living in the United States having origins in any of the black groups of Africa.
Compounds which increase the capacity to conceive in females.
Organized services to provide health care to expectant and nursing mothers.
A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.
A nonreassuring fetal status (NRFS) indicating that the FETUS is compromised (American College of Obstetricians and Gynecologists 1988). It can be identified by sub-optimal values in FETAL HEART RATE; oxygenation of FETAL BLOOD; and other parameters.
The threadlike, vascular projections of the chorion. Chorionic villi may be free or embedded within the DECIDUA forming the site for exchange of substances between fetal and maternal blood (PLACENTA).
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
The part of a human or animal body connecting the HEAD to the rest of the body.
A post-MORULA preimplantation mammalian embryo that develops from a 32-cell stage into a fluid-filled hollow ball of over a hundred cells. A blastocyst has two distinctive tissues. The outer layer of trophoblasts gives rise to extra-embryonic tissues. The inner cell mass gives rise to the embryonic disc and eventual embryo proper.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Early pregnancy loss during the EMBRYO, MAMMALIAN stage of development. In the human, this period comprises the second through eighth week after fertilization.
The return of a sign, symptom, or disease after a remission.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Essential dietary elements or organic compounds that are required in only small quantities for normal physiologic processes to occur.
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
Procedures to obtain viable OOCYTES from the host. Oocytes most often are collected by needle aspiration from OVARIAN FOLLICLES before OVULATION.
Failure of the PLACENTA to deliver an adequate supply of nutrients and OXYGEN to the FETUS.
Incompetent UTERINE CERVIX is usually diagnosed in the second trimester of PREGNANCY. It is characterized by passive painless cervical dilation in the absence of UTERINE CONTRACTION; BLEEDING; INFECTION; and sometimes with the amniotic sac (AMNIOTIC MEMBRANE) bulging through the partially dilated cervix. Left untreated, this condition may lead to premature pregnancy loss, such as HABITUAL ABORTION.

Obstetric and neonatal outcome following chronic hypertension in pregnancy among different ethnic groups. (1/5648)

We retrospectively studied pre-eclampsia rate and obstetric outcome in a cohort of 436 pregnancies amongst 318 women of different ethnic backgrounds attending an antenatal hypertension clinic from 1980-1997, identifying 152 women (213 pregnancies) with chronic essential hypertension. The ethnic breakdown was: White, 64 (30.0%) pregnancies in 48 (31.5%) women; Black/Afro-Caribbean, 79 (37.1%) pregnancies in 56 (36.8%) women; and Indo-Asians, 70 (32.3%) pregnancies in 48 (31.6%) women. The prevalences of pre-eclampsia in White, Black and Indo-Asian women were 17.2%, 12.7% and 18.6%, respectively (p = 0.58). Pregnancies of Indo-Asian women were of shorter gestation, and babies in this group also had lower birth weight and ponderal index compared to those of White and Black women (all p < 0.05). The proportions of overall perinatal mortality were 1.6% for Whites (1/64), 3.8% for Blacks (3/79) and 10.0% for Indo-Asians (7/70), suggesting increased risk in the Indo-Asian group. Indo-Asian women with chronic essential hypertension need careful antenatal care and observation during pregnancy.  (+info)

Endocrine biomarkers of early fetal loss in cynomolgus macaques (Macaca fascicularis) following exposure to dioxin. (2/5648)

This study examines the endocrine alterations associated with early fetal loss (EFL) induced by an environmental toxin, TCDD (2,3,7, 8-tetrachlorodibenzo-p-dioxin), in the cynomolgus macaque, a well-documented reproductive/developmental model for humans. Females were administered single doses of 1, 2, and 4 microgram/kg TCDD (n = 4 per dose group) on gestational day (GD) 12. Urinary estrogen metabolites (estrone conjugates) were monitored to establish the day of ovulation, and serum hormones (estradiol, progesterone, chorionic gonadotropin, relaxin) were measured to assess ovarian and placental endocrine status before and after treatment. EFL occurred between GDs 22 and 32 in 10 of the 12 animals treated with TCDD. The primary endocrine alterations associated with TCDD treatment were significant decreases in serum estradiol and bioactive chorionic gonadotropin concentrations (p < 0.02). Less pronounced decreases in serum progesterone (p = 0.10) and relaxin (p < 0.08) also followed TCDD treatment. In contrast, immunoreactive chorionic gonadotropin concentrations were not reduced by TCDD exposure at any level, indicating that TCDD targets specific components of the chorionic gonadotropin synthesis machinery within the trophoblast to alter the functional capacity of the hormone. These data demonstrate the value of endocrine biomarkers in identifying a toxic exposure to primate pregnancy many days before direct signs of reproductive toxicity were apparent. The increased EFL that occurred after exposure to TCDD might reflect a toxic response initially mediated via endocrine imbalance, leading to placental insufficiency, compromised embryonic circulation, and subsequent EFL.  (+info)

Outcome of pregnancy in women with congenital shunt lesions. (3/5648)

OBJECTIVE: To evaluate the outcome of pregnancy in women with congenital shunt lesions. SETTING: Retrospective study in a tertiary care centre. METHODS: Pregnancy history was obtained by a standardised questionnaire and medical records were reviewed. PATIENTS: 175 women were identified, at a mean (SD) age of 42 (14) years. Pregnancies occurred in 126 women: 50 with an atrial septal defect, 22 with a ventricular septal defect, 22 with an atrioventricular septal defect, 19 with tetralogy of Fallot, and 13 with other complex shunt lesions. RESULTS: 309 pregnancies were reported by 126 woman (2.5 (1.6) pregnancies per woman). The shortening fraction of the systemic ventricle was 40 (8)%, and 98% were in New York Heart Association class I-II at last follow up. Spontaneous abortions occurred in 17% of pregnancies (abortion rate, 0.4 (0.9) per woman). Gestational age of the 241 newborn infants was 8.8 (0.8) months. There were no maternal deaths related to pregnancy. Pre-eclampsia and embolic events were observed in 1.3% and 0.6%, respectively of all pregnancies. Women with complex shunt lesions more often underwent caesarean section (70% v 15-30%, p = 0.005) and gave birth to smaller babies for equivalent gestation (2577 (671) g v 3016 (572) to 3207 (610) g, p < 0.05). The recurrence risk of congenital heart disease was 2.5%. CONCLUSIONS: The outcome of pregnancy is favourable in women with congenital shunt lesions if their functional class and their systolic ventricular function are good. Such patients can be reassured.  (+info)

Pregnancy after atrial repair for transposition of the great arteries. (4/5648)

OBJECTIVE: To investigate the risk of pregnancy in patients with transposition of the great arteries (TGA) who have undergone atrial repair. DESIGN: Retrospective analysis (1962-94) of 342 TGA patients who underwent atrial repair. Of 231 known late survivors, 48 were women over 18 years old who were interviewed about possible reproductive plans and previous pregnancies. As a control, comparison was made with data of 57 500 women (mean age 26 years) obtained from the Swiss Statistical Bank in Bern. RESULTS: Mean follow up was 13.7 years; 66% remained asymptomatic, 29% had mild to moderate cardiac symptoms, and 5% suffered from severe cardiac symptoms (New York Heart Association grade III-IV). Thirty six of the 48 women wished to bear children and, to date, there have been 10 live births, two spontaneous first trimester abortions, and one induced abortion at 16 weeks. During pregnancy there was one case of cardiac deterioration and two cases of pneumonia. There was no evidence of congenital heart disease in the children. CONCLUSIONS: In this relatively small series the completion of pregnancy in women with TGA who had undergone atrial repair and who had normal functional cardiac status was uncomplicated  (+info)

Effect of the interval between pregnancies on perinatal outcomes. (5/5648)

BACKGROUND: A short interval between pregnancies has been associated with adverse perinatal outcomes. Whether that association is due to confounding by other risk factors, such as maternal age, socioeconomic status, and reproductive history, is unknown. METHODS: We evaluated the interpregnancy interval in relation to low birth weight, preterm birth, and small size for gestational age by analyzing data from the birth certificates of 173,205 singleton infants born alive to multiparous mothers in Utah from 1989 to 1996. RESULTS: Infants conceived 18 to 23 months after a previous live birth had the lowest risks of adverse perinatal outcomes; shorter and longer interpregnancy intervals were associated with higher risks. These associations persisted when the data were stratified according to and controlled for 16 biologic, sociodemographic, and behavioral risk factors. As compared with infants conceived 18 to 23 months after a live birth, infants conceived less than 6 months after a live birth had odds ratios of 1.4 (95 percent confidence interval, 1.3 to 1.6) for low birth weight, 1.4 (95 percent confidence interval, 1.3 to 1.5) for preterm birth, and 1.3 (95 percent confidence interval, 1.2 to 1.4) for small size for gestational age; infants conceived 120 months or more after a live birth had odds ratios of 2.0 (95 percent confidence interval, 1.7 to 2.4);1.5 (95 percent confidence interval, 1.3 to 1.7), and 1.8 (95 percent confidence interval, 1.6 to 2.0) for these three adverse outcomes, respectively, when we controlled for all 16 risk factors with logistic regression. CONCLUSIONS: The optimal interpregnancy interval for preventing adverse perinatal outcomes is 18 to 23 months.  (+info)

Fetal growth rate and adverse perinatal events. (6/5648)

OBJECTIVE: To study fetal weight gain and its association with adverse perinatal events in a serially scanned high-risk population. SUBJECTS AND METHODS: A total of 200 pregnant women considered at increased risk of uteroplacental insufficiency had a total of 1140 scans in the third trimester, with a median of six scans in each pregnancy. The average fetal growth rate was retrospectively calculated for the last 6 weeks to birth, and expressed as daily weight gain in grams per day. Adverse pregnancy outcome was defined as operative delivery for fetal distress, acidotic umbilical artery pH (< 7.15), or admission to the neonatal intensive care unit (NICU). RESULTS: Fetuses with normal outcome in this high-risk pregnancy population had an average antenatal growth rate of 24.2 g/day. Compared to pregnancies with normal outcome, the growth rate was slower in those that required operative delivery for fetal distress (20.9 g/day, p < 0.05) and those that required admission to the NICU (20.3 g/day, p < 0.05). The growth rate in pregnancies resulting in acidotic umbilical artery pH also seemed lower, but this did not reach statistical significance. CONCLUSIONS: Impaired fetal weight gain prior to birth is associated with adverse perinatal events suggestive of growth failure.  (+info)

Serum progesterone in predicting pregnancy outcome after assisted reproductive technology. (7/5648)

PURPOSE: Our purpose was to determine whether serum progesterone predicts pregnancy outcome after superovulation. METHODS: One hundred twenty-three consecutively pregnant patients were divided into three groups: group I, 55 patients following superovulation for assisted reproductive technologies; group II, 23 patients after correction of oligoovulation; and group III, 45 patients who conceived spontaneously. When beta-human chorionic gonadotropin was positive, progesterone was measured on the same serum sample. A serum progesterone level of 45 microns/L was set to differentiate between nonviable pregnancy and ongoing pregnancy. RESULTS: In group I, zero (0%) of 38 ongoing pregnancies and 10 (59%) of 17 nonviable pregnancies were observed with a progesterone level of < 45 microns/L [14.2 ng/ml (P < 0.001)]. In group II, 4 (27%) of 15 ongoing pregnancies and 5 (63%) of 8 nonviable pregnancies had a progesterone level of < 45 microns/L (P = NS). In group III, 10 (42%) of 24 ongoing pregnancies and 15 (71%) of 21 nonviable pregnancies were observed with a progesterone level of < 45 microns/L (14.2 ng/ml) (P = NS). CONCLUSIONS: A serum progesterone level of < 45 nM predicts nonviable pregnancy after superovulation for assisted reproductive technology.  (+info)

Autologous endometrial co-culture in patients with repeated failures of implantation after in vitro fertilization-embryo transfer. (8/5648)

PURPOSE: Our purpose was to evaluate the effect of coculture on preembryo development and clinical outcome. METHODS: Enrolled patients underwent a luteal-phase endometrial biopsy. The tissue was then enzymatically digested (collagenase) and the stromal and glandular cells were separated by differential sedimentation rates. These cells were cultured to confluence, released, and then cryopreserved until the patient's in vitro fertilization (IVF)-embryo transfer (ET) cycle. All normally fertilized oocytes were then placed on the co-cultured cells until transfer on day 3. Preembryo development on co-culture was compared to that in the patient's noncocultured previous cycle. Implantation and clinical pregnancy rates were compared to those in a control group of patients undergoing IVF during the study period who were matched for age, stimulation protocol, number of oocytes retrieved, and preembryos transferred. RESULTS: Twenty-nine women underwent 31 cycles of IVF-ET. On day 3 the overall mean number of blastomeres per preembryo on co-culture compared to that in the patient's previous cycle was 6.3 +/- 1.8 vs. 5.6 +/- 1.2 (P = 0.04). The average percentage of cytoplasmic fragments on co-culture compared to the previous cycle was 16 +/- 9% vs. 19 +/- 9% (P = 0.32). At transfer, after preembryo selection, the mean number of blastomeres per preembryo on co-culture compared to that in the patient's previous cycle was 6.8 +/- 1.6 vs. 6.6 +/- 1.3 (P = 0.5). The implantation and clinical pregnancy rates between co-culture and the matched control group were 15% (14/93) vs. 13% (16/124) (P = 0.79) and 29% (9/31) vs. 25% (10/40) (P = 0.45). CONCLUSIONS: There was a significant improvement in the average number of blastomeres per preembryo on co-culture compared to that in the patient's previous noncoculture cycle. The overall implantation and clinical pregnancy rates between co-culture and a matched control group were not significantly different.  (+info)

Background/Purpose: Autoimmune conditions are associated with an increased risk of adverse pregnancy complications and outcomes, suggesting that pregnancy complications may mediate the excess risk. We performed a causal mediation analysis to quantify the mediated effects of autoimmune conditions on adverse pregnancy outcomes.. Methods: We queried a retrospective California birth cohort created from linked birth certificates and hospital discharge summaries. From 2,963,888 births, we identified women with rheumatoid arthritis, systemic lupus erythematosus, psoriasis and inflammatory bowel disease. Pregnancy complications included preeclampsia/hypertension, gestational diabetes and infection in pregnancy. Adverse pregnancy outcomes were preterm birth, cesarean delivery and small for gestational age. We performed a causal mediation analysis to estimate the total effects of each autoimmune condition and adverse pregnancy outcome, and the indirect effects of each pregnancy complication.. Results: ...
How to Cite: Tennakoon, V., Weerasekera, D.S. and Yasawardene, S.G., 2012. Successful pregnancy outcomes following in-vitro fertilization in infertile couples with high levels of antisperm antibodies. Sri Lanka Journal of Obstetrics and Gynaecology, 32(2), pp.47-48. DOI: ...
To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality ...
|jats:p||jats:italic|Objectives|/jats:italic|. Hepatitis B virus (HBV) was believed to have minimal impact on pregnancy outcomes apart from the risk of perinatal transmission. In more recent years, there have been reports of adverse associations, most consistently preterm birth (PTB), but this is in the context of high rates of caesarean section. The aim of this study was to explore the association of HBV on pregnancy outcomes in marginalized, low-income populations on the Myanmar-Thailand border.|jats:italic| Methods|/jats:italic|. HBsAg positive (+) point of care rapid detection tests results were confirmed by immunoassays. Women with a confirmed HBsAg status, HIV- and syphilis-negative at first antenatal care screening, singleton fetus and known pregnancy outcome (Aug-2012 to Dec-2016) were included. Logistic regression analysis was used to evaluate associations between HBV group (controls HBsAg negative, HBsAg+/HBeAg-, or HBsAg+/HBeAg+) and pregnancy outcome and comorbidity.|jats:italic| Results|
The purpose of this study was to compare pregnancy outcomes for teenagers who received prenatal care at a teen-only health clinic versus pregnancy outcomes for teenagers who received prenatal care at a traditional obstetrical/gynecological clinic. In addition, this study explored the relationship between maternal demographic characteristics and pregnancy outcomes. Data were collected through retrospective chart reviews for a total sample of 60 cases (30 from the teen-only clinic and 30 from the traditional clinic). Inclusion criteria were 1) female who was between the age of 1 0 and 19 years when she presented for prenatal care, 2) at least 8 weeks post-partum at the time of the study, 3) prenatal records available in the chart, and 4) delivery record available in the chart. Data on pregnancy outcomes included maternal total weight gain, maternal body mass index, number of weeks at start of prenatal care, number of prenatal appointments attended, post-partum appointment attendance, ...
Although the general statistical advice is to keep continuous exposure variables as continuous in statistical analyses, categorisation is still a common approach in medical research. In a recent paper from the Hyperglycaemia and Adverse Pregnancy Outcome (HAPO) Study, categorisation of body mass index (BMI) was used when analysing the effect of BMI on adverse pregnancy outcomes. The lowest category, labelled underweight, was used as the reference category. The present paper gives a summary of reasons for categorisation and methodological drawbacks of this approach. We also discuss the choice of reference category and alternative analyses. We exemplify our arguments by a reanalysis of results from the HAPO paper. Categorisation of continuous exposure data results in loss of power and other methodological challenges. An unfortunate choice of reference category can give additional lack of precision and obscure the interpretation of risk estimates. A highlighted odds ratio (OR) in the HAPO study is the OR
TY - JOUR. T1 - A description of the methods of the Nulliparous Pregnancy Outcomes Study. T2 - Monitoring mothers-to-be (nuMoM2b). AU - Haas, David. AU - Parker, Corette B.. AU - Wing, Deborah A.. AU - Parry, Samuel. AU - Grobman, William A.. AU - Mercer, Brian M.. AU - Simhan, Hyagriv N.. AU - Hoffman, Matthew K.. AU - Silver, Robert M.. AU - Wadhwa, Pathik. AU - Iams, Jay D.. AU - Koch, Matthew A.. AU - Caritis, Steve N.. AU - Wapner, Ronald J.. AU - Esplin, M. Sean. AU - Elovitz, Michal A.. AU - Foroud, Tatiana. AU - Peaceman, Alan M.. AU - Saade, George R.. AU - Willinger, Marian. AU - Reddy, Uma M.. PY - 2015/4/1. Y1 - 2015/4/1. N2 - Objective The primary aim of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be is to determine maternal characteristics, which include genetic, physiologic response to pregnancy, and environmental factors that predict adverse pregnancy outcomes. Study Design Nulliparous women in the first trimester of pregnancy were recruited into an ...
There are two very common concerns for couples that are considering in vitro fertilization: Unhealthy embryos result in failed pregnancies, which can lead to frustration, extra cost and even depression for IVF couples and multiple embryo transplants increase the risk of complications for both mother and baby. With more and more couples seeking out the assistance of in vitro fertilization to achieve pregnancy, researchers have been looking for more ways to help improve the outcomes of those pregnancies. A new technology known as Eeva (Early Embryo Viability Assessment) may soon help with both of these concerns.. The new technology, shared by a team of investigators at the Pacific Fertility Center (USA) and at the Hewitt Fertility Center in Liverpool (UK) at Fertility 2013, will hopefully result in more favorable pregnancy outcomes and reduce the requirement to move more than one embryo at a time into the womb. This would reduce the number of multiple pregnancies, which have been cited as one of ...
The haemodynamic changes of pregnancy can have a negative impact on maternal cardiac health, especially in women with pre-existing cardiac disease. In the most recent Confidential Inquiries into Maternal Mortality in the United Kingdom, heart disease was found to be the most common indirect cause of maternal death during pregnancy.1 Pregnancy counselling and management for women with heart disease is being increasingly recognized as an important aspect of their overall cardiac care. With increasing awareness, there has been a growing body of research focused on pregnancy outcomes and risk stratification. There have also been new initiatives to improve clinical care, such as the 2011 European Society of Cardiology (ESC) guidelines on the management of cardiovascular disease during pregnancy.2 While our current understanding of pregnancy risk assessment and management has improved over the past 20 years, many questions can only be answered by collaborative efforts. ...
Objective: To test the hypothesis that women screened for psychosocial factors, including partner abuse, as recommended by the American College of Obstetricians and Gynecologists would have higher neonatal birth weight, longer gestational age at delivery, higher Apgar scores, and fewer maternal complications. Methods: We evaluated a universal psychosocial screening intervention using a retrospective cohort (n=881 prenatal care patients). Pregnancy outcomes among patients screened beginning in 2008 (n=464) were compared with outcomes among women receiving care before universal screening was implemented (n=417). Data were obtained from medical records between 2007 and 2009. Multivariable logistic regression and analysis of covariance were used to estimate the association between screening and pregnancy outcomes among singleton births adjusting for confounders (prior preterm births, insurance, and mode of delivery). Results: Screened women were less likely than women not universally screened to have low
Results: There was a statistically significant association between exposure to physical violence during pregnancy and preterm birth (PTB) or low birth weight (LBW). After adjustment for age, education, occupation, body mass index (BMI), haemoglobin level, previous adverse pregnancy outcomes, the pregnant women who were exposed to physical violence during pregnancy were five times more likely to have PTB (AOR = 5.5; 95%CI: 2.1-14.1) and were nearly six times more likely to give birth to a child of LBW (AOR = 5.7; 95%CI: 2.2-14.9) as compared to those who were not exposed to physical violence ...
The existing research on pregnancy outcomes for women with intellectual and developmental disabilities (IDD) is sparse. This study analyzed the 2010 Healthcare Cost and Utilization Project Nationwide Inpatient Sample and compared deliveries among women with IDD (n = 340) to the general obstetric population. Women with IDD had longer hospital stays and were more likely to have Caesarean deliveries in contrast to other women. Rates of adverse pregnancy outcomes were elevated for women with IDD across a range of measures, including early labor, preterm birth, and preeclampsia, and their infants were more likely to have low birth weight, even after adjusting for age, race, ethnicity, and insurance type. Targeted interventions are needed to address these deleterious outcomes.
Abstract Background: Household air pollution (HAP) exposure has been linked to adverse pregnancy outcomes. Objectives: A randomized controlled trial was undertaken in Ibadan, Nigeria to determine the impact of cooking with ethanol on pregnancy outcomes. Methods: Three-hundred-twenty-four pregnant women were randomized to either the control (continued cooking using kerosene/firewood stove, n = 162) or intervention group (received ethanol stove, n = 162). Primary outcome variables were birthweight, preterm delivery, intrauterine growth restriction (IUGR), and occurrence of miscarriage/stillbirth. Results: Mean birthweights for ethanol and controls were 3076 and 2988 g, respectively; the difference, 88 g, (95% confidence interval: − 18 g to 194 g), was not statistically significant (p = 0.10). After adjusting for covariates, the difference reached significance (p = 0.020). Rates of preterm delivery were 6.7% (ethanol) and 11.0% (control), (p = 0.22). Number of miscarriages was 1(ethanol) vs. 4 ...
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Pregnancy as a Window to Future Cardiovascular Health: Adverse Pregnancy Outcomes as Predictors of Increased Risk Factors for Cardiovascular Disease (U10) NOT-HL-12-154. NHLBI
Adverse pregnancy outcomes (APOs)-including pre-term birth, pre-eclampsia, and intrauterine growth restriction-are common interrelated disorders caused by placental dysfunction and maternal vascular abnormalities (endothelial activation, inflammation, and vasospasm) that occur in approximately 10% to 20% of pregnancies. Women who experience APOs are at increased risk for future cardiovascular disease (CVD). APOs are associated with increased risk of development of hypertension, left ventricular hypertrophy/dysfunction, vascular dysfunction, and renal dysfunction. The vascular abnormalities that are present during an APO also underlie common, difficult-to-treat forms of CVD in women as they age (e.g., cardiac microvascular dysfunction, heart failure with preserved ejection fraction), suggesting shared mechanistic pathways for APOs and CVD. Here, the authors synthesize the current information and knowledge gaps regarding the progression from APO to CVD. Understanding the risk factors for and ...
Inkster , M E , Fahey , T P , Donnan , P T , Leese , G P , Mires , G J & Murphy , D J 2006 , Poor glycated haemoglobin control and adverse pregnancy outcomes in type 1 and type 2 diabetes mellitus : systematic review of observational studies , BMC Pregnancy and Childbirth , vol. 6 , 30 . ...
Comparison of adverse pregnancy outcome between teenage and adult women at a tertiary hospital in South Africa., ME Hoque, OA Towobola, TJ Mashamba, T Mono
In this study, women with AS showed higher risk for CS than those without AS, but other maternal and foetal outcomes were comparable, including LBW, after adjusting for the number of foetuses.. The results of the present study are in line with the aforementioned studies of AS and pregnancy. The previous retrospective case-control study with 20 pregnant women with AS demonstrated that pregnancy outcome of patients with AS was not different from that of healthy control subjects, except for older maternal age and higher rate of female foetuses in women with AS [17]. In addition, in the retrospective study involving 12 pregnant women with AS, pregnancy outcome was not significantly affected by the disease [18]. Similarly, a retrospective study including a cohort of 939 patients from the AS International Federation Societies in USA, Canada and Europe showed favourable pregnancy and neonatal outcomes in women with AS [19]. However, a recent nationwide population-based case-control study in Sweden was ...
Childcare providers are overwhelmingly women of childbearing age. Occupational risks in this sector include exposure to biological (infectious) or physical (standing, carrying loads) hazards, many of which are associated with adverse pregnancy outcomes such as children with congenital...
Introduction: Although numerous studies have depicted the association between adverse pregnancy outcomes and the future fertility status, this relationship has not b...
This study aims at investigating the effects of maternal depressive symptomatology on pregnancy outcomes and newborn development. How paternal psychopathology is involved in the association will also be explored. This is a three-year prospective cohort study. Three versions of questionnaires (the mother, the father, and the infant) will be developed first. For parents, data on self-reported symptomatology such as depression, anxiety, and stress will be collected, while for infants, maternal report on newborn development will be measured. Then, two medical centers and two regional hospitals will be selected. All pregnant women who undergo a first-trimester prenatal visit, who plan to carry the baby till term, and whose spouse is also willing to participate will be invited to join our study. We expect to recruit a total of 194 pairs of depressive mothers and her spouses and 278 pairs of non-depressive mothers and her spouses in our study. After the informed consent is obtained, one baseline ...
Periodontitis and Adverse Pregnancy Outcomes Oral Health and General Health - What are the Connections? Continuing Education Course
Despite large numbers of asylum seekers, there is a lack of evidence on pregnancy outcomes and obstetric care of asylum seeking women in Germany. Cross-sectional study (2010-2016) using administrative data of the main referral hospital for pregnant asylum seekers of the reception center of a large federal state in South Germany. Inclusion criteria: women aged 12-50 years, admitted in relation to pregnancy, childbirth or post-partum complications. Outcomes: differences between asylum seekers and residents in the prevalence of high-risk pregnancy conditions, abortive outcomes/stillbirths, peri- and postnatal maternal complications, neonatal complications, and caesarean sections. Analysis: odds ratios (OR) and 95% confidence intervals (CI) obtained by single and multiple logistic regression analysis. Attributable fractions among the exposed (Afe) and among the total population (Afp) were calculated for selected outcomes. Of 19,864 women admitted in relation to pregnancy, childbirth or post-partum
The study showed that the risk of premature birth, microcephaly, and hyperemesis was higher for women with ED of any type. Any form of ED increased the risk of premature delivery with the highest risk for women with anorexia nervosa (60%), followed by unspecified ED (40%) and bulimia (40%). The risk of very preterm birth was highest in bulimia, at 70%, but all three subtypes had a 70% to 90% increased risk of induced preterm birth for medical reasons rather than spontaneous preterm birth ...
Atul Kumar Singh, Anurag Srivastava, M Dabral, SB Gupta.Assessment of the effect of Antenatal checkups and IFA supplementation on pregnancy outcome.NATIONAL JOURNAL OF MEDICAL AND ALLIED SCIENCES 2012;1(1):6-10 ...
TY - JOUR. T1 - Clustering of U.S. women receiving no prenatal care. T2 - Differences in pregnancy outcomes and implications for targeting interventions. AU - Taylor, Cathy R.. AU - Alexander, Greg R.. AU - Hepworth, Joseph T.. PY - 2005/6/1. Y1 - 2005/6/1. N2 - Objectives: Prenatal care is an established mechanism for identifying and managing risk factors impacting pregnancy outcomes. Despite aggressive efforts in the United States (US) to assure that all women begin care in the first trimester, every year about 70,000 women in the US receive no care prior to delivery. We hypothesized that US women receiving no prenatal care comprise clusters (subgroups) with distinctive behavioral, socio-demographic, and medical risks and that birth outcomes differ among the clusters. Methods: White, Black, and Hispanic women (n= 126,220) receiving no prenatal care and delivering a live, singleton infant were identified from linked birth and death certificates for years 1995 through 1997. Cluster analysis was ...
HSS releases study findings regarding women with lupus and good pregnancy outcomes., Pioneering Study Finds Most Women with Lupus can Have Good Pregnancy Outcomes, Identifies Risk Factors Linked to Poor Outcomes
Promising research led by investigators at Hospital for Special Surgery may offer hope for women with lupus who once thought that pregnancy was too risky.
Many studies have investigated factors, often in relative isolation from confounders, and usually in association with adverse pregnancy outcome. We are not aware of any studies using a similar approach to that employed in the present study. Previous evidence of an association between a factor and adverse outcome cannot be extrapolated to indicate that the same variable reduces the likelihood of an uncomplicated pregnancy, but it may support biological plausibility. For example, (lower) maternal age was not included in the final list of variables associated with uncomplicated pregnancy in our study, despite many studies linking advanced maternal age to adverse pregnancy outcomes.14 15 Although it might seem intuitive that improvable factors related to diet, blood pressure, heart rate, weight, and smoking would predict uncomplicated pregnancy, the evidence from well conducted prospective cohort studies has been lacking to date.. The association between obesity and adverse perinatal outcome has ...
Adverse birth outcomes are associated with infant morbidity and mortality and with an increased likelihood of type 2 diabetes, hypertension, and cardiovascular disease in adulthood. Socioeconomic status (SES) is one of the most reliable predictors of health disparities, and although the association between SES and birth outcomes has been studied previously, this is, to our knowledge, the first review that encompasses several dimensions of SES and their influence on birth outcomes in a single article. Our review indicates that education, income, neighbourhood SES, and occupation ...
I always say its never over til the fat lady sings. But that doesnt mean I cant see that fat lady getting ready to get on stage...I can also hear her warming up, running through a few scales too. So, my suspicions were pretty much confirmed about why I didnt get my results yesterday. My results were…
99768 avhandlingar från svenska högskolor och universitet. Avhandling: Folate, Hormones and Infertility Different factors affecting IVF pregnancy outcome.
While antiretroviral therapy in pregnancy reduced vertical transmission, it also increased the frequency of several adverse birth outcomes compared with ...
Being on PrEP does not reduce male fertility or subsequent pregnancy outcomes, according to a new study, which also saw high adherence rates....
Centers for Disease Control and Prevention. Another cool fact. Your first twins ultrasound is usually achieved at about 12 weeks; you might have a ;re-pregnancy earlier for various reasons one being to verify gestation. The primary 13 weeks are often called the First Trimester. These being pregnant tests are very sensitive and really accurate, a positive take a look at means you are definitely childbirth educator certification canada. Be sure to talk to your healthcare provider pregnancyy the possible uncomfortable side effects and complications of the kind of process youll have. i am precisely the identical i am 17 weeks tmoz imporve im hardly displaying, am undecided if i have observed a distinction in my breats both sounds mad however i am small chested. I had these for bout 2 weeks now and when I do bleed its gentle. Participation on this website by a party does pre-pregnancy nutrition can improve pregnancy outcomes imply endorsement of another social gatherings content, merchandise, or ...
Pregnancy outcomes are improving among women with systemic lupus erythematosus but are still worse than those of women without the condition.
In an earlier publication, it was shown that consumption of tapwater during the first trimester of pregnancy was associated with a risk of spontaneous abortion among women who attended three prenatal clinics located in northern California between September 1981 and June 1982. Evidence for biased recall was presented. This report demonstrates that the association is limited to women interviewed by telephone and is not observed among those who completed a mail questionnaire. The possibility that the association among women interviewed by telephone is causal and that the lack of association among mail respondents is due to bias, confounding, or apparently chance fluctuations is shown to be unlikely. For instance, the probability is low that, among mail respondents, cases underreported exposure as compared with controls or that random errors were common enough to camouflage a true effect. Demographic differences between mail and telephone respondents also do not explain the results. Interviewers ...
As the authors acknowledge, information about disease activity, which is a key variable in the equation of the choice of therapy and outcomes of mother and child, was not recorded; further commentary regarding its impact on the different outcomes of the groups is merited. It is reasonable to hypothesize that patients may be receiving a thiopurine owing to more severe disease, and that this disease severity may also affect pregnancy outcomes. In fact, what was not measured may count as much as what was accounted for in the cohort. Disease activity has been related to birth outcomes and is a factor in therapy choice, and thus a confounder, by definition, of the differences found between the groups. Therefore, the lack of a difference in pregnancy and fetal outcomes in the three groups of patients with IBD does not necessarily mean that thiopurines are not independently associated with adverse outcomes. However, one would suspect that women with more severe disease activity would be in one of the ...
Pregnancy outcome and weight gain recommendations for the morbidly obese woman. Obstet Gynecol. 1998 Jan;91(1):97-102.Click here to read
Handler, A. and Rosenberg, D. (1992), Improving Pregnancy Outcomes: Public Versus Private Care for Urban, Low-Income Women. Birth, 19: 123-130. doi: 10.1111/j.1523-536X.1992.tb00669.x ...
Communications Director, AgriSafe Network. Pregnancy and fertility are often not considered when women assume farm tasks. Pesticide and other chemical exposures, zoonotic diseases and heavy lifting particularly during childbearing years, present challenges. ...
Pathak, Sangeeta (2010) Morphological and histological placental characteristics in relation to pregnancy outcome in an unselected population. Doctoral thesis, University of East Anglia. ...
Background: Imprisoned pregnant women constitute an important obstetric group about whom relatively little is known. This systematic review was conducted to identify the risk factors associated with adverse pregnancy outcome present in this group of women. Methods: The review was conducted according
A study led by Hospital for Special Surgery researchers has demonstrated that women who have a specific type of antibody that interferes with blood vessel function are at risk for adverse pregnancy outcomes and that other ...
SYDNEY, AUSTRALIA - Women at high risk of early preeclampsia who show signs of abnormal hemodynamic function earlier in pregnancy may be more likely to have adverse pregnancy outcomes, new data suggest.
(2013) Edvardsson et al. BMC Public Health. BACKGROUND: Overweight and obesity in pregnancy increase the risk of several adverse pregnancy outcomes. However, both mothers and fathers health play an important role for long-term health outco...
Irish drugs and alcohol research, data, policy and sources of evidence on prevention, treatment, rehabilitation, crime and consequences.
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Background: Placental malaria (PM) causes adverse pregnancy outcomes in the mother and her foetus. It is difficult to study PM directly in humans due to ethical challenges. This study set out to bridge this gap by determining ...
TY - JOUR. T1 - Pregnancy outcomes following placement of elective, urgent and emergent cerclage. AU - Nelson, Latasha. AU - Dola, Thao. AU - Tran, Thuc. AU - Carter, Margaret. AU - Luu, Henry. AU - Dola, Chi. PY - 2009/11/9. Y1 - 2009/11/9. N2 - Objective. To describe pregnancy outcomes following elective history-indicated, urgent ultrasound-indicated or emergent physical-exam indicated cerclage placement. Materials and Methods.Study design was retrospective chart review. Women with singleton gestation and cervical cerclage were categorised into: elective, urgent and emergent group. Results.One hundred and thirty-three women were included; 89 in elective, 26 in urgent and 18 in emergent group. Difference was detected when elective and urgent groups were compared with emergent group for: gestation at delivery 35.9 ± 5.1 vs. 34.2 ± 5.9 vs. 29.3 ± 7.2 weeks, respectively, P , 0.05, delivery beyond 36 weeks, 73.9, 57.7vs. 23.5, respectively, P , 0.05, neonatal death 6.8, 9.5vs. 43.8, ...
Periodontal diseases affect the majority of the population either as gingivitis or periodontitis. Recently there have been many studies that link or seek to find a relationship between periodontal disease and other systemic diseases including, cardiovascular disease, diabetes, stroke, and adverse pregnancy outcomes. For adverse pregnancy outcomes, the literature is inconclusive and the magnitude of the relationship between these 2 has not been fully decided. The goal of this paper is to review the literature regarding periodontal diseases and adverse pregnancy outcomes, and provide oral health care providers with resources to educate their patients. Alternatively, this paper will also discuss what is occurring to help increase the availability of care for pregnant women and what oral health care providers can do to help improve these issues.. ...
Gender is known to influence pregnancy outcomes. Recent studies have reported an association between air pollution exposure and adverse pregnancy outcomes, but gender differences have not been considered. In order to assess the current evidence of the interactive effects between gender and air pollution on pregnancy outcomes we undertook a systematic literature review. Using a comprehensive list of keywords, English language articles published between 1966 and 2005 were retrieved from major databases. Additional information on gender was obtained from the study authors. Studies were included if they contained well-defined measurements of ambient air pollutants, investigated pregnancy outcomes and reported estimates by gender. In total 11 studies were included. The quality of the studies was assessed using the framework in Systematic Reviews in Health Care Meta-analysis in context and Brackens Guidelines. Of the 11 studies, four evaluated low birth weight (LBW); one each evaluated very low birth ...
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) established the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b) to study women for whom the current pregnancy will lead to their first delivery (nulliparas). About 40% of pregnant women in the United States are nulliparas. Because little or no information from previous pregnancy outcomes is available to guide assignment of risk or mitigating interventions, adverse pregnancy outcomes in nulliparas are especially unpredictable. The underlying mechanisms of adverse pregnancy outcomes such as preterm birth, preeclampsia, fetal growth restriction and stillbirth are interrelated and therefore will be evaluated as part of this study. The information gained will benefit women who are pregnant or who are considering pregnancy and their physicians. In addition, the knowledge will support future research aimed at improving care and health outcomes for a critical group of at-risk women who ...
Background: Smoking habit acts as the risk factor for Periodontal disease and Adverse pregnancy outcomes. Mild maternal smoking might also cause whopping adverse pregnancy outcomes. Lack of awareness in pregnant woman regarding the adverse outcome of pregnancy with maternal smoking is very common in developing countries like India. The objective of this study was to evaluate knowledge and awareness of south Indian pregnant female about maternal smoking and its association with adverse pregnancy outcomes. Materials and Methods: Multiple optioned 21 questionnaires was prepared with four categories i.e about smoking habit, stress levels, smoking effects on pregnancy outcomes, and discontinuing the habit. Maternal smoking also related with stress levels. Questionnaire forms were distributed to 440 pregnant patients who visited primary health centers in primary health care centers in several parts of south India. Answers were evaluated based on the current evidence available. Results: Most of the ...
Presently, the matter of pregnancy outcomes of patients with pregnancy related AKI (PR-AKI) were disputed. Thus, we conducted a meta-analysis to evaluate the impact of PR-AKI on pregnancy outcomes. We systematically searched MEDLINE, Embase, VIP, CNKI and Wanfang Databases for cohort or case-control studies in women with PR-AKI and those without AKI as a control group to assess the influence of PR-AKI on pregnancy outcomes and kidney outcome. Reduction of odd ratio (OR) was calculated by a random-effects model. One thousand one hundred fifty two articles were systematically reviewed, of those 11 studies were included, providing data of 845 pregnancies in 834 women with PR-AKI and 5387 pregnancies in 5334 women without AKI. In terms of maternal outcomes, women with PR-AKI had a greater likelihood of cesarean delivery (OR, 1.49; 95% confidence interval [CI], 1.37 to 1.61), hemorrhage (1.26; 1.02 to 1.56), HELLP syndrome (1.86; 1.41 to 2.46), placental abruption (3.13; 1.96 to 5.02), DIC (3.41; 2.00 to 5
There is a growing number of studies on the association between ambient air pollution and adverse pregnancy outcomes, but their results have been inconsistent. Consequently, a comprehensive review of this research area is needed. There was a wide variability in studied pregnancy outcomes, observed gestational windows of exposure, observed ambient air pollutants, applied exposure assessment methods and statistical analysis methods Gestational duration, preterm birth, (low) birth weight, and small for gestational age/intrauterine growth restriction were most commonly investigated pregnancy outcomes. Gestational windows of exposure typically included were whole pregnancy period, 1st, 2nd, 3rd trimester, first and last gestational months. Preterm birth was the outcome most extensively studied across various gestational windows, especially at the beginning and at the end of pregnancy. Particulate matter, nitrogen dioxide, ozone, and carbon monoxide were the most commonly used markers of ambient air ...
There are two main situations where screening for the management of STI in pregnancy is an option for resource poor countries. This is because there are cheap screening tests available for the diagnosis of both maternal syphilis and HIV infection.. Given the impact maternal syphilis has on pregnancy outcome, screening and treatment of syphilis in pregnant women at least once during pregnancy should be performed. In most resource poor developing countries, the RPR test is the most common screening assay. This test is cheap and simple although, like other non-treponemal tests, it is susceptible to false positive reactions from other maternal infections or autoimmune disease. These include common conditions like pregnancy, infection, measles, and malaria. Biological false positive (BFP) reactions are common in malaria endemic areas and may account for up to 30% of reactive RPR tests.6 Although the CDC recommends screening at the first ANC visit and again in the third trimester in high prevalence ...
TY - JOUR. T1 - Subsequent pregnancy outcomes in recurrent miscarriage patients with a paternal or maternal carrier of a structural chromosome rearrangement. AU - Sugiura-Ogasawara, Mayumi. AU - Aoki, Koji. AU - Fujii, Tomoyuki. AU - Fujita, Tomio. AU - Kawaguchi, Rie. AU - Maruyama, Tetsuo. AU - Ozawa, Nobuaki. AU - Sugi, Toshitaka. AU - Takeshita, Toshiyuki. AU - Saito, Shigeru. PY - 2008/7/1. Y1 - 2008/7/1. N2 - Information concerning the prognosis of subsequent pregnancies in patients with reciprocal translocations is limited. This study was performed to determine the percentage success rate with first pregnancies after ascertainment of a carrier status. A total of 2,382 couples with a history of two or more consecutive miscarriages were studied in multicenters. The prevalence of an abnormal chromosome in either partner was examined, and subsequent success rates were compared between cases with and without an abnormal karyotype in either partner. A total of 129 couples (5.4%) had an abnormal ...
The use of oocyte donation (OD) has increased continuously over the last three decades, and it is now an indispensable part of assisted reproductive technology (ART). With OD, it has become possible to overcome the biological barrier of ovarian follicle pool depletion and the general age-related decline in fertility. This review contains a thorough appraisal of the safety of OD with an analysis of short-term pregnancy outcomes. Salient up-to-date evidence was evaluated, which revealed that in comparison with both IVF with autologous oocytes, and naturally conceived pregnancies, there is: (i) an increased risk of hypertensive disorders of pregnancy and preeclampsia; (ii) an increased risk of low birth weight and preterm birth and (iii) an increased risks of obstetric emergencies, following OD treatment. As a precaution, it is therefore highly encouraged to perform only single embryo transfer (SET) and to prescribe prophylactic low-dose aspirin during OD pregnancies. ...
Background/Purpose: Actually better control of rheumatoid arthritis (RA) activity leads to new interrogations and daily questions about pregnancy. Only few studies have studied pregnancy outcomes in women with RA, and results have shown some discrepancies. The objective is to determine the effect of Rheumatoid Arthritis on pregnancy outcomes, specially hypertension and preeclampsia, low birth weight, preterm birth, perinatal mortality, congenital malformation and cesarean section in women with Rheumatoid Arthritis Methods: A litterature search was performed from Medline and Cochrane databases for articles published in english from 1955 to May 2016. Studies were eligible if they presented prevalence study, including national birth registry. Population were women with Rheumatoid Arthritis and keys terms related to pregnancy outcomes. Meta-analysis were performed to assess odds-ratios (OR) for each studied group using the inverse variance approach to estimate pooled OR with their 95% confidence ...
We assessed the effects of physical activity on pregnancy outcome in 2741 Filipino women identified during pregnancy as part of a two-year longitudinal study. Specific elements of physical activity hypothesized to be relevant to pregnancy outcome were posture, energy expenditure, and physical stress. Variables were developed for nine household and 48 formal and informal economic activities. Analyses were stratified by whether the woman performed formal waged work outside of the home, income-related activity at home, or was economically inactive. Results show that traditional definitions of physical activity and work based on participation in the formal labour force ignore a sizeable amount of home economic production, as well as the physical demands of housework. We saw no difference in risk of low birthweight or preterm delivery in economically active compared to economically inactive women. However, we found that increased amounts of standing activity affected pregnancy outcome in certain ...
TY - JOUR. T1 - Preconceptional cardiovascular health and pregnancy outcomes in women with systemic lupus erythematosus. AU - Eudy, Amanda M.. AU - Siega-Riz, Anna Maria. AU - Engel, Stephanie M.. AU - Franceschini, Nora. AU - Howard, Annie Green. AU - Clowse, Megan E.B.. AU - Petri, Michelle. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Objective. To estimate the effects of preconceptional cardiovascular (CV) health, measured by American Heart Association (AHA) guidelines, on pregnancy outcomes in women with systemic lupus erythematosus (SLE). Methods. The study included patients in the Hopkins Lupus Pregnancy Cohort. Body mass index (BMI), total cholesterol, and blood pressure (BP) in the most recent clinic visit prior to conception or first trimester were used to determine CV health (ideal, intermediate, or poor health) based on AHA definitions. Outcomes included preterm birth, gestational age at birth, and small for gestational age (SGA). Multivariable linear and logistic regression models with ...
non viable pregnancy - MedHelps non viable pregnancy Center for Information, Symptoms, Resources, Treatments and Tools for non viable pregnancy. Find non viable pregnancy information, treatments for non viable pregnancy and non viable pregnancy symptoms.
Time-to-pregnancy (TTP) has never been studied in an African setting and there are no data on the rates of adverse pregnancy outcomes in South Africa. The study objectives were to measure TTP and the rates of adverse pregnancy outcomes in South Africa, and to determine the reliability of the questionnaire tool. The study was cross-sectional and applied systematic stratified sampling to obtain a representative sample of reproductive age women for a South African population. Data on socio-demographic, work, health and reproductive variables were collected on 1121 women using a standardized questionnaire. A small number (n = 73) of randomly selected questionnaires was repeated to determine reliability of the questionnaire. Data was described using simple summary statistics while Kappa and intra-class correlation statistics were calculated for reliability. Of the 1121 women, 47 (4.2%) had never been pregnant. Mean gravidity was 2.3 while mean parity was 2.0 There were a total of 2467 pregnancies; most (87%)
Background: Exposure to alcohol and tobacco during pregnancy may lead to developmental disorders in the foetus and can also adversely impact pregnancy outcomes and the newborns health status. Objective: Assessment of alcohol consumption and tobacco use during pregnancy as well as their impact on pregnancy outcomes and birth parameters of the newborn in a selected group of mothers with children aged ≤ 2 years. Material and methods: The study was conducted in 104 mothers with children aged ≤ 2 years living in the Mazowiecki Voivodeship. A questionnaire was used for assessing selected lifestyle parameters tobacco and alcohol use, dietary supplements use, physical activity during pregnancy, socio-demographic characteristics as well as childrens birth parameters (birth weight, length, head circumference, chest circumference). Data were analyzed statistically using logistic regression analysis, Spearmans rang correlation, the Mann-Whitney U, Kruskal-Wallis, Student-t, Tukey and Chi2 tests ...
Authors: B Bello, D Kielkowski, D Heederik, K Wilson.. Source: BMC Public Health 2010, Sept 21; 10:565.. Summary:. Background: Time-to-pregnancy (TTP) has never been studied in an African setting and there are no data on the rates of adverse pregnancy outcomes in South Africa. The study objectives were to measure TTP and the rates of adverse pregnancy outcomes in South Africa, and to determine the reliability of the questionnaire tool.. Methods: The study was cross-sectional and applied systematic stratified sampling to obtain a representative sample of reproductive age women for a South African population. Data on socio-demographic, work, health and reproductive variables were collected on 1121 women using a standardized questionnaire. A small number (n = 73) of randomly selected questionnaires was repeated to determine reliability of the questionnaire. Data was described using simple summary statistics while Kappa and intra-class correlation statistics were calculated for ...
Preterm (PT) and Low birth weight (LBW) are considered to be the most relevant biological determinants of newborn infants survival, both in developed and in developing countries. Numerous risk factors for PT and LBW have been defined in the literature. Infections of the genitourinary tract infections along with various biological and genetic factors are considered to be the most common etiological factors for PT/LBW deliveries. However, evidence suggests that sub-clinical infection sites that are also distant from the genitor-urinary tract may be an important cause for PT/LBW deliveries. Maternal periodontal status has also been reported by many authors as a possible risk factor for PT and LBW, though not all of the actual data support such hypothesis. The aim of this paper is to review the evidence from various published literature on the association between the maternal periodontal status and adverse pregnancy outcomes. Although this review found a consistent association between periodontitis ...
TY - JOUR. T1 - Predictors of pregnancy outcomes in patients with lupus. T2 - A cohort study. AU - Buyon, Jill P.. AU - Kim, Mimi Y.. AU - Guerra, Marta M.. AU - Laskin, Carl A.. AU - Petri, Michelle. AU - Lockshin, Michael D.. AU - Sammaritano, Lisa. AU - Branch, D. Ware. AU - Porter, T. Flint. AU - Sawitzke, Allen. AU - Merrill, Joan T.. AU - Stephenson, Mary D.. AU - Cohn, Elisabeth. AU - Garabet, Lamya. AU - Salmon, Jane E.. N1 - Publisher Copyright: © 2015 American College of Physicians. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.. PY - 2015/8/4. Y1 - 2015/8/4. N2 - Background: Because systemic lupus erythematosus (SLE) affects women of reproductive age, pregnancy is a major concern. Objective: To identify predictors of adverse pregnancy outcomes (APOs) in patients with inactive or stable active SLE. Design: Prospective cohort. Setting: Multicenter. Patients: 385 patients (49% non-Hispanic white; 31% with prior nephritis) with SLE in the PROMISSE (Predictors of Pregnancy ...
In 2001-2008, 2.9% of pregnant North Carolina women were drivers in one or more crashes. After a single crash, compared to not being in a crash, pregnant drivers had slightly elevated rates of preterm birth and premature rupture of the membranes. Following a second or subsequent crash, pregnant drivers had more highly elevated rates of preterm birth, premature rupture of the membranes and stillbirth. Stillbirth rates were elevated following crashes involving unbelted pregnant drivers compared to belted pregnant drivers ...
New England Journal of Medicine March 30, 2017 Vol. 376 No. 13 Original Article Quadrivalent HPV Vaccination and the Risk of Adverse Pregnancy Outcomes Nikolai M. Scheller, M.D., Björn Pasternak, M.D., Ph.D., Ditte Mølgaard-Nielsen, M.Sc., Henrik Svanström, Ph.D., and Anders Hviid, Dr.Med.Sci. N Engl J Med 2017; 376:1223-1233 March 30, 2017 DOI: 10.1056/NEJMoa1612296 Abstract…
Background: While the relationship between hemoglobin (Hb) concentrations and pregnancy outcomes has been studied often, most reports have focused on a specific Hb cutoff used to define anemia. Fewer studies have evaluated pregnancy outcomes across the entire range of Hb values. Moreover, to date, most studies of the relationship of Hb concentrations to pregnancy outcomes have been done in high-income countries. Thus, we have sought to determine the relationship between the range of maternal Hb concentrations and adverse birth outcomes among South Asian pregnant women.Methods: For this study, we used data collected from two South Asian countries (Pakistan - Sindh Province and two sites in India - Belagavi and Nagpur) in a prospective maternal and newborn health registry study. To assess the association between Hb concentrations and various maternal and fetal outcomes, we classified the Hb concentrations into seven categories. Regression analyses adjusting for multiple potential confounders were
TY - JOUR. T1 - The epidemiology of pregnancy outcomes in rural Burkina Faso. AU - Bell, Jacqueline S.. AU - Ouedraogo, Moctar. AU - Ganaba, Rasmane. AU - Sombie, Issiaka. AU - Byass, Peter. AU - Baggaley, Rebecca F.. AU - Filippi, Veronique. AU - Fitzmaurice, Ann E.. AU - Graham, Wendy J.. PY - 2008/7. Y1 - 2008/7. N2 - Objectives To describe levels and causes of pregnancy-related mortality and selected outcomes after pregnancy (OAP) in two districts of Burkina Faso.Methods A household census was conducted in the two study districts, recording household deaths to women aged 12-49 years from 2001 to 2006. Questions on pregnancy outcomes in the last 5 years for resident women of reproductive age were included, and an additional method - direct sisterhood - was added in part of the area. Adult female deaths were followed-up with verbal autopsies (VA) with household members. A probabilistic model for interpreting VA data (InterVA-M) was used to determine distributions of probable causes of death. ...
Design - Comparative study of pregnancy outcome for parturients who had stayed in an antenatal village and for those admitted directly from the community. Setting - A rural hospital in Zimbabwe. Outcome measures - Birthweight, perinatal mortality and degree of obstetrical intervention. Results - Women who stayed in the antenatal village experienced better pregnancy outcome than women admitted directly from the community. Birthweight was greater, perinatal mortality lower, and obstetrical intervention less often required in the antenatal village group. Conclusions - Lack of randomisation, differences between the two groups in antenatal risk factors, and lack of information relating to socio-economic status suggest that generalisations beyond the specific case be made cautiously.
BACKGROUND: Malaria in pregnancy (MiP) is a major public health problem in endemic areas of sub-Saharan Africa and has important consequences on birth outcome. Because MiP is a complex phenomenon and malaria epidemiology is rapidly changing, additional evidence is still required to understand how best to control malaria. This study followed a prospective cohort of pregnant women who had access to intensive malaria screening and prompt treatment to identify factors associated with increased risk of MiP and to analyse how various characteristics of MiP affect delivery outcomes. METHODS: Between October 2006 and May 2009, 1,218 pregnant women were enrolled in a prospective cohort. After an initial assessment, they were screened weekly for malaria. At delivery, blood smears were obtained from the mother, placenta, cord and newborn. Multivariate analyses were performed to analyse the association between mothers characteristics and malaria risk, as well as between MiP and birth outcome, length and weight at
To study the effect of endometrial thickness and pattern measured using ultrasound upon pregnancy outcomes in patients undergoing IVF-ET. One thousand nine hundred thirty-three women undergoing IVF treatment participated in the study. We assessed and recorded endometrial patterns and thickness on the day of human chorionic gonadotropin (hCG) administration. Receiver operator curves (ROC) were used to determine the predictive accuracy of endometrial thickness. Cycles were divided into 3 groups depending on the thickness (group 1: ≤ 7 mm; group 2: | 7 mm to ≤ 14 mm; group 3: | 14 mm). Each group was subdivided into three groups according to the endometrial pattern as follows: pattern A (a triple-line pattern consisting of a central hyperechoic line surround by two hypoechoic layers); pattern B (an intermediate isoechogenic pattern with the same reflectivity as the surrounding myometrium and a poorly defined central echogenic line); and pattern C (homogenous, hyperechogenic endometrium). Clinical
Many studies have been conducted to examine whether Caesarean Section (CS) or vaginal birth (VB) was optimal for better maternal and neonatal outcomes in preterm births. However, findings remain unclear. Therefore, this secondary analysis of World Health Organization Global Survey (GS) and Multi-country Survey (MCS) databases was conducted to investigate outcomes of preterm birth by mode of delivery. Our sample were women with singleton neonates (15,471 of 237 facilities from 21 countries in GS; and 15,053 of 239 facilities from 21 countries in MCS) delivered between 22 and |37 weeks of gestation. We assessed association between mode of delivery and pregnancy outcomes in singleton preterm births by multilevel logistic regression adjusted for hierarchical data. The prevalences of women with preterm birth delivered by CS were 31.0% and 36.7% in GS and MCS, respectively. Compared with VB, CS was associated with significantly increased odds of maternal intensive care unit admission, maternal near miss, and
Sponsor. National Institutes of Health (NIH). Principal Investigator. Dr. Hazel Nichols, Epidemiology. Project Run Dates. 7/01/2017 to 6/30/2022. Summary. In the U.S., more than 45,000 women are diagnosed with cancer during adolescence and young adulthood (AYA, ages 15-39 at diagnosis) each year. Fertility and reproductive outcomes are critical issues for AYA cancer survivors but little is known about the effect of diagnosis and treatment on the clinical course and outcome of future pregnancy. Our study will leverage existing data sources to assess clinical pregnancy outcomes among women with the most common AYA cancers (lymphoma, breast, melanoma, thyroid and gynecologic cancer) that account for ,70% of all diagnoses. Our findings will provide urgently needed answers that can be directly applied to fertility preservation, preconception, and prenatal counseling.. Data for this study come from the Kaiser Permanente (KP) Northern and Southern California integrated healthcare systems and from an ...
Results: Of 364,363 singleton pregnancies resulting in live or stillbirths 1,969 (0.5%) were in women with IBD. Women with CD were more likely to have pre-term births (OR=1.42 95%CI;1.12-1.79), babies with low birth weights (OR=1.39;1.05-1.83) and postpartum haemorrhage (OR=1.27;1.04-1.55) whereas women with UC were only at increased risk of pre-term births with an absolute risk difference of ,2.7%. These risks remained independent of caesarean section (CS). Prior surgery for IBD did not increase risk of adverse birth outcomes or pregnancy related complications compared to cases without surgery, however women with IBD were more likely to have an elective CS ...
There has been limited research addressing whether behavioural change in relation to smoking is maintained throughout pregnancy and the effect on perinatal outcomes. A cohort study addressed lifestyle behaviours of 907 women who booked for antenatal care and delivered in a large urban teaching hospital in 2010-2011. Adverse perinatal outcomes were compared for
Maternal anthropometry and pregnancy outcomes: a WHO collaborative study , Maternal anthropometry and pregnancy outcomes: a WHO collaborative study , کتابخانه دیجیتال دانشگاه علوم پزشکی اصفهان
Some, but not all, studies have shown an association between in utero exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants and adverse pregnancy outcomes, including preterm delivery, low birth weight, and lower Apgar scores. One of the difficulties in estimating the risk for adverse outcomes in this population is that studies have used varying methodologies and have relied on different means of identifying and classifying neonatal outcomes. Furthermore, many of these studies have not taken into consideration other variables that may affect neonatal outcomes, including the use of other medications, smoking, and maternal mental illness. We often question whether depression itself (as opposed to the antidepressants used to treat it) may contribute to adverse outcomes. This question stems from early research conducted by Steer and colleagues (!992) and Orr and Miller (1995). Steer observed that the risk of a poor pregnancy outcome rose by 5-7% for each point increase on the Beck ...
The Adverse Pregnancy Outcomes Reporting System records adverse pregnancy outcomes in infants with congenital anomalies (birth defects) and other serious neonatal conditions. This report describes the county-specific prevalence rates of seven groups of major birth defects, a listing of the disease codes and a brief description of each defect and similar information about other adverse pregnancy outcomes ...
Impaired fetal growth and preterm birth are the leading causes of neonatal and infant mortality worldwide and there is a growing scientific literature suggesting that environmental exposures during pregnancy may play a causal role in these outcomes. Our purpose was to assess the environmental exposure of the Fetal Growth Longitudinal Study (FGLS) participants in the multinational INTERGROWTH-21(st) Project. First, we developed a tool that could be used internationally to screen pregnant women for such exposures and administered it in eight countries on a subsample (n = 987) of the FGLS participants. The FGLS is a study of fetal growth among healthy pregnant women living in relatively affluent areas, at low risk of adverse pregnancy outcomes and environmental exposures. We confirmed that most women were not exposed to major environmental hazards that could affect pregnancy outcomes according to the protocols entry criteria. However, the instrument was able to identify some women that reported various
The obstetrical and gynecological manifestation of Crohns disease is particularly challenging for young women and demands special attention, according to an article in the International Journal of Womens Health. Pregnant women with CD are considered high-risk patients due to associated complications. Some of the prevalent complications are premature birth, low birth weight, and congenital anomalies. To minimize the risk for adverse pregnancy/birth outcomes, it is recommended that remission of CD symptoms be achieved before conception. Treatment of CD in pregnant women is similar to that among the nonpregnant population, and there is no valid reason to terminate it, since most of the drugs are proven to be safe. Women with CD who wish to conceive or are already pregnant need to be properly advised according to the newest guidelines on the subject, given by the European Crohns and Colitis Organization. Gynecological manifestations are another special feature of CD. They are important in that ...
Maternal supraphysiological estradiol (E2) environment during pregnancy leads to adverse perinatal outcomes. However, the influence of oocyte exposure to high E2 levels on perinatal outcomes remains unknown. Thus, a retrospective cohort study was conducted to explore the effect of high E2 level induced by controlled ovarian stimulation (COH) on further outcomes after frozen embryo transfer (FET). The study included all FET cycles (n = 10,581) between 2014 and 2017. All cycles were categorized into three groups according to the E2 level on the day of the human Chorionic Gonadotropin trigger. Odds ratios (ORs) and their confidence intervals (CIs) were calculated to evaluate the association between E2 level during COH and pregnancy outcomes and subsequent neonatal outcomes. From our findings, higher E2 level was associated with lower percentage of chemical pregnancy, clinical pregnancy, ongoing pregnancy, and live birth as well as increased frequency of early miscarriage. Preterm births were more ...
This is the most comprehensive cohort study of prepregnancy care in women with type 1 diabetes in the U.K., describing glycemic control throughout pregnancy and multiple pregnancy outcomes. In addition, we have complete follow-up on a large and recent unselected clinic population, a collection of monthly A1C measurements from a single laboratory, and careful assessment of potential confounding factors. The prepregnancy clinic was attended by 38% of women, which is in keeping with findings from the CEMACH report (1). There was a significant increase in numbers of women receiving prepregnancy care during the study. This figure is lower than that of 58% reported in a recent study from Denmark (22). In that study, preconception guidance was not defined, and only 34% women were monitoring their blood glucose at the time of conception compared with 100% women in our study. This might suggest that the preconception guidance had been limited compared with prepregnancy care in our study.. Our study shows ...
Pregnancy Outcomes in US Prisons, 2016-2017 Carolyn Sufrin MD, PhD, Lauren Beal MPH, Jennifer Clarke MD, MPH, Rachel Jones PhD, and William D. Mosher PhD Published online: March 21, 2019 Objectives. To collect national data on pregnancy frequencies and outcomes among women in US state and federal prisons.
BACKGROUND: The prevalence of obesity amongst women bearing children in Australia is rising and has important implications for obstetric care. The aim of this study was to assess the prevalence and impact of mothers being overweight and obese in early to mid-pregnancy on maternal, peripartum and neonatal outcomes.. METHODS: A secondary analysis was performed on data collected from nulliparous women with a singleton pregnancy enrolled in the Australian Collaborative Trial of Supplements with antioxidants Vitamin C and Vitamin E to pregnant women for the prevention of pre-eclampsia (ACTS). Women were categorized into three groups according to their body mass index (BMI): normal (BMI 18.5-24.9 kg/m2); overweight (BMI 25-29.9 kg/m2) and; obese (BMI 30-34.9 kg/m2). Obstetric and perinatal outcomes were compared by univariate and multivariate analyses.. RESULTS: Of the 1661 women included, 43% were overweight or obese. Obese women were at increased risk of pre-eclampsia (relative risk (RR) 2.99 [95% ...
The association between fluoroquinolones and arthropathy, although observed in immature animals and rarely reported in humans, has resulted in the restricted use of fluoroquinolones during pregnancy. Data from recent reports suggest that quinolone administration to children and adolescents with cystic fibrosis is safe on the basis of both clinical and magnetic resonance imaging assessments (4). However, since these observations have focused on children and adolescents, it is unclear whether in utero exposure to quinolones and their potential deposition in fetal cartilage are associated with any long-term musculoskeletal dysfunctions. Our data, which we obtained using the Denver Developmental Scale, suggest that in utero exposure to quinolones is not associated with clinically significant major musculoskeletal dysfunctions. This tool is very limited in evaluating subtle joint changes that would have been detected only by sensitive methods. Magnetic resonance imaging of weight-bearing joints of ...
During pregnancy, CKD increases both maternal and fetal risk. Adverse maternal outcomes include progression of underlying renal dysfunction, worsening of urine protein, and hypertension, whereas adverse fetal outcomes include fetal loss, intrauterine growth restriction, and preterm delivery. As such, pregnancy in young women with CKD is anxiety provoking for both the patient and the clinician providing care, and because the heterogeneous group of glomerular diseases often affects young women, this is an area of heightened concern. In this invited review, we discuss pregnancy outcomes in young women with glomerular diseases. We have performed a systematic review in attempt to better understand these outcomes among young women with primary GN, we review the studies of pregnancy outcomes in lupus nephritis, and finally, we provide a potential construct for management. Although it is safe to say that the vast majority of young women with glomerular disease will have a live birth, the counseling that we can
The risk of preeclampsia and different pregnancy problems may be higher for expectant moms whove a historical past of acute kidney injury, a brand new research finds, even when kidney perform is regular previous to pregnancy.
Study objective-To examine the effect of socioeconomic status on pregnancy outcome in an urbanised area in a rapidly developing country. Methods-A cohort of 1797 pregnant women who attended antenatal care clinics at the two 700 bed hospitals in Hatyai city was recruited from September 1994 to November 1995. The pregnant women were followed up...
Treatment of gestational diabetes reduces serious perinatal morbidity and may also improve the womans health-related quality of life.
Study Question: To what degree do records registered in the Netherlands Perinatal Registry (PRN) agree with self-report in a Study Question: naire on pregnancy outcomes in childhood cancer survivors (CCSs)? Summary Answer: This study suggests that self-reported pregnancy outcomes of CCSs agree well with registry data and that outcomes reported by CCSs agree better with registry data than do those of controls. What is Known Already: Many studies have shown that childhood cancer treatment may affect fertility outcomes in female CCSs; however, these conclusions were often based on questionnaire data, and it remains unclear whether self-report agrees well with more objective sources of information. Study Design , Size, Duration In an nationwide cohort study on fertility (inclusion period January 2008 and April 2011, trial number: NTR2922), 1420 CCSs and 354 sibling controls were invited to complete a questionnaire regarding socio-demographic characteristics and reproductive history. In total, 879 ...
Many patients with IBDs such as Crohns disease and ulcerative colitis require immunosuppressive biologic therapies to control disease activity, which is important in women because active IBD has been associated with adverse pregnancy outcomes. Multiple retrospective studies have found no association between treatment of pregnant women with IBD using biologic agents such as antagnoists of tumor necrosis factor (anti-TNF) and adverse pregnancy outcomes.. However, some of these drugs can cross the placenta; anti-TNF agents such as adalimumab or infliximab can be detected in infants until 12 months of age. In contrast, certolizumab pegol, which is a polyethylene glycolylated FaB immunoglobulin, does not bind to the neonatal Fcγ receptor that mediates transplacental transfer and was not found in infant or cord blood.. There are limited data on the long-term effects of this exposure on the development of the neonatal immune system.. Dawn B. Beaulieu et al performed a large, prospective study to ...
Results 28 pregnancies in 20 women (26±6 years old) with PAH-CHD were managed during this period. There were 18 complete pregnancies (≥20 weeks gestation (WG)), 8 abortions and 2 miscarriages. Six (33%, 95% CI (11.9 to 54.3)) patients experienced severe cardiac events. The concerned women had lower resting oxygen saturation (79.6±4.1% vs 89.3±3.8%, p,0.01). The most common cardiac complications during the complete pregnancies were heart failure (n=4) and severe hypoxaemia (n=5). Heart failure was overall severe, requiring inotropic treatment in three patients, mechanical circulatory support in one and led to one maternal death (mortality=5.0% 95% CI (0.1 to 24.9)). Obstetrical complications occurred in 25% of pregnancies. Small for gestational age was diagnosed in 39% (7/18) of fetuses. 12/18 (67%) pregnancies were delivered by caesarean section, of which 10 in emergency for obstetrical reason. Prematurity was frequent (78%), but no neonatal death occurred. ...
Pregnancy and birth outcomes[edit]. Evidence about radiation-related pregnancy and birth outcomes comes from studies of nuclear ... 500 mSv between the 10th and 40th day of pregnancy, the period of organogenesis during which the organs are formed. After the ... "Radiation exposure and pregnancy". Journal of Vascular Surgery. 53 (1): 28S-34S. doi:10.1016/j.jvs.2010.05.140. Retrieved 15 ... that fetal malformations are a greater risk if a woman is exposed to high doses of nuclear-related radiation in early pregnancy ...
A 2001 review suggested older men have decreased pregnancy rates, increased time to pregnancy, and increased infertility at a ... Birth outcomes[edit]. A systematic review published in 2010 concluded that the graph of the risk of low birthweight in infants ... Pregnancy effects[edit]. Several studies have reported that advanced paternal age is associated with an increased risk of ... "Advanced Paternal Age Is Associated with Impaired Neurocognitive Outcomes during Infancy and Childhood". PLoS Med. 6 (3): e40. ...
During pregnancy, testing can be performed on the placenta (chorionic villus sampling) or the fluid around the fetus ( ... Fetal and maternal outcome". Chest. 118 (1): 85-91. doi:10.1378/chest.118.1.85. PMID 10893364. S2CID 32289370. Guimbellot J, ... Huth MM, Zink KA, Van Horn NR (2005). "The effects of massage therapy in improving outcomes for youth with cystic fibrosis: an ... The disease appears only when two of these carriers have children, as each pregnancy between them has a 25% chance of producing ...
Landesman-Dwyer, S (1982). "Maternal drinking and pregnancy outcome". Applied Research in Mental Retardation. 3 (3): 241-63. ... It is even possible that the baby throughout pregnancy will develop heart defects such as ventricular septal defect or atrial ... Brief Interventions for alcohol abuse reduce the incidence of unsafe sex, sexual violence, unplanned pregnancy and, likely, STD ...
"Maternal Lyme borreliosis and pregnancy outcome". International Journal of Infectious Diseases. 14 (6): e494-8. doi:10.1016/j. ... adverse pregnancy outcomes are possible with untreated infection; prompt treatment with antibiotics reduces or eliminates this ... Walsh CA, Mayer EW, Baxi LV (January 2007). "Lyme disease in pregnancy: case report and review of the literature". Obstetrical ... Transmission can occur across the placenta during pregnancy and as with a number of other spirochetal diseases, ...
"Vitamin K antagonists and pregnancy outcome. A multi-centre prospective study". Thromb. Haemost. 95 (6): 949-57. doi:10.1160/ ... "Outcomes of Discontinuing Rivaroxaban Compared With Warfarin in Patients With Nonvalvular Atrial Fibrillation: Analysis From ...
Multiple Pregnancy: Epidemiology, Gestation & Perinatal Outcome. Taylor and Francis. p. 34. ISBN 978-1-85070-666-3. "What's in ... Multiple pregnancies are much less likely to carry to full term than single births, with twin pregnancies lasting on average 37 ... Occasionally, a woman will suffer a miscarriage early in pregnancy, yet the pregnancy will continue; one twin was miscarried ... However, in most cases, the intrauterine pregnancy can be salvaged.[citation needed] For otherwise healthy twin pregnancies ...
"Factors influencing pregnancy outcome after trauma". The American Surgeon. 58 (9): 594-8, discussion 598. PMID 1524327. " ...
Toward Improving the Outcome of Pregnancy (1993). *^ Singh, Meharban (2010). Care of the Newborn. pp. 4-5. ...
A review of pregnancy outcomes in women with acrodermatitis enteropathica, reported that out of every seven pregnancies, there ... Shah D, Sachdev HP (January 2006). "Zinc deficiency in pregnancy and fetal outcome". Nutrition Reviews. 64 (1): 15-30. doi: ... RDA for pregnancy is 11 mg/day. RDA for lactation is 12 mg/day. For infants up to 12 months the RDA is 3 mg/day. For children ... Zinc deficiency during pregnancy can negatively affect both the mother and fetus. Animal studies indicate that maternal zinc ...
Soriano D, Dessolle L, Poncelet C, Benifla JL, Madelenat P, Darai E (June 2003). "Pregnancy outcome after laparoscopic and ... Also, after a pregnancy, myomas tend to shrink naturally. However, in selected cases myomectomy may become necessary during ... It is well known that myomectomy surgery is associated with a higher risk of uterine rupture in later pregnancy. Thus, women ... Generally, surgeons tend to stay away from operative interventions during the pregnancy because of the risk of haemorrhage and ...
This type of mosaicism is most often associated with normal pregnancy outcome. Type 2 CPM- The error occurs in a non-fetal cell ... However, some pregnancies with CPM experience prenatal or perinatal complications. The pregnancy loss rate in pregnancies with ... The pregnancy outcome is strongly chromosome specific. The most frequently seen trisomic cells in confined placental mosaicism ... However, it is not accurate to use these associations to try to predict pregnancy outcome based on the percent of trisomic ...
Ehrenberg, H (2003). "Low maternal weight, failure to thrive in pregnancy, and adverse pregnancy outcomes". American Journal of ... However, in early pregnancy the outcome is worse, and can be fatal. Adequate nutrition is needed for a healthy fetus. Mothers ... Fergusson, David M.; Horwood, L. John; Northstone, Kate (2002). "Maternal use of cannabis and pregnancy outcome". BJOG: An ... Proietti, E (2013). "Air pollution during pregnancy and neonatal outcome: A review". Journal of Aerosol Medicine and Pulmonary ...
Fox C, Eichelberger K (2015). "Maternal microbiome and pregnancy outcomes". Fertility and Sterility. 104 (6): 1358-63. doi: ... While bacteria are often found in the amniotic fluid of failed pregnancies, they are also found in particulate matter that is ... Culturable and non-culturable bacterial species in the placenta obtained following normal term pregnancy have been identified. ... found in about 1% of healthy pregnancies. In non-human animals, part of the microbiome is passed onto offspring even before the ...
Ben-Haroush A, Yogev Y, Mashiach R, Meizner I. Pregnancy outcome of threatened abortion with subchorionic hematoma: possible ... "First-Trimester Intrauterine Hematoma and Outcome of Pregnancy". Obstetrics & Gynecology. 105 (2): 339-44. doi:10.1097/01.AOG. ... It occurs in about 3.1% of all pregnancies, it is the most common sonographic abnormality and the most common cause of first ... Hemorrhage During Pregnancy: Sonography and MR Imaging [3]. Amer J Roentgenology 2001; 176:607-615. Trop I, Levine D. ...
Harjulehto, T; Rahola, T; Suomela, M; Arvela, H; Saxén, L (1991). "Pregnancy outcome in Finland after the Chernobyl accident". ... the only robust evidence of negative pregnancy outcomes that transpired after the accident were these elective abortion ... In very high doses, it was known at the time that radiation could cause a physiological increase in the rate of pregnancy ... When the vast amount of pregnancy data does not support this perception as no women took part in the most radioactive ...
non-primary source needed]Shawky, S.; Milaat, W. (2000). "Early teenage marriage and subsequent pregnancy outcome" (PDF). ... School-age Pregnancy and Parenthood: Biosocial Dimensions. New York: Aldine De Gruyter. 1986. pp. 273-275. ISBN 978-0-202-30321 ... which would delay her menarche until after the end of the pregnancy. This goes against the widely held assumption that a woman ...
Olshan AF, Faustman EM (December 1989). "Nitrosatable drug exposure during pregnancy and adverse pregnancy outcome". Int J ... Medical history should in any case include questions about risk factors during pregnancy, the familial rate and the presence of ... Panchal J, Marsh JL, Park TS, Kaufman B, Pilgram T, Huang SH (May 1999). "Sagittal craniosynostosis outcome assessment for two ... Biomechanical factors include fetal head constraint during pregnancy. It has been found by Jacob et al. that constraint inside ...
... and number of transferred embryos are predictors of pregnancy outcome.[32] Ovarian tissue[edit]. Main article: Ovarian tissue ... One pregnancy and resulting healthy birth has been reported from an embryo stored for 27 years, after the successful pregnancy ... "Does storage time influence postthaw survival and pregnancy outcome? An analysis of 11,768 cryopreserved human embryos". ... Cryopreservation was applied to human materials beginning in 1954 with three pregnancies resulting from the insemination of ...
"Drinking Water Disinfection By-Products and Pregnancy Outcome" (PDF). Denver, CO: Awwa Research Foundation.. ... adverse birth outcomes and birth defects. Meta-analyses and pooled analyses of these studies have demonstrated consistent ...
"Subclinical Hypothyroidism and Pregnancy Outcomes". Obstetrics & Gynecology. 105 (2): 239-45. doi:10.1097/01.AOG. ... The pregnancy category levels (from least to most dangerous) are A, B, C, D and X and are described as follows: Category A: " ... Choline before pregnancy is also related to changes in the birth, death, and migration of cells in the hippocampus during the ... The pregnancy category level of cocaine is C, as described above. Prenatal exposure to cocaine has also been linked to ...
Fox, Chelsea; Eichelberger, Kacey (2015). "Maternal microbiome and pregnancy outcomes". Fertility and Sterility. 104 (6): 1358- ... It has been associated with the outcomes of assisted reproductive technologies and birth outcomes. Positive outcomes are ... The species and diversity of the microorganisms may be related to the various levels of hormones during pregnancy. The healthy ... to the presence of Lactobacilli spp while the presence of Propionibacterium and Actinomyces were related to negative outcomes. ...
Fox C, Eichelberger K (December 2015). "Maternal microbiome and pregnancy outcomes". Fertility and Sterility. 104 (6): 1358-63 ... the outcome is easily visualized and understood. Once a metagenome is assembled, it is possible to infer the functional ... improves behavioral outcomes) in certain central nervous system disorders - including anxiety, depression, autism spectrum ...
"Fludrocortisone Use During Pregnancy ,". Archived from the original on 24 December 2016. Retrieved 24 ... Actions and Outcomes. Springer Science & Business Media. pp. 21-. ISBN 978-3-7643-7726-7. Archived from the original on 5 ... Whether use of fludrocortisone during pregnancy is safe for the fetus is unknown. Fludrocortisone is mostly a mineralocorticoid ...
eds.). Multiple Pregnancy: Epidemiology, Gestation and Perinatal Outcome (1st ed.). New York: Taylor & Francis Group. pp. 41-2 ... A vanishing twin, also known as twin resorption, is a fetus in a multigestation pregnancy that dies in utero and is then ... Vanishing twins occur in up to one of every eight multifetus pregnancies and may not even be known in most cases. "High ... In pregnancies achieved by in vitro fertilization, "it frequently happens that more than one amniotic sac can be seen in early ...
Sue D. Nym, Ariosa is a Good Example of Outcome-Driven § 101 Decisions, IP Watchdog (Aug. 9, 2015). ... According to the patent, fetal DNA is from 0.39% of the sample (the lowest concentration measured in early pregnancy), to as ...
Glantz A, Marschall HU, Lammert F, Mattsson LA (December 2005). "Intrahepatic cholestasis of pregnancy: a randomized controlled ... "Efficacy, patient-reported outcomes and safety profile of ATX-101 (deoxycholic acid), an injectable drug for the reduction of ... primary sclerosing cholangitis or intrahepatic cholestasis of pregnancy.[23] Treatment with ursodeoxycholic acid has been used ... including types of cholestasis such as intrahepatic cholestasis of pregnancy, portosystemic shunt, and hepatic microvascular ...
Olshan AF, Faustman EM (December 1989). "Nitrosatable drug exposure during pregnancy and adverse pregnancy outcome". ... Biomechanical factors include fetal head constraint during pregnancy.[27] It has been found by Jacob et al. that constraint ... Medical history should in any case include questions about risk factors during pregnancy, the familial rate and the presence of ... Panchal J, Marsh JL, Park TS, Kaufman B, Pilgram T, Huang SH (May 1999). "Sagittal craniosynostosis outcome assessment for two ...
No major organization recommends universal screening for diabetes as there is no evidence that such a program improve outcomes. ... of islet cells in the pancreas and gestational diabetes that is a new onset of high blood sugars associated with pregnancy.[13] ... Rosiglitazone, a thiazolidinedione, has not been found to improve long-term outcomes even though it improves blood sugar levels ... Decreasing the systolic blood pressure to less than 140 mmHg is associated with a lower risk of death and better outcomes.[83] ...
In October 1854 Elinor was in labor, but the outcome was not happy. She gave birth to a stillborn baby and died herself shortly ... thereafter due to pregnancy complications. Jackson was devastated by grief but his faith supported him. The couple had been ...
neurological, psychological and other mental health outcomes. *Pregnancy. *Non-COVID-19-related health issues ...
"Oregon Study: Medicaid 'Had No Significant Effect' On Health Outcomes vs. Being Uninsured". Forbes. Retrieved April 18, 2019.. ... pregnancy, disability,[65] blindness, income and resources, and one's status as a U.S. citizen or a lawfully admitted immigrant ... In terms of self-reported health outcomes, having insurance was associated with an increased probability of reporting one's ... and some health outcomes, as well as economic benefits to states and health providers.[2][8] ...
Kaplan YC, Ozsarfati J, Etwel F, Nickel C, Nulman I, Koren G (November 2015). "Pregnancy outcomes following first-trimester ... Pregnancy[edit]. Although sebaceous gland activity in the skin increases during the late stages of pregnancy, pregnancy has not ... Pregnancy category refers to an evaluation of a substance's risk of injury to a fetus if used by the mother during pregnancy.[ ... the association between maternal topical retinoid exposure in the first trimester of pregnancy and adverse pregnancy outcomes ...
There is no difference in outcomes between embolization and ligation as treatment options, but embolization is considerably ... Pregnancy (rare, due to hypertension and hormonal changes). *Vascular disorders. *Vitamin C and vitamin K deficiency ...
Devkota, Bhimsen (1 December 2010). "Understanding effects of armed conflict on health outcomes: the case of Nepal". BioMed ... and only half of pregnant women take recommended iron supplementation during pregnancy. A contributing factor to deteriorating ... and only half of pregnant women take recommended iron supplementation during pregnancy. A contributing factor to deteriorating ...
This developing human is called an embryo for the first eight weeks of the pregnancy, and fetus for the rest of the pregnancy. ... "David M. Fergusson, Joseph M. Boden, L. John Horwood" (2007). ""Abortion Among Young Women and Subsequent Life Outcomes"". " ... "Early Pregnancy Loss (Miscarriage)". The Daily Telegraph. 2007. Retrieved 2007-07-20.. ... About forty percent of pregnancies are unplanned, and about a fifth of the pregnant women decide to end the pregnancy early. ...
Future research should focus on events that happen in pregnancy and labour that could be the cause of long term problems for ... CTG was associated with fewer neonatal seizures but it is unclear if it had any impact on long-term neurodevelopmental outcomes ... Cardiotocography (CTG) is a technical means of recording the fetal heartbeat and the uterine contractions during pregnancy. The ... there is no evidence to suggest that monitoring women with high-risk pregnancies benefits the mother or baby although research ...
... due to perceived better outcomes and more pregnancies carried to term. A c-section is required for women giving birth with a ... Usually the treatment is done in the second trimester of pregnancy, for a woman who had either one or more late miscarriages in ... The treatment consists of a strong suture being inserted into and around the cervix early in the pregnancy, usually between ... This cerclage is usually placed between 16 weeks and 18 weeks of pregnancy. The stitch is generally removed around the 37th ...
Though there is limited evidence, outcomes appear to be relatively poor with a review of outcome studies finding that two ... the authors point out ways in which this may have biased their outcome data. Outcome was shown to be better in people with ... McDade G, Brown SW (March 1992). "Non-epileptic seizures: management and predictive factors of outcome". Seizure. 1 (1): 7-10. ... ReACT, while new and understudied, has shown extremely promising outcomes for reduction of PNES episodes in pediatric patients. ...
... the evidence that smoking bans improved health outcomes had become more robust, especially with respect to acute coronary ... are viewed by public health experts as an important element in reducing smoking rates and promoting positive health outcomes. ...
There is a wide range of ways to measure treatment outcomes.[90] Chiropractic care, like all medical treatment, benefits from ... or pelvic and back pain during pregnancy.[135] As there is no evidence of effectiveness or safety for cervical manipulation for ... Khorsan R, Coulter ID, Hawk C, Choate CG (June 2008). "Measures in chiropractic research: choosing patient-based outcome ... "Interventions for preventing and treating low-back and pelvic pain during pregnancy". The Cochrane Database of Systematic ...
Gandara, E.; Bose, G.; Erkens, P.; Rodgers, M.; Carrier, M.; Wells, P. (April 4, 2011). "Outcomes of saddle pulmonary embolism ... High levels of estrogen because of pregnancy or some birth control pills ...
"A prospective study of maternal and fetal outcome in acute Lassa fever infection during pregnancy". BMJ. 297 (6648): 584-7. doi ...
... to provide information on outcomes of this biennial event to future World Health Assembly meetings.[citation needed] ... and highlighting that the numbers of women dying in pregnancy and childbirth were still the same 14 years later.[13] ...
See also: Transgender pregnancy, Uterus transplantation § Application on transgender women, and Male pregnancy § Humans ... Many patients perceive the outcome of the surgery as not only medically but also psychologically important. Social support can ... Sex reassignment surgery performed on unconsenting minors (babies and children) may result in catastrophic outcomes (including ... it has been suggested that most studies investigating the outcomes of sex reassignment surgery are flawed as they have only ...
Pregnancy and lactation[edit]. The doses of moclobemide in breast milk are very low (0.06% of moclobemide being recovered in ... Versiani M, Amrein R, Montgomery SA (September 1997). "Social phobia: long-term treatment outcome and prediction of response--a ...
Tammy Duckworth's Pregnancy Set To Be Another First for the Illinois Democrat". NPR. Archived from the original on 4 February ... These seven "desired student learning outcomes," or DSLOs, include content knowledge, cultural competence, character, ...
Various hypotheses have been proposed, in attempts to explain why early life adversity can produce outcomes ranging from ... For example, several studies have found an association between maternal depression during pregnancy and childhood cortisol ... This mismatch may then predict negative developmental outcomes such as psychopathologies in later life. ... adaptations through pregnancy and lactation". Stress. 8 (1): 5-18. doi:10.1080/10253890500044380. PMID 16019594.. ...
Childhood blindness can be caused by conditions related to pregnancy, such as congenital rubella syndrome and retinopathy of ... with the variant outcomes as well as the unequal access to cataract surgery, the best way to reduce the risk of developing ...
Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomised evidence. BMJ ( ... Arendas K, Qiu Q, Gruslin A. Obesity in pregnancy: pre-conceptional to postpartum consequences. Journal of Obstetrics and ... Results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation ... systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54). BMJ (Clinical ...
... from measurement and planning to performance for improved health outcomes. Archived 2015-09-24 at the Wayback Machine Human ... during and after pregnancy and childbirth. Such health practitioners include obstetricians, physician assistants, midwives, ... are the primary source of pregnancy and childbirth care for many women and families, although they are not certified or ... pregnancy and childbirth care, surgical care, rehabilitation care, or public health. ...
... myopia act in a risky manner because of the myopia's inhibiting effects on their ability to analyze the probable outcomes of ... activates dopaminergic circuits in the midbrain that also regulate the brain's analyzation and recognition of the outcomes of ...
Chaudhry SA, Gad N, Koren G «Toxoplasmosis and pregnancy» (en anglès). Can Fam Physician, 2014 Abr; 60 (4), pp: 334-336. ISSN: ... Aleixo AL, Curi AL, Benchimol EI, Amendoeira MR «Toxoplasmic Retinochoroiditis: Clinical Characteristics and Visual Outcome in ... Lopes FM, Gonçalves DD, Mitsuka-Breganó R, Freire RL, Navarro IT «Toxoplasma gondii infection in pregnancy» (en anglès). Braz J ...
For each month between pregnancies longer than five years, the risk for these adverse outcomes increased by 0.6% to 0.9%. ... All of the studies included in the analysis attempted to account for known influences on pregnancy outcomes, including maternal ... optimizing the nutritionnutrition she provides that baby and lowering her risk of having an adverse pregnancypregnancy outcome ... Although timing may not be everything, the analysis suggests that better pregnancypregnancy spacing could have a dramatic ...
Does air travel affect pregnancy outcome?. Freeman M1, Ghidini A, Spong CY, Tchabo N, Bannon PZ, Pezzullo JC. ... Pregnancy outcome was obtained by chart review. Statistical analysis included Students t-test, Mann-Whitney U test, chi square ... 16%, p=0.56), or cumulative adverse obstetric outcome ( p=0.61) between those who did and did not air travel during pregnancy. ... To evaluate if air travel affects pregnancy outcome, all women with singleton, non anomalous fetuses, admitted for delivery at ...
Pregnancy outcome in carriers of Robertsonian translocations.. Keymolen K1, Van Berkel K, Vorsselmans A, Staessen C, Liebaers I ... When considering all pregnancies involving carriers, 52.7% of those to female carriers and 61.8% of those to male carriers led ... More than half of the pregnancies led to the birth of a healthy child, but prediction of which couples will be successful in ... Data on the carriers and the results of their prenatal analyses were retrieved as well as data on their previous pregnancies. ...
Environmental contaminants and pregnancy outcomes. (2008). *Pregnancy outcomes, infant mortality, and arsenic in drinking water ... Pregnancy and Birth Outcome Research. We focus on the woman and infants health during and after pregnancy, with special ... Exposure to organic solvents and adverse pregnancy outcome. (1991). *Use of video display terminals during pregnancy and the ... Adverse pregnancy outcomes in relation to water consumption: a re-analysis of data from the original Santa Clara County Study, ...
... Isr Med Assoc J. 2000 Jan;2(1):10-3. ... Objectives: To describe the distribution of weight in pregnant women and evaluate the influence of obesity on pregnancy outcome ... Results: Obese mothers had a higher incidence of gestational diabetes and pregnancy-induced hypertension compared to normal ...
"This study highlights the importance of crashes during pregnancy and their possible adverse effects on pregnancy outcomes. ... Recording pregnancy outcomes. The study, which is the largest retrospective state-based study of its kind, looked at data for ... "Adverse Pregnancy Outcomes Following Motor Vehicle Crashes," by Catherine J. Vladutiu, PhD et al.; Published online 8 October ... "Car crashes linked to adverse pregnancy outcomes." Medical News Today. MediLexicon, Intl., 8 Oct. 2013. Web.. 24 Jun. 2019. , ...
Preconception Significance: Adverse pregnancy outcomes are of significance because adverse previous pregnancy outcomes are ... Patient is (PIC)turing Pregnancy - Previous Pregnancy Outcomes. Background * Scope: Ohio presents many areas of concern related ... Review obstetric history annually in order to easily spot adverse conditions and pregnancy outcomes including: ... most risky period in the first 5 years after pregnancy. Provider should screen after pregnancy with 2 hour GTT and rescreen ...
Review information below for women who have questions on future pregnancy outcomes based on previous pregnancy outcomes. ... Preconception Significance: Adverse pregnancy outcomes are of significance because adverse previous pregnancy outcomes are ... Patient is Not (PIC)turing Pregnancy - Previous Pregnancy Outcomes. Background * Scope: Ohio presents many areas of concern ... Review obstetric history annually in order to easily spot adverse conditions and pregnancy outcomes including: ...
Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Associations of maternal A1C and glucose with pregnancy outcomes. ... The objective of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study was to clarify the risk of adverse outcomes ... Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Lynn P. Lowe, Boyd E. Metzger, Alan R. Dyer, Julia Lowe, David R. ... Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Lynn P. Lowe, Boyd E. Metzger, Alan R. Dyer, Julia Lowe, David R. ...
... Seda Ates,1,2 Gonca Batmaz,1 Osman Sevket,1 Taner Molla,1 Cem Dane,3 ... Seda Ates, Gonca Batmaz, Osman Sevket, Taner Molla, Cem Dane, and Banu Dane, "Pregnancy Outcome of Multiparous Women Aged over ...
Cite this: WIN-TAVI: Even Remote History of Pregnancy Predicts Better TAVI Outcomes - Medscape - May 18, 2016. ... History of pregnancy was associated with a lower rate of the 30-day primary safety end point of all-cause mortality, stroke, ... In all, 72.4% of the 1019 women in the study had a history of pregnancy, defined simply as yes or no and not whether it ... PARIS, FRANCE - Having a history of pregnancy even decades earlier was protective against complications in women at ...
... surveillance programmes should aim to ascertain congenital anomalies among all pregnancy outcomes, with the exception of early ... Inclusion of pregnancy outcomes is dependent on a countrys ability and resources to detect all or most outcomes. In some ... Pregnancy outcome (live births, stillbirths and termination of pregnancies. for fetal anomaly) ... Including as many types of pregnancy outcomes as possible improves case detection. Inclusion of live births alone is a ...
Distribution of pregnancy outcomes among ascertained spina bifida cases, 2007-2009. resize iconView Larger ... Distribution of pregnancy outcomes among ascertained anencephaly cases, 2007-2009. resize iconView Larger ... 3.14 show how inclusion of the different types of pregnancy outcomes has improved case ascertainment for anencephaly and spina ... Surveillance programmes aim to ascertain congenital anomalies among all pregnancy outcomes - live births, fetal deaths and ...
PubMed journal article Hyperglycemia and adverse pregnancy outcome were found in PRIME PubMed. Download Prime PubMed App to ... Pregnancy. Pregnancy Complications. Pregnancy Outcome. Pub Type(s). Journal Article. Multicenter Study. Research Support, N.I.H ... Hyperglycemia and adverse pregnancy outcome study: neonatal glycemia.. *The hyperglycemia and adverse pregnancy outcome study: ... Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: associations of maternal A1C and glucose with pregnancy outcomes. ...
VENNERI MATHIAS, Cícero et al. Foscarnet Effects on the Rat Pregnancy Outcome . Int. J. Morphol. [online]. 2005, vol.23, n.2, ... The aim of this study was to evaluate the effects of foscarnet on the entire period of rat pregnancy. Female pregnant rats were ... There are few long-term data on which to base decisions of drug management of HIV infection in pregnancy. The determination of ... The treatment period extended from the first until the 20th day of pregnancy. Body weights were recorded weekly along this ...
Mothers who were overweight at the start of pregnancy had the fewest fetal and neonatal deaths with a 16 pound weight gain at ... This study determined the relationship of maternal weight gain in pregnancy to its outcome. ... Weight gain and the outcome of pregnancy Am J Obstet Gynecol. 1979 Sep 1;135(1):3-9. ... This study determined the relationship of maternal weight gain in pregnancy to its outcome. Mothers who were overweight at the ...
... embryo development and pregnancy outcome in the human. The role that the spermatozoon plays, however, has not... ... Association between human in vitro fertilization rate and pregnancy outcome: a possible involvement of spermatozoal quality in ... effects on pregnancy outcome and the male reproductive and hematologic systems. Biol Reprod 1987;37:317-26.Google Scholar ... and Pregnancy Outcome. In: Gardner D.K., Lane M. (eds) ART and the Human Blastocyst. Proceedings in the Serono Symposia USA ...
Placenta plays pivotal "umpire" role to influence pregnancy outcomes. Published Tuesday 13 September 2016 Published Tue 13 Sep ... "Placenta plays pivotal "umpire" role to influence pregnancy outcomes." Medical News Today. MediLexicon, Intl., 13 Sep. 2016. ... 2016, September 13). "Placenta plays pivotal "umpire" role to influence pregnancy outcomes." Medical News Today. Retrieved from ... in particular to see if there are specific factors that we can change to improve the outcome of pregnancies. Being able to ...
Maternal Tdap vaccination during pregnancy isnt associated with adverse outcomes for offspring through early childhood, a new ... Tdap in Pregnancy Not Tied to Childhood Adverse Outcomes * Pertactin-Deficient Bordetella pertussis, Vaccine-Driven Evolution, ... vaccination during pregnancy isnt associated with adverse outcomes for offspring through early childhood, a new study suggests ... Some adverse outcomes were significantly lower among Tdap-exposed infants than among unexposed infants, the authors note. ...
Sanitation practices such as open defecation are associated with an elevated risk of adverse birth outcomes in rural India, ... The study, recently published in PLOS Medicine, provides insight on how pregnancy outcomes compare for women who use a latrine ... Open defecation as well as other poor WASH practices can lead to adverse pregnancy outcomes for several reasons. First, poor ... Ultimately, Panigrahi aims to create an improved environment to support better pregnancy outcomes to improve the next ...
The objective of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study was to clarify the risk of adverse outcome ... HAPO Study Cooperative Research Group: The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Intl J Gyn Ob.78 :69 -77, ... HAPO Study Cooperative Research Group: Hyperglycemia and adverse pregnancy outcomes. N Engl J Med358 :1991 -2002,2008. ... experience from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Clin Trials3 :397 -407,2006. ...
Some may have questions about avoiding a pregnancy ... Time to achieve pregnancy affects outcomeSome people have basic ... The time needed to achieve pregnancy appears to affect the outcome of that pregnancy, Swedish researchers report. In particular ... studies that have compared the time to pregnancy with pregnancies ending in live births to the rate of pregnancies outside of ... Among pregnancies ending in a single live birth, the time to pregnancy was directly linked to the risk of preterm delivery, the ...
The aim of our study was to assess the prevalence and outcome of pregnancy in idiopathic inflammatory myopathy patients who ... The aim of our study was to assess the prevalence and outcome of pregnancy in idiopathic inflammatory myopathy patients who ... 3712863 - Pregnancy and penicillamine treatment in a patient with wilsons disease.. 17175503 - Term pregnancy at the site of ... Nine patients with pregnancies after the disease onset had 14 gravidities. Six pregnancies resulted in normal deliveries, two ...
Adverse pregnancy outcomes, including preeclampsia, preterm delivery, and intrauterine growth restriction, and fetal demise ... This chapter highlights the two-way relationship between periodontitis and adverse pregnancy outcome. ... affect a significant number of pregnancies and are a major source of both maternal and neonatal morbidity and mortality. ... Attempts to improve oral health in women during pregnancy have not reduced adverse pregnancy outcome (APO). No reduction in ...
... improved pregnancy outcomes via early detection (IMPROvED). BMC Pregnancy Childbirth. 2013 Dec 7;13:226. doi: 10.1186/1471-2393 ... IMproved PRegnancy Outcome by Early Detection (IMPROvED). The safety and scientific validity of this study is the ... Secondary Outcome Measures : *Early onset pre-eclampsia [ Time Frame: Followed for the duration of hospital stay, an expected ... Primary Outcome Measures : *Pre-eclampsia. [ Time Frame: 7 days after birth ]. Preeclampsia is defined as gestational ...
... improved pregnancy outcomes via early detection (IMPROvED). BMC Pregnancy Childbirth. 2013 Dec 7;13:226. doi: 10.1186/1471-2393 ... IMproved PRegnancy Outcome by Early Detection (IMPROvED). This study is currently recruiting participants. See Contacts and ... Secondary Outcome Measures: *Early onset pre-eclampsia [ Time Frame: Followed for the duration of hospital stay, an expected ... Pregnancies affected by severe maternal or severe fetal or neonatal complications (as defined in Major neonatal morbidity in ...
Preventing early pregnancy and poor reproductive outcomes among adolescents in developing countries : a call to action  World ... Toumba, M., Kanaris, C., Simamonian, K. & Skordis, N. (‎2008)‎. Outcome and management of pregnancy in women with thalassaemia ... We describe the management and clinical outcome of pregnancies among 100 Greek Cypriot women with thalassaemia: 88 with ... Multiple successful pregnancies included 7 twins and 1 triple pregnancy. Pregnant thalassaemics required significantly larger ...
Traffic pollution is linked to poor pregnancy outcomes BMJ 2017; 359 :j5511 ... Traffic pollution is linked to poor pregnancy outcomes. BMJ 2017; 359 doi: (Published 05 ... Small particle pollution exposure in pregnancy has previously been linked to fetal growth,3 as well as preterm birth,4 ... The association between air pollution, pregnancy complications, and childhood illness is not new. ...
Learn more about the Pregnancy and Cardiovascular Outcomes Registry at Fairview Hospital. Download the brochure for more ... Pregnancy & Cardiovascular Outcomes Registry. Physicians are interested in whether or not certain high-risk pregnancies are ... Home / Find a Location / Fairview Hospital / Specialties / Birthing Services / Pregnancy & Cardiovascular Outcomes Registry ...
The procedure prolonged pregnancy in all the patients with the mean duration of 38 days. The outcome for emergency cerclage was ... However, the outcome for emergency cerclage is less favourable. Methodology: A retrospective analysis of the case notes of ... Conclusion: Favourable outcomes should be expected in carefully selected cases and all patients should be informed of the ... 3 stillbirths (IUFD) and 7 live births (6 survived with 1 early neonatal death). Neonatal outcome was good if the initial ...
  • Women who have experienced a stillbirth or neonatal death are at higher risk of repeated poor neonatal outcomes if they have short interpregnancy intervals. (
  • medical administrations including magnesium sulfate, dexamethasone and bricanyl, outcome of deliveries and neonatal outcomes, were different with statistical significance between the 3 groups of pregnant women. (
  • Conclusion: Adverse maternal and neonatal outcomes were mostly found in the pregnant women ≤ 16 and ≥ 40 years. (
  • Each 5-kg incremental weight change in the first pregnancy, interpregnancy, and second pregnancy contributed to a 0.75- to 5-kg weight change in subsequent periods, 9% to 25% change in risk for adverse maternal outcomes, and 8% to 47% change in risk for adverse neonatal outcomes in the second pregnancy. (
  • 2 There are few prospective studies of the effect of antenatal vaccination against influenza on fetal and neonatal outcomes. (
  • CONTINUING to use cannabis during pregnancy is an independent risk factor for poorer neonatal outcomes, according to the authors of research published by the Medical Journal of Australia today. (
  • Continued and high frequency of cannabis use during pregnancy were each associated with significantly poorer neonatal outcomes," Grzeskowiak and colleagues concluded. (
  • Women with PCOS and hyperandrogenism and impaired glucose regulation prior to pregnancy should be more closely monitored during pregnancy and may require additional interventions to prevent adverse obstetric and neonatal outcomes . (
  • report on a small, observational trial that showed a dramatic improvement in both maternal and fetal/neonatal outcomes in women with APS given pravastatin after the onset of preeclampsia and/or IUGR compared with women in the control group. (
  • Although timing may not be everything, the analysis suggests that better pregnancy pregnancy spacing could have a dramatic impact on neonatal complications and deaths, both worldwide and in the United States. (
  • 20.0 weeks over a 6-month period were asked if they traveled by airflight during pregnancy, including details of the destination and length of their flights and any complications during the travel. (
  • Our findings suggest that air travel is not associated with increased risk of complications for pregnancies that reach 20 weeks' gestation. (
  • Women's heath complications pose very significant risks to the pregnancy and infant, as well as life-long illness. (
  • Maternal complications can predict the development of chronic illness that could impact her health, future pregnancies, and children. (
  • Historically, A1C concentrations in preexisting diabetes have been associated with the risk of chronic complications and of adverse events during pregnancy, such as miscarriage, congenital malformations, or macrosomia ( 3 ). (
  • A better understanding of how the placenta manages the trade-off will eventually enable researchers to reduce pregnancy complications in both humans and other mammals. (
  • The study was led by Dr Amanda Sferruzzi-Perri, a Research Associate at St John's College, University of Cambridge, and is part of a five-year project in the Department of Physiology, Development and Neuroscience examining the relationship between the placenta and pregnancy complications. (
  • If nutrients cannot be divided correctly during pregnancy, it can lead to life-threatening complications for expectant mothers, and long-term health consequences for both mother and child. (
  • At least one in every eight pregnancies in the UK is affected by complications stemming from impairment of the placenta. (
  • The association between air pollution, pregnancy complications, and childhood illness is not new. (
  • Tommy's funds research across the UK investigating the reasons for pregnancy complications and loss. (
  • The society is devoted to reducing high-risk pregnancy complications by providing continuing education to its 2,000 members on the latest pregnancy assessment and treatment methods. (
  • Every year, many women suffer pregnancy-related complications and a number die. (
  • Due to the routine practice of transferring two embryos during an IVF cycle, women undergoing this treatment face an increased risk of twin pregnancy and associated complications (e.g. premature delivery, perinatal death). (
  • But researchers from Marquette University and the University of Michigan found that among normal-weight women, fluctuating weight gain and loss in the first pregnancy is often repeated in subsequent pregnancies--and is associated with higher risk of several pregnancy-related complications. (
  • These women often share the same pregnancy complications as women with type 2 diabetes and obesity. (
  • Dr. Joel Ray and coauthors tested whether this "healthy immigrant effect" extends to complications during pregnancy. (
  • Multiple pregnancies have a higher risk of complications for women and their babies than do single pregnancies. (
  • The focus of this unit is the two most common nutrition-related pregnancy complications: obesity and gestational diabetes mellitus. (
  • Based on the latest scientific findings the learner will gain an in-depth knowledge of the risk factors, outcomes and recommendations associated with these pregnancy complications to better manage and counsel pregnant women and improve infant outcomes. (
  • However, the methods for screening the low risk population for other complications of pregnancy such as fetal growth restriction (FGR), pre-eclampsia and stillbirth have remained largely unchanged for the past 20-30 years. (
  • The types of samples collected during the POP study reflect, first of all, the focus on the role of the placenta and its altered development and function in several major complications of pregnancy. (
  • The most comprehensive study, published 20 years ago, documented a high incidence of obstetric complications, including toxaemia of pregnancy, premature delivery, low birth weight, and a high caesarean section rate, 13 but a recent case report noted spontaneous resolution of AIH during pregnancy. (
  • Investigators focused on four pregnancy outcomes: preterm birth, placental abruption (where the placental lining becomes separated from the uterus), premature rupture of the membranes (which can bring on labor) and stillbirth. (
  • No relationship was seen between time to pregnancy and stillbirth. (
  • Small particle pollution exposure in pregnancy has previously been linked to fetal growth, 3 as well as preterm birth, 4 stillbirth, 5 and respiratory morbidity in children. (
  • Investigators focused on four pregnancy outcomes: preterm birth, placental abruption, premature rupture of the membranes, and stillbirth. (
  • Daily use of snus during pregnancy is associated with increased risk of preterm delivery, stillbirth and neonatal apnea. (
  • Some of the outcomes are rare, such as stillbirth, and it is desirable to have as high a precision as possible. (
  • In all, 72.4% of the 1019 women in the study had a history of pregnancy, defined simply as 'yes' or 'no' and not whether it ended in a live birth, according to the data reported at EuroPCR 2016 and simultaneously published online in JACC: Cardiovascular Interventions . (
  • Cite this: WIN-TAVI: Even Remote History of Pregnancy Predicts Better TAVI Outcomes - Medscape - May 18, 2016. (
  • In fact, the 2016 March of Dimes Premature Birth Report Card reported the rate of pre-term pregnancies in the United States is on the rise again for the first time in eight years . (
  • This study, which included 3894 women who gave birth between 1 January and 31 December 2016, analysed singleton pregnancies at Cwm Taf University Health Board. (
  • We thought the laborist model would improve pregnancy outcomes and now we have data that demonstrates that," said Srinivas. (
  • It concludes with cross-cutting themes and action items that stakeholders across the continuum of perinatal care will recognize as opportunities to improve pregnancy outcomes. (
  • A new study has revealed that a commonly prescribed anti-diabetes drug, Metformin, can potentially improve pregnancy outcomes in women having insulin resistance. (
  • Group prenatal care can improve pregnancy outcomes in the area of reducing preterm births and increasing breastfeeding initiation, psychosocial function, and patient satisfaction. (
  • For example, a woman with preeclampsia/eclampsia, has a 1.4 -3.98 risk of developing chronic hypertension after pregnancy. (
  • Secondary outcomes were delivery before 37 weeks of gestation, shoulder dystocia or birth injury, need for intensive neonatal care, hyperbilirubinemia, and preeclampsia. (
  • Adverse pregnancy outcomes, including preeclampsia, preterm delivery, and intrauterine growth restriction, and fetal demise affect a significant number of pregnancies and are a major source of both maternal and neonatal morbidity and mortality. (
  • The overall objective of the IMPROvED project is to develop a sensitive, specific, high-throughput and economically viable early pregnancy screening test for preeclampsia. (
  • Gestational diabetes mellitus (GDM) and hypertensive conditions in pregnancy such as gestational hypertension and preeclampsia both occur at elevated rates in women of certain ethnicities. (
  • In moms, the researchers looked at the incidence of gestational diabetes and preeclampsia (dangerously high blood pressure during pregnancy). (
  • 21:772-778.Wikstrom AK, Stephansson O and Cnattingius S Tobacco use during pregnancy and preeclampsia risk. (
  • Researchers assessed incidence of preeclampsia, preterm delivery, infants born small for gestational age, low Apgar score and any adverse outcome, using linked data from the Dutch perinatal national registry. (
  • Among recorded obstetric outcomes, 4% of women developed preeclampsia and 10% delivered preterm, whereas 9% of infants were born small for gestational age and 3% of children had an Apgar score of 7 or lower, according to researchers. (
  • Obesity is a risk factor for pregnancy-induced hypertension, preeclampsia, gestational diabetes, and large gestational age pregnancy. (
  • Changes in TNFα and its receptors are associated with adverse pregnancy outcomes, including miscarriage, preterm labor and preeclampsia. (
  • We focus on the woman and infant's health during and after pregnancy, with special attention to environmental factors that are associated with these health outcomes. (
  • We wouldn't expect to see any association between vaccination and health outcomes in children," said Dr. Annette Regan, an assistant professor at the University of San Francisco who wasn't involved in the study. (
  • Delivering positive health outcomes means proactively reaching out to communities, expanding access to education, and connecting expectant mothers with the care they need," concluded Darnell Dent, President & CEO of FirstCare. (
  • Researchers found that infants born to women who conceived less than six months after giving birth had a 40% increased risk for being born prematurely and a 61% increased risk of low birth weight, compared with infants born to mothers who waited 18 months to two years between pregnancies. (
  • She adds that in the United States between 6% and 10% of pregnancies among women who have already given birth occur less than six months after childbirth . (
  • So women who follow recommendations to breastfeed exclusively for at least the first six months of her baby's life would be both optimizing the nutrition nutrition she provides that baby and lowering her risk of having an adverse pregnancy pregnancy outcome the next time she gives birth. (
  • Power analysis demonstrated that a sample size of 2,803 women in each group would be necessary to show that air travel has a protective effect against adverse pregnancy outcome (alpha = 0.05, beta = 0.80). (
  • To describe the distribution of weight in pregnant women and evaluate the influence of obesity on pregnancy outcome in a high parity northern Israeli population. (
  • Clinicians should be aware of these effects and should advise pregnant women about the risk of being in a crash and the long-term consequences that crashes can have on their pregnancies. (
  • While previous studies had only looked at the link between one crash and adverse pregnancy outcomes, this new study also looked at women who had been involved in multiple motor vehicle collisions during their pregnancies. (
  • Review information below for women who have questions on future pregnancy outcomes based on previous pregnancy outcomes. (
  • OBJECTIVE To compare associations of maternal glucose and A1C with adverse outcomes in the multinational Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study and determine, based on those comparisons, if A1C measurement can provide an alternative to an oral glucose tolerance test (OGTT) in pregnant women. (
  • CONCLUSIONS On the basis of associations with adverse outcomes, these findings suggest that A1C measurement is not a useful alternative to an OGTT in pregnant women. (
  • However, it has been shown that A1C measurements ( 4 , 5 ) and fructosamine levels ( 6 , 7 ) do not adequately separate women with normal pregnancy from those with gestational diabetes mellitus (GDM), even though A1C levels decline in normal pregnancy ( 8 ). (
  • Notably, only 31 women reported having a pregnancy-related complication, either gestational diabetes or hypertension. (
  • If terminations are not legal, will women go to another country to terminate a pregnancy? (
  • Concerns about safety is one of the key reasons that women cite for not getting vaccinated with Tdap or influenza vaccine during pregnancy, so this study can help provide additional reassurance to what we already know about safety of maternal immunization," Fell said by email. (
  • The study , recently published in PLOS Medicine, provides insight on how pregnancy outcomes compare for women who use a latrine verses those who defecate in the open. (
  • Many young and pregnant women are using e-cigarettes as a safer alternative to smoking, but little is known about the effects on fertility and pregnancy outcomes. (
  • The findings, which appear in the journal Fertility and Sterility, are based on a study of 5,302 pregnancies in three Swedish groups of women. (
  • The women were surveyed to determine the time to pregnancy . (
  • Personalized Medicine for Pregnant Women: Novel Metabolomic and Proteomic Biomarkers to Detect Pre-eclampsia and Improve Outcome. (
  • We describe the management and clinical outcome of pregnancies among 100 Greek Cypriot women with thalassaemia: 88 with thalassaemia major and 12 with thalassaemia intermedia. (
  • Background: The pregnancy outcome following cervical cerclage for women with cervical incompetence is generally favourable. (
  • The aim of this cross-sectional hospital-based study of 7,845 pregnancies was to analyze deaths of women hospitalized for childbirth and abortion, and fetal and neonatal deaths, in public hospitals in. (
  • Could something as simple as taking a low-dose aspirin once a day guard against pregnancy loss among women who have already suffered miscarriages? (
  • The new findings run counter to a previous analysis of the same data, which found no difference in pregnancy loss among women who took aspirin or dummy pill while trying to conceive . (
  • Aspirin in this group of women could play an important role in reducing risk of pregnancy loss, but they have to stick with the regimen,' Naimi said. (
  • The beneficial effect of aspirin was stronger if women began taking it before pregnancy and weaker if they started taking it after the sixth week of gestation,' he explained. (
  • In absence of published hospital data regarding pregnancy outcomes, pregnant people and particularly Black women in New York State, cannot make informed decisions about where to receive their care or whether their local hospital is a safe place for them to birth their babies. (
  • We use data from the Indonesia Family Life Survey to investigate the impact of a major expansion in access to midwifery services on health and pregnancy outcomes for women of reproductive age. (
  • Women of different ethnicities also experience higher rates of adverse pregnancy outcomes and interventions including preterm birth, low birth weight/small for gestational age, and cesarean birth. (
  • Ethnicity modifies the effect of obesity on insulin resistance in pregnancy: a comparison of Asian, South Asian, and Caucasian women. (
  • This study indicates that researchers can now identify if women who may be at risk for an adverse pregnancy associated with lupus. (
  • In industrialized countries, recommendations do exist regarding the use of highly active antiretroviral treatment throughout pregnancy of HIV positive women. (
  • Objective: To study the adverse outcome in pregnant women ≤ 16 and ≥ 40 years. (
  • However, new research findings suggest the timing of the operation may increase the risk of adverse outcomes for pregnant women. (
  • Women who have their gallbladder removed during pregnancy are more likely to experience longer hospital stays, increased 30-day readmissions, and higher rates of preterm delivery than those who delay the operation until after childbirth, according to the study results published online as an " article in press " on the Journal of the American College of Surgeons website in advance of print publication. (
  • In light of these findings, whenever possible, women with symptomatic gallstones in pregnancy should wait as long as possible to let the baby mature before having the cholecystectomy," said study coauthor Henry A. Pitt, MD, FACS, professor of surgery at Temple University School of Medicine, Philadelphia. (
  • Additionally, the hemorrhage and preterm delivery rates for women who had the cholecystectomy during pregnancy was 3 percent and 12 percent higher, respectively. (
  • The researchers found that women who underwent the operation during the third trimester were twice as likely to deliver a preterm baby and almost twice as likely to have abnormal maternal outcomes. (
  • Women who postponed the cholecystectomy until after childbirth had better maternal outcomes. (
  • To examine pregnancy and birth outcomes among women with idiopathic thrombocytopenic purpura (ITP) or chronic ITP (cITP) diagnosed before or during pregnancy. (
  • A linkage of mothers and babies within a large US health insurance database that combines enrollment data, pharmacy claims, and medical claims was carried out to identify pregnancies in women with ITP or cITP. (
  • Among 446 pregnancies in women with ITP, 346 resulted in live births. (
  • Women with cITP experienced more adverse outcomes than those with a pregnancy-related diagnosis of ITP. (
  • Unfortunately, at-risk expectant women often seek care later in their pregnancies, missing the window for vital prenatal care and treatment. (
  • Beetroot juice can reduce blood pressure in pregnancy: can we predict which women will respond? (
  • New research has indicated that pregnant women with pre-gestational diabetes who take metformin are at a higher risk for adverse pregnancy outcomes than the general population. (
  • The researchers evaluated the risk of major birth defects and pregnancy losses in a cohort of pregnant women exposed to metformin during first trimester for different indications relative to a matched unexposed reference group. (
  • The risk of pregnancy losses (miscarriages and stillbirths) was 20.8% in women on metformin during the first trimester and 10.8% in the reference group. (
  • Fluctuations in weight across pregnancies and associations with outcomes were strongest among normal-weight and overweight women. (
  • the larger weight fluctuations observed in normal and overweight women were associated with greater risk of adverse outcomes. (
  • 1 - 4 In the United States, ∼1% of pregnant women use drugs for treatment of ADHD, which ranks these medications among the most commonly used prescription drugs during pregnancy. (
  • Boston) - Results of a pilot study suggest that a virtual patient advocate (VPA) could help influence positive changes and help women have healthier pregnancies. (
  • The study results, which are published online in the American Journal of Health Promotion , suggest that Gabby could help identify risk factors and influence positive changes in women before they conceive and decrease the risk for adverse birth outcomes. (
  • New research indicates that pregnant women with pre-gestational diabetes who take metformin are at a higher risk for adverse pregnancy outcomes--such as major birth defects and pregnancy loss--than the general population, but their increased risk is not due to metformin but diabetes. (
  • To compare labour and delivery outcomes in women undergoing induction and those having spontaneous onset for pregnancies past the estimated date of delivery, a prospective study of 395 singleton, uncomplicated pregnancies was performed. (
  • Halle C.F. Moore, M.D., from the Cleveland Clinic Foundation, and colleagues examined long-term pregnancy and disease-related outcomes for patients in S0230/POEMS, which enrolled premenopausal women with stage I to IIIA estrogen receptor-negative, progesterone receptor-negative breast cancer. (
  • The association between tobacco use and pregnancy outcomes has been investigated in a recently publish cohort study comprising women who used snus or smoked daily and a control who didn't use tobacco. (
  • Swedish Match recommends that women abstain from snus and other sources of nicotine during pregnancy. (
  • 2003) used data from the Swedish Medical Birth Register to compare the birth outcomes of 789 women who used snus daily, 11240 women who smoked cigarettes daily and 11495 women who used no tobacco products. (
  • A systematic review published in The Cochrane Library suggests that maternity care that involves a midwife as the main care provider leads to better outcomes for most women. (
  • Researchers found that women who received continued care throughout pregnancy and birth from a small group of midwives were less likely to give birth pre-term and required fewer interventions during labour and birth than when their care was shared between different obstetricians, GPs and midwives. (
  • In many countries, including the UK and Australia, midwives act as the main providers of care for women throughout pregnancy, labour and birth. (
  • Women taking antidepressants during pregnancy were more likely to have babies who required neonatal unit admission, a study has found. (
  • A team of researchers from Australia, the UK and New Zealand, analysed data from 5610 pregnant nulliparous women with low risk pregnancies, recruited for the Screening for Pregnancy Endpoints (SCOPE) study, November 2004 - February 2011. (
  • At 14-16 weeks of pregnancy, women were grouped by self-reported cannabis use. (
  • The differences for all outcomes except gestational age were greater for women who used cannabis more than once a week than for those who used it less frequently. (
  • These findings could reflect the lower gestational age at birth for babies of women who continue using cannabis during pregnancy or be related to altered fetal growth. (
  • Our findings provide important information for women and health care providers about the potential harms of cannabis use during pregnancy, which is particularly important given the increasing perception in the community that cannabis is a safe drug. (
  • Eating disorders are relatively common among women of reproductive age, yet the literature on the effects of maternal eating disorders (ED) on pregnancy outcomes is relatively sparse. (
  • Outcomes were compared with unexposed women ( n = 3816). (
  • The only observed differences between exposed and unexposed groups was an increased risk of fetal distress in women with lifetime AN and a trend toward increased risk of being hospitalized during pregnancy for women with lifetime AN + BN. (
  • While the Generation R study suggests that having a history of eating disorder does not exert a strong negative effect on pregnancy outcomes, one of its most significant limitations is that it is not clear how many of the women enrolled in this study had active ED symptoms. (
  • Consistent with earlier studies, this finding argues that women with active symptoms of AN may have worse pregnancy outcomes. (
  • It has been our clinical experience that many women with eating disorders are better able to manage their symptoms during pregnancy than at other times. (
  • In this study, our observation is supported by the finding that women with anorexia nervosa, although they tend to have a lower weight at the beginning of pregnancy, gain weight at a more rapid rate than women without ED. Similarly, women with a history of bulimia nervosa had a higher body weight but a lower rate of weight gain. (
  • While this population-based study indicates that most women with a history of eating disorder will do well during pregnancy, it will be important in future studies to examine whether all women with ED gain adequate weight in pregnancy, and, if not, what risk factors predict poor gestational weight gain in this population. (
  • Women enrolled in the second study, designed to evaluate pregnancy and perinatal outcomes in women with PCOS, had 10 additional follow-up antenatal visits. (
  • Within the cohort, 1,715 women (62%) had one or more pregnancies resulting in a live birth after screening. (
  • Based on these findings, it appears that women with PCOS and these features should be the focus of increased surveillance during pregnancy in order to help mitigate these women's and their children's increased risk of disease. (
  • Everyone knows that gaining excess weight during one pregnancy is bad, but clinicians rarely consider weight gains and losses from one pregnancy to the next--especially in normal-weight women. (
  • Second, pregnancy weight counseling and management should be given equally to all women, not just the ones who are very overweight. (
  • The study showed that compared with obese women, normal-weight women gained about 6.6 pounds (3 kg) more during both pregnancies and lost about 4.4 pounds (2 kg more) between births. (
  • The bottom line is that women and their perinatal care providers need to pay attention to appropriate weight before, during, and after each pregnancy to set the stage for optimal outcomes in the next pregnancy,' Weiss said. (
  • Nurse-visited women in the Elmira trial also had diets that improved significantly more over the course of pregnancy than did women in the control group, and had significantly fewer kidney infections than their control group counterparts. (
  • In Memphis, nurse-visited women had significantly fewer diagnoses of pregnancy-induced hypertension, a condition that can compromise the health of the mother and the developing fetus. (
  • In all three trials, nurse-visited women had longer intervals between the births of first and second children, due to better pregnancy planning. (
  • Researchers at Washington University School of Medicine in St. Louis, who conducted the study believe that the discovery suggests that women, who are obese, have type 2 diabetes or a family history of type 2 diabetes, may one day have successful pregnancies. (
  • In multiple pregnancies (twins, triplets and more), the metabolic rate of the mother is greater than in women who are carrying a single baby so that a high-calorie diet may also help maintain the mother's nutritional state. (
  • That is, there is no evidence from randomised trials to advise whether specific dietary advice for women with multiple pregnancies does more good than harm. (
  • There is no robust evidence from randomised trials to indicate whether specialised diets or nutritional advice for women with multiple pregnancies do more good than harm. (
  • Because fetal outcome is best at a particular range of maternal weight gain, it has been suggested that women with multiple pregnancies should take special diets (particularly high-calorie diets) designed to boost weight gain. (
  • It is therefore important to establish if specialised diets are actually of benefit to women with multiple pregnancies and their babies. (
  • To assess the effects of specialised diets or nutritional advice for women with multiple pregnancies (two or more fetuses). (
  • Randomised controlled trials , 'quasi-random' studies, and cluster-randomised trials of women with multiple pregnancies (two or more fetuses) either nulliparous or multiparous and their babies. (
  • Background- Cardiopulmonary exercise testing is often used to evaluate exercise capacity in adults with congenital heart disease including women who are considering pregnancy. (
  • Methods and Results- We conducted a multicenter retrospective observational study of women with congenital heart disease who had undergone cardiopulmonary exercise testing within 2 years of pregnancy or during the first trimester. (
  • We identified 89 pregnancies in 83 women. (
  • Conclusions- Abnormal chronotropic response correlates with adverse pregnancy outcomes in women with congenital heart disease and should be considered in refining risk stratification schemes. (
  • Among women under age 35, over half of pregnancies resulted in birth or ongoing pregnancy, while one third miscarried and 13% were ectopic (suspected or documented). (
  • Among women with average fallopian tube lengths measuring 7.5 cm or longer, 65% of cases gave birth or had an ongoing pregnancy by the end of the study period. (
  • The Pregnancy Outcome Prediction (POP) Study is a prospective cohort study of 4,512 women that have never given birth recruited at the Rosie Hospital (Cambridge, UK) between January 2008 and July 2012. (
  • Nulliparous women with a viable singleton pregnancy were recruited to the POP study when attending their dating ultrasound scan at The Rosie Hospital (Cambridge, UK). (
  • A predominantly white, suburban, indigent population of pregnancy women were followed up to determine the incidence of domestic violence and its effect on preterm delivery, low birth weight, and outcome of pregnancy (infant admission to the neonatal intensive care unit. (
  • The objective of the study was to evaluate the impact of pre-obesity and obesity among pregnant women, describing its prevalence and risk factors, and their association with adverse pregnancy outcomes. (
  • A cohort of 5,564 pregnant women, aged 20 years or more, enrolled at aproximately 20 to 28 weeks of pregnancy, seen in prenatal public clinics of six state capitals in Brazil were followed up, between 1991 and 1995. (
  • Overweight nutritional status (obesity and pre-obesity) was seen in 25% of adult pregnant women and it was associated with increased risk for several adverse pregnancy outcomes, such as gestational diabetes and pre-eclampsia. (
  • AbstractEmerging evidence suggests that bariatric surgery improves pregnancy outcomes of women with obesity by reducing the rates of gestational diabetes, pregnancy-induced hypertension, and macrosomia. (
  • Danish researchers report that women who consume fish or seafood once a week during the first 16 weeks of pregnancy have a 3.6 times lower risk of giving birth to a low birth weight (less than 2500 grams) or premature (born before 259 days) baby than do women who never consume fish or seafood. (
  • 12 Of 112 pregnancies in women with untreated coeliac disease, 20 ended in miscarriages compared with two of 22 in patients on a gluten free diet. (
  • Notwithstanding this scenario and the high incidence of coeliac disease in the general population, there are no data about the prevalence of untreated coeliac disease in women who have experienced an unfavourable outcome of pregnancy. (
  • When we meet women for consultations regarding the use of psychotropic medications during pregnancy, we focus primarily on the impact of medications on the developing fetus and the pregnancy. (
  • In studies of pregnant women with unipolar depression, it has been shown that untreated psychiatric illness in the mother may have a negative impact on pregnancy outcomes, influencing the length of gestation and birthweight. (
  • There is far less data on pregnancy outcomes in women with bipolar disorder. (
  • A recent study reviews and analyzes pregnancy outcomes in women with bipolar disorder. (
  • In this report, researchers reviewed published studies which included women with a diagnosis of bipolar disorder prior to pregnancy who were pregnant and/or followed for one year after childbirth. (
  • The researchers found that adverse pregnancy outcomes, including gestational hypertension, antepartum haemorrhage, and placenta previa, occurred more frequently in women with bipolar disorder. (
  • The clearest finding in this meta-analysis was that women with bipolar disorder were at increased risk for psychiatric illness during pregnancy and the postpartum period. (
  • In this study, Boden and colleagues analyzed pregnancy outcomes in women with bipolar disorder and concluded that bipolar disorder in women, whether treated with medication or not, was associated with worse pregnancy outcomes. (
  • When counseling women with bipolar disorder who are pregnant or planning to conceive, we must focus on optimizing treatment during pregnancy, acknowledging that the avoidance of all medications is not necessarily the safest option. (
  • Women planning a pregnancy must be properly counseled regarding the risks of treatment versus the risks associated with the untreated psychiatric illness in the mother, and the woman's health care provider plays an important role in weighing these individual risks and selecting the best options for treatment. (
  • Risks of adverse pregnancy and birth outcomes in women treated or not treated with mood stabilisers for bipolar disorder: Population based cohort study. (
  • RESULTS Thirty one live births (one twin) resulted from 35 pregnancies in 18 women (seven with cirrhosis). (
  • Amenorrhoea and anovulation are common in women with established cirrhosis, and pregnancy was previously reported to be relatively rare. (
  • The other five patients (2 PM, 3 DM) with the disease in remission had uneventful pregnancies and healthy babies were delivered. (
  • We teach that you can't generalize your findings until you are sure the work is repeatable [but] I think it is important that we make people aware of this problem and how it can impact pregnancy and babies. (
  • Early identification and intervention of high-risk pregnancies increase the chances of delivering full-term, healthy babies. (
  • Using a proactive and robust identification process and an evidenced-based approach to early intervention and case management, together with Optum, OB/GYN providers, and our expectant mothers earlier during pregnancy, we can give babies their best chance for healthy lives," said Dr. Adolfo Valadez, Chief Medical Officer for FirstCare. (
  • Early intervention programs are not simple, but they are instrumental to delivering healthier outcomes for healthier babies. (
  • They looked at outcomes for mothers and babies when midwives were the main providers of care, compared to medical-led or shared care models. (
  • The research concluded that, as babies born to mothers on antidepressants during pregnancy are more likely to be premature, have low birthweight and be admitted to the neonatal unit, identification and treatment during the perinatal period is crucial. (
  • Nurse-Family Partnership's first stated goal is improved pregnancy outcomes: healthier mothers who can deliver healthier babies. (
  • It has been suggested that a special high-calorie diet for the pregnant woman might improve the outcomes for babies. (
  • However, 'optimal weight gain' in the mother in retrospective studies may merely reflect good growth of her babies and delivery at or near term (both associated with a good outcome ) and artificially boosting weight gain by nutritional input may confer no advantage. (
  • If possible, surveillance programmes should aim to ascertain congenital anomalies among all pregnancy outcomes, with the exception of early spontaneous abortions. (
  • A spontaneous abortion is the loss of a fetus during pregnancy due to natural causes. (
  • The term "miscarriage" is the spontaneous termination of a pregnancy before fetal development has reached 20 weeks. (
  • Regarding the four patients (3 PM, 1 DM) with active disease at the time of pregnancy, two pregnancies ended in prematurity, four ended in spontaneous abortion and one healthy baby delivered. (
  • Outcomes included preterm birth, elective and spontaneous loss, and major congenital anomalies. (
  • A significant proportion of spontaneous abortions and unfavourable pregnancy outcomes have no specific cause. (
  • Learn about adverse pregnancy and birth outcomes (e.g., miscarriage, fetal death, preterm birth, and low birthweight), and EHIB's activities to address these issues. (
  • In particular, time to pregnancy seems to affect the risks of Miscarriage , pregnancies in which the embryo implants outside of the womb, and multiple live births. (
  • Pregnancies ending in Miscarriage , both early and late, took longer to achieve than those ending in live births, the authors report. (
  • Pregnancies in homes with measured fields above 0.2 microT or high wire codes were not more likely to end in miscarriage, low birth weight, or preterm delivery. (
  • Concerns during these pregnancies include the risk of fetal malformation, miscarriage, perinatal death, and increased seizure frequency. (
  • The miscarriage rate reported in the general population ranges from approximately 20% to 50% depending on a woman's age and how early pregnancy testing is performed. (
  • Data on the carriers and the results of their prenatal analyses were retrieved as well as data on their previous pregnancies. (
  • Her previous pregnancies were nancy may play a role in the pathogenesis uncomplicated. (
  • What's more important is how a woman has managed her weight gain and loss in previous pregnancies. (
  • Educate her on her specific risks for a poor pregnancy outcome. (
  • Diabetes - but not a diabetes drug - has been linked to poor pregnancy outcomes. (
  • Overall there was little evidence in this general population sample that lifetime ED was associated with increased risk of poor pregnancy outcomes. (
  • This cycle perpetuates with each pregnancy, and it's this rollercoaster weight gain and loss --not just what a woman typically weighs--that predicts poor pregnancy outcomes. (
  • This gain-lose-gain cycle and associated poor pregnancy outcomes reflects Yakusheva's own experience with her two children. (
  • It has previously been reported that high nutrient intakes which promote rapid maternal growth throughout pregnancy are associated with poor pregnancy outcome when compared with normally growing adolescent animals. (
  • The risk for preterm birth, low birth weight, and small size for gestational age increased by 1.9%, 3.3%, and 1.5%, respectively, each month that the time between pregnancies was shortened from 18 months. (
  • After birth, the recommended interval to next pregnancy is at least 18 months and no longer than 60 months in order to reduce the risk of adverse [birth] outcomes," Conde-Agudelo tells WebMD. (
  • In an editorial accompanying the study, Royce writes that interventions to increase the time between pregnancies, such as encouraging breastfeeding and improving access to birth control , could reduce infant deaths. (
  • When considering all pregnancies involving carriers, 52.7% of those to female carriers and 61.8% of those to male carriers led to the birth of a healthy child. (
  • More than half of the pregnancies led to the birth of a healthy child, but prediction of which couples will be successful in obtaining a pregnancy with or without assisted reproductive technologies and/or embryo selection remains difficult. (
  • Primary outcomes were birth weight above the 90th percentile for gestational age, primary cesarean delivery, clinically diagnosed neonatal hypoglycemia, and cord-blood serum C-peptide level above the 90th percentile. (
  • A unique study found that sanitation practices such as open defecation are associated with elevated risk of adverse birth outcomes in rural India. (
  • Associations between maternal glycemia and increased size at birth, delivery by cesarean section, development of neonatal hypoglycemia, and the presence of fetal hyperinsulinemia were the predefined primary outcomes of the study. (
  • Among pregnancies ending in a single live birth, the time to pregnancy was directly linked to the risk of preterm delivery, the report indicates. (
  • Transparency in racial disparities of pregnancy and birth outcomes is an essential step in ensuring better outcomes for all pregnant New Yorkers. (
  • In addition, urine testing found evidence of Ureaplasma species infections, but they did not appear to play a significant role in pregnancy or birth outcomes. (
  • Created by FirstCare Health Plans (FirstCare) in 2008, the Expecting the Best ® maternity program leverages early identification and intervention, ongoing patient education, social support, and proactive prenatal care to improve birth outcomes. (
  • The poor outcomes include major birth defects and pregnancy loss. (
  • The risk of major birth defects was 5.1% (20/392) in pregnancies exposed to metformin during the first trimester and 2.1% (9/431) in the reference group. (
  • We used a fully recursive system of linear and logistic regression equations to examine the relationships among weight changes in the four perinatal periods with maternal (gestational diabetes mellitus, gestational hypertension, cesarean birth) and neonatal (macrosomia, small for gestational age, large for gestational age, low birth weight, congenital anomalies, and perinatal death) adverse outcomes in the second pregnancy. (
  • Data on prescription drug use, pregnancies, deliveries, and the newborn infants' health were obtained from the Swedish Medical Birth Register, the Prescribed Drug Register, and the Swedish Neonatal Quality Register. (
  • Daily use of snus during pregnancy is associated with a modest reduction in average birth weight. (
  • Daily use of snus during pregnancy is not associated with risk of small-for-gestational-age birth. (
  • During the period with circulating influenza virus, maternal immunization during pregnancy was associated with a lower proportion of infants who were small for gestational age and an increase in mean birth weight. (
  • Data derived from the Generation R study , a longitudinal population-based birth cohort study conducted in the Netherlands, suggest that maternal eating disorders may have less of an impact on pregnancy outcomes than earlier reported. (
  • Supplements of vitamin D during pregnancy may increase birth weight and length of newborns, says a new systematic review and meta-analysis of 13 randomized controlled trials. (
  • PURPOSE: In 1992, the International Lamotrigine Pregnancy Registry was initiated to enroll prospectively and to monitor pregnancies exposed to lamotrigine (LTG) for the occurrence of major birth defects. (
  • Pregnancy-outcome ascertainment is obtained through subsequent follow-up with the reporting health care provider, and each reported birth defect is reviewed by an expert pediatrician. (
  • The percentage with major birth defects in pregnancies with known birth defect status was calculated for LTG monotherapy and for polytherapy stratified by trimester of exposure. (
  • RESULTS: The registry identified 334 first-trimester LTG pregnancy outcomes exposed to LTG monotherapy or polytherapy during the first trimester and involving either a live birth with or without a major birth defect or an abortion with a major birth defect. (
  • The researchers, who examined 24,795 linked birth records from 2006 to 2013, say first-pregnancy weight gain and subsequent weight loss after birth starts this unhealthy rollercoaster--which in turn increases the risk for gestational diabetes, hypertension, cesarean delivery and fetal macrosomia (bigger-than-average baby) in the next pregnancy. (
  • The International Collaboration on Air Pollution and Pregnancy Outcomes (ICAPPO) was formed to better understand relationships between air pollution and adverse birth outcomes through standardized parallel analyses in datasets from different countries. (
  • Collaboration participants have datasets with air pollution values and birth outcomes. (
  • Closely spaced pregnancies (within 18 months after the previous live birth) are associated with poor birth outcomes (preterm birth, low birthweight infants and neonatal mortality) and reduced prenatal care 5 . (
  • 5. March of Dimes (2015).Fact Sheet: Birth Spacing and Birth Outcomes. (
  • Status of Birth Outcomes in Clients of the Nurse-Family Partnership. (
  • Multiple pregnancies are associated with higher rates of perinatal mortality and morbidity than singleton pregnancies, mainly due to an increased risk of preterm birth. (
  • The one method, which is in common use in Norway, is to assess birth weight in light of gestational age, where one would say that a child is underweight (small for gestational age) if it is below the 10 percentile weight for his pregnancy week. (
  • The research will study pregnancy and birth outcomes. (
  • The condom is more effective at preventing pregnancy than the birth control pill. (
  • Therefore, we elected to estimate body composition, in particular fat mass and percent body fat, as specific outcomes in the HAPO Study cohort. (
  • Impact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: a population-based cohort study. (
  • Low consumption of seafood in early pregnancy as a risk factor for preterm delivery: prospective cohort study. (
  • AIMS To assess maternal and fetal outcomes in relation to clinical management of pregnancy in a large cohort of patients with well defined AIH. (
  • Mothers who were overweight at the start of pregnancy had the fewest fetal and neonatal deaths with a 16 pound weight gain at term. (
  • This study was conducted to determine the association between prolonged smokeless tobacco (ST) use for more than 5 years by mothers and pregnancy outcome. (
  • With a wealth of data at our fingertips, health insurers are uniquely positioned to identify high-risk pregnancies early on and connect mothers-to-be with necessary education, social support, and clinical care. (
  • We compared infants exposed to ADHD medication during pregnancy with infants whose mothers never used these drugs and infants whose mothers used ADHD medication before or after pregnancy. (
  • Among 964 734 infants, 1591 (0.2%) were exposed to ADHD medication during pregnancy and 9475 (1.0%) had mothers treated before or after pregnancy. (
  • Maternal stress during pregnancy has negative outcomes and children born to such mothers could be victims of obesity and Type 2 diabetes. (
  • 2 In the current article, we report the results of a secondary analysis to assess the hypothesis that influenza immunization influenza the outcomes of infants whose mothers were exposed to influenza during pregnancy. (
  • Scientists from Spain, the USA, and Peru report that newborns of mothers who took vitamin D supplements during pregnancy were 108 grams heavier and 0.3 cm longer than newborns from mothers who did not take the D supplements. (
  • METHODS: LTG pregnancy exposures are voluntarily reported to the registry by health care providers before they are aware of each pregnancy outcome. (
  • Although there are published data on frequency of major malformations after VPA exposures in pregnancy, between-study differences in methods and source populations and the wide confidence intervals around the estimate for LTG and VPA limit the utility of comparison with such data, and no conclusions are made at this time about this combination. (
  • METHODS A review of all known pregnancies in 162 females with definite AIH attending our clinics between 1983 and 1998, with respect to treatment, natural history, and outcome. (
  • Using vital records and crash reports, investigators were able to study the association among car crashes, vehicle safety features and adverse pregnancy outcomes. (
  • This study highlights the importance of crashes during pregnancy and their possible adverse effects on pregnancy outcomes. (
  • The objective of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study was to clarify the risk of adverse outcomes associated with degrees of glucose intolerance in pregnancy less severe than overt diabetes. (
  • The aim of this study was to evaluate the effects of foscarnet on the entire period of rat pregnancy. (
  • This study determined the relationship of maternal weight gain in pregnancy to its outcome. (
  • Trasler JM, Hales BF, Robaire B. A time-course study of chronic paternal cyclophosphamide treatment in rats: effects on pregnancy outcome and the male reproductive and hematologic systems. (
  • Reuters Health) - Maternal tetanus, diphtheria, and acellular pertussis (Tdap) vaccination during pregnancy isn't associated with adverse outcomes for offspring through early childhood, a new study suggests. (
  • We already know that there are very strong benefits of Tdap vaccination during pregnancy, which has been shown to significantly reduce pertussis infections in young infants, who are most vulnerable to this particular infection," said senior study author Deshayne Fell of the school of epidemiology and public health at the University of Ottawa and the Children's Hospital of Eastern Ontario (CHEO) Research Institute. (
  • The study was also underpowered for certain rare adverse outcomes such as neoplasm. (
  • The results validate the use of maternal Tdap vaccination during pregnancy, which is the current standard of care, Dr. Maldonado, who wasn't involved in the study, said by email. (
  • Having results from a study like this should be reassuring for those who are in the process of deciding whether to get vaccinated during pregnancy or not. (
  • OBJECTIVE- To examine associations of neonatal adiposity with maternal glucose levels and cord serum C-peptide in a multicenter multinational study, the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study, thereby assessing the Pederson hypothesis linking maternal glycemia and fetal hyperinsulinemia to neonatal adiposity. (
  • Results of the study showing continuous relationships of maternal glucose levels below those diagnostic of diabetes with each of the primary outcomes have been reported ( 2 ). (
  • The aim of our study was to assess the prevalence and outcome of pregnancy in idiopathic inflammatory myopathy patients who became pregnant after the onset of the disease. (
  • For the purpose of sample size estimation in the overall study, we used a binary outcome and associated measures of sensitivity and likelihood ratio as determinants of the value of these tests. (
  • Liddiard, A., Bhattacharya, S. and Crichton, L. (2011) Elective and Emergency Cervical Cerclage and Immediate Pregnancy Outcomes: A Retrospective Observational Study. (
  • While this new study offers greater insight than existing reports, more population-based studies are necessary to increase understanding of the effect of multiple crashes, seatbelts, and airbags on pregnancy outcomes. (
  • Diana Swift, a reporter for MedPage Today, shares results published in Lupus Science & Magazine from Hospital for Special Surgery's PROMISSE (Predictors of pRegnancy Outcome: bioMarkers In antiphospholipid antibody Syndrome and Systemic lupus Erythematosus) study . (
  • The results of this study provide further evidence that cause and duration of maternal ITP are important determinants of the outcomes of pregnancy. (
  • The relationship of measured residential magnetic fields and wire codes to pregnancy outcome was examined in data collected for a study of childhood cancer in Denver. (
  • Men who were 50 or older had a 28 percent increased risk of that outcome, the study authors said. (
  • Dr. Anthony Vintzileos, chair of obstetrics and gynecology at NYU Winthrop Hospital in Mineola, N.Y., said the study may open the way for more research on how dad's age may play a role in pregnancy and child health. (
  • Results from a new study confirm that ultrasound reliably predicts success and failure of single-dose methotrexate treatment of ectopic pregnancy. (
  • We performed a secondary analysis of data from the Mother's Gift project, a randomized study designed to test the effectiveness of inactivated influenza and pneumococcal vaccines during pregnancy. (
  • The primary outcomes of this study have been reported. (
  • This study presents results as of September 2001 on 168 outcomes exposed to LTG monotherapy and 166 outcomes after pregnancies exposed to LTG polytherapy during the first trimester. (
  • This study evaluated the influence of maternal blood folate, vitamin B(12), homocysteine and 10 folate pathway gene variants on IVF outcome. (
  • This coincides with another recent study showing that elevated markers for stress are associated with decreased pregnancy rates. (
  • And now medical students will be learning about acupuncture at the same time as they study the latest high tech interventions as a new medical textbook, Infertility and Assisted Reproduction (Cambridge University Press), includes a chapter co-authored by Magarelli entitled How Chinese Medicine Impacts Outcomes in Fertility Care. (
  • Thorough design of the POP study and careful sample collection allowed the creation of an extensive, optimally phenotyped biobank of complicated and healthy pregnancies, including approximately 230,000 blood and tissue samples stored in -80°C freezers, 24,000 formalin fixed placental biopsies, and 4,000 paternal DNA samples. (
  • Surveillance programmes aim to ascertain congenital anomalies among all pregnancy outcomes - live births, fetal deaths and terminations of pregnancy - if possible (see Fig. 3.12 ). (
  • Fig. 3.13 indicates that in Wales, Tuscany (in Italy) and the Northern Netherlands, for example, 100% of fetuses with anencephaly are ascertained through pregnancy terminations, while in Utah (in the USA), 50% are ascertained through terminations, 40% through fetal deaths and only 10% as live births. (
  • While the current findings support previous reports, studies that have compared the time to pregnancy with pregnancies ending in live births to the rate of pregnancies outside of the womb and stillbirths have, "to the best of our knowledge, never previously been performed," Dr. Anna Axmon and Dr. Lars Hagmar, from University Hospital in Lund, note. (
  • By contrast, multiple live births were associated with shorter time to pregnancy . (
  • The outcome for emergency cerclage was 3 stillbirths (IUFD) and 7 live births (6 survived with 1 early neonatal death). (
  • Physicians are interested in whether or not certain high-risk pregnancies are associated with future developments of cardiovascular disease. (
  • After an initial assessment, participants identified with high-risk pregnancies were immediately connected with nurse case managers who conducted regular coaching calls and arranged treatments and services - such as access to medication to prevent premature delivery and a 24-hour BabyLine ® staffed with experienced maternity nurses. (
  • These findings are important because they change our views on the perceived safety of e-cigarettes as alternatives to traditional cigarettes before and during pregnancy,' Caron said. (
  • Lead author Dr. Alice Panchaud from the Harvard T.H. Chan School of Public Health, Lausanne University Hospital, and Geneva University said: 'Our findings provide the first reassuring evidence that metformin might offer a cheaper and simpler alternative to insulin for the management of pre-gestational diabetes in pregnancy when effective. (
  • PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest shifting from a traditional model of obstetrical care to a laborist model improves pregnancy outcomes. (
  • Reviews find a likely adverse effect of air pollution on perinatal outcomes, but variation of findings hinders the ability to incorporate the research into policy. (
  • Nutrition and Lifestyle in Pregnancy offers an overview of the latest research findings and international recommendations on a variety of nutrition-related aspects and outcomes of pregnancy. (
  • Including as many types of pregnancy outcomes as possible improves case detection. (
  • Overall, there were no significant associations between Tdap exposure in utero and an increased risk of adverse outcomes in childhood, the researchers report in Pediatrics. (
  • The time needed to achieve pregnancy appears to affect the outcome of that pregnancy , Swedish researchers report. (
  • Further studies are needed to shed light on the mechanisms involved in the association between time to pregnancy and pregnancy outcomes, the researchers conclude. (
  • Miscarriages: About 1 in 5, usually very early in pregnancy. (
  • About 65 percent of those who have had 2 or more miscarriages will have a successful subsequent pregnancy. (
  • With increasing age, the percentage of pregnancies resulting in births declined due to an increasing percentage of miscarriages. (
  • The percentage of births decline as miscarriages and ectopic pregnancies become more common with shorter tubal lengths. (
  • Statistics show that approximately half of pregnancies in the U.S. are unplanned. (
  • Because approximately half of pregnancies in the United States are unplanned, delivering preconception care during general wellness visits could help reduce infant and maternal mortality rates," said Gardiner. (
  • The presence of a village midwife during pregnancy is also associated with increased birthweight. (
  • As a result, L.M. was able to avoid gestational hypertension during her pregnancy and delivered a full-term, healthy baby girl. (
  • Little changes that increase the time between pregnancies could have a huge public health impact," epidemiologist Rachel Royce, PhD, tells WebMD. (
  • The amount of time between pregnancies also has a strong effect on the health of children. (
  • Abstract 79: Does the laborist model improve obstetric outcomes? (
  • Some countries have the ability and resources to ascertain all or most of these outcomes when they occur relatively late in pregnancy, but it is extremely difficult to systematically ascertain those occurring prior to 28 weeks' gestation and, in particular, those in which the pregnancy is terminated. (
  • Aplastic anaemia may develop during was of general weakness, loss of appetite pregnancy and sometimes improve sponta- and easy bruising at 16 weeks gestation. (
  • After exposure to e-cigarette vapor, female mice showed decreased embryo implantation and a significant delay in the onset of pregnancy with the first litter. (
  • One hundred and four female idiopathic inflammatory myopathy patients had 186 pregnancies, but only nine of these patients (4 polymyositis-PM, 5 dermatomyositis-DM) became pregnant after the onset of the disease. (
  • Nine patients with pregnancies after the disease onset had 14 gravidities. (
  • Some adverse outcomes were significantly lower among Tdap-exposed infants than among unexposed infants, the authors note. (
  • Influenza infection in young infants is common and results in high rates of hospital admission, 1 but infection can be prevented by immunization of the mother during pregnancy. (
  • Socioeconomic variation in decisions regarding termination of pregnancy after antenatal detection, however, has resulted in wide socioeconomic inequalities in liveborn infants with a congenital anomaly and subsequent neonatal mortality. (
  • He has developed an interest in the outcome of infants exposed to prenatal drugs, both medicinal and recreational, as part of his work assessing children prior to adoption. (
  • Fig. 3.13 and Fig. 3.14 show how inclusion of the different types of pregnancy outcomes has improved case ascertainment for anencephaly and spina bifida in 14 countries. (
  • Pregnancy losses after the 20th week are categorized as preterm deliveries. (
  • Six pregnancies resulted in normal deliveries, two ended in prematurity, six ended in abortions (two induced abortions). (
  • A total of 152 successful pregnancies and 161 deliveries were included. (
  • Multiple successful pregnancies included 7 twins and 1 triple pregnancy. (
  • Eighty-eight percent of participants initiated prenatal care in their first trimester of pregnancy, exceeding both the national rate of 70.8 percent and the Healthy People 2020 goal of 77.9 percent - resulting in a 38 percent reduction in neonatal intensive care unit (NICU) admissions. (
  • 4. Olds DL, Henderson CR Jr., Tatelbaum R, Chamberlin R. Improving the delivery of prenatal care and outcomes of pregnancy: a randomized trial of nurse home visitation. (
  • One important finding was that maternal delivery outcomes-including eclampsia and hemorrhage for the mother, and preterm delivery-were significantly worse when the cholecystectomy was done during pregnancy as opposed to postpartum, Dr. Pitt said. (
  • And we know that preterm delivery is associated with neonatal mortality and multiple adverse outcomes for the baby," Dr. Pitt said. (
  • Longer fallopian tube segments are associated with better pregnancy outcomes than shorter tubes (Table 9). (
  • It is controversial whether maternal hyperglycemia less severe than that in diabetes mellitus is associated with increased risks of adverse pregnancy outcomes. (
  • Attention to pregnancy weight during and between pregnancies is important for targeted weight counseling to reduce risks in subsequent pregnancies. (
  • Single embryo transfer is an effective way of reducing these risks but it may reduce the chances of pregnancy compared with double embryo transfer. (
  • BACKGROUND There is a paucity of data in the literature on the risks associated with, and optimal management of, pregnancy in patients with autoimmune hepatitis (AIH). (
  • Is the Subject Area "Hypertensive disorders in pregnancy" applicable to this article? (
  • If she desires pregnancy again: discuss timeline, reproductive life plan. (
  • Child Trends included measures from four mediating outcome domains (intentions, knowledge, self-efficacy, and attitudes about sexual activity and contraceptive use) that are linked to reproductive health behaviors. (
  • Is supine exercise associated with adverse maternal and fetal outcomes? (
  • Adverse pregnancy outcomes are of significance because adverse previous pregnancy outcomes are directly related to subsequent pregnancy outcomes. (
  • Participants All registered cases of nine selected congenital anomalies with poor prognostic outcome audited as part of the United Kingdom's fetal anomaly screening programme with an end of pregnancy date between 1 January 1998 and 31 December 2007. (
  • Conclusions Antenatal screening for congenital anomalies has reduced neonatal mortality through termination of pregnancy. (
  • Human studies evaluating the safety of metformin in early pregnancy are scarce, said the paper. (
  • Detailed look at Early pregnancy Symptoms and easy health solutions during 1st, 2nd and 3rd trimester of pregnancy. (
  • Ectopic pregnancy after tubal reversal surgery may be overestimated, since some early pregnancy losses were reported as ectopic pregnancies when serum HCG levels did not rise normally and the pregnancies were interrupted with Methotrexate treatment. (