Chemicals and DrugsTechnology, Industry, Agriculture
Polysorbates
Polysorbates
Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.

Bacteriophage inactivation at the air-water-solid interface in dynamic batch systems. (1/492)

Bacteriophages have been widely used as surrogates for human enteric viruses in many studies on virus transport and fate. In this investigation, the fates of three bacteriophages, MS2, R17, and phiX174, were studied in a series of dynamic batch experiments. Both MS2 and R17 readily underwent inactivation in batch experiments where solutions of each phage were percolated through tubes packed with varying ratios of glass and Teflon beads. MS2 and R17 inactivation was the result of exposure to destructive forces at the dynamic air-water-solid interface. phiX174, however, did not undergo inactivation in similar studies, suggesting that this phage does not accumulate at air-water interfaces or is not affected by interfacial forces in the same manner. Other batch experiments showed that MS2 and R17 were increasingly inactivated during mixing in polypropylene tubes as the ionic strength of the solution was raised (phiX174 was not affected). By the addition of Tween 80 to suspensions of MS2 and R17, phage inactivation was prevented. Our data suggest that viral inactivation in simple dynamic batch experiments is dependent upon (i) the presence of a dynamic air-water-solid interface (where the solid is a hydrophobic surface), (ii) the ionic strength of the solution, (iii) the concentration of surface active compounds in the solution, and (iv) the type of virus used.  (+info)

Comparison of immunity generated by nucleic acid-, MF59-, and ISCOM-formulated human immunodeficiency virus type 1 vaccines in Rhesus macaques: evidence for viral clearance. (2/492)

The kinetics of T-helper immune responses generated in 16 mature outbred rhesus monkeys (Macaca mulatta) within a 10-month period by three different human immunodeficiency virus type 1 (HIV-1) vaccine strategies were compared. Immune responses to monomeric recombinant gp120SF2 (rgp120) when the protein was expressed in vivo by DNA immunization or when it was delivered as a subunit protein vaccine formulated either with the MF59 adjuvant or by incorporation into immune-stimulating complexes (ISCOMs) were compared. Virus-neutralizing antibodies (NA) against HIV-1SF2 reached similar titers in the two rgp120SF2 protein-immunized groups, but the responses showed different kinetics, while NA were delayed and their levels were low in the DNA-immunized animals. Antigen-specific gamma interferon (IFN-gamma) T-helper (type 1-like) responses were detected in the DNA-immunized group, but only after the fourth immunization, and the rgp120/MF59 group generated both IFN-gamma and interleukin-4 (IL-4) (type 2-like) responses that appeared after the third immunization. In contrast, rgp120/ISCOM-immunized animals rapidly developed marked IL-2, IFN-gamma (type 1-like), and IL-4 responses that peaked after the second immunization. To determine which type of immune responses correlated with protection from infection, all animals were challenged intravenously with 50 50% infective doses of a rhesus cell-propagated, in vivo-titrated stock of a chimeric simian immunodeficiency virus-HIVSF13 construct. Protection was observed in the two groups receiving the rgp120 subunit vaccines. Half of the animals in the ISCOM group were completely protected from infection. In other subunit vaccinees there was evidence by multiple assays that virus detected at 2 weeks postchallenge was effectively cleared. Early induction of potent type 1- as well as type 2-like T-helper responses induced the most-effective immunity.  (+info)

Purification and characterization from rat kidney membranes of a novel platelet-activating factor (PAF)-dependent transacetylase that catalyzes the hydrolysis of PAF, formation of PAF analogs, and C2-ceramide. (3/492)

We have previously identified two enzyme activities that transfer the acetyl group from platelet-activating factor (PAF) in a CoA-independent manner to lysoplasmalogen or sphingosine in HL-60 cells, endothelial cells, and a variety of rat tissues. These were termed as PAF:lysoplasmalogen (lysophospholipid) transacetylase and PAF:sphingosine transacetylase, respectively. In the present study, we have solubilized and purified this PAF-dependent transacetylase 13,700-fold from rat kidney membranes (mitochondrial plus microsomal membranes) based on the PAF:lysoplasmalogen transacetylase activity. The mitochondria and microsomes were prepared and washed three times, then solubilized with 0.04% Tween 20 at a detergent/protein (w/w) ratio of 0.1. The solubilized fractions from mitochondria and microsomes were combined and subjected to sequential column chromatographies on DEAE-Sepharose, hydroxyapatite, phenyl-Sepharose, and chromatofocusing. The enzyme was further purified by native-polyacrylamide gel electrophoresis (PAGE) and affinity gel matrix in which the competitive inhibitor of the enzyme, 1-O-hexadecyl-2-N-methylcarbamyl-sn-glycero-3-phosphoethanolamine was covalently attached to the CH-Sepharose. On SDS-PAGE, the purified enzyme showed a single homogeneous band with an apparent molecular mass of 40 kDa. The purified enzyme catalyzed transacetylation of the acetyl group not only from PAF to lysoplasmalogen forming plasmalogen analogs of PAF, but also to sphingosine producing N-acetylsphingosine (C2-ceramide). In addition, this enzyme acted as a PAF-acetylhydrolase in the absence of lipid acceptor molecules. These results suggest that PAF-dependent transacetylase is an enzyme that modifies the cellular functions of PAF through generation of other diverse lipid mediators.  (+info)

Enzymatic properties of vesicle-reconstituted human cytochrome P450SCC (CYP11A1) differences in functioning of the mitochondrial electron-transfer chain using human and bovine adrenodoxin and activation by cardiolipin. (4/492)

The recently reported heterologous expression and purification of both human cytochrome P450SCC and adrenodoxin [Woods, S.T., Sadleir, J., Downs, T., Triantopoulos, T., Haedlam, M.J. & Tuckey, R.C. (1998) Arch. Biochem. Biophys. 353, 109-115] has enabled us to perform studies with the membrane-reconstituted human enzymes to better understand the side-chain cleavage reaction in humans. Human P450SCC was successfully reconstituted into dioleoylphosphatidylcholine vesicles with and without cardiolipin and its enzymatic properties characterized in the membrane-bound state. Enhancement of the P450SCC activity and significant activation by cardiolipin were observed when human adrenodoxin instead of bovine adrenodoxin was used as electron donor. In the absence of cardiolipin, Km for cholesterol was decreased twice in the case of human adrenodoxin indicating enhanced cholesterol binding. On the other hand, in the presence of cardiolipin in the membrane both Km and V for cholesterol were decreased with human adrenodoxin as electron donor. Kinetic analysis of the interaction between human P450SCC and its redox partners provided evidence for enhanced binding of the human electron donor to human P450SCC indicated by both an increased V and decreased Kd for human adrenodoxin compared with the values with bovine adrenodoxin. Because no similar effects were observed in Tween 20 micelles, these results suggest that the phospholipid membrane may play an important role in the interaction of human adrenodoxin with human P450SCC.  (+info)

Virus passage through track-etch membranes modified by salinity and a nonionic surfactant. (5/492)

Why do viruses sometimes not pass through larger pores in track-etch filters? Increasing the salinity (0.8 to 160 mM Na+) decreased phiX174 and PRD1 passage through track-etch polycarbonate membranes (sodium dodecyl sulfate coated but not polyvinylpyrrolidone coated) and PRD1 passage through polyester membranes. Undiminished passage when 0.1% Tween 80 was added implied that nonionic virus adsorption occurred and indicated that high levels of salinity decreased virus passage by decreasing electrostatic repulsion that prevented adsorption.  (+info)

Rapid esterase-sensitive breakdown of polysorbate 80 and its impact on the plasma pharmacokinetics of docetaxel and metabolites in mice. (6/492)

We have developed and validated an analytical methodology for the quantification of docetaxel and its four major human oxidation metabolites in mouse plasma. We have used this procedure to study the pharmacokinetics and metabolism of docetaxel in female FVB mice, receiving 2.5, 10, or 33 mg/kg of docetaxel by i.v. injection. We have also studied the pharmacokinetics of polysorbate 80, because it was shown previously that the vehicle substance Cremophor EL, which is used in the formulation of paclitaxel, exerts a profound effect on the pharmacokinetics of this compound. Linear pharmacokinetics of docetaxel was observed at dose levels between 2.5 and 10 mg/kg, where plasma levels corresponded to those in patients receiving the maximum tolerated dose. At the highest dose level of 33 mg/kg, a deviation from the linear kinetics was observed. Compared with humans, mice could tolerate much higher plasma levels, suggesting that the toxic side effects are related to a certain plasma threshold concentration instead of area under the curve or Cmax. At the highest dose level, three docetaxel metabolites could be detected in the plasma samples of mice for up to 4 h after drug administration. The hydroxy metabolite of the tert-butoxy group (metabolite II) was the major metabolite, followed by the two epimeric hydroxyoxazolone-type compounds (metabolites I and III). A fourth putative metabolite (e.g., the cyclic oxazolidinedione derivative) was not detected. Because of rapid degradation of polysorbate 80 by esterases in plasma, the concentration of this vehicle substance declined very rapidly. Consequently, this substance was not able to interfere in the disposition of docetaxel.  (+info)

A novel surfactant nanoemulsion with broad-spectrum sporicidal activity against Bacillus species. (7/492)

Two nontoxic, antimicrobial nanoemulsions, BCTP and BCTP 401, have been developed. These emulsions are composed of detergents and oils in 80% water. BCTP diluted up to 1:1000 inactivated>90% of Bacillus anthracis spores in 4 h and was also sporicidal against three other Bacillus species. This sporicidal activity is due to disruption of the spore coat after initiation of germination without complete outgrowth. BCTP 401 diluted 1:1000 had greater activity than BCTP against Bacillus spores and had an onset of action of <30 min. Mixing BCTP or BCTP 401 with Bacillus cereus prior to subcutaneous injection in mice reduced the resulting skin lesion by 99%. Wound irrigation with BCTP 1 h after spore inoculation yielded a 98% reduction in skin lesion size, and mortality was reduced 3-fold. These nanoemulsion formulas are stable, easily dispersed, nonirritant, and nontoxic compared with other available sporicidal agents.  (+info)

Accumulation of rifampicin by Mycobacterium aurum, Mycobacterium smegmatis and Mycobacterium tuberculosis. (8/492)

The characteristics of the accumulation of 2 mg/L [(14)C]rifampicin by wild-type strains of Mycobacterium aurum (A(+)), Mycobacterium smegmatis (mc(2)155) and Mycobacterium tuberculosis (H37Rv) were determined. After 10 min exposure M. aurum had accumulated 220 ng rifampicin/mg cells, M. smegmatis had accumulated 120 ng rifampicin/mg cells and M. tuberculosis had accumulated 154 ng rifampicin/mg cells. A steady-state concentration (SSC) of rifampicin was accumulated rapidly by M. aurum and M. tuberculosis within minutes of drug exposure, unlike M. smegmatis, which accumulated rifampicin more slowly. With an increase in the concentration of rifampicin from 0.12 mg/L to 2 mg/L there was an increase in the concentration of rifampicin accumulated by M. tuberculosis, with no detectable loss of viability over the 20 min of the accumulation experiment. With an increase in temperature there was also an increase in the concentration of rifampicin accumulated by M. tuberculosis; between 15 and 30 degrees C the increase was linear. For all three species sub-inhibitory concentrations of ethambutol increased the concentration of rifampicin accumulated. However, both growth and accumulation of rifampicin were lower in the presence of 0.05% Tween 80. Accumulation of rifampicin by M. smegmatis was unaffected by the presence of the proton motive force inhibitor, 2,4-dinitrophenol (1 mM), whether added before or after the addition of rifampicin to the mycobacterial culture. For all three species, the Gram-positive bacterial efflux inhibitor reserpine (20 mg/L) slightly increased the SSC of rifampicin, but the increase was not statistically significant. Addition of glucose to energize a putative efflux pump had little effect on the accumulation of rifampicin in the presence or absence of reserpine for M. tuberculosis; however, for M. aurum and M. smegmatis the reserpine effect was abolished by the addition of glucose. These data suggest that rifampicin may be removed from wild-type mycobacteria by efflux, but that the pump(s) is expressed at low level.  (+info)

PROCESS FOR PREPARING AN OLEOGEL - Patent applicationPROCESS FOR PREPARING AN OLEOGEL - Patent application
0049] Although a stabilizer is not necessary to prepare the oleogel, it may be added in certain embodiments to modify the properties of the oleogel, such as to increase its firmness. The stabilizer can be one that is either suitable or not suitable for use in the preparation of food, depending on the desired end use of the oleogel. Examples of stabilizers that may be used in the present process are food grade surfactants and emulsifiers such as polyoxyethylene sorbitan monooleate (Tween 80 or Polysorbate 80); polyoxyethylene sorbitan tristearate (Tween 65 or Polysorbate 65); polyoxyethylene sorbitan monostearate (Tween 60 or Polysorbate 60); sorbitan monooleate (SMO or Span 80); sorbitan monostearate (SMS or Span 60); glyceryl monooleate (GMO); glyceryl monostearate (GMS); glyceryl monopalmitate (GMP); polyglycerol esters such as polyglyceryl ester of lauric acid-polyglyceryl polylaurate (PGPL), polyglyceryl ester of stearic acid-polyglyeryl polystearate (PGPS), polyglyceryl ester of oleic ...
http://www.patentsencyclopedia.com/app/20160081374
Find Suppliers & Manufacturers (CMOs / CDMOs) of Parenteral Excipients For Ophthalmic Solution of Sorbitan MonooleateFind Suppliers & Manufacturers (CMOs / CDMOs) of Parenteral Excipients For Ophthalmic Solution of Sorbitan Monooleate
Search PharmaCompass to Find Suppliers & Manufacturers of Sorbitan Monooleate, Ophthalmic Solution Pharmaceutical Formulations for Parenteral
https://www.pharmacompass.com/pharma-excipients/parenteral/ophthalmic-solution-parenteral/sorbitan-monooleate-excipient
General chat about tween-20 as a WB block and wash - Protein and Proteomics - BioForumGeneral chat about tween-20 as a WB block and wash - Protein and Proteomics - BioForum
General chat about tween-20 as a WB block and wash - posted in Protein and Proteomics: Hi, I was interested about the specific mechanism by which tween-20 works as a block and wash of western blot membranes, but unfortunately I couldnt find much on it except for one bulletin. This suggested the large size of tween-20 would make it useful for a block but also that its size is due to its large hydrophillic head so that doesnt quite make sense. As for its ability to...
http://www.protocol-online.org/forums/topic/28216-general-chat-about-tween-20-as-a-wb-block-and-wash/
Sorbitan Ester Exporter, Manufacturer & Supplier, Sorbitan Ester India
JEEVIKA YUGCHEM PVT. LTD. - Exporter, Manufacturer & Supplier of Sorbitan Ester Sorbitan Ester,Sorbitan Monooleate,Sorbitan Monopalmitate,Sorbitan Trioleate,Sorbitan Monostearate,Sorbitan Sesquioleate,Sorbitan Monolaurate, India
http://www.jeevikayugchem.in/sorbitan-ester.html
MF59 and Squalene | Exploring VaccinesMF59 and Squalene | Exploring Vaccines
MF59 is an adjuvant which is a chemical used to increase the immune systems response to an antigen. MF59: MF59TM is a sub-micron oil-in-water emulsion of a squalene, polyoxyethylene sorbitan monooleate (TweenTM 80) and sorbitan trioleate. Squalene is a natural organic compound originally obtained from shark liver oil and a biochemical precursor…
https://explorevaccines.wordpress.com/2008/11/12/mf59-and-squalene/?referer=sphere_related_content/
Young Children Respond Well To Recommended Swine Flu Vaccine - RedorbitYoung Children Respond Well To Recommended Swine Flu Vaccine - Redorbit
Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: Open-label, randomized, parallel group, multicenter study. The first head to head study of the two H1N1 vaccines used in the UK during the recent pandemic finds that the adjuvanted split virus vaccine induced higher immune response rates in young children, but was associated with more reactions than the whole virus vaccine.. These data provide important information to guide immunisation policy in an influenza pandemic, say the researchers.. During the 2009-10 influenza A (H1N1) pandemic, children experienced pandemic A (H1N1) infections at four times the rate of adults and were more commonly admitted to hospital, making them a priority group for vaccination.. The Department of Health purchased two H1N1 vaccines for the national immunisation programme, an adjuvanted split virion vaccine derived from egg culture and a non-adjuvanted whole ...
http://www.redorbit.com/news/health/1872168/young_children_respond_well_to_recommended_swine_flu_vaccine/
Development of Complement assay - Optimization of buffers for a complement ELISA kit and development of a new homogenous...Development of Complement assay - Optimization of buffers for a complement ELISA kit and development of a new homogenous...
misc{7870232, abstract = {The complement system can be activated by three different pathways in the body. It is wanted to be able to detect deficiencies of these activation pathways and Bioporto A/S has acquired the commercial rights to a set of ELISA based assays. There is a need in these commercial assays for optimisation of dilution and wash buffers since the idea with the ELISA kit is to sell it as a ready-to-use kit and the dilution and wash buffer will be stored in small, concentrated volumes. In the concentrated volumes the reagent Tween-20 was a problem since it precipitated with CaCl2 in the buffers. The Tween-20 needed to be replaced and it was found that emulfogen had the same ability as Tween-20 to prevent unwanted binding in the wells without precipitating with CaCl2. Instead of 0,5% Tween-20 in the dilution buffer 0,1% emulfogen could be used and in the wash buffer 0,01% of emulfogen could be used instead of 0,05% Tween-20. Bioporto has also initiated to convert the complement ...
https://lup.lub.lu.se/student-papers/search/publication/7870232
polysorbate-20 | VWRpolysorbate-20 | VWR
Learn more about polysorbate-20. We enable science by offering product choice, services, process excellence and our people make it happen.
https://us.vwr.com/store/product/6904697/polysorbate-20
Polysorbate 80 risks - Vaccine Choice Canada
December, 2013. According to Wikipedia, Polysorbate 80 (brand names include Alkest, Canarcel and Tween, which is a registered trademark of ICI Americas, Inc.) is a nonionic surfactant, a compound which lowers the surface tension between two liquids or between a liquid and a solid…Surfactants may act as detergents, wetting agents, emulsifiers, foaming agents, and dispersants.. In a 2006 article, Sherri Tenpenny DO quotes from her book, Fowl! Bird Flu: Its Not What You Think, Chapter 8 of which describes how seasonal influenza vaccines are made. She informs that formaldehyde is used to kill the cultured influenza viruses, Triton X-100 is added to increase development of an antibody response, and Two other chemicals, tri-butylphosphate and polysorbate 80, then become part of the chemical soup of the vaccine. Tri-butylphosphate, a detergent and polysorbate 80, also known as Tween80™, is an emulsifier. Both are used to disrupt the surface of the virus, making the (H) and (N) antigens ...
https://vaccinechoicecanada.com/health-risks/anaphylaxis-allergies-asthma/polysorbate-80-risks-2/
Transport properties and aggregation phenomena of polyoxyethylene sorbitane monooleate (polysorbate 80) in pig gastrointestinal...Transport properties and aggregation phenomena of polyoxyethylene sorbitane monooleate (polysorbate 80) in pig gastrointestinal...
The aqueous environment in the gastrointestinal tract frequently requires solubilization of hydrophobic drug molecules in appropriate drug delivery vehicles. An effective uptake/absorption and systemic exposure of a drug molecule entails many processes, one being transport properties of the vehicles through the mucus layer. The mucus layer is a complex mixture of biological molecules. Among them, mucin is responsible of the gel properties of this layer. In this study, we have investigated the diffusion of polyoxyethylene sorbitane monooleate (polysorbate 80), a commonly used nonionic surfactant, in aqueous solution, in mucin solutions at 0.25 and 5 wt %, and in mucus. These measurements were done by using the pulsed field gradient spin echo nuclear magnetic resonance (PGSE-NMR) technique. We conclude that polysorbate 80 is a mixture of non-surface-active molecules that can diffuse freely through all the systems investigated and of surface-active molecules that form micellar structures with transport
http://publications.lib.chalmers.se/publication/80914-transport-properties-and-aggregation-phenomena-of-polyoxyethylene-sorbitane-monooleate-polysorbate-8
A Follow-up Study to Assess Long-term Immunogenicity and Safety of NicVAX/Placebo as an Aid to Smoking Cessation - Full Text...A Follow-up Study to Assess Long-term Immunogenicity and Safety of NicVAX/Placebo as an Aid to Smoking Cessation - Full Text...
This study will follow subjects that participated in the NicVAX phase III studies for a second year. These predecessor studies, Nabi-4514 (NCT#00836199) and Nabi-4515 (NCT#01102114) evaluate the efficacy and safety of 6 vaccinations of NicVAX or placebo as an aid to smoking cessation. The two phase III studies are one year in duration, and subjects who complete these studies are eligible to enroll in Nabi-4522. As the phase III studies are ongoing, subject assignment to NicVAX or placebo will remain masked. No intervention will be administered in Nabi-4522. Subjects will be followed for immunogenicity (anti-nicotine antibody level)and for safety ...
https://clinicaltrials.gov/ct2/show?term=nicvax&rank=2
Evaluation of Long-term Immunogenicity and Safety of a Human Papillomavirus (HPV) Vaccine in Healthy Female Subjects - Study...Evaluation of Long-term Immunogenicity and Safety of a Human Papillomavirus (HPV) Vaccine in Healthy Female Subjects - Study...
The only disclosure restriction on the PI is that the sponsor can review results communications prior to public release and can embargo communications regarding trial results for a period that is more than 60 days but less than or equal to 180 days. The sponsor cannot require changes to the communication and cannot extend the embargo ...
https://clinicaltrials.gov/ct2/show/results/NCT00947115
OmpT在Tween-20胶束中折叠的单分子研究
关键词: 单分子FRET, 荧光相关谱, OmpT折叠, Tween-20, DDM Abstract: The cell envelope of gram-negative bacteria consists of the outer membrane (OM), inner membrane (IM), and periplasm. The β-barrel outer membrane proteins (OMPs) embedded in the OM perform diverse and significant functions such as signaling, transporting, and proteolysis. The OMPs of gram-negative bacteria share similar folding pathways with that of mitochondria and chloroplasts. Therefore, the study of the OMP folding mechanism not only provides insights into antimicrobial drug design but also helps elucidate mitochondrial and chloroplast biogenesis. Most knowledge about OMP folding was obtained from ensemble experiments where OMPs were usually at micromolar concentrations and prone to aggregate, which is different from the physiological environment in the cells. Unlike ensemble techniques, single-molecule detection (SMD) can measure OMPs from nano- to picomolar concentrations and prevent aggregation. In this work, ...
http://www.whxb.pku.edu.cn/CN/10.3866/PKU.WHXB201806072
PEG-3 Sorbitan Stearate | Cosmetics InfoPEG-3 Sorbitan Stearate | Cosmetics Info
with Sorbitan Oleate reduces DNA repair following UV irradiation, but these data were not considered significant in view of the available carcinogenesis data. The Polysorbates were not oral or dermal carcinogens. Data on the cocarcinogenesis of certain Sorbitan Esters were positive, but only with high exposure levels and a high frequency of exposure, and the results lacked a dose-response. The Polysorbates also had antitumor activity in some studies. The Polysorbates had little potential for human skin irritation, sensitization, and phototoxicity in extensive clinical studies. Likewise, PEGs were nonsensitizers, but cases of kidney toxicity were observed in burn patients that were treated with PEG-based topical ointments. Overall, these data were considered an adequate basis for assessing the safety of the entire group of ingredients. The CIR Expert Panel concluded that these ingredients were safe for use in cosmetics at the levels in current use (not more than a 25% concentration) with the ...
http://www.cosmeticsinfo.org/ingredient/peg-3-sorbitan-stearate
Pandemic flu - NIHR EvidencePandemic flu - NIHR Evidence
Perinatal outcomes following maternal 2009/H1N1 infection: a national cohort study.. Pierce, M; Kurinczuk, J; Spark, P; Brocklehurst, P; Knight, M. BMJ 2011;342:d3214. Effectiveness of H1N1 vaccine for the prevention of pandemic influenza in Scotland, UK: a retrospective observational cohort study. Simpson CR, Ritchie LD, Robertson C, Sheikh A, McMenamin J. Lancet Infectious Diseases 2012;Volume 12, Issue 9, Pages 696 - 702, September 2012 doi:10.1016/S14. Predictors of immune response and reactogenicity to AS03B-adjuvanted split virion and non-adjuvanted whole virion H1N1 (2009) pandemic influenza vaccines. Andrews N J, Walker W T, Finn A, Heath P T, Collinson A, Pollard A J, Snape M, Faust S N, Waight P A, Hoschler K, Sheasby L, Waddington C, Kerridge S, Chalk J, John T, Fletcher M, Allen R, Fineman N, Wilkins S, Casey M, Michaelis L, Oeser C, Okiki I, Ladhani S, Miller E. Vaccine 2011;29(45):7913-9. Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion ...
https://evidence.nihr.ac.uk/collection/pandemic-flu/?wpfpaction=add&postid=39466
Polysorbate 80, Multi-Compendial, N.F., J.T.Baker™ 200mL; Narrow Mouth Amber Glass Bottle Polysorbate 80, Multi-Compendial, N.F...Polysorbate 80, Multi-Compendial, N.F., J.T.Baker™ 200mL; Narrow Mouth Amber Glass Bottle Polysorbate 80, Multi-Compendial, N.F...
Polysorbate 80, Multi-Compendial, N.F., J.T.Baker™ 200mL; Narrow Mouth Amber Glass Bottle Polysorbate 80, Multi-Compendial, N.F., J.T.Baker™ Surfactants...
https://www.fishersci.co.uk/shop/products/polysorbate-80-multi-compendial-n-f-j-t-baker-1/10554683
Performance of the Biocompatible Surfactant Tween 80, for the Formation of Microemulsions Suitable for New Pharmaceutical...Performance of the Biocompatible Surfactant Tween 80, for the Formation of Microemulsions Suitable for New Pharmaceutical...
Journal of Applied Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles related to all aspects of applied chemistry.
https://www.hindawi.com/journals/jac/2013/930356/
Nonionic Surfactants (Dodecyl Maltoside and Polysorbate 20) Effect on Light induced Aggregation and Conformational Changes of...Nonionic Surfactants (Dodecyl Maltoside and Polysorbate 20) Effect on Light induced Aggregation and Conformational Changes of...
Liquid protein formulations are prone to form aggregates. The effect of nonionic surfactants such as Polysorbate 20 (PS 20) and n-Dodecyl β-D-maltoside (DDM) on the prevention of aggregation and conformational changes of recombinant human IFNβ-1b (rhIFN β_1b) was explored. Polysorbate has been used in formulations of protein pharmaceuticals. There have been concerns about using PS 20 due to its residual peroxide content which may negatively affect protein efficacy. n-Dodecyl β-D-maltoside has been of interest and shown to be highly effective in prevention of aggregation. Fresh bulk of rhIFN β_1b was formulated using DDM or different concentrations of PS 20. Formulations were exposed to light stress condition according to the ICH guideline of Q1b. The overall conformational integrity of individual samples was characterized by a combination of Circular dichroism (CD), Fluorescence spectroscopy and RP_HPLC techniques.The CD spectrum depicting the conformational integrity of rhIFN β_1b showed 31.9%
http://ijpr.sbmu.ac.ir/article_1973.html
POLISZORBÁT 80 | Molar Chemicals Kft.POLISZORBÁT 80 | Molar Chemicals Kft.
POLYSORBATUM 80, POLYSORBATE 80, PEG-20-SZORBITÁN MONOOLEÁT, TWEEN® 80, POLYOXYETHYLENE-(20)-SORBITAN MONOOLEATE, POLIOXIETILÉN-(20)-SZORBITÁN MONOOLEÁT ...
https://www.molar.hu/index.php?page=product.molar&kod=09430-303-190&language=2&newmenu=1&print=1
Comparative immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and HPV-6/11/16/18 vaccine...Comparative immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and HPV-6/11/16/18 vaccine...
This observer-blind study (clinicaltrials.gov NCT01462357) compared the immunogenicity and safety of 2 doses of the HPV-16/18 AS04-adjuvanted vaccine (HPV-16/18(2D)) vs. 2 or 3 doses of the HPV-6/11/16/18 vaccine (HPV-6/11/16/18(2D) and HPV-6/11/16/18(3D)) in healthy girls aged 9-14 y. Girls were randomized (1:1:1) to receive HPV-16/18(2D) at months (M) 0,6 (N = 359), HPV-6/11/16/18(2D) at M0,6 (N = 358) or HPV-6/11/16/18(3D) at M0,2,6 (N = 358). The primary objective was non-inferiority/superiority of HPV-16/18 antibodies by ELISA for HPV-16/18(2D) vs. HPV-6/11/16/18(2D) at M7 in the according-to-protocol immunogenicity cohort (ATP-I) and total vaccinated cohort, respectively. Secondary objectives included non-inferiority/superiority of HPV-16/18(2D) vs. HPV-6/11/16/18(3D) at M7, non-inferiority/superiority at M12, HPV-16/18 neutralizing antibodies, frequencies of T-cells/B-cells, reactogenicity and safety. Antibody responses at M7 for HPV-16/18(2D) were superior to those for HPV-6/11/16/18(2D) ...
http://www.diva-portal.org/smash/record.jsf?pid=diva2:847496
Clinical Research on Using Elemene to Treat GliomaClinical Research on Using Elemene to Treat Glioma
Purpose: to explore the clinical effect of using elemene to treat gliomas. Methods: 49 patients with glioma were chosen, 16 treated with elemene only, 33 treated with elemene and chemotherapy drugs. Injection dose of elemene: for adults, 1000 mg/d, alternating injection in the carotid artery and peripheral veins, with 20 days as a course of treatment. Tumor size, clinical performance, survival time and side effects were evaluated and compared before and after the treatment. Results: after carotid artery and peripheral injection of elemene, the total efficiency was 46.94% (CR14.29%, PR 32.65%); tumor sizes decreased by 30.89% 55.97% on average; clinical symptoms showed different levels of improvement; the survival time of 32 patients were: ,1y, 7 patients, , 1y , 14 patients, , 2y, 6 patients, , 3y, 5 patients. The efficiency rate of using elemene alone was 37.5%, that using elemene and chemotherapy was 51.51%. Elemene did not cause bone marrow suppression, gastrointestinal reactions, and other ...
http://orient-hospital.com/ClinicalResearch.htm
Surfactants, Concentrates, Polysorbates, SiliconeSurfactants, Concentrates, Polysorbates, Silicone
Make your own buzz features a collection of surfactants, polysorbates, shampoo concetrate, concentrated soap making, liquid soap making. Order yours now!
https://www.makeyourown.buzz/surfactants-concentrates-polysorbates-silicone/
Bloggf rslur m na arins, okt ber 2011 - agny.blog.isBloggf rslur m na arins, okt ber 2011 - agny.blog.is
Read more atSuite101: Polysorbate80 Causes Infertility: An Emulsifier That Can Damage Your Reproductive Health ,Suite101.com http://joanna-karpasea-jones.suite101.com/polysorbate-80-causes-infertility-a60320#ixzz1agSIkfVR. Algengt bindiefni snyrtiv rum, b luefnum og jafnvel s, hefur sannast a vera frj semis ska valdur.. Polysarbate 80 (einnig ekkt semTween 80) er var veislu efni miklum fj lda vara, ar me al s, mj lkurv rum, vitam nt flum, kremum og smyrslum og lyfjav rum eins og t.d. b luefnum og krabbameins-varnar lyfjum. a er eitur og tti aldrei a vera ti , drukki , bori h e a sprauta manneskju!. Samkv mt ann lum Ofn mis, Asthma og n misfr i (Annals of Allergy, Asthma and Immunology, Volume95, Number 6,December 2005 , pp. 593-599(7). n verandi ing er, dulinn orsakavaldur br a ofn mis vi brag a og reyndist Polysorbate 80 vera orsakavaldurinn fyrir br aofn mis vi br g um af ekktum uppruna hj sj klingnum.. Ni urst ur: Polysorbate 80 er allsta ar n l gt ar sem leysandi efni geta veri a valda br ...
https://agny.blog.is/blog/agny/month/2011/10/
Shaving Cream Products Containing: POLYSORBATE-60 || Skin Deep® Cosmetics Database | EWGShaving Cream Products Containing: POLYSORBATE-60 || Skin Deep® Cosmetics Database | EWG
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
http://www.ewg.org/skindeep/browse.php?ingred06=705139&atatime=100&category=shaving_cream&ingred06=705139&showmore=products&atatime=50
Anti-itch/rash Cream Products Containing: POLYSORBATE-60 || Skin Deep® Cosmetics Database | EWGAnti-itch/rash Cream Products Containing: POLYSORBATE-60 || Skin Deep® Cosmetics Database | EWG
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
http://www.ewg.org/skindeep/browse.php?ingred06=705139&atatime=100&category=anti-itch%3B%3Brash_cream&ingred06=705139&showmore=products&start=0&order=webscore+DESC
Sorbitan, (Z)-9-octadecenoate (2:3) - Registration Dossier - ECHASorbitan, (Z)-9-octadecenoate (2:3) - Registration Dossier - ECHA
The PBT Assessment for Sorbitan, (Z)-9-octadecenoate (2:3) (CAS No. 8007-43-0) is based on the criteria set out in the Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment (ECHA, 2012). Persistence The read-across substancesanhydro-D-glucitol trioleate (CAS No. 26266-58-0)is readily biodegradable according to OECD 301 B (84.5% (CO2 evolution) after 28 days). Thus, Sorbitan, (Z)-9-octadecenoate (2:3) (CAS No. 8007-43-0) does not meet the screening criterion for persistency and it is not considered to be P or vP. Bioaccumulation Due to the low water solubility, rapid environmental biodegradation and metabolism via enzymatic hydrolysis of the Sorbitan esters category members, a relevant uptake and bioaccumulation in aquatic organisms is not expected. Enzymatic breakdown will initially lead to the free fatty acid and D-glucitol. From literature it is well known, that these hydrolysis products will be metabolised and excreted in fish effectively ...
https://echa.europa.eu/registration-dossier/-/registered-dossier/13736/2/3
Polysorbate 20 - Tween 20 - Redoka - Industrial Solvents and Cleaning Solutions
Buy Polysorbate 20 from £3.00/L from 500ml packs to 200L with no minimum order volumes. Available from Huddersfield/Holmfirth HD9.
https://www.redoka.co.uk/product/polysorbate-80-tween-820/
Griffin:Membrane Stripping and Reprobing - OpenWetWareGriffin:Membrane Stripping and Reprobing - OpenWetWare
II) Wash the membrane twice for 10 minutes each, at room temperature, in 1x TBS, 0.05% Tween-20. Use a large volume (10-20 ml) of buffer for each wash. III) Block the membrane for 1 hour at room temperature, or overnight at 4°C, in 1x TBS, 5% milk, 0.05% Tween-20. Comments: The western blotting procedures are the same for PVDF or nitrocellulose, however the handling of these membranes are different prior to- and during- transfer of proteins from the SDS-PAGE gel to the membrane. Nitrocellulose exhibits the highest sensitivity with very low backgrounds in all transfers, especially in protein blotting. Unlike PVDF, nitrocellulose wets out naturally, does not require methanol, and will not turn hydrophobic during the transfer process. Nitrocellulose is very easily blocked and does not need the many blocking steps required with PVDF. Protocols for Western Blotting with PVDF and Nitrocellulose are the same with a few exceptions. PVDF is hydrophobic and therefore should be prewet in methanol before ...
https://openwetware.org/wiki/?title=Griffin:Membrane_Stripping_and_Reprobing&oldid=244070
Enhance A.C.E. Treatment
The skin regenerates itself throughout epidermis and dermis for thicker and elastic skin. This will help reduce wrinkles and lines. The skin becomes more elastic, fresh, and enriched.. Cold processed Retinol in cream formulations is stable for at least one year, and the shelf life can be extended with Chelating agents, light protected sealed packaging like glass or aluminum. Anhydrous compositions increase shelf life and potency and hence are even more preferable.. Retinol 50P (Pharmaceutical) is a 50% Retinol in Tween-20. Retinol 50C (Cosmetic) is a 50% Retinol in Tween-20. Stabilized with cyclodextrins, liposomes, and with other vitamins is not desirable since their bio-availability gets lowered.. Enhance A.C.E. Treatment is a Retinol booster that helps accelerate cell turnover quickly while making the skin more elastic and enriched. This Treatment can be combined with other treatment modalities to give a more effective anti-aging treatment. With the help of synergistic Vitamin C & E ...
http://www.halecosmeceuticals.com/enhance-a-c-e-treatment/
Effect of Hydrophobic Chain Length on the Interfacial Dilational Rheological Properties of Polyoxyethylene Sorbitan Fatty Acid...
Abstract: The dilational rheological properties of a series of polyoxyethylene sorbitan fatty acid surfactants (TweenX) at the decane/water interface have been investigated using the drop shape analysis method. The experiment results showed that larger quantities of the Tween20 molecules with shorter hydrophobic chain lengths were adsorbed at the interface because they could arrange more closely. Tween40 and Tween60 molecules had similaractual cross-sectional areas, which meant that their interfacial tensions were also similar at the critical micelle concentration (γcmc). Furthermore, when the bulk concentration exceeded the critical micelle concentration (cmc), the modulus and elasticity of Tween20 were larger than those of Tween40 and Tween60. When the hydrophobic alkyl chain of TweenX reached a certain length, the interfacial film properties of TweenX affected by the hydrophobic chain length decreased, which led to similar dilational parameters.. Key words: Polyoxyethylene sorbitan fatty ...
http://www.whxb.pku.edu.cn/EN/abstract/abstract28966.shtml
China and Global Influenza Vaccine (Split Virion),Inactivated Industry Research Report 2014: ResearchMozChina and Global Influenza Vaccine (Split Virion),Inactivated Industry Research Report 2014: ResearchMoz
The report firstly introduced Influenza Vaccine (Split Virion),Inactivated basic information included Influenza Vaccine (Split Virion),Inactivated definition classification application industry chain structure industry overview; international market analysis, China domestic market analysis, Macroeconomic environment and economic situation analysis and influence, Influenza Vaccine (Split Virion),Inactivated industry policy and plan, Influenza Vaccine (Split Virion),Inactivated product specification, manufacturing process, product cost structure etc. then statistics Global and China key manufacturers Influenza Vaccine (Split Virion),Inactivated capacity production cost price profit production value gross margin etc details information, at the same time, statistics these manufacturers Influenza Vaccine (Split Virion),Inactivated products customers application capacity market position company contact information etc company related information, then collect all these manufacturers data and listed ...
https://pitchengine.com/pitches/5b60f32d-234c-4539-b43e-b9c5e6bd6d47
FDA Fast-Tracks Adjuvanted Influenza Vaccine - NVIC NewsletterFDA Fast-Tracks Adjuvanted Influenza Vaccine - NVIC Newsletter
On Sept. 15, 2015 FDA advisors voted to fast-track MF59 adjuvanted influenza vaccine, despite safety concerns and the higher number of adverse reactions to Fluad vaccine.
http://www.nvic.org/nvic-vaccine-news/september-2015/fda-fast-tracks-adjuvanted-influenza-vaccines.aspx
Patente US5976555 - Topical oil-in-water emulsions containing retinoids - Google PatentesPatente US5976555 - Topical oil-in-water emulsions containing retinoids - Google Patentes
Skin care compositions comprising an oil-in-water emulsion base containing retinoids and possessing good physical and chemical stability. More particularly, said skin care compositions contain (a) an emulsifier system selected from the group consisting of: (i) a mixture of glyceryl stearate and polyethylene glycol 100 stearate; (ii) cetearyl alcohol and cetearyl glucoside; (iii) a mixture of a polyethylene glycol ethers of stearyl alcohol; and (iv) a mixture of sorbitan stearate and polysorbate 60; (b) a co-emulsifier selected from the group consisting of cetyl alcohol, stearyl alcohol and mixtures thereof; (c) an oil phase present in the amount of from about 5 to about 20 percent by weight of the total emulsion composition which contains (i) a light, dry absorbable oil and (ii) substantive, emollient oils or waxes, wherein the light, dry absorbable oil and the substantive oil or wax are present in a ratio of from about 1:3 for about 10:1.
http://www.google.es/patents/US5976555
Tween-40,physical properties,suppliers,CAS,MSDS,structure,Molecular Formula, Molecular Weight ,Solubility,boiling point,...Tween-40,physical properties,suppliers,CAS,MSDS,structure,Molecular Formula, Molecular Weight ,Solubility,boiling point,...
Tween-40,physical properties,suppliers,CAS,MSDS,structure,Molecular Formula, Molecular Weight ,Solubility,boiling point, melting point
http://www.hellochem.com/En/xz/xz8/72298jcoyc.htm
What Is Polysorbate 60? | Healthy LivingWhat Is Polysorbate 60? | Healthy Living
Members of the polysorbate family aid in the combination of ingredients that are usually insoluble. Due to the prevalence of water and oil in cosmetic products, polysorbates are extensively used. They also reduce the surface tension of creams and liquids, which aids in the process of emulsifying. Polysorbate 60 is used in numerous cosmetic products, including shampoos, skin softeners, scented powders, makeup bases and foundations, exfoliants, sunless tanners and anti-aging creams. ...
https://healthyliving.azcentral.com/what-is-polysorbate-60-12290551.html
Palm Kernel Oil Extract Machine Manufacturer‏Palm Kernel Oil Extract Machine Manufacturer‏
About Palm Kernel Oil Extract Machine is an essential process for a complete Seed Hydraulic Press Machine because there are still some impurities such as phospholipids,Hydraulic Oil Press, .Palm Kernel Oil Extract Machine China Seed Oil Extraction Hydraulic Press Machine 50-120kg/H, Find details about China Hydraulic Oil Press Machine, Seed Hydraulic Press Machine from Seed Oil Extraction Hydraulic Press Machine 50-120kg/H
https://www.evangelicaloutpost.com/supply-49651178-palm-kernel-oil-extract-machine.html
Allergic Contact Dermatitis From Sorbitans in Beer and Bread | MDedge DermatologyAllergic Contact Dermatitis From Sorbitans in Beer and Bread | MDedge Dermatology
Sorbitan sesquioleate (SSO), sorbitan monooleate (SMO), and related compounds are increasingly recognized contact allergens. Sorbitan sesquioleate and SMO are n
https://www.mdedge.com/dermatology/article/207509/contact-dermatitis/allergic-contact-dermatitis-sorbitans-beer-and-bread
Polysorbate - WikipediaPolysorbate - Wikipedia
The number 20 following the polyoxyethylene part refers to the total number of oxyethylene -(CH2CH2O)- groups found in the molecule. The number following the polysorbate part is related to the type of fatty acid associated with the polyoxyethylene sorbitan part of the molecule. Monolaurate is indicated by 20, monopalmitate is indicated by 40, monostearate by 60, and monooleate by 80.. ...
https://en.wikipedia.org/wiki/Polysorbate
Ethoxylation Process And Application - Industrial Professionals - Cheresources.com CommunityEthoxylation Process And Application - Industrial Professionals - Cheresources.com Community
Ethoxylation Process And Application - posted in Industrial Professionals: Ethoxylation process is based on the addition reaction of EO(Ethylene oxide) to chain starter(compounds containing an active hydrogen atom), such as C12~C15 Fatty alcohol, Nonyl Phenol, Glycol(DEG or TEG), Castor oil, Sorbitan Monooleate and Tallow Amine. These reactions occur in the liquid phase and the addition of one mol EO to the chain starter will produces new primary OH groups. And, these groupds will react wi...
http://www.cheresources.com/invision/topic/10598-ethoxylation-process-and-application/
β-elemene inhibits the proliferation of T24 bladder carcinoma cells through upregulation of the expression of Smad4β-elemene inhibits the proliferation of T24 bladder carcinoma cells through upregulation of the expression of Smad4
β-elemene, a non-cytotoxic antitumor reagent, inhibits the growth, proliferation and DNA synthesis of multiple types of malignant cells, resulting in the apoptosis or suppressed vascularization of tumors. β-elemene is also able to enhance the immunogenicity of the tumor cells and ameliorate systematic cellular immunity in the tumor‑bearing body. Moreover, β-elemene has the advantages of high efficiency, safety and low possibility of drug tolerance over other antitumor agents used in antitumor treatment. Therefore, β-elemene has great potential in clinical applications. However, the mechanism of β-elemene antitumor activity is largely unknown. The aim of this study was to investigate whether β-elemene is able to repress the proliferation of T24 bladder carcinoma cells through regulation of the expression of the tumor suppressor gene, Smad4. Results of a methylthiazolyl tetrazolium (MTT) assay indicated that the proliferation of T24 cells was repressed by β-elemene in a time- and ...
https://www.spandidos-publications.com/10.3892/mmr.2012.1206/abstract
Events - HomeEvents - Home
The course provides an overview of state-of-the-art adjuvant systems and addresses the preclinical and clinical development of adjuvanted vaccines. It combines interactive theoretical parts (lectures and discussion rounds) with practical parts where participants work on different thematic case studies. Invited trainers will present the various adjuvant systems, such as Aluminum salts, Oil-in-Water emulsions, Water-in-Oil emulsions, Liposomes, PLGA particles, Virosomes, QS21, TLR ligands, as well as aspects of preclinical and clinical development of adjuvanted vaccines.For the practical parts, participants will be split into smaller groups. Each group will work on one case study, facilitated by a trainer. The trainer will introduce the case study, provide background information, and explain the tasks and questions for the group work. Following this introduction, each group will work independently on their case study for a given time and will prepare a summary of the case that will be presented to ...
https://www.enova-adjuvant.eu/events/
Immunogenicity and Safety Study of GSK Biologicals Trivalent Split Virion Influenza Vaccine (GSK1536489A) Fluviral (2012/2013...Immunogenicity and Safety Study of GSK Biologicals Trivalent Split Virion Influenza Vaccine (GSK1536489A) Fluviral (2012/2013...
This trial will investigate the pharmacodynamics and tolerability of split virion influenza vaccine (2012/2013 season) [Fluviral; GlaxoSmithKline] for the
http://adisinsight.springer.com/trials/700219529?error=cookies_not_supported&code=13c8421c-168d-4c36-b035-efef698e84f7
Polysorbate 80 Food Additive, Gut Bacteria, and Inflammation | HealDove
Polysorbate 80 is an emulsifier that is added to many foods. Evidence suggests that it may affect bacteria in the intestine and cause gut inflammation.
https://healdove.com/digestion/Polysorbate-80-Food-Additive-Inflammation-and-Health-Problems
POLYSORBATE 80 Cosmetic Ingredient (INCI)POLYSORBATE 80 Cosmetic Ingredient (INCI)
POLYSORBATE 80 ingredient for cosmetics formulations - find latest products launched and their applications in relevant industry news and technical articles
https://cosmetics.specialchem.com/inci/polysorbate-80/s-kolb?id=10785
2019 AAPS PharmSci 3602019 AAPS PharmSci 360
Methods: HME technique was used to prepare the SLN. The preparation involved 2 main steps; first, the formulation of a suspension by pumping the lipid and drug into the barrel and second was size reduction of the pre-suspension to obtain the nanoparticles (Figure 1). A modified screw configuration was used for the extrusion process. All the lipids used in the study were reported to be safe, biocompatible and biodegradable. The Itraconazole and the lipid (Compritol® 888 ATO/Precirol® ATO 5) was uniformly mixed and introduced into the barrel using the volumetric feeder. The surfactant (Tween® 80) was injected in the barrel using the peristaltic pump. The feeding rates of a volumetric feeder and peristaltic pump were optimized. The pre-suspension obtained was subjected to sonication for size reduction. The prepared formulation was assessed for particle size analysis, zeta potential, viscosity, entrapment efficiency, drug content, in vitro drug release, Transmission Electron Microscopy and ...
https://www.eventscribe.com/2019/PharmSci360/fsPopup.asp?efp=SUlFUEhHSFQ4MDkx&PosterID=234520&rnd=0.1709156&mode=posterinfo
Analytical Chemiluminescence/Micellar enhancement - Wikibooks, open books for an open worldAnalytical Chemiluminescence/Micellar enhancement - Wikibooks, open books for an open world
Well-defined mechanistic principles have emerged to rationalize micellar enhancement of chemiluminescence. The review of Lin and Yamada[1] focuses on how micelles may be used to improve chemiluminescence signals by changes that affect the reaction rate. These occur in the microenvironment (i.e. polarity, viscosity and/or acidity, etc.), in the chemical and photophysical pathway and in the solubilization, concentration and organization of the solute/reactant. We shall now use these principles as a framework for discussing this work and it will become clear that they are highly inter-related rather than mutually exclusive.[2]. There follow examples of micellar enhancement which have been explained by changes in the microenvironment. In the interaction of sulfite groups in drugs with dissolved oxygen in presence of acidic rhodamine 6G, the surfactant Tween 60 can enhance chemiluminescence by 200%, attributable to a microenvironment that leads to an increase in the fluorescence quantum yield of ...
https://en.m.wikibooks.org/wiki/Analytical_Chemiluminescence/Micellar_enhancement
Sorbitan Mono Stearate Manufacturer,Sorbitan Mono Stearate SupplierSorbitan Mono Stearate Manufacturer,Sorbitan Mono Stearate Supplier
SHREEJI PHARMA from Gujarat, India is a manufacturer, supplier, wholesaler and exporter of Sorbitan Mono Stearate at reasonable price.
https://www.shreejipharmainternational.com/sorbitan-mono-stearate-2849977.html
Patent US4002579 - Detergent composition - Google PatentsPatent US4002579 - Detergent composition - Google Patents
A detergent composition comprising as essential components (A) 5 - 50 parts by weight of a surfactant component consisting of a mixture of (1) 5 - 95% by weight of a water-soluble polyoxyethylene sorbitan fatty acid monoester and (2) 95 - 5% by weight of a fatty acid alkylolamide, and (B) 1 - 50 parts by weight of an organic acid salt having a chelating ability.
http://www.google.com.au/patents/US4002579
Are nanodispersions able to dehydrate the skin? - question & answerAre nanodispersions able to dehydrate the skin? - question & answer
With exception of the biodegradable liquid nanoparticles, all nanoparticles smaller than 100 nanometer (nm) have to be indicated as nanomaterial. The alcohol contents of nanodispersal sera and active agent concentrates often are supposed to have dehydrating effects. Since concentrations are low and the evaporation rate high, alcohol is insignificant in this context. Due to the presence of alcohol however no allergenic preservatives are required. Washout effects, by contrast, are caused by the tensidic components used in combination with nanocrystals. They can be identified in the INCI by denominations as for instance polysorbate 20, polysorbate 80, caprylyl/capryl glucoside, coco-glucoside, lauryl glucoside and decyl glucoside. They are polyethylene glycols (PEG) and sugar tensides which also are components of cleansing gels („rinse-off preparations). Washout effect means that the emulsifiers or tensides contained in skin care products (leave-on preparations) virtually leach out the skin. ...
https://dermaviduals.de/english/skin-topics/question-answer/are-nanodispersions-able-to-dehydrate-the-skin.html
Sorbitan sesquioleate nonionic surfactant | Sigma-AldrichSorbitan sesquioleate nonionic surfactant | Sigma-Aldrich
Sigma-Aldrich offers Sigma-S3386, Sorbitan sesquioleate for your research needs. Find product specific information including CAS, MSDS, protocols and references.
https://www.sigmaaldrich.com/catalog/product/sigma/s3386?lang=en®ion=US
Data CitationsHe X, Zhuo X-T, Gao Con, Bai R, Ye X-Y, Xie T | Emerging Understanding of Bcl-2 BiologyData CitationsHe X, Zhuo X-T, Gao Con, Bai R, Ye X-Y, Xie T | Emerging Understanding of Bcl-2 Biology
Data CitationsHe X, Zhuo X-T, Gao Con, Bai R, Ye X-Y, Xie T. provides quick access to multiple oxidative -elemene derivatives in one stage and represents the first adjustments on cyclohexyl band of -elemene. It really is expected to start the chance for long term derivatization on cyclohexyl band of -elemene. The brand new compounds obtained above showed better anti-proliferation activities than -elemene itself on several cancer cell lines. Among them, compound 17 shows the best activity in antiproliferation assays of A549 and U-87MG cell lines. Y. H. Chen et C. Ling belongs to one of the important traditional Chinese medicines (TCM), and has been used to treat cancer and various diseases for nearly a thousand years [1C4]. The essential oil obtained from this plant is called elemene extracts, which contain at least four sesquiterpene isomers, namely -elemene, -elemene (1), -elemene, and -elemene [5C7]. In 2008, the State Food and Drug Administration Lumicitabine of China approved the uses of ...
http://bcl-2-protein.com/%EF%BB%BFdata-citationshe-x-zhuo-x-t-gao-con-bai-r-ye-x-y-xie-t/
Sanofi and GSK initiate new Phase 2 study of their adjuvanted recombinant protein-based COVID-19 vaccine candidateSanofi and GSK initiate new Phase 2 study of their adjuvanted recombinant protein-based COVID-19 vaccine candidate
Sanofi and GSK initiate new Phase 2 study of their adjuvanted recombinant protein-based COVID-19 vaccine candidate New Phase 2 study assesses potential for refined antigen formulation to achieve optimal immune response, including in older adultsIf results are positive, Phase 3 study to start in Q2 2021, with vaccine expected to be available in Q4 2021 In parallel, development work on new SARS-CoV-2 variants underway PARIS and LONDON - February 22, 2021 - Sanofi and GSK announced today the initiation of a new Phase 2 study with 720 volunteers aged 18 and over to select the most appropriate antigen dosage for Phase 3 evaluation of their adjuvanted recombinant protein COVID-19 vaccine candidate.
https://uk.finance.yahoo.com/news/sanofi-gsk-initiate-phase-2-104000714.html
Tiempo de despertar inmediato e intermedio al comparar dos técnicas anestésicas: ATIV (propofol sufentanilo) versus AGB ...
Comparada con la anestesia general inhalatoria (AGI), a la anestesia total intravenosa (ATIV) se le han atribuido ventajas como son el despertar m s predecible, una recuperaci n m s temprana del estado de conciencia y de funciones psicomotoras y la baja incidencia de n usea y v mito postoperatorio. Comparamos los tiempos de despertar con el uso de dos t cnicas anest sicas AGB y ATIV usando propofol y sevoflorano, en dosis equipotentes. REFERENCIAS (EN ESTE ART CULO) ...
https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=50351
Samsung ATIV S Screensavers Free DownloadSamsung ATIV S Screensavers Free Download
Samsung ATIV S screensavers free download for your mobile. Samsung ATIV S screensaver download and thousands of latest free screensavers for SamsungATIVS cell phone.
http://www.mobileheart.com/cell-phone-screensavers/3209-Samsung-ATIV-S-Screensavers.aspx
Palm kernel oilPalm kernel oil
The primary dietary suggestion to reduce cardiovascular disease (CVD) at this time is to reduce saturated fatty acids (SFAs.) SFAs raise both total and LDL cholesterol. This article is about what to use to replace SFAs for energy. Substitution of SFAs with polyunsaturated fatty acids (PUFAs) results in a reduction of risk of CVD to […]. View Post ...
https://www.rainbow.coop/nutritional-library/food/palm-kernel-oil/
Practical Fragments: December 2013Practical Fragments: December 2013
But experimentalists should not get too cocky: the next paper, by Jamie Simpson and collaborators at Monash University, describes some of the things that can go wrong. An STD NMR screen of the antimicrobial target ketopantoate reductase (KPR) using the same Maybridge library of 500 compounds revealed 196 hits! The 47 with the strongest STD signals were then tested in a 1H/15N-HSQC NMR assay, leading to 14 hits, of which 4 gave measurable IC50 values in an enzymatic assay. Unfortunately, follow-up SAR was disappointing, and subsequent experiments revealed that aggregation was to blame: when the biochemical experiments were rerun in the presence of 0.01% Tween-20, only a single fragment gave a measurable IC50 value. The researchers redid their STD-NMR screen in the presence of detergent, resulting in 71 hits, all of which were tested in the biochemical screen. This led to the identification of a new (and fairly potent) hit that had previously been missed. This nicely illustrates the fact that ...
http://practicalfragments.blogspot.com/2013_12_01_archive.html
background on 2D western blotbackground on 2D western blot
Hi Will! All I can offer is that our system with Western blotting on NC works consistently. I use 5% skim milk in TBST buffer (10 mM Tris-HCl, pH 8.0; 0.15 M NaCl; 0.1% Tween-20) to block, and also use the blocking buffer to dilute the primary and secondary antibody, and for the washing steps between. I use a chemiluminescence detection system, and found at first an unspecific streak on my blot. This turned out to be me applying the strepavidin-AP directly over my blot (after incubation with the biotinylated secondary antibody) instead of to the incubation solution, thus removing my blocking and getting this signature streak *grin*. Hope you iron out your problem soon. ;-) Araluen Will Chiu ,will.chiu at auckland.ac.nz, wrote in message news:20010928103151.16882.qmail at ww02.jatek.com... , Dear All , , I have been experiencing intense spotty backgrounds on my 2D western blot , probed with sera using NC membrane. A switch to PVDF membrane managed to rid , of the spots but background noise ...
http://www.bio.net/bionet/mm/methods/2001-October/090619.html
Magnetic beads - Protein and ProteomicsMagnetic beads - Protein and Proteomics
It worked well, and wasnt hard. Im at home and dont have the protocol in front of me, but it was essentally equilibrate (wash) the beads (50 ul) in 700 ul binding/wash buffer (50 mM Na phosphate buffer, pH 8.0, 500 mM NaCl, and some Tween-20 -- 0.01% perhaps?), resuspend the beads in 600 ul binding/wash buffer, then add your sample (100 ul) to the beads. Bind the sample by incubating (RT or 4C or 37C depending on your application) for 30 minutes while mixing (end-over-end). Pull the beads down with a magnet, pipette off the supernatant and wash (resuspend the beads in 700 ul binding/wash buffer, pull them back down with a magnet, decant the supe) four times.. ...
http://www.protocol-online.org/biology-forums/posts/12894.html
ECL Western Blotting, need helpECL Western Blotting, need help
On 31 Jul 1997 00:19:25 GMT, yankiwski at aol.com (Yankiwski) wrote: ,Hi, , ,Ive been trying to detect a protein transferred to Immobilon membranes, ,and have had poor results. On one attempt I got lots of bands with high ,background levels and nonspecific binding. Stripping the membrane and ,probing again with lower Ab dilutions resulted in a blank film. Ive ,tried a variety of Ab dilutions and incubation times, without better ,results. Is there a subtlety in the technique that Im missing? The ECL ,detection reagents themselves are working properly, but perhaps my ,stripping conditions (30 min. @ 65 C) were too harsh? The only other ,reagents I use are 5% non-fat dry milk in TBS w/ NaN3 to block, and ,TBS/0.1% Tween-20 for washes. (The Abs themselves are diluted in non-fat ,dry milk in TBS). Any suggestions on improving my results and on the ECL ,technique in general would be appreciated, as I am new to this method. , ,Thanks, ,Victor Dear Victor! 1. Are you shure that your antibody is ...
http://www.bio.net/bionet/mm/methods/1997-July/059826.html
Vezina Protocols - IHCVezina Protocols - IHC
Solutions. Day 1. PBSTw: 1X PBS containing 0.1% Tween-20 and 0.2mM sodium azide. Pass through 0.2µm filter to remove insoluble material/contaminants.. 6% H2O2: 1mL 30% H2O2 per 4mL PBS. Proteinase K: 0.25µL 20mg/mL proteinase K per 1mL PBSTw. Post-fix: 8µL 25% glutaraldehyde per 1mL 4% PFA. Prehybridization solution. ...
http://www.gudmap.org/Research/Protocols/Vezina/ISH_VibMicro.html
Polysorbate 80: A Risky Vaccine IngredientPolysorbate 80: A Risky Vaccine Ingredient
The recent public conversation about the safety of vaccine ingredients has centered primarily around mercury (thimerosal), aluminum and formaldehyde. However,
http://healthimpactnews.com/2016/polysorbate-80-a-risky-vaccine-ingredient/
Preventing Tween Behavior Problems | ParentingPreventing Tween Behavior Problems | Parenting
How to keep your tween away from smoking, drinking, sexting and other tween behavior problems. Plus, learn the 8 discipline mistakes parents make
http://www.parenting.com/article/preventing-tween-behavior-problems?page=0,5
Natural Health News: Polysorbate 80 - One toxic ingredient in vaccinesNatural Health News: Polysorbate 80 - One toxic ingredient in vaccines
According to the MSDS sheet at Science lab.com, section 11: Toxicological Information, it was tested for inhalation and ingestion and was shown to be slightly hazardous on skin contact, ingestion and inhalation. however these are minor compared to other potential side effects of its use especially in an intravenous or immunologic setting. In the same section of toxicological information it states that it may cause reproductive effects, it may cause cancer, and may be a mutagenic, (change the genetics), in animals but this is followed up with the statement, no human data found. Well, unless they use people as lab rats, they wont find this data until it is used on humans to an extent to present this data ...
http://naturalhealthnews.blogspot.com/2011/08/polysorbate-80-one-toxic-ingredient-in.html
Search resultsSearch results
DETERMINACION DE LA DEMANDA QUIMICA DE OXIGENO Y DE LA OXIDABILIDAD AL PERMANGANATO DE DISPERSANTES NO IONICOS. I. DERIVADOS DEL SORBITAN. SERIES TWEEN Y SPAN. = DETERMINATION DE LA DEMANDE CHIMIQUE EN OXYGENE ET DE LOXYDABILITE AU PERMANGANATE DE DISPERSANTS NON IONIQUES. I. DERIVES DU SORBITAN. SERIES TWEEN ET SPANBERGUEIRO JR; BAO M; CASARES JJ et al.1977; ; ION; ESP.; DA. 1977; VOL. 37; NO 432; PP. 341-343; ABS. ANGL.; BIBL. 16 REF.Article ...
https://pascal-francis.inist.fr/vibad/index.php?action=search&lang=en&terms=%22NON+IONIC+SURFACTANT%22&index=kw
Benchmark Results: Photoshop, iTunes, And WinRAR - Samsungs ATIV Smart PC 500T: An Atom-Based Windows 8 Tablet | Toms HardwareBenchmark Results: Photoshop, iTunes, And WinRAR - Samsungs ATIV Smart PC 500T: An Atom-Based Windows 8 Tablet | Toms Hardware
Were able to use one set of tests to compare Samsungs ATIV Smart PC 500T against tablets. But when you drop the Atom-powered device into its docking station, it becomes more of a netbook or lightweight notebook. So, how does it perform in that role? Again, the full version of Windows 8 gives us access to our usual benchmark suite.
https://www.tomshardware.com/uk/reviews/ativ-smart-pc-500t-windows-8-atom,3360-8.html
INTERROS: Press Center: newsINTERROS: Press Center: news
In July 2018, Petrovax Pharm received Marketing Authorization No. LP-004951 for Grippol® Quadrivalent, a 4-valent inactivated subunit adjuvanted vaccine designed for prevention of influenza. It is the most advanced flu vaccine in the world that employs an antigen sparing technology and has a high preventive activity and safety ...
https://www.interros.ru/en/press/news/?tags=UNEXIM+Bank%2CPetrovax+Pharm%2Cquadrivalent+vaccine%2CRUIE%2CRussian+International+Olympic+University%2CCinema+Park
INTERROS: Press Center: newsINTERROS: Press Center: news
In July 2018, Petrovax Pharm received Marketing Authorization No. LP-004951 for Grippol® Quadrivalent, a 4-valent inactivated subunit adjuvanted vaccine designed for prevention of influenza. It is the most advanced flu vaccine in the world that employs an antigen sparing technology and has a high preventive activity and safety ...
https://www.interros.ru/en/press/news/?tags=Petrovax+Pharm%2CSustainable+tourism&%3BPAGEN_2=3&PAGEN_2=5
Pandas Paper Playtime: Tween CardPandas Paper Playtime: Tween Card
I said yesterday that I had a tween card to show today and I thought I ought to post before work for a change. The image was draw as a request by my brother-in-law. He enjoyed drawing it so much he has been drawing away ever since. Hopefully I will have more of his images to show soon. I have left the card fairly plain to show off the image ...
http://pandaspaperplaytime.blogspot.com/2010/02/tween-card.html
Everyday Mom Ideas: The Man Date with Dad; Normalizing Puberty For Anxious TweenEveryday Mom Ideas: The Man Date with Dad; Normalizing Puberty For Anxious Tween
has moved to a new address:. Everyday Mom Ideas: The Man Date with Dad; Normalizing Puberty For Anxious Tween Sorry for the inconvenience… Redirection provided by Blogger to WordPress Migration Service ...
http://www.everydaymomideas.com/2017/09/the-man-date-with-dad-normalizing.html
N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective...N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective...
Compounds and Administration Procedures. BCTC was synthesized according to known methods and was used in all experiments as its free base (molecular weight 372.89). Indomethacin (Sigma-Aldrich, St. Louis, MO) and BCTC were administered orally in 2% β-cyclodextrin (Sigma-Aldrich) by gastric gavage in a dose volume of 10 ml/kg b.wt. Gabapentin (Kemprotec, Middlesborough, UK) was dissolved in saline and administered via i.p. injection in a dose volume of 2 ml/kg. Capsaicin (Sigma-Aldrich) was used in all experiments as its free base. The procedure of Gilchrist et al. (1996) was used to dissolve the capsaicin. Briefly, 6 mg of capsaicin was first dissolved in 0.14 ml of polyoxyethylene (20) sorbitan mono-oleate (Tween 80) by gently heating the solution to approximately 70°C. The solution was then diluted with 1.86 ml of 0.9% sodium chloride using an ultrasonic bath, and passed through a 0.20-μm filter. The final concentration of the capsaicin solution was 3 μg/μl. Intraplantar injections of the ...
http://jpet.aspetjournals.org/content/306/1/387.long
Plus itPlus it
1. The parenteral administration of Tween 20 to several species of animals has been investigated. Injections of five per cent solutions subcutaneously and intramuscularly are well tolerated by the monkey. Intravenous injections produce transient depressor responses in all species of laboratory animals tested (except the dog) when given in small doses. Larger doses produce coma and death.. Tween 20 is hemolytic to red cells in concentrations of 100 mg. per cent within 90 minutes in vitro.. 2. Tweens 20, 40, 60 and 80 produce in the dog a deep and protracted fall in blood pressure.. 3. The depressor response appears to be due to the release of histamine or histamine-like substances which act upon the capillary bed.. 4. This allergic depressor response is not elicited in the rat, guinea pig, cat, rabbit, Macacus rhesus monkey, chicken or man.. 5. To 4 hospitalized patients 2 to 8 cc. of Tween 20, 5 per cent solution, has been given intravenously. There were no discernible deleterious ...
http://jpet.aspetjournals.org/content/93/2/188
What is known about binding in the presence of nonionic detergents? | NEBWhat is known about binding in the presence of nonionic detergents? | NEB
Some fusion proteins do not bind efficiently (, 5% binding) in the presence of 0.2% Triton X-100 or 0.25% Tween 20, while other fusions are unaffected. For one fusion that does not bind in 0.25% Tween 20, diluting the Tween to 0.05% restores about 80% of the binding ...
https://international.neb.com/faqs/2019/05/08/what-is-known-about-binding-in-the-presence-of-nonionic-detergents
PolysorbatePolysorbate
... 20 (polyoxyethylene (20) sorbitan monolaurate) Polysorbate 40 (polyoxyethylene (20) sorbitan monopalmitate) ... Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate) The number following the 'polysorbate' part is related to the type of ... Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are commonly used in oral and ... Polysorbates are oily liquids derived from ethoxylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Common ...
https://en.wikipedia.org/wiki/Polysorbate
Polysorbate 20Polysorbate 20
... is also used as wetting agent in rubber balers in the elastomer industry. Polysorbate 20 has been used as a ... Polysorbate 20 is used in many brands of baby wipes. Polysorbate 20 is used by philatelists to remove stamps from envelopes and ... Polysorbate 20 is used as a wetting agent in flavored mouth drops such as Ice Drops, helping to provide a spreading feeling to ... Polysorbate 20 (common commercial brand names include Kolliphor PS 20, Scattics, Alkest TW 20, Tween 20, and Kotilen-20) is a ...
https://en.wikipedia.org/wiki/Polysorbate_20
Polysorbate 80Polysorbate 80
Polysorbate 20, used as a wetting agent in mouth drops Polysorbate 40 Polysorbate 60, used as an emulsifier in powdered drink ... Polysorbate 80 is a surfactant and solubilizer used in a variety of oral and topical pharmaceutical products. Polysorbate 80 is ... Influenza vaccines contain 2.5 μg of polysorbate 80 per dose. Polysorbate 80 is found in many vaccines used in the United ... In the nomenclature of polysorbates, the numeric designation following polysorbate refers to the lipophilic group, in this case ...
https://en.wikipedia.org/wiki/Polysorbate_80
Sorbitan monopalmitateSorbitan monopalmitate
SMP is a polysorbate that is derived from the mixture of partial esters of sorbitol treated with palmitic acid. SMP is a ... It may be found in combination with polysorbates. It is used to modify crystallisation of fats. It is insoluble in water. Up to ... monohexadecanoate.Polysorbate 40". The UK Food Guide. "E 495: Sorbitane mono palmitate". FOOD-INFO. BELL Jr., JT (1959). " ...
https://en.wikipedia.org/wiki/Sorbitan_monopalmitate
Sorbitan tristearateSorbitan tristearate
Brand names for polysorbates include Alkest, Canarcel, and Span. The consistency of sorbitan tristearate is waxy; its color is ...
https://en.wikipedia.org/wiki/Sorbitan_tristearate
Zippy the PinheadZippy the Pinhead
He sometimes snacks on Polysorbate 80. Zippy's unpredictable behavior sometimes causes severe difficulty for others, but never ...
https://en.wikipedia.org/wiki/Zippy_the_Pinhead
Immunologic adjuvantImmunologic adjuvant
The third AS03 ingredient is polysorbate 80. Polysorbate 80 is also found in both the Oxford-AstraZeneca and Janssen COVID-19 ...
https://en.wikipedia.org/wiki/Immunologic_adjuvant
DocetaxelDocetaxel
... interacted little with erythrocytes and was unaffected by the polysorbate 80 in its storage medium. Polysorbate 80 ... 80 mg Taxotere is supplied identically but with 2.0 mL polysorbate 80 and 6.0 mL 13% ethanol in saline. The docetaxel and ... The solution is a clear brown-yellow containing 40 mg docetaxel and 1040 mg polysorbate 80 per mL. 20 mg Taxotere is ... The same grade, quality, and quantity of polysorbate 80 are present in the infusion solution of both formulations. The only ...
https://en.wikipedia.org/wiki/Docetaxel
SorbitanSorbitan
When used alone they produce stable water-in-oil emulsions but they are frequently used with a polysorbate in varying ... Sorbitan is primarily used in the production of surfactants such as polysorbates; which are important emulsifying agents, with ... Ethoxylated sorbitan esters are known as polysorbates (trade name: Tweens). They are an important class of emulsifiers used in ...
https://en.wikipedia.org/wiki/Sorbitan
Scooba (brand)Scooba (brand)
Polysorbate 20 and tetrapotassium EDTA were the primary ingredients. Some Scooba models could also use white vinegar or plain ...
https://en.wikipedia.org/wiki/Scooba_(brand)
Polyethylene glycolPolyethylene glycol
May 2019). "Immediate Hypersensitivity to Polyethylene Glycols and Polysorbates: More Common Than We Have Recognized". The ...
https://en.wikipedia.org/wiki/Polyethylene_glycol
EmulsionEmulsion
Common examples include emulsifying wax, polysorbate 20, and ceteareth 20. Sometimes the inner phase itself can act as an ...
https://en.wikipedia.org/wiki/Emulsion
Nanoparticles for drug delivery to the brainNanoparticles for drug delivery to the brain
Surfactants such as polysorbate 80, 20, 40, 60, and poloxamer 188, demonstrated positive drug delivery through the blood-brain ... Surface coating nanoparticles with surfactants such as polysorbate 80 or poloxamer 188 was shown to increase uptake of the drug ... It was encapsulated in polysorbate 80 coated nanoparticles and intravenously injected. This was a huge breakthrough in the ...
https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain
TBSTTBST
... a polysorbate-type nonionic surfactant). Polysorbate 20 is also known as Tween 20, a commercial brand name. It is a common ... In molecular biology, TBST (or TTBS) is a mixture of tris-buffered saline (TBS) (a buffer solution) and Polysorbate 20 ( ...
https://en.wikipedia.org/wiki/TBST
Shoe polishShoe polish
These include ammonia, morpholine and various ethoxylated surfactants such as polysorbate 80. The waxes are often some mixture ...
https://en.wikipedia.org/wiki/Shoe_polish
MRS agarMRS agar
Polysorbate 80 is a surfactant which assists in nutrient uptake by Lactobacilli. Magnesium sulfate and manganese sulfate ... polysorbate 80 (also known as Tween 80) 0.2% dipotassium hydrogen phosphate 0.2% triammonium citrate 0.02% magnesium sulfate ...
https://en.wikipedia.org/wiki/MRS_agar
Ice creamIce cream
Soy lecithin and polysorbate are two popular emulsifiers used for ice cream production. A mouse study in 2015 shows that two ... commonly used dietary emulsifiers carboxymethylcellulose (CMC) and polysorbate 80 (P80) can potentially cause inflammatory ...
https://en.wikipedia.org/wiki/Ice_cream
EthoxylationEthoxylation
Examples synthesized on an industrial scale include octyl phenol ethoxylate, polysorbate 80 and poloxamers. Ethoxylation is ...
https://en.wikipedia.org/wiki/Ethoxylation
Sorbic acidSorbic acid
Sorbitol Polysorbate Acids in wine Parasorbic acid Erich Lück, Martin Jager, Nico Raczek (2000). "Sorbic Acid". Ullmann's ...
https://en.wikipedia.org/wiki/Sorbic_acid
Phenotypic testing of mycobacteriaPhenotypic testing of mycobacteria
Polysorbate 80 hydrolysis A test for lipase using polysorbate 80 (polyoxyethylene sorbitan monooleate, a detergent). Certain ... The test solution also contains phenol red, which is stabilised by the polysorbate 80; when the latter 80 is hydrolysed, the ... polysorbate 80). Citrate Sole carbon source Egg medium Growth on Löwenstein-Jensen medium (LJ medium) L-Glutamate Sole carbon ...
https://en.wikipedia.org/wiki/Phenotypic_testing_of_mycobacteria
EvofosfamideEvofosfamide
The current drug product formulation is a sterile liquid containing ethanol, dimethylacetamide and polysorbate 80. For ... Diluted evofosfamide formulation (100 mg/mL evofosfamide, 70% ethanol, 25% dimethylacetamide and 5% polysorbate 80; diluted to ...
https://en.wikipedia.org/wiki/Evofosfamide
Food safetyFood safety
Same for polysorbate E 435: see 2012.0838 from Denmark, unauthorised polysorbates in coconut milk and, 2007.AIC from France. ...
https://en.wikipedia.org/wiki/Food_safety
Þórdís KristmundsdóttirÞórdís Kristmundsdóttir
Thorgeirsdóttir, T. O., Thormar, H., & Kristmundsdóttir, T. Effects of polysorbates on antiviral and antibacterial activity of ...
https://en.wikipedia.org/wiki/Þórdís_Kristmundsdóttir
Topical fluorideTopical fluoride
... preparation containing benzyl alcohol derivative, polysorbate 80 and propylene glycol should be used in ...
https://en.wikipedia.org/wiki/Topical_fluoride
Haloterrigena turkmenicaHaloterrigena turkmenica
Also according to Selim et al., H. turkmenica is also able to hydrolyze tweens 80 (a branded version of polysorbate 80), casein ...
https://en.wikipedia.org/wiki/Haloterrigena_turkmenica
Discovery and development of tubulin inhibitorsDiscovery and development of tubulin inhibitors
Poor water solubility of drugs which need to be dissolved in polyoxyethylated castor oil or polysorbate what cause ...
https://en.wikipedia.org/wiki/Discovery_and_development_of_tubulin_inhibitors
Sputnik V COVID-19 vaccineSputnik V COVID-19 vaccine
Tris (hydroxymethyl) aminomethane, sodium chloride, sucrose, magnesium chloride hexahydrate, Sodium EDTA, polysorbate 80, ... Polysorbate 80 Ethanol 95% Water No adjuvants and no other components or ingredients should be included in the vaccine. Large ...
https://en.wikipedia.org/wiki/Sputnik_V_COVID-19_vaccine
Scope (mouthwash)Scope (mouthwash)
Inactive ingredients of Scope Outlast are water, glycerin, polysorbate 80, sodium saccharin, sodium benzoate, benzoic acid, ...
https://en.wikipedia.org/wiki/Scope_(mouthwash)
Kluyveromyces marxianusKluyveromyces marxianus
In a Dalmau plate culture containing cornmeal agar and Polysorbate 80, K. marxianus forms a rudimentary to branched ...
https://en.wikipedia.org/wiki/Kluyveromyces_marxianus
Borate buffered salineBorate buffered saline
Additives such as [Polysorbate 20] and milk powder can be used to add to BBS's functionality as a washing buffer or blocking ...
https://en.wikipedia.org/wiki/Borate_buffered_saline
Tween 80 (Polysorbate) EMPROVE ESSENTIAL Ph Eur,JP,NF 9005-65-6Tween 80 (Polysorbate) EMPROVE ESSENTIAL Ph Eur,JP,NF 9005-65-6
Polysorbate 80; find SAFC-817061 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma- ... Polysorbate) EMPROVE® ESSENTIAL, Ph. Eur., JP, NF; CAS Number: 9005-65-6; Synonyms: TWEEN® 80,POE (20) sorbitan monooleate, ... Polysorbate 80 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting ... BSE/TSE Certificate for 817061 Tween® 80 (Polysorbate) EMPROVE® ESSENTIAL Ph Eur,JP,NF ...
https://www.sigmaaldrich.com/NO/en/product/mm/817061
Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear...Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear...
Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear ...
https://www.merck.com/publication/mechanistic-investigation-of-drug-supersaturation-in-the-presence-of-polysorbates-as-solubilizing-additives-by-solution-nuclear-magnetic-resonance-spectroscopy/
Polysorbate 80Polysorbate 80
... is a solubilizer, emulsifier, wetting agent, viscosity modifier, dispersing agent, and stabilizer. Use in bath ...
https://www.bathbodysupply.com/polysorbate-80-pa1602.htm
Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling | bioRxivProfiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling | bioRxiv
b) Structures of a generic phospholipid (a natural substrate), polysorbate-20 (PS-20) and polysorbate-80 (PS-80). All 3 ... 3 Polysorbate-80 (PS-80) and polysorbate-20 (PS-20) are the most widely used PSs in the biopharma industry.2-3 The degradation ... McShan, A. C., Kei, P., Ji, J. A., Kim, D. C., Wang, Y. J., Hydrolysis of Polysorbate 20 and 80 by a Range of Carboxylester ... Kishore, R. S., Kiese, S., Fischer, S., Pappenberger, A., Grauschopf, U., Mahler, H. C., The degradation of polysorbates 20 and ...
https://www.biorxiv.org/content/10.1101/2020.10.07.330076v1.full
Polysorbate Market Size USD 1,425.3 Mn by 2027 | CAGR of 4.7%Polysorbate Market Size USD 1,425.3 Mn by 2027 | CAGR of 4.7%
Polysorbate report classifies global market by share, product, type, usage, end-use, and region , Polysorbate Industry ... Polysorbate market size was valued at USD 1,015.0 Million in 2019 and is anticipated to reach USD 1,425.3 Million by 2027 ... Polysorbate 20. 9.2.2.2. Polysorbate 40. 9.2.2.3. Polysorbate 60. 9.2.2.4. Polysorbate 80. 9.2.3. Market By Usage, Market ... Polysorbate 20. 9.3.2.2. Polysorbate 40. 9.3.2.3. Polysorbate 60. 9.3.2.4. Polysorbate 80. 9.3.3. Market By Usage, Market ...
https://www.emergenresearch.com/amp/industry-report/polysorbate-market
Polysorbates - MexicoPolysorbates - Mexico
Oxiteno has a broad portfolio of Polysorbates with a low dioxane content ... Polysorbates act as humectants, solubilizers, and emulsifiers. Oxiteno has a broad portfolio of Polysorbates with a low dioxane ... Learn more about Polysorbates. For more technical information on each product, select the items of interest and request ... Polysorbates are produced through the ethoxylation of sorbitan esters, which are delivered through sorbitols reaction with ...
https://oxiteno.com/mx/en/portfolio/polysorbates/
Emulsifiers(NP,OP,OS,EL,AEO,Polysorbate...) from China Manufacturer, Manufactory, Factory and Supplier on ECVV.comEmulsifiers(NP,OP,OS,EL,AEO,Polysorbate...) from China Manufacturer, Manufactory, Factory and Supplier on ECVV.com
Polysorbate...) from China Manufacturer, Manufactory, Factory and Supplier - Zhejiang Huangma Chemical Industry Group, CO., Ltd ... Emulsifiers(NP,OP,OS,EL,AEO,Polysorbate...) Payment Terms: L/C, T/T(Bank Transfer) ...
https://www.ecvv.com/product/1469170.html
POLYSORBATE 80
Relative densities of Polysorbates 20 and 60 = about 1.10; Polysorbate 80 = about 1.08.Definition: Polysorbates are mixtures of ... Polysorbate 80 has not been found to be carcinogenic. Rats fed with diets containing up to 5% polysorbate 80 by volume for 12 ... Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. Polysorbate 80 is an excipient that ... In Polysorbate 60 the fatty acid is stearic acidwhich may contain other fatty acids, especially palmitic acid. In Polysorbate ...
https://drugs.ncats.io/drug/6OZP39ZG8H
HPLC Retention of Polysorbate on Primesep D Column | SIELC TechnologiesHPLC Retention of Polysorbate on Primesep D Column | SIELC Technologies
It is often required to quantitate Polysorbate (Polysorbate/Tween 20, Polysorbate/Tween 40, Polysorbate 60/Tween 60 and ... Polysorbates exist in form of oligomers. All oligomers are separated on Primesep D HPLC column. One of the oligomers can be ... Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are often used in cosmetics to ... Polysorbates are oily liquids derived from PEG-ylated sorbitan (a derivative of sorbitol) esterified with fatty acids. ...
https://sielc.com/Application-HPLC-Retention-of-Polysorbate-on-Primesep-D-Column
Plantain and Broccoli May Inhibit Crohns Relapse, Polysorbate 80 May Increase Risks | Crohns Disease ForumPlantain and Broccoli May Inhibit Crohn's Relapse, Polysorbate 80 May Increase Risks | Crohn's Disease Forum
Food emulsifiers used in the food industry, polysorbate 60, polysorbate 80. Test:. *Observation of E Coli 605 translocation ... Polysorbate-80 is a COMMON ingredient in processed foods, it is an emulsifier.. Fun fact: one of the inactive ingredients of ... polysorbate?heh, inactive in regards to what??. id like to know what ingredient in lialda is worsening and or causing joint ... Polysorbate 60/80 a subject dear to my heart as well as all food emulsifiers as well as lecithin. Peg 6/12 in toothpaste,CMC, ...
https://crohnsforum.com/threads/plantain-and-broccoli-may-inhibit-crohns-relapse-polysorbate-80-may-increase-risks.21727/
20 Polysorbate at Best Price in Mumbai - Manufacturer,Supplier,Maharashtra20 Polysorbate at Best Price in Mumbai - Manufacturer,Supplier,Maharashtra
ORCHEM PRODUCTS is emerged as a supplier,manufacturer of 20 Polysorbate from Mumbai,Maharashtra,India ... 20 Polysorbate belongs to the class of emulsifiers and is widely used in cosmetics and beauty products. It is used as a non- ... Furthermore, one can get this 20 Polysorbate from us at reasonable cost. ...
https://www.orchemproducts.in/20-polysorbate-7052670.html
Polysorbate 60 - Indeed LabsPolysorbate 60 - Indeed Labs
This ingredient is used to mix non-miscible substances (like oil and water) and to alter product thickness. It can also be used as a cleansing agent to remove excess oil and dirt from the skins surface.. ...
https://indeedlabs.com/glossary/polysorbate-60/
polysorbate 80polysorbate 80
American College of Pediatrics, antivaccine, Cervarix, Gardasil, hpv, polysorbate 80, premature ovarian failure, vaccine ... antivaccine, Byram Bridle, COVID-19, COVID-19 vaccine, female infertility, infertility, lipid nanoparticles, polysorbate 80, ... This time, its the lipid nanoparticles attacking the ovaries, echoing very old claims about polysorbate-80. Truly, everything ...
https://www.respectfulinsolence.com/tag/polysorbate-80/
Global Polysorbate Market Size - Industry Overview, 2019-2026Global Polysorbate Market Size - Industry Overview, 2019-2026
The global polysorbate market was valued at USD 995.4 million in 2018 and is projected to register a CAGR of 4.9% from 2019 to ... Polysorbate Market Analysis, By Grade (Polysorbate 20, 40, 60, 80, 81), By Product, By Administrative Route, By Usage, By ... Polysorbate 20 is expected to grow at a CAGR of 5.1% during the forecast period. The grade 20 is a nonionic surfactant that is ... The global polysorbate market was valued at USD 995.4 Million in 2018 and is projected to register a CAGR of 4.9% from 2019 to ...
https://www.reportsanddata.com/report-detail/polysorbate-market
Polysorbate 80: Why Is Polysorbate 80 In My Product? Is It Safe To Use? - The Dermatology ReviewPolysorbate 80: Why Is Polysorbate 80 In My Product? Is It Safe To Use? - The Dermatology Review
Polysorbate 80 vs Polysorbate 20 There is very little difference between polysorbate 80 and polysorbate 20. They have similar ... It makes polysorbate a slightly weaker emulsifier than polysorbate 80. This means that polysorbate 80 is better at emulsifying ... Polysorbate 80 is similar in function to polysorbate 20, and 60 which are used in skincare and cosmetic products as well. ... In polysorbate 20 it is lauric acid and in polysorbate 80 it is oleic acid. This difference has little effect on the abilities ...
https://thedermreview.com/polysorbate-80/
Tellspecopedia » Polysorbate 65Tellspecopedia » Polysorbate 65
Polysorbate 65 may aggravate propylene glycol sensitivity.. Keep in mind. The fatty acids used to synthesize polysorbates may ... Polysorbate 65 is a synthetically produced emulsifier and dispersing agent used to carry flavors and colors in foods. ... Polysorbate 65 is considered safe and has no adverse effects reported at the levels present in food. ...
http://www.tellspecopedia.com/Ingredients/polysorbate-65/
EWG rating for Block Out DST Elements Tinted Daily Use Moisturizing Lotion, SPF 30; | EWGs Guide to SunscreensEWG rating for Block Out DST Elements Tinted Daily Use Moisturizing Lotion, SPF 30; | EWG's Guide to Sunscreens
POLYSORBATE-20. Concerns: Non-reproductive organ system toxicity (low), Contamination concerns (ETHYLENE OXIDE and 1,4-DIOXANE) ... POLYSORBATE 20, VP/EICOSENE COPOLYMER, TRICETEARETH-4 PHOSPHATE, CERA ALBA, POLYACRYLAMIDE, C13-14 ISOPARAFFIN, LAURETH-7, ...
https://www.ewg.org/sunscreen/about-the-sunscreens/940354/Block_Out_DST_Elements_Tinted_Daily_Use_Moisturizing_Lotion_SPF_30/
Polysorbate 80 Archives - SkinForYouPolysorbate 80 Archives - SkinForYou
Polysorbates and Sorbitan Esters for Pharmaceutical… | BASF PharmaPolysorbates and Sorbitan Esters for Pharmaceutical… | BASF Pharma
BASF offers a broad portfolio of functional excipients including our pharmaceutical grade polysorbate and sorbitan esters. ...
https://pharma.basf.com/chemistry/polysorbates-and-sorbitan-esters
Polysorbate - 20 Manufacturer,Supplier,Exporter
Manufacturer,Supplier and Exporter of Polysorbate - 20 at most reasonable prices. Inquire us for quality Polysorbate - 20. ... This Polysorbate - 20 is offered in different packaging options to cater to the varied needs of our esteemed clients. ...
https://m.mohiniorganics.in/polysorbate-20-935902.html
Polysorbate 20 Fungal Acne - LifeStyleAboutPolysorbate 20 Fungal Acne - LifeStyleAbout
Fungal acne looks a lot like hormonal acne or bacterial acne, but the culprit isnt the same as other types of acne. Instead, it is an overgrowth of yeast that… Read more » ...
https://lifestyleabout.com/tag/polysorbate-20-fungal-acne/
Polysorbate 20 | Soap et al.Polysorbate 20 | Soap et al.
Polysorbate is approved for use in cosmetics in Europe by the EC and approved in the USA by the FDA. Use Polysorbate 20 in ... If you are looking to combine heavier oils with water then use Polysorbate 80. Both Polysorbate 20 and 80 can be used in the ... Solubiser, Polysorbate 20 is regarded as a safe chemical in skincare and is used as an emulsifier to combine oil and water. ... Polysorbate 20 is best used for light oils like fragrance or essential oils. ...
https://soapetal.com.ng/product/polysorbate-20/
Whats the Deal with Polysorbate? - Everyday EssentialsWhat's the Deal with Polysorbate? - Everyday Essentials
Ever wonder what Polysorbate is or why we include it in some of our DIY recipes? Well share everything you need to know about ... Now I understand polysorbate I will be more willing to use things with polysorbates in them after reading what kind! Thank you! ... What is Polysorbate?. In purely basic terms, Polysorbates are a class of emulsifiers used in cosmetics, food preparation, and ... The Difference Between Polysorbate 20 & 80. The number that follows the term Polysorbate relates to the type of fatty acid ...
https://blog.planttherapy.com/blog/2020/06/17/whats-the-deal-with-polysorbate/
The Streets of Polysorbate XL - Gamer WalkthroughsThe Streets of Polysorbate XL - Gamer Walkthroughs
After the cut-scene Roger finds himself half embedded in the road. Wait for the robot to walk past from right to left and use the Hand icon on it as it gets close. Roger will grab onto it and pull himself out of the hole. Look closely at the bike to the right. Grab the ID Card thats hanging from it.. There are some events that take place randomly while youre walking around the streets. As you walk around keep an eye out for the Photo Booth. When you see it use the Buckazoid from your inventory on the Photo Booth to take a picture.. Open your inventory and use the Photos on the ID Card to make your own Fake ID. While youre wandering around the streets enter the Arcade and talk to the big alien leaning on the arcade machine. Have a game with him but you cant win at the moment.. Leave the Arcade and continue wandering around until you see a man wearing a trenchcoat. Speak with him twice to find out hes an Endodroid Runner. He gives you a Datacorder so Roger can help track down his ...
https://gamerwalkthroughs.com/space-quest-6/the-streets-of-polysorbate-xl/
DailyMed - PLAQUENIL- hydroxychloroquine sulfate tabletDailyMed - PLAQUENIL- hydroxychloroquine sulfate tablet
Polysorbate 80 - BeScented Soap and Candle Making SuppliesPolysorbate 80 - BeScented Soap and Candle Making Supplies
You can see how this popup was set up in our step-by-step guide: https://wppopupmaker.com/guides/auto-opening-announcement-popups/. ...
https://bescented.com/product-category/bath-bomb-supplies/bath-bomb-supplies-polysorbate-80/?product_orderby=rating
Polysorbate 80 Supplier,Polysorbate 80 Trader in India
V. PHARMACHEM is supplier and trader of Polysorbate 80 in India.Our company providing Polysorbate 80 at market leading price. ... Polysorbate 80. Polysorbate 80 is an excellent solubilizer of essential oils, is a wetting agent, viscosity modifier, ...
http://m.vpharmachem.co.in/polysorbate-80-3677389.html
Polysorbate 80 gr.100 Difco / Becton Dickinson / BBL - Di GiovanniPolysorbate 80 gr.100 Difco / Becton Dickinson / BBL - Di Giovanni
Polysorbate 80 BP/USP/FCC , importer buy trade lead, Bangladesh, DhakaPolysorbate 80 BP/USP/FCC , importer buy trade lead, Bangladesh, Dhaka
Buy trade lead for Polysorbate 80 BP/USP/FCC posted by importers, buyers in infobanc.com b2b portal on 2014-10-21 ... Polysorbate 80 (Polyoxyethylene sorbitan monooleate) BP/USP/FCC- 1000 kg ( 5 drums), CAS : 9005-65-6. This time, quantity is ...
https://buyers.infobanc.com/trade-leads/importers/130403/polysorbate-80-bpuspfcc.htm
EmulsifierTWEENSurfactantGlobal Polysorbate MarketIngredientIngredientsCharacterization of PolysorbatesEmulsifiersSolubilizerCosmeticsGlycolSurfactantsFormulationsSorbitan estersType of fatty acidExcipientInfluenza vaccinesFatty acidsPolyethyleneEthylene oxideVaccinesHeavier oilsBath BombsSolubilizersPOLYOXYETHYLENEMoleculeSpraysProductsInfertilityAmericaESSENTIALPharmaceuticalAllergicAdverse effects
Emulsifier15
  • Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. (ncats.io)
  • Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the manufacture of the popular antiarrhythmic amiodarone. (ncats.io)
  • Translocation of E coli across M-cells is reduced by soluble plant fibres, particularly plantain and broccoli, but increased by the emulsifier Polysorbate-80. (crohnsforum.com)
  • Polysorbate-80 is a COMMON ingredient in processed foods, it is an emulsifier. (crohnsforum.com)
  • Polysorbate 80 is used as a surfactant, emulsifier, and solubilizer, helping to produce smooth, easy to apply skincare and body care products. (thedermreview.com)
  • Polysorbate 80 improves the texture of products by working as a surfactant, emulsifier and solubilizer. (thedermreview.com)
  • In cosmetics and personal care products, polysorbate 80 functions as a surfactant, emulsifier, and solubilizer. (thedermreview.com)
  • Polysorbate 80 is also an emulsifier. (thedermreview.com)
  • As an emulsifier, polysorbate 80 is often used in formulations that contain both water and oil components. (thedermreview.com)
  • To address this problem, an emulsifier like polysorbate 80 can be added to help the droplets remain dispersed and so that the product remains mixed and doesn't separate. (thedermreview.com)
  • It makes polysorbate a slightly weaker emulsifier than polysorbate 80. (thedermreview.com)
  • Polysorbate 65 is a synthetically produced emulsifier and dispersing agent used to carry flavors and colors in foods. (tellspecopedia.com)
  • Polysorbate 20 is regarded as a safe chemical in skincare and is used as an emulsifier to combine oil and water. (com.ng)
  • Polysorbate 20, unlike Polysorbate 80, is used more in cosmetic formulations rather than as an emulsifier and stabilizer in food. (planttherapy.com)
  • Polysorbate 20 serves as an emulsifier and surfactant, as well as a viscosity modifier, stabilizer, and dispersing agent. (planttherapy.com)
TWEEN2
  • It is often required to quantitate Polysorbate (Polysorbate/Tween 20, Polysorbate/Tween 40, Polysorbate 60/Tween 60 and Polysorbate 80) by HPLC in various formulations. (sielc.com)
  • Captured fleas should be placed in a 1-dram vial containing a 2% saline solution, to which one or two drops of Tween 80 (polysorbate) per liter has been added. (cdc.gov)
Surfactant4
  • Polysorbate 80 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent. (sigmaaldrich.com)
  • Non-ionic surfactant polysorbate (PS) is an excipient in formulation solutions serving as a shear protectant to stabilize biotherapeutics, prevent agitation-induced aggregation, and minimize surface adsorption. (biorxiv.org)
  • Polysorbate 80 is a surfactant. (thedermreview.com)
  • Due to its ability to work as a surfactant, polysorbate 80 is often found in many different cleansers and body washes. (thedermreview.com)
Global Polysorbate Market1
  • The global polysorbate market was valued at USD 995.4 Million in 2018 and is projected to register a CAGR of 4.9% from 2019 to reach USD 1,478.0 Million by the year 2026. (reportsanddata.com)
Ingredient5
  • Polysorbate 80 is a skincare ingredient used in cosmetics and personal care products to improve the texture of products. (thedermreview.com)
  • When talking about emulsifiers, that questionable ingredient was most likely some variant of Polysorbate. (planttherapy.com)
  • The next vastly popular vaccine ingredient to be researched and synthesized is polysorbate 80. (naturalnews.com)
  • Tell your doctor if you are allergic to docetaxel injection or drugs made with polysorbate 80, an ingredient found in some medications. (medlineplus.gov)
  • For this reason, CDC recommends that people who have had a severe or immediate reaction to the vaccine, any ingredient in the vaccine, or to polysorbate (which is closely related to PEG) not receive the mRNA vaccines. (cdc.gov)
Ingredients1
  • The ingredients of Polysorbate help dissolve other ingredients in a solution in which they will not usually dissolve. (emergenresearch.com)
Characterization of Polysorbates2
  • Trends on Analytical Characterization of Polysorbates and Their Degradation Products in Biopharmaceutical Formulations. (coriolis-pharma.com)
  • Industry Perspective on the Use and Characterization of Polysorbates for Biopharmaceutical Products Part 2: Survey Report on Control Strategy Preparing for the Future. (novartis.com)
Emulsifiers4
  • Polysorbates act as humectants, solubilizers, and emulsifiers. (oxiteno.com)
  • Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. (sielc.com)
  • 20 Polysorbate belongs to the class of emulsifiers and is widely used in cosmetics and beauty products. (orchemproducts.in)
  • In purely basic terms, Polysorbates are a class of emulsifiers used in cosmetics, food preparation, and some pharmaceuticals. (planttherapy.com)
Solubilizer1
  • Polysorbate 80 is an excellent solubilizer of essential oils, is a wetting agent, viscosity modifier, stabilizer and a dispersing and foaming agent. (vpharmachem.co.in)
Cosmetics4
  • The polysorbate 20 segment is forecasted to hold the largest market over the forecast timeframe owing to the increasing use of this type of polysorbate in the cosmetics industry. (emergenresearch.com)
  • Besides, other major factors that are anticipated to boost the polysorbate market in the Asia Pacific are the rising healthcare industry and increasing government spending in the cosmetics and healthcare industries. (emergenresearch.com)
  • In addition to its function in cosmetics, polysorbate 80 can be used to prepare a wide variety of products in the food, drug, textile, and metalworking industries. (thedermreview.com)
  • Polysorbate is approved for use in cosmetics in Europe by the EC and approved in the USA by the FDA. (com.ng)
Glycol1
Surfactants2
  • Among many other applications, polysorbates (PSs) are used as the most common surfactants in biopharmaceutical products in particular to protect proteins against interfacial stress. (coriolis-pharma.com)
  • Polysorbate (PS) 20 and 80 are the main surfactants used to stabilize biopharmaceutical products. (novartis.com)
Formulations5
  • After being cultured for indicated periods of time, Caco-2 cells were treated with individual test formulations (containing Polysorbate 80) in a final volume of 200 μL per well in 96-well plates at specified concentrations diluted with culture medium for two hours. (ncats.io)
  • One of the oligomers can be used in quantitating polysorbate in various drug and food formulations. (sielc.com)
  • When used alone, polysorbate 80 is excellent at dissolving essential oils into formulations and has good function as a thickener, stabilizer and prevents static. (thedermreview.com)
  • Making polysorbate 80 better suited as a food additive and polysorbate 20 more suitable for cosmetic formulations that utilize lighter oils. (thedermreview.com)
  • Polysorbate 80 is used in both cosmetic formulations and as an emulsifying and stabilizing additive in the food manufacturing process. (planttherapy.com)
Sorbitan esters2
  • Polysorbates are produced through the ethoxylation of sorbitan esters, which are delivered through sorbitol's reaction with various fatty acids. (oxiteno.com)
  • BASF offers a broad portfolio of functional excipients including our pharmaceutical grade polysorbate and sorbitan esters. (basf.com)
Type of fatty acid1
  • The number that follows the term Polysorbate relates to the type of fatty acid connected to the ethoxylated sorbitan part of the molecule. (planttherapy.com)
Excipient2
  • Polysorbate is an excipient used for the stabilization of aqueous preparations of parenteral drugs. (emergenresearch.com)
  • Polysorbate 80 is also used as an excipient in some European and Canadian influenza vaccines. (ncats.io)
Influenza vaccines1
  • Influenza vaccines contain 25 μg of polysorbate 80 per dose. (ncats.io)
Fatty acids3
  • Polysorbates are oily liquids derived from PEG-ylated sorbitan (a derivative of sorbitol) esterified with fatty acids. (sielc.com)
  • Polysorbates are an oily liquid which are derived from ethoxylated sorbitan esterified with fatty acids. (reportsanddata.com)
  • The fatty acids used to synthesize polysorbates may come from animal sources. (tellspecopedia.com)
Polyethylene1
  • Based on the number 20 followed by the 'polyethylene' part the total number in the molecule, polysorbate is divided into various products such as the grade 20, grade 40, grade 60, and grade 80 among others. (reportsanddata.com)
Ethylene oxide2
  • Sorbitan is reacted with 80 units of ethylene oxide, which is where the 80 in polysorbate 80 comes from. (thedermreview.com)
  • In both Polysorbate 20 and 80, the contaminants that cause concern are Ethylene Oxide and 1,4-Dioxane. (planttherapy.com)
Vaccines3
  • Besides, the growing application of polysorbate in the pharmaceutical industry to prepare several vaccines is anticipated to boost the market growth shortly. (emergenresearch.com)
  • Many vaccines contain polysorbate 80, which can cause anaphylactic shock. (naturalnews.com)
  • Polysorbate 80 is a chemical found in most flu shots and the highly controversial HPV vaccines - where "coincidentally" there is a large statistical history of teenage girls going into anaphylactic shock, losing use of their limbs, and slipping into comas. (naturalnews.com)
Heavier oils2
  • This means that polysorbate 80 is better at emulsifying heavier oils. (thedermreview.com)
  • If you are looking to combine heavier oils with water then use Polysorbate 80. (com.ng)
Bath Bombs1
  • Due to the enhanced emulsifying properties of Polysorbate 80, it is ideal in DIYs such as bath bombs. (planttherapy.com)
Solubilizers1
  • PlantaSol CCG can be used to replace, or partially replace, Polysorbate 20 and other solubilizers in essential oil or fragrance oil spray mist products. (theherbarie.com)
POLYOXYETHYLENE1
  • Polysorbate 80 (Polyoxyethylene sorbitan monooleate) BP/USP/FCC- 1000 kg ( 5 drums), CAS : 9005-65-6. (infobanc.com)
Molecule1
  • Polysorbate 80 is produced by the ethoxylation of a molecule called sorbitan. (thedermreview.com)
Sprays1
  • Use Polysorbate 20 in applications where you need water and oil to combine a prime example would be room sprays where you have oil that you want to disperse in water. (com.ng)
Products7
  • Degradation of polysorbate can lead to particle formation in drug products, which is a major quality concern and potential patient risk factor. (biorxiv.org)
  • The polysorbate market is expected to grow significantly due to the increasing demand for skincare products, makeup bases and foundations, and fragrance powders. (emergenresearch.com)
  • The syrup segment is expected to dominate the market throughout the forecast period due to the rising use of polysorbate to prepare hair growth products and the baking industry. (emergenresearch.com)
  • Polysorbate 80 is similar in function to polysorbate 20 , and 60 which are used in skincare and cosmetic products as well. (thedermreview.com)
  • The critical takeaway here is that not all Polysorbate products are created equal. (planttherapy.com)
  • The dangers and risks associated with Polysorbate aren't with the product itself, but the contamination concerns of lower quality, lower grade Polysorbate products. (planttherapy.com)
  • These contaminants can be avoided by sourcing Polysorbate from reputable suppliers that only provide the best, highest quality products available. (planttherapy.com)
Infertility1
  • Since the early 1990s, scientists have known that injecting polysorbate 80 causes infertility in mammals. (naturalnews.com)
America2
  • Due to the robust presence of various producers in countries in these regions, North America and Europe are anticipated to account for significant market growth in the polysorbate market. (emergenresearch.com)
  • In Europe and America, people eat about 100 mg of polysorbate 80 in foods per day on average. (ncats.io)
ESSENTIAL1
  • Polysorbate 20 is best used for light oils like fragrance or essential oils. (com.ng)
Pharmaceutical2
  • This substance is widely used in the food industry to emulsify salad dressings and chocolates and in the pharmaceutical sector to disperse active compounds into medicines due to the special characteristics and safety of Polysorbate-80. (emergenresearch.com)
  • Polysorbates have ample applications in the pharmaceutical and veterinary health sectors. (reportsanddata.com)
Allergic3
  • Here's why: Polysorbate 80 is a solubilizing agent able to cause severe nonimmunologic anaphylactoid reactions by suppressing your immune system while causing a severe allergic reaction - and this combination of events can kill you . (naturalnews.com)
  • What about if you, your children, your parents or grandparents are allergic to injecting aluminum and polysorbate 80 in conjunction with 20 combinations of living toxoid bacteria, whose toxicity has been "inactivated" or "suppressed" by chemical or heat treatment? (naturalnews.com)
  • Ask your doctor if you are unsure if a medication you are allergic to contains polysorbate 80. (medlineplus.gov)
Adverse effects2
  • The Joint FAO / WHO Expert Committee on Food Additives (JECFA) established in 197, based on data on the absence of adverse effects at doses up to 2500 mg / kg / day and safety factor 100, the maximum allowable daily intake of polysorbates in 25 mg / Kg. (ncats.io)
  • Polysorbate 65 is considered safe and has no adverse effects reported at the levels present in food. (tellspecopedia.com)