Polysorbates
Encyclopedias as Topic
Spiroplasmataceae
Mycoplasmataceae
Bacteriophage inactivation at the air-water-solid interface in dynamic batch systems. (1/492)
Bacteriophages have been widely used as surrogates for human enteric viruses in many studies on virus transport and fate. In this investigation, the fates of three bacteriophages, MS2, R17, and phiX174, were studied in a series of dynamic batch experiments. Both MS2 and R17 readily underwent inactivation in batch experiments where solutions of each phage were percolated through tubes packed with varying ratios of glass and Teflon beads. MS2 and R17 inactivation was the result of exposure to destructive forces at the dynamic air-water-solid interface. phiX174, however, did not undergo inactivation in similar studies, suggesting that this phage does not accumulate at air-water interfaces or is not affected by interfacial forces in the same manner. Other batch experiments showed that MS2 and R17 were increasingly inactivated during mixing in polypropylene tubes as the ionic strength of the solution was raised (phiX174 was not affected). By the addition of Tween 80 to suspensions of MS2 and R17, phage inactivation was prevented. Our data suggest that viral inactivation in simple dynamic batch experiments is dependent upon (i) the presence of a dynamic air-water-solid interface (where the solid is a hydrophobic surface), (ii) the ionic strength of the solution, (iii) the concentration of surface active compounds in the solution, and (iv) the type of virus used. (+info)Comparison of immunity generated by nucleic acid-, MF59-, and ISCOM-formulated human immunodeficiency virus type 1 vaccines in Rhesus macaques: evidence for viral clearance. (2/492)
The kinetics of T-helper immune responses generated in 16 mature outbred rhesus monkeys (Macaca mulatta) within a 10-month period by three different human immunodeficiency virus type 1 (HIV-1) vaccine strategies were compared. Immune responses to monomeric recombinant gp120SF2 (rgp120) when the protein was expressed in vivo by DNA immunization or when it was delivered as a subunit protein vaccine formulated either with the MF59 adjuvant or by incorporation into immune-stimulating complexes (ISCOMs) were compared. Virus-neutralizing antibodies (NA) against HIV-1SF2 reached similar titers in the two rgp120SF2 protein-immunized groups, but the responses showed different kinetics, while NA were delayed and their levels were low in the DNA-immunized animals. Antigen-specific gamma interferon (IFN-gamma) T-helper (type 1-like) responses were detected in the DNA-immunized group, but only after the fourth immunization, and the rgp120/MF59 group generated both IFN-gamma and interleukin-4 (IL-4) (type 2-like) responses that appeared after the third immunization. In contrast, rgp120/ISCOM-immunized animals rapidly developed marked IL-2, IFN-gamma (type 1-like), and IL-4 responses that peaked after the second immunization. To determine which type of immune responses correlated with protection from infection, all animals were challenged intravenously with 50 50% infective doses of a rhesus cell-propagated, in vivo-titrated stock of a chimeric simian immunodeficiency virus-HIVSF13 construct. Protection was observed in the two groups receiving the rgp120 subunit vaccines. Half of the animals in the ISCOM group were completely protected from infection. In other subunit vaccinees there was evidence by multiple assays that virus detected at 2 weeks postchallenge was effectively cleared. Early induction of potent type 1- as well as type 2-like T-helper responses induced the most-effective immunity. (+info)Purification and characterization from rat kidney membranes of a novel platelet-activating factor (PAF)-dependent transacetylase that catalyzes the hydrolysis of PAF, formation of PAF analogs, and C2-ceramide. (3/492)
We have previously identified two enzyme activities that transfer the acetyl group from platelet-activating factor (PAF) in a CoA-independent manner to lysoplasmalogen or sphingosine in HL-60 cells, endothelial cells, and a variety of rat tissues. These were termed as PAF:lysoplasmalogen (lysophospholipid) transacetylase and PAF:sphingosine transacetylase, respectively. In the present study, we have solubilized and purified this PAF-dependent transacetylase 13,700-fold from rat kidney membranes (mitochondrial plus microsomal membranes) based on the PAF:lysoplasmalogen transacetylase activity. The mitochondria and microsomes were prepared and washed three times, then solubilized with 0.04% Tween 20 at a detergent/protein (w/w) ratio of 0.1. The solubilized fractions from mitochondria and microsomes were combined and subjected to sequential column chromatographies on DEAE-Sepharose, hydroxyapatite, phenyl-Sepharose, and chromatofocusing. The enzyme was further purified by native-polyacrylamide gel electrophoresis (PAGE) and affinity gel matrix in which the competitive inhibitor of the enzyme, 1-O-hexadecyl-2-N-methylcarbamyl-sn-glycero-3-phosphoethanolamine was covalently attached to the CH-Sepharose. On SDS-PAGE, the purified enzyme showed a single homogeneous band with an apparent molecular mass of 40 kDa. The purified enzyme catalyzed transacetylation of the acetyl group not only from PAF to lysoplasmalogen forming plasmalogen analogs of PAF, but also to sphingosine producing N-acetylsphingosine (C2-ceramide). In addition, this enzyme acted as a PAF-acetylhydrolase in the absence of lipid acceptor molecules. These results suggest that PAF-dependent transacetylase is an enzyme that modifies the cellular functions of PAF through generation of other diverse lipid mediators. (+info)Enzymatic properties of vesicle-reconstituted human cytochrome P450SCC (CYP11A1) differences in functioning of the mitochondrial electron-transfer chain using human and bovine adrenodoxin and activation by cardiolipin. (4/492)
The recently reported heterologous expression and purification of both human cytochrome P450SCC and adrenodoxin [Woods, S.T., Sadleir, J., Downs, T., Triantopoulos, T., Haedlam, M.J. & Tuckey, R.C. (1998) Arch. Biochem. Biophys. 353, 109-115] has enabled us to perform studies with the membrane-reconstituted human enzymes to better understand the side-chain cleavage reaction in humans. Human P450SCC was successfully reconstituted into dioleoylphosphatidylcholine vesicles with and without cardiolipin and its enzymatic properties characterized in the membrane-bound state. Enhancement of the P450SCC activity and significant activation by cardiolipin were observed when human adrenodoxin instead of bovine adrenodoxin was used as electron donor. In the absence of cardiolipin, Km for cholesterol was decreased twice in the case of human adrenodoxin indicating enhanced cholesterol binding. On the other hand, in the presence of cardiolipin in the membrane both Km and V for cholesterol were decreased with human adrenodoxin as electron donor. Kinetic analysis of the interaction between human P450SCC and its redox partners provided evidence for enhanced binding of the human electron donor to human P450SCC indicated by both an increased V and decreased Kd for human adrenodoxin compared with the values with bovine adrenodoxin. Because no similar effects were observed in Tween 20 micelles, these results suggest that the phospholipid membrane may play an important role in the interaction of human adrenodoxin with human P450SCC. (+info)Virus passage through track-etch membranes modified by salinity and a nonionic surfactant. (5/492)
Why do viruses sometimes not pass through larger pores in track-etch filters? Increasing the salinity (0.8 to 160 mM Na+) decreased phiX174 and PRD1 passage through track-etch polycarbonate membranes (sodium dodecyl sulfate coated but not polyvinylpyrrolidone coated) and PRD1 passage through polyester membranes. Undiminished passage when 0.1% Tween 80 was added implied that nonionic virus adsorption occurred and indicated that high levels of salinity decreased virus passage by decreasing electrostatic repulsion that prevented adsorption. (+info)Rapid esterase-sensitive breakdown of polysorbate 80 and its impact on the plasma pharmacokinetics of docetaxel and metabolites in mice. (6/492)
We have developed and validated an analytical methodology for the quantification of docetaxel and its four major human oxidation metabolites in mouse plasma. We have used this procedure to study the pharmacokinetics and metabolism of docetaxel in female FVB mice, receiving 2.5, 10, or 33 mg/kg of docetaxel by i.v. injection. We have also studied the pharmacokinetics of polysorbate 80, because it was shown previously that the vehicle substance Cremophor EL, which is used in the formulation of paclitaxel, exerts a profound effect on the pharmacokinetics of this compound. Linear pharmacokinetics of docetaxel was observed at dose levels between 2.5 and 10 mg/kg, where plasma levels corresponded to those in patients receiving the maximum tolerated dose. At the highest dose level of 33 mg/kg, a deviation from the linear kinetics was observed. Compared with humans, mice could tolerate much higher plasma levels, suggesting that the toxic side effects are related to a certain plasma threshold concentration instead of area under the curve or Cmax. At the highest dose level, three docetaxel metabolites could be detected in the plasma samples of mice for up to 4 h after drug administration. The hydroxy metabolite of the tert-butoxy group (metabolite II) was the major metabolite, followed by the two epimeric hydroxyoxazolone-type compounds (metabolites I and III). A fourth putative metabolite (e.g., the cyclic oxazolidinedione derivative) was not detected. Because of rapid degradation of polysorbate 80 by esterases in plasma, the concentration of this vehicle substance declined very rapidly. Consequently, this substance was not able to interfere in the disposition of docetaxel. (+info)A novel surfactant nanoemulsion with broad-spectrum sporicidal activity against Bacillus species. (7/492)
Two nontoxic, antimicrobial nanoemulsions, BCTP and BCTP 401, have been developed. These emulsions are composed of detergents and oils in 80% water. BCTP diluted up to 1:1000 inactivated>90% of Bacillus anthracis spores in 4 h and was also sporicidal against three other Bacillus species. This sporicidal activity is due to disruption of the spore coat after initiation of germination without complete outgrowth. BCTP 401 diluted 1:1000 had greater activity than BCTP against Bacillus spores and had an onset of action of <30 min. Mixing BCTP or BCTP 401 with Bacillus cereus prior to subcutaneous injection in mice reduced the resulting skin lesion by 99%. Wound irrigation with BCTP 1 h after spore inoculation yielded a 98% reduction in skin lesion size, and mortality was reduced 3-fold. These nanoemulsion formulas are stable, easily dispersed, nonirritant, and nontoxic compared with other available sporicidal agents. (+info)Accumulation of rifampicin by Mycobacterium aurum, Mycobacterium smegmatis and Mycobacterium tuberculosis. (8/492)
The characteristics of the accumulation of 2 mg/L [(14)C]rifampicin by wild-type strains of Mycobacterium aurum (A(+)), Mycobacterium smegmatis (mc(2)155) and Mycobacterium tuberculosis (H37Rv) were determined. After 10 min exposure M. aurum had accumulated 220 ng rifampicin/mg cells, M. smegmatis had accumulated 120 ng rifampicin/mg cells and M. tuberculosis had accumulated 154 ng rifampicin/mg cells. A steady-state concentration (SSC) of rifampicin was accumulated rapidly by M. aurum and M. tuberculosis within minutes of drug exposure, unlike M. smegmatis, which accumulated rifampicin more slowly. With an increase in the concentration of rifampicin from 0.12 mg/L to 2 mg/L there was an increase in the concentration of rifampicin accumulated by M. tuberculosis, with no detectable loss of viability over the 20 min of the accumulation experiment. With an increase in temperature there was also an increase in the concentration of rifampicin accumulated by M. tuberculosis; between 15 and 30 degrees C the increase was linear. For all three species sub-inhibitory concentrations of ethambutol increased the concentration of rifampicin accumulated. However, both growth and accumulation of rifampicin were lower in the presence of 0.05% Tween 80. Accumulation of rifampicin by M. smegmatis was unaffected by the presence of the proton motive force inhibitor, 2,4-dinitrophenol (1 mM), whether added before or after the addition of rifampicin to the mycobacterial culture. For all three species, the Gram-positive bacterial efflux inhibitor reserpine (20 mg/L) slightly increased the SSC of rifampicin, but the increase was not statistically significant. Addition of glucose to energize a putative efflux pump had little effect on the accumulation of rifampicin in the presence or absence of reserpine for M. tuberculosis; however, for M. aurum and M. smegmatis the reserpine effect was abolished by the addition of glucose. These data suggest that rifampicin may be removed from wild-type mycobacteria by efflux, but that the pump(s) is expressed at low level. (+info)Polysorbates are a type of nonionic surfactant (a compound that lowers the surface tension between two substances, such as oil and water) commonly used in pharmaceuticals, foods, and cosmetics. They are derived from sorbitol and reacted with ethylene oxide to create a polyoxyethylene structure. The most common types of polysorbates used in medicine are polysorbate 20, polysorbate 40, and polysorbate 60, which differ in the number of oxyethylene groups in their molecular structure.
Polysorbates are often added to pharmaceutical formulations as emulsifiers, solubilizers, or stabilizers. They help to improve the solubility and stability of drugs that are otherwise insoluble in water, allowing for better absorption and bioavailability. Polysorbates can also prevent the aggregation and precipitation of proteins in injectable formulations.
In addition to their use in pharmaceuticals, polysorbates are also used as emulsifiers in food products such as ice cream, salad dressings, and baked goods. They help to mix oil and water-based ingredients together and prevent them from separating. In cosmetics, polysorbates are used as surfactants, solubilizers, and stabilizers in a variety of personal care products.
It is important to note that some people may have allergic reactions to polysorbates, particularly those with sensitivities to sorbitol or other ingredients used in their production. Therefore, it is essential to carefully consider the potential risks and benefits of using products containing polysorbates in individuals who may be at risk for adverse reactions.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
Medical Definition of Monoglycerides:
Monoglycerides are types of glycerides that contain one molecule of fatty acid combined with a glycerol molecule through an ester linkage. They are often used as food additives, serving as emulsifiers to help blend together water and oil-based ingredients in foods such as baked goods, ice cream, and chocolate. Monoglycerides can also be found naturally in some foods, including certain vegetable oils.
In the context of human physiology, monoglycerides can serve as a source of energy and can also play a role in the absorption and transport of fatty acids in the body. However, they are not typically considered to be a major nutrient or component of the human diet.
Spiroplasmataceae is a family of bacteria that are characterized by their unique lack of a cell wall and their spiral or helical shape. They belong to the class Mollicutes, which includes other wall-less bacteria such as Mycoplasma and Ureaplasma. Spiroplasmataceae are distinguished from other Mollicutes by their distinctive corkscrew-like morphology and their ability to move via flexing or twisting motions.
Members of this family are typically associated with plants, insects, and other invertebrates, and some have been found to be pathogenic or mutualistic symbionts. For example, the genus Spiroplasma includes several species that can cause diseases in insects and plants, while other species are known to have beneficial relationships with their hosts.
Spiroplasmataceae are fastidious organisms, requiring complex media for growth in the laboratory. They are also resistant to many antibiotics due to their lack of a cell wall and their small genome size. Further research is needed to fully understand the biology and ecology of these fascinating bacteria.
"Laureates" is not a medical term. However, if you are referring to "laurates" as a salt or ester of lauric acid, then here's the definition:
Laurates are organic compounds that contain a laurate group, which is the anion (negatively charged ion) derived from lauric acid. Lauric acid is a saturated fatty acid with a 12-carbon chain, and its anion has the chemical formula CH3(CH2)10COO-.
Laurates can be formed by reacting lauric acid with a base to form a salt (e.g., sodium laurate, potassium laurate) or by reacting it with an alcohol to form an ester (e.g., methyl laurate, ethyl laurate). These compounds have various applications in industry, including as surfactants, emulsifiers, and solubilizers in personal care products, cosmetics, and pharmaceuticals.
Mycoplasmataceae is a family of bacteria that lack a cell wall and are characterized by their small size. They are among the smallest self-replicating organisms, with some species measuring only 0.15 microns in diameter. Mycoplasmataceae are unique because they possess a membrane-anchored lipoprotein instead of a cell wall, which makes them resistant to many antibiotics that target cell wall synthesis.
Members of this family are commonly found as commensals or opportunistic pathogens in humans and animals. They can cause a variety of diseases, including respiratory tract infections, urinary tract infections, and arthritis. Mycoplasmataceae are also known to contaminate cell cultures and can interfere with research experiments.
Some notable genera within the family Mycoplasmataceae include Mycoplasma, Ureaplasma, and Acholeplasma.
Poloxalene is not a medical term, but a chemical compound. It's an ether used as a non-ionic surfactant and emulsifying agent in the pharmaceutical industry. Poloxalene is also known for its ability to reduce the severity of bloat (gas distention) in animals, particularly in ruminants like cows, when included in their feed. However, it's not typically used as a human medication.
Polysorbate
Polysorbate 20
Polysorbate 80
Sorbitan monopalmitate
Sorbitan tristearate
Zippy the Pinhead
Immunologic adjuvant
Docetaxel
Sorbitan
Scooba (brand)
Polyethylene glycol
Emulsion
Nanoparticles for drug delivery to the brain
TBST
Shoe polish
MRS agar
Ice cream
Ethoxylation
Sorbic acid
Phenotypic testing of mycobacteria
Evofosfamide
Food safety
Þórdís Kristmundsdóttir
Topical fluoride
Cinnamon
Haloterrigena turkmenica
Discovery and development of tubulin inhibitors
Sputnik V COVID-19 vaccine
Scope (mouthwash)
Kluyveromyces marxianus
Polysorbate - Wikipedia
CPG Sec 555.800 Polysorbates 20, 40, 60, 65, 80, 85 - Common or Usual Names | FDA
Darbepoetin Alfa In Polysorbate Subcutaneous: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
BD DIFCO™ Butterfields with Lecithin and Polysorbate 80 10pk - 292955 | BD
DailyMed - REFRESH OPTIVE ADVANCED- carboxymethylcellulose sodium, glycerin, polysorbate 80 solution/ drops
Solubilizer (Polysorbate 20) | PerfumersWorld
Polysorbate 20 (Solubilizer), Sweetcakes
What are Polysorbates: Chemical Free Living - Force of Nature
Polysorbate 20
Loterre: CHEBI: polysorbate 80
Polysorbate 20 - Creme Compagniet
Polysorbate 80 - Colin's Beauty Pages
Polysorbate 80 - Solubilisers & Emulsifiers - Freshskin Beauty
Kolliphor® PS 20
Polysorbate 20 - Solubilisator | Made By Me
polysorbate 80 in skincare, What is? | Lesielle
Is polysorbate bad for dogs? - Animal Shelters
Polysorbate 20 (Cosmetic Grade) 100 ml - Leonardi Laboratories
Polysorbate-20 Archives - Maas MD & Warren MD Skincare
No comment
Polysorbate 80: A Risky Vaccine Ingredient - The Vaccine Reaction
Polysorbate 80 in Vaccines: Is it safe? - Truth Snitch
Polysorbate/Tween 20 60 80 CAS 9005-64-5
Buy Polysorbate 80 At Affordable Price Online - Make Your Own
Polysorbate 80 (Tween 80) - Elsie Organics - Formulation Ingredients Shop Nigeria
Polysorbate 20 (9005-64-5) | Chemical Effects in Biological Systems
polysorbate replacement Archives * Bath Bomb Press | Fragrance Oils | Mica | Essential Oil
4oz Polysorbate 80 Emulsifier - Mix Water & Oil Create Emulsions Cream - ModelSupplies
Best Non-Toxic All-Purpose Cleaners 2022
Surfactant13
- Polysorbate 20 is a vegetable-derived non-ionic surfactant containing ethylene oxide. (animalshelterz.com)
- Functions: Polysorbate 20 is used in cosmetics and skin care products as a surfactant, emulsifier, and fragrance ingredient. (animalshelterz.com)
- Polysorbate 20 (commercially called Tween 20) is derived from sorbitol, a natural sugar alcohol and forms a polysorbate-type nonionic surfactant by the ethoxylation of sorbitan (derived from the dehydration of sorbitol) before the addition of lauric acid. (animalshelterz.com)
- Polysorbate 20 (common commercial brand names include Kolliphor PS 20, Scattics, Alkest TW 20, Tween 20, and Kotilen-20) is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan monolaurate. (animalshelterz.com)
- Polysorbate 20 / Tween 20 is a polysorbate surfactant used as emulsifier and wetting agent. (foodsweeteners.com)
- POLYSORBATE 80, sometimes referred to by trade names like Poly 80 or Tween 80, is a non ionic emulsifier and surfactant used for blending many oil based and water based ingredients and additives in to formulations together for dispersing, emulsifying and more. (makeyourown.buzz)
- Polysorbate 80, a surfactant, is an ingredient used in several vaccines. (thevaccinereaction.org)
- Polysorbate 80 is a surfactant commonly used in the pharmaceutical, cosmetic and food industry. (thevaccinereaction.org)
- Polysorbate/Tween 80 is nonionic surfactant and emulsifier. (lugchemical.co.id)
- Polysorbate/Tween 80 is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops. (lugchemical.co.id)
- Polysorbate/Tween 80 can be also used as a solubilizing agent acts as a surfactant and increases the solubility of one agent in another. (lugchemical.co.id)
- Formation of mixed micelles consisting of nonionic surfactant polysorbate 80 and cationic amiodarone with chloride counterion was investigated by fluorescence spectroscopy. (kyobobook.co.kr)
- Polysorbate 80 is a surfactant, meaning it helps connect oil and water, and it can be used to make bath bombs less "greasy" and increase lather. (liquidimageco.com)
Emulsifier9
- Polysorbate 80 is used as a non-ionic, hydrophilic emulsifier for cosmetic and pharmaceutical creams and ointments. (freshskin.co.uk)
- Polysorbate 20 is used as a high HLB emulsifier in combination with a variety low HLB emulsifiers to cover a wide range of oil in water, and water in oil emulsion systems. (leonardi.com.au)
- Polysorbate 20 is regarded as a safe chemical in skincare and is used as an emulsifier to combine oil and water. (animalshelterz.com)
- Buy Polysorbate 80 to use as an emulsifier, stabilizer, and/ or solubilizer in your cream/ lotion or other cosmetic formulation. (elsieorganics.com)
- In vaccines, Polysorbate 80 acts as an emulsifier to disperse all the other ingredients evenly within the liquid. (thevaccinereaction.org)
- Polysorbate 80 is used as an emulsifier/stabilizer in vaccines, but you won't find any safety information from CDC documents. (truthsnitch.com)
- Second, polysorbate 80 has been used for years as an emulsifier to make ice cream smooth and to slow melting. (truthsnitch.com)
- Polysorbate 20 60 80 / Tween 20 60 80 is used as O/W food emulsifier, it can be used alone or mixed with Span-60, Span-65, Span-80. (richest-food.com)
- Polysorbate/Tween 80 is also known as an emulsifier, which helps ingredients mix together and prevent separation. (lugchemical.co.id)
Emulsifiers3
- Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. (wikipedia.org)
- The polysorbates were pioneered by ICI and are used as solubilisers and emulsifiers. (colinsbeautypages.co.uk)
- The two emulsifiers are polysorbate 80 and carboxymethylcellulose. (animalshelterz.com)
Ingredient10
- Health concerns related to the presence of polysorbates and impurities related to this ingredient include cancer (due to ethylene oxide and 1,4 dioxane ), skin allergies, developmental toxicity, reproductive toxicity. (forceofnatureclean.com)
- https://www.ewg.org/skindeep/ingredient/705137/POLYSORBATE-20/ December 20, 2016. (forceofnatureclean.com)
- How come they're called Tweens in the lab and Polysorbates in food and cosmetic ingredient lists? (colinsbeautypages.co.uk)
- Is polysorbate a natural ingredient? (animalshelterz.com)
- Polysorbate 80 is a synthetic ingredient, synthesized through dehydration of sorbitol, esterification with oleic acid, and etherification with ethylene oxide. (animalshelterz.com)
- Pediatrician Lawrence Palevsky, MD warns of the potential danger of using Polysorbate 80 as a vaccine ingredient. (thevaccinereaction.org)
- We'll talk about one such ingredient today- polysorbate 80. (truthsnitch.com)
- Tell your doctor if you are allergic to docetaxel injection or drugs made with polysorbate 80, an ingredient found in some medications. (medlineplus.gov)
- any ingredient in the J&J/Janssen COVID-19 vaccine (such as polysorbate), you should not get the J&J/Janssen COVID-19 vaccine. (cdc.gov)
- For this reason, CDC recommends that people who have had a severe or immediate reaction to the vaccine, any ingredient in the vaccine, or to polysorbate (which is closely related to PEG) not receive the mRNA vaccines. (cdc.gov)
Tween 202
- Polysorbate 20, også kjent som tween 20, en O/W (oil in water) ikke-ionisk emulgator, egnet for kremer, flytende emulsjoner og som solubilisator for eteriske oljer. (madebyme.no)
- Polysorbate 20/Tween 20 E432 can be used in Food, Beverage, Pharmaceutical, Health & Personal care products, Agriculture/Animal Feed/Poultry. (foodsweeteners.com)
Contains polysorbate 802
- The HPV vaccine contains polysorbate 80 as a stabilizer. (truthsnitch.com)
- Ask your doctor if you are unsure if a medication you are allergic to contains polysorbate 80. (medlineplus.gov)
Nonionic1
- Polysorbate 20 E432 is a series of general purpose hydrophilic, nonionic surfactants. (foodsweeteners.com)
Sorbitan tristearate1
- 3) Pursuant to Annex II to Regulation (EC) No 1333/2008, polyoxyethylene sorbitan tristearate (polysorbate 65) (E 436) is currently authorised for use as a food additive in the group 'polysorbates' (E 432-436) in a wide variety of foods at maximum levels ranging between 500 and 10 000 mg/kg and quantum satis in food supplements. (alfachemic.com)
Formed by the ethoxylation of sorbitan1
- Polysorbate 80 is formed by the ethoxylation of sorbitan. (lesielle.com)
Excipient4
- Polysorbate 20 E432 can be used as an excipient in the stabilization of suspensions and emulsions. (foodsweeteners.com)
- The Drugs.com definition states: "Polysorbate 80 is a common excipient and solubilizing agent used in the pharmaceutical industry. (truthsnitch.com)
- Polysorbate 80 (also known as polyoxyethylene-sorbitan-20 mono-oleate, or Tween 80) is used in the pharmaceutical and cosmetic industry in lotions, medical preparations (eg vitamin oils, vaccines, and intravenous preparations) and as an excipient in tablets. (truthsnitch.com)
- Polysorbate/Tween 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration or vaccinations. (lugchemical.co.id)
Surfactants2
- Polysorbates are used in cleaners and personal care products as fragrance ingredients, emulsifying agents, and as surfactants [1]. (forceofnatureclean.com)
- A formulation strategy involving optimization of colloidal stability of the antibody as well as incorporation of surfactants such as polysorbate 20 is proposed to reduce silicone oil-induced aggregation of therapeutic protein products. (nih.gov)
Ethylene oxide1
- One of the biggest concerns regarding polysorbates is the presence of carcinogens including ethylene oxide and 1,4 dioxane . (forceofnatureclean.com)
Solubilizer3
- Solubilizer (Polysorbate 20) is a water solubiliser for essential oils and perfume compounds. (perfumersworld.com)
- Polysorbate 20 is a gentle, non-irritating, non-toxic solubilizer. (sweetcakes.com)
- Polysorbate 20 can serve as a dispersing agent and mix oil and water, work as a fragrance solubilizer and stabilizer, act as a lubricator, and have a soothing effect on the skin (NatureBath.com). (animalshelterz.com)
Polyoxyethylene sorbitan1
- However, there are other concerning ingredients in vaccines that are not talked about as often, one of which is Polysorbate 80-also known as Tween 80 and polyoxyethylene-sorbitan-20 mono-oleate. (thevaccinereaction.org)
Ingredients7
- The polysorbate 80 will do a good job of allowing the oil to rinse off well, and there aren't really any natural ingredients that will have the same effect. (colinsbeautypages.co.uk)
- Avoid buying dog shampoos and conditioners that contain any reference to polysorbates or ethoxylated ingredients. (animalshelterz.com)
- The name you see in a dog shampoo's ingredients list will have the word polysorbate followed by a number. (animalshelterz.com)
- The Polysorbate ingredients help other ingredients to dissolve in a solvent in which they would not normally dissolve. (foodsweeteners.com)
- This raises serious concerns of using Polysorbate 80 in combination with other reactive vaccine ingredients, which have the potential to damage the brain. (thevaccinereaction.org)
- Consequently, the concern with using Polysorbate 80 in vaccines is that it may permit the entry of other toxic ingredients, such as heavy metals, into the brain. (thevaccinereaction.org)
- In general, you can omit polysorbate 80 if you would like to, as long as you compensate for its emulsifying effects by adding other ingredients that can bring your bath bomb together. (liquidimageco.com)
Emulsions1
- Polysorbate 20 also help to form emulsions by reducing the surface tension of the substances to be emulsified. (foodsweeteners.com)
Excipients2
Vaccine3
- The fact that Polysorbate 80 "may cause cancer based on animal test data" and may be mutagenic alone should be enough to require vaccine manufacturers and the Food and Drug Administration to provide credible scientific evidence that it is safe to include Polysorbate 80 in vaccines given to humans. (thevaccinereaction.org)
- Some stories on the internet have suggested that polysorbate 80 in this vaccine causes infertility. (truthsnitch.com)
- On the other hand, the amount of polysorbate 80 in each dose of the HPV vaccine- 50 micrograms- is very small. (truthsnitch.com)
Liquids2
- Polysorbates are oily liquids derived from ethoxylated sorbitan (a derivative of sorbitol) esterified with fatty acids. (wikipedia.org)
- To prevent separation of liquids, Polysorbate 80 is present in several formulas such as skin care products, shampoos, makeup, ice-cream, processed salad dressings and sauces. (thevaccinereaction.org)
Humans1
- Is Polysorbate 20 harmful to humans? (animalshelterz.com)
Bath Bombs3
- Is polysorbate 80 necessary in bath bombs? (liquidimageco.com)
- The use of polysorbate 80 in bath bombs is a matter of preference, rather than necessity. (liquidimageco.com)
- So, whether or not polysorbate 80 is necessary in bath bombs is up to individual preference. (liquidimageco.com)
Reproductive effects1
- According to the Journal of National Cancer Institute, the Journal of Nutrition and the FAO Nutrition Meetings Report Series, polysorbate 60 can cause detrimental reproductive effects, organ toxicity and cancer in high doses. (animalshelterz.com)
Skincare1
- polysorbate 80 in skincare, What is? (lesielle.com)
Products6
- Read the labels on personal care products, tampons, and cleaners to avoid polysorbates whenever possible. (forceofnatureclean.com)
- Polysorbate 80 is widely enough used in food products for many people to recognise the name. (colinsbeautypages.co.uk)
- The application of Polysorbate 20 E432 in food such as in whipped toppings, salad dressings, salad dressings, cakes and cake mixes, edible oils, cake icings and fillings, dairy product substitutes, chocolate syrups, confectionary coatings and cocoa products, mineral oils and waxes for use in protective coatings for fruits and vegetables. (foodsweeteners.com)
- The Polysorbates are used in a variety of products including skin fresheners, skin care products, skin cleansing products, makeup bases and foundations, shampoos, permanent waves and fragrance powders. (foodsweeteners.com)
- Polysorbate 20 E432 can be used as emulsify and act as a detergent in floor cleaners and other cleaning products. (foodsweeteners.com)
- But it's important to remember that polysorbate 80 is widely used in cosmetics and beauty products, so it is generally considered to be safe. (liquidimageco.com)
Viscous1
- Polysorbate/Tween 80 is viscous, water-soluble yellow liquid. (lugchemical.co.id)
Fatty acid2
- Polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate) Polysorbate 40 (polyoxyethylene (20) sorbitan monopalmitate) Polysorbate 60 (polyoxyethylene (20) sorbitan monostearate) Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate) The number following the 'polysorbate' part is related to the type of major fatty acid associated with the molecule. (wikipedia.org)
- Polysorbate-20 is made from polyethoxylated sorbitan (chemical compounds derived from the dehydration of sugar alcohol) and oleic acid, a fatty acid found in vegetable fats. (animalshelterz.com)
Formulations1
- Polysorbates in combination with some related materials have enabled a lot of formulations that would otherwise be either impossible or far from attractive to be created. (colinsbeautypages.co.uk)
Vaccines4
- There is glaring lack of research evaluating the risks to human health of including Polysorbate 80 in vaccines. (thevaccinereaction.org)
- Polysorbate 80 in Vaccines: Is it safe? (truthsnitch.com)
- Therefore, polysorbate 80 isn't contained in vaccines at quantities that could possibly do harm. (truthsnitch.com)
- The amount of polysorbate 80 in vaccines can't possibly harm me? (truthsnitch.com)
Pharmacology1
- Polysorbate 80 is used in pharmacology to assist in the delivery of certain drugs or chemotherapeutic agents across the blood-brain-barrier. (thevaccinereaction.org)
Endless1
- Polysorbate 80 has endless possibilities. (makeyourown.buzz)
Synonyms1
- Be sure to look for synonyms (listed above) used to designate the presence of polysorbates. (forceofnatureclean.com)
Allergic1
- This drug must not be used in patients who have previously had an allergic reaction to it or to other medications containing polysorbate 80. (webmd.com)
Sorbitol1
- In its natural form, a polysorbate is a harmless sugar alcohol (a sorbitol). (animalshelterz.com)
Dietary2
- No adverse effects such as diarrhea were observed in a 1-year dietary administration of polysorbate 60 to dogs (5% and 10%)25). (animalshelterz.com)
- The Authority noted that more data were needed to decrease uncertainties in the refined exposure assessment scenario used since no reported uses had been obtained for three food categories and that other dietary sources of exposure to polysorbates could not be considered in the opinion. (alfachemic.com)
Injection1
- 6 The MSDS does not address the effects of polysorbate through injection. (thevaccinereaction.org)
Product2
- Is Polysorbate 20 a natural product? (animalshelterz.com)
- Polysorbate 20 E432 can be used in food such as in whipped toppings, salad dressings, salad dressings, cakes and cake mixes, edible oils, cake icings and fillings, dairy product substitutes, chocolate syrups. (foodsweeteners.com)
Fragrance oils1
- Combine equal amounts of Polysorbate 20 and the essential and/or fragrance oils you plan to use. (sweetcakes.com)
Food4
- Polysorbates aren't really what you could call green, but they are certainly safe as their use in food shows. (colinsbeautypages.co.uk)
- Is polysorbate 80 safe in our food? (truthsnitch.com)
- 7) The safety of polysorbates (E 432-436) used as food additives was re-evaluated by the Authority in 2015 ( 3 ). (alfachemic.com)
- Polysorbates are gaining prominence as food preservatives due to their detergency and emulsification properties, which improve the texture and shelf life of processed foods. (reportlinker.com)
Include1
- However, many bath bomb recipes do not include polysorbate 80 and still get great results. (liquidimageco.com)
Combine1
- Polysorbate-20 can be used where you need water and oil to combine, room fragrances for example. (animalshelterz.com)
Vegetable1
- Polysorbate 80 is typically derived from vegetable oils like olive oil. (makeyourown.buzz)
Water2
- Mix the Polysorbate with the oil or perfume compound well then add the water slowly, stirring all the time. (perfumersworld.com)
- This paper aimed to study the effect of polysorbate 80 and benzyl alcohol on the water solubility of amiodarone hydrochloride. (kyobobook.co.kr)
Https1
- https://householdproducts.nlm.nih.gov/cgi-bin/household/brands?tbl=chem&id=65&query=polysorbate&searchas=TblChemicals January 23, 2107. (forceofnatureclean.com)
Study2
- Study results of the polysorbates, showed no carcinogenicity and genotoxicity. (animalshelterz.com)
- This 2015 study also linked polysorbate 80 to gut inflammation, negatively altered gut bacteria (we now know that a healthy gut biome is necessary for immune function), obesity and metabolic syndromes. (truthsnitch.com)
Results1
- 5) It results from the application that, the proposed use of polysorbate 65 (E 436) is required at the maximum level of 10 mg/kg for containment and inhibition of foam during the manufacture of carbonated beverages by forming a layer around bubbles and stabilising larger bubbles preventing them to coalesce and break. (alfachemic.com)
Safe4
- Is Polysorbate 20 safe to use? (animalshelterz.com)
- Is polysorbate safe for dogs? (animalshelterz.com)
- Is polysorbate safe on skin? (animalshelterz.com)
- If by safe you merely mean that you don't drop dead immediately from ingesting it, then polysorbate 80 fits that description. (truthsnitch.com)