Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation. (1/414)
Methotrexate (MTX) is one of the most active and widely used agents for the treatment of acute lymphoblastic leukemia (ALL). To elucidate the mechanism for higher accumulation of MTX polyglutamates (MTX-PG) in hyperdiploid ALL and lower accumulation in T-lineage ALL, expression of the reduced folate carrier (RFC) was assessed by reverse transcription-polymerase chain reaction in ALL blasts isolated from newly diagnosed patients. RFC expression exhibited a 60-fold range among 29 children, with significantly higher expression in hyperdiploid B-lineage ALL (median, 11.3) compared with nonhyperdiploid ALL (median, 2.1; P <.0006), but no significant difference between nonhyperdiploid B-lineage and T-lineage ALL. Furthermore, mRNA levels of RFC (mapped by FISH to chromosome 21) were significantly related to chromosome 21 copy number (P =.0013), with the highest expression in hyperdiploid ALL blasts with 4 copies of chromosome 21. To assess the functional significance of gene copy number, MTX-PG accumulation was compared in ALL blasts isolated from 121 patients treated with either low-dose MTX (LDMTX; n = 60) or high-dose MTX (HDMTX; n = 61). After LDMTX, MTX-PG accumulation was highest in hyperdiploid B-lineage ALL with 4 copies of chromosome 21 (P =.011), but MTX-PG accumulation was not significantly related to chromosome 21 copy number after HDMTX (P =.24). These data show higher RFC expression as a mechanism for greater MTX accumulation in hyperdiploid B-lineage ALL and indicate that lineage differences in MTX-PG accumulation are not due to lower RFC expression in T-lineage ALL. (+info)Antitumor activity of poly(L-glutamic acid)-paclitaxel on syngeneic and xenografted tumors. (2/414)
Poly(L-glutamic acid)-paclitaxel (PG-TXL) is a new water-soluble paclitaxel derivative that has shown remarkable antitumor activity against both ovarian and breast tumors. The purpose of this study was to test whether the antitumor efficacy of PG-TXL depends on tumor type, as is the case for paclitaxel, and to test whether paclitaxel-resistant tumors could be responsive to PG-TXL. We evaluated the therapeutic activity of PG-TXL against four syngeneic murine tumors (MCa-4, MCa-35, HCa-1, and FSa-II) inoculated i.m. into C3Hf/Kam mice, a human SKOV3ip1 ovarian tumor injected i.p. into nude mice, and a human MDA-MB-435Lung2 breast tumor grown in the mammary fat pad of nude mice. Two paclitaxel-responsive murine tumors, MCa-4 and MCa-35, showed significant growth delay with PG-TXL given as a single i.v. injection at its maximum tolerated dose of 160 mg of equivalent paclitaxel/kg or even at a lower dose of 120 mg of equivalent paclitaxel/kg. The other two murine tumors, HCa-1 and FSa-II, did not respond particularly well to either of the two agents, although significant growth delay was observed for both tumors with PG-TXL. In mice with SKOV3ip1 tumors, the median survival times for mice treated with PG alone and PG-TXL at doses of 60 or 120 mg of equivalent paclitaxel/kg were 43, 61, and 75 days, respectively; no survival difference was found between paclitaxel-treated and Cremophor vehicle-treated mice. In mice with MDA-MB-435Lung2 tumor, PG-TXL at a dose of 120 mg of equivalent paclitaxel/kg produced regression of the tumor in 50% of the animals, and in the remaining mice, micrometastases in the lung were found only in 25% of the animals. In comparison, treatment with paclitaxel at 60 mg/kg did not result in tumor regression, and the rate of lung metastases was 42%. These results clearly demonstrate that PG-TXL has significant therapeutic activity against breast and ovarian tumors tested in this study. Future studies to elucidate the mechanism of action of PG-TXL and to assess its clinical applications are warranted. (+info)An inhibitor of exported Mycobacterium tuberculosis glutamine synthetase selectively blocks the growth of pathogenic mycobacteria in axenic culture and in human monocytes: extracellular proteins as potential novel drug targets. (3/414)
Mycobacterium tuberculosis and other pathogenic mycobacteria export abundant quantities of proteins into their extracellular milieu when growing either axenically or within phagosomes of host cells. One major extracellular protein, the enzyme glutamine synthetase, is of particular interest because of its link to pathogenicity. Pathogenic mycobacteria, but not nonpathogenic mycobacteria, export large amounts of this protein. Interestingly, export of the enzyme is associated with the presence of a poly-L-glutamate/glutamine structure in the mycobacterial cell wall. In this study, we investigated the influence of glutamine synthetase inhibitors on the growth of pathogenic and nonpathogenic mycobacteria and on the poly-L-glutamate/glutamine cell wall structure. The inhibitor L-methionine-S-sulfoximine rapidly inactivated purified M. tuberculosis glutamine synthetase, which was 100-fold more sensitive to this inhibitor than a representative mammalian glutamine synthetase. Added to cultures of pathogenic mycobacteria, L-methionine- S-sulfoximine rapidly inhibited extracellular glutamine synthetase in a concentration-dependent manner but had only a minimal effect on cellular glutamine synthetase, a finding consistent with failure of the drug to cross the mycobacterial cell wall. Remarkably, the inhibitor selectively blocked the growth of pathogenic mycobacteria, all of which release glutamine synthetase extracellularly, but had no effect on nonpathogenic mycobacteria or nonmycobacterial microorganisms, none of which release glutamine synthetase extracellularly. The inhibitor was also bacteriostatic for M. tuberculosis in human mononuclear phagocytes (THP-1 cells), the pathogen's primary host cells. Paralleling and perhaps underlying its bacteriostatic effect, the inhibitor markedly reduced the amount of poly-L-glutamate/glutamine cell wall structure in M. tuberculosis. Although it is possible that glutamine synthetase inhibitors interact with additional extracellular proteins or structures, our findings support the concept that extracellular proteins of M. tuberculosis and other pathogenic mycobacteria are worthy targets for new antibiotics. Such proteins constitute readily accessible targets of these relatively impermeable organisms, which are rapidly developing resistance to conventional antibiotics. (+info)Isolation of tubulin polyglutamylase from Crithidia; binding to microtubules and tubulin, and glutamylation of mammalian brain alpha- and beta-tubulins. (4/414)
Trypanosomatids have a striking cage-like arrangement of submembraneous microtubules. We previously showed that alpha- and beta- tubulins of these stable microtubules are extensively modified by polyglutamylation. Cytoskeletal microtubular preparations obtained by Triton extraction of Leishmania tarentolae and Crithidia fasciculata retain an enzymatic activity that incorporates radioactive glutamic acid in a Mg2+-ATP-dependent manner into alpha- and beta-tubulins. The tubulin polyglutamylase is extracted by 0.25 M salt. The Crithidia enzyme can be purified by ATP-affinity chromatography, glycerol-gradient centrifugation and ion-exchange chromatography. After extraction from the microtubular cytoskeleton the glutamylase forms a complex with alphabeta tubulin, but behaves after removal of tubulin as a globular protein with a molecular mass of 38x10(3). In highly enriched fractions a corresponding band is the major polypeptide visible in SDS-PAGE. The enzyme from Crithidia recognises mammalian brain tubulin, where it incorporates glutamic acid preferentially into the more acidic variants of both alpha- and beta-tubulins. Synthetic peptides with an oligoglutamyl side chain, corresponding to the carboxy-terminal end of brain alpha- and beta-tubulins, are accepted by the enzyme, albeit at low efficiency. The polyglutamylase elongates the side chain by up to 3 and 5 residues, respectively. Other properties of the tubulin polyglutamylase are also discussed. (+info)Nucleosome movement by CHRAC and ISWI without disruption or trans-displacement of the histone octamer. (5/414)
The chromatin accessibility complex (CHRAC) belongs to the class of nucleosome remodeling factors that increase the accessibility of nucleosomal DNA in an ATP-dependent manner. We found that CHRAC induces movements of intact histone octamers to neighboring DNA segments without facilitating their displacement to competing DNA or histone chaperones in trans. CHRAC-induced energy-dependent nucleosome sliding may, in principle, explain nucleosome remodeling, nucleosome positioning, and nucleosome spacing reactions known to be catalyzed by CHRAC. The catalytic core of CHRAC, the ATPase ISWI, also mobilized nucleosomes at the expense of energy. However, the directionality of the CHRAC- and ISWI-induced nucleosome movements differed drastically, indicating that the geometry of the native complex modulates the activity of its catalytic core. (+info)Development of a hepatocyte-specific prostaglandin E(1) polymeric prodrug and its potential for preventing carbon tetrachloride-induced fulminant hepatitis in mice. (6/414)
A polymeric prodrug of prostaglandin E(1) (PGE(1)) was synthesized using galactosylated poly(L-glutamic acid hydrazide) (Gal-HZ-PLGA) as a biodegradable and targetable carrier to hepatocytes. Poly(L-glutamic acid hydrazide) was prepared by reacting poly(gamma-benzyl-L-glutamate) with hydrazine monohydrate, followed by reaction with 2-imino-2-methoxyethyl-1-thiogalactosides to obtain Gal-HZ-PLGA after i.v. injection. (111)In-labeled galactosylated poly(L-glutamic acid hydrazide) ((111)In-Gal-HZ-PLGA) rapidly accumulated in the liver in a dose-dependent manner, whereas (111)In-poly(L-glutamic acid hydrazide) did not, indicating the involvement of a galactose-specific mechanism in the uptake of (111)In-Gal-HZ-PLGA. Fractionation of liver cells revealed that (111)In-Gal-HZ-PLGA was preferentially taken up by liver parenchymal cells. After being taken up by the liver, (111)In-Gal-HZ-PLGA was gradually degraded, and radioactive metabolites with low molecular weight were detected within 10 min after injection. Then, PGE(1) or [(3)H]PGE(1) was coupled to Gal-HZ-PLGA via a hydrazone bond under mild conditions to obtain PGE(1) conjugate. After i.v. injection, [(3)H]PGE(1) conjugate was rapidly taken up by the liver (more than 80% of the dose). After injection of the conjugate, (3)H radioactivity remained in the liver, representing about 70% of the dose, even at 24 h, whereas little radioactivity remained in the organ at 1 h after the injection of free [(3)H]PGE(1). Finally, its pharmacological activity was examined in mice with fulminant hepatitis induced by peritoneal injection of carbon tetrachloride. The i.v. injection of PGE(1) conjugate at a dose of 1 mg (0.074 mg PGE(1))/kg effectively inhibited the increase of plasma glutamic pyruvic transaminase activity, whereas twice this dose (0.15 mg/kg) of free PGE(1) had little effect. These results suggest that the PGE(1) conjugate is an excellent polymeric prodrug of PGE(1) for hepatitis therapy. (+info)Synthetic peptides identify the minimal substrate requirements of tubulin polyglutamylase in side chain elongation. (7/414)
The minimal sequence requirement of Crithidia tubulin polyglutamylase is already fulfilled by tubulin-related peptides carrying a free alpha-carboxylate on a glutamic acid residue. Since the product of each glutamylation step fulfills the substrate requirements necessary for the next cycle, very long side chains are generated with brain tubulin as a substrate. Up to 70 mol of glutamic acid was incorporated per alphabeta-heterodimer. We speculate that the strict choice of a particular glutamate residue for the formation of the isopeptide bond initiating a novel side chain is made by a tubulin monoglutamylase which requires the entire tubulin as substrate. (+info)Contribution of the cell wall component teichuronopeptide to pH homeostasis and alkaliphily in the alkaliphile Bacillus lentus C-125. (8/414)
A teichuronopeptide (TUP) is one of major structural components of the cell wall of the facultative alkaliphilic strain Bacillus lentus C-125. A mutant defective in TUP synthesis grows slowly at alkaline pH. An upper limit of pH for growth of the mutant was 10.4, while that of the parental strain C-125 was 10.8. Gene tupA, directing synthesis of TUP, was cloned from C-125 chromosomal DNA. The primary translation product of this gene is likely a cytoplasmic protein (57. 3 kDa) consisting of 489 amino acid residues. Introduction of the tupA gene into the TUP-defective mutant complemented the mutation responsible for the pleiotropic phenotypes of the mutant, leading to simultaneous disappearance of the defect in TUP synthesis, the diminished ability for cytoplasmic pH homeostasis, and the low tolerance for alkaline conditions. These results demonstrate that the acidic polymer TUP in the cell wall plays a role in pH homeostasis in this alkaliphile. (+info)Polyglutamic Acid is a polyamide formed by the linkage of multiple glutamic acid monomers, often derived from bacterial sources, and used in various applications including cosmetics and biomedical research due to its hygroscopic, viscoelastic, and film-forming properties.
Polyglutamic acid (PGA) is not a medical term per se, but it is a term used in biochemistry and cosmetics. Medically, it may be mentioned in the context of certain medical conditions or treatments. Here's a definition:
Polyglutamic acid is a polymer of glutamic acid, a type of amino acid. It is a natural substance found in various foods such as natto, a traditional Japanese fermented soybean dish. In the human body, it is produced by certain bacteria during fermentation processes.
PGA has been studied for its potential medical applications due to its unique properties, including its ability to retain moisture and form gels. It has been explored as a wound dressing material, drug delivery vehicle, and anti-aging cosmetic ingredient. However, it is not a widely used or recognized medical treatment at this time.
Polyglutamic acid
... (PGA) is a polymer of the amino acid glutamic acid (GA). Depending on where the individual monomers connect, ... Because the glutamic acid has a chiral center, both forms of PGA can be made from L-glutamic acid, D-glutamic acid, or a ... Johnson, Leah C.; Akinmola, Adekunle Titus; Scholz, Carmen (March 2022). "Poly(glutamic acid): From natto to drug delivery ... Bhattacharyya, D (April 1998). "Novel poly-glutamic acid functionalized microfiltration membranes for sorption of heavy metals ...
Discrepin
... contains 38 amino acid residues. It has a polyglutamic acid at its N-terminal region. Discrepin has the α and β folds ... The α-helix is formed from amino acid Ser11 until Arg21. The three antiparallel β-sheets are formed from amino acid Ile2 until ... The first five toxins of this subfamily are very much alike, but discrepin only shares 50% amino acid homology with other ...
Gated drug delivery systems
"Polyglutamic Acid-Gated Mesoporous Silica Nanoparticles for Enzyme-Controlled Drug Delivery". Langmuir. 32 (33): 8507-8515. doi ... One study done by the Martinez-Manez lab in Valencia, Spain aimed to generate MSNs linked to poly-l-glutamic acid (PGA) gates ... Ideas such as steroid loaded poly (lactic-co-glycolic acid), PLGA, microparticles came into existence. The next major jump came ...
Bacillus
In vivo, B. anthracis produces a polypeptide (polyglutamic acid) capsule that kills it from phagocytosis. The genera Bacillus ... The cell wall is made of teichoic and teichuronic acids. B. subtilis is the first bacterium for which the role of an actin-like ... The ability of different species to ferment in the acid, neutral, and alkaline pH ranges, combined with the presence of ... acid-soluble spore proteins from the round-spore-forming bacteria Bacillus aminovorans, Sporosarcina halophila and S. ureae". ...
SKIDA1
The poly-glutamic acid region shows more conservation, and is found abbreviated in species as distantly related from humans as ... Human SKIDA1 contains two poly-alanine regions, one poly-histidine region, and one poly-glutamic acid region. It's unknown if ... The C-termini of SKIDA1 (amino acids 844-908) and EPOP (amino acids 313-379) have 52% identity. The C-terminus of EPOP binds to ... while isoform 2 is 827 amino acids long; isoform 2 is missing amino acids 240-318 from isoform 1. Isoform 1 is predicted to ...
Polycarboxylates
Polyamino acids like polyaspartic acid and polyglutamic acid have better biodegradability but lower chelating performance than ... They are polymers of acrylic acid or copolymers of acrylic acid and maleic acid. The polymer is used as the sodium salt (see: ...
Jyoti Prakash Tamang
1. 1. Pariyar, P., Yaduvanshi, P.S., Raghu, P. and Tamang, J.P. (2022). Screening of Poly-glutamic acid (PGA)-producing ... 6. Rai, R. and Tamang, J.P. (2022). In vitro and genetic screening of probiotic properties of lactic acid bacteria isolated ... Shangpliang, H.N.K. and Tamang, J.P. (2021). Phenotypic and genotypic characterizations of lactic acid bacteria isolated from ... Pradhan, P. and Tamang, J.P. (2021). Probiotic properties of lactic acid bacteria isolated from traditionally prepared dry ...
Small-angle X-ray scattering
Leisner, Dietrich; Imae, Toyoko (2003-08-01). "Interpolyelectrolyte Complex and Coacervate Formation of Poly(glutamic acid) ...
Natrialba
The osmotic pressure and these amino acids help to control the amount of salt within the cell. For instance, N. magadii is an ... nov., a novel extremely halophilic, aerobic, non-pigmented member of the Archaea from Egypt that produces extracellular poly(glutamic ... For example, their cellular machinery is adapted to high salt concentrations by having charged amino acids on their surfaces, ... Those harsh conditions resulted in changed composition of charged amino acids in the proteins (average isoelectric point is ...
Mono-BOC-cystamine
... chelates in poly(glutamic acid) Gd-DO3A conjugates for contrast-enhanced MR imaging". Magnetic Resonance Imaging. 24 (7): 931- ...
Crenolanib
... inhibits the ability of recombinant PDGFRβ to phosphorylate a synthetic tyrosine substrate (poly-glutamic acid- ...
Owais Mohammad
Zia Q, Khan AA, Swaleha Z, Owais M. Self-assembled amphotericin B-loaded polyglutamic acid nanoparticles: preparation, ... Dinh T, Zia Q, Zubair S, Stapleton P, Singh R, Owais M, Somavarapu S. Novel biodegradable poly(gamma-glutamic acid)- ... Nanomedicine Khan AA, Jabeen M, Khan AA, Owais M. Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal ... Liposomes have been widely considered useful as drug/enzyme/nucleic acid vehicles in therapy. However, their successful ...
Coulomb explosion
... the electrostatic repulsion of dissociated carboxyl groups of polyglutamic acid) may be part of the explosive action of ...
Gamma-glutamyl hydrolase
... folic acid conjugase, poly(gamma-glutamic acid) endohydrolase, polyglutamate hydrolase, poly(glutamic acid) hydrolase II, ...
List of MeSH codes (D12.125)
1-carboxyglutamic acid MeSH D12.125.067.750.400 - glutamates MeSH D12.125.067.750.400.700 - polyglutamic acid MeSH D12.125. ... 1-carboxyglutamic acid MeSH D12.125.119.450.400 - glutamates MeSH D12.125.119.450.400.700 - polyglutamic acid MeSH D12.125. ... 2-aminoadipic acid MeSH D12.125.119.170 - aspartic acid MeSH D12.125.119.170.150 - d-aspartic acid MeSH D12.125.119.170.275 - ... aspartic acid MeSH D12.125.067.500.150 - d-aspartic acid MeSH D12.125.067.500.275 - isoaspartic acid MeSH D12.125.067.500.400 ...
Anthrax toxin
1). The lethality of the disease is caused by the bacterium's two principal virulence factors: (i) the polyglutamic acid ... The disordered loop in domain 2 also has a pattern of alternating hydrophobic and hydrophilic amino acids, which is a pattern ... Additional electrophysiological measurements of cysteine substitutions place the amino acids of this loop inside the lumen of ... one of which lies with a Greek-key histidine within a cluster of polar amino acids. This cluster (including the two histidines ...
Cell-penetrating peptide
... poly-glutamic acid) and the linker, which confer the proper distance between these two charged residues in order to maximize ... Most CPP-nucleic acid complexes that have been proposed so far are formed through covalent bonding. A range of CPP-nucleic acid ... charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or ... CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids ...
PGA
... a chemical substance that is a metabolic intermediate in both glycolysis and the Calvin cycle Polyglutamic acid, a polymer of ... the glutamic acid (one of proteinogenic amino acids) Polyglycolic acid, another name for polyglycolide Propylene glycol ... PGA Championship New Zealand PGA Championship South African PGA Championship Indonesia PGA Championship 3-Phosphoglyceric acid ...
Anthrax
... and a polyglutamic acid capsule. Nonetheless, the Vollum strain, developed but never used as a biological weapon during the ... which contains only the anthrax toxin virulence plasmid and not the polyglutamic acid capsule expressing plasmid. Strain 836, ... peracetic acid, ozone gas, hypochlorous acid, sodium persulfate, and liquid bleach products containing sodium hypochlorite. ... The lethality of the anthrax disease is due to the bacterium's two principal virulence factors: the poly-D-glutamic acid ...
Engineered CAR T cell delivery
used poly(β-amino ester) (PBAE) particles laden with polyglutamic acid (PGA), nuclear localization signals, and T-cell ... lactic acid) (PLA) nanoparticles to form the hydrogel, then mixed CAR-T cells and IL-15 into the matrix. The sustained release ... was shown to slowly but efficiently release IL-15 and CAR-T cells from a cross-linked hyaluronic acid matrix and poly(lactic-co ... such as the hyaluronic acid hydrogel system developed by Hu et al. This system, which targets melanoma through targeting the ...
Polyglutamic acid - Wikipedia
Polyglutamic acid (PGA) is a polymer of the amino acid glutamic acid (GA). Depending on where the individual monomers connect, ... Because the glutamic acid has a chiral center, both forms of PGA can be made from L-glutamic acid, D-glutamic acid, or a ... Johnson, Leah C.; Akinmola, Adekunle Titus; Scholz, Carmen (March 2022). "Poly(glutamic acid): From natto to drug delivery ... Bhattacharyya, D (April 1998). "Novel poly-glutamic acid functionalized microfiltration membranes for sorption of heavy metals ...
SciELO - Brazil - Study of fluvial water treatability using γ-polyglutamic acid based biopolymer coagulant Study of fluvial...
Gamma-polyglutamic acid (γ-PGA) is a polymeric acid that reacts with calcium and aluminum salts contained in its formulation, ... Poly (glutamic acid) - An emerging biopolymer of commercial interest. Bioresour Technol 102: 5551-5561. and Singhal 2011, Shih ... Gamma-polyglutamic acid (γ-PGA) is a water-soluble, biodegradable, biocompatible and non-toxic anionic biopolymer obtained from ... γ-polyglutamic acid; coagulant; coagulation-flocculation and sedimentation tests; urban river; São Paulo ...
Polyglutamic acid skin care can help prevent dry patches | Well+Good
A dermatologist and cosmetic chemist explain how using polyglutamic acid skin care can help hydrate the skin and prevent dry ... Much like hyaluronic acid, polyglutamic acid is also hydrating (not exfoliating, like a lactic acid). "Polyglutamic acid is ... ASDM Beverly Hills 5% Pure Polyglutamic Acid Serum, $39. This potent polyglutamic acid-filled serum delivers serious moisture ... "What makes polyglutamic acid different from hyaluronic acid is that it forms a film on the skin that stops water from ...
acid polyglutamic - kazumi.ro
what is Polyglutamic Acid - Fashion
What is Polyglutamic Acid?
- MirraSkincare
Polyglutamic acid incorporated into skincare products provides exfoliating and brightening properties. It is an incredibly ... as polyglutamic acid stops hyaluronic acid from breaking down. Of those, the two ingredients, apply polyglutamic acid second, ... Glutamic acid is an amino acid, it is created when lots of glutamic acid molecules are linked together. This acid functions ... Polyglutamic acid or really any acid sounds like something you would want to avoid putting on your skin, especially your face. ...
Polyglutamic Acid price news - ZHENYIBIO
... trade show and technical articles about Polyglutamic Acid price manufacturers and products. ... The articles shown below are all about the Polyglutamic Acid price, through these related articles, you can get relevant ... And if these Polyglutamic Acid price articles cant solve your needs, you can contact us for relevant information. ... or latest trends about the Polyglutamic Acid price. We hope these news will give you the help you need. ...
Kocostar Polyglutamic Acid Happy Mask
Polyglutamic Acid: A New Hydrating Formula
They are perfect but not as powerful as polyglutamic acid. Neeeever heard of it?! It is fine. Skin care products with this ... So, what types of cosmetic ingredients come to your mind? Hyaluronic acid? Glycerin? ... as polyglutamic acid prolongs the action of hyaluronic acid. So, right after toning your face, apply hyaluronic acid. As the ... Polyglutamic acid (PGA) is a water-soluble peptide produced by the Bacillus species. In terms of cosmetic application, it falls ...
REB TECHNOLOGY | Polyglutamic acid, Sodium (PGA Na)
It is a water-soluble homo-polyamide consisting of D-glutamic acid and L-glutamic acid monomers connected by amide linkages ... PGA Na is a natural, multi-functional and biodegradable biopolymer produced from L-glutamic acid through a fermentation process ... Reduces the tackiness of hyaluronic acid (sodium hyaluronate) in formulations. Typical Application: Lotion, facial mask, spray ...
Gamma Polyglutamic Acid - Factory, Suppliers, Manufacturers from
Gamma Polyglutamic Acid. Gamma Polyglutamic Acid - Factory, Suppliers, Manufacturers from. Our products are widely recognized ... Gamma-Polyglutamic Acid Market Size Worth US$ 840 Mn By. January 14, 2020 17:00 ET , Source: Acumen Research and Consulting ... Best Kojic Acid,Best Kojic Acid Products.Our final goal is "To try the best, To be the Best". Please feel free to contact with ... Kojic acid skin creams: Get spotless, blemish-free skin , Most Searched Products - Times of India. You must login to keep ...
The Inkey List - Polyglutamic Acid
- Docklands Pharmacy
Polyglutamic Acid can hold 4x more moisture than Hyaluronic Acid, locking in moisture and helping the skin appear instantly ... 3% Polyglutamic Acid complex is a natural high molecular weight amino acid polymer, specifically. designed to enhance skin ... A powerful hydrator for the skin's surface, Polyglutamic Acid can hold 4x more moisture than Hyaluronic Acid, locking in ... Polyglutamic Acid","public_title":null,"options":["Default Title"],"price":1320,"weight":0,"compare_at_price":1650,"inventory_ ...
The Inkey List- Polyglutamic Acid - Collon Pharmacy
3% Polyglutamic Acid complex is a natural high molecular weight amino acid polymer, specifically designed to enhance skin ... The Inkey List- Polyglutamic Acid. €13.99. LOCK IN MOISTURE FOR SMOOTH SKIN INSTANTLY. A powerful hydrator for the skins ... Polygluatmic Acid can hold 4x more moisture than Hyaluronic Acid, locking in moisture and helping the skin appear instantly ...
Polyglutamic Acid Agricultural Grade : Lubon Biology Co.,Ltd
Polyglutamic Acid Agricultural Grade is a natural occurring, multi-functional, and biodegradable biopolymer ... Product Name :Polyglutamic acid agricultural grade. Chemical Name : Poly-L-glutamic acid. CAS No : 25513-46-6. Details : ... Gamma-poly-glutamic acid (gamma-PGA) is a natural occurring, multi-functional, and biodegradable biopolymer. It is produced ... Polyglutamic acid agricultural grade CAS No: 25513-46-6 Molecular formula: (C5H9NO4)x Molecular weight: 147.129 Introduction ...
γ- Polyglutamic acid Yantai Hongyuan Bio-fertilizer Co., Ltd.
Moisturizing Face Serum with 3% Polyglutamic Acid Complex - 30ml - Laurell
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Thin Hair Styling Products | Sephora
Polyglutamic Acid Complex 3%: A naturally occuring super hydrator that enhances skin moisturization. ... Amino Acid Peptide: Helps build strong cells around the dermal papilla regenerating the follicle. Ingredient Callouts: This ... What it is: An advanced leave-in thickening mousse blended with hyaluronic acid that adds volume to all thinning hair types for ...
Chemical Peels | AHAs & BHAs | Cult Beauty
The INKEY List Polyglutamic Acid Serum 30ml CULT CONSCIOUS CULT CONSCIOUS. Love the feeling of finding out that theres more to ... The INKEY List Polyglutamic Acid Serum 30ml CULT CONSCIOUS CULT CONSCIOUS. Love the feeling of finding out that theres more to ... The Ordinary Lactic Acid 10% + HA 2% Superficial Peeling Formulation 30ml TRENDING TRENDING. Youve got a good eye - this ... Alpha-H Liquid Gold Exfoliating Treatment with Glycolic Acid 100ml TRENDING TRENDING. Youve got a good eye - this beauty find ...
The New Star Acid: Polyglutamic Acid Takes Center Stage in Skincare, From Face Mist to Sunscreen - Getsitem
Glow Recipe was one of the first beauty brands to utilize polyglutamic acid, incorporating it alongside hyaluronic acid in ... The emergence of polyglutamic acid in the beauty industry has caused confusion among consumers who have only recently become ... At present, polyglutamic acid seems to only provide hydration and doesnt offer any additional benefits like the calming and ... Its important to keep in mind that while polyglutamic acid is considered safe, it is not a naturally occurring substance in ...
Collistar | LOOKFANTASTIC UK
The Inkey List's Polyglutamic Acid Dewy Sunscreen Is What Glowy Dreams Are Made of - Review, See Photos | celebvibez
The Inkey Lists Polyglutamic Acid Dewy Sunscreen Is What Glowy Dreams Are Made of - Review, See Photos. by admin , Mar 14, ... She adds that while you might hear polyglutamic acid can hold up to 5,000 times its weight in water, this type of data is ... And, most importantly, the protection factor: Polyglutamic Acid Dewy Sunscreen is formulated to provide a broad-spectrum SPF 30 ... agrees with Doboss assessment and states that PGA can absorb four times the amount of water as hyaluronic acid and is proven ...
I Am THE Makeup Junkie: Review: The Inkey List Polyglutamic Acid #TheInkeyList #PolyglutamicAcid #Skincare #Beauty #PGA ...
The Inkey List Polyglutamic Acid, beauty, skincare, skin, glowing skin, dewy skin, peptides, hydrated skin, epidermis, serum, ... Review: The Inkey List Polyglutamic Acid #TheInkeyList #PolyglutamicAcid #Skincare #Beauty #PGA #peptides #dewyskin # ... Four times that of hyaluronic acid! Polyglutamic acid is a naturally derived ingredient that is formed by the bacterial ... The Inkey List Polyglutamic Acid retails for $14.99 and can be purchased at www.theinkeylist.com. Like The Inkey List on ...
hyaluronic acid,chondroitin sulfate,injectable hyaluronic acid gel,γ-Polyglutamic acid,OEM for cosmetic and health food-Qufu Hi...
Browsing by Author "Saperas Plana, Núria"
Antibacterial hydrogelsderived from poly(¿-glutamic acid) nanofibers. Kasbiyan, Hamidreza; Yousefzade, Omid; Simiand, Estelle ... Biocompatible hydrogels with antibacterial properties derived from ¿-polyglutamic acid (¿-PGA) were prepared from bulk and ... glutamic acid) (PGGA), a naturally occurring biopolymer made of glutamic acid units connected by ... ... A hydrogel/nanoparticle-loaded system for the controlled delivery of small hydrophobic drugs has been prepared using poly(¿-glutamic ...
What Is Hyaluronic Acid? Benefits In Beauty | Charlotte Tilbury
... which products contain hyaluronic acid, what is hyaluronic acid and how to use hyaluronic acid in makeup and skincare secrets. ... High-Performance Serum with Hyaluronic Acid & Polyglutamic Acid. Hyaluronic Acid and Polyglutamic Acid - a HYDRATION POWERHOUSE ... WHAT IS HYALURONIC ACID? BENEFITS IN BEAUTY & HOW TO USE IT. Discover the benefits of Hyaluronic Acid, the answers to all of ... What is Hyaluronic Acid?. Hyaluronic acid is a well-known, well-loved ingredient used in beauty products around the world. Its ...
Cake Maker Tightening Butt & Leg Polish
- Truly Beauty
... ingredients are designed to tone up your tush and thighs with the help of sculpting ceramides and skin-sealing polyglutamic ... Polyglutamic Acid. Able to hold up to 1,000 times its own weight in water, PGA is one of the most hydrating ingredients around ... Glycerin, Sodium Cocoyl Isethionate, Sorbitol, Propylene Glycol, Rose (Rosa Damascena) Distillate, Stearic Acid, Myristic Acid ... Polyglutamic Acid, Ceramide Np, Ceramide Ap, Ceramide Eop, Water, Fragrance, Titanium Dioxide, Mica, Iron Oxide, Manganese ...
Origins GINZING™ BRIGHTENING EYE CREAM WITH CAFFEINE AND GINSENG - Augenpflege - warm/nicht definiert - Zalando.at
Publications at this Location : USDA ARS
Phospholipids and poly(glutamic acid)/hydrolyzed gluten: interaction and kinetics (Peer Reviewed Journal) (30-Oct-08) ... Rheological Properties of Dispersions of Spherulites from Jet-Cooked High-Amylose Corn Starch and Fatty Acids (Peer Reviewed ... Thermal properties of extruded injection-molded poly (lactic acid) and milkweed composites: degradation kinetics and enthalpic ... Thermal properties of poly (lactic acid)/milkweed composites (Proceedings) (17-Aug-08) ...
1 concealer brand try-me bundle
... polyglutamic acid, hydrolyzed ginseng saponins. (+/-): Titanium Dioxide (CI 77891), iron oxides (CI 77491, CI 77492, CI 77499). ... polyglutamic acid, hydrolyzed ginseng saponins. (+/-): Titanium Dioxide (CI 77891), iron oxides (CI 77491, CI 77492, CI 77499). ... polyglutamic acid, hydrolyzed ginseng saponins. (+/-): Titanium Dioxide (CI 77891), iron oxides (CI 77491, CI 77492, CI 77499). ... polyglutamic acid, hydrolyzed ginseng saponins. (+/-): Titanium Dioxide (CI 77891), iron oxides (CI 77491, CI 77492, CI 77499). ...
Pharmacokinetics and Targeted Drug Disposition - The University of NottinghamInkey ListHyaluronic and polyglutamic acidGlycerinIngredientsSerumHydrationLacticAMINO ACIDSMoistureFine lines and wrinkles5,000 times its weightGlutamic acidCitric acidComplexBlended with hyaluronic acidSunscreenPeptideInjectableNucleicHydrogelsSuppleAntioxidantSoybeansPolylacticIngredientSkinVitaminsProductsBiodegradableNaturallySmoothHoldProductMoisturizerPowerfulPriceApply
Inkey List1
- What makes polyglutamic acid different from hyaluronic acid is that it forms a film on the skin that stops water from evaporating," says Mark Curry, cosmetic chemist and co-founder of The Inkey List . (wellandgood.com)
Hyaluronic and polyglutamic acid1
- This uber-moisturizing-serum hybrid contains hyaluronic and polyglutamic acid to deliver moisture deep into the skin, and works for even the most sensitive of skin types. (wellandgood.com)
Glycerin5
- Grab this moisturizing serum for cheap to plump your skin with a polyglutamic acid complex plus glycerin that'll make your foundation application smooth AF. (wellandgood.com)
- Furthermore, independent trials that have examined its benefits are few in number compared to those on well-established humectants like glycerin and hyaluronic acid. (getsitem.com)
- However, Inkey List's new Polyglutamic Acid Dewy Sunscreen SPF30 is an excellent product that incorporates high levels of glycerin, which offers the best of both worlds. (getsitem.com)
- Since the essence also contains well-known moisturizing agents like glycerin and hyaluronic acid, I have no intention of discontinuing use anytime soon. (getsitem.com)
- It features 8% polyglutamic acid, squalene and glycerin, which act as a clinically proven ultra-hydrating trio. (gcimagazine.com)
Ingredients6
- Dr. Shaaira Nasir, a consultant dermatologist at Homerton University Hospital explained: "These two ingredients have a synergistic effect, as polyglutamic acid stops hyaluronic acid from breaking down. (inthemirra.com)
- Of those, the two ingredients, apply polyglutamic acid second, as its gel-like consistency locks in hyaluronic acid, which has a more watery consistency. (inthemirra.com)
- The emergence of polyglutamic acid in the beauty industry has caused confusion among consumers who have only recently become familiar with hyaluronic acid, as both ingredients share the common function of hydrating the skin and enhancing its overall health. (getsitem.com)
- And, most importantly, the protection factor: Polyglutamic Acid Dewy Sunscreen is formulated to provide a broad-spectrum SPF 30 shield, thanks to common sunscreen ingredients, including avobenozone, ensulizole, octisalate, and octocrylene. (celebvibez.com)
- The award-winning Charlotte's Magic Cream has a magic formula loved by supermodels and celebrities that contains ingredients such as BioNymph Peptide, Aloe Vera, Vitamins C&E, Rosehip Oil and Hyaluronic Acid. (charlottetilbury.com)
- Cake Maker's anti-aging active ingredients are designed to tone up your tush and thighs with the help of sculpting ceramides and skin-sealing polyglutamic acid to give the skin a fresh and healthy glow. (trulybeauty.com)
Serum2
- This potent polyglutamic acid-filled serum delivers serious moisture to your skin so that it's silky-smooth and hydrated all day long, even in the driest of weather. (wellandgood.com)
- Hyaluronic Acid and Polyglutamic Acid - a HYDRATION POWERHOUSE that's over 4X more hydrating than Hyaluronic Acid - are present in the RESULTS-DRIVEN, EXPERTLY-BLENDED formula of Charlotte's Magic Serum Crystal Elixir . (charlottetilbury.com)
Hydration3
- Those who have dry skin would best have extra hydration in the form of hyaluronic acid. (myskintips.com)
- At present, polyglutamic acid seems to only provide hydration and doesn't offer any additional benefits like the calming and soothing effects of hyaluronic acid. (getsitem.com)
- A key benefit of hyaluronic acid is that it delivers hydration to your skin. (charlottetilbury.com)
Lactic5
- Much like hyaluronic acid , polyglutamic acid is also hydrating (not exfoliating, like a lactic acid). (wellandgood.com)
- Chuysinuan P, Chimnoi N, Techasakul S, Supaphol P (2009) Gallic acid-loaded electrospun poly( l -lactic acid) fiber mats and their release characteristic. (springer.com)
- A safe bio-preservative agent, lactic acid bacteria (LAB) can inhibit the growth of pathogenic bacteria and spoilage organisms. (frontiersin.org)
- This study focused on the changes in biofilm activity and related metabolic pathways of S. aureus treated with lactic acid bacteria planktonic CFS (LAB-pk-CFS) and biofilm state (LAB-bf-CFS). (frontiersin.org)
- A significant part of the breast microbiota includes lactic acid bacteria, whose cell-free supernatant (LAB-CFS) may prevent bacteria from secreting virulence factors and lessen their pathogenicity ( 12 , 13 ). (frontiersin.org)
AMINO ACIDS4
- Our blend of 16 Amino Acids, together with Horse Chestnut, Bisabolol, Pro-Vitamin B5 and MSM, soothe and nurture. (facethefuture.co.uk)
- A nutritious and nurturing moisturiser designed with OSKIA's Bio-Mimetic Nutri-Barrier Complex, a synergistic blend of amino acids, vitamins and bio-mimetic actives, to support the skin's vital barrier function, Microbiome, Natural Moisturising Factor (NMF) and Acid Mantle, encouraging skin to rest and recuperate. (facethefuture.co.uk)
- NMF is an expansive group of chemicals and substances including amino acids, lactates, sugars, salts, PCA, urea and peptides that work together to keep the skin's surface intact, supple and hydrated. (facethefuture.co.uk)
- Important metabolic pathways such amino acids and carbohydrates metabolism were among the most noticeably altered metabolic pathways. (frontiersin.org)
Moisture9
- Polyglutamic acid is similar to hyaluronic acid in that it adds moisture to your skin, and it actually improves your skin's ability to absorb moisture," says Shari Sperling, DO , a board-certified dermatologist. (wellandgood.com)
- Polyglutamic acid consists of large molecules that create a protective film on the top of the skin preventing moisture evaporation. (myskintips.com)
- Hyaluronic acid doesn't seal the moisture on the upper layer because it consists of small molecules that tend to sink deeper into the skin. (myskintips.com)
- Compared with hyaluronic acid, we found that PGA can hold more moisture and tends to stay on top of the skin (making your skin look glassy), while HA goes deeper. (myskintips.com)
- A powerful hydrator for the skin's surface, Polyglutamic Acid can hold 4x more moisture than Hyaluronic Acid, locking in moisture and helping the skin appear instantly smoother. (docklandspharmacy.ie)
- A powerful hydrator for the skin's surface, Polygluatmic Acid can hold 4x more moisture than Hyaluronic Acid, locking in moisture and helping the skin appear instantly smoother. (collonpharmacy.ie)
- However, several consumer and clinical studies have demonstrated that polyglutamic acid can retain even more moisture than hyaluronic acid, and as a result, many beauty brands are featuring this ingredient prominently in their latest products. (getsitem.com)
- Plus, moisture-binding Polyglutamic Acid helps to prevent dryness for a visibly brighter, renewed complexion. (strivectin.com)
- Polyglutamic & Hyaluronic Acids draw in moisture to keep skin hydrated and supple. (facethefuture.co.uk)
Fine lines and wrinkles1
- As hyaluronic acid helps to firm and plump the look of skin to help it look more supple, this can also lead to a reduced appearance of fine lines and wrinkles! (charlottetilbury.com)
5,000 times its weight1
- She adds that while you might hear polyglutamic acid can hold up to 5,000 times its weight in water, this type of data is generated by evaluating the ingredient by itself. (celebvibez.com)
Glutamic acid12
- Because the glutamic acid has a chiral center, both forms of PGA can be made from L-glutamic acid, D-glutamic acid, or a mixture of both. (wikipedia.org)
- Complete regression of well-established tumors using a novel water-soluble poly(L-glutamic acid)-paclitaxel conjugate" (PDF). (wikipedia.org)
- Glutamic acid is an amino acid, it is created when lots of glutamic acid molecules are linked together. (inthemirra.com)
- PGA Na is a natural, multi-functional and biodegradable biopolymer produced from L-glutamic acid through a fermentation process with a Bacillus subtilis. (hzrebtech.com)
- It is a water-soluble homo-polyamide consisting of D-glutamic acid and L-glutamic acid monomers connected by amide linkages between α-amino and γ-carboxyl groups. (hzrebtech.com)
- Gamma-poly-glutamic acid (gamma-PGA) is a natural occurring, multi-functional, and biodegradable biopolymer. (polyglutamicacid.com)
- It is produced through fermentation by Bacillus subtilis using glutamic acid. (polyglutamicacid.com)
- PGA is consists of glutamic acid monomers crosslinked between α-amino and γ-carboxyl groups, and the molecular weight of PGA is usually between 100~1000 kDa. (polyglutamicacid.com)
- Targeted PEG-poly(glutamic acid) complexes for inhalation protein delivery to the lung. (nottingham.ac.uk)
- The highest concentration of gentamicin could be loaded into films composed of polypeptide poly-glutamic acid when the pH of the loading solution was acidic. (degruyter.com)
- First, the interaction of anionic ɣ-poly-glutamic acid (PGA) and cationic ɛ-poly-L-lysine (PLL) in solution was examined so as to better understand their behavior at interfaces. (umass.edu)
- Cationic poly-L-lysine (PLL) and anionic poly-glutamic acid (PGA) were used as a pair of oppositely charged polypeptides (pH 4.0). (umass.edu)
Citric acid1
- Rheological properties of hydrogels produced by cellulose derivatives cross-linked with citric acid, succinic acid, and sebacic acid. (usda.gov)
Complex1
- 3% Polyglutamic Acid complex is a natural high molecular weight amino acid polymer, specifically designed to enhance skin moisturization. (docklandspharmacy.ie)
Blended with hyaluronic acid1
- An advanced leave-in thickening mousse blended with hyaluronic acid that adds volume to all thinning hair types for a supple finish with enhanced shine. (sephora.com)
Sunscreen2
- A simple but thorough skincare routine consists of cleansing, toning, applying antioxidant serums, applying a hyaluronic acid product, then applying polyglutamic acid to seal everything in before finishing with sunscreen. (inthemirra.com)
- Connecticut-based, board-certified dermatologist Mona Gohara , MD, agrees with Dobos's assessment and states that PGA can absorb four times the amount of water as hyaluronic acid and is proven to plump and bring radiance to the skin, which would explain the dewy finish the sunscreen leaves behind. (celebvibez.com)
Peptide1
- Polyglutamic acid (PGA) is a water-soluble peptide produced by the Bacillus species. (myskintips.com)
Injectable2
- Her studies and postdoctoral research focused on developing polylactic acid (PLA) for use as injectable hydrogels for biomedical purposes, one of which is to act as a scaffold inside an organ where tissues can regenerate. (osaka-u.ac.jp)
- She is also researching the development of amino acid-based bioplastics, such as polyglutamic acid (PGA) and its derivatives, to produce injectable hydrogels. (osaka-u.ac.jp)
Nucleic3
- We have significant collaboration between researchers involved with pharmacokinetics and drug disposition and those in nanomaterials formulation, nucleic acid therapeutics and RNA biology, allergy and infection. (nottingham.ac.uk)
- Electrodeposition of silver amalgam particles (AgAPs) on various substrates represents a prospective approach to the development of a novel detection system applicable in the study of various electrochemically active substances, including nucleic acids and proteins. (researchgate.net)
- Electrodeposition of silver amalgam particles (AgAPs) on various substrates offers perspective tool in development of novel electrochemical detection system applicable even in direct bioelectrochemistry of nucleic acids or proteins. (researchgate.net)
Hydrogels1
- Biocompatible hydrogels with antibacterial properties derived from ¿-polyglutamic acid (¿-PGA) were prepared from bulk and electrospun nanofibers. (upc.edu)
Supple1
- Polyglutamic acid leaves skin smooth, supple, and radiant. (trulybeauty.com)
Antioxidant1
- In this study, the effects of intracellular delivery of various concentrations of gallic acid (GA) as a semistable antioxidant, gallic acid-loaded mesoporous silica nanoparticles (MSNs-GA), and cellular uptake of nanoparticles into Caco-2 cells were investigated. (springer.com)
Soybeans2
- Polyglutamic acid naturally appears in fermented soybeans but it was "discovered" by accident in 1937. (inthemirra.com)
- Polyglutamic acid is synthesized by bacteria in labs and also occurs in fermented soybeans. (myskintips.com)
Polylactic1
- Biocompatible and biodegradable amphiphilic polymeric micelles (PLA-CMCS-g-OA) were prepared by surface grafting of oleic acid and polylactic acid onto carboxymethyl chitosan and were used as templates for the crystallization of camptothecin. (bvsalud.org)
Ingredient2
- Current scientific findings support the idea that polyglutamic acid is a versatile ingredient. (myskintips.com)
- Hyaluronic acid is a well-known, well-loved ingredient used in beauty products around the world. (charlottetilbury.com)
Skin7
- But dermatologists say that applying polyglutamic acid-spiked skin care can help. (wellandgood.com)
- Mix a bit of polyglutamic acid in with your makeup foundation for a super-smooth, hydrated layer that glides on the skin," he says (though it works just as well to layer under your foundation if that's your preference). (wellandgood.com)
- Polyglutamic acid or really any acid sounds like something you would want to avoid putting on your skin, especially your face. (inthemirra.com)
- Hyaluronic acid is naturally produced by the skin. (myskintips.com)
- Hyaluronic acid can be used as part of your magic skin routine to hydrate your skin! (charlottetilbury.com)
- Choose a foundation with hyaluronic acid to further hydrate your skin and help create a dewy, fresh, healthy looking finish. (charlottetilbury.com)
- Hyaluronic acid binds to 1000 times it's weight in water, but it needs a water supply to do so, so if you apply it to dry skin it will find that water elsewhere & most likely bind to water that's lower levels of your skin, bringing it to the surface level. (dslaboratories.com)
Vitamins1
- Besides, polyglutamic acid contains many vitamins and valuable enzymes. (myskintips.com)
Products3
- However, there are many acids incorporated into skincare products because of their exfoliating and brightening properties. (inthemirra.com)
- As we age, the amount of hyaluronic acid that your body naturally produces decreases, which is why it can be found in many beauty products such as moisturisers and foundations with hyaluronic acid. (charlottetilbury.com)
- Hyaluronic acid can also be found in the formulas of makeup products! (charlottetilbury.com)
Biodegradable1
- Polyglutamic acid is edible, non-toxic to humans, and biodegradable. (myskintips.com)
Naturally1
- It's important to keep in mind that while polyglutamic acid is considered safe, it is not a naturally occurring substance in the body like hyaluronic acid. (getsitem.com)
Smooth1
- Another brand that has successfully incorporated polyglutamic acid is REN, with its remarkable Perfect Canvas Smooth, Prep & Plump Essence (priced at £43). (getsitem.com)
Hold2
- Polyglutamic acid or PGA can hold 4000 times its weight in water, this is quadruple the efficacy of water retention compared to hyaluronic acid or HA. (inthemirra.com)
- Hyaluronic acid can only hold 1000x its weight in water. (myskintips.com)
Product1
- After that, apply a product with polyglutamic acid. (myskintips.com)
Moisturizer1
- After its properties were analyzed, it was discovered that polyglutamic acid was an incredibly powerful humectant moisturizer. (inthemirra.com)
Powerful1
- They are perfect but not as powerful as polyglutamic acid. (myskintips.com)
Price2
- The articles shown below are all about the Polyglutamic Acid price , through these related articles, you can get relevant information, notes in use, or latest trends about the Polyglutamic Acid price . (zhenyibio.com)
- And if these Polyglutamic Acid price articles can't solve your needs, you can contact us for relevant information. (zhenyibio.com)
Apply1
- So, right after toning your face, apply hyaluronic acid. (myskintips.com)
