Poisons
Poisoning
Topoisomerase II Inhibitors
Dermatitis, Toxicodendron
Amphibian Venoms
Venoms produced by frogs, toads, salamanders, etc. The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. The venoms have been used as arrow poisons and include bufogenin, bufotoxin, bufagin, bufotalin, histrionicotoxins, and pumiliotoxin.
DNA Topoisomerases, Type II
Rodent Control
Toxicodendron
A genus (formerly part of Rhus genus) of shrubs, vines, or trees that yields a highly allergenic oleoresin which causes a severe contact dermatitis (DERMATITIS, TOXICODENDRON). The most toxic species are Toxicodendron vernix (poison sumac), T. diversilobum (poison oak), and T. radicans (poison ivy). T. vernicifera yields a useful varnish from which certain enzymes (laccases) are obtained.
Gastric Lavage
DNA Topoisomerases, Type I
DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.
Drug Overdose
4-Hydroxycoumarins
Anura
Anacardiaceae
DNA Cleavage
A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone of DNA. It is catalyzed enzymatically, chemically or by radiation. Cleavage may be exonucleolytic - removing the end nucleotide, or endonucleolytic - splitting the strand in two.
Amsacrine
Camptothecin
Ipecac
A syrup made from the dried rhizomes of two different species, CEPHAELIS ipecacuanha and C. acuminata. They contain EMETINE, cephaeline, psychotrine and other ISOQUINOLINES. Ipecac syrup is used widely as an emetic acting both locally on the gastric mucosa and centrally on the chemoreceptor trigger zone.
Etoposide
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
Emetics
omega-Chloroacetophenone
Plant Poisoning
Intercalating Agents
Phosgene
Toxicology
Designer Drugs
Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
Phosphines
DNA Damage
Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.
Regional Medical Programs
Drug Packaging
Containers, packaging, and packaging materials for drugs and BIOLOGICAL PRODUCTS. These include those in ampule, capsule, tablet, solution or other forms. Packaging includes immediate-containers, secondary-containers, and cartons. In the United States, such packaging is controlled under the Federal Food, Drug, and Cosmetic Act which also stipulates requirements for tamper-resistance and child-resistance. Similar laws govern use elsewhere. (From Code of Federal Regulations, 21 CFR 1 Section 210, 1993) DRUG LABELING is also available.
Organophosphate Poisoning
Alkaloids
Saxitoxin
A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.
Antineoplastic Agents, Phytogenic
Mushroom Poisoning
Carbon Monoxide Poisoning
Health Educators
Aneugens
Riot Control Agents, Chemical
Judaism
Enzyme Inhibitors
Charcoal
Coroners and Medical Examiners
Topotecan
Teniposide
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle.
Nocodazole
Ranidae
Madagascar
One of the Indian Ocean Islands off the southeast coast of Africa. Its capital is Antananarivo. It was formerly called the Malagasy Republic. Discovered by the Portuguese in 1500, its history has been tied predominantly to the French, becoming a French protectorate in 1882, a French colony in 1896, and a territory within the French union in 1946. The Malagasy Republic was established in the French Community in 1958 but it achieved independence in 1960. Its name was changed to Madagascar in 1975. (From Webster's New Geographical Dictionary, 1988, p714)
Pesticides
Cell Wall Skeleton
Environmental Illness
A polysymptomatic condition believed by clinical ecologists to result from immune dysregulation induced by common foods, allergens, and chemicals, resulting in various physical and mental disorders. The medical community has remained largely skeptical of the existence of this "disease", given the plethora of symptoms attributed to environmental illness, the lack of reproducible laboratory abnormalities, and the use of unproven therapies to treat the condition. (From Segen, Dictionary of Modern Medicine, 1992)
Benzodioxoles
Accident Prevention
Arthropod Venoms
Indenes
Shellfish Poisoning
Methylphenazonium Methosulfate
Cyanides
Fluoroacetates
Derivatives of acetic acid with one or more fluorines attached. They are almost odorless, difficult to detect chemically, and very stable. The acid itself, as well as the derivatives that are broken down in the body to the acid, are highly toxic substances, behaving as convulsant poisons with a delayed action. (From Miall's Dictionary of Chemistry, 5th ed)
Hotlines
DNA
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Shellfish
Methyl n-Butyl Ketone
Marine Toxins
Bufonidae
Prescription Drug Misuse
Mitosis
Electric Power Supplies
Molecular Structure
Spindle Apparatus
Hydrogen Cyanide
Antigens, Neoplasm
Heterocyclic Compounds, Bridged-Ring
Street Drugs
Carbonyl Cyanide m-Chlorophenyl Hydrazone
Thioridazine
2,4-Dinitrophenol
Electromagnetic Radiation
Azulenes
DNA-Binding Proteins
Dinoflagellida
Flagellate EUKARYOTES, found mainly in the oceans. They are characterized by the presence of transverse and longitudinal flagella which propel the organisms in a rotating manner through the water. Dinoflagellida were formerly members of the class Phytomastigophorea under the old five kingdom paradigm.
Sodium Oxybate
Toxins, Biological
Databases, Factual
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
Tubulin Modulators
Mutagens
Micronuclei, Chromosome-Defective
Dichlororibofuranosylbenzimidazole
DNA Breaks, Double-Stranded
Herbicides
Hazardous Substances
Podophyllotoxin
A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
Physicians' Offices
Sodium Azide
Colchicine
Color
G2 Phase
Drug Resistance, Neoplasm
Dose-Response Relationship, Drug
Bivalvia
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Microtubules
Dermoscopy
Uncoupling Agents
Emergency Service, Hospital
Cell Cycle
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Antibiotics, Antineoplastic
DNA Repair
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
Polyploidy
Paclitaxel
Drug Screening Assays, Antitumor
Dermatitis, Contact
Drug Resistance
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Catalysis
Antimetabolites
Drug-Related Side Effects and Adverse Reactions
Mites
Any arthropod of the subclass ACARI except the TICKS. They are minute animals related to the spiders, usually having transparent or semitransparent bodies. They may be parasitic on humans and domestic animals, producing various irritations of the skin (MITE INFESTATIONS). Many mite species are important to human and veterinary medicine as both parasite and vector. Mites also infest plants.
Doxorubicin
Nova Scotia
A province of eastern Canada, one of the Maritime Provinces with NEW BRUNSWICK; PRINCE EDWARD ISLAND; and sometimes NEWFOUNDLAND AND LABRADOR. Its capital is Halifax. The territory was granted in 1621 by James I to the Scotsman Sir William Alexander and was called Nova Scotia, the Latin for New Scotland. The territory had earlier belonged to the French, under the name of Acadia. (From Webster's New Geographical Dictionary, 1988, p871 & Room, Brewer's Dictionary of Names, 1992, p384)
Cell Survival
Isoquinolines
K562 Cells
Telephone
Insecticides
HeLa Cells
Tumor Cells, Cultured
Adverse Drug Reaction Reporting Systems
Naphthoquinones
Population Surveillance
Environmental Exposure
Stereoisomerism
Arthropods
Ants
Insects of the family Formicidae, very common and widespread, probably the most successful of all the insect groups. All ants are social insects, and most colonies contain three castes, queens, males, and workers. Their habits are often very elaborate and a great many studies have been made of ant behavior. Ants produce a number of secretions that function in offense, defense, and communication. (From Borror, et al., An Introduction to the Study of Insects, 4th ed, p676)
Aphidicolin
An antiviral antibiotic produced by Cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells.
Oligomycins
A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
Cell Cycle Proteins
Proteins that control the CELL DIVISION CYCLE. This family of proteins includes a wide variety of classes, including CYCLIN-DEPENDENT KINASES, mitogen-activated kinases, CYCLINS, and PHOSPHOPROTEIN PHOSPHATASES as well as their putative substrates such as chromatin-associated proteins, CYTOSKELETAL PROTEINS, and TRANSCRIPTION FACTORS.
DNA, Superhelical
Information Services
Referral and Consultation
Biological Transport, Active
Gas Chromatography-Mass Spectrometry
Adenosine Triphosphate
Mutation
Cricetinae
Predatory Behavior
Triage
Substance Abuse Detection
Protein-Serine-Threonine Kinases
Calcium antagonists ameliorate ischemia-induced endothelial cell permeability by inhibiting protein kinase C. (1/123)
BACKGROUND: Dihydropyridines block calcium channels; however, they also influence endothelial cells, which do not express calcium channels. We tested the hypothesis that nifedipine can prevent ischemia-induced endothelial permeability increases by inhibiting protein kinase C (PKC) in cultured porcine endothelial cells. METHODS AND RESULTS: Ischemia was induced by potassium cyanide/deoxyglucose, and permeability was measured by albumin flux. Ion channels were characterized by patch clamp. [Ca2+]i was measured by fura 2. PKC activity was measured by substrate phosphorylation after cell fractionation. PKC isoforms were assessed by Western blot and confocal microscopy. Nifedipine prevented the ischemia-induced increase in permeability in a dose-dependent manner. Ischemia increased [Ca2+]i, which was not affected by nifedipine. Instead, ischemia-induced PKC translocation was prevented by nifedipine. Phorbol ester also increased endothelial cell permeability, which was dose dependently inhibited by nifedipine. The effects of non-calcium-channel-binding dihydropyridine derivatives were similar. Analysis of the PKC isoforms showed that nifedipine prevented ischemia-induced translocation of PKC-alpha and PKC-zeta. Specific inhibition of PKC isoforms with antisense oligodeoxynucleotides demonstrated a major role for PKC-alpha. CONCLUSIONS: Nifedipine exerts a direct effect on endothelial cell permeability that is independent of calcium channels. The inhibition of ischemia-induced permeability by nifedipine seems to be mediated primarily by PKC-alpha inhibition. Anti-ischemic effects of dihydropyridine calcium antagonists could be due in part to their effects on endothelial cell permeability. (+info)The role of oxidative DNA damage in human arsenic carcinogenesis: detection of 8-hydroxy-2'-deoxyguanosine in arsenic-related Bowen's disease. (2/123)
Arsenic is widely distributed in nature in the form of either metalloids or chemical compounds, which cause a variety of pathologic conditions including cutaneous and visceral malignancies. Recently, reactive oxygen species have been hypothesized to be one of the causes of arsenic-induced carcinogenesis. 8-Hydroxy-2'-deoxyguanosine is one of the major reactive oxygen species-induced DNA base-modified products that is widely accepted as a sensitive marker of oxidative DNA damage. We studied the presence of 8-hydroxy-2'-deoxyguanosine by immunohistochemistry using N45.1 monoclonal antibody in 28 cases of arsenic-related skin neoplasms and arsenic keratosis as well as in 11 cases of arsenic-unrelated Bowen's diseases. The frequency of 8-hydroxy-2'-deoxyguanosine positive cases was significantly higher in arsenic-related skin neoplasms (22 of 28; 78%) than in arsenic-unrelated Bowen's disease (one of 11; 9%) (p < 0.001 by chi2 test). 8-Hydroxy-2'-deoxyguanosine was also detected in normal tissue adjacent to the arsenic-related Bowen's disease lesions. Furthermore, arsenic was detected by neutron activation analysis in the deparaffined skin tumor samples of arsenic-related disease (four of five; 80%), whereas arsenic was not detected in control samples. Our results strongly suggest the involvement of reactive oxygen species in arsenic-induced human skin cancer. Key word: neutron activation analysis. (+info)Efficient cleavage of conjugates of drugs or poisons by immobilized beta-glucuronidase and arylsulfatase in columns. (3/123)
BACKGROUND: Cleavage of conjugates is an important step in toxicological analysis, especially of urine samples. The aim of this study was to combine the advantages and to reduce the disadvantages of acid hydrolysis and conventional enzymatic hydrolysis procedures. METHODS: beta-Glucuronidase (GRD; EC 3.2.1.31) and arylsulfatase (ARS; EC 3.1.6.1) were purified and coimmobilized on an agarose gel matrix and packed into columns. RESULTS: In columns packed with GRD and ARS, the test conjugates 4-nitrophenyl glucuronide and 4-nitrophenyl sulfate added into urine could be completely cleaved within 25 min. Even the relatively stable morphine conjugates could be completely hydrolyzed within 60 min in authentic urine samples. Therefore, an incubation time of 1 h is recommended. Enzyme inhibition by matrix or by rather high concentrations of acetaminophen conjugates was tested and found to be up to 50%. However, a large excess of GRD and ARS was used. The immobilizate columns could be reused for at least 70 incubations and had a storage stability of at least 12 weeks. Carryover of analytes in reused columns could be avoided by rinsing with 200 mL/L methanol in acetate buffer. Thus, five drugs known to be contaminants added in very high concentrations into urine could be completely removed from the columns. A study on the applicability in systematic toxicological analysis showed that 120 different drugs and/or their metabolites could be detected in 35 different authentic urine samples. CONCLUSIONS: Use of immobilized and column-packed GRD and ARS is an efficient alternative for the cleavage of urinary conjugates in clinical toxicology. (+info)(+)-[3H]isradipine and [3H]glyburide bindings to heart and lung membranes from rats with monocrotaline-induced pulmonary hypertension. (4/123)
We examined the binding of a 1,4-dihydropyridine-sensitive Ca2+ channel ligand, (+)-[3H]isradipine (PN200-110), and that of an ATP-sensitive K+ (K(ATP)) channel ligand, [3H]glyburide, to heart, lung and brain membranes isolated from Sprague-Dawley rats made pulmonary hypertensive by monocrotaline, a pyrrolizidine alkaloid. A single subcutaneous injection of monocrotaline increased right ventricular systolic pressure, a measure of pulmonary arterial pressure, and the thickness of the right ventricular free wall in 3 to 4 weeks. The (+)-[3H]PN200-110 and [3H]glyburide binding site densities (Bmax) were reduced in hypertrophied right ventricles when normalized per unit protein in comparison with those of age-matched control (sham) rats, whereas the values of the dissociation constant (Kd) of both ligands bound to the hypertrophied right ventricle were not significantly changed. The [3H]PN200-110 binding to the lung membranes of the monocrotaline-induced pulmonary hypertensive rats was increased. The results indicate that the change in the binding of 1,4-dihydropyridine Ca2+ and K(ATP) channel ligands to heart membranes may contribute to the pathological alteration of cardiopulmonary structure and functions in rats with pulmonary hypertension induced by monocrotaline. (+info)Cardiac endothelin and big endothelin in right-heart hypertrophy due to monocrotaline-induced pulmonary hypertension in rat. (5/123)
OBJECTIVE: Recent observations suggest the existence of a myocardial endothelin (ET) system and its possible involvement in left-ventricular myocardial hypertrophy and failure. However, nothing is known about the role of myocardial ET in right-ventricular hypertrophy. METHODS: Rats (80-100 g) were given an intraperitoneal injection of saline (controls) or monocrotaline (50 mg/kg) resulting in pulmonary hypertension-induced myocardial hypertrophy (n = 11 in both groups). After 10 weeks, the animals were sacrificed and hearts perfused in vitro to determine levels of big ET-1 and ET-1 in coronary effluent, interstitial fluid and ventricular tissue homogenates; plasma levels were also determined. RESULTS: In monocrotaline-treated animals, weights of right ventricles were 1.5 and of right atria 1.8-fold higher than in controls (p < 0.05), indicating substantial right-ventricular hypertrophy as also evident from greatly increased myocardial production of atrial natriuretic peptide. Left-ventricular weights were not different. Release of big ET-1 in coronary effluent, and of ET-1 in coronary effluent and interstitial transudate were similar in control and hypertrophic hearts (p > 0.05). Disruption of endothelium with collagenase reduced release of both peptides close to zero, indicating endothelial (not myocardial) origin of the peptides. Levels of big ET-1 and ET-1 were similar in left ventricles of both experimental groups, but lower in right ventricles of hypertrophic than control hearts (p < 0.05), reflecting increased tissue mass rather than reduced peptide production. On the other hand, plasma levels of both peptides and of ANP were twofold and levels of angiotensin II 1.3-fold higher in rats with right-heart hypertrophy than in controls (p < 0.05 in each case). CONCLUSION: These data do not support a role for local cardiac ET-1 and/or big ET-1 in right-ventricular hypertrophy, but point to blood-borne endothelins as possible mediators. (+info)Identification of the general unknown. Application of mass selective detectors in forensic toxicology. (6/123)
One of the basic aims of forensic toxicology is the identification of previously unknown drugs and poisons. This is frequently achieved using the combination of gas chromatography and benchtop quadrupole or ion trap mass spectrometers. The influence of matrix loading on the mass spectral quality was tested, and it was found that a realistic amount of matrix changed the pattern of the spectra obtained by the ion trap mass spectrometer. Disturbed mass spectra led to unsuitable suggestions from the library search and thus rendered the identification of the "general unknown" more difficult. On the other hand, higher selectivity and lower detection limits favored the ion trap technology for target analysis because of the capability of MS-MS. (+info)Toward antibody-catalyzed hydrolysis of organophosphorus poisons. (7/123)
We report here our preliminary results on the use of catalytic antibodies as an approach to neutralizing organophosphorus chemical weapons. A first-generation hapten, methyl-alpha-hydroxyphosphinate Ha, was designed to mimic the approach of an incoming water molecule for the hydrolysis of exceedingly toxic methylphosphonothioate VX (1a). A moderate protective activity was first observed on polyclonal antibodies raised against Ha. The results were further confirmed by using a mAb PAR 15 raised against phenyl-alpha-hydroxyphosphinate Hb, which catalyzes the hydrolysis of PhX (1b), a less toxic phenylphosphonothioate analog of VX with a rate constant of 0.36 M(-1) x min(-1) at pH 7.4 and 25 degrees C, which corresponds to a catalytic proficiency of 14,400 M(-1) toward the rate constant for the uncatalyzed hydrolysis of 1b. This is a demonstration on the organophosphorus poisons themselves that mAbs can catalytically hydrolyze nerve agents, and a significant step toward the production of therapeutically active abzymes to treat poisoning by warfare agents. (+info)Fatal strychnine poisoning: application of gas chromatography and tandem mass spectrometry. (8/123)
The history and toxicological findings in a case of suicidal fatal strychnine poisoning are presented along with a description of the analytical methods. Detection and quantitation of strychnine in body fluids and tissues was performed by gas chromatography (GC) with nitrogen-phosphorus detection, using organic extraction and calibration by a standard addition method. Strychnine concentrations in subclavian blood (1.82 mg/mL), inferior vena cava blood (3.32 mg/mL), urine (3.35 mg/mL), bile (11.4 mg/mL), liver (98.6 mg/kg), lung (12.3 mg/kg), spleen (11.8 mg/kg), brain (2.42 mg/kg), and skeletal muscle (2.32 mg/kg) were determined. Confirmation of strychnine in blood and tissue was performed by GC with detection by tandem ion-trap mass spectrometry (MS). GC-MS-MS analysis, employing electron ionization followed by unit mass resolution and collision-induced dissociation of strychnine, resulted in confirmatory ions with mass-to-charge ratios of 334 (parent ion), 319, 306, 277, 261, 246, 233, and 220. Additional confirmation was provided by GC-MS-MS-MS analysis of each confirmatory ion, revealing an ion fragmentation pathway consistent with the molecular structure of strychnine. The case demonstrates body tissue and fluid distribution of strychnine in a fatal poisoning and the application of tandem MS in medical examiner casework. (+info)
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মেয়ের সঙ্গে সম্পর্কে আপত্তি, যুবককে বিষ খাওয়ালেন প্রেমিকার মা - Youth forced to take poison by lovers family in east midnapur...
Regret is poison.
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451 Skorupi / #452 Drapion
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Poisons
Carbon MonoxideToxinsCentersNauseaToxicComaAcuteAccidentalSevereSuspectExposureUnintentionalRodentArsenicMain contentSignsPoisonousOccurs when a personSeizuresDeadly poisonsContentHumansDeathsGermsALCOHOL POISONINGChronicHttpsMildExposuresFoodVictimChildhood leadRadioactiveIllnessSalmonellaToxinCyanideColorlessCommonSubstancesDosesVomitingDependsPower of poisonToxicityRisk Factors2020MercuryLocal poisonStrychnineLead to learning di
Carbon Monoxide10
- Every year there are around 60 deaths from accidental carbon monoxide poisoning in England and Wales. (www.nhs.uk)
- The symptoms of carbon monoxide poisoning are not always obvious, particularly during low-level exposure. (www.nhs.uk)
- A tension-type headache is the most common symptom of mild carbon monoxide poisoning. (www.nhs.uk)
- But unlike flu, carbon monoxide poisoning does not cause a high temperature. (www.nhs.uk)
- Your symptoms will often indicate whether you have carbon monoxide poisoning, but a blood test will confirm the amount of carboxyhaemoglobin in your blood. (www.nhs.uk)
- Mild carbon monoxide poisoning does not usually need hospital treatment, but it's still important that you seek medical advice. (www.nhs.uk)
- Symptoms for carbon monoxide poisoning often are the same as for the cold or flu. (ct.gov)
- If you and your family members are experiencing cold or flu symptoms when you are at home, but the symptoms go away when you leave, this may be a sign of carbon monoxide poisoning. (ct.gov)
- If you suspect carbon monoxide poisoning, leave your home IMMEDIATELY. (ct.gov)
- A person with signs or symptoms consistent with a diagnosis of carbon monoxide poisoning. (cdc.gov)
Toxins6
- Here are some of the "hidden toxins" or unexpected poison concern for our pets. (petpoisonhelpline.com)
- Explore the biodiversity of marine life and toxins while designing your own poison warning pattern-zig-zags, polka dots. (amnh.org)
- When germs that cause food poisoning get into our systems, they can release toxins. (kidshealth.org)
- These toxins are poisons (the reason for the name "food poisoning"), and can cause diarrhea and vomiting . (kidshealth.org)
- An Eco-terrorist and a master of toxins, Poison Ivy is a rebel with a cause, which is a relative rarity in the unhinged world of Batman foes. (chicagotribune.com)
- Poison ivy should never be burned because the smoke would contain toxins that, when inhaled, would cause what would amount to a poison ivy rash in your lungs. (newsday.com)
Centers14
- Local Poison Control Centers should be contacted immediately if a child consumes something poisonous. (medlineplus.gov)
- The packets are advertised as no more mess, spills or heavy jugs of detergent, but the American Association of Poison Control Centers is reporting a recent surge in calls about the packets making children violently ill. (yahoo.com)
- Texas poison control centers report receiving 57 of those emergency calls. (yahoo.com)
- The Centers for Disease Control and Prevention (CDC) defines childhood lead poisoning as a whole-blood lead concentration equal to or greater than 10 micrograms/dL. (encyclopedia.com)
- Listen to a first-hand account of one mom's experience with her local poison center and learn more about what poison centers do to support callers during a poison emergency. (ohsu.edu)
- Read the joint statement by the American Academy of Clinical Toxicology, American College of Medical Toxicology and the American Association of Poison Control Centers c aution about the proposed use of oleandrin for treatment of COVID-19. (ohsu.edu)
- Read the joint statement by the American Academy of Clinical Toxicology, American College of Medical Toxicology and the American Association of Poison Control Centers c aution about use of cleaning products and disinfectants. (ohsu.edu)
- Read the joint statement by the American Academy of Clinical Toxicology, American College of Medical Toxicology and the American Association of Poison Control Centers caution about toxicity from hydroxychloroquine and chloroquine. (ohsu.edu)
- It has been estimated by the Centers for Disease Control and Prevention that the economic cost of Salmonella food poisoning in the U.S. alone is between five and 17 billion dollars annually. (faqs.org)
- Pregnant women and debilitated people are susceptible to a potentially fatal form of food poisoning , according to the U.S. Centers for Disease Control. (healthcentral.com)
- The daily number of calls to poison centers "increased sharply" at the beginning of March, around the same time the virus started spreading in the U.S. The CDC has encouraged people to properly clean and disinfect high-touch surfaces - such as doorknobs, faucets and kitchen counters - to help mitigate the transmission of the novel coronavirus. (aarp.org)
- Inhaling fumes accounts for the largest percentage of the increase in calls to poison centers. (aarp.org)
- 1,319,044 calls were made to poison control centers in 2015 after a child got into a potential poison, that's over 3,600 calls a day, 150 every hour. (safekids.org)
- Specialists at poison control centers provide free, confidential, expert medical advice 24 hours a day. (safekids.org)
Nausea1
- Symptoms of acute poisoning from swallowing arsenic include nausea, vomiting , burning of the mouth and throat, and severe abdominal pains. (britannica.com)
Toxic17
- Other forms of alcohol - including isopropyl alcohol (found in rubbing alcohol, lotions and some cleaning products) and methanol or ethylene glycol (a common ingredient in antifreeze, paints and solvents) - can cause other types of toxic poisoning that require emergency treatment. (mayoclinic.org)
- Poisoning is a condition or a process in which an organism becomes chemically harmed severely ( poisoned ) by a toxic substance or venom of an animal . (wikipedia.org)
- Many substances regarded as poisons are toxic only indirectly, by toxication . (wikipedia.org)
- Samaritan Regional Poison Control Center, 602-253-3334, (if it is serious, call 9-1-1) provides around-the-clock advice and assistance with specially-trained registered nurses for patients experiencing serious toxic problems. (phoenix.gov)
- Alcohol poisoning occurs when a person drinks a toxic amount of alcohol, usually over a short period of time (binge drinking) . (www.nhs.uk)
- Abrin is highly toxic, with an estimated human fatal dose of 0.1-1 µg/kg, and has caused death after accidental and intentional poisoning. (springer.com)
- Meg Neal, Popular Mechanics , "Nature's Toxic Gifts: The Deadly Story of Poison," 4 Oct. 2020 However, resentment is like drinking poison and waiting for the other person to die. (merriam-webster.com)
- Nevertheless, here is a representative selection, in ascending order, of five truly deadly poisons, all at least a hundred times more toxic than cyanide, arsenic or strychnine. (businessinsider.com)
- This extremely toxic plant poison was famously used to kill the Bulgarian dissident Georgi Markov , exiled in London. (businessinsider.com)
- Poisoning can occur all year round and even dried material can be toxic. (rspca.org.uk)
- All parts of the plant are toxic and even a small amount could result in life-threatening poisoning. (rspca.org.uk)
- Mercury poisoning occurs when a person has ingested, inhaled, or had skin or eye contact with the toxic (poisonous) heavy metal mercury and suffers damage to his/her nervous system and other systems of the body. (encyclopedia.com)
- Also, bacteria can change mercury-two into one of mercury's most toxic organic compounds, methyl mercury, which is easily soluble (capable of being dissolved) in water and thus finds its way into the food chain , where it poisons fish and other animals. (encyclopedia.com)
- Pandora's Poison presents a solution to one of the most insidious environmental problems of our time: the global build-up of toxic chemicals. (mit.edu)
- Poisoning can occur when someone swallows something toxic, spills or splashes a dangerous substance on their skin or eyes, or inhales poisonous fumes. (wikihow.com)
- A person has alcohol poisoning if they have consumed a toxic amount of alcohol, usually over a short period. (medicalnewstoday.com)
- Moscow (AFP) - Russian opposition leader Alexei Navalny was "poisoned" by an unidentified toxic substance and doctors have sent him back to jail despite his condition, his lawyer and personal physician said Monday. (yahoo.com)
Coma4
- In the most severe cases, alcohol poisoning can lead to coma , brain damage and death. (www.nhs.uk)
- Russian opposition leader Alexei Navalny, who fell into a coma after a suspected poisoning, landed in Germany for treatment Saturday following a day-long standoff over whether he would be allowed to leave a Russian hospital. (freerepublic.com)
- In instances of serious poisoning, convulsions and coma may culminate in death. (britannica.com)
- If the alcohol poisoning is extreme, the patient can go into a coma and potentially die. (medicalnewstoday.com)
Acute10
- Acute poisoning is exposure to a poison on one occasion or during a short period of time. (wikipedia.org)
- Most biocides, including pesticides , are created to act as poisons to target organisms, although acute or less observable chronic poisoning can also occur in non-target organisms ( secondary poisoning ), including the humans who apply the biocides and other beneficial organisms . (wikipedia.org)
- Acute iron poisoning mainly involves children under age 6 who swallow pediatric or adult vitamins containing iron. (webmd.com)
- however, renal effects (membranous nephropathy, proliferative glomerulonephritis, and arteritis) have been reported with poison oak dermatitis, [ 10 ] as well as at least one case of respiratory symptoms (acute respiratory distress syndrome resulting in death) after exposure to smoke from burning poison ivy. (medscape.com)
- Poisoning may result from a single large dose ( acute poisoning) or from repeated small doses (chronic poisoning). (britannica.com)
- The treatment of acute arsenic poisoning involves washing out the stomach and the prompt administration of dimercaprol (BAL). (britannica.com)
- Acute lead poisoning , which is somewhat rare, occurs when a relatively large amount of lead is taken into the body over a short period of time. (encyclopedia.com)
- CO poisoning can be reversed if caught in time, but acute poisoning could result in permanent heart and brain damage. (shrm.org)
- There are steps that you can take if you encounter someone who could be suffering from acute alcohol poisoning. (csbsju.edu)
- These are just some of the potential signs of acute alcohol poisoning. (csbsju.edu)
Accidental4
- More than 150 people in the Unites States die every year from accidental non-fire related CO poisoning associated with consumer products. (cpsc.gov)
- Among industrial workers, arsine may be a source of accidental poisoning. (britannica.com)
- It has been theorized that the fluoride in dental products may cause accidental poisoning, if ingested in large quantities. (ehow.com)
- Deliberate or accidental poisoning with large doses of medication or drugs is often accompanied by alcohol use, but they might also be using harder drugs. (wikihow.com)
Severe8
- Severe poisoning can result in death. (rspca.org.uk)
- In a few cases, severe food poisoning can mean a visit to the doctor or hospital. (kidshealth.org)
- Organophosphate poisoning symptoms can range from mild to severe and vary widely depending on the type and degree of exposure. (medicalnewstoday.com)
- Severe poisoning symptoms include difficulty in breathing, irritability, loss of consciousness, and other neurologic symptoms. (news-medical.net)
- On the other hand, prolonged exposure and severe poisoning may result in death. (news-medical.net)
- Severe CO poisoning may require putting the patient in a full-body and high-pressure chamber, wherein the machine forces oxygen into the body. (news-medical.net)
- In severe cases, alcohol poisoning is life-threatening. (medicalnewstoday.com)
- Resin in poison ivy leaves and stems causes severe itching that often persists for three weeks. (garden.org)
Suspect13
- If you suspect CO poisoning, get outside to fresh air immediately, and then call 911. (cpsc.gov)
- If you suspect someone has alcohol poisoning, call for emergency medical help right away. (mayoclinic.org)
- If you suspect that someone has alcohol poisoning - even if you don't see the classic signs and symptoms - seek immediate medical care. (mayoclinic.org)
- If you know, or even suspect, that a child has eaten tablets, you should consult a hospital's emergency department or a poison control center regarding a possible iron poisoning. (webmd.com)
- Call your doctor, local poison control center, or go directly to the closest hospital's emergency department if you suspect your child has swallowed iron-containing vitamins, even if your child shows no symptoms . (webmd.com)
- If you suspect alcohol poisoning, dial 999 immediately to request an ambulance. (www.nhs.uk)
- If you suspect a poisoning, don't take a chance. (ohsu.edu)
- If you suspect CO poisoning, let the patient get fresh air immediately. (news-medical.net)
- [1] If you know or suspect that you or someone else has been poisoned, stay calm and get medical help immediately. (wikihow.com)
- If you know or suspect that you or someone else has been poisoned and you/they are showing symptoms, it's important to get medical help immediately. (wikihow.com)
- If you suspect that a person has deliberately taken medication, drugs, or poison to hurt themselves, call emergency services immediately. (wikihow.com)
- Ukraine's interior minister said on Tuesday a suspect in the Skripal poisoning case, working for Russian military intelligence, had been identified in Ukraine as a man who helped the former Ukrainian president flee to Russia in 2014. (japantimes.co.jp)
- A prime suspect in the poisoning of former Russian agent Alexander Litvinenko appears to have broken his silence to say he will cooperate with a British inquiry into the death. (japantimes.co.jp)
Exposure14
- Chronic poisoning is long-term repeated or continuous exposure to a poison where symptoms do not occur immediately or after each exposure. (wikipedia.org)
- Chronic poisoning most commonly occurs following exposure to poisons that bioaccumulate , or are biomagnified , such as mercury , gadolinium, and lead . (wikipedia.org)
- Exposure to radioactive substances can produce radiation poisoning , an unrelated phenomenon. (wikipedia.org)
- The tendency for poison ivy resin to darken into a "black, shiny, varnish-like substance" on exposure to air was recorded at least as early as 1923 by McNair. (medscape.com)
- Mallory and colleagues hypothesized that black-spot poison ivy is relatively rare because exposure to concentrated sap is required. (medscape.com)
- The symptoms of exposure to low levels of carbon monoxide can be similar to those of food poisoning and flu . (www.nhs.uk)
- Lead poisoning is a preventable condition that results from environmental exposure to lead. (labtestsonline.org)
- Poisoning can occur after short or long-term exposure. (medicalnewstoday.com)
- The prognosis of CO poisoning depends on the duration of exposure, the time between the exposure and the administration of treatment, and the severity of the symptoms. (news-medical.net)
- If the poisoning is mild and the duration of exposure is short, the patient may recover completely. (news-medical.net)
- What's the difference between having mercury exposure and mercury poisoning? (scientificamerican.com)
- A person whose poison control center report indicates an exposure to carbon monoxide (Call type= exposure, Substance = carbon monoxide) with minor, moderate, or major health effects (Medical outcome = minor, moderate, major, death). (cdc.gov)
- S3) A report of a patient with an environmental exposure consistent with CO poisoning. (cdc.gov)
- S7) Poison Control Center (PCC) Data: A record of a case with "exposure" recorded as the type of call, when the exposure substance was carbon monoxide, AND a minor medical outcome was reported. (cdc.gov)
Unintentional4
- Keeping potentially dangerous substances out of little hands is a sure way to prevent unintentional poisoning. (healthfinder.gov)
- CO poisoning is a leading cause of unintentional poisoning deaths in the United States. (cdc.gov)
- Unintentional, non-fire related CO poisoning is responsible for approximately 450 deaths and 21,000 emergency department (ED) visits each year. (cdc.gov)
- Poisoning is the third leading cause of unintentional injury death among children ages 1 to 19 years. (safekids.org)
Rodent1
- If you think your rodent¿s been poisoned, contact your vet immediately. (rspca.org.uk)
Arsenic6
- Given its common use for this purpose throughout much of recorded history, arsenic has often been labeled the King of Poisons. (jhu.edu)
- For example, the high arsenic content of drinking water in Bangladesh and West Bengal, India, is poisoning millions of people today. (jhu.edu)
- Arsenic poisoning , harmful effects of various arsenic compounds on body tissues and functions. (britannica.com)
- Arsenic poisoning in humans most often results from the ingestion or inhalation of insecticides containing arsenious oxide, copper acetoarsenite, or calcium or lead arsenate. (britannica.com)
- Definitive diagnosis of arsenic poisoning is based on the finding of arsenic in the urine and in hair or nails. (britannica.com)
- Natural arsenic deposits are a major health hazard in Bangladesh and West Bengal, where the poison contaminates groundwater from shallow tube wells. (newscientist.com)
Main content1
- Poison in Nature main content. (amnh.org)
Signs3
- What Are the Signs & Symptoms of Poison Ivy? (kidshealth.org)
- Signs of poisoning include weakness, collapse, tremors or twitching and a fast or slow heart rate. (rspca.org.uk)
- What Are the Signs & Symptoms of Food Poisoning? (kidshealth.org)
Poisonous3
- More poisonous than these, but still not near the top of the tree, is tetrodotoxin , the pufferfish toxin that poisons around 50 Japanese people every year. (businessinsider.com)
- Snakeroot poisoning , illness in humans and grazing animals caused by trematol, a poisonous alcohol present in white snakeroot ( Ageratina altissima ), a plant found in North America . (britannica.com)
- Not all medicines and household chemicals are poisonous and not all exposures necessarily poison your child. (montgomerycountymd.gov)
Occurs when a person3
- Iron poisoning occurs when a person, usually a child, swallows a large number of iron-containing pills, most often vitamins . (webmd.com)
- Lead poisoning occurs when a person swallows, absorbs, or inhales lead in any form. (encyclopedia.com)
- Lead poisoning occurs when a person swallows or inhales lead in any form, damaging the brain, nerves, and many other parts of the body. (faqs.org)
Seizures1
- Symptoms of poisoning include the sudden onset of unconsciousness, seizures, confusion or illness when access to poisons, drugs, cleaning fluids or other chemicals is possible. (montgomerycountymd.gov)
Deadly poisons1
- Whether you're talking about Spider-man's archenemy or the deadly poisons that animals and insects use to kill their prey, venom most often conjures up negative thoughts. (popularmechanics.com)
Content1
- In rat poison, the amount of fluoride content varied as different manufacturers developed their own proprietary formulas. (ehow.com)
Humans5
- There are some things which we, as humans, do not think of as poisons. (tripod.com)
- Join host Mark Siddall with chemist Mandë Holford , biologist Marymegan Daly , and medical toxicologist Dr. Rama Rao for a series of presentations unraveling how ocean life has adapted to poison, how poisons found in the ocean can be beneficial to humans, and how families can explore the ocean together safely. (amnh.org)
- That's the number of humans who could-theoretically-succumb to the poison secreted by all of these frogs. (amnh.org)
- Humans first began using poison in warfare thousands of years ago. (merriam-webster.com)
- Foodborne disease, referred to as food poisoning, is carried or transmitted to humans by food containing harmful substances. (eatright.org)
Deaths5
- For slowly developing residential CO problems, occupants and/or physicians can mistake mild to moderate CO poisoning symptoms for the flu, which sometimes results in tragic deaths. (cpsc.gov)
- According to the National Center for Environmental Health, there were about 200 deaths from lead poisoning in the United States between 1979 and 1998. (encyclopedia.com)
- And there were 7,919 accident and poisoning deaths listed as Coronavirus deaths. (freerepublic.com)
- According to the Center for Disease Control and Prevention (CDC) and other global organizations, a high number of deaths occurred as a result of CO poisoning globally during the last decade. (news-medical.net)
- Alcohol poisoning deaths can happen to people of any age. (csbsju.edu)
Germs4
- Germs that cause food poisoning can survive in many places and spread around your kitchen . (cdc.gov)
- This list provides the symptoms, when symptoms begin, and common food sources for germs that cause food poisoning. (cdc.gov)
- When people eat or drink something that's contaminated with germs, they can get sick with food poisoning. (kidshealth.org)
- What Germs Cause Food Poisoning? (kidshealth.org)
ALCOHOL POISONING20
- Alcohol poisoning is a serious - and sometimes deadly - consequence of drinking large amounts of alcohol in a short period of time. (mayoclinic.org)
- Alcohol poisoning can also occur when adults or children accidentally or intentionally drink household products that contain alcohol. (mayoclinic.org)
- A person with alcohol poisoning needs immediate medical attention. (mayoclinic.org)
- A person with alcohol poisoning who is unconscious or can't be awakened is at risk of dying. (mayoclinic.org)
- Never assume the person will sleep off alcohol poisoning. (mayoclinic.org)
- Because alcohol poisoning affects the way the gag reflex works, someone with alcohol poisoning may choke on his or her own vomit and not be able to breathe. (mayoclinic.org)
- Ethyl alcohol poisoning generally results from drinking too many alcoholic beverages, especially in a short period of time. (mayoclinic.org)
- A major cause of alcohol poisoning is binge drinking - a pattern of heavy drinking when a male rapidly consumes five or more alcoholic drinks within two hours, or a female rapidly consumes at least four drinks within two hours. (mayoclinic.org)
- Alcohol poisoning is a leading cause of poisoning in England, especially among young people. (www.nhs.uk)
- Alcohol poisoning can also occur if a person drinks household products that contain alcohol. (www.nhs.uk)
- Alcohol poisoning can be life-threatening and usually requires urgent medical treatment. (medicalnewstoday.com)
- Binge drinking is a common cause of alcohol poisoning. (medicalnewstoday.com)
- Alcohol poisoning is a serious condition. (medicalnewstoday.com)
- Even when someone stops drinking, there is risk of alcohol poisoning for some time afterward. (medicalnewstoday.com)
- Alcohol poisoning can cause drinkers to lose consciousness when their blood alcohol concentration reaches a certain level. (medicalnewstoday.com)
- This article focuses on the medical aspects of alcohol poisoning, rather than other environmental dangers of alcohol abuse such as getting into fights, losing possessions, or having problems with the law. (medicalnewstoday.com)
- If a person is thought to have alcohol poisoning, an ambulance should be called. (medicalnewstoday.com)
- Alcohol poisoning is an overdose of alcohol. (csbsju.edu)
- Alcohol poisoning is deadly. (csbsju.edu)
- Alcohol poisoning is not pretty - it involves crude, bodily functions, bad smell, and messes. (csbsju.edu)
Chronic2
- Chronic lead poisoning - a common problem in children - occurs when small amounts of lead are taken in over a longer period. (encyclopedia.com)
- People with health conditions (like chronic kidney disease) or weakened immune systems are more at risk of getting ill from food poisoning than people who are in good health. (kidshealth.org)
Https1
- You can also get quick information about poisons at https://www.poisonhelp.org/help . (wikihow.com)
Mild2
- Food poisoning symptoms can be anywhere from mild to very serious. (cdc.gov)
- For mild poisoning, the administration of oxygen may be enough to curb the condition. (news-medical.net)
Exposures2
- Good Samaritan Regional Poison Center in Phoenix receives thousands of calls every year concerning harmful substance exposures. (phoenix.gov)
- The CDC report notes that the data does not provide a "definite link" between poison exposures and coronavirus cleaning efforts but acknowledges that "there appears to be a clear temporal association with increased use of these products. (aarp.org)
Food26
- Following four simple steps external icon at home-Clean, Separate, Cook, and Chill-can help protect you and your loved ones from food poisoning. (cdc.gov)
- If you have symptoms of food poisoning, such as diarrhea or vomiting, drink plenty of fluids to prevent dehydration (not having enough water in your body). (cdc.gov)
- Noun a jar of rat poison The killer gave her victims food laced with poison . (merriam-webster.com)
- Sometimes, it's not always easy to tell the difference between food poisoning and influenza, especially since both show similar symptoms. (eatright.org)
- Everyone can reduce their risk of food poisoning by properly handling food and following the Four Simple Steps: wash, separate, cook and refrigerate. (eatright.org)
- Although everyone is at risk for contracting food poisoning, certain vulnerable populations are even more susceptible to food poisoning, so be extra careful if you are high risk or handling food for those at a higher risk including older adults, pregnant women, younger children and those with weakened immune systems. (eatright.org)
- Both food poisoning and the flu can be very serious, so if you think you are ill, especially if you have a fever, see your health-care provider. (eatright.org)
- Two weeks ago I suffered from campylobacter enteris food poisoning . (netdoctor.co.uk)
- What Is Food Poisoning? (kidshealth.org)
- Usually, doctors use "food poisoning" to describe an illness that comes on quickly after eating contaminated food. (kidshealth.org)
- The good news is, food poisoning usually goes away quickly too. (kidshealth.org)
- When people need medical treatment for food poisoning, it's often because of dehydration . (kidshealth.org)
- Getting dehydrated is the most common serious complication of food poisoning. (kidshealth.org)
- How food poisoning shows up depends on the germ that caused it. (kidshealth.org)
- In rare cases, food poisoning can make someone feel dizzy, have blurry vision, or notice tingling in the arms. (kidshealth.org)
- In very rare cases, the weakness that sometimes goes along with food poisoning will cause trouble breathing. (kidshealth.org)
- Even water can cause food poisoning. (kidshealth.org)
- Salmonella bacteria are the leading cause of food poisoning in the United States. (kidshealth.org)
- Salmonella food poisoning, salmonellosis, affects two to four million Americans each year. (faqs.org)
- Salmonella food poisoning results from the growth of the bacterium in food. (faqs.org)
- The rapid increase in the number of bacteria in the intestinal tract overwhelms the defensive capabilities of the host and produces the symptoms of food poisoning. (faqs.org)
- Salmonella enteriditis is of particular concern in food poisoning. (faqs.org)
- When mixed into grain or other food, rats will readily consume the poison and die. (ehow.com)
- Fortunately, there are glimmers of hope that at least some parts of the world are waking up to the obvious dangers associated with poisoning our food, our ecosystem and ourselves. (organicconsumers.org)
- The environmental damage extends to the birds and fish who depend on the poisoned bugs for food. (inhabitat.com)
- Federal court officers have recommended a sentence of life in prison for a peanut company executive convicted of selling salmonella-tainted food, a move that attorneys on both sides called "unprecedented" for a food-poisoning case. (japantimes.co.jp)
Victim3
- It is thus not easy for the victim to detect that he or she is being poisoned.As it is a cumulative poison, small doses can be given over a long period of time, eventually killing someone without necessarily arousing suspicion. (jhu.edu)
- Verb How did the murderer poison the victim? (merriam-webster.com)
- Once you get in touch with emergency medical personnel or a poison help hotline, tell them as much as you can about both the poison and the poisoning victim. (wikihow.com)
Childhood lead2
- Since last year, the news agency has identified more than 3,300 U.S. neighborhood areas with documented childhood lead poisoning rates double those found in Flint. (voanews.com)
- He and Markowitz were also expert witnesses in the recent landmark decision on childhood lead poisoning in California, where paint manufacturers were ordered to pay $400 million to the cities of Los Angeles, San Diego, Oakland, San Francisco and a number of counties to remove lead from older homes to stem an epidemic that has afflicted millions of children for decades. (news-medical.net)
Radioactive2
- Most frequently this issue comes up with radioactive poisons ( plutonium ), commonly known poisons ( strychnine ) and extremely carcinogenic substances (any aromatic ). (everything2.com)
- In 2006 former Russian security officer Alexander Litvinenko, a high profile Kremlin critic, died in London after being poisoned with radioactive polonium. (telegraph.co.uk)
Illness3
- These range from bitter-tasting substances called tannins that interfere with digestive enzymes to poisons that can cause illness-or even death. (amnh.org)
- The poison control center said it first started to link illness with the pods earlier this month. (yahoo.com)
- Mark Leibovich, Star Tribune , "Trump's illness is a lesson in humility for a man, and an era, that needs it," 5 Oct. 2020 The absence of humility, Mr. Danforth said, can poison any chance for a collaborative culture. (merriam-webster.com)
Salmonella2
- Salmonella poisoning can infect people in one of two ways. (medicinenet.com)
- Who Is Most at Risk of Salmonella Poisoning? (medicinenet.com)
Toxin2
- This oily, sticky toxin occurs in many plants, including cashews (left) and poison ivy. (amnh.org)
- Just because you're exposed to a toxin doesn't mean you get poisoned. (scientificamerican.com)
Cyanide1
- He was poisoned with cyanide. (merriam-webster.com)
Colorless1
- Follow these guidelines to prevent this colorless, odorless gas from poisoning you and your family. (healthfinder.gov)
Common4
- Below we'll go over some of the more common poisons and provide links to sites where you can find information on the various poisons. (tripod.com)
- The criminal use of the colourless, tasteless compound arsenious oxide as a poison was common until chemical methods of detection were developed. (britannica.com)
- Eating undercooked ground beef is the most common cause of E. coli poisoning in the United States. (kidshealth.org)
- The most common way that kids get lead poisoning is from lead-based paint in older homes. (kidshealth.org)
Substances4
- In contrast, substances that destroy tissue but do not absorb, such as lye , are classified as corrosives rather than poisons. (wikipedia.org)
- In the medical sense, toxicity and poisoning can be caused by less dangerous substances than those legally classified as a poison. (wikipedia.org)
- A normal physical exam and no symptoms for 6 hours tells the doctor that the child has experienced either little poisoning or did not eat any iron-containing substances. (webmd.com)
- In general, the official "poison" label is given to relatively few substances in order to not to cause inflation of the value of the label. (everything2.com)
Doses1
- Organophosphate poisoning can occur if a person is exposed to the chemicals in high doses or over a long time. (medicalnewstoday.com)
Vomiting2
- Do not induce vomiting unless instructed to do so by the poison control center or medical personnel. (montgomerycountymd.gov)
- You should not induce vomiting unless directed to by a poison control authority or your physician. (montgomerycountymd.gov)
Depends1
- The amount of iron that will cause poisoning depends upon the size of the child. (webmd.com)
Power of poison7
- Join Curator Mark Siddall for a dynamic program that expands on the Museum's exhibition The Power of Poison and offers family-friendly activities. (amnh.org)
- Come explore this hands-on station where you will have the chance to touch and observe specimens and learn about the power of poison. (amnh.org)
- Part of the The Power of Poison exhibition. (amnh.org)
- Visit The Power of Poison exhibition for more about poison in nature. (amnh.org)
- Just like Dorothy's green-faced foe, the American Museum of Natural History has become besotted with the power of poison. (fastcompany.com)
- Much of the 150-year-old museum is filled with Teddy Roosevelt-era taxidermy, but the design of Power of Poison is thoroughly modern, featuring touch-screen installations and an "enchanted book" with animated illustrations. (fastcompany.com)
- The Power of Poison is on view at the American Museum of Natural History until August 10th, 2014. (fastcompany.com)
Toxicity1
- Most reported cases of human poisoning involve the ingestion of jequirity beans, which predominantly cause gastrointestinal toxicity. (springer.com)
Risk Factors1
- This article looks at organophosphate poisoning, how to recognize it, the risk factors, and what to do if poisoning occurs. (medicalnewstoday.com)
20206
- Brian T. Allen, National Review , "The Covid Hydra Bites a Baltimore Museum," 30 Oct. 2020 So far, the other candidates have ignored him and saved their poison darts for each other. (merriam-webster.com)
- Catrin Einhorn, New York Times , "Wolverines Don't Require Protection, U.S. Officials Rule," 8 Oct. 2020 High-profile critics and rivals of Russian President Vladimir Putin have a tendency to die from poison . (merriam-webster.com)
- Jonathan Tobin, Washington Examiner , "Don't bet on a return to normalcy," 5 Nov. 2020 The move will further poison the working environment of media outlets in each other's country. (merriam-webster.com)
- Stephen Collinson And Caitlin Hu, CNN , "What global readers want to hear from Biden and Trump on the debate stage," 22 Oct. 2020 Earl Gray, Lane's defense attorney, said the request for an upward sentencing departure is an attempt to poison the potential pool of jurors. (merriam-webster.com)
- Rochelle Olson, Star Tribune , "Prosecutors want stiff sentences for ex-cops charged in George Floyd's killing," 12 Oct. 2020 The absence of humility, Danforth said, can poison any chance for a collaborative culture. (merriam-webster.com)
- Mark Leibovich, New York Times , "The Untraveled High Road of Humility, and a President Laid Low," 4 Oct. 2020 Failure to reach one could poison relations between the two sides for years to come. (merriam-webster.com)
Mercury6
- In the past, according to a State of Michigan publication titled Mercury Poisoning, it was used as the active ingredient in ointments, animal worming medicines, antiseptics, disinfectants, diuretics and fungicides. (encyclopedia.com)
- Many people do not take the risk of mercury poisoning seriously because they have played with elemental or liquid mercury or broken thermometers containing mercury without ill health effects. (encyclopedia.com)
- This is because poisoning from elemental mercury is most likely due to inhalation of mercury vapors. (encyclopedia.com)
- Elemental mercury is not easily absorbed by the skin, so touching elemental mercury is usually not enough to cause poisoning. (encyclopedia.com)
- What is mercury poisoning? (scientificamerican.com)
- We asked Jay Schauben , director of the Florida/U.S. Virgin Islands Poison Information Center-Jacksonville, to explain mercury poisoning. (scientificamerican.com)
Local poison2
- Also, call the local poison control helpline for assistance. (news-medical.net)
- Once you're sure the person's (or your own) condition is stable, call your local poison control center or poison help hotline for further instructions. (wikihow.com)
Strychnine1
- On a weight basis, batrachotoxin is 250 times more powerful than the rat poison strychnine. (amnh.org)
Lead to learning di1
- Over the long term, lead poisoning in a child can lead to learning disabilities , behavioral problems, and even mental retardation . (encyclopedia.com)