AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and Occupations
PorphyrinsCoproporphyrinsMetalloporphyrinsHematoporphyrinsPorphyriasUroporphyrinsProtoporphyrinsDeuteroporphyrinsAminolevulinic AcidMesoporphyrinsHarderian GlandHemeFerrochelataseHematoporphyrin DerivativePhotosensitizing AgentsPhotochemotherapyLevulinic AcidsDihematoporphyrin EtherPorphyrinogensPorphobilinogenUroporphyrinogen DecarboxylaseHydroxymethylbilane SynthaseHeminHexachlorobenzene5-Aminolevulinate SynthetaseHemeproteinsSpectrometry, FluorescenceSpectrophotometryPorphyria Cutanea TardaUroporphyrinogensPorphyrias, HepaticProtoporphyrinogen OxidaseDicarbethoxydihydrocollidineMolecular StructureIronPorphobilinogen SynthaseHematoporphyrin PhotoradiationMyoglobinGold CompoundsPhotochemistryCobaltGriseofulvin
Porphyrins
A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
Coproporphyrins
Porphyrins with four methyl and four propionic acid side chains attached to the pyrrole rings. Elevated levels of Coproporphyrin III in the urine and feces are major findings in patients with HEREDITARY COPROPORPHYRIA.
Metalloporphyrins
Porphyrins which are combined with a metal ion. The metal is bound equally to all four nitrogen atoms of the pyrrole rings. They possess characteristic absorption spectra which can be utilized for identification or quantitative estimation of porphyrins and porphyrin-bound compounds.
Hematoporphyrins
Iron-free derivatives of heme with 4 methyl groups, 2 hydroxyethyl groups and 2 propionic acid groups attached to the pyrrole rings. Some of these PHOTOSENSITIZING AGENTS are used in the PHOTOTHERAPY of malignant NEOPLASMS.
Porphyrias
A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
Uroporphyrins
Porphyrins with four acetic acid and four propionic acid side chains attached to the pyrrole rings.
Protoporphyrins
Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes.
Deuteroporphyrins
Porphyrins with four methyl and two propionic acid side chains attached to the pyrrole rings.
Aminolevulinic Acid
A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
Mesoporphyrins
Porphyrins with four methyl, two ethyl, and two propionic acid side chains attached to the pyrrole rings.
Harderian Gland
A sebaceous gland that, in some animals, acts as an accessory to the lacrimal gland. The harderian gland excretes fluid that facilitates movement of the third eyelid.
Heme
The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.
Ferrochelatase
A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA.
Hematoporphyrin Derivative
A complex mixture of monomeric and aggregated porphyrins used in the photodynamic therapy of tumors (HEMATOPORPHYRIN PHOTORADIATION). A purified component of this mixture is known as DIHEMATOPORPHYRIN ETHER.
Photosensitizing Agents
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.
Photochemotherapy
Therapy using oral or topical photosensitizing agents with subsequent exposure to light.
Levulinic Acids
Keto acids that are derivatives of 4-oxopentanoic acids (levulinic acid).
Dihematoporphyrin Ether
The purified component of HEMATOPORPHYRIN DERIVATIVE, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (HEMATOPORPHYRIN PHOTORADIATION); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of PHOTODYNAMIC THERAPY in the United States.
Porphyrinogens
Colorless reduced precursors of porphyrins in which the pyrrole rings are linked by methylene (-CH2-) bridges.
Porphobilinogen
Uroporphyrinogen Decarboxylase
An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.
Hydroxymethylbilane Synthase
An enzyme that catalyzes the tetrapolymerization of the monopyrrole PORPHOBILINOGEN into the hydroxymethylbilane preuroporphyrinogen (UROPORPHYRINOGENS) in several discrete steps. It is the third enzyme in the 8-enzyme biosynthetic pathway of HEME. In humans, deficiency in this enzyme encoded by HMBS (or PBGD) gene results in a form of neurological porphyria (PORPHYRIA, ACUTE INTERMITTENT). This enzyme was formerly listed as EC 4.3.1.8
Hemin
Chloro(7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N(21),N(22),N(23),N(24)) ferrate(2-) dihydrogen.
Hexachlorobenzene
An agricultural fungicide and seed treatment agent.
5-Aminolevulinate Synthetase
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.
Hemeproteins
Proteins that contain an iron-porphyrin, or heme, prosthetic group resembling that of hemoglobin. (From Lehninger, Principles of Biochemistry, 1982, p480)
Spectrometry, Fluorescence
Measurement of the intensity and quality of fluorescence.
Spectrophotometry
The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.
Porphyria Cutanea Tarda
An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form.
Uroporphyrinogens
Porphyrinogens which are intermediates in heme biosynthesis. They have four acetic acid and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl methane in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield uroporphyrins by autooxidation or coproporphyrinogens by decarboxylation.
Porphyrias, Hepatic
A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.
Protoporphyrinogen Oxidase
A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase.
Dicarbethoxydihydrocollidine
1,4-Dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylic acid diethyl ester.
Molecular Structure
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Iron
A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Porphobilinogen Synthase
An enzyme that catalyzes the formation of porphobilinogen from two molecules of 5-aminolevulinic acid. EC 4.2.1.24.
Hematoporphyrin Photoradiation
Photochemotherapy using visible light, usually red, topically or delivered locally by fiberoptic probe to tissues sensitized with hematoporphyrins.
Myoglobin
A conjugated protein which is the oxygen-transporting pigment of muscle. It is made up of one globin polypeptide chain and one heme group.
Gold Compounds
Inorganic compounds that contain gold as an integral part of the molecule.
Photochemistry
Cobalt
A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
Griseofulvin
An antifungal agent used in the treatment of TINEA infections.

Do charge-remote fragmentations occur under matrix-assisted laser desorption ionization post-source decompositions and matrix-assisted laser desorption ionization collisionally activated decompositions? (1/1552)

The precursor ions of tetraphenylporphyrins that are substituted with fatty acids can be introduced into the gas phase by matrix-assisted laser desorption ionization (MALDI) and undergo post-source and collisionally activated decompositions (CAD) in a time-of-flight mass spectrometer. The goal of the research is to obtain a better understanding of post-source decompositions (PSD); specifically, we asked the question of whether ions undergoing PSD have sufficient energy to give charge-remote fragmentations along an alkyl chain. We chose the porphyrin macrocycle because we expected it to act as an inert "support," allowing the molecule to be desorbed by MALDI and to be amenable to charge-remote fragmentation. MALDI-PSD and MALDI-CAD spectra are similar to high-energy CAD spectra and considerably more informative than low-energy CAD spectra, showing that charge-remote fragmentations of the fatty acid moieties do occur upon MALDI-PSD and MALDI-CAD.  (+info)

High efficiency of benzoporphyrin derivative in the photodynamic therapy of pigmented malignant melanoma. (2/1552)

Benzoporphyrin derivative monoacid ring A (verteporfin, BPD-MA) when intravenously injected (5.5 micromol kg(-1)) to C57/BL6 mice bearing a subcutaneously transplanted B1 melanoma gave a maximal accumulation in the tumour within 1-3 h with recoveries of 1.84-1.96 micromol kg(-1). Irradiation of BPD-MA-loaded melanoma with 690-nm light from a dye laser at 3 h and 9 h post injection induced tumour necrosis and delay of tumour growth of 28 and 14 days respectively. The response of the tumour to BPD-MA photosensitization was enhanced by pretreatment with 1064-nm light from a pulse-operated Nd:YAG laser, which caused a selective breakdown of melanosomes.  (+info)

Ultrastructural changes in PAM cells after photodynamic treatment with delta-aminolevulinic acid-induced porphyrins or photosan. (3/1552)

Photodynamic therapy (PDT) is the combination of a photosensitizing drug (Ps) with light in the presence of oxygen leading to the generation of reactive molecular species and destruction of cancer cells. In this study we compared PDT with two Ps, the hematoporphyrin derivative Photosan (Ph) and delta-aminolevulinic acid (ALA)-induced endogenous protoporphyrin IX, with respect to mitochondrial function and ultrastructural alterations. The effects of PDT were investigated in PAM 212 cells after different Ps incubation times, light doses, and post-treatment periods. Both Ps induced a light dose-dependent impairment of the mitochondrial function with the dose-response curve being steep for ALA and flat for Ph. The prolongation of the incubation time from 4 to 20 h resulted in an increased reduction of mitochondrial activity after ALA PDT but not after Ph PDT. Treatment with an irradiation dose that decreased mitochondrial activity by 50% (IC50) led to early and profound changes of mitochondrial morphology in ALA photosensitized cells, whereas photosensitization with Ph resulted in more pronounced alterations of lysosomes. We conclude that at bioequivalent sublethal PDT exposures of PAM 212 cells, ALA-induced damage is primarily restricted to mitochondria, whereas Ph-induced cytotoxicity is mediated by damage of the lysosomal system.  (+info)

Five-coordinate iron-porphyrin as a model for the active site of hemoproteins. Characterization and coordination properties. (4/1552)

Preparation of iron(III)-deuteroporphyrin 6(7)-methyl ester, 7(6)-(histidine methyl ester) by coupling histidine methyl ester to deuterohemin has been performed using the mixed carboxylic/carbonic-acid-anhydride method. This compound, which is very soluble in various organic solvents, can be considered as a prosthetic group model for the active site of five-coordinate hemoproteins. In the oxidized state a basic, a neutral or an acid form can be isolated. The basic and acid forms are monomeric at all concentrations. The neutral form is found dimeric in concentrated solutions while it is monomeric at low concentration. The coordination state of iron in these various species is investigated. The neutral form reacts with ligands, such as nitrogenous organic bases, leading to six-coordinate well-known hemichromes which exhibit low-spin electron spin resonance (ESR) spectra. The reaction of anionic ligands, such as F-, CN-, NO-2 and N-3, with the neutral form model leads to unsymmetrical six-coordinate complexes whose optical and ESR spectra are similar to those of synthetic deuteromyoglobin. In benzene, toluene or dichloromethane solutions iron (II)-deuteroporphyrin 6(7)-methyl ester, 7(6)-histidine methyl ester), obtained from ferric forms by heterogeneous reduction with aqueous dithionite, exhibits an optical spectrum characteristic of a five-coordinate high-spin ferrous complex. At low temperature important spectral modifications are observed indicating a dimeric association. At room temperature it binds one nitrogenous base molecule leading to the well-known hemochrome. It reacts also with carbon monoxide with a very high affinity constant (4.5 X 10(8) M-1), comparable to that of the isolated human hemoglobin alpha and beta chains, but much higher than the values reported for other various models, suggesting that the side-chain length bearing the fifth ligand may have an important influence upon the reactivity of the sixth position of the iron ion. At low temperature in toluene or dichloromethane, this compound reversibly binds oxygen without oxidation of the iron ion while oxidation occurs at room temperature. The significance of these results is discussed in relation with the local environment, the electronic nature of the base and the immobilization of the heme group in hemoproteins.  (+info)

Reaction of the microsomal heme oxygenase with cobaltic protoporphyrin IX, and extremely poor substrate. (5/1552)

A reconstituted heme oxygenase system which was composed of a purified heme oxygenase from pig spleen microsomes and a partially purified NADPH-cytochrome c reductase from pig liver microsomes could not catalyze the conversion of cobaltic protoporphyrin IX (Co-heme) to biliverdin, although Co-heme could bind with the heme oxygenase protein to form a complex. The heme oxygenase system in the microsomes from pig spleen, rat spleen, and rat kidney also failed to oxidize Co-heme to biliverdin. Properties of the complex of Co-heme and heme oxygenase closely resembled those of cobalt myoglobin and cobalt hemoglobin; the Co-heme bound to the heme oxygenase protein did not react with cyanide and azide, the Co-heme moiety was reduced but only slowly with sodium dithionite, and the reduced form of the Co-heme did not appear to bind carbon monoxide. The co-heme bound to heme oxygenase was not reduced with the NADPH-cytochrome c reductase system in air. These findings further support the views that heme oxygenase may have a heme-binding crevice similar to those of myoglobin and hemoglobin and that reduction of heme is the prerequisite for the oxidative degradation of heme in the heme oxygenase reaction.  (+info)

Optimum porphyrin accumulation in epithelial skin tumours and psoriatic lesions after topical application of delta-aminolaevulinic acid. (6/1552)

Photodynamic therapy with topically applied delta-aminolaevulinic acid is used to treat skin tumours by employing endogenously formed porphyrins as photosensitizers. This study examines the time course of porphyrin metabolite formation after topical application of delta-aminolaevulinic acid. Porphyrin biosynthesis in human skin tumours (basal cell carcinoma, squamous cell carcinoma), in psoriatic lesions, and in normal skin was investigated. Skin areas were treated with delta-aminolaevulinic acid, and levels of total porphyrins, porphyrin metabolites and proteins were measured in samples excised after 1, 2, 4, 6, 9, 12 and 24 h. There was an increase in porphyrin biosynthesis in all tissues with maximum porphyrin levels in tumours between 2 and 6 h and in psoriatic lesions 6 h after treatment. The pattern of porphyrins showed no significant difference between normal and neoplastic skin, protoporphyrin being the predominant metabolite. The results suggest that optimum irradiation time for superficial epithelial skin tumours may be as soon as 2 h after application of delta-aminolaevulinic acid, whereas for treatment of psoriatic lesions an application time of 6 h is more suitable.  (+info)

Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb. (7/1552)

We have investigated the expression of heme oxygenase (HO) in the rat kidney and the effects of HO-dependent heme metabolites on the apical 70-pS K+ channel in the thick ascending limb (TAL). Reverse transcriptase-PCR (RT-PCR) and Western blot analyses indicate expression of the constitutive HO form, HO-2, in the rat cortex and outer medulla. Patch-clamping showed that application of 10 microM chromium mesoporphyrin (CrMP), an inhibitor of HO, reversibly reduced the activity of the apical 70-pS K+ channel, defined by NPo, to 26% of the control value. In contrast, addition of 10 microM magnesium protoporphyrin had no significant effect on channel activity. HO involvement in regulation of the apical 70-pS K+ channel of the TAL, was further indicated by the addition of 10 microM heme-L-lysinate, which significantly stimulated the channel activity in cell-attached patches by 98%. The stimulatory effect of heme on channel activity was also observed in inside-out patches in the presence of 0.5-1 mM reduced nicotinamide adenine dinucleotide phosphate. This was completely abolished by 10 microM CrMP, suggesting that a HO-dependent metabolite of heme mediated the effect. This was further supported by exposure of the cytosolic membrane of inside-out patches to a carbon monoxide-bubbled bath solution, which increased channel activity. Moreover, carbon monoxide completely abolished the effect of 10 microM CrMP on the channel activity. In contrast, 10 microM biliverdin, another HO-dependent metabolite of heme, had no effect. We conclude that carbon monoxide produced from heme via an HO-dependent metabolic pathway stimulates the apical 70-pS K+ channel in the rat TAL.  (+info)

A corrinoid-dependent catabolic pathway for growth of a Methylobacterium strain with chloromethane. (8/1552)

Methylobacterium sp. strain CM4, an aerobic methylotrophic alpha-proteobacterium, is able to grow with chloromethane as a carbon and energy source. Mutants of this strain that still grew with methanol, methylamine, or formate, but were unable to grow with chloromethane, were previously obtained by miniTn5 mutagenesis. The transposon insertion sites in six of these mutants mapped to two distinct DNA fragments. The sequences of these fragments, which extended over more than 17 kb, were determined. Sequence analysis, mutant properties, and measurements of enzyme activity in cell-free extracts allowed the definition of a multistep pathway for the conversion of chloromethane to formate. The methyl group of chloromethane is first transferred by the protein CmuA (cmu: chloromethane utilization) to a corrinoid protein, from where it is transferred to H4folate by CmuB. Both CmuA and CmuB display sequence similarity to methyltransferases of methanogenic archaea. In its C-terminal part, CmuA is also very similar to corrinoid-binding proteins, indicating that it is a bifunctional protein consisting of two domains that are expressed as separate polypeptides in methyl transfer systems of methanogens. The methyl group derived from chloromethane is then processed by means of pterine-linked intermediates to formate by a pathway that appears to be distinct from those already described in Methylobacterium. Remarkable features of this pathway for the catabolism of chloromethane thus include the involvement of a corrinoid-dependent methyltransferase system for dehalogenation in an aerobe and a set of enzymes specifically involved in funneling the C1 moiety derived from chloromethane into central metabolism.  (+info)

The effect of β-saturated pyrrolic rings on the electronic structures and aromaticity of magnesium porphyrin derivatives: A...
TY - JOUR. T1 - The effect of β-saturated pyrrolic rings on the electronic structures and aromaticity of magnesium porphyrin derivatives. T2 - A density functional study. AU - Wan, Liang. AU - Qi, Dongdong. AU - Zhang, Yuexing. PY - 2011/1/1. Y1 - 2011/1/1. N2 - Density functional theory (DFT) calculation on the molecular structures, molecular orbitals, electronic absorption spectra, and magnetic properties of magnesium porphyrin (MgPor) and a series of five hydrogenated magnesium porphyrin complexes with different number of β-saturated pyrrolic rings, namely MgPor-β-1Hy, MgPor-β-opp-2Hy, MgPor-β-adj-2Hy, MgPor-β-3Hy, and MgPor-β-4Hy, clarifies the redshift of the lowest energy absorption band from chlorophyll a to bacteriochlorophyll and reveals the strong chemical stability for both of them. The energy levels of highest occupied molecular orbitals (HOMO) and HOMO-1 for MgPor are reversed upon hydrogenation at β-positions (2 and 3, 7 and 8, 12 and 13, and 17 and 18) of porphyrin ring. ...
https://research.kaust.edu.sa/en/publications/the-effect-of-%CE%B2-saturated-pyrrolic-rings-on-the-electronic-struct
Synthesis and Spectroscopy Characteristics of 5-fluorouracil Porphyrin Compounds
Abstract: 5fluorouracil porphyrin compounds are a new type of potential antitumor drugs. Six new 5fluorouracil porphyrin compounds were synthesized first and characterized by means of elemental analysis, IR, 1HNMR and MS. The six 5fluorouracil porphyrin compounds were studied by absorption spectra, steadystate fluorescence spectroscopy and timeresolved single photon measurement, comparing with their primary porphyrin compounds. The 5fluorouracil porphyrin compounds with plentiful excited states and fluorescence lifetime of 7 ns are little influenced by substituents and solvents, which may be advantageously used to make singlet oxygen radical. Key words: 5-fluorouracil, Porphyrin, Fluorescence lifetime, Single photon measurement ...
http://www.whxb.pku.edu.cn/EN/Y2001/V17/I10/879
Biological targeting compositions and methods of using the same - Patent applicationBiological targeting compositions and methods of using the same - Patent application
0151]Examples of metalloporphyrins include cobalt meso-tetra-(4-N-methylpyridyl)-porphine; cobalt (II) meso(4-sulfonatophenyl)-porphine; copper hematoporphyrin; copper meso-tetra-(4-N-methylpyridyl)-porphine; copper (II) meso(4-sulfonatophenyl)-porphine; Europium (III) dimethyltexaphyrin dihydroxide; gallium tetraphenylporphyrin; iron meso-tetra(4-N-methylpyridyl)-porphine; lutetium (III) tetra(N-methyl-3-pyridyl)-porphyrin chloride; magnesium (II) meso-diphenyl tetrabenzoporphyrin; magnesium tetrabenzoporphyrin; magnesium tetraphenylporphyrin; magnesium (II) meso(4-sulfonatophenyl)-porphine; magnesium (II) texaphyrin hydroxide metalloporphyrin; magnesium meso-tetra-(4-N-methylpyridyl)-porphine; manganese meso-tetra-(4-N-methyl-pyridyl)-porphine; nickel meso-tetra(4-N-methylpyridyl)-porphine; nickel (II) meso-tetra(4-sulfonatophenyl)-porphine; palladium (II) meso-tetra-(4-N-methylpyridyl)-porphine; palladium meso-tetra-(4-N-methylpyridyl)-porphine; palladium tetraphenylporphyrin; palladium (II) ...
http://www.patentsencyclopedia.com/app/20100041133
Novel Photocatalytic Function of Porphyrin-Modified Gold Nanoclusters in Comparison with the Reference Porphyrin Compound<...
TY - JOUR. T1 - Novel Photocatalytic Function of Porphyrin-Modified Gold Nanoclusters in Comparison with the Reference Porphyrin Compound. AU - Fukuzumi, Shunichi. AU - Endo, Yoshiyuki. AU - Kashiwagi, Yukiyasu. AU - Araki, Yasuyuki. AU - Ito, Osamu. AU - Imahori, Hiroshi. PY - 2003/10/30. Y1 - 2003/10/30. N2 - The photocatalytic function of three-dimensional porphyrin monolayer-protected gold clusters (MFCs) with different chain lengths has been examined in photocatalytic reduction of hexyl viologen (HV2+) by 1-benzyl-1,4-dihydronicotinamide (BNAH) in comparison with that of the reference porphyrin compound without metal clusters. Both porphyrin monolayer-protected gold clusters and the reference porphyrin compound act as efficient photocatalysts for the uphill reduction of HV2+ by BNAH to produce 1-benzylnicotinamidinium ion (BNA+) and hexyl viologen radical cation (HV•+) in benzonitrile. In the case of porphyrin monolayer-protected gold clusters the quantum yield reaches a maximum value ...
https://tohoku.pure.elsevier.com/en/publications/novel-photocatalytic-function-of-porphyrin-modified-gold-nanoclus
The synthesis of meso-substituted porphyrins: reaction conditions and substituent effectsThe synthesis of meso-substituted porphyrins: reaction conditions and substituent effects
The purpose of this study is to gain a better understanding of the parameters governing the synthesis of meso-substituted porphyrins. As a result of doing so, we anticipate that better reaction conditions can be developed, which will afford porphyrins in higher yields. Porphyrins are a large class of deeply colored red or purple, fluorescent crystalline pigments, of natural or synthetic origin, having in common a substituted aromatic macrocyclic ring consisting of four pyrrole-type residues, linked together by four methine bridging groups. The structure of porphyrin has been known since the early 1900s, but discrepancies exist on how the formation of porphyrin actually occurs. Several methods have been developed for the porphyrin reaction under various conditions. Three of the most common methods for the synthesis of meso-substituted porphyrins are: the Rothemund Method, the Adler Method, and the Lindsey Method. The conditions for these reactions vary from the harsh conditions where the ...
https://athenaeum.libs.uga.edu/handle/10724/20295
PORPHYRIN CHEMISTRY PERTAINING TO THE DESIGN OF ANTICANCER DRUGS .2. THE SYNTHESIS AND IN-VITRO TESTS OF WATER-SOLUBLE...PORPHYRIN CHEMISTRY PERTAINING TO THE DESIGN OF ANTICANCER DRUGS .2. THE SYNTHESIS AND IN-VITRO TESTS OF WATER-SOLUBLE...
Water-soluble, meso-substituted porphyrins are synthesized by sulfonation or methylation of the phenyl or pyridyl groups, respectively, of some non-water-soluble functionalized porphyrins that we have recently synthesized (Can. J. Chem. 72, 1894 (1994)). Twelve anionic sulfonated and seven cationic methylpyridinium porphyrins, usually containing other functional groups (phenyl, pyridyl, nitro- and amino-phenyl), are reported on. Twelve of these porphyrins are new, and all nineteen porphyrins are characterized by H-1 NMR. UV-VIS data are presented for the isolated porphyrins, while mass spectral data are noted for selected compounds. Partition coefficients of the porphyrins in octanol-water, and the accumulation of the porphyrins in HT-29 cells of a human-cancer tumor, were measured and both were inversely related to the charges of the porphyrins. The 11 porphyrins soluble in biological buffer solutions are basically nontoxic to Chinese hamster ovary (CHO) cells in oxic or hypoxic conditions or ...
http://www.chem.ubc.ca/porphyrin-chemistry-pertaining-design-anticancer-drugs-2-synthesis-and-vitro-tests-water-soluble
Early-stage HIV infection and hepatitis C virus infection are associated with elevated serum porphyrin levels<...Early-stage HIV infection and hepatitis C virus infection are associated with elevated serum porphyrin levels<...
TY - JOUR. T1 - Early-stage HIV infection and hepatitis C virus infection are associated with elevated serum porphyrin levels. AU - Lim, H. W.. AU - Pereira, A.. AU - Sassa, S.. AU - Kim, Mimi. AU - Zolla-Pazner, S.. PY - 1998. Y1 - 1998. N2 - Background: Porphyria cutanea tarda is known to be associated with HIV infection and hepatitis C virus (HCV). Objective: Our purpose was to evaluate whether early infection with HIV, with or without HCV infection, is associated with elevated serum porphyrin levels. Methods: Serum porphyrin levels were measured in samples obtained from 103 patients with early HIV infection. The results were compared with those of 89 late-stage HIV-positive patients and 78 HIV-negative patients. Results: The highest median porphyrin level was in early-stage HIV-positive/HCV-positive samples, followed in decreasing order by those in early-stage HIV-positive/HCV-negative, late- stage HIV-positive/HCV-positive, late-stage HIV-positive/HCV-negative, HIV- negative/HCV-positive, ...
https://einstein.pure.elsevier.com/en/publications/early-stage-hiv-infection-and-hepatitis-c-virus-infection-are-ass-2
porphyrin/porphine/917-23-7/porphyrin catalyst/卟啉/卟啉卟啉/化学试剂/当当/卟啉/化学当当
Porphyrin-cn web supplied various porphyrin卟啉催化剂, containing fluorescence porphyrin porphine 917-23-7 & Fe porphyrin Mn porphyrin Cu porphyrin Co porphyrin Ni porphyrin Zn porphyrin & metalloporphyrin
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porphyrin/porphine/917-23-7/porphyrin catalyst/卟啉/卟啉卟啉/化学试剂/当当/卟啉/化学当当
Porphyrin-cn web supplied various porphyrin卟啉催化剂, containing fluorescence porphyrin porphine 917-23-7 & Fe porphyrin Mn porphyrin Cu porphyrin Co porphyrin Ni porphyrin Zn porphyrin & metalloporphyrin
http://porphyrin-cn.com/h-pl.html?m13pageno=2
Self-Assembly of TPPS4 Porphyrin Molecules into Nanorods Investigated by TEM, AFM, STM and UV/VIS Spectroscopy
In this work the aggregates of the tetrakis(4-sulfonatophenyl)porphyrin (TPPS4) growth from solution on solid crystalline hydrophilic and hydrophobic substrates were investigated. The spatial structure of TPPS4 deposited on the surface was imaged using Transmission Electron Microscopy (TEM), Scanning Atomic Force Microscopy (AFM). Scanning Tunnelling Microscopy (STM) visualized porphyrin rings structure with molecular resolution. The aggregation of TPPS4 was investigated by UV_VIS spectroscopy. The TEM investigation revealed a 3-dimensional rod and wheel like molecular order of the TPPS4 porphyrin assemblies, while a corresponding shorter and monodisperse oligomer exhibited 2D ribbon-like structure. The TPPS4 porphyrin molecules self-assemble into micrometer-long nanorods and fibers on substrate surface. Their cross section was determined quantitatively by scanning force microscopy. This revealed a typical thickness of two or four molecular layers and a width of tenths of molecule diameter. This
http://www.nsti.org/procs/Nanotech2005v1/12/W75.05
Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels - SophionPorphyrin derivatives as potent and selective blockers of neuronal Kv1 channels - Sophion
Selective inhibitors of voltage-activated K+ channels are needed for the treatment of multiple sclerosis. In this work it was discovered that porphyrins bearing 2-4 carbon alkyl ammonium side chains predominantly blocked the Kv1.1 current whilst Kv1.2 was susceptible to a porphyrin bearing polyamine side chains.. ...
http://sophion.com/publications/porphyrin-derivatives-potent-selective-blockers-neuronal-kv1-channels/
Synthesis of stannyl porphyrins and porphyrin dimers via Stille coupling and their 119Sn NMR and fluorescence properties | IRIS...Synthesis of stannyl porphyrins and porphyrin dimers via Stille coupling and their 119Sn NMR and fluorescence properties | IRIS...
Free base stannyl porphyrins and free base porphyrin dimers have been successfully synthesized via copper-free Stille coupling in 21−67% yields. This approach provides an access to stannyl porphyrin synthons that were previously unavailable. Moreover, variation of the reaction conditions selectively provides access to either stannyl porphyrins or porphyrin dimers. Full 119/117Sn NMR analysis was used for characterization of the stannyl porphyrins and detailed 119Sn-1H-13C NMR analyses were carried out on a series of the starting tin reagents and the stannyl porphyrins. These investigations indicate that significant structural information can be gathered by use of commonly known NMR techniques. Photophysical properties of the novel porphyrins prepared including absorption, emission, and fluorescence lifetimes were investigated. The stannyl porphyrins emitted in the visible region, and in all cases large Stokes shifts were observed. The emission intensities of the stannyl porphyrins were ...
https://iris.unime.it/handle/11570/1894671
EP 0785941 B1 20000419 - PORPHYRIN LABELING OF POLYNUCLEOTIDESEP 0785941 B1 20000419 - PORPHYRIN LABELING OF POLYNUCLEOTIDES
299057642 - EP 0785941 B1 2000-04-19 - PORPHYRIN LABELING OF POLYNUCLEOTIDES - [origin: WO9611937A1] The invention provides various porphyrin labeled compounds and reagents for labeling molecules with porphyrins. The porphyrin labeled compounds include porphyrin labeled nucleosides, nucleotides, polynucleotides and the like. The porphyrin labeled compounds of the invention are designed so that the porphyrin moiety on the labeled compound may be detected on the basis of a reaction product produced by the porphyrin catalyzed oxidation of a porphyrin detection reagent. The oxidation of the porphyrin detection reagent may result in the formation of light, i.e., a chemiluminescent reaction, or a colored compound, i.e., a colorimetric reaction. The compounds of the invention contain the general structure of: porphyrin-linker-base-sugar-(phos)n-OH. Another aspect of the invention is to provide methods of labeling and detecting polynucleotides by incorporating a porphyrin-labeled nucleotide into a
https://data.epo.org/gpi/EP0785941B1-PORPHYRIN-LABELING-OF-POLYNUCLEOTIDES
Design of Spatial Disposition of Anionic Porphyrins in Matrices of Ammonium Bilayer Membranes<...
TY - JOUR. T1 - Design of Spatial Disposition of Anionic Porphyrins in Matrices of Ammonium Bilayer Membranes. AU - Ishikawa, Yuichi. AU - Kunitake, Toyoki. PY - 1991/1/1. Y1 - 1991/1/1. N2 - A methodology to place charged porphyrin derivatives in specific spatial arrangements in matrices of ammonium bilayer membranes was explored. Aqueous mixtures of anionic copper(II) porphyrins and bilayer dispersions of single-chain and double-chain ammonium amphiphiles were cast on Teflon sheets to produce regular multilayer films. The orientation of doped copper(II) porphyrins was determined by anisotropies of ESR spectral patterns that were dependent on the disposition of the cast film in the magnetic field. Quantitative estimates of the porphyrin orientation were made possible by elaborate computer simulation of the observed spectra. The mode of porphyrin orientation is determined by the distribution of anionic substituents on guest porphyrins and the supramolecular structure of host bilayers. Type III ...
https://kyushu-u.pure.elsevier.com/en/publications/design-of-spatial-disposition-of-anionic-porphyrins-in-matrices-o
DSpace at IIT Bombay: Lipid peroxidation induced by meso-tetrakis[3,4-bis(carboxymethyleneoxy)phenyl]prophyrin on...
The ability of a novel porphyrin, meso-tetrakis[3,4-bis(carboxymethyleneoxy)phenyl]porphyrin (T3,4-CPP), to induce photodamage in subcellular membranes, in the form of rat hepatic and tumor microsomes, was evaluated with a view to locating suitable porphyrin derivative for possible use in photodynamic therapy. This water-soluble porphyrin, on exposure to visible light, induced a significant extent of membrane lipid peroxidation as assessed by the formation of thiobarbituric acid reactive substances, lipid hydroperoxides and conjugated dienes. The peroxidation induced in hepatic microsomes is both time-and concentration-dependent. Using inhibitors of reactive oxygen species and comparing products of peroxidation, it is shown that the damage induced is mainly due to singlet oxygen and partly due to other species like free radicals. T3,4-CPP also caused the generation of singlet oxygen as a function of illumination time. Since membrane damage induced by a sensitizer on photoexcitation has been ...
http://dspace.library.iitb.ac.in/jspui/handle/10054/5939
Aggregation studies of benzoporphyrin derivative | UBC ChemistryAggregation studies of benzoporphyrin derivative | UBC Chemistry
The photophysical properties of a ring B benzoporphyrin derivative 1,3-diene dimethylester were investigated in solution (water-DMSO mixtures). At low proportions of water in DMSO, the diester obeys Beers law at all pH values and ionic strengths investigated. For solvent systems containing more than 30% water, the extent of deviation from Beers law as a function of porphyrin concentration is attributed to formation of porphyrin dimers. Dimerization equilibrium constants (Kd) have been determined in different percentage of solvent mixtures, using absorption and fluorescence spectroscopies, and were found to exhibit a linear correlation between log (Kd) and the inverse of the dielectric constant (log (Kd) = 24.6 - 1060.4 x 1/epsilon (mix)). This equation permits the calculation of Kd in mixtures of water-DMSO.. ...
https://www.chem.ubc.ca/aggregation-studies-benzoporphyrin-derivative
Patent US5268371 - Derivatives of porphyrin and metalloporphyrins optionally coupled to a ... - Google PatentenPatent US5268371 - Derivatives of porphyrin and metalloporphyrins optionally coupled to a ... - Google Patenten
The present invention relates to metallized porphyrin derivatives having the formula: ##STR1## wherein the R and M variables are as defined in the specification. Said porphyrin derivatives having uses as antitumor agents, diagnostics agents, or in therapy.
http://www.google.nl/patents/US5268371
Singlet and triplet excited states of emissive, conjugated bis(porphyrin) compounds probed by optical and EPR spectroscopic...
TY - JOUR. T1 - Singlet and triplet excited states of emissive, conjugated bis(porphyrin) compounds probed by optical and EPR spectroscopic methods. AU - Shediac, Renée. AU - Gray, Mike H.B.. AU - Tetsuo Uyeda, H.. AU - Johnson, Robert C.. AU - Hupp, Joseph T.. AU - Angiolillo, Paul J.. AU - Therien, Michael J.. PY - 2000/7/26. Y1 - 2000/7/26. N2 - The nature of the singlet and triplet excited states of a series of meso-to-meso ethyne-linked bis(porphyrin) compounds was probed by electronic absorption, polarized pump - probe fluorescence, electron paramagnetic resonance (EPR), electroabsorption (Stark), and transient triplet - triplet absorption spectroscopic methods, Pump - probe fluorescence anisotropy experiments show that the presence of meso-ethynyl substituents drives a reorientation of orthogonal x- and y-polarized singlet excited states in the macrocycle frame of reference with respect to that evinced for conventional free-base porphyrin chromophores. Analogous experiments in conjugated ...
https://sofi-northwestern.pure.elsevier.com/en/publications/singlet-and-triplet-excited-states-of-emissive-conjugated-bisporp
The role of enzyme mimetic Mn(III) porphyrins in the redox reactions of biologically active simple inorganic compoundsThe role of enzyme mimetic Mn(III) porphyrins in the redox reactions of biologically active simple inorganic compounds
The activation parameters and the rate constants of the water exchange reactions of MnTE-2-PyP5+ (Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin) as cationic, MnTnHex-2-PyP5+ (Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)-porphyrin) and MnTTEG-2-PyP5+ (Mn(III) meso-tetrakis(N-tri(ethyleneglycol)-pyridinium-2-yl)porphyrin) as sterically shielded cationic, and MnTSPP3- (meso-tetrakis(4-sulfonatophenyl)porphyrin) as anionic Mn(III) porphyrins have been determined from the temperature dependence of 17O NMR relaxation rates. On the basis of the determined entropies of activation, an interchange-dissociative mechanism (Id) was proposed for the cationic complexes (ΔS‡ = ca. 0 J K-1 mol-1) whereas a limiting dissociative mechanism (D) was proposed for MnTSPP3- complex (ΔS‡ = +79 J K-1 mol-1). We found that the in vitro autoxidation of N-hydroxyurea (HU) is catalyzed by MnTTEG-2-PyP5+, which is also a potent mimic of the enzyme superoxide dismutase. The detailed mechanism of the reaction ...
https://dea.lib.unideb.hu/dea/handle/2437/173261
Effect of meso substituents on exchange-coupling interactions in μ-oxo iron(III) porphyrin dimers<...
TY - JOUR. T1 - Effect of meso substituents on exchange-coupling interactions in μ-oxo iron(III) porphyrin dimers. AU - Helms, Jeffrey H.. AU - Ter Haar, Leonard W.. AU - Hatfield, William E.. AU - Harris, David L.. AU - Jayaraj, K.. AU - Toney, Glen E.. AU - Gold, Avram. AU - Mewborn, Tabitha D.. AU - Pemberton, Jeanne E. PY - 1986. Y1 - 1986. N2 - The μ-oxo iron(III) porphyrin dimers [(TPP)Fe]2O, [(TPP(4-OCH3))Fe]2O, [(TPP(4-CF3))Fe]2O, and [(TPP(F5))Fe]2O (where TPP is meso-tetraphenylporphyrin, TPP(4-OCH3) is meso-tetrakis(4-methoxyphenyl)porphyrin, TPP(4-CF3) is meso-tetrakis(4-(trifluoromethyl)phenyl)porphyrin, and TPP(F5) is meso-tetrakis(pentafluorophenyl)porphyrin) have been studied to determine the effect of peripheral substituents on the porphyrin rings on properties of the molecules. Variable-temperature magnetic susceptibility studies on solid samples yielded the following exchange-coupling constants for the antiferromagnetically coupled iron(III) ions: -146.8 cm-1, ...
https://arizona.pure.elsevier.com/en/publications/effect-of-meso-substituents-on-exchange-coupling-interactions-in-
Characterization of Porphyrin Thiol Assemblies on Au (111)Characterization of Porphyrin Thiol Assemblies on Au (111)
Numerous studies have been conducted using porphyrin molecules on various substrates to investigate their diverse photoelectrochemical, catalytic, electronic, and biochemical properties. These properties make porphyrin molecules targets for use as active components in devices such as chemical sensors, information storage, and photo sensitizers in solar cells. In this study, we investigated the assembly and aggregation of mono-podal zinc (II) porphyrin molecules into a dodecanethiol self-assembled monolayer (SAM) on gold. The porphyrin macrocycle is attached to a phenyl linking group and an alkanethiol tether which binds to the gold surface. The charge transport properties of the porphyrin in confined geometries are being investigated based on previous studies of aggregated assemblies on gold surfaces. In these studies, we find small islands of porphyrins to produce unique electrical switching behavior not observed in single molecules. To explore how island size influences the electrical ...
http://oaktrust.library.tamu.edu/handle/1969.1/98372
An Escherichia coli expression-based approach for porphyrin substitution in heme proteinsAn Escherichia coli expression-based approach for porphyrin substitution in heme proteins
The ability to replace the native heme cofactor of proteins with an unnatural porphyrin of interest affords new opportunities to study heme protein chemistry and engineer heme proteins for new functions. Previous methods for porphyrin substitution rely on removal of the native heme followed by porphyrin reconstitution. However, conditions required to remove the native heme often lead to denaturation, limiting success at heme replacement. An expression-based strategy for porphyrin substitution was developed to circumvent the heme removal and reconstitution steps, whereby unnatural porphyrin incorporation occurs under biological conditions. The approach uses the RP523 strain of Escherichia coli, which has a deletion of a key gene involved in heme biosynthesis and is permeable to porphyrins. The expression-based strategy for porphyrin substitution detailed here is a robust platform to generate heme proteins containing unnatural porphyrins for diverse applications ...
https://vivo.scripps.edu/display/e9n299254
DSpace at IIT Bombay: Singlet molecular-oxygen quantum yield measurements of some porphyrins and metalloporphyrins
Hematoporphyrin IX dimethyl ester (HPDME), tetraphenylporphyrin (TPP), tetra(4-methoxyphenyl)porphyrin (TMPP), tetra(3,4-dimethoxyphenyl)porphyrin (TDMPP), tetra(3,4,5-trimethoxyphenyl)porphyrin (TTMPP), tetraanthrylporphyrin (TAP) and tetraacridylporphyrin (TACP), and their Zn2+, SnX2(2+), Pd2+ and Pt2+ complexes have been prepared and characterized. The singlet molecular oxygen quantum yield (phi(DELTA)) values of the above porphyrins and their metal derivatives in N,N-dimethyl formamide (DMF) have been measured in the presence of 1, 3-diphenylisobenzofuran (DPBF) as O-1(2) acceptor using steady state technique after correcting for the intensity of light absorbed by the photosensitizers. The phi(DELTA) values for the free base porphyrins are usually around 0.60. Hematoporphyrin IX dimethyl ester and its metal derivatives follow the order: HPDME (phi(DELTA) = 0.60) , Zn HPDME (0.40) , PdHPDME (0.34) , Sn(OH)2HPDME (0.28) greater-than-or-equal-to PtHPDME (0.24). Zinc(II) complexes of ...
http://dspace.library.iitb.ac.in/jspui/handle/100/1395
The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful...The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful...
The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic.
https://scholars.duke.edu/display/pub748865
Chiroptical properties of anionic and cationic porphyrins and metalloporphyrins in complex with left-handed Z-DNA and right...Chiroptical properties of anionic and cationic porphyrins and metalloporphyrins in complex with left-handed Z-DNA and right...
Fingerprint Dive into the research topics of Chiroptical properties of anionic and cationic porphyrins and metalloporphyrins in complex with left-handed Z-DNA and right-handed B-DNA. Together they form a unique fingerprint. ...
https://yonsei.pure.elsevier.com/en/publications/chiroptical-properties-of-anionic-and-cationic-porphyrins-and-met/fingerprints/
Impact of Substituents and Nonplanarity on Nickel and Copper Porphyrin Electrochemistry: First Observation of a Cu-II/Cu-III...Impact of Substituents and Nonplanarity on Nickel and Copper Porphyrin Electrochemistry: First Observation of a Cu-II/Cu-III...
ABSTRACT Electrochemical studies of the oxidation of dodecasubstitued and highly nonplanar nickel porphyrins in a non-coordinating solvent have previously revealed the first NiIII porphyrin dication. Herein, we investigate if these nonplanar porphyrins can also be used to detect the so far unobserved CuIII porphyrin dication. Electrochemical studies of the oxidation of (DPP)M and (OETPP)M show three processes, the first two of which are macrocycle centered to give the porphyrin dication followed by a CuII/III processes at more positive potential. Support for the assignment of the CuII/III process comes from the linear relationships observed between E1/2 and the third ionization potential of the central metal ions for Fe, Co, Ni and Cu complexes of (DPP)M and (OETPP)M. In addition, the oxidation behaviour of additional nonplanar nickel porphyrins is investigated in a non-coordinating solvent, with nickel meso-tetraalkylporphyrins also being found to form NiIII porphyrin dications. Finally, ...
http://www.tara.tcd.ie/handle/2262/73845
IJMS | Free Full-Text | Differential Antioxidant Responses and Perturbed Porphyrin Biosynthesis after Exposure to Oxyfluorfen...IJMS | Free Full-Text | Differential Antioxidant Responses and Perturbed Porphyrin Biosynthesis after Exposure to Oxyfluorfen...
We compared antioxidant responses and regulation of porphyrin metabolism in rice plants treated with oxyfluorfen (OF) or methyl viologen (MV). Plants treated with MV exhibited not only greater increases in conductivity and malondialdehyde but also a greater decline in Fv/Fm, compared to plants treated with OF. MV-treated plants had greater increases in activities of superoxide dismutase (SOD) and catalase (CAT) as well as transcript levels of SODA and CATA than OF-treated plants after 28 h of the treatments, whereas increases in ascorbate peroxidase (APX) activity and transcript levels of APXA and APXB were greater in OF-treated plants. Both OF- and MV-treated plants resulted in not only down-regulation of most genes involved in porphyrin biosynthesis but also disappearance of Mg-porphyrins during the late stage of photooxidative stress. By contrast, up-regulation of heme oxygenase 2 (HO2) is possibly part of an efficient antioxidant response to compensate photooxidative damage in both treatments. Our
http://www.mdpi.com/1422-0067/16/7/16529
Porphyrin metabolism | LAMP
Porphyrins are organic aromatic compounds composed of four pyrrole rings interconnected to each other and to the Fe2+ ion. Porphyrins are essential cofactors of many proteins including cytochrome proteins and haemoglobin and myoglobin in humans. The first step in the production of porphyrin in animals is the mitochondrial formation of delta-aminolevulinate from glycine and succinyl-CoA. In humans, this aminolevulinate is then transported to cytosol where the 4-step conversion into Coproporphyrinogen III occurs. The remaining processing of this intermediate to protoporphyrin IX and then to heme takes place in mitochondrion.. The cytochrome proteins in Plasmodium and Coccidian species such as Toxoplasma and Neospora require de novo synthesis of porphyrin. Although P. falciparum obtains heme from host haemoglobin digestion, it cannot utilise them for biosynthesis of its own porphyrin-containing proteins [1] and converts them to hemozoin [2]. The enzymes of de novo heme biosynthesis in P. falciparum ...
http://www.llamp.net/?q=Nca%20Porphyrin%20metabolism
Photosensitizing Effect of Porphyrin Films as Organic Photodetector - UNS Institutional RepositoryPhotosensitizing Effect of Porphyrin Films as Organic Photodetector - UNS Institutional Repository
Key words: Organic photosensitizer, natural porphyrin, titanium dioxide anatase, phorocurrent Abstract: A set of organic photodetector devices arranged as indium doped tin oxide (TTO)/porphyrin/TiOialuminum has been fabricated and its performance has been tested in dark and under various illumination of visible light intensity from 20-100 mW/cm2. Four devices were prepared using natural porphyrin by I, 3, 5 and 7 times of spin coating. First, porphyrin film was deposited onto indium doped tin oxide (!TO)-covered glass substrate by spin coating technique. Second, titanium dioxide (Ti02) film was deposited on top of the porphyrin film using similar technique. Porphyrin was isolated from spirulina microalgae and Ti02 nanoparticle was prepared by controlled hydrolysis technique using titanium(IV) etoxide, Ti(OC2Hj)4, and potassium chloride. The films were characterized by UV-vis spectrophotometer to investigate their absorption spectra. The porphyrin film has maximum absorbance at 660 nm, which is ...
https://eprints.uns.ac.id/11894/
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure - Fingerprint -...
Fingerprint Dive into the research topics of Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure. Together they form a unique fingerprint. ...
https://arizona.pure.elsevier.com/en/publications/design-and-synthesis-of-an-expanded-porphyrin-that-has-selectivit/fingerprints/
YEUNGNAM UNIVERSITY: Photoinduced Reduction of Manganese(III) meso-Tetrakis(1-methylpyridinium-4-yl)porphyrin at AT and GC Base...
The photoreduction of water-soluble cationic manganese (III) meso-tetrakis (1-methylpyridium-4-yl)porphyrin (Mn-III(TMPyP)(4+)) bound to a synthetic polynucleotide, either poly[d(A-T)(2)] or poly[d(G-C)(2)], was examined by conventional absorption and circular dichroism (CD) spectroscopy, transient absorption, and transient Raman spectroscopy. Upon binding, Mn-III(TMPyP)(4+) produced a positive CD signal for both polynucleotides, suggesting external binding. In the poly[d(A-T)(2)]-Mn-III(TMPyP)(4+) adduct case, an interaction between the bound porphyrin was suggested. The transient absorption spectral features of Mn-III(TMPyP)(4+) in the presence of poly[d(A-T)(2)] and poly[d(G-C)(2)] were similar to those of the photoreduced products, Mn-II(TMPyP)(4+), whereas Mn-III(TMPyP)(4+) in the absence of polynucleotides retained its oxidation state. This indicated that both poly[d(A-T)(2)] and poly[d(G-C)(2)] act as electron donors, resulting in photo-oxidized G and A bases. The transient Raman bands ...
http://ir.yu.ac.kr/handle/YU.REPOSITORY/29238
Dualism of sensitivity and selectivity of porphyrin dimers in electroanalysis - CONVERIS forskningsinformationssystem -...Dualism of sensitivity and selectivity of porphyrin dimers in electroanalysis - CONVERIS forskningsinformationssystem -...
This work uncovers the application of porphyrin dimers for the use in electroanalysis, such as potentiometric determination of ions. It also puts in question a current perception of an occurrence of the super-Nernstian response, as a result of the possible dimerization of single porphyrins within an ion-selective membrane. To study that, four various porphyrin dimers were used as ionophores, namely, freebase-freebase, Zn-Zn, Zn-freebase, and freebase-Zn. Since the Zn-freebase and freebase-Zn porphyrin dimers carried both anion- and cation-sensitive porphyrin units, their application in ISEs was utilized in both anion- and cation-sensitive sensors. With respect to the lipophilic salt added, both porphyrins dimers were found anion- and cation-sensitive. This allowed using a single molecule as novel type of versatile ionophore (anion- and cation-selective), simply by varying the membrane composition. All anion-sensitive sensors were perchlorate-sensitive, while the cation-selective sensors were ...
https://research.abo.fi/converis/portal/Publication/7612766?auxfun=&lang=sv_SE
Selection and amplification of mixed-metal porphyrin cages from dynamic combinatorial libraries
Mixed metallo-porphyrin cages were selected and amplified from dynamic combinatorial libraries (DCLs) by using appropriate templates. The cages are composed of two bisphosphine substituted zinc(II) porphyrins as ligand donors and two rhodium(III) or ruthenium(II) porphyrins as ligand acceptors, and are connected through metal-phosphorus coordination. Ru and Rh porphyrins that display a large structural diversity were employed. The templating was achieved by using 4,4-bpy, 3,3-dimethyl-4,4-bipyridine and benzo[lmn]-3,8-phenanthroline, and acts through zinc-nitrogen coordination. The absolute amount of amplification from the DCLs is strongly dependent on the combination of the Ru/Rh porphyrin and the template; cages with sterically demanding porphyrins can only form with smaller templates. In the case of tert-butyl-substituted TPP (TPP=tetraphenylporphyrin), cages are not formed at all. The formation of the cages is usually complete within 24 h at an ambient temperature; in the case of the cage ...
https://curis.ku.dk/portal/da/publications/selection-and-amplification-of-mixedmetal-porphyrin-cages-from-dynamic-combinatorial-libraries
Myc Proto Oncogene Protein Pipeline Landscape - Rohtak News MagazineMyc Proto Oncogene Protein Pipeline Landscape - Rohtak News Magazine
Table of contents 1. Report Introduction. 2. Myc Proto Oncogene Protein 3. Myc Proto Oncogene Protein Current Treatment Patterns. 4. Myc Proto Oncogene Protein - DelveInsights Analytical Perspective. 5. Therapeutic Assessment. 6. Myc Proto Oncogene Protein Late Stage Products (Phase-III). 7. Myc Proto Oncogene Protein Mid Stage Products (Phase-II). 8. Early Stage Products (Phase-I). 9. Pre-clinical Products and Discovery Stage Products. 10. Inactive Products. 11. Dormant Products. 12. Myc Proto Oncogene Protein Discontinued Products. 13. Myc Proto Oncogene Protein Product Profiles. 14. Myc Proto Oncogene Protein Key Companies. 15. Myc Proto Oncogene Protein Key Products. 16. Dormant and Discontinued Products. 17. Myc Proto Oncogene Protein Unmet Needs. 18. Myc Proto Oncogene Protein Future Perspectives. 19. Myc Proto Oncogene Protein Analyst Review 20. Appendix. 21. Report Methodology. Request Sample Pages @ Myc Proto Oncogene Protein Clinical Trials. Media Contact ...
http://www.rohtaknewsmagazine.net/story/132576/myc-proto-oncogene-protein-pipeline-landscape.html
Use of Green Porphyrins to Treat Neovasculature in the Eye - Patent applicationUse of Green Porphyrins to Treat Neovasculature in the Eye - Patent application
0020] In one preferred embodiment, the green porphyrin is prepared as a liposomal formulation. Liposomal formulations are believed to deliver the green porphyrin selectively to the low-density lipoprotein component of plasma which, in turn acts as a carrier to deliver the active ingredient more effectively to the neovasculature. Increased numbers of LDL receptors have been shown to be associated with neovascularization, and by increasing the partitioning of the green porphyrin into the lipoprotein phase of the blood, it appears to be delivered more efficiently to the neovasculature. Green porphyrins, and in particular BPD-MA, strongly interact with such lipoproteins. LDL itself can be used as a carrier, but LDL is considerably more expensive and less practical than a liposomal formulation. LDL, or preferably liposomes, are thus preferred carriers for the green porphyrins since green porphyrins strongly interact with lipoproteins and are easily packaged in liposomes. Compositions of green ...
http://www.patentsencyclopedia.com/app/20110137228
Innovative approach in Legionella water treatment with photodynamic cationic amphiphilic porphyrin | Water Supply | IWA...Innovative approach in Legionella water treatment with photodynamic cationic amphiphilic porphyrin | Water Supply | IWA...
Thermal water treatment with temperatures higher than 50 °C, UV radiation, use of disinfectants, and treatment with chlorine, ozone or chlorodium oxide are the basic techniques for the removal of Legionella from water systems (Kuchta et al. 1985; Bédard et al. 2016). Despite the implementation of all these methods, legionellosis is becoming more frequent, so it is necessary to use new approaches in water disinfection. One of the new approaches is the use of antimicrobial photodynamic therapy (aPDT) as a disinfection method of tap water. The effect of the recently described cationic porphyrin with lipophilic moiety was investigated to determine its antibacterial activity against the opportunistic plumbing pathogen Legionella in its natural environment, tap water. A recent overview of the development and use of amphiphilic porphyrins in PDT emphasized the need for further investigation of cationic porphyrins with different lipophilic moieties as this class of compounds has shown a promising ...
https://iwaponline.com/ws/article/19/5/1473/65546/Innovative-approach-in-Legionella-water-treatment
Near-field spectroscopy of water-soluble and water-insoluble porphyrin J-aggregates<...
TY - JOUR. T1 - Near-field spectroscopy of water-soluble and water-insoluble porphyrin J-aggregates. AU - Nagahara, Tetsuhiko. AU - Imura, Kohei. AU - Okamoto, Hiromi. PY - 2004/11/1. Y1 - 2004/11/1. N2 - Mesoscopic properties of J-aggregates of water-soluble [tetrakis(4- sulfonatophenyl)porphyrin] and water-insoluble [tetrakis(4-methoxyphenyl) porphyrin and tetraphenylporphyrin] tetraphenylporphyrin derivatives in thin films have been investigated by scanning near-field optical microscopy. From surface topography, the sample films were found to be composed of planar J-aggregate microcrystallines. The transmittance spectra of the water-insoluble samples are site specific, while those of the water-soluble samples are not. This observation might reflect the spatial inhomogeneity of the thin films in mesoscopic scales and is related to the broad J-bands of water-insoluble samples. Excited state lifetimes, obtained from time-resolved, pump-probe measurements in small domains, were in the 30-70 ps ...
https://waseda.pure.elsevier.com/en/publications/near-field-spectroscopy-of-water-soluble-and-water-insoluble-porp
Synthetic aspects of carbazole containing porphyrins and porphyrinoidsSynthetic aspects of carbazole containing porphyrins and porphyrinoids
Porphyrins are tetrapyrrolic aromatic macrocycles and ubiquitous in nature. They are excellent dyes with strong absorption in the visible region (400�700 nm) and they exhibit decent fluorescence in the red region (620�900 nm). Carbazole is a nitrogen-containing electron rich aromatic heterocycle which can be linked to porphyrins and other chromophores. This review provides an overview of the different synthetic strategies that have been employed to prepare carbazole-substituted porphyrins and carbazole-fused porphyrinoids and similar systems. It also shows that how the substitution of carbazole occurs on the porphyrin core can alter its optical and electronic features. Introduction of carbazole moieties in the porphyrin ring resulted in fused porphyrinoids with changed aromaticity and significantly altered electronic features of the molecules ...
http://repository.iitgn.ac.in/handle/123456789/4487
Boron porphyrin and corrole complexes - Journal of Chemistry BlogBoron porphyrin and corrole complexes - Journal of Chemistry Blog
The chemistry of boron porphyrins, which are unique in containing two boron atoms per porphyrin ligand. Highlights have been the development of a series of complexes, a diboryl porphyrin, a diboranyl porphyrin containing a B-B bond which forms through spontaneous reductive coupling of the diboryl under certain conditions ...
http://journalofchemistry.org/wpblog/2016/11/05/boron-porphyrin-and-corrole-complexes/
Oligo- and polypeptide conjugates of cationic porphyrins: binding, cellular uptake, and cellular localization - Repository of...Oligo- and polypeptide conjugates of cationic porphyrins: binding, cellular uptake, and cellular localization - Repository of...
Recently, we have characterized the DNA and nucleoprotein (NP) binding of bis(4-N-methylpyridyl)-15,20-di(4-carboxyphenyl)porphyrin (BMPCP) and meso-tri(4-N-methylpyridyl)-mono(4-carboxyphenyl)porphyrin (TMPCP) and their tetrapeptide conjugates (BMPCP-4P2 and TMPCP-4P, respectively). In this work, we investigated the interaction of TMPCP conjugated to the tetrapeptide branches of branched chain polymeric polypeptide with poly-l-lysine backbone (AK) with DNA or NP using spectroscopic methods. Analysis of absorption spectra revealed the external binding but no intercalation of TMPCP-AK to DNA. There was no evidence for the interaction between TMPCP-AK and encapsidated DNA. Furthermore, we examined the cellular uptake of BMPCP and TMPCP and their tetra- or polypeptide conjugates by flow cytometry and analyzed how charge, size, and structure of the compounds affect their incorporation. In comparison, liposomal association constants of these derivatives were determined. BMPCP-4P2 accumulated the ...
http://real.mtak.hu/79588/
Nitration of Halterman porphyrin: a new route for fine tuning chiral iron and manganese porphyrins with application in...Nitration of Halterman porphyrin: a new route for fine tuning chiral iron and manganese porphyrins with application in...
A methodology is reported for the regioselective nitration of the phenyl groups of Halterman porphyrin, using NaNO2. These nitro-porphyrins can be reduced to aminoporphyrins and then N-dimethylated to give new optically active porphyrins. Applications to the asymmetric epoxidation of styrene derivatives by H2O2 to give optically active epoxides (ee up to 60%) and hydroxylation of alkanes to give optically active secondary alcohols (ee up to 69%) were carried out in organic solvents (dichloromethane/methanol) using chiral iron and manganese porphyrins as catalysts.
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01116078
Cytotoxicity of a Novel Porphyrin Compound with Potential for Use in P by Christina King Smith
King-Smith, Christina, Laura Black, Matthew Mawhinney, Jan Habdas, and Piotr Habdas. Cytotoxicity of a Novel Porphyrin Compound with Potential for Use in Photodynamic Therapy. Amer. Soc. of Cell Biology. San Francisco. Dec. 2008. Conference Presentation.. ...
http://scholarship.sju.edu/bio_fac/730/
Nanostructured assembly of porphyrin clusters for light energy conversion<...
TY - JOUR. T1 - Nanostructured assembly of porphyrin clusters for light energy conversion. AU - Hasobe, Taku. AU - Imahori, Hiroshi. AU - Fukuzumi, Shunichi. AU - Kamat, Prashant V.. PY - 2003/10. Y1 - 2003/10. N2 - Free base porphyrin molecules form well-defined and ordered nanoclusters in mixed solvents with absorption characteristics that significantly differ from those of the monomer form. These self-assembled crystallites in acetonitrile/toluene (9:1, v/v) can be deposited as thin films on a nanostructured TiO2 electrode using an electrophoretic technique. This porphyrin cluster assembly is highly photoactive and capable of undergoing charge separation under visible light excitation. Photoexcitation of the porphyrin film electrode assembly in a photoelectrochemical cell with visible light produces relatively high photocurrent generation. A maximum photocurrent of 0.15 mA cm-2 and a photovoltage of 250 mV were attained using the I3-/I- redox couple. The electron flow to the TiO2 electrode ...
https://keio.pure.elsevier.com/en/publications/nanostructured-assembly-of-porphyrin-clusters-for-light-energy-co
Synthesis and Characterization of Novel Fluoro-glycosylated Porphyrins that can be Utilized as Theranostic AgentsSynthesis and Characterization of Novel Fluoro-glycosylated Porphyrins that can be Utilized as Theranostic Agents
Organic compounds that interact both with certain biological targets and display specific photophysical properties can be utilized as molecular tools to visualize and possibly effect disease related processes taking place in living organisms. In this regard, porphyrins are a class of naturally occurring molecules that possess intriguingly interesting photophysical properties where they can act as luminescent probes by emitting detectable light, as well as photosensitizers in the light mediated therapy called photodynamic therapy. In this thesis, the porphyrin structure has been synthetically combined with other molecule classes to achieve compounds with desirable multimodal characteristics.. Firstly, luminescent conjugated oligothiophenes (LCOs) that have extensively, and with great success, been utilized as fluorescent ligands for amyloid formations, have been conjugated to porphyrins to render oligothiophene porphyrin hybrids (OTPHs) comprising two optically active modalities. When applied as ...
http://liu.diva-portal.org/smash/record.jsf?pid=diva2%3A1239704&c=5&searchType=SIMPLE&language=sv&query=&af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22authority-person%3A23402+OR+0000-0002-5582-140X%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
2. Supramolecular chemistry of Rh(III) porphyrin
The coordination chemistry of Rh(III) porphyrin was outlined by Sadasivan and Fleischer in 1967.199,200 Their Rh(III) porphyrin, obtained by a metallation reaction using [Rh(CO)2Cl]2 and aerial oxidation, was believed to coordinate a labile water molecule which could be displaced by pyridine. A coordinated chloride counterion could be exchanged for azide, cyanide or hydroxide. Work by other groups has demonstrated that six coordinate Rh(III) porphyrins with two identical axial ligands may be generated by reaction of Rh(III)Cl porphyrins (OEP, TPP) with Ag+ to remove the chloride anion, followed by treatment with ligands such as BuNC, PPh2Me and POMe3.201,290 Reaction of Rh(III)Cl porphyrins with organolithium reagents232 or metal carbonylate anions202 afforded organometallic and metal-metal bonded derivatives respectively. The [(OEP)Rh]+ intermediate formed by treatment of (OEP)RhCl with AgBF4 was found to be active in electrophilic aromatic substitution reactions to afford s-bonded Rh aryl ...
http://jredman.kombyonyx.com/Ch20.htm
Directly Diphenylborane-Fused Porphyrins<...Directly Diphenylborane-Fused Porphyrins<...
TY - JOUR. T1 - Directly Diphenylborane-Fused Porphyrins. AU - Fujimoto, Keisuke. AU - Oh, Juwon. AU - Yorimitsu, Hideki. AU - Kim, Dongho. AU - Osuka, Atsuhiro. PY - 2016/2/24. Y1 - 2016/2/24. N2 - Mono- and bis(diphenylborane)-fused porphyrins were synthesized from the corresponding β-(2-trimethylsilylphenyl)-substituted porphyrins through the sequence of Si-B exchange reaction, intramolecular bora-Friedel-Crafts reaction, and ring-closing Si-B exchange reaction. Effective electronic interactions of the empty p-orbital of the boron atom with the porphyrin π-circuit lead to red-shifted absorption spectra and substantially decreased LUMO energy levels. Pyridine adds at the boron center to cause disruption of the electronic interaction of the boron atom with large association constants (1.9-17×104 m−1) depending on the central metal at the porphyrin. The ZnII complex behaved as a hetero-dinuclear Lewis acid, exhibiting regioselective binding of pyridines at the boron or the zinc ...
https://yonsei.pure.elsevier.com/en/publications/directly-diphenylborane-fused-porphyrins
Detection of unusual ΔHOMO | ΔLUMO relationship in tetrapyrrolic cis- and trans-doubly N-confused porphyrins<...
TY - JOUR. T1 - Detection of unusual ΔHOMO , ΔLUMO relationship in tetrapyrrolic cis- and trans-doubly N-confused porphyrins. AU - Muranaka, Atsuya. AU - Homma, Shigetsugu. AU - Maeda, Hiromitsu. AU - Furuta, Hiroyuki. AU - Kobayashi, Nagao. PY - 2008/7/30. Y1 - 2008/7/30. N2 - A plus-to-minus MCD sign in ascending energy has been detected for the Q bands of the copper(III) complexes of doubly N-confused porphyrin (cis- and trans-1). An unusual ΔHOMO , ΔLUMO relationship for tetrapyrrolic porphyrins was calculated using the HF, DFT, and semi-empirical methods. By applying the Michls perimeter model, the observed MCD pattern was successfully explained by the computational results.. AB - A plus-to-minus MCD sign in ascending energy has been detected for the Q bands of the copper(III) complexes of doubly N-confused porphyrin (cis- and trans-1). An unusual ΔHOMO , ΔLUMO relationship for tetrapyrrolic porphyrins was calculated using the HF, DFT, and semi-empirical methods. By applying the ...
https://kyushu-u.pure.elsevier.com/en/publications/detection-of-unusual-%CE%B4homo-lt-%CE%B4lumo-relationship-in-tetrapyrrolic
Porphyrins - blood. Causes, symptoms, treatment Porphyrins - blood
Description of disease Porphyrins - blood. Treatment Porphyrins - blood. Symptoms and causes Porphyrins - blood Prophylaxis Porphyrins - blood
http://drugline.org/ail/pathography/601/
Time Course of Retinal Dysfunction Following Verteporfin PDT in Rats: An Electroretinography (ERG), NaF Angiography and Optical...Time Course of Retinal Dysfunction Following Verteporfin PDT in Rats: An Electroretinography (ERG), NaF Angiography and Optical...
Abstract: : Purpose:To evaluate the effects of Verteporfin PDT on retinal function in the normal rat. Methods:Brown Norway rats weighing 250-300 grams were used. Animals were anesthetized with 12 mg /100 g tribromoethanol ip for each procedure. Verteporfin PDT: A bolus injection of verteporfin was administered into a cannulated femoral vein at 0.2 mg/kg (equivalent to the clinical dose by body weight). Five minutes following dye administration, the right eye was irradiated with a 689 nm diode laser at 50 J/cm2, 600 mW/cm2 and a spot size of 4 mm (at the cornea) centered on the optic nerve head. ERG: Rats were dark-adapted for 15 minutes, connected to bilateral cornea electrodes and stimulated using a LKC Ganzfeld electrophysiology system, and followed-up (FU) at 4 hours, and Days 1, 2 and 5 post-PDT. OCT: Horizontal scans were made across the optic nerve and retinal thickness measurements were assessed on either side of the nerve head and averaged using a Zeiss Humphrey OCT II system; FU was at ...
http://iovs.arvojournals.org/article.aspx?articleid=2420080
Electron Transfer in Ruthenium/Zinc Porphyrin Derivatives of Recombinant Human Myoglobins. Analysis of Tunneling Pathways in...Electron Transfer in Ruthenium/Zinc Porphyrin Derivatives of Recombinant Human Myoglobins. Analysis of Tunneling Pathways in...
TY - JOUR. T1 - Electron Transfer in Ruthenium/Zinc Porphyrin Derivatives of Recombinant Human Myoglobins. Analysis of Tunneling Pathways in Myoglobin and Cytochrome c. AU - Casimiro, Danilo R.. AU - Wong, Luet L.. AU - Colón, Jorge L.. AU - Zewert, Thomas E.. AU - Richards, John H.. AU - Chang, I. Jy. AU - Winkler, Jay R.. AU - Gray, Harry B.. PY - 1993/2/1. Y1 - 1993/2/1. N2 - Site-directed mutants of human myoglobin have been prepared and characterized; each protein has a single surface-modifiable histidine (at position 48, 70, or 83). The proteins were modified by covalent attachment of pentaammineruthenium (a5Ru) to the surface histidine and substitution of zinc mesoporphyrin IX diacid (ZnP) for the heme. Donor-acceptor separations (edge-edge distances d) in the modified proteins are 9.5 Å, His70; 12.7 Å, His48; and 15.5 Å, His83. Rates of photoinduced electron transfer in these ruthenium-modified myoglobins were measured by transient absorption spectroscopy. The 3ZnP*→ Ru3+ rate ...
https://scholar.lib.ntnu.edu.tw/en/publications/electron-transfer-in-rutheniumzinc-porphyrin-derivatives-of-recom
NAVER 학술정보 | Polarographic and Voltammetric Determination of meso-Tetrakis(4-sulfonatophenyl)porphyrin Tetrasodium Salt at...NAVER 학술정보 | Polarographic and Voltammetric Determination of meso-Tetrakis(4-sulfonatophenyl)porphyrin Tetrasodium Salt at...
The electrochemical behavior of meso-tetrakis(4-sulfonatophenyl) porphyrin tetrasodium salt (TPPS4) was investigated in aqueous media of BR buffer in pH range 2-12. Modern electroanalytical methods, i.e DC tast polarography (DCTP) and differential pulse polarography (both at a dropping mercury electrode), differential pulse voltammetry, adsorptive stripping voltammetry, and cyclic voltammetry (all at a hanging mercury drop electrode) were used for this purpose. TPPS4 gives three cathodic signals for pH 2 - 12, first of them corresponding to a two electron quasireversible process. From these signals, the first two are suitable for the determination of TPPS4 using both polarographic methods with limit of determination about 2·10-6 mol L-1 in BR buffer, pH 10. At concentration higher than 3·10-6 mol L-1, the calibration curve of the first signal deviates from the linear course due to formation of aggregates of TPPS4 in solution. The lowest limit of determination, 5.1·10-7 mol L-1 was achieved by AdSV
http://academic.naver.com/article.naver?doc_id=81410686
DNA-ligand interactions : a biophysical study of 9-hydroxyellipticine, Hoechst 33258 and a meso-substituted porphyrin...DNA-ligand interactions : a biophysical study of 9-hydroxyellipticine, Hoechst 33258 and a meso-substituted porphyrin...
Ismail, Matthew Arif (1998) DNA-ligand interactions : a biophysical study of 9-hydroxyellipticine, Hoechst 33258 and a meso-substituted porphyrin derivative binding to DNA. PhD thesis, University of Warwick. ...
http://wrap.warwick.ac.uk/4314/
Enhanced intersystem crossing in donor/acceptor systems based on zinc/iron or free-base/iron porphyrins | Read by QxMDEnhanced intersystem crossing in donor/acceptor systems based on zinc/iron or free-base/iron porphyrins | Read by QxMD
The deactivation pathways of the singlet excited state of a series of zinc or free-base donor porphyrins covalently linked by a bridge to a paramagnetic iron(III) chloride porphyrin acceptor have been studied. These donor-bridge-acceptor systems all share a similar geometry (25 A donor-acceptor center-to-center distance), but the bridges vary in electronic structure. In previously reported investigations of zinc/iron porphyrin systems, the fluorescence quenching of the donor has predominantly been assigned to electron transfer. However, for the porphyrin systems studied in this paper, we show that the dominant deactivation channels are enhanced intersystem crossing and singlet energy transfer. In both series, the intersystem crossing rate (S1--,T1) of the donor moiety is almost doubled in the presence of a paramagnetic high-spin metal-porphyrin acceptor. The significant spectral overlap of the donor fluorescence and acceptor absorption in both series allows for efficient singlet energy transfer ...
https://read.qxmd.com/read/11411985/enhanced-intersystem-crossing-in-donor-acceptor-systems-based-on-zinc-iron-or-free-base-iron-porphyrins
Early detection of colorectal adenocarcinoma: a clinical decision support tool based on plasma porphyrin accumulation and risk...Early detection of colorectal adenocarcinoma: a clinical decision support tool based on plasma porphyrin accumulation and risk...
An increase in naturally-occurring porphyrins has been described in the blood of subjects bearing different kinds of tumors, including colorectal, and this is probably related to a systemic alteration of heme metabolism induced by tumor cells. The aim of our study was to develop an artificial neural network (ANN) classifier for early detection of colorectal adenocarcinoma based on plasma porphyrin accumulation and risk factors. We measured the endogenous fluorescence of blood plasma in 100 colorectal adenocarcinoma patients and 112 controls using a conventional spectrofluorometer. Height, weight, personal and family medical history, use of alcohol, red meat, vegetables and tobacco were all recorded. An ANN model was built up from demographic data and from the integral of the fluorescence emission peak in the range 610-650 nm. We used the Receiver Operating Characteristic (ROC) curve to assess performance in distinguishing colorectal adenocarcinoma patients and controls. A liquid chromatography-high
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-018-4754-2
Vibronic coupling between Soret and higher energy excited states in iron(II) porphyrins: Raman excitation profiles of A<sub>2g<...Vibronic coupling between Soret and higher energy excited states in iron(II) porphyrins: Raman excitation profiles of A<sub>2g<...
TY - JOUR. T1 - Vibronic coupling between Soret and higher energy excited states in iron(II) porphyrins. T2 - Raman excitation profiles of A2g modes in the Soret region. AU - Egawa, Tsuyoshi. AU - Suzuki, Noriyuki. AU - Dokoh, Takashi. AU - Higuchi, Tsunehiko. AU - Shimada, Hideo. AU - Kitagawa, Teizo. AU - Ishimura, Yuzuru. PY - 2004/1/29. Y1 - 2004/1/29. N2 - Resonance Raman spectra were observed for heme proteins and iron(II) porphyrins including ferrous-CO and ferrous-isocyanide derivatives of cytochrome P450cam, a synthetic iron(II) porphyrin complex having a thiolate axial ligand, ferrous-isocyanide derivative of myoglobin, and synthetic iron(II) porphyrin complexes having either an imidazole or a sulfide axial ligand. Among them, the former three were found to be a hyperporphyrin, giving red and blue Soret absorption bands, whereas others were normal porphyrins giving a single Soret band. When Raman scattering was excited within the Soret region, an anomalously polarized (ap) Raman line, ...
https://einstein.pure.elsevier.com/en/publications/vibronic-coupling-between-soret-and-higher-energy-excited-states--2
Porphyrins & Bile Pigments | Harpers Illustrated Biochemistry, 30e | AccessMedicine | McGraw-Hill MedicalPorphyrins & Bile Pigments | Harpers Illustrated Biochemistry, 30e | AccessMedicine | McGraw-Hill Medical
The biochemistry of the porphyrins and of the bile pigments are closely related topics. Heme is synthesized from porphyrins and iron, and the products of degradation of heme are the bile pigments and iron. The biochemistry of the porphyrins and of heme is basic to understanding the varied functions of hemoproteins, and the porphyrias, a group of diseases caused by abnormalities in the pathway of porphyrin biosynthesis. A much more common clinical condition is jaundice, a consequence of an elevated level of plasma bilirubin, due either to overproduction of bilirubin or to failure of its excretion. Jaundice occurs in numerous diseases ranging from hemolytic anemias to viral hepatitis and to cancer of the pancreas. ...
http://accessmedicine.mhmedical.com/content.aspx?bookid=1366§ionid=73244643
Synthetic Porphyrins/Metalloporphyrins Which Mimic States in Catalytic Cycle of Cytochrome P-450 and Peroxidases<...Synthetic Porphyrins/Metalloporphyrins Which Mimic States in Catalytic Cycle of Cytochrome P-450 and Peroxidases<...
TY - JOUR. T1 - Synthetic Porphyrins/Metalloporphyrins Which Mimic States in Catalytic Cycle of Cytochrome P-450 and Peroxidases. AU - DAEID, N N AU - ATKINSON, S T AU - NOLAN, K B PY - 1993/7. Y1 - 1993/7. N2 - The reaction of thiolates, RS-, having electron withdrawing groups with iron(III) tetra-arylporphyrins in DMSO,in air gives low-spin Fe(III)-P(-SR)2, having hyperporphyrin spectra similar to thiolate derivatives of cytochrome P-450. Removal of air gives high spin Fe(II)-P(-SR) which on addition of CO results in H+ uptake and formation of Fe(II)-P(SHR)CO. Addition of thiols and base to the iron(III) porphyrins in toluene in the absence of air gives 4-coordinate Fe(II)-P which in the presence of CO gives Fe(II)-P(SHR)CO. Metal complexes of one of the porphyrins studied i.e. a tetraphenolic porphyrin undergo 2e- oxidation in air to give quinonoid species which oxidise peroxidase substrates. Rate constants for some of these reactions are reported.. AB - The reaction of thiolates, RS-, having ...
https://pureportal.strath.ac.uk/en/publications/synthetic-porphyrinsmetalloporphyrins-which-mimic-states-in-catal
Synthesis and characterization of halogeno- and pseudo-halogeno-thallium(III) porphyrin complexes. Variation of the co...
TY - JOUR. T1 - Synthesis and characterization of halogeno- and pseudo-halogeno-thallium(III) porphyrin complexes. Variation of the co-ordination geometry as a function of the axial ligand. AU - Senge, Mathias O.. AU - Ruhlandt, Karin. AU - Regli, Kevin J.. AU - Smith, Kevin M.. PY - 1993. Y1 - 1993. N2 - Several thallium(III) porphyrin complexes [Tl(por)X] with the axial ligand X = MeCO2, CF3CO2, Cl, Br, I, CN, SCN or N3, have been obtained via ligand-exchange reactions from the corresponding thallium(III) trifluoroacetates. All compounds were characterized by 1H NMR, UV/VIS spectroscopy, and elemental analysis. Fourteen compounds were investigated in detail by X-ray crystallography to obtain information on the influence of the axial ligand on the macrocycle core conformation in main-group metalloporphyrins and to establish the molecular stereochemistry of thallium(III) porphyrins with cyano, acetato, thiocyanato, bromo, iodo and azido groups as axial ligands.. AB - Several thallium(III) ...
https://experts.syr.edu/en/publications/synthesis-and-characterization-of-halogeno-and-pseudo-halogeno-th
Spectroscopic and Computational Studies of Porphyrins Utilised in Photovoltaic DevicesSpectroscopic and Computational Studies of Porphyrins Utilised in Photovoltaic Devices
The work presented in this thesis encompasses an investigation into a number of porphyrin species. All of this work has a central focus on analysis of the porphyrin electronic structure and within the context of photovoltaics. The first exemplar of structures encompasses a series of Zn(II) tetraphenyl porphyrins which have asymmetrically substituted meso groups. The dihedral angle between the porphyrin macrocycle and the meso binding functionality has been shown not to infer any insulating properties towards delocalisation of the excited state. It is proposed that the electron withdrawing ability of the carboxylate unit is more than sufficient to overcome the poor π-overlap between the aromatic units. The inclusion of redox active functionalities at the distal meso site is shown to affect the energy and nature of the oxidised porphyrin species. It does so without almost any effect to the excited state properties of the structure. Both of these findings are important within the context of ...
https://ourarchive.otago.ac.nz/handle/10523/2340
EFFECT OF HYPERPROLACTINEMIA INDUCED BY PITUITARY GRAFTS OR CASTRATION ON PORPHYRIN CONTENT OF THE MOUSE HARDERIAN GLAND
Japans largest platform for academic e-journals: J-STAGE is a full text database for reviewed academic papers published by Japanese societies
https://www.jstage.jst.go.jp/article/jts/26/3/26_3_151/_article/-char/en
Strong π-π Interaction of porphyrins on (6,5) carbon nanotubes with full surface coverage: Ab-initio calculations<...Strong π-π Interaction of porphyrins on (6,5) carbon nanotubes with full surface coverage: Ab-initio calculations<...
TY - JOUR. T1 - Strong π-π Interaction of porphyrins on (6,5) carbon nanotubes with full surface coverage. T2 - Ab-initio calculations. AU - Orellana, Walter. PY - 2014. Y1 - 2014. N2 - The stability, electronic, and optical properties of (6,5) single-walled carbon nanotubes (CNTs) functionalized with free-base tetraphenylporphyrin (TPP) molecules through π-stacking interactions are studied by ab-initio calculations. The stability and optical response of the CNT-TPP compounds for increasing CNT-surface coverage are investigated. Our results show that four TPP molecules forming a ring around the CNT is the most stable configuration, showing strong binding energies of about 2.5 eV/TPP. However, this binding energy can increase even more after additional molecules assemble side by side along the CNT, favoring the formation of a full single layer of TPP, as experimentally suggested. The strong π-π attractive forces induce molecular distortions that move the TPP higher-occupied molecular orbital ...
https://researchers.unab.cl/es/publications/strong-%CF%80-%CF%80-interaction-of-porphyrins-on-65-carbon-nanotubes-with-
Complete Double Epoxidation of Divinylbenzene Using Mn(porphyrin)-Based Porous Organic Polymers<...
TY - JOUR. T1 - Complete Double Epoxidation of Divinylbenzene Using Mn(porphyrin)-Based Porous Organic Polymers. AU - Zhang, Kainan. AU - Farha, Omar K.. AU - Hupp, Joseph T.. AU - Nguyen, Son Binh T.. PY - 2015/8/7. Y1 - 2015/8/7. N2 - A series of porphyrin-based porous organic polymers (PPOPs) were synthesized in excellent yields via the Yamamoto-Ullmann couplings of tetrabromo spirobifluorene with several brominated porphyrin monomers. After isolation and demetalation, the metal-free PPOP can be postsynthetically metalated to form a MnIII-PPOP that is catalytically active toward the selective double-epoxidation of divinylbenzene to divinylbenzene dioxide. (Chemical Equation Presented).. AB - A series of porphyrin-based porous organic polymers (PPOPs) were synthesized in excellent yields via the Yamamoto-Ullmann couplings of tetrabromo spirobifluorene with several brominated porphyrin monomers. After isolation and demetalation, the metal-free PPOP can be postsynthetically metalated to form a ...
https://sofi-northwestern.pure.elsevier.com/en/publications/complete-double-epoxidation-of-divinylbenzene-using-mnporphyrin-b
About the Cover | Molecular Cancer TherapeuticsAbout the Cover | Molecular Cancer Therapeutics
The Cover. cDNA microarray analysis of HeLa S3 cells treated with the G-quadruplex-interactive cationic porphyrin TMPyP4. Cells were treated with 100 µm TMPyP4 for 48 h, and mRNA was used to probe a 500-gene array. The expression of a number of oncogenes, including c-FOS, JUN-B, c-MYB, STAT-1, and c-MYC, was decreased specifically by this agent, and not by its positional isomer TMPyP2, which interacts with G-quadruplex DNA very poorly. The c-MYC oncogene is one of the most consistently down-regulated genes in this study and bears a sequence in its promoter that forms a G-quadruplex structure in vitro. For details, see 565 in this issue. ...
https://mct.aacrjournals.org/content/1/8.cover-expansion
Structural Biochemistry/Protein function/Heme group - Wikibooks, open books for an open worldStructural Biochemistry/Protein function/Heme group - Wikibooks, open books for an open world
Heme is a porphyrin that is coordinated with Fe(II). One of the most important classes of chelating agents in nature are the porphyrins [1]. A porphyrin molecule can coordinate to a metal using the four nitrogen atoms as electron-pair donors. In the body, the iron in the heme is coordinated to the four nitrogen atoms of the porphyrin and also to a nitrogen atom from a histidine residue, one of the amino-acid residues in hemoglobin) of the hemoglobin proteins. The sixth protein, coordination site, around the iron of the heme is occupied by O2 when the hemoglobin is oxygenated. The heme group is nonplanar when it is not bound to oxygen [2]. The iron is pulled out of the plane of the porphyrin, towards the histidine residue to which it is attached. This nonplanar configuration is characteristic of the deoxygenated heme group, and is often referred to as being domed shape [2]. When the Fe heme group binds to an oxygen molecule, the porphyrin ring adopts a planar configuration and hence the Fe lies ...
https://en.wikibooks.org/wiki/Structural_Biochemistry/Protein_function/Heme_group
reagents-clinical-chemistry-porphyrin
Definition : Clinical chemistry reagents intended to perform qualitative and/or quantitative chemical analysis of body fluids (typically urine) to measure the total level of porphyrin. Analysis may include a profile of porphyrin components (e.g., uroporphyrin, coproporphyrin). Measurement of the total level of porphyrins is used in the diagnosis and management of one of a group of metabolic disorders, either inherited or acquired, usually known as porphyrias; measurement of the porphyrin-level profile in urine is used to characterize several specific diseases, such as porphyria cutanea tarda, that are associated with the presence of isocoproporphyrin. Some specific porphyrin analyses in whole blood are performed for screening purposes, such as zinc protoporphyrin for iron-deficiency anemia and free erythrocyteporphyrin determination for lead poisoning.. Entry Terms : ZPP (Zinc Protoporphyrin) Determination Reagents , Zinc Protoporphyrin (ZPP) Determination Reagents , Porphyrin Determination ...
http://productguide.ophthalmologymanagement.com/term/4737/reagents-clinical-chemistry-porphyrin
Free erythrocyte protoporphyrin as an indicator of the biological effect of lead in adult males - II. Comparison between Free...
TY - JOUR. T1 - Free erythrocyte protoporphyrin as an indicator of the biological effect of lead in adult males - II. Comparison between Free Erythrocyte Protoporphyrin and Other Indicators of Effect. AU - Alessio, L.. AU - Bertazzi, P. A.. AU - Monelli, O.. AU - Foà, V.. PY - 1976/6. Y1 - 1976/6. N2 - In previous research we established that FEP is a suitable and valid test for evaluating the metabolic damage caused by lead absorption. In this study, in the same sample consisting of adult male subjects with PbB levels ranging from 15 to 150 μg/100 ml, we examined the relationship existing between PbB and the other indicators of effect so as to compare their behavior with that of FEP and establish whether there is a field of application where the erythrocyte metabolite is to be preferred. FEP and ALAD displayed a very much better correlation with PbB than the urinary tests (ALAU and CPU). The decrease in ALAD values is already clear at PbB levels which do not cause an elevation of FEP; on the ...
https://moh-it.pure.elsevier.com/en/publications/free-erythrocyte-protoporphyrin-as-an-indicator-of-the-biological-3
Method of treating cancer tumors with imine porphyrin compounds by Dimitris Skalkos, Steven H. Selman et al.Method of treating cancer tumors with imine porphyrin compounds by Dimitris Skalkos, Steven H. Selman et al.
Purified imines of porphyrins, chlorins, bateriochlorins, chlorophylls, bacteriochlorophylls, purpurins, reduced purpurins, verdins, Diels Alder adducts, benzochlorins and metal complexes of the foregoing imines are disclosed. The formulas of the benzochlorinimines and of the benzochlorinimine metal complexes are set forth below: ##STR1## In specific examples, M in the metal complexes is a copper cation that is complexed with two of the nitrogens of the benzochlorinimine R and R are methyl, and R1 through R8 are ethyl.
http://utdr.utoledo.edu/utpatents/169/
Pollutant Removal in Water Using Porphyrin Based Metal-Organic Frameworks - 2014 MRS Fall Meeting - Materials Research Society
Water is one of the most important components for our life. Preservation of fresh water is one of the most important issues in sustainable development, which is called water treatment. In water treatment there are two main separated steps, separation and degradation. Many kinds of porous materials including zeolites and porous carbons were used for pollutant separation by adsorption. TiO2 was widely used for photocatalytic degradation of pollutant. Here we report new type of inorganic-organic hybrid porous material, metal-organic framework (MOF), which can adsorb pollutant from water followed by degradation of the pollutant by light irradiation. The MOF comprising porphyrin based ligand has good stability in water unlike most of MOFs. The MOF selectively adsorb a pollutant having smaller size than its pore size, which demonstrates size selective pollutant adsorption property of the MOF. In addition, porphyrin ligands decompose the adsorbed pollutant by visible light irradiation. Therefore, the ...
http://www.prolibraries.com/mrs/?select=session&sessionID=4951
Towards molecular scale mechano-electronic devices: porphyrin catenanes<...
TY - JOUR. T1 - Towards molecular scale mechano-electronic devices:. T2 - porphyrin catenanes. AU - Gunter, Maxwell J.. AU - Johnston, Martin R.. PY - 1992. Y1 - 1992. N2 - Using self-assembly strategies, catenanes consisting of zinc and free base porphyrins with hydroquinol-containing polyether straps of different lengths interlinked with a tetracationic bipyridinium cyclophane have been synthesised.. AB - Using self-assembly strategies, catenanes consisting of zinc and free base porphyrins with hydroquinol-containing polyether straps of different lengths interlinked with a tetracationic bipyridinium cyclophane have been synthesised.. UR - http://www.scopus.com/inward/record.url?scp=37049082995&partnerID=8YFLogxK. U2 - 10.1039/C39920001163. DO - 10.1039/C39920001163. M3 - Article. AN - SCOPUS:37049082995. SP - 1163. EP - 1165. JO - Journal of the Chemical Society, Chemical Communications. JF - Journal of the Chemical Society, Chemical Communications. SN - 0022-4936. IS - 17. ER - ...
https://researchnow.flinders.edu.au/en/publications/towards-molecular-scale-mechano-electronic-devices-porphyrin-cate
Textversion www.digitale-photographie.de
According to Greg Hillebrand, Ph.D., a recognized subject matter expert at P&G on the subject, there may be a real correlation between the amount of porphyrins and skin aging as described in the following technical excerpt that offers the best understanding we have today on the matter: In pilosebaceous follicles, porphyrins are produced by propionibacterium acnes (P. acnes) that are normal inhabitants of the human skin and the pilosebaceous ducts. Porphyrins are highly fluorescent pores containing P. acnes and the associated porphyrins appear red-orange when facial skin is illuminated with long wavelength UVA radiation. The intensity of the follicular fluorescence and its extent of facial involvement is known to be proportional to the density of P. acnes. Porphyrin fluorescence appears first on the nose and chin, and then increases in incidence through adulthood and declines after the age of 50, possibly reflecting the rate of sebum secretion. Porphyrins may also have cytotoxic and comedogenic ...
http://www.digitale-photographie.de/textversion.asp?dtl=T&lid=10&iid=188&mid=99&uid=52&change=T
ICPP 2015 | Cancelled: Days Program for Accompanying Persons - International Congress on Porphyrins and Porphyrias
Due to insufficient registrations we had to cancel the Dayʼs Program for Accompanying Persons Please contact us on-site for refund and information about individual sightseeing tours in Düsseldorf. ...
http://www.icpp2015.org/social-program/days-program-for-accompanying-persons
ICPP 2015 | Reception for all conference attendees - International Congress on Porphyrins and Porphyrias
At the end of the first day of the scientific meeting we invite you to a sponsored reception to join colleagues and friends for drinks and light appetizers in the congress venue, from 17.15 - 18.45 hours ...
http://www.icpp2015.org/social-program/reception-for-all-conference-attendees
Synthesis and aggregate formation of triphenylene core-centered porphyrin hexamers<...
TY - JOUR. T1 - Synthesis and aggregate formation of triphenylene core-centered porphyrin hexamers. AU - Hasobe, Taku. AU - Rabbani, Mohammad Gulam. AU - Sandanayaka, Atula S.D.. AU - Sakai, Hayato. AU - Murakami, Tatsuya. PY - 2010. Y1 - 2010. N2 - We demonstrate the synthesis, aggregate formation and spectroscopic property of new triphenylene core-centered porphyrin hexamers with different alkyl chain lengths.. AB - We demonstrate the synthesis, aggregate formation and spectroscopic property of new triphenylene core-centered porphyrin hexamers with different alkyl chain lengths.. UR - http://www.scopus.com/inward/record.url?scp=75649142119&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=75649142119&partnerID=8YFLogxK. U2 - 10.1039/b915983e. DO - 10.1039/b915983e. M3 - Article. C2 - 20107640. AN - SCOPUS:75649142119. VL - 46. SP - 889. EP - 891. JO - Chemical Communications. JF - Chemical Communications. SN - 1359-7345. IS - 6. ER - ...
https://keio.pure.elsevier.com/en/publications/synthesis-and-aggregate-formation-of-triphenylene-core-centered-p
Free Quantum Chemical Studies On Porphyrins, Fullerenes And Carbon Nanostructures 2013
Seeing that interaction with projections on any surface could be a powerful technology, in 1998 they had turned the GestureXtreme system on its head to invent the Worlds First Interactive Projected Surfaces. The GestureFX, (GestureFX) Japanese Annual IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, Helsinki, Finland, 1-5. Quality written sensitive ET of ideal Outsourcing Definitions. 2006 IEEE International Conference on Communications 4:1754-1759. OM fiction for clicking % shared browser in a free ad hoc cue. decision of cavity home in a sent 19th product number. IEEE Global Telecommunications Conference( Globecom06), San Francisco, CA. free active marketplace: A interpretation for Enhancing in competitive position. Digital Humanities 2006, Paris, France, 309. tourist products for Looking and including books for other scrutiny back. Digital Humanities 2006, Paris, France, 107. A gibt collection item and JPEG gripping minutes loading level. open formation on ...
http://vjvincent.com/wusage/book/free-Quantum-chemical-studies-on-porphyrins%2C-fullerenes-and-carbon-nanostructures-2013/
Proto | definition of proto by Medical dictionaryProto | definition of proto by Medical dictionary
Looking for online definition of proto in the Medical Dictionary? proto explanation free. What is proto? Meaning of proto medical term. What does proto mean?
https://medical-dictionary.thefreedictionary.com/proto
What is a porphyria? - Women Help Women ConsultationWhat is a porphyria? - Women Help Women Consultation
The porphyrias are a group of rare inherited or acquired disorders that result from a buildup of natural chemicals that produce porphyrin in your body. Porphyrins are essential for the function of hemoglobin - a protein in your red blood cells that links to porphyrin, binds iron, and carries oxygen to your organs and tissue. High levels of porphyrins can cause significant problems. 20. Porphyria mainly affects your nervous system, skin and other organs.. ...
https://consult.womenhelp.org/nl/page/513/what-is-a-porphyria
What is a porphyria? - Women Help Women ConsultationWhat is a porphyria? - Women Help Women Consultation
The porphyrias are a group of rare inherited or acquired disorders that result from a buildup of natural chemicals that produce porphyrin in your body. Porphyrins are essential for the function of hemoglobin - a protein in your red blood cells that links to porphyrin, binds iron, and carries oxygen to your organs and tissue. High levels of porphyrins can cause significant problems. 20. Porphyria mainly affects your nervous system, skin and other organs.. ...
https://consult.womenhelp.org/it/page/513/-
Skin Disease in Porphyria | Porphyria for Patients
In patients with porphyria, high levels of porphyrins may circulate in the blood and are deposited in the skin. Porphyrins are photoactive molecules, the property responsible for their fluorescence. When a light ray (particularly one with a wavelength in the ultraviolet range) strikes a porphyrin molecule, the energy of the light is absorbed by the molecule, and some of its electrons become more active (technically we say that they are promoted to a higher energy level). In due course, the molecule relaxes by allowing the promoted electrons to drop back to a normal energy level. To do so, they must give out the extra energy they contain. This is radiated out as heat and light. If this takes place in the skin, it causes damage. It is for this reason that the skin disease of porphyria is usually restricted to areas which are exposed to the sun, and that avoiding sun exposure is so important in preventing skin disease.. ...
http://www.porphyria-patients.uct.ac.za/ppa/about/skindiseases
A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of...A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of...
Participants received Verteporfin photodynamic therapy and 1 mg triamcinolone acetonide intravitreal injection at the baseline visit. After the baseline visit, these participants received Verteporfin and triamcinolone acetonide 1 mg at every 3 month visit up to Month 9 only if leakage was detected on the fluorescein angiogram. At the 1.5, 4.5, 7.5 and 10.5 month follow-up visits participants received a sham injection. Starting from Month 12, if patients experienced ≥ 10 letters vision loss from the previous visit, they were treated at the investigators discretion with available standard of care therapy ...
https://clinicaltrials.gov/ct2/show/NCT00242580
Need help understanding Urinary Porphyrin Profile test results - Autism Spectrum Disorders - ACN Latitudes ForumsNeed help understanding Urinary Porphyrin Profile test results - Autism Spectrum Disorders - ACN Latitudes Forums
I got back a Urinary Porphyrins test from the Laboratoire de Biologie Medicale in Paris France. The following things have been flaged. Uroporphyrins I &am...
https://latitudes.org/forums/topic/22146-need-help-understanding-urinary-porphyrin-profile-test-results/
Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors - Full Text View - ClinicalTrials...Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors - Full Text View - ClinicalTrials...
OUTLINE: This is a dose-escalation study. Patients are stratified according to tumor location (posterior fossa tumors vs all other brain tumors).. Patients receive benzoporphyrin monoacid ring A (BPD-MA) IV preoperatively. Approximately 3 hours after BPD-MA administration, patients undergo craniotomy with photoillumination of the tumor. Patients with tumors greater than 2 cm in diameter also undergo gross tumor resection.. Cohorts of 3-6 patients receive escalating doses of BPD-MA until the maximum tolerated dose (MTD) is determined. The MTD is defined as the dose immediately preceding that at which 2 of 3 or 2 of 6 patients experience dose-limiting toxicity. Three additional patients are treated at the MTD.. Patients are followed at 4 and 6 weeks, every 3 months for 1 year, every 6 months for 1 year, and then annually thereafter.. PROJECTED ACCRUAL: A minimum of 24 patients will be accrued for this study within 3 years. ...
https://clinicaltrials.gov/ct2/show/NCT00002647
Influence of axial substitution on the optical limiting properties of indium porphyrins | ScholarBank@NUSInfluence of axial substitution on the optical limiting properties of indium porphyrins | [email protected]
Optical limiting properties in CH2Cl2 solution of a series of axially substituted InTPP (indium tetraphenyl-porphyrin) and axially substituted InTTP (indium tetra-p-tolyl-porphyrin) are investigated using a 532 nm laser with a pulse duration of 5 ns. The axial substitutions include -Cl, -SCN, -SPh and -SPh(p-Me). The optical limiting measurements reveal that the optical limiting properties of the indium porphyrins are greatly influenced by the axially attached functional groups. A limiting threshold of 0.18 J/cm2 is achieved for TTPInSCN, which is the best optical limiting material in this report. Z-scan experiments are also conducted and confirm that the good optical limiting performance of these indium porphyrins is due to the large value of σex/σg ...
https://scholarbank.nus.edu.sg/handle/10635/95473
Sonodynamic therapy--a review of the synergistic effects of drugs and ultrasound. - Semantic ScholarSonodynamic therapy--a review of the synergistic effects of drugs and ultrasound. - Semantic Scholar
Sonodynamic therapy, the ultrasound dependent enhancement of cytotoxic activities of certain compounds (sonosensitizers) in studies with cells in vitro and in tumor bearing animals, is reviewed. The attractive features of this modality for cancer treatment emerges from the ability to focus the ultrasound energy on malignancy sites buried deep in tissues and to locally activate a preloaded sonosensitizer. Possible mechanisms of sonodynamic therapy include generation of sonosensitizer derived radicals which initiate chain peroxidation of membrane lipids via peroxyl and/or alkoxyl radicals, the physical destabilization of the cell membrane by the sonosensitizer thereby rendering the cell more susceptible to shear forces or ultrasound enhanced drug transport across the cell membrane (sonoporation). Evidence against the role of singlet oxygen in sonodynamic therapy is discussed. The mechanism of sonodynamic therapy is probably not governed by a universal mechanism, but may be influenced by multiple factors
https://www.semanticscholar.org/paper/Sonodynamic-therapy-a-review-of-the-synergistic-ef-Rosenthal-Sostaric/16b726b37eb9d83cd67e376ecdb25c183cf125ab
The first time scientists succeeded in attaching functional molecules with graphene | Graphene UsesThe first time scientists succeeded in attaching functional molecules with graphene | Graphene Uses
which are well-known because of their notable functional properties (for instance,. Many previous researchers focus on wet-chemical methods for attaching the molecules to the surface of the material. The TUM team, however, decided to take a different approach: The researchers were able to link porphyrin molecules to graphene in a controlled manner in an ultra-high vacuum using the catalytic properties of a silver surface on which the graphene layer rested. When heated, the porphyrin molecules lose hydrogen atoms at their periphery and can thus form new bonds with the graphene edges ...
http://www.graphene-uses.com/first-time-scientists-succeeded-attaching-functional-molecules-graphene/
Triplet state delocalization in a conjugated porphyrin dimer probed by transient electron paramagnetic resonance techniques -...Triplet state delocalization in a conjugated porphyrin dimer probed by transient electron paramagnetic resonance techniques -...
The delocalization of the photoexcited triplet state in a linear butadiyne-linked porphyrin dimer is investigated by time-resolved and pulse electron paramagnetic resonance (EPR) with laser excitation. The transient EPR spectra of the photoexcited triplet states of the porphyrin monomer and dimer
https://ora.ox.ac.uk/objects/uuid:d70246dc-f70b-4907-a60f-6207234dc217
Porphyrin-LEGO®: synthesis of a hexafullereno-diporphyrin using porphyrins programmed for [4+2]-cycloaddition - Chemical...Porphyrin-LEGO®: synthesis of a hexafullereno-diporphyrin using porphyrins programmed for [4+2]-cycloaddition - Chemical...
A hexafullereno-diporphyrinoid was obtained in a sequence of cycloaddition steps using porphyrins programmed for [4+2]-cycloaddition reactions and C60-fullerene. Porphyrins & Phthalocyanines
https://pubs.rsc.org/en/content/articlelanding/2012/CC/C2CC31218B
Molecules | Free Full-Text | Unexpected Synthesis of a Bulky Bis-Pocket A3B-Type Meso-Cyano Porphyrin | HTMLMolecules | Free Full-Text | Unexpected Synthesis of a Bulky Bis-Pocket A3B-Type Meso-Cyano Porphyrin | HTML
A one-pot synthesis of bulky bis-pocket A3B-type meso-cyano porphyrin, 5-cyano-10,15,20-tris(2,4,6-triphenylphenyl)porphyrin, has been accomplished via trifluoroacetic acid (TFA) catalyzed condensation of pyrrole and 2,4,6-triphenylbenzaldehyde in an acceptable yield of about 4%. DDQ served as oxidant and the cyanating agent.
http://www.mdpi.com/1420-3049/22/11/1941/htm
Isomeric effect on the properties of tetraplatinated porphyrins showing optimized phototoxicity for photodynamic therapy -...Isomeric effect on the properties of tetraplatinated porphyrins showing optimized phototoxicity for photodynamic therapy -...
The design of new photosensitizers (PS) with improved properties is essential for the development of photodynamic therapy as an alternative therapeutic method. The conjugation of porphyrins, well known PS, with platinum(ii) complexes, potent anticancer agents, may achieve new compounds with synergistic treat
http://pubs.rsc.org/en/content/articlelanding/2017/dt/c7dt01205e
KIT - KIT - Media - Press Releases - Archive Press Releases - Natural Molecule to Boost the Performance of Electrodes for...KIT - KIT - Media - Press Releases - Archive Press Releases - Natural Molecule to Boost the Performance of Electrodes for...
Chlorophyll, blood, and vitamin B12 are all based on the porphyrin molecule. But porphyrin can also be used as an electrode material where it speeds up the charging process of rechargeable batteries. In the Angewandte Chemie International Edition journal, researchers from KIT now present the new material system that could mark the beginning of an era of high-performance energy storage and supercapacitors. Currently, the most widely used battery technology is based on lithium ions. No other rechargeable storage device for electric energy has comparable application properties. Thus, lithium ion batteries are currently indispensable for devices such as laptops, smartphones, or cameras, even though improved properties such as quick-charging would be desirable. Many materials that improve the properties of lithium ion batteries in the lab, however, are no sustainable options because they are rare, expensive, toxic or harmful to the environment. Ideally, high-performance energy storage materials ...
https://www.kit.edu/kit/english/pi_2017_097_natural-molecule-to-boost-the-performance-of-electrodes-for-rechargeable-batteries.php
Sulfobutylether-β-cyclodextrin/5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphine nanoassemblies with sustained antimicrobial...Sulfobutylether-β-cyclodextrin/5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphine nanoassemblies with sustained antimicrobial...
Nowadays, novel less-expensive nanoformulations for in situ-controlled and safe delivery of photosensitisers (PSs) against opportunistic pathogens in body-infections areas need to be developed. Antimicrobial photodynamic therapy (aPDT) is a promising approach to treat bacterial infections that are recalcitrant to antibiotics. In this paper, we propose the design and characterization of a novel nanophototherapeutic based on the trade cyclodextrin CAPTISOL® (sulfobutylether-beta-cyclodextrin, SBE-βCD) and 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphine tetrakis(p-toluenesulfonate) (TMPyP) to fabricate efficient biocompatible systems for aPDT. Spherical nanoassemblies of about 360 nm based on CAPTISOL®/TMPyP supramolecular complexes with 1:1 stoichiometry and apparent equilibrium binding constant (Kb ≅ 1.32 × 105 M−1) were prepared with entrapment efficiency of ≅ 100% by simple mixing in aqueous media and freeze-drying. These systems have been characterized by complementary ...
https://iris.unime.it/handle/11570/3170326
Spectroscopic and computational study of β-ethynylphenylene substituted zinc and free-base porphyrinsSpectroscopic and computational study of β-ethynylphenylene substituted zinc and free-base porphyrins
A series of tetraphenylporphyrins appended at the β-pyrrolic position with an ethynylphenylene- or ethynylpyridine-substituent have been subjected to spectroscopic and density functional theory (DFT) analyses. The mean absolute deviation between corresponding experimental and DFT-derived vibrational spectra is up to 10.2 cm -1, suggesting that the DFT B3LYP/6-31G(d) method provides an accurate model of the β-substituted porphyrin systems. The configuration interactions that give rise to prominent electronic absorptions have been calculated using time-dependant DFT (TD-DFT) and have been rationalized with reference to the energy and topology of DFT calculated molecular orbitals. As the electron withdrawing capacity of the β-substituent increases the LUMO orbital gains appreciable amplitude over the substituent moiety and is stabilised. This represents a departure from the assumptions underpinning the Gouterman four-orbital model, resulting in atypical electronic absorption spectra. This ...
https://scholars.uow.edu.au/display/publication35195
Mossbauer, NMR, Geometric, and Electronic Properties in S=3/2 Iron Por by Yong ZhangMossbauer, NMR, Geometric, and Electronic Properties in S=3/2 Iron Por by Yong Zhang
Iron porphyrins with the intermediate spin S = 3/2 or admixed with S = 5/2 or 1/2 are models for a number of heme protein systems, including cytochromes c. The (57)Fe Mossbauer quadrupole splittings and (1)H and (13)C NMR chemical shifts have been found to be useful probes of their electronic states. We present the results of the first successful quantum chemical calculations of the Mossbauer and NMR properties in various S = 3/2 iron porphyrin complexes, covering four-, five-, and six-coordinate states and three commonly seen porphyrin conformations: planar, ruffled, and saddled. Several interesting correlations among these useful experimental spectroscopic probes and geometric and electronic properties were discovered. These results should facilitate future investigations of related heme proteins and model systems.
https://aquila.usm.edu/fac_pubs/1054/
Boron porphyrinsBoron porphyrins
The Boron porphyrin compounds can be synthesized either from the free base porphyrin or from a lithium porphyrin complex as ... This suggests the porphyrin pocket is more likely to accommodate two boron atoms rather than one. Indeed, each boron porphyrin ... Boron porphyrins are of interest because of the unique geometric environment to which both boron and porphyrin are subjected ... Boron porphyrins are a variety of porphyrin, a common macrocycle used for photosensitization and metal trapping applications, ...
https://en.wikipedia.org/wiki/Boron_porphyrins
PorphyrinPorphyrin
Journal of Porphyrins and Phthalocyanines Handbook of Porphyrin Science Porphynet - an informative site about porphyrins and ... The third porphyrin that is [18]porphyrin-(2.1.1.0), was reported by Callot and Vogel-Sessler. Vogel and coworkers reported ... The first synthetic porphyrin isomer was reported by Emanual Vogel and coworkers in 1986. This isomer [18]porphyrin-(2.0.2.0) ... A porphyrin-related disease: porphyria Porphyrin coordinated to iron: heme A heme-containing group of enzymes: Cytochrome P450 ...
https://en.wikipedia.org/wiki/Porphyrin
Journal of Porphyrins and PhthalocyaninesJournal of Porphyrins and Phthalocyanines
"About Society of Porphyrins and Phthalocyanines (SPP)". spp-jpp.org. "International Conference on Porphyrins and ... The Journal of Porphyrins and Phthalocyanines (JPP) covers the recent research works that happen in the area of porphyrins, ... The Society of Porphyrins & Phthalocyanines (SPP) formed in June 2000, by a group of scientists who are working in the area of ... The Journal of Porphyrins and Phthalocyanines (JPP) was founded in 1997 and is published by World Scientific. It covers " ...
https://en.wikipedia.org/wiki/Journal_of_Porphyrins_and_Phthalocyanines
Phosphorus porphyrinPhosphorus porphyrin
linked several modified porphyrins in a center-to-edge bonding scheme. The chlorines on a P-centered porphyrin are first ... The substituent porphyrins are then refluxed with POCl3 to synthesize the final center-to-edge porphyrin array. The resulting P ... The porphyrin P-N bond distances decrease as the electronegativity of the axial substituents increase. Porphyrins bound to ... Several varieties of the P-centered porphyrin exist. The porphyrin with a core phosphorus (V) ion can be tuned with additional ...
https://en.wikipedia.org/wiki/Phosphorus_porphyrin
Transition metal porphyrin complexesTransition metal porphyrin complexes
... are a family of coordination complexes of the conjugate base of porphyrins. Iron porphyrin ... Metal porphyrin complexes are almost always prepared by direct reaction of a metal halide with the free porphyrin, abbreviated ... In contrast to natural porphyrins, synthetic porphyrin ligands are typically symmetrical (i.e., their dianionic conjugate bases ... The porphyrin dianion is an L2X2 ligand. These syntheses require somewhat forcing conditions, consistent with the tight fit of ...
https://en.wikipedia.org/wiki/Transition_metal_porphyrin_complexes
Handbook of Porphyrin ScienceHandbook of Porphyrin Science
Developments in Supramolecular Chemistry Based on Porphyrins and Related Systems Involvement of Porphyrins and Related Systems ... "The Handbook of Porphyrin Science at World Scientific". Archived from the original on 2010-03-31. Retrieved 2009-08-19. v t e ( ... Published by World Scientific, the Handbook of Porphyrin Science: With Applications to Chemistry, Physics, Materials Science, ... Phthalocyanines and Related Systems Heme Proteins The current work stems from World Scientific's Journal of Porphyrins and ...
https://en.wikipedia.org/wiki/Handbook_of_Porphyrin_Science
Cobalt(II)-porphyrin catalysisCobalt(II)-porphyrin catalysis
... is a process in which a Co(II) porphyrin complex acts as a catalyst, inducing and accelerating a ... A family of unique D2-symmetric chiral porphyrins are effective in a range of stereodefined transformations. Co(II)-porphyrin ... Co(II)-porphyrin catalysts lack vacant cis-coordination sites available (all occupied). This unique metal coordination mode can ... Third, it has been well documented that the physical and chemical properties of a porphyrin complex of a given metal ion can be ...
https://en.wikipedia.org/wiki/Cobalt(II)–porphyrin_catalysis
Trivalent group 14 radicalsTrivalent group 14 radicals
Gouterman, Martin; Schwarz, Frederick; Smith, Paul (1973). "Porphyrins. XXVII. Spin‐orbit coupling and luminescence of Group IV ...
https://en.wikipedia.org/wiki/Trivalent_group_14_radicals
ChromophoreChromophore
Gouterman, Martin (2012). "Optical spectra and electronic structure of porphyrins and related rings". In Dolphin, David (ed.). ... iron in a porphyrin ring) of hemoglobin, or magnesium complexed in a chlorin-type ring in the case of chlorophyll. The highly ... The Porphyrins V3. Physical Chemistry, Part A. Elsevier. pp. 1-165. doi:10.1016/B978-0-12-220103-5.50008-8. ISBN 978-0-323- ...
https://en.wikipedia.org/wiki/Chromophore
Martin GoutermanMartin Gouterman
Porphyrin Chemistry Community[citation needed] Gouterman, Martin (1961-01-01). "Spectra of porphyrins". Journal of Molecular ... The Soret and Q-bands that are visible in porphyrin spectra are the result of transitions from between these four orbitals. ... "Porphyrin UV-Vis , VIPEr". www.ionicviper.org. Retrieved 2021-01-07. "Martin Gouterman - University of Washington Department of ... He is remembered for his seminal work on the optical spectra porphyrins, for which he developed a simple model generally ...
https://en.wikipedia.org/wiki/Martin_Gouterman
Roger GuilardRoger Guilard
"PorphyChem - Porphyrin Chemicals & Engineering". www.porphychem.com. Retrieved April 15, 2019. "PorphyChem - Porphyrin ... Vice President of the Society of Porphyrins and Phthalocyanines (SPP) 1996-2018 - Editorial board of Journal of Porphyrins and ... Robert Burns Woodward Career Award in Porphyrin Chemistry, 6th International Conference on Porphyrins and Phthalocyanines (ICPP ... "Handbook of Porphyrin Science". www.worldscientific.com. Retrieved April 17, 2019. "Series on Chemistry, Energy and the ...
https://en.wikipedia.org/wiki/Roger_Guilard
South Point SchoolSouth Point School
"Society of Porphyrins & Phthalocyanines". www.icpp-spp.org. Retrieved 16 April 2022. "Abhijit Mukherjee". The Times of India. ...
https://en.wikipedia.org/wiki/South_Point_School
Alfred E. TreibsAlfred E. Treibs
These porphyrins resemble chlorophylls. This discovery helped confirm the biological origin of petroleum, which was previously ... Fischer had received the Nobel Prize in Chemistry for elucidating the structures of porphyrins. In the 1930s Treibs discovered ...
https://en.wikipedia.org/wiki/Alfred_E._Treibs
Karl M. KadishKarl M. Kadish
International Conference on Porphyrins and Phthalocyanines. Dr. Kadish is editor-in-chief of the Journal of Porphyrins and ... "Society of Porphyrins & Phthalocyanines". icpp-spp.org. Retrieved August 28, 2018. "1980-1981 Fulbright Scholar Directory" (PDF ... Hans Fischer Lifetime Award in Porphyrin Chemistry, 2012. Prix Franco Américain, 2017 North American editor, Journal of ... Porphyrins and Phthalocyanines, 1997-2001 Editor-in-chief, Journal of Porphyrins and Phthalocyanines, 2001-present Chairman of ...
https://en.wikipedia.org/wiki/Karl_M._Kadish
F. Ann WalkerF. Ann Walker
The Society of Porphyrins and Phthalocyanines awarded her the Eraldo Antonini Award for lifetime achievement award in 2020. " ... "Society of Porphyrins & Phthalocyanines". www.icpp-spp.org. Retrieved 2022-04-13. (CS1 maint: numeric names: authors list, CS1 ... Walker's early work was on porphyrins and their complexation with iron. She was able to obtain structural information about ... Walker, F. Ann; Lo, Man-Wai; Ree, Molly T. (1976). "Electronic effects in transition metal porphyrins. The reactions of ...
https://en.wikipedia.org/wiki/F._Ann_Walker
St. Lawrence High School, KolkataSt. Lawrence High School, Kolkata
"Society of Porphyrins & Phthalocyanines". www.icpp-spp.org. Retrieved 16 April 2022. (Use dmy dates from July 2018, Use Indian ...
https://en.wikipedia.org/wiki/St._Lawrence_High_School,_Kolkata
Alan R. BattersbyAlan R. Battersby
"Robert Burns Woodward Career Award in Porphyrin Chemistry". Society of Porphyrins & Phthalocyanines. Retrieved 1 May 2018. ... 1993). "Biosynthesis of Porphyrins and Related Macrocycles. Part 40. Synthesis of a Spiro-lactam Related to the Proposed Spiro- ... 2000). The Porphyrin Handbook. Vols. 1-25. Academic Press. Milgrom, Lionel R. (1997). The Colours of Life: an Introduction to ... ISBN 978-3-540-17531-5. Baldwin, J.E.; Perlmutter, P. (1984). "Bridged, capped and fenced porphyrins.". In Vögtle, J. F.; Weber ...
https://en.wikipedia.org/wiki/Alan_R._Battersby
PorphinePorphine
Many porphyrins are found in nature with the dominant example being protoporphyrin IX. Many synthetic porphyrins are also known ... Unlike the natural porphyrin ligands, TPP2− is highly symmetrical. Another difference is that its methine centers are occupied ... Common porphyrins Derivatives of protoporphyrin IX are common in nature, the precursor to hemes. Octaethylporphyrin (H2OEP) is ... Unlike the natural porphyrin ligands, OEP2− is highly symmetrical. Tetraphenylporphyrin (H2TPP)is another synthetic analogue of ...
https://en.wikipedia.org/wiki/Porphine
PorphyrinogenPorphyrinogen
Porphyrins differ from porphyrinogens by having the four pyrrole rings linked by methine bridges =CH− instead of methylene ... Porphyrinogens are intermediates in the biosynthesis of porphyrins, cofactors with a porphine core which are found in many ... Lindsey, Jonathan S. (2000). "Synthesis of meso-substituted porphyrins". In Kadish, Karl M.; Smith, Kevin M.; Guilard, Roger ( ... Oxidation turns the central hexahydroporphine core into a porphine core, yielding the desired porphyrin. Under acid catalysis, ...
https://en.wikipedia.org/wiki/Porphyrinogen
Copper phthalocyanineCopper phthalocyanine
Schmidt The Porphyrin Handbook: Applications of Phthalocyanines, e. Karl Kadish, Kevin M. Smith & Roger Guilard Tattoo Inks: ... Journal of Porphyrins and Phthalocyanines. worldscinet.com. 4 (4): 432-437. doi:10.1002/(SICI)1099-1409(200006/07)4:4. 3.0.CO;2 ... which are also formally derived by double deprotonation of porphyrins. CuPc belongs to the D4h point group. It is paramagnetic ... The description is analogous to that for copper porphyrins, ...
https://en.wikipedia.org/wiki/Copper_phthalocyanine
Aminolevulinate transaminaseAminolevulinate transaminase
This enzyme participates in porphyrin and chlorophyll metabolism. It employs one cofactor, pyridoxal phosphate. Gibson KD, ... Matthew M, Neuberger A (1961). "Biosynthesis of porphyrins and chlorophylls". Nature. 192 (4799): 204-208. doi:10.1038/192204a0 ...
https://en.wikipedia.org/wiki/Aminolevulinate_transaminase
Vitamin B12 total synthesisVitamin B12 total synthesis
Craig, G. Wayne (2016). "Total synthesis of vitamin B12 - a fellowship of the ring". Journal of Porphyrins and Phthalocyanines ... This is biogenetically related to porphyrins and chlorophylls, yet differs from them in important respects: the carbon skeleton ... Handbook of Porphyrin Science. Vol. 25. World Scientific Publishing. pp. 265-307. doi:10.1142/9789814397605_0020. ISBN 978-981- ...
https://en.wikipedia.org/wiki/Vitamin_B12_total_synthesis
Technology in Star WarsTechnology in Star Wars
Journal of Porphyrins and Phthalocyanines. 09 (10): 698-705. doi:10.1142/S1088424605000812. Barr, et al. (2017), p. 133 Windham ...
https://en.wikipedia.org/wiki/Technology_in_Star_Wars
Porphyria cutanea tardaPorphyria cutanea tarda
Thunell, S (2000). "Porphyrins, porphyrin metabolism and porphyrias. I. Update". Scandinavian Journal of Clinical and ... "Porphyrin Tests". 7 May 2020. Jackson, A. H.; Ferramola, A. M.; Sancovich, H. A.; Evans, N; Matlin, S. A.; Ryder, D. J.; Smith ... In the absence of iron, which is to be incorporated in the porphyrin formed in the last step of the synthesis, the mRNA of ... Porphyrins interact with iron, absorbing photons to create reactive oxygen species is the mechanism of action causing the itchy ...
https://en.wikipedia.org/wiki/Porphyria_cutanea_tarda
Rothemund reactionRothemund reaction
inspired the work of his student Paul Rothemund to develop a simple one pot synthesis of porphyrins. In 1935 Paul Rothemund ... The aldehyde and pyrrole are heated in this medium to afford modest yields of the meso tetrasubstituted porphyrins [RCC4H2N]4H2 ... A simplified version of Rothemund porphyrin synthesis was described by Alan D. Adler and Frederick R. Longo in 1966. It ... The Rothemund reaction is a condensation/oxidation process that converts four pyrroles and four aldehydes into a porphyrin. It ...
https://en.wikipedia.org/wiki/Rothemund_reaction
PhotooxygenationPhotooxygenation
I. J. MacDonald, and T. J. Dougherty (2001). "Basic principles of photodynamic therapy". Journal of Porphyrins and ...
https://en.wikipedia.org/wiki/Photooxygenation
PhthalocyaninePhthalocyanine
"Society of Porphyrins and Phthalocyanines". spp-jpp.org. Wiki est. (2006-03-21) by Henry Rzepa. Sir Patrick Linstead: ... Both porphyrins and phthalocyanines function as planar tetradentate dianionic ligands that bind metals through four inwardly ... "Journal of Porphyrins and Phthalocyanines". worldscinet.com/jpp/. "ICI Grangemouth discovery" (video). Archived from the ... Phthalocyanines are structurally related to other tetrapyrrole macrocyles including porphyrins and porphyrazines. They feature ...
https://en.wikipedia.org/wiki/Phthalocyanine
TetraphenylporphyrinTetraphenylporphyrin
... the porphyrinogen is subsequently oxidized to deliver the porphyrin. The conjugate base of the porphyrin, TPP2−, belongs to the ... "Synthesis of meso-substituted porphyrins". In Kadish, Karl M.; Smith, Kevin M.; Guilard, Roger (eds.). Porphyrin Handbook. Vol ... is a synthetic heterocyclic compound that resembles naturally occurring porphyrins. Porphyrins are dyes and cofactors found in ... Another synthetic porphyrin, octaethylporphyrin (H2OEP) does have a substitution pattern that is biomimetic. Many derivatives ...
https://en.wikipedia.org/wiki/Tetraphenylporphyrin
PhytanePhytane
Baker, E.W.; Louda, J.W. (1986). "Porphyrins in the geological record". In Johns, R.B. (ed.). Biological Markers in the ...
https://en.wikipedia.org/wiki/Phytane
Abhik GhoshAbhik Ghosh
In 2017, Ghosh and coworkers reported the first example of a stable cis tautomer of a free-base porphyrin in the form of a ... In 2020-2021, Ghosh published two biographical essays on the late Martin Gouterman, a noted porphyrin chemist and one of the ... Ghosh has contributed to many areas of porphyrin-related research. His early contributions include the use of X-ray ... Subsequently, they found additional examples of porphyrin cis tautomers, proving that they can be reliably obtained from ...
https://en.wikipedia.org/wiki/Abhik_Ghosh
Porphyrins urine test: MedlinePlus Medical EncyclopediaPorphyrins urine test: MedlinePlus Medical Encyclopedia
Porphyrins are natural chemicals in the body that help form many important substances in the body. One of these is hemoglobin, ... Normal results vary depending on the type of porphyrin tested. In general, for a 24-hour urine test of total porphyrins, the ... Porphyrins are natural chemicals in the body that help form many important substances in the body. One of these is hemoglobin, ... Your provider will order this test if you have signs of porphyria or other disorders that can cause abnormal urine porphyrins. ...
https://medlineplus.gov/ency/article/003614.htm
Fe-tetra-(2,6-Cl2-phenyl)porphyrin radicalFe-tetra-(2,6-Cl2-phenyl)porphyrin radical
Chemical Injury and Disorders of Porphyrin MetabolismChemical Injury and Disorders of Porphyrin Metabolism
Abnormal levels of porphyrins and/or porphyrin precursors in the urine, stool, blood and/or plasma (although they may be so ... In some acute porphyrias and porphyrinurias, excess porphyrins and/or porphyrin precursors may be evident only during an acute ... porphyrin(s) and/or porphyrin precursors (substances called ALA and PBG which are measured to check the activity of the first ... Disorders of Porphyrin Metabolism, New York: Plenum Medical Book Company.. Scriver CR, AL Beaudet, WS Sly, and D Valle (editors ...
https://www.ei-resource.org/articles/multiple-chemical-sensitivity-articles/chemical-injury-and-disorders-of-porphyrin-metabolism/
British Library EThOS: Supramolecular porphyrin arrays on DNA and SWNT scaffoldsBritish Library EThOS: Supramolecular porphyrin arrays on DNA and SWNT scaffolds
Homo- and hetero-porphyrin single walled carbon nanotube adducts have been prepared with neutral, tetra-anionic and tetra- ... A novel porphyrin modified nucleoside with multiple degrees of freedom about the linking moiety has been synthesised. ... Stable B form duplexes were observed in all cases, with the porphyrin modifications imparting a stabilising effect on the ... Excitonic coupling of the porphyrins is observed; the different monomers incorporated into DNA show different effects in the ...
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.543404
APS -APS March Meeting 2014 - Event - Charge and spin transport in porphyrin-based molecular junctionsAPS -APS March Meeting 2014 - Event - Charge and spin transport in porphyrin-based molecular junctions
Abstract: M2.00003 : Charge and spin transport in porphyrin-based molecular junctions*. 12:03 PM-12:15 PM ... We study weak-bias charge and spin transport behavior of four metal-porphyrin molecules in molecular junctions, using a ...
https://meetings.aps.org/Meeting/MAR14/Session/M2.3
SYNTHESIS OF COVALENTLY-LINKED DIMERIC PORPHYRINS | UBC ChemistrySYNTHESIS OF COVALENTLY-LINKED DIMERIC PORPHYRINS | UBC Chemistry
Department of Chemistry, UBC Faculty of Science. Vancouver Campus. 2036 Main Mall. Vancouver, BC Canada V6T 1Z1. Tel: 604.822.3266. Fax: 604.822.2847. ...
http://www.chem.ubc.ca/synthesis-covalently-linked-dimeric-porphyrins
Broad-band spectroscopy of a vanadyl porphyrin: a model electronuclear spin qudit - Chemical Science (RSC Publishing)Broad-band spectroscopy of a vanadyl porphyrin: a model electronuclear spin qudit - Chemical Science (RSC Publishing)
We explore how to encode more than a qubit in vanadyl porphyrin molecules hosting a S = 1/2 electronic spin coupled to a I = 7/ ... We explore how to encode more than a qubit in vanadyl porphyrin molecules hosting a S = 1/2 electronic spin coupled to a I = 7/ ... Broad-band spectroscopy of a vanadyl porphyrin: a model electronuclear spin qudit I. Gimeno, A. Urtizberea, J. Román-Roche, D. ... Broad-band spectroscopy of a vanadyl porphyrin: a model electronuclear spin qudit† ...
https://pubs.rsc.org/en/content/articlelanding/2021/SC/D1SC00564B
Efficient light-harvesting antenna with a multi-porphyrin cascadeEfficient light-harvesting antenna with a multi-porphyrin cascade
... Efficient light-harvesting antenna with a multi-porphyrin ... Ruthenium porphyrin functionalized single-walled carbon nanotube arrays--a step toward light harvesting antenna and multibit ... Fully Conjugated Porphyrin Glass: Collective Light-Harvesting Antenna for Near-Infrared Fluorescence beyond 1 μm. Acs Omega 3(4 ... Giant porphyrin wheels with large electronic coupling as models of light-harvesting photosynthetic antenna. Chemistry 12(5): ...
https://eurekamag.com/research/052/909/052909574.php
KEGG PATHWAY: Porphyrin metabolism - Homo sapiens (human)KEGG PATHWAY: Porphyrin metabolism - Homo sapiens (human)
Porphyrin metabolism - Homo sapiens (human) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description ... Porphyrins are a group of chemical compounds with the backbone ring structure consisting of four linked pyrrole units. Metal ... complexes of porphyrins, as well as those of corrinoids with the one-carbon shorter ring structure, play important biological ...
https://www.kegg.jp/pathway/hsa00860
porphyrins Archives - preLightsporphyrins Archives - preLights
preLights is a community initiative supported by The Company of Biologists. The Company of Biologists is a not-for-profit publishing organisation dedicated to supporting and inspiring the biological community. The Company publishes five specialist peer-reviewed journals: Development, Journal of Cell Science, Journal of Experimental Biology, Disease Models & Mechanisms and Biology Open. It offers further support to the biological community by facilitating scientific meetings, providing travel grants for researchers and supporting research societies.. In this video our directors tell you more about our activities and why they choose to dedicate their time to the Company.. www.biologists.com. ...
https://prelights.biologists.com/highlight-tags/porphyrins/
BJNANO - Adsorption and self-assembly of porphyrins on ultrathin CoO films on Ir(100)BJNANO - Adsorption and self-assembly of porphyrins on ultrathin CoO films on Ir(100)
Adsorption and self-assembly of porphyrins on ultrathin CoO films on Ir(100) ... Co-DPP (1, PorphyChem SAS, 98% purity, Figure 1a) and 2H-TCNPP (2, Porphyrin Systems, 97% purity, Figure 1b) were evaporated ... Porphyrins represent a versatile class of molecules, the adsorption behavior of which on solid surfaces is of fundamental ... We chose here to investigate two different porphyrins on thin films of cobalt(II) oxide (CoO). Cobalt(II) oxide not only is a ...
https://www.beilstein-journals.org/bjnano/articles/11/134
Porphyrins for dye-sensitised solar cells: New insights into efficiency-determining electron transfer stepsPorphyrins for dye-sensitised solar cells: New insights into efficiency-determining electron transfer steps
Bulky substituents, using a porphyrin dimer instead of a porphyrin monomer, a light soaking treatment of freshly prepared films ... Bulky substituents, using a porphyrin dimer instead of a porphyrin monomer, a light soaking treatment of freshly prepared films ... Porphyrins for dye-sensitised solar cells: New insights into efficiency-determining electron transfer steps Journal Article ... Synthetic porphyrin dyes were amongst the first dyes trialled for sensitisation of inorganic semiconducting oxides. Today, they ...
https://scholars.uow.edu.au/display/publication54494
Transmembrane Nanopores from Porphyrin Supramolecules | CiNii Research
J. Am. Chem. Soc. 130 6314-6315, 2008 ...
https://cir.nii.ac.jp/crid/1010282256927311872?lang=en
Porphyrin Binding to Gun4 protein, Facilitated by a Flexible Loop, Controls Metabolite Flow through the Chlorophyll...Porphyrin Binding to Gun4 protein, Facilitated by a Flexible Loop, Controls Metabolite Flow through the Chlorophyll...
Gun4 is a porphyrin-binding protein known to stimulate in vitro the Mg-chelatase activity but how the Gun4-porphyrin complex ... It revealed that the orientation of 6/7 loop is critical for the binding and the magnesium ion held within the porphyrin is ... Porphyrin Binding to Gun4 protein, Facilitated by a Flexible Loop, Controls Metabolite Flow through the Chlorophyll ... The W192A-Gun4 was further characterized in Mg-chelatase assay showing that tight porphyrin-binding in Gun4 facilitates its ...
https://upcommons.upc.edu/handle/2117/84233
Fiberoptic fluorescence detection of low level porphyrin concentrations in preclinical and clinical studies - Fingerprint ...
Dive into the research topics of Fiberoptic fluorescence detection of low level porphyrin concentrations in preclinical and ... Fiberoptic fluorescence detection of low level porphyrin concentrations in preclinical and clinical studies. ...
https://www.scholars.northwestern.edu/en/publications/fiberoptic-fluorescence-detection-of-low-level-porphyrin-concentr/fingerprints/
Platinum (II) porphyrin-containing thermoresponsive poly(N- isopropylacrylamide) copolymer as fluorescence dual oxygen and...
Zhou, X., Su, F., Tian, Y., Johnson, R. H., & Meldrum, D. (2011). Platinum (II) porphyrin-containing thermoresponsive poly(N- ... Zhou, X, Su, F, Tian, Y, Johnson, RH & Meldrum, D 2011, Platinum (II) porphyrin-containing thermoresponsive poly(N- ... Oxygen response of the platinum (II) porphyrin probes in the polymer followed a two-site Stern-Volmer model, indicating the ... Oxygen response of the platinum (II) porphyrin probes in the polymer followed a two-site Stern-Volmer model, indicating the ...
https://asu.pure.elsevier.com/en/publications/platinum-ii-porphyrin-containing-thermoresponsive-polyn-isopropyl
HKU Scholars Hub: Anticancer Gold(III) Compounds With Porphyrin or N-heterocyclic Carbene LigandsHKU Scholars Hub: Anticancer Gold(III) Compounds With Porphyrin or N-heterocyclic Carbene Ligands
Article: Anticancer Gold(III) Compounds With Porphyrin or N-heterocyclic Carbene Ligands. *Show simple item record ... Coordination ligands containing C and/or N donor atom(s) such as porphyrin, pincer-type cyclometalated and/or N-heterocyclic ... Coordination ligands containing C and/or N donor atom(s) such as porphyrin, pincer-type cyclometalated and/or N-heterocyclic ...
https://hub.hku.hk/handle/10722/302371
Monolayered octopus-porphyrin vesicle: microstructure and oxygen-binding in aqueous medium • Kai Ludwig • Department of Biology...Monolayered octopus-porphyrin vesicle: microstructure and oxygen-binding in aqueous medium • Kai Ludwig • Department of Biology...
Monolayered octopus-porphyrin vesicle: microstructure and oxygen-binding in aqueous medium. E. Tsuchida, T. Komatsu, K. Arai, K ...
https://www.bcp.fu-berlin.de/en/chemie/chemie/forschung/OrgChem/ludwig/veroeffentlichungen/_Publikationen_Inhalt/1995/015/index.html
Nickel(II) Chelatase Variants Directly Evolved from Murine Ferrochelatase: Porphyrin Distortion and Kinetic Mechanism<...Nickel(II) Chelatase Variants Directly Evolved from Murine Ferrochelatase: Porphyrin Distortion and Kinetic Mechanism<...
Using resonance Raman spectroscopy, the structural properties of porphyrins bound to the active site of directly evolved Ni(2+ ... Using resonance Raman spectroscopy, the structural properties of porphyrins bound to the active site of directly evolved Ni(2+ ... Using resonance Raman spectroscopy, the structural properties of porphyrins bound to the active site of directly evolved Ni(2+ ... Using resonance Raman spectroscopy, the structural properties of porphyrins bound to the active site of directly evolved Ni(2+ ...
https://novaresearch.unl.pt/en/publications/nickelii-chelatase-variants-directly-evolved-from-murine-ferroche
Gold nanoparticle-porphyrin self-assembled multistructures for photoelectric conversion<...
Gold nanoparticle-porphyrin self-assembled multistructures for photoelectric conversion. In: Thin Solid Films. 2003 ; Vol. 438- ... Gold nanoparticle-porphyrin self-assembled multistructures for photoelectric conversion. Sunao Yamada, Takashi Tasaki, Tsuyoshi ... Gold nanoparticle-porphyrin self-assembled multistructures for photoelectric conversion. / Yamada, Sunao; Tasaki, Takashi; ... Yamada S, Tasaki T, Akiyama T, Terasaki N, Nitahara S. Gold nanoparticle-porphyrin self-assembled multistructures for ...
https://kyushu-u.pure.elsevier.com/en/publications/gold-nanoparticle-porphyrin-self-assembled-multistructures-for-ph
Methyl 1H-imidazole-2-carboxylate - porphyrin-systemsMethyl 1H-imidazole-2-carboxylate - porphyrin-systems
Porphyrin Systems is a company founded 1999 as a spin-off from the University of Lübeck, Germany. ... Porphyrin Systems Hombrecher e.K.. Papenmoorweg 23. 25469 Halstenbek, Germany. Tel.: +49-4101-6049785. +49-41016049783. Fax: + ...
https://porphyrin-systems.de/produkt/methyl-1h-imidazole-2-carboxylate/
Indium triflate mediated synthesis of meso-substituted porphyrins<...Indium triflate mediated synthesis of meso-substituted porphyrins<...
Smith, BM, Kean, SD, Wyatt, MF & Graham, AE 2008, Indium triflate mediated synthesis of meso-substituted porphyrins, Synlett ... Indium triflate mediated synthesis of meso-substituted porphyrins. Brendan M. Smith*, Suzanna D. Kean, Mark F. Wyatt, Andrew E ... Indium triflate mediated synthesis of meso-substituted porphyrins. / Smith, Brendan M.; Kean, Suzanna D.; Wyatt, Mark F.; ... Catalytic quantities of indium salts are highly efficient promoters for the synthesis of meso-porphyrins in high yields and on ...
https://pure.southwales.ac.uk/cy/publications/indium-triflate-mediated-synthesis-of-meso-substituted-porphyrins
Porphyrin - stk 2022.6.17.1.dev12+g80e138b.d20221209 documentationPorphyrin - stk 2022.6.17.1.dev12+g80e138b.d20221209 documentation
Porphyrin. class Porphyrin(metals, ligands, reaction_factory=None, num_processes=1, optimizer=,stk.molecular.topology_graphs. ...
https://stk.readthedocs.io/en/latest/stk.molecular.topology_graphs.metal_complex.porphyrin.porphyrin.html
Pure and Applied Chemistry, Keyword porphyrins
Porphyrins as spectroscopic sensors for conformational studies of DNA. 2007, Vol. 79, Issue 4, pp. 801-809 [Details + Abstract ... Articles with keyword "porphyrins". François Diederich. Advanced opto-electronics materials by fullerene and acetylene ... Immobilization of 5,10,15,20-tetrakis-(2-fluorophenyl)porphyrin into MCM-41 and NaY: Routes toward photodegradation of ...
http://pac.iupac.org/publications/pac/keywords/porphyrins/
Time-Resolved Resonance Raman Study of the Exciplex Formed Between Excited Cu-Porphyrin and DNA<...Time-Resolved Resonance Raman Study of the Exciplex Formed Between Excited Cu-Porphyrin and DNA<...
Time-Resolved Resonance Raman Study of the Exciplex Formed Between Excited Cu-Porphyrin and DNA. In: Journal of physical ... Time-Resolved Resonance Raman Study of the Exciplex Formed Between Excited Cu-Porphyrin and DNA. / Kruglik, Sergei G.; Mojzes, ... Dive into the research topics of Time-Resolved Resonance Raman Study of the Exciplex Formed Between Excited Cu-Porphyrin and ... Such a rapid exciplex building process implies that it involves porphyrin molecules initially located, in the steady state of ...
https://research.utwente.nl/en/publications/time-resolved-resonance-raman-study-of-the-exciplex-formed-betwee
Photoinduced electron transfer at liquid vertical bar liquid interfaces. Part IV. Orientation and reactivity of zinc tetra(4...Photoinduced electron transfer at liquid vertical bar liquid interfaces. Part IV. Orientation and reactivity of zinc tetra(4...
Orientation and reactivity of zinc tetra(4-carboxyphenyl) porphyrin self-assembled at the water vertical bar 1,2-dichloroethane ... Orientation and reactivity of zinc tetra(4-carboxyphenyl) porphyrin self-assembled at the water vertical bar 1,2-dichloroethane ... Orientation and reactivity of zinc tetra(4-carboxyphenyl) porphyrin self-assembled at the water vertical bar 1,2-dichloroethane ... Orientation and reactivity of zinc tetra(4-carboxyphenyl) porphyrin self-assembled at the water vertical bar 1,2-dichloroethane ...
https://research-information.bris.ac.uk/en/publications/photoinduced-electron-transfer-at-liquid-vertical-bar-liquid-inte
Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter...Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter...
Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter ... Influence of pH and a porphyrin ligand on the stability of a G-quadruplex structure within a duplex segment near the promoter ...
https://www.growkudos.com/publications/10.1016%252Fj.ijbiomac.2020.05.062/reader
Redox switchable NIR dye derived from ruthenium-dioxolene-porphyrin systems - Publications of the IAS FellowsRedox switchable NIR dye derived from ruthenium-dioxolene-porphyrin systems - Publications of the IAS Fellows
Newly synthesised Ru(bp)2(sq)+-derivatives, covalently linked to a porphyrin-core, show very high ε values in the NIR region; ... Redox switchable NIR dye derived from ruthenium-dioxolene-porphyrin systems Chemical Communications (22). pp. 2648-2649. ISSN ...
http://repository.ias.ac.in/78524/
Electrooxidation of porphyrin free bases: Fate of the π-cation radical - Université de Bretagne OccidentaleElectrooxidation of porphyrin free bases: Fate of the π-cation radical - Université de Bretagne Occidentale
Conjunction of electrochemical and spectroscopic data (UV/VIS, EPR and NMR) demonstrates unambiguously that the porphyrin ... the π-cation radicals of porphyrin free bases (H2OEP, H2TPP, H2CdiE) electrogenerated in strictly anhydrous solvents are not ... Electrooxidation of porphyrin free bases: Fate of the π-cation radical C. Inisan J.-Y. Saillard 1 R. Guilard 2 A. Tabard 2 Y. ... Electrooxidation of porphyrin free bases: Fate of the π-cation radical. New Journal of Chemistry, 1998, 22, pp.823--830. ⟨ ...
https://hal.univ-brest.fr/hal-01770755
Introducing Cobalt(II) Porphyrin/Cobalt(III) Corrole Containing TranIntroducing Cobalt(II) Porphyrin/Cobalt(III) Corrole Containing Tran
The compounds of choice were cobalt(II) porphyrin and cobalt(III) corrole-both characterized by a high stability of the ... Introducing Cobalt(II) Porphyrin/Cobalt(III) Corrole Containing Transducers for Improved Potential Reproducibility and ... Thus, carbon nanotubes with the cobalt(II) porphyrin/cobalt(III) corrole system are promising alternatives for existing ...
https://www.researcher-app.com/paper/8425
Water-solubleMoleculesSynthesisTotal porphyrinsExcess porphyrinsLigandsHemeFluorescenceAbstractProperties of porphyrinsSubstituentsMetabolismPhysicsPorphyriaUrine porphyrinsAccumulationDimersSupramolecularTetraMolecularPyrrolePhotoactiveLigandCobaltQuantitativeCatalystsEnzymeExcretionComplexesMonomerUltrafastOxygenCatalyticPorphobilinogenConcentrationsDisordersOrgansCyclicSyntheticSubstrateElectronReactionCatalysisCarbonRedoxOxidationVitroMechanism
Water-soluble11
  • The photoinduced reversible process of exciplex formation and decay between the water-soluble cationic metalloporphyrin 5,10,15,20-tetrakis[4-(N-methylpyridyl)]porphyrin (Cu(T4MPyP)) and calf-thymus DNA has been studied by a picosecond time-resolved resonance Raman (ps-TR3) technique. (utwente.nl)
  • The accumulated isomer I porphyrinogens are spontaneously oxidized to their corresponding porphyrins, which are water-soluble photosensitizers with a reddish hue. (medscape.com)
  • A kind of cationic water-soluble porphyrin containing pyridinium group and a kind of anionic water-soluble porphyrin containing sulfonic group were synthesized efficiently according to the chosen conditions. (sioc-journal.cn)
  • These procedures have the advantages of operation simplicity, high yields, mild conditions, and provide a good method for the synthesis of similar types of water soluble porphyrins at the same time. (sioc-journal.cn)
  • Fluorescence quenching of water-soluble porphyrins. (elsevier.com)
  • Generally, porphyrin catalysts can be grouped into fat-soluble porphyrin catalysts and water-soluble porphyrin catalysts. (bhopalnewspaper.in)
  • In particular, water soluble porphyrins are very interesting since, taking advantage of the self-correcting nature of the supramolecular interactions, defect-free structures can be achieved whose shape, size and photophysical properties are highly sensitive to external stimuli. (unime.it)
  • In this framework, the water soluble tetrakis(4-sulfonatophenyl) porphyrin (TPPS4) provides an iconic example of such behavior, since its diacid form, in particular experimental conditions, is able to self-arrange in well defined J-aggregates supramolecular structures. (unime.it)
  • Harald Gröger and co-workers, University of Erlangen-Nürnberg, Germany, have reported a synthetic, water soluble iron(III) porphyrin that can act as an artificial, biomimetic water producing NAD(P)H oxidase. (chemistryviews.org)
  • They used a iron(III) complex containing the water-soluble, fourfold meso-tetrakis(4-sulfonatophenyl)porphyrin (TSPP) as a ligand. (chemistryviews.org)
  • Porphyrins with high carboxyl group numbers are water soluble and excreted primarily by renal mechanisms. (medscape.com)
Molecules12
  • We study weak-bias charge and spin transport behavior of four metal-porphyrin molecules in molecular junctions, using a combination of break-junction experiments and a self-energy corrected first-principles approach based on density functional theory. (aps.org)
  • We explore how to encode more than a qubit in vanadyl porphyrin molecules hosting a S = 1/2 electronic spin coupled to a I = 7/2 nuclear spin. (rsc.org)
  • 0.1 T, corresponding to resonance frequencies of 9-10 GHz) these properties make vanadyl porphyrin molecules suitable qubit realizations. (rsc.org)
  • Porphyrins represent a versatile class of molecules, the adsorption behavior of which on solid surfaces is of fundamental interest due to a variety of potential applications. (beilstein-journals.org)
  • Due to their variability with respect to functionalization and corresponding potential applications, porphyrins represent a fascinating class of molecules the properties of which at inorganic interfaces still have to be fully understood [1] . (beilstein-journals.org)
  • The molecules employed in this study, Co-5,15-diphenylporphyrin (Co-DPP) and 2 H -tetrakis( p -cyanophenyl)porphyrin (2H-TCNPP), are representatives with which this important hierarchy of interaction energies may be studied. (beilstein-journals.org)
  • Porphyrin molecules offer immense potential as the light harvesting component of dye-sensitised nanocrystalline TiO2 solar cells. (edu.au)
  • Charge recombination between the acceptor species in the redox containing electrolyte and injected electrons is shown to be an important limitation of most porphyrin-sensitised solar cells, accelerated by the presence of porphyrin molecules at the TiO2-electrolyte interface. (edu.au)
  • Such a rapid exciplex building process implies that it involves porphyrin molecules initially located, in the steady state of this interaction, at AT sites of the nucleic acids. (utwente.nl)
  • The photoactive nature of porphyrin molecules results in the bright pink fluorescence of these pigments in urine, teeth, and bones under Wood light illumination. (medscape.com)
  • Graetzel's team found that a zinc-bearing compound, part of a class of molecules known as porphyrins, such as chlorophyll or the iron-bearing heme in hemoglobin that makes blood red, did the job of absorbing sunlight even better, however. (innovationtoronto.com)
  • DPY-0801, CAS#68500-80-1, is a useful intermediate for chemical synthesis of a number of biologically important molecules, including porphyrins, bile pigments, photosensitizers, anticancer drugs. (medkoo.com)
Synthesis5
  • Catalytic quantities of indium salts are highly efficient promoters for the synthesis of meso-porphyrins in high yields and on a large scale under mild reaction conditions. (southwales.ac.uk)
  • Erythropoietic porphyria (EP) is a rare inborn error of porphyrin-heme synthesis inherited that is as an autosomal recessive trait. (medscape.com)
  • During the synthesis process, 5,10,15,20-tetra(pyridin-4-yl)porphyrin and 5,10,15,20-tetra-phenol porphyrin were chosen as the precursors, while triethylene glycol monomethyl ether and manganese were introduced on porphyrin as the functional group. (sioc-journal.cn)
  • Vitamin B12 is a porphyrin-like molecule containing cobalt (termed cobalamin) which is necessary for the transformation of methyltetrahydrofolate to tetrahydrofolate for DNA synthesis. (who.int)
  • Porphyria cutanea tarda is a disease caused by a chronic disturbance in hepatic porphyrin synthesis, resulting in accumulation of photosensitive porphyrins in the skin and other organs. (cyberderm.net)
Total porphyrins5
  • In general, for a 24-hour urine test of total porphyrins, the range is about 20 to 120 µg/L (25 to 144 nmol/L). (medlineplus.gov)
  • What are Total Porphyrins? (healthmatters.io)
  • 1 Comment on What are Total Porphyrins? (healthmatters.io)
  • In general, for a 24-hour urine test of total porphyrins, the range is about 23.3 - 132.4 mcg/g creat. (healthmatters.io)
  • Urine samples from 39 controls, 7 patients with porphyrias and 20 patients with liver impairment were quantitated for total porphyrins, followed by a comparison of the two qualitative tests. (who.int)
Excess porphyrins3
  • When the heme-making pathway is disrupted in this way, the excess porphyrins which are no longer metabolized start to accumulate in certain body organs where they can have toxic effects. (ei-resource.org)
  • The interaction of excess porphyrins in the skin and light radiation causes photoxidative damage of biomolecular targets that is manifested as mechanical fragility and blistering that may result in severe scarring. (medscape.com)
  • Hepatic tumors producing excess porphyrins are rare causes of porphyria cutanea tarda-like disorders. (medscape.com)
Ligands3
  • Coordination ligands containing C and/or N donor atom(s) such as porphyrin, pincer-type cyclometalated and/or N-heterocyclic carbene (NHC) can be employed to stabilize gold(III) ion for the preparation of anticancer active compounds. (hku.hk)
  • Tetraazaporphyrin is used as a primitive fragment to examine theoretically the electron donor-acceptor properties of a variety of highly conjugated planar ligands of the porphyrin and phthalocyanine type. (elsevier.com)
  • Analogous to porphyrins, poly(dipyrromethene) ligands can endow their metal complexes with intense absorption bands in the visible region. (ubc.ca)
Heme3
  • Since most heme is made in the bone marrow, these 'disorders of porphyrin metabolism' are usually found there or in the liver. (ei-resource.org)
  • Porphyrins and heme components are extracted from whole blood into a 4:1 mixture of ethyl acetate-acetic acid. (cdc.gov)
  • When hepatic UROD activity falls below the critical threshold, porphyrin by-products of the heme biosynthetic pathway with 4-8 carboxyl group substituents are overproduced. (medscape.com)
Fluorescence3
  • Steady-state and time-resolved fluorescence studies showed that singlet-excited-state energy transfer occurs from the peripheral porphyrins to the central porphyrin with >90% efficiency and rate constants on the order of 10(10) s(-1). (eurekamag.com)
  • A time-gated fluorescence-imaging technique was applied to study the distribution of sensitizer in porphyrin-treated tumour-bearing mice. (unimi.it)
  • Study of porphyrin fluorescence in tissue samples of tumour-bearing mice / R. Cubeddu, G. Canti, P. Taroni, G. Valentini. (unimi.it)
Abstract1
  • abstract = "Multistructure assemblies consisting of porphyrin and gold nanoparticles have been fabricated on an indium-tin-oxide electrode by using alternate gold-sulfur self-assembling. (elsevier.com)
Properties of porphyrins1
  • Using resonance Raman spectroscopy, the structural properties of porphyrins bound to the active site of directly evolved Ni(2+)-chelatase variants are now examined with regard to the mode and extent of porphyrin deformation and related to the catalytic properties of the enzymes. (unl.pt)
Substituents1
  • Bulky substituents, using a porphyrin dimer instead of a porphyrin monomer, a light soaking treatment of freshly prepared films and co-sensitization of TiO2 with multiple dyes are shown to be successful strategies to improve electron lifetime. (edu.au)
Metabolism3
  • The term porphyrinuria (pour-'frin-ur-E-a) is used to categorize disorders of porphyrin metabolism and excretion that are acquired from diseases, drugs or chemicals with or without inherited enzyme abnormalities. (ei-resource.org)
  • The broader term 'porphyrinopathy' is used here to refer to any disorder of porphyrin metabolism, inherited or acquired. (ei-resource.org)
  • What kinds of symptoms are seen in Disorders of Porphyrin Metabolism? (ei-resource.org)
Physics1
  • The broad goal of the Society of Porphyrins and Phthalocyanines (SPP) is to serve the interests of scientists working in any area of porphyrins, phthalocyanine, and related macrocycles, independent of their scientific discipline, be it chemistry, physics, biology, biochemistry or material science. (spp-jpp.org)
Porphyria5
  • Your provider will order this test if you have signs of porphyria or other disorders that can cause abnormal urine porphyrins. (medlineplus.gov)
  • Porphyrin by-products of the pathway exit the hepatocytes, are distributed throughout the body in blood plasma, mediate photooxidative chemical reactions causing skin lesions, and yield the abnormal excretory porphyrin profiles that characterize porphyria cutanea tarda. (medscape.com)
  • Porphyria is a disorder that results from a build-up of natural chemical known as porphyrin in human body. (drvikram.com)
  • Nonspecific (1-2 times reference range) elevation of urine porphyrins, especially coproporphyrins, is common and is not specific for porphyria. (medscape.com)
  • In cases in which the porphobilinogen, 5-aminolevulinate, and porphyrin analyses are within reference intervals and in which there is high suspicion of a previous illness caused by an acute porphyria, mutation analysis of the HMBS gene followed by porphobilinogen deaminase assay is an effective strategy for diagnosis or exclusion of AIP. (medscape.com)
Urine porphyrins1
  • Elevation of urine porphyrins, especially coporphobilinogen, is observed. (medscape.com)
Accumulation3
  • Finally, we introduced the W192A mutation into Synechocystis 6803 cells and show that the Gun4-porphyrin complex is important for the accumulation of ChlH and for channeling metabolites into the chlorophyll biosynthetic pathway. (upc.edu)
  • The inheritance of 2 mutant alleles for the gene encoding the enzyme uroporphyrinogen III synthase leads to accumulation of porphyrins of the isomer I type that are biologically useless but cause cutaneous photosensitivity characterized by blisters, erosions, and scarring of light-exposed skin. (medscape.com)
  • Porphyrin accumulation in humans with common dysfunctional variants of ABCG2, a porphyrin transporter: potential association with acquired photosensitivity. (cdc.gov)
Dimers1
  • Finally, new developments unique to porphyrin dye-sensitised solar cells, including performance enhancements from a light exposure treatment of a zinc porphyrin dye, a significant performance improvement observed after co-sensitisation of TiO2 with free-base and zinc porphyrin dyes and the use of porphyrin dimers with increased light harvesting in thin-film TiO2 solar cells are described. (edu.au)
Supramolecular1
  • A variety of supramolecular porphyrin arrays on DNA or single walled carbon nanotube scaffolds are presented herein. (bl.uk)
Tetra6
  • Homo- and hetero-porphyrin single walled carbon nanotube adducts have been prepared with neutral, tetra-anionic and tetra-cationic porphyrins. (bl.uk)
  • Interfacial properties of zinc tetra(3-carboxyphenyl) porphyrin (ZnTPPC) specifically adsorbed at the water/1,2-dichlorocthane (DCE) junction were elucidated from the photoelectrochemical behavior under linearly polarized light. (bris.ac.uk)
  • strains using tetra-cationic platinum(II) porphyrins. (bvsalud.org)
  • This manuscript presents the first report on antimicrobial photo-inactivation in vitro using tetra -cationic porphyrins with peripheral platinum (II) bipyridyl complexes against Gram-positive bacteria . (bvsalud.org)
  • Two isomeric tetra -cationic porphyrins (3TPyP and 4TPyP) were tested against clinically important bacterial species. (bvsalud.org)
  • Thus, tetra -cationic porphyrins containing platinum (II) complexes are promising agents for microbial photo-inactivation as an alternative therapy against infections . (bvsalud.org)
Molecular5
  • Functionalization of porphyrins may introduce new properties of the molecular adlayer, for example, by introducing elements that allow for strong anchoring [8,10-13] . (beilstein-journals.org)
  • In this feature article we highlight our recent discoveries of the influence of porphyrin molecule structure on efficiency determining electron transfer kinetics and device performance by systematically changing the molecular structure and observing electron injection and recombination kinetics using time-resolved optical and electrical probes. (edu.au)
  • Despite our observation of ultrafast charge injection for all porphyrin dyes studied by transient absorption spectroscopy, the injection yield estimated using an internal standard remains below 100% and depends strongly on the molecular structure. (edu.au)
  • This recombination reaction is strongly dependent on the porphyrin molecular structure. (edu.au)
  • Porphyrin and its derivatives are special molecular scaffolds that have relevant activities and cost-competitive transformations in multiple fields. (bhopalnewspaper.in)
Pyrrole3
  • Porphyrins are a group of chemical compounds with the backbone ring structure consisting of four linked pyrrole units. (kegg.jp)
  • The catalytic mechanism of ferrochelatase has been proposed to involve the stabilization of a nonplanar porphyrin to present the pyrrole nitrogens to the metal ion substrate. (unl.pt)
  • Porphyrins with four acetic acid and four propionic acid side chains attached to the pyrrole rings. (bvsalud.org)
Photoactive1
  • these excess substrates then undergo iron-facilitated spontaneous oxidization to photoactive porphyrins. (medscape.com)
Ligand1
  • The higher reactivity of iron(II) porphyrins toward such π acceptor species, compared to iron(II) phthalocyanine, is attributed to the longer Me-N bond length in the porphyrins, which leads to less metal to ligand back-bonding and thus to more electron charge at the metal center. (elsevier.com)
Cobalt5
  • We investigate here the molecule-molecule and molecule-substrate interaction of Co-5,15-diphenylporphyrin (Co-DPP) and 2 H -tetrakis( p -cyanophenyl)porphyrin (2H-TCNP) on one bilayer (1BL) and two bilayer (2BL) thick cobalt oxide films on Ir(100) by scanning tunneling microscopy (STM) and density functional theory (DFT). (beilstein-journals.org)
  • We chose here to investigate two different porphyrins on thin films of cobalt(II) oxide (CoO). (beilstein-journals.org)
  • The compounds of choice were cobalt(II) porphyrin and cobalt(III) corrole-both characterized by a high stability of the coordinated metal ions in their respective redox states and electrical neutrality, as well as relatively high lipophilicity. (researcher-app.com)
  • Thus, carbon nanotubes with the cobalt(II) porphyrin/cobalt(III) corrole system are promising alternatives for existing transducer systems for potentiometric sensors. (researcher-app.com)
  • When coordinated with metals such as iron, cobalt, or aluminum, the porphyrin or porphyrin derivative is able to catalyze the copolymerization of carbon dioxide and epoxy compounds by cocatalyst. (bhopalnewspaper.in)
Quantitative2
  • In contrast to metalloporphyrins with non-electroactive metal centres, the π-cation radicals of porphyrin free bases (H2OEP, H2TPP, H2CdiE) electrogenerated in strictly anhydrous solvents are not stable and give rise to a quantitative chemical reaction. (univ-brest.fr)
  • Objective: To evaluate the efficiency of two urinary porphyrins screening tests: routine fluorescent detection and semi quantitative spectrophotometric scanning. (who.int)
Catalysts3
  • Most recently, the chemical supplier, Alfa Chemistry, announced the decision to introduce porphyrins into its already diversified offering of catalysts. (bhopalnewspaper.in)
  • During the last century, the catalytic property of porphyrins has been extensively explored, allowing porphyrins to win a position in the family of catalysts. (bhopalnewspaper.in)
  • For more information about Alfa Chemistry Catalysts' porphyrin offerings, please visit https://www.alfachemic.com/catalysts/products/porphyrins-catalysts.html or email us directly. (bhopalnewspaper.in)
Enzyme1
  • Previously, we hypothesized that the ferrochelatase-induced nonplanar distortions of the porphyrin substrate impose selectivity for the divalent metal ion incorporated into the porphyrin ring and facilitate the release of the metalated porphyrin through its reduced affinity for the enzyme. (unl.pt)
Excretion1
  • Three patients who had been previously treated with EDTA showed normal fecal and urine porphyrin excretion and significantly less hyperpigmentation and scarring than most untreated patients. (cdc.gov)
Complexes1
  • Metal complexes of porphyrins, as well as those of corrinoids with the one-carbon shorter ring structure, play important biological roles. (kegg.jp)
Monomer1
  • Stable B form duplexes were observed in all cases, with the porphyrin modifications imparting a stabilising effect on the duplexes, the degree of stabilisation the novel porphryin monomer provides is of a similar level to that of the rigid linked monomer. (bl.uk)
Ultrafast1
  • 1992, 96, 6450): (i) although the binding mode of the porphyrin actually depends on the base sequence, there is no preferential binding of Cu(T4MPyP) to the various sites of DNA, and (ii) there is no photoinduced ultrafast porphyrin translocation from GC to AT sites of DNA. (utwente.nl)
Oxygen7
  • A random copolymer, poly(NIPAAm-co-PtPorphyrin), consisting of N-isopropylacrylamide (NIPAAm) and platinum (II) porphyrin units, behaves as an optical dual sensor for oxygen and temperature. (elsevier.com)
  • The dual sensor is designed by incorporating an oxygen-sensitive platinum (II) porphyrin (M1) into a temperature-sensitive polymer (PNIPAAm). (elsevier.com)
  • Oxygen response of the platinum (II) porphyrin probes in the polymer followed a two-site Stern-Volmer model, indicating the nonuniform distribution of the probes. (elsevier.com)
  • The assemblies exhibit clear photocurrent responses ascribing to photoexcitation of porphyrin in the presence of oxygen as a sacrificial electron acceptor. (elsevier.com)
  • Porphyrins are natural chemicals in the body that help form many important substances in the body such as hemoglobin , the protein in red blood cells that carries oxygen in the blood. (healthmatters.io)
  • The minimal inhibitory concentration of the porphyrin increased in the presence of reactive oxygen species scavengers, indicating that singlet oxygen and radical species likely participated in the photo-oxidation mechanism. (bvsalud.org)
  • Porphyrins are essential for the function of haemoglobin, a protein in the red blood cells that links to porphyrin, binds iron, and carries oxygen to the organs and tissues. (drvikram.com)
Catalytic1
  • The catalytic activity of the iron(III) C2 chiral porphyrin Fe(2)(OMe) in alkene cyclopropanation is herein reported. (unipv.it)
Porphobilinogen1
  • these tests detect porphobilinogen at levels greater than 6 mg/L. A common error is to order a urine porphyrin screen. (medscape.com)
Concentrations3
  • Nevertheless, the images show that porphyrins localize with different concentrations in all the examined tissues except the brain. (unimi.it)
  • Porphyrins are normally present at low concentrations in blood and other body fluids, such as urine. (healthmatters.io)
  • The porphyrin 3-PtTPyP was the most efficient PS against the bacteria tested, inhibiting bacterial growth in just 15 min and 30 min at low concentrations (3.75 and 0.45 µM). (bvsalud.org)
Disorders2
  • These porphyrin disorders usually are found in the liver and are called coprophyrinuria when limited to coproporphyrins. (ei-resource.org)
  • Porphyrin tests are used to help diagnose and monitor a group of disorders called porphyrias. (healthmatters.io)
Organs1
  • These porphyrins are reddish pigments that accumulate in the liver and are disseminated in plasma to other organs. (medscape.com)
Cyclic1
  • Cyclic voltammetry has shown that the inclusion of multiple porphyrin modifications increase the electron transfer rate to the anthraquinone redox marker. (bl.uk)
Synthetic2
  • Synthetic porphyrin dyes were amongst the first dyes trialled for sensitisation of inorganic semiconducting oxides. (edu.au)
  • Hybrid porphyrin tapes 3 and 4, consisting of a mixture of 3,5-di-tert-butylphenyl-substituted donor-type Zn II -porphyrins and pentafluorophenyl-substituted acceptor-type Zn II -porphyrins, were prepared by a synthetic route involving cross-condensation reaction of a Ni II -porphyrinyldipyrromethane and pentafluorophenyldipyrromethane with pentafluorobenzaldehyde followed by appropriate demetalation, remetalation, and oxidative ring-closure reaction. (elsevier.com)
Substrate1
  • The Ni(2+)-chelatase variants (S143T, F323L, and S143T/F323L), which were directly evolved to exhibit an enhanced Ni(2+)-chelatase activity over that of the parent wild-type ferrochelatase, induced a weaker saddling deformation of the porphyrin substrate. (unl.pt)
Electron2
  • The electron transfer in the free bases of these chlorin- and bacteriochlorin-quinones ist about five times faster than in the corresponding porphyrin-quinone. (fu-berlin.de)
  • Cytochromes (electron-transporting proteins) with a tetrapyrrolic chelate of iron as a prosthetic group in which the degree of conjugation of double bonds is less than in porphyrin. (bvsalud.org)
Reaction2
  • Conjunction of electrochemical and spectroscopic data (UV/VIS, EPR and NMR) demonstrates unambiguously that the porphyrin skeleton is not modified during the chemical reaction. (univ-brest.fr)
  • The study of the cyclopropanation reaction revealed that the porphyrin skeleton is composed of two 'totem' parts which were independently responsible for the observed enantio- and diastereoselectivities. (unipv.it)
Catalysis1
  • Porphyrin structure features can be controlled in order to introduce and tune, in the self-assembled material, functional properties for a wide range of application spanning from catalysis, to sensors, optoelectronics or drug delivery. (unime.it)
Carbon1
  • Highly ordered mesoporous carbon/iron porphyrin nanoreactor for the electrochemical reduction of CO2. (edu.au)
Redox3
  • Das, Amitava (2002) Redox switchable NIR dye derived from ruthenium-dioxolene-porphyrin systems Chemical Communications (22). (ias.ac.in)
  • Singly meso-meso-linked hybrid porphyrin arrays 12 and 14 exhibit redox potentials that roughly correspond to each constituent porphyrin segments, while the redox potentials of the hybrid porphyrin tapes 3 and 4 are positively shifted as a whole. (elsevier.com)
  • PCN-222(Fe) is built from redox-active Fe-porphyrin-derived linkers and reported to be active for electrochemical sensing applications [ 50 ] . (ccspublishing.org.cn)
Oxidation2
  • Durch Reduktion eines Porphyrin-Hydrochinons mit Diimin und anschließende selektive Oxidation des Hydrochinon-Abschnitts mit p-Benzochinon erhält man zwei Chlorin-Chinon- Isomere, verknüpft über die Chlorin-Positionen 5 und 10, sowie ein Bacteriochlorin-Chinon. (fu-berlin.de)
  • Two meso-substituted chlorin-quinones, linked via the chlorin-positions 5 and 10, and a bacteriochlorin-quinone were obtained by reduction of a porphyrin- hydroquinone with diimine, followed by selective oxidation of the hydroquinone moiety with p--benzoquinone. (fu-berlin.de)
Vitro1
  • Gun4 is a porphyrin-binding protein known to stimulate in vitro the Mg-chelatase activity but how the Gun4-porphyrin complex acts in the cell was unknown. (upc.edu)
Mechanism1
  • To address this issue we first performed simulations to determine the porphyrin-docking mechanism to the cyanobacterial Gun4 structure. (upc.edu)
(emedicine.medscape.com)
Porphyrin Products - Gentaur Portugal Laboratories
Porphyrin Products - Gentaur Portugal Laboratories (gentaur.pt)
Parasitärer Wurm - Wikipedia
Parasitärer Wurm - Wikipedia (de.wikipedia.org)
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Porphyrins urine test: MedlinePlus Medical Encyclopedia
Porphyrins urine test: MedlinePlus Medical Encyclopedia (medlineplus.gov)
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Porphyria | MedlinePlus (medlineplus.gov)
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Porphyria: MedlinePlus Genetics (medlineplus.gov)
The native architecture of a photosynthetic membrane | Nature
The native architecture of a photosynthetic membrane | Nature (nature.com)
FECH gene: MedlinePlus Genetics
FECH gene: MedlinePlus Genetics (medlineplus.gov)
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Porphyria - NIDDK (niddk.nih.gov)
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Acute Intermittent Porphyria Workup: Laboratory Studies, Imaging Studies, Other Tests (medscape.com)
(emedicine.medscape.com)
(emedicine.medscape.com)
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